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Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association

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https://www.readbyqxmd.com/read/30415920/risk-factors-for-hemorrhagic-and-cardioembolic-complications-of-intracerebral-hemorrhage-associated-with-anticoagulants
#1
Sho Osawa, Tatsuya Shimizu, Tadashige Kano, Ryosuke Shintoku, Hiroya Fujimaki, Ken Asakura
BACKGROUND: Patients with intracerebral hemorrhage taking anticoagulants are increasingly common in Japan due to the aging population. The clinical benefit of restarting anticoagulants is established, but the optimal timing of resumption is controversial. Risk factors for hemorrhagic and cardioembolic events in the acute phase are also unknown. This study investigated hemorrhagic and cardioembolic events and risk factors in intracerebral hemorrhage patients taking anticoagulants. METHODS: The clinical data of 65 consecutive intracerebral hemorrhage patients taking anticoagulants were retrospectively reviewed...
November 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30415919/the-influence-of-weather-on-the-incidence-of-primary-spontaneous-intracerebral-hemorrhage
#2
Rajeev Kumar Garg, Bichun Ouyang, Vishal Pandya, Raquel Garcia-Cano, Ivan Da Silva, Deborah Hall, Sayona John, Thomas Pritchett Bleck, Max Berkelhammer
BACKGROUND: Intracerebral hemorrhage has been associated with changes in various weather conditions. The primary aim of this study was to examine the collective influence of temperature, barometric pressure, and dew point temperature on the incidence of primary spontaneous intracerebral hemorrhage (sICH). METHODS: Between January 2013 and December 2016, patients with sICH due to hypertension or amyloid angiopathy with a known time of onset were identified prospectively...
November 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30415918/impact-of-elevated-hemoglobin-a1c-levels-on-functional-outcome-in-patients-with-acute-ischemic-stroke
#3
Hong Wang, Yifan Cheng, Siyan Chen, Xianmei Li, Zhenguo Zhu, Wanli Zhang
BACKGROUND: The association between hemoglobin A1c (HbA1c) and clinical outcomes of acute ischemic stroke is uncertain. We aimed to evaluate the association between initial hemoglobin A1c level and clinical outcome after acute ischemic stroke. METHODS: A total of 408 patients with first-ever acute ischemic stroke were included in this study. We divided the patients into three groups according to HbA1c level: low HbA1c level (HbA1c <5.7%), moderate HbA1c level (HbA1c 5...
November 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30415917/the-role-of-personalized-virtual-reality-in-education-for-patients-post-stroke-a-qualitative-case-series
#4
Angelica G Thompson-Butel, Christine T Shiner, John McGhee, Benjamin John Bailey, Pascal Bou-Haidar, Michael McCorriston, Steven G Faux
BACKGROUND: Education is essential to promote prevention of recurrent stroke and maximize rehabilitation; however, current techniques are limited and many patients remain dissatisfied. Virtual reality (VR) may provide an alternative way of conveying complex information through a more universal language. AIM: To develop and conduct preliminary assessments on the use of a guided and personalized 3D visualization education session via VR, for stroke survivors and primary caregivers...
November 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30415916/hospital-quality-metrics-america-s-best-hospitals-and-outcomes-after-ischemic-stroke
#5
Judith H Lichtman, Erica C Leifheit, Yun Wang, Larry B Goldstein
BACKGROUND: Developing quality metrics to assess hospital-level care and outcomes is increasingly popular in the United States. The U.S. News & World Report ranking of "America's Best Hospitals" is an existing, popular hospital-profiling system, but it is unknown whether top-ranked hospitals in their report have better outcomes according to other hospital quality metrics such as the Centers for Medicare and Medicaid Services (CMS) publicly reported 30-day stroke measures...
November 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30413291/carotid-artery-related-perioperative-stroke-following-anterior-cervical-spine-surgery-a-series-of-3-cases-and-literature-review
#6
Yue-Qi Du, Wan-Ru Duan, Zan Chen, Hao Wu, Feng-Zeng Jian
BACKGROUND: Vascular complications following anterior cervical spine surgery are rare but potentially devastating. Complications associated with the carotid artery are even more disastrous but largely anecdotal, with no more than 4 reported cases. MATERIALS AND METHODS: We report 3 new cases of carotid artery-related perioperative stroke following anterior cervical spine surgery. All 3 patients had carotid artery atherosclerosis and the time of intraoperative carotid artery retraction was longer than 1 hour...
November 6, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30409747/patients-with-acute-lacunar-infarction-have-benefit-from-intravenous-thrombolysis
#7
Zeljko Zivanovic, Marina Gubi, Dmitar Vlahovic, Marija Milicevic, Mirjana Jovicevic, Aleksandra Lucic, Svetlana Ruzicka-Kaloci, Biljana Radovanovic, Tamara Rabi Zikic, Marija Zarkov, Nemanja Popovic, Petar Slankamenac
INTRODUCTION: Usefulness of intravenous thrombolysis in patients with acute lacunar cerebral infarction is questionable. The aim of this study was to evaluate the efficacy and safety of intravenous thrombolysis in patients with lacunar infarction in comparison with patients with nonlacunar infarction as well as with patients with lacunar infarction who were not treated with intravenous thrombolysis. MATERIALS AND METHODS: In the first part of the study, among patients with acute ischemic stroke treated with intravenous thrombolysis, characteristics and outcomes of 46 patients with lacunar and 221 patients with nonlacunar infarction were compared...
November 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30409746/persistent-primitive-olfactory-artery-as-novel-collateral-channel-to-the-anterior-cerebral-artery-in-moyamoya-disease
#8
Tetsuhiro Kamo, Haruto Uchino, Hisayasu Saito, Daina Kashiwazaki, Naoki Akioka, Naoya Kuwayama, Satoshi Kuroda
BACKGROUND: There are a variety of collateral routes to compensate persistent cerebral ischemia in moyamoya disease. However, there is no report presenting the persistent primitive olfactory artery (POA) as a spontaneous collateral route to the anterior cerebral artery (ACA) in moyamoya disease. METHODS: We precisely examined cerebral angiography in 84 patients with moyamoya disease to identify the collateral channel through the persistent POA. Its anatomy was evaluated on pre- and postoperative angiography...
November 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30409745/subcutaneous-heparin-therapy-for-patients-with-cancer-associated-stroke
#9
Hiroyuki Kawano, Yuko Honda, Tatsuo Amano, Haruko Okano, Rieko Suzuki, Masataka Torii, Yoshiko Unno, Yoshiaki Shiokawa, Teruyuki Hirano
BACKGROUND: Anticoagulation therapy, particularly subcutaneous heparin therapy, is recommended for cancer-associated thrombosis. However, not starting or discontinuing anticoagulation was not rare. The aim of the present study was to examine the practical issues related to anticoagulation therapy and effects of subcutaneous heparin therapy for cancer-associated stroke. METHODS: Patients with cancer-associated stroke in our stroke center between October 2014 and August 2017 who were diagnosed as having acute ischemic stroke based on diffusion-weighted imaging were retrospectively enrolled...
November 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30409744/angiotensinogen-m235t-gene-polymorphism-is-a-genetic-determinant-of-cerebrovascular-and-cardiopulmonary-morbidity-in-adolescents-with-sickle-cell-disease
#10
Mohsen Saleh ElAlfy, Fatma Soliman Elsayed Ebeid, Tarek Mostafa Kamal, Deena Samir Eissa, Eman Abdel Rahman Ismail, Samar Hassan Mohamed
BACKGROUND: Cerebrovascular stroke is a common critical complication of sickle cell disease (SCD). Angiotensinogen (AGT) M235T gene polymorphism is associated with risk of ischemic stroke and cardiovascular disease. AIM: We investigated the potential association between angiotensinogen M235T gene polymorphism and susceptibility to cerebrovascular and cardiopulmonary complications in adolescents with SCD. METHODS: Forty-six patients with SCD in steady state were studied stressing on history of stroke, hydroxyurea/chelation therapy, hematological profile, and echocardiographic findings...
November 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30409743/the-impact-of-covert-lacunar-infarcts-and-white-matter-hyperintensities-on-cognitive-and-motor-outcomes-after-stroke
#11
Angela M Auriat, Jennifer K Ferris, Sue Peters, Joel Ramirez, Sandra E Black, Claudia Jacova, Lara A Boyd
BACKGROUND AND AIMS: In addition to overt stroke lesions, co-occurring covert lesions, including white matter hyperintensities (WMH) and covert lacunar infarcts (CLI), contribute to poststroke outcome. The purpose of this study was to examine the relationship between covert lesions, and motor and cognitive outcomes in individuals with chronic stroke. METHODS: Volumetric quantification of clinically overt strokes, covert lesions (periventricular and deep: pWMH, dWMH, pCLI, dCLI), ventricular and sulcal CSF (vCSF, sCSF), and normal appearing white (NAWM) and gray matter (NAGM) was performed using structural magnetic resonance imaging...
November 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30401611/reduced-doses-of-direct-oral-anticoagulants-in-ischemic-stroke-patients-with-nonvalvular-atrial-fibrillation
#12
Ichiro Deguchi, Masaki Takao
BACKGROUND: The choice of standard or reduced doses of direct oral anticoagulants (DOACs) depends on patients' age, body weight, and renal function based on package instructions. Our aim was to conduct a simulation of DOAC dose using patients' data obtained on admission. METHODS: This retrospective study included 314 ischemic stroke patients with nonvalvular atrial fibrillation admitted to our hospital between September 2014 and February 2018. Data on age, body weight, creatinine, and creatinine clearance were collected for each subject, and simulation was conducted for the dose of each DOAC...
November 3, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30396840/vernet-s-syndrome-associated-with-internal-jugular-vein-thrombosis
#13
Myungah Lee, Youngjae Heo, Taewon Kim
Our objective is to present a case of Vernet's syndrome (cranial nerve (CN) IX, X, and XI palsy) associated with cerebral venous thrombosis (CVT) in an internal jugular vein. The patient presented with acutely developed dysphagia. The weakness of the left sternocleidomastoid and trapezius muscles was observed. The initial magnetic resonance imaging and computed tomography (CT) with contrast enhancement showed contrast-filling defect in the left internal jugular vein inside the jugular foramen. The magnetic resonance venography with contrast enhancement revealed a partial filling defect in the left sigmoid sinus and total occlusion of the left internal jugular vein...
November 2, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30396839/left-ventricular-ejection-fraction-and-clinically-defined-heart-failure-to-predict-90-day-functional-outcome-after-ischemic-stroke
#14
Yi Li, Timothy P Fitzgibbons, David D McManus, Richard P Goddeau, Brian Silver, Nils Henninger
BACKGROUND: Heart failure (HF) is a risk factor for atrial fibrillation (AF), stroke, and post-stroke disability. However, differing definitions and application of HF-criteria may impact model prediction. We compared the predictive ability of left ventricular ejection fraction (LVEF), a readily available objective echocardiographic index, with clinical HF definitions for functional disability and AF in stroke patients. METHODS: We retrospectively analyzed ischemic stroke patients evaluated between January 2013 and May 2015...
November 2, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30396838/residual-shunt-after-patent-foramen-ovale-device-closure-in-patients-with-cryptogenic-stroke-serial-bubble-contrast-transesophageal-echocardiography-data
#15
Jeonggeun Moon, Minsu Kim, Pyung Chun Oh, Dong Hoon Shin, Hyeon-Mi Park, Youn Yi Jo, Ji Sung Lee, Woong Chol Kang
BACKGROUND: Percutaneous closure of patent foramen ovale (PFO) is an alternative option to medical treatment for secondary prevention for cryptogenic stroke (CS). Despite technical success of procedure, residual shunt (RS) which is a presumable cause for recurrent stroke is observed in some patients. We evaluated the RS with serial follow-up bubble contrast transesophageal echocardiography (BCTEE) after PFO closure. METHODS: Among consecutive 47 CS patients who underwent PFO closure, a serial follow-up BCTEE at 3 and 9 months after the index procedure was completed in 38 patients (81%, 46 ± 10 years, 19 men)...
November 2, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30396837/early-magnetic-resonance-imaging-decreases-hospital-length-of-stay-in-patients-with-ischemic-stroke
#16
Bharti Manwani, Subhendu Rath, Nora S Lee, Ilene Staff, Christoph Stretz, Janhavi Modak, Pasquale F Finelli
BACKGROUND: Imaging modalities are important part of stroke evaluation. Noncontrast head computed tomography (CT) is the initial imaging modality in acute stroke and although important to rule out acute hemorrhage and making a decision on thrombolytic treatment, ischemic changes may not be visible on CT for up to 24 hours. Magnetic resonance imaging (MRI) brain is an invaluable tool to confirm an ischemic stroke and facilitates stroke evaluation. Objective of this study was to investigate the correlation between time to MRI and length of hospital stay...
November 2, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30392834/differential-expression-of-vascular-endothelial-growth-factor-a-165-isoforms-between-intracranial-atherosclerosis-and-moyamoya-disease
#17
Hao Jiang, Juan F Toscano, Michael Schiraldi, Shlee S Song, Konrad H Schlick, Oana M Dumitrascu, Raymond Liou, Patrick D Lyden, Jianwei Pan, Renya Zhan, Jeffrey L Saver, Nestor R Gonzalez
BACKGROUND: Vascular endothelial growth factor-A165 (VEGF-A165 ) has been identified as a combination of 2 alternative splice variants: proangiogenic VEGF-A165 a and antiangiogenic VEGF-A165 b. Intracranial atherosclerotic disease (ICAD) and moyamoya disease (MMD) are 2 main types of intracranial arterial steno-occlusive disorders with distinct capacities for collateral formation. Recent studies indicate that VEGF-A165 regulates collateral growth in ischemia. Therefore, we investigated if there is a distinctive composition of VEGF-A165 isoforms in ICAD and MMD...
November 1, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30392833/no-weekend-or-after-hours-effect-in-acute-ischemic-stroke-patients-treated-by-telemedicine
#18
T C Cossey, Amanda Jagolino, Christy Ankrom, Arvind B Bambhroliya, Chunyan Cai, Farhaan S Vahidy, Sean I Savitz, Tzu-Ching Wu
BACKGROUND: Stroke outcomes have been shown to be worse for patients presenting overnight and on weekends (after-hours) to stroke centers compared with those presenting during business hours (on-hours). Telemedicine (TM) helps provide evaluation and safe management of stroke patients. We compared time metrics and outcomes of stroke patients who were assessed and received intravenous recombinant tissue plasminogen activator (IV-tPA) via TM during after-hours with those during on-hours...
November 1, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30392832/neuroimaging-findings-in-intracranial-sarcoid-phlebitis-a-case-report
#19
Girish Bathla, Sudeepta Dandapat, Neetu Soni, Ravishankar P Maheshwarappa
INTRODUCTION: Venous phlebitis in Neurosarcoidosis (NS) is rare but is often associated with intracranial hemorrhage (ICH). Imaging findings in such cases have been recently described on susceptibility weighted imaging (SWI). CASE PRESENTATION AND OUTCOME: We report a patient who presented with ICH. Magnetic resonance imaging provided evidence for parenchymal and leptomeningeal involvement while SWI and vessel wall imaging (VWI) helped confirmed NS associated intracranial phlebitis...
November 1, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30392831/ischemic-stroke-due-to-virologically-confirmed-varicella-zoster-virus-vasculopathy-a-case-series
#20
Takao Hoshino, Sono Toi, Kunio Toda, Yumiko Uchiyama, Hiroshi Yoshizawa, Mutsumi Iijima, Yuko Shimizu, Kazuo Kitagawa
BACKGROUND: Limited data are available regarding the characteristics and prognosis of patients with stroke due to varicella zoster virus (VZV) vasculopathy. METHODS: We studied 4 patients (2 men and 2 women; age, 38-63 years) from a single center who developed acute ischemic stroke due to VZV vasculopathy. The virological diagnosis was confirmed by detecting VZV DNA and/or the IgG antibody to VZV in the cerebrospinal fluid. RESULTS: Three patients were taking immunosuppressive agents, including prednisolone and/or methotrexate, at baseline...
November 1, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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