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Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association

journal
https://www.readbyqxmd.com/read/30241925/using-smartphones-to-collect-quantitative-data-on-lower-limb-functionality-in-people-who-have-suffered-a-stroke
#1
Jose Antonio Merchán-Baeza, Manuel González-Sánchez, Antonio Ignacio Cuesta-Vargas
GOAL: The main objective was to use the inertial sensor integrated into a smartphone to collect quantitative data on lower limb functioning during execution of the timed up and go test and sit to stand test by people in the acute stage of stroke. The secondary objective was to analyze whether smartphones provide reliable quantitative data on performance of these functional tests. MATERIAL AND METHODS: Cross-sectional analytical study involving 8 elderly people (M age = 67...
September 18, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30228010/stroke-in-pregnancy-and-review-of-current-literature-arterial-spin-labeling-mri-can-identify-the-presence-and-intensity-of-collateral-circle
#2
Agnese Morello, Tommaso Casseri, Maurizio Acampa, Paolo Galluzzi, Alfonso Cerase, Lucia Monti
Diagnosis and treatment of acute ischemic stroke is challenging during pregnancy. We present a diagnostic strategy in a pregnant woman with suspect of acute stroke. We perform magnetic resonance with arterial spin labeling sequence, an X-ray and contrast medium safe perfusion technique. Arterial spin labeling can detects collateral vessels in patient with acute ischemic stroke. Demonstrating collateral vessels is relevant for better understanding prognosis and for improving the diagnostic assessment in pregnancy...
September 15, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30220629/trends-of-antiplatelet-therapy-for-the-management-of-moyamoya-disease-in-japan-results-of-a-nationwide-survey
#3
Koichi Oki, Masahiro Katsumata, Yoshikane Izawa, Shinichi Takahashi, Norihiro Suzuki, Kiyohiro Houkin
BACKGROUND: The efficacy and safety of antiplatelet drugs in the treatment of moyamoya disease remain unclear. This study reports results of a nationwide survey conducted in 2016 on the trends of antiplatelet therapy for moyamoya disease in Japan. METHODS: Data were obtained through questionnaires related to treatment policies regarding antiplatelet drugs from each specialized stroke management department of 765 hospitals in Japan. Data were also compared between experienced facilities (defined as facilities managing more than 10 cases per year) and those less experienced (not more than 10 cases per year) to determine experts' opinion...
September 14, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30219630/impact-of-plaque-composition-on-risk-of-coronary-artery-diseases-in-patients-with-carotid-artery-stenosis
#4
Saori Hamada, Daina Kashiwazaki, Shusuke Yamamoto, Naoki Akioka, Naoya Kuwayama, Satoshi Kuroda
OBJECT: Recent clinical studies have recently demonstrated a strong association between carotid artery stenosis and coronary artery disease (CAD). However, the clinical impact of carotid plaque composition on CAD remains unclear. This study was aimed to determine the relationship between carotid plaque composition and CAD in patients who underwent carotid endarterectomy (CEA) or carotid artery stenting (CAS). METHODS: This prospective cohort study included a total of 97 patients who were admitted to our institution between January 2012 and April 2016...
September 12, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30219629/clinical-implications-of-basilar-artery-plaques-in-the-pontine-infarction-with-normal-basilar-angiogram-a-high-resolution-magnetic-resonance-imaging-study
#5
Han-Jin Cho, Kyung-Hye Kim, Eun-Joo Kim, Tae Hong Lee, Sang Min Sung, Ji Hoe Heo, Dae Soo Jung
BACKGROUND: Using high-resolution magnetic resonance imaging (HR-MRI), we investigated the impact of basilar artery plaques that were not detected by magnetic resonance angiography (MRA) on the functional outcomes of patients with acute pontine infarction. METHODS: A total of 40 patients with acute pontine infarction and normal basilar findings on MRA prospectively underwent HR-MRI for detection of basilar artery plaques. A relevant plaque was defined as one on the dorsal side of basilar artery, the same side of the ischemic lesion, and the same axial slices of the ischemic lesion...
September 12, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30217637/immune-thrombotic-thrombocytopenic-purpura-is-a-rare-cause-of-ischemic-stroke-in-young-adults-case-reports-and-literature-review
#6
Cyrielle Tomich, Sabrina Debruxelles, Yahsou Delmas, Sharmila Sagnier, Mathilde Poli, Stéphane Olindo, Pauline Renou, François Rouanet, Igor Sibon
INTRODUCTION: Immune thrombotic thrombocytopenic purpura (i-TTP), related to acquired ADAMTS-13 dysfunction, can lead to various neurological symptoms including ischemic stroke. To date the clinical, radiological, and biological characteristics of patients having a stroke as the inaugural manifestation of i-TTP are largely unknown. METHODS: Probable immune-TTP was defined by a low ADAMTS-13 activity associated with the presence of ADAMTS-13 inhibitors and/or favorable clinicobiological response under immunological treatments...
September 12, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30217638/the-effects-of-lipopolysaccharide-on-the-disrupted-blood-brain-barrier-in-a-rat-model-of-preeclampsia
#7
Mutlu Kucuk, Canan Ugur Yilmaz, Nurcan Orhan, Bulent Ahishali, Nadir Arican, Imdat Elmas, Candan Gürses, Mehmet Kaya
BACKGROUND: Preeclampsia is a disorder characterized by high blood pressure and often proteinuria during pregnancy. It is known that a subseptic dose of bacterial lipopolysaccharide (LPS) induces production of proinflammatory cytokines, and possibly increasing the risk for developing preeclampsia. We investigated the effects of LPS on the blood-brain barrier (BBB) integrity in pregnant rats with N(omega)-nitro-l-arginine methyl ester (L-NAME) induced preeclampsia. METHODS: Starting from the 10th day of gestation, pregnant rats were given L-NAME for 10 days to produce hypertension and proteinuria...
September 11, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30217636/analysis-of-risk-factors-increased-hemorrhagic-transformation-after-acute-ischemic-stroke
#8
Wan-Qian Ge, Jie Chen, Hong Pan, Fei Chen, Cheng-Ye Zhou
BACKGROUND: The purpose of this study was to analyze the risk factors of hemorrhagic transformation (HT) after intravenous thrombolysis using a recombinant tissue plasminogen activator (r-tPA) in acute ischemic stroke (AIS). METHODS: We included 199 consecutive patients in the First Affiliated Hospital of Wenzhou Medical University from January 2016 to October 2017 with a diagnosis of AIS. The patients were divided into 2 groups: HT and non-HT. The related risk factors were recruited before and after receiving r-tPA thrombolysis...
September 11, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30205998/prevalence-of-balance-impairment-among-stroke-survivors-undergoing-neurorehabilitation-in-nigeria
#9
Grace Vincent-Onabajo, Hadiza Y Musa, Emmanuel Joseph
BACKGROUND: Poststroke balance impairment adversely affects stroke outcomes and addressing the impairment is expected to constitute an important focus of neurorehabilitation. AIMS: To examine the prevalence and factors associated with balance impairment after stroke. METHODS: Ninety-five stroke survivors undergoing neurorehabilitation at 2 government hospitals in Northern Nigeria participated in this cross-sectional study. Berg Balance Scale (BBS) was used to assess the presence of balance impairment (BBS score of 0-20)...
September 9, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30206000/ischemic-stroke-predictors-in-patients-presenting-with-dizziness-imbalance-and-vertigo
#10
Yongwoo Kim, Mohammad Faysel, Clotilde Balucani, Daohai Yu, Nadege Gilles, Steven R Levine
OBJECTS: To identify predictors of acute ischemic stroke (AIS) among patients presenting to the Emergency Department (ED) with dizziness, imbalance, or vertigo (DIV) based on demographic and clinical characteristics. METHODS: We identified patients admitted to the hospital after presenting to the ED with DIV from the Statewide Planning and Research Cooperative System database of New York from 2010 to 2014. Demographic and clinical characteristics were systematically collected...
September 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30205999/brain-magnetic-resonance-imaging-of-intracerebral-hemorrhagic-rats-after-alcohol-consumption
#11
Li-Chuan Huang, Hock-Kean Liew, Hung-Yu Cheng, Jon-Son Kuo, Wen-Lin Hsu, Cheng-Yoong Pang
BACKGROUND: Alcoholism is one of the risk factors for cerebrovascular diseases. Our previous study demonstrated that acute alcohol intoxication enhances brain injury and neurological impairment in rats suffering from intracerebral hemorrhage (ICH). We plan to investigate the effect of chronic alcohol consumption (CAC) in rats with ICH by magnetic resonance imaging (MRI). METHODS: Sixteen Sprague-Dawley male rats were divided into 2 groups: CAC group (fed with 10% alcohol drinking water for 4 weeks, n = 8), and Control group (plain drinking water, n = 8)...
September 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30205997/antithrombotic-treatment-prior-to-intracerebral-hemorrhage-analysis-in-the-national-acute-stroke-israeli-registry
#12
Roy Romem, David Tanne, Diklah Geva, Michal Einhorn-Cohen, Nir Shlomo, Sara Bar-Yehuda, Sagi Harnof
BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) is the most disastrous stroke subtype. Prognosis is considered worse with prior antithrombotic treatment. Our aim was to evaluate the association of prior antithrombotic treatment on the radiological and clinical outcome after ICH in a subgroup of patients included in a national registry. METHODS: Based on the National Acute Stroke Israeli (NASIS) registry during 2004, 2007, 2010, and 2013 (2-month periods), characteristics, volumetric parameters, and prognosis of a subgroup of patients with ICH were analyzed...
September 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30205996/superficial-temporal-artery-to-anterior-cerebral-artery-hemi-bonnet-bypass-using-radial-artery-graft-for-prevention-of-complications-after-surgical-treatment-of-partially-thrombosed-large-giant-anterior-cerebral-artery-aneurysm
#13
Kojiro Wada, Naoki Otani, Terushige Toyooka, Satoru Takeuchi, Arata Tomiyama, Kentaro Mori
BACKGROUND: Partially thrombosed large/giant aneurysm of the anterior cerebral artery is still challenging because this complex aneurysm requires arterial revascularization in the deep operation field. Therefore, direct neck clipping is often impossible. We describe our experiences with extracranial-intracranial bypass as an insurance bypass prior to clipping of partially thrombosed anterior cerebral artery aneurysms, and discuss the microsurgical technique and strategy. CLINICAL PRESENTATION: Consecutive, single-surgeon experience with the surgical treatment of partially thrombosed anterior cerebral artery aneurysms was retrospectively reviewed...
September 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30205995/edaravone-reduces-iron-mediated-hydrocephalus-and-behavioral-disorder-in-rat-by-activating-the-nrf2-ho-1-pathway
#14
Jianbo Zhang, Xia Shi, Zhi Chen, Junjun Geng, Yuelong Wang, Hua Feng, Gang Zhu, Qianwei Chen
Our previous studies have demonstrated that hemorrhage-derived iron has a key role in causing brain injury after intraventricular hemorrhage (IVH). Based on this finding, we hypothesized that edaravone, a free-radical scavenger, has the potential to alleviate hydrocephalus and neurological deficits post-IVH by suppressing iron-induced oxidative stress. Thus, this study aimed to investigate the efficacy of edaravone for rats with FeCl3 injection, as well as to explore the related molecular mechanism. An experimental model was established in adult male Sprague-Dawley rats via FeCl3 injection into the right lateral ventricle...
September 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30201460/reduction-of-ischemia-reperfusion-related-brain-hemorrhage-by-stachybotrys-microspora-triprenyl-phenol-7-in-mice-with-antioxidant-effects
#15
Yong Huang, Yasuyuki Ohta, Jingwei Shang, Xianghong Li, Xia Liu, Xiaowen Shi, Tian Feng, Toru Yamashita, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Eriko Suzuki, Keiji Hasumi, Koji Abe
BACKGROUND: Stachybotrys microspora triprenyl phenol-7 (SMTP-7) has both thrombolytic and anti-inflammatory effects, but its neuroprotective effects on cerebral ischemia are still unclear. The present study assessed the antioxidative and neurovascular unit (NVU) protective effects of SMTP-7 using transient middle cerebral artery occlusion (tMCAO) mice. METHODS: After 60 minutes tMCAO, 0.9% NaCl, tissue-type plasminogen activator (tPA), SMTP-7 or tPA + SMTP-7 was intravenously administrated through subclavian vein just before the reperfusion, and these mice were examined at 24 hours after reperfusion...
September 7, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30201459/efficacy-and-safety-of-citalopram-for-the-treatment-of-poststroke-depression-a-meta-analysis
#16
REVIEW
Min Cui, Chao Yun Huang, Fang Wang
OBJECTIVE: To objectively evaluate the efficacy and safety of citalopram versus other antidepressant drugs in poststroke depression (PSD) treatment. METHODS: We searched randomized controlled trials (RCTs) that compared citalopram with other Selective serotonin reuptake inhibitors (SSRIs) and Serotonin norepinephrine reuptake inhibitor (SNRIs) on PSD treatment. The methodological quality of RCTs was assessed according to the Cochrane risk of bias tool. Meta-analysis was conducted using RevMan 5...
September 7, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30201458/improving-the-accuracy-of-scores-to-predict-gastrostomy-after-intracerebral-hemorrhage-with-machine-learning
#17
Ravi Garg, Shyam Prabhakaran, Jane L Holl, Yuan Luo, Roland Faigle, Konrad Kording, Andrew M Naidech
BACKGROUND: Gastrostomy placement after intracerebral hemorrhage indicates the need for continued medical care and predicts patient dependence. Our objective was to determine the optimal machine learning technique to predict gastrostomy. METHODS: We included 531 patients in a derivation cohort and 189 patients from another institution for testing. We derived and tested predictions of the likelihood of gastrostomy placement with logistic regression using the GRAVo score (composed of Glasgow Coma Scale ≤12, age >50 years, black race, and hematoma volume >30 mL), compared to other machine learning techniques (kth nearest neighbor, support vector machines, random forests, extreme gradient boosting, gradient boosting machine, stacking)...
September 7, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30201457/screening-for-fabry-disease-in-japanese-patients-with-young-onset-stroke-by-measuring-%C3%AE-galactosidase-a-and-globotriaosylsphingosine
#18
Naoto Kinoshita, Naohisa Hosomi, Hayato Matsushima, Masahiro Nakamori, Yoshiki Yagita, Takemori Yamawaki, Tsuyoshi Torii, Takeshi Kitamura, Yoshimasa Sueda, Ryo Shimomura, Mutsuko Araki, Tomohisa Nezu, Shiro Aoki, Satoshi Ishii, Hiroki Maruyama, Masayasu Matsumoto, Hirofumi Maruyama
BACKGROUND: Fabry disease is an X-linked lysosomal storage disorder caused by mutations in GLA, which encodes the enzyme α-galactosidase A (α-Gal A). Although the prevalence of Fabry disease in patients with stroke has been reported to range from 0% to 4%, few cohort studies have examined Japanese stroke patients. We aimed to clarify the prevalence of Fabry disease and the frequency of GLA mutations among patients with young-onset stroke in Japan. METHODS: From April 2015 to December 2016, we enrolled patients with young-onset (≤60 years old) ischemic stroke or intracerebral hemorrhage...
September 7, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30201456/upper-limb-ischemic-postconditioning-as-adjunct-therapy-in-acute-stroke-patients-a-randomized-pilot
#19
Yuejuan Li, Keke Liang, Long Zhang, Yamei Hu, Yunli Ge, Jianhua Zhao
OBJECTIVE: This study aims to observe the clinical effect of upper limb ischemic postconditioning (LIPostC) as an adjunct to treatment with acute stroke patients, possibly due to increased cerebral perfusion. METHODS: We perform a randomized blinded placebo controlled trial in nonthrombolysis patients with acute ischemic stroke, within 72 hours of ictus, divided into the LIPostC group and control group. The LIPostC group is induced by 4 cycles of intermittent repeated limb ischemia: alternating 5 minutes inflation (20 mm Hg above systolic blood pressure) and 5 minutes deflation performed manually using a standard upper arm blood pressure cuff in the nonparetic arm...
September 7, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30201455/real-world-outcomes-of-acute-ischemic-stroke-treatment-with-intravenous-thrombolysis-a-systematic-review-and-meta-analysis
#20
Bin Qin, Ming-Jun Zhao, Hong Chen, Huixun Qin, Libo Zhao, Lin Fu, Cheng Qin, Mingxiu Yang, Wen Gao
BACKGROUND: Evidence from outside the typical clinical research setting, such as the real-world setting, complements evidence coming from randomized controlled trials. The purpose of this study was to evaluate all available evidence from the real-world observational trials about long-term outcomes of treatment with intravenous (IV) recombinant tissue-type plasminogen activator (rt-PA) compared with not treated with IV rt-PA (non-rt-PA) in patients with acute ischemic stroke. METHODS: We searched PubMed and Embase until March 1, 2018 for observational studies reporting matched or adjusted results comparing IV rt-PA versus non-rt-PA in patients with acute ischemic stroke...
September 7, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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