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Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association

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https://www.readbyqxmd.com/read/28734662/transient-global-cerebral-ischemia-induces-rnf213-a-moyamoya-disease-susceptibility-gene-in-vulnerable-neurons-of-the-rat-hippocampus-ca1-subregion-and-ischemic-cortex
#1
Mika Sato-Maeda, Miki Fujimura, Sherif Rashad, Yuiko Morita-Fujimura, Kuniyasu Niizuma, Hiroyuki Sakata, Shuntaro Ikawa, Teiji Tominaga
The RING finger protein 213 (RNF213) is an important susceptibility gene for moyamoya disease (MMD) and is also implicated in other types of intracranial major artery stenosis/occlusion (ICAS); however, the role of RNF213 in the development of ICAS including MMD is unclear. The constitutive expression of the RNF213 gene is relatively weak in brain tissue, while information regarding the expression patterns of the RNF213 gene under cerebral ischemia, which is one of characteristic pathologies associated with ICAS, is currently limited...
July 19, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28733124/left-upper-lung-lobectomy-is-an-embolic-risk-factor-for-cerebral-infarction
#2
Yuya Kobayashi, Hiroyuki Yahikozawa, Ryota Takamatsu, Rie Watanabe, Kenichi Hoshi, Wataru Ishii, Shunichi Sato
Cerebral embolism is typically caused by a cardiogenic thrombus. The patent foramen ovale is a well-known cause of paradoxical embolism. However, some idiopathic cases of stroke have been reported. Such strokes are designated as embolic stroke of undetermined sources. Among them, lung lobectomy may be a new embolic risk factor for cerebral embolism. The risk of thrombus formation is high at the pulmonary vein stump after lung lobectomy, especially in the left upper lobe. Interestingly, the risk remains several years after surgery...
July 19, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28733122/the-effect-of-eosinopenia-on-mortality-in-patients-with-intracerebral-hemorrhage
#3
Asli Bolayir, Burhanettin Cigdem, Seyda Figul Gokce, Hasan Ata Bolayir, Ozlem Kayim Yildiz, Ertugrul Bolayir, Suat Ahmet Topaktas
INTRODUCTION: Inflammation may determine the prognosis of intracerebral hemorrhage (ICH), which has high mortality and morbidity rates. Recent studies have increasingly demonstrated eosinopenia as a prognostic factor, particularly in bacteremia, chronic obstructive pulmonary disease, and myocardial and cerebral infarction. Nonetheless, its significance regarding the determination of prognosis in patients with ICH has not yet been clarified. MATERIALS AND METHODS: Our study included 296 patients who presented to our clinic within 24 hours of the onset of symptoms and who were diagnosed with ICH between January 2008 and June 2016, along with 180 age- and sex-matched controls...
July 19, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28733121/paradoxical-embolism-in-a-girl-with-atrial-septal-defect-after-paroxysmal-supraventricular-tachycardia-ablation
#4
Xiang Chen, Zhijun Zhu, Danning Wu
Paradoxical embolism is a kind of important pathogenesis of cardiocerebrovascular diseases. In our case, radiofrequency current catheter ablation was accomplished successfully in a 15-year-old girl who had been experiencing supraventricular tachycardia for 6 months. She presented with abrupt onset of left hemiplegia and loss of consciousness on the first postoperative day. An urgent cerebral computed tomography showed a hyperdense right middle cerebral artery. Transthoracic echocardiogram examination revealed an atrial septal defect (ASD), with the diameter measuring 39 mm...
July 19, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28733123/augmentative-and-alternative-communication-effects-on-quality-of-life-in-patients-with-locked-in-syndrome-and-their-caregivers
#5
Francesco Corallo, Lilla Bonanno, Viviana Lo Buono, Simona De Salvo, Carmela Rifici, Patrizia Pollicino, Cettina Allone, Rosanna Palmeri, Antonino Todaro, Antonella Alagna, Alessia Bramanti, Placido Bramanti, Silvia Marino
BACKGROUND: The aim of this study was to evaluate the impact of the augmentative and alternative communication system on anxiety and depression performances and the quality of life (QoL) of patients who have the locked-in syndrome (LIS) and that of their caregivers. METHOD: We enrolled 15 patients and their principal caregivers. The assessment consisted of the administration of the employed Short Form-36 Questionnaire for the assessment of QoL, the Hamilton Anxiety Rating Scale (HAM-A) for anxiety, and the Beck Depression Inventory for depression...
July 18, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28716586/comparison-of-three-dimensional-t1-weighted-magnetic-resonance-and-contrast-enhanced-ultrasound-plaque-images-for-severe-stenosis-of-the-cervical-carotid-artery
#6
Yasuyoshi Shimada, Kohki Oikawa, Shunrou Fujiwara, Yasushi Ogasawara, Yuiko Sato, Shinsuke Narumi, Tadayoshi Kato, Kazumasa Oura, Yasuo Terayama, Makoto Sasaki, Kentaro Fujimoto, Jun Yoshida, Kuniaki Ogasawara
BACKGROUND AND PURPOSE: Magnetic resonance (MR) and contrast-enhanced ultrasound assess characteristics and neovascularization, respectively, of the carotid plaque. The purpose of the present study was to clarify how findings of contrast-enhanced ultrasound plaque imaging are related to those of 3-dimensional (3D) fast spin echo (FSE) T1-weighted MR plaque imaging (WI) in severe stenosis (≥70%) of the cervical carotid artery. METHODS: Fifty-three patients underwent 3D FSE T1-WI and contrast-enhanced ultrasound...
July 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28716585/ascertainment-of-alaska-native-stroke-incidence-2005-2009-lessons-for-assessing-the-global-burden-of-stroke
#7
Bernadette Boden-Albala, James Allen, Eric T Roberts, Lisa Bulkow, Brian Trimble
BACKGROUND: Stroke is a critical public health issue in the United States and globally. System models to optimally capture stroke incidence in rural and culturally diverse communities are needed. The epidemiological transition to a western lifestyle has been associated with an increased burden of vascular risk factors among Alaska Native (AN) people. The burden of stroke in AN communities remains understudied. METHODS: The Alaska Native Stroke Registry (ANSR) was designed to screen and capture all stroke cases between 2005 and 2009 through its integration into the existing single-payer Alaska Tribal Health System infrastructure...
July 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28716584/p-wave-terminal-force-in-lead-v1-predicts-paroxysmal-atrial-fibrillation-in-acute-ischemic-stroke
#8
Toshiaki Goda, Yukio Sugiyama, Nobuyuki Ohara, Takeshi Ikegami, Kotaro Watanabe, Junya Kobayashi, Daisuke Takahashi
BACKGROUND: Detection of paroxysmal atrial fibrillation (PAF) in cryptogenic stroke is critical to selecting an antithrombotic therapy for preventing recurrent stroke. However, the predictor of PAF in patients with acute ischemic stroke is not well elucidated. P-wave terminal force in lead V1 (PTFV1) is a standard electrocardiogram marker of left atrial abnormality. In this study, we aimed to investigate the utility of PTFV1 for the prediction of PAF in patients with acute ischemic stroke...
July 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28716583/quantitative-analysis-of-geometry-and-lateral-symmetry-of-proximal-middle-cerebral-artery
#9
Roman Peter, Bart J Emmer, Adriaan C G M van Es, Theo van Walsum
BACKGROUND: The purpose of our work is to quantitatively assess clinically relevant geometric properties of proximal middle cerebral arteries (pMCA), to investigate the degree of their lateral symmetry, and to evaluate whether the pMCA can be modeled by using state-of-the-art deformable image registration of the ipsi- and contralateral hemispheres. METHODS: Individual pMCA segments were identified, quantified, and statistically evaluated on a set of 55 publicly available magnetic resonance angiography time-of-flight images...
July 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28712721/comprehensive-cost-of-illness-of-three-major-diseases-in-japan
#10
Kunichika Matsumoto, Simpei Hanaoka, Yinghui Wu, Tomonori Hasegawa
OBJECTIVE: The purpose of this study was to calculate the burden of 3 major diseases (cancer, heart disease, and cerebrovascular disease [CVD]) using the cost of illness (COI) method. METHODS: As a modification of the original COI method developed by Rice, the estimated comprehensive COI (C-COI) of cancer, heart disease, and CVD were redefined. C-COI consists of medical direct, morbidity, and mortality costs (MtCs; components of the original COI); long-term care (LTC) direct cost (DC); and family burden (FB)...
July 13, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28712720/manual-aspiration-thrombectomy-in-patients-with-acute-stroke-related-calcified-cerebral-emboli
#11
Esther Koh, Hyo Sung Kwak, Gyung-Ho Chung
OBJECTIVE: The aim of this study was to evaluate the effectiveness of mechanical aspiration thrombectomy (MAT) in patients with acute ischemic stroke from calcified cerebral emboli. METHODS: Procedural results were reviewed for acute stroke patients with clinically neurological deficits who underwent recanalization from October 2012 through September 2015. Initial imaging studies and cerebral angiography were analyzed. RESULTS: Of the total number of patients with acute stroke, 5 patients were confirmed to have acute ischemic stroke by calcified cerebral emboli...
July 13, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28711363/anticoagulant-free-but-dangerous-perisurgical-consideration
#12
LETTER
Yosuke Aiba, Ryuji Sakakibara, Yohei Tsuyusaki, Masahiko Kishi, Fuyuki Tateno, Tsuyoshi Ogata, Takeki Nagao, Hitoshi Terada, Tsutomu Inaoka
No abstract text is available yet for this article.
July 12, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28711362/response-to-drs-lahiri-and-lyden
#13
LETTER
Adnan I Qureshi, Muhammad F Ishfaq, Haseeb A Rahman, Abraham P Thomas
No abstract text is available yet for this article.
July 12, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28709743/ischemic-stroke-with-cardiac-pacemaker-implantation-comparison-of-physiological-and-ventricular-pacing-modes
#14
Yuji Kato, Takeshi Hayashi, Ritsushi Kato, Norio Tanahashi, Masaki Takao
BACKGROUND: The clinical characteristics of ischemic stroke in patients with a pacemaker (PM) are not well understood. METHODS: Forty-six ischemic stroke patients with a PM were investigated retrospectively, and the impact of different pacing modes was compared. RESULTS: The patients were divided into a physiological pacing group (n = 22) and a ventricular pacing group (n = 24). The prevalence of atrial fibrillation (AF) was significantly higher in the ventricular pacing group (36% versus 75%; P = ...
July 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28709742/age-and-gender-differences-in-the-association-between-serum-25-hydroxyvitamin-d-and-stroke-in-the-general-us-population-the-national-health-and-nutrition-examination-survey-2001-2006
#15
Ji Li, Hong Lai, Lifang Yang, Hong Zhu, Shaoguang Chen, Shenghan Lai
BACKGROUND: Previous findings on the association between serum 25(OH)D level and stroke have been controversial. We aimed to examine whether these controversial findings could be possibly due to difference in study participant characteristics, especially age and gender differences in these studies, by analyzing the data from a representative sample of the general US population. METHODS: Data of 13,642 adults 20 years or older who participated in the 2001-2006 National Health and Nutrition Examination Survey were analyzed in this study...
July 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28694111/the-pathophysiology-of-watershed-infarction-a-three-dimensional-time-of-flight-magnetic-resonance-angiography-study
#16
Caroline Weill, Laurent Suissa, Jacques Darcourt, Marie-Hélène Mahagne
BACKGROUND: Most of the time, watershed infarcts (WIs) involve steno-occlusive carotid disease. The pathophysiological mechanism could be predicted by their pattern: internal WIs (IWIs) are thought to be due to hemodynamic impairment in contrast to cortical WIs (CWIs), which are more likely to be caused by microembolic phenomena. We used a 3D time-of-flight (TOF) magnetic resonance angiography (MRA) study to assess this hypothesis. METHODS: In 45 consecutive patients with a recent WI and ipsilateral cervical carotid stenosis, clinical and radiological data were obtained retrospectively...
July 7, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28694110/predictors-of-in-hospital-mortality-after-decompressive-hemicraniectomy-for-malignant-ischemic-stroke
#17
Saadat Kamran, Abdul Salam, Naveed Akhtar, Aymen Alboudi, Arsalan Ahmad, Rabia Khan, Rashed Nazir, Muhammad Nadeem, Jihad Inshasi, Ahmed ElSotouhy, Ghanim Al Sulaiti, Ashfaq Shuaib
OBJECTIVE: The purpose of this retrospective multicenter, pooled-data analysis was to determine the factors associated with in-hospital mortality in decompressive hemicraniectomy (DHC) for malignant middle cerebral artery (MMCA) stroke. PATIENTS AND METHODS: The authors reviewed pooled DHC database from 3 countries for patients with MMCA with hospital mortality in spite of DHC to identify factors that predicted in-hospital mortality after DHC. The identified factors were applied to the group of patients who were selected for DHC but either refused surgery and died or stabilized and did not undergo DHC...
July 7, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28689999/real-world-outcomes-of-acute-ischemic-stroke-treatment-with-intravenous-recombinant-tissue-plasminogen-activator
#18
Keith A Betts, Dana Hurley, Jinlin Song, Gautam Sajeev, Jenny Guo, Ella Xiaoyan Du, Marco Paschoalin, Eric Q Wu
BACKGROUND AND PURPOSE: In clinical trials, intravenous (IV) recombinant tissue-type plasminogen activator (rt-PA) reduces the likelihood of disability if given within 3 hours of acute ischemic stroke. This study compared real-world outcomes between patients treated and patients not treated with IV rt-PA. METHODS: In this retrospective study, United States-based neurologists randomly selected eligible acute ischemic stroke patients from their charts who were and were not treated with IV rt-PA...
July 6, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28689998/association-between-serum-uric-acid-level-and-activity-of-daily-living-in-japanese-patients-with-ischemic-stroke
#19
Shinya Kawase, Hisanori Kowa, Yutaka Suto, Hiroki Fukuda, Masayoshi Kusumi, Hiroyuki Nakayasu, Kenji Nakashima
BACKGROUND: An association between serum uric acid and outcomes of ischemic stroke has been reported, but the results are controversial. The aim of this study is to clarify how uric acid may affect activities of daily living after acute ischemic stroke. METHODS: Consecutive Japanese patients with acute ischemic stroke were analyzed. Serum uric acid quartiles and activities of daily living at hospitalization and discharge in men and women were examined. Activities of daily living were evaluated using the modified Rankin scale score, and a score of 3 or higher was defined as poor activities of daily living...
July 6, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28688715/multiple-silent-brain-infarcts-are-associated-with-severer-stroke-in-patients-with-first-ever-ischemic-stroke-without-advanced-leukoaraiosis
#20
Da-Wei Chen, Yu-Xi Wang, Jin Shi, Wei-Qing Zhang, Fen Yang, Yan-Wei Yin, Lu-Na Ma
BACKGROUND: Silent brain infarct (SBI) is associated with symptomatic stroke, but the association between SBI and acute ischemic stroke severity is uncertain. We aimed at investigating the association between SBI number and stroke severity in patients with first-ever ischemic stroke without advanced leukoaraiosis. METHODS: This study included 115 patients with first-ever ischemic stroke without advanced leukoaraiosis. National Institutes of Health Stroke Scale (NIHSS) scores were measured...
July 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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