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European Psychiatry: the Journal of the Association of European Psychiatrists

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https://www.readbyqxmd.com/read/28728096/early-life-stress-explains-reduced-positive-memory-biases-in-remitted-depression
#1
J A Gethin, K E Lythe, C I Workman, A Mayes, J Moll, R Zahn
BACKGROUND: There is contradictory evidence regarding negative memory biases in major depressive disorder (MDD) and whether these persist into remission, which would suggest their role as vulnerability traits rather than correlates of mood state. Early life stress (ELS), common in patients with psychiatric disorders, has independently been associated with memory biases, and confounds MDD versus control group comparisons. Furthermore, in most studies negative biases could have resulted from executive impairments rather than memory difficulties per se...
July 10, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728089/volumetric-and-morphological-characteristics-of-the-hippocampus-are-associated-with-progression-to-schizophrenia-in-patients-with-first-episode-psychosis
#2
R Sauras, A Keymer, A Alonso-Solis, A Díaz, C Molins, F Nuñez, M Rabella, A Roldán, E Grasa, E Alvarez, M J Portella, I Corripio
BACKGROUND: Abnormalities in the hippocampus have been implicated in the pathophysiology of psychosis. However, it is still unclear whether certain abnormalities are a pre-existing vulnerability factor, a sign of disease progression or a consequence of environmental factors. We hypothesized that first-episode psychosis patients who progress to schizophrenia after one year of follow up will display greater volumetric and morphological changes from the very beginning of the disorder. METHODS: We studied the hippocampus of 41 patients with a first-episode psychosis and 41 matched healthy controls...
July 5, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728093/obsessive-compulsive-disorder-in-the-elderly-a-report-from-the-international-college-of-obsessive-compulsive-disorders-icocs
#3
B Dell'Osso, B Benatti, C I Rodriguez, C Arici, C Palazzo, A C Altamura, E Hollander, N Fineberg, D J Stein, H Nicolini, N Lanzagorta, D Marazziti, S Pallanti, M Van Ameringen, C Lochner, O Karamustafalioglu, L Hranov, M Figee, L Drummond, J Grant, D Denys, D Cath, J M Menchon, J Zohar
INTRODUCTION: Obsessive-compulsive disorder (OCD) is a highly disabling condition, with frequent early onset. Adult/adolescent OCD has been extensively investigated, but little is known about prevalence and clinical characterization of geriatric patients with OCD (G-OCD≥65years). The present study aimed to assess prevalence of G-OCD and associated socio-demographic and clinical correlates in a large international sample. METHODS: Data from 416 outpatients, participating in the ICOCS network, were assessed and categorized into 2 groups, age<vs≥65years, and then divided on the basis of the median age of the sample (age<vs≥42years)...
July 4, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728090/remote-mood-monitoring-for-adults-with-bipolar-disorder-an-explorative-study-of-compliance-and-impact-on-mental-health-service-use-and-costs
#4
J Simon, K Budge, J Price, G M Goodwin, J R Geddes
BACKGROUND: Remote monitoring of mood disorders may be an effective and low resource option for patient follow-up, but relevant evidence remains very limited. This study explores real-life compliance and health services impacts of mood monitoring among patients with bipolar disorder in the UK. METHODS: Patients with a diagnosis of bipolar disorder who were registered users of the True Colours monitoring system for at least 12months at study assessment were included in this retrospective cohort study (n=79)...
July 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728095/lifetime-use-of-psychiatric-medications-and-cognition-at-43years-of-age-in-schizophrenia-in-the-northern-finland-birth-cohort-1966
#5
A P Hulkko, G K Murray, J Moilanen, M Haapea, I Rannikko, P B Jones, J H Barnett, S Huhtaniska, M K Isohanni, H Koponen, E Jääskeläinen, J Miettunen
BACKGROUND: Higher lifetime antipsychotic exposure has been associated with poorer cognition in schizophrenia. The cognitive effects of adjunctive psychiatric medications and lifetime trends of antipsychotic use remain largely unclear. We aimed to study how lifetime and current benzodiazepine and antidepressant medications, lifetime trends of antipsychotic use and antipsychotic polypharmacy are associated with cognitive performance in midlife schizophrenia. METHODS: Sixty participants with DSM-IV schizophrenia from the Northern Finland Birth Cohort 1966 were examined at 43years of age with an extensive cognitive test battery...
June 27, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728091/age-at-the-time-of-onset-of-psychosis-a-marker-of-specific-needs-rather-than-a-determinant-of-outcome
#6
P Golay, L Alameda, N Mebdouhi, P Baumann, C Ferrari, A Solida, P Progin, J Elowe, P Conus
BACKGROUND: While there is suggestion that early onset of psychosis is a determinant of outcome; knowledge regarding correlates of later onset age is more limited. This study explores the characteristics of patients developing psychosis after age 26, towards the end of the usual age range of early intervention programs, in order to identify potential specific needs of such patients. METHODS: Two hundred and fifty-six early psychosis patients aged 18-35 were followed-up prospectively over 36 months...
June 21, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728098/longitudinal-study-of-religiosity-and-mental-health-of-adolescents-with-psychiatric-problems-the-trails-study
#7
W van der Jagt-Jelsma, M de Vries-Schot, P Scheepers, P A M van Deurzen, H Klip, J K Buitelaar
PURPOSE: This study used longitudinal data to examine the influence of the religiosity of pre-adolescents with psychiatric problems on the course of mental health during adolescence. METHODS: In the TRAILS clinical cohort of 543 pre-adolescents (10-12 years), mental health problems were assessed using self-report at baseline, T2 (12-14 years), T3 (14-17 years), and T4 (17-21 years). The Youth Self Report (YSR) was used at baseline, T2, and T3, and the Adult Self Report (ASR) was used at T4...
June 15, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728097/nonlinear-modulation-of-interacting-between-comt-and-depression-on-brain-function
#8
L Gong, C He, Y Yin, Q Ye, F Bai, Y Yuan, H Zhang, L Lv, H Zhang, Z Zhang, C Xie
BACKGROUND: The catechol-O-methyltransferase (COMT) gene is related to dopamine degradation and has been suggested to be involved in the pathogenesis of major depressive disorder (MDD). However, how this gene affects brain function properties in MDD is still unclear. METHODS: Fifty patients with MDD and 35 cognitively normal participants underwent a resting-state functional magnetic resonance imaging scan. A voxelwise and data-drive global functional connectivity density (gFCD) analysis was used to investigate the main effects and the interactions of disease states and COMT rs4680 gene polymorphism on brain function...
June 9, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28738292/u-shaped-relationship-between-depression-and-body-mass-index-in-the-korean-adults
#9
J-H Lee, S K Park, J-H Ryoo, C-M Oh, J-M Choi, R S McIntyre, R B Mansur, H Kim, S Hales, J Y Jung
BACKGROUND: Although a number of studies have examined the relationship between depression and obesity, it is still insufficient to establish the specific pattern of relationship between depression and body mass index (BMI) categories. Thus, this study was aimed to investigate the relationship between depression and BMI categories. METHODS: A cross-sectional study was conducted for a cohort of 159,390 Korean based on Kangbuk Samsung Health Study (KSHS). Study participants were classified into 5 groups by Asian-specific cut-off of BMI (18...
June 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728094/modelling-a-budgetary-impact-analysis-for-funding-drug-based-smoking-cessation-therapies-for-patients-with-major-depressive-disorder-in-spain
#10
J Rejas-Gutiérrez, E Bruguera, S Cedillo
BACKGROUND: Smoking is associated with high healthcare resource utilisation and cost to society. Patients with major depressive disorder (MDD) exhibit high susceptibility to nicotine dependence. Varenicline, bupropion and nicotine replacement therapy are all indicated for smoking cessation; however funding by the Spanish national health system (SNHS) is limited. We modelled a budgetary impact analysis (BIA) to estimate the impact of the SNHS funding drug-based therapies for smoking cessation in smokers with MDD...
June 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728092/checking-the-predictive-accuracy-of-basic-symptoms-against-ultra-high-risk-criteria-and-testing-of-a-multivariable-prediction-model-evidence-from-a-prospective-three-year-observational-study-of-persons-at-clinical-high-risk-for-psychosis
#11
M P Hengartner, K Heekeren, D Dvorsky, S Walitza, W Rössler, A Theodoridou
BACKGROUND: The aim of this study was to critically examine the prognostic validity of various clinical high-risk (CHR) criteria alone and in combination with additional clinical characteristics. METHODS: A total of 188 CHR positive persons from the region of Zurich, Switzerland (mean age 20.5 years; 60.2% male), meeting ultra high-risk (UHR) and/or basic symptoms (BS) criteria, were followed over three years. The test battery included the Structured Interview for Prodromal Syndromes (SIPS), verbal IQ and many other screening tools...
June 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28692910/beyond-symptom-monitoring-consumer-needs-for-bipolar-disorder-self-management-using-smartphones
#12
J Nicholas, K Boydell, H Christensen
OBJECTIVES: To investigate the potential use of smartphone apps to support self-management in young adults with bipolar disorder. METHODS: We recruited 89 young adults (18-30 years) with bipolar disorder to complete a cross-sectional online survey. The survey contained quantitative and qualitative questions regarding technology use, current use of disorder-management apps, types of apps desired for disorder management, and app features that users would consider important when selecting apps...
June 1, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28646732/effects-of-stimulants-and-atomoxetine-on-emotional-lability-in-adults-a-systematic-review-and-meta-analysis
#13
T R Moukhtarian, R E Cooper, E Vassos, P Moran, P Asherson
BACKGROUND: Emotional lability (EL) is an associated feature of attention-deficit/hyperactivity disorder (ADHD) in adults, contributing to functional impairment. Yet the effect of pharmacological treatments for ADHD on EL symptoms is unknown. We conducted a systematic review and meta-analysis to examine the effects of stimulants and atomoxetine on symptoms of EL and compare these with the effects on core ADHD symptoms. METHODS: A systematic search was conducted on the databases Embase, PsychInfo, and Ovid Medline(®) and the clinicaltrials...
May 25, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28646731/the-adaptive-decision-making-risky-decision-and-decision-making-style-of-internet-gaming-disorder
#14
C-H Ko, P-W Wang, T-L Liu, C-S Chen, C-F Yen, J-Y Yen
BACKGROUND: Persistent gaming, despite acknowledgment of its negative consequences, is a major criterion for individuals with Internet gaming disorder (IGD). This study evaluated the adaptive decision-making, risky decision, and decision-making style of individuals with IGD. METHODS: We recruited 87 individuals with IGD and 87 without IGD (matched controls). All participants underwent an interview based on the Diagnostic and Statistical Manual of Mental Disorders (5th Edition) diagnostic criteria for IGD and completed an adaptive decision-making task; the Preference for Intuition and Deliberation Scale, Chen Internet Addiction Scale, and Barratt Impulsivity Scale were also assessed on the basis of the information from the diagnostic interviews...
May 25, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28641215/worry-and-cognitive-control-predict-course-trajectories-of-anxiety-in-older-adults-with-late-life-depression
#15
P Spinhoven, D C van der Veen, R C Oude Voshaar, H C Comijs
BACKGROUND: Many older adults with depressive disorder manifest anxious distress. This longitudinal study examines the predictive value of worry as a maladaptive cognitive emotion regulation strategy, and resources necessary for successful emotion regulation (i.e., cognitive control and resting heart rate variability [HRV]) for the course of anxiety symptoms in depressed older adults. Moreover, it examines whether these emotion regulation variables moderate the impact of negative life events on severity of anxiety symptoms...
May 19, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28645055/c-reactive-protein-and-white-blood-cell-levels-in-schizophrenia-bipolar-disorders-and-depression-associations-with-mortality-and-psychiatric-outcomes-a-population-based-study
#16
H T Horsdal, O Köhler-Forsberg, M E Benros, C Gasse
BACKGROUND: Mental disorders have been associated with increased levels of inflammatory markers, which can affect disease trajectories. We aimed to assess levels of C-reactive protein (CRP) and white blood cells (WBC) across individuals with schizophrenia, bipolar disorder, and depression, and to investigate associations with subsequent psychiatric admission and mortality. METHODS: We identified all adults in the Central Denmark Region during 2000-2012 with a first diagnosis of schizophrenia, bipolar disorder, or depression and a baseline measurement of CRP and/or WBC count...
May 17, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28641213/measurement-properties-of-screening-and-diagnostic-tools-for-autism-spectrum-adults-of-mean-normal-intelligence-a-systematic-review
#17
A Baghdadli, F Russet, L Mottron
BACKGROUND: The autism spectrum (AS) is a multifaceted neurodevelopmental variant associated with lifelong challenges. Despite the relevant importance of identifying AS in adults for epidemiological, public health, and quality of life issues, the measurement properties of the tools currently used to screen and diagnose adults without intellectual disabilities (ID) have not been assessed. OBJECTIVES: This systematic review addresses the accuracy, reliability, and validity of the reported AS screening and diagnostic tools used in adults without ID...
May 17, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28646733/walls-and-laws-structural-barriers-to-forensic-psychiatric-research
#18
EDITORIAL
G Meynen
No abstract text is available yet for this article.
May 15, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28645056/serious-delinquency-and-later-schizophrenia-a-nationwide-register-based-follow-up-study-of-finnish-pretrial-15-to-19-year-old-offenders-sent-for-a-forensic-psychiatric-examination
#19
N Lindberg, J Miettunen, A Heiskala, R Kaltiala-Heino
BACKGROUND: Aggressive and disruptive behaviors often precede the onset of schizophrenia. In this register-based follow-up study with a case-control design, we wanted to investigate if serious delinquency was associated with future diagnoses of schizophrenia or schizoaffective disorder (here, broadly defined schizophrenia) among a nationwide consecutive sample of 15- to 19-year-old Finnish delinquents sent for a forensic psychiatric examination in 1989-2010. METHODS: The sample comprised 313 delinquents with no past or current psychotic disorder...
May 15, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28641216/psychoeducational-groups-for-adults-with-adhd-and-their-significant-others-pegasus-a-pragmatic-multicenter-and-randomized-controlled-trial
#20
T Hirvikoski, T Lindström, J Carlsson, E Waaler, J Jokinen, S Bölte
OBJECTIVE: To examine the feasibility, efficacy, and effectiveness of PEGASUS, a group-based structured psychoeducation for adults with ADHD and their significant others. METHOD: A pragmatic parallel group add-on design multicenter randomized controlled trial was conducted, comparing an 8-session treatment with PEGASUS (allocated n=97; 48 with ADHD and 49 with significant others) to treatment as usual (TAU, allocated n=82; 39 with ADHD and 43 significant others)...
May 9, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
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