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Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association

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https://www.readbyqxmd.com/read/30642667/clinical-impact-of-oral-anticoagulation-in-patients-with-atrial-high-rate-episodes
#1
Rita Marinheiro, Leonor Parreira, Pedro Amador, Cláudia Lopes, Andreia Fernandes, Dinis Mesquita, José Farinha, Marta Fonseca, Tatiana Duarte, Rui Caria
BACKGROUND: Atrial high-rate episodes (AHREs) are common in pacemaker patients. Our aims were to compare patients with AHREs to those without them and to assess if, in those with AHREs, the initiation of oral anticoagulation (OAC) has any clinical impact on the occurrence of ischemic and hemorrhagic events. METHODS: From 2014-2017 we selected patients with pacemaker in whom AHREs were detected. AHREs were defined as episodes lasting more than 6 minutes if the electrogram was available or more than 6 hours if not...
January 11, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30642666/metabolic-profile-for-prediction-of-ischemic-stroke-in-chinese-hypertensive-population
#2
Xiaofan Guo, Zhao Li, Ying Zhou, Shasha Yu, Hongmei Yang, Liqiang Zheng, Yamin Liu, Yingxian Sun
BACKGROUND: Stroke burden is extremely high in Chinese hypertensive population. Novel biomarkers for cardiovascular diseases can be detected by metabolomic profiling of human fluids. We aim to find a panel of distinctive plasma metabolites for predicting incident ischemic stroke in hypertensive patients. METHODS: This is a nested case-control study from a prospective cohort design. Baseline plasma samples were collected from 66 newly developed ischemic stroke cases and 66 matched controls...
January 11, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30642665/association-between-total-cholesterol-and-5-year-mortality-in-patients-with-carotid-artery-stenosis-and-poststroke-functional-dependence
#3
Yen-Ju Lung, Wei-Chieh Weng, Chia-Lun Wu, Wen-Yi Huang
BACKGROUND: Aggressive lipid-lowering treatment reduces the risk of cardiovascular events, but remains controversial in stroke patients. We investigate the influence of total cholesterol level on 5-year outcomes of ischemic stroke patients with high-grade internal carotid artery (ICA) stenosis and poststroke functional dependence. METHODS: One-hundred and ninety-six acute ischemic stroke patients with high-grade ICA stenosis and modified Rankin Scale score ≥ 3 upon discharge were enrolled and prospectively observed for 5 years...
January 11, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30639145/long-term-effect-of-promoting-in-hospital-physical-activity-on-postdischarge-patients-with-mild-ischemic-stroke
#4
Masashi Kanai, Kazuhiro P Izawa, Masafumi Nozoe, Hiroki Kubo, Miki Kobayashi, Akira Onishi, Kyoshi Mase, Shinichi Shimada
BACKGROUND: Although there are reports on the promotion of physical activity during hospitalization, there is no evidence that promoting in-hospital physical activity continues over time after discharge. The purpose of this study was to evaluate the long-term effect of promoting in-hospital physical activity on postdischarge physical activity and self-efficacy for physical activity in patients with mild ischemic stroke. METHODS: This was a cross-sectional study of a post hoc analysis of a previous randomized controlled trial...
January 10, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30639144/long-term-effects-on-preventing-stroke-after-endovascular-treatment-or-bypass-surgery-for-intracranial-arterial-stenosis
#5
Takuma Nakashima, Takao Kojima, Norikazu Hatano, Syuntaro Takasu, Yutaro Fuse, Yukio Seki
BACKGROUND: Intracranial arterial stenosis (ICAS) is an important cause of ischemic stroke worldwide due to its higher risk of recurrence with medical therapy. Although some large randomized studies failed to show the superiority of surgical treatment compared with medical therapy, the results of medical therapy are not sufficient. There are patients who still benefit from surgical treatment. This retrospective analysis aimed to evaluate the long-term efficacy of surgical therapy with percutaneous transluminal angioplasty and/or stenting (PTA/PTAS) or extracranial-intracranial (EC/IC) bypass surgery for patients with ICAS...
January 10, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638942/a-clinical-paradigm-for-classifying-neurologic-symptoms-to-screen-for-emergent-large-vessel-occlusions
#6
Rebecca Pollard, Michelle Leppert, Charles Rawson, Mitchell Boehnke, Justin Honce, Lidia Nagae, Sharon Poisson, Eric Nyberg
BACKGROUND: With newly-extended treatment windows for endovascular therapy in emergent large vessel occlusions, it is increasingly important to identify thrombectomy-eligible patients without overwhelming resources dedicated to acute stroke care. We devised a simple paradigm to classify patient's presenting neurologic symptoms to screen for large vessel occlusions. METHODS: We reviewed the presenting symptoms, imaging findings, and final diagnoses of consecutive emergency department stroke alert cases...
January 10, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638940/short-term-risk-of-ischemic-stroke-after-detection-of-left-ventricular-thrombus-on-cardiac-magnetic-resonance-imaging
#7
Alexander E Merkler, Javid Alakbarli, Gino Gialdini, Babak B Navi, Santosh B Murthy, Parag Goyal, Jiwon Kim, Richard B Devereux, Monika M Safford, Costantino Iadecola, Hooman Kamel, Jonathan W Weinsaft
BACKGROUND: The short-term risk of ischemic stroke in patients with left ventricular (LV) thrombus identified via delayed-enhancement cardiac magnetic resonance (DE-CMR) imaging is uncertain. METHODS: We performed a retrospective cohort study of patients who underwent DE-CMR for evaluation of LV systolic dysfunction at NewYork-Presbyterian Hospital/Weill Cornell between 2007 and 2016. We identified all hospitalized patients who had DE-CMR evidence of LV thrombus, and as controls, all hospitalized patients who had no DE-CMR evidence of LV thrombus; 2 control patients were randomly selected for each patient with LV thrombus...
January 10, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638944/internal-carotid-artery-occlusion-causing-acute-cranial-neuropathies
#8
Stephen R Duma, Samer Ghattas, Florence C F Chang
A 54-year-old male with a history of left posterior parietal ischemic stroke, epilepsy, tobacco and marijuana smoking, and alcohol abuse, presented with acute left visual loss and diplopia. On examination, he had reduced left visual acuity and a left oculomotor nerve palsy. CT angiogram from aortic arch to circle of Willis identified extensive thrombus occluding the left common and internal carotid arteries, extending to the left ophthalmic artery. This case demonstrates acute visual loss from ophthalmic artery occlusion, and left oculomotor nerve palsy from occlusion of the inferolateral trunk of the internal carotid artery (cavernous sinus portion)...
January 9, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638943/mortality-and-predictors-of-death-poststroke-data-from-a-multicenter-prospective-cohort-of-lebanese-stroke-patients
#9
Rachel Abdo, Halim Abboud, Pascale Salameh, Taghrid El Hajj, Hassan Hosseini
BACKGROUND: Despite efforts to reduce stroke mortality rates, the disease remains a leading cause of death in Lebanon highlighting the importance of understanding risk factors and subsequent mortality. We examined mortality rates during the first year after acute stroke and the major short-term (1-month) and long-term (1-year) mortality predictors. METHODS: Data were collected prospectively on hospitalized stroke patients from 8 hospitals in Beirut during a 1-year period...
January 9, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638941/stroke-mimics-and-accuracy-of-referrals-made-by-emergency-department-doctors-in-japan-for-patients-with-suspected-stroke
#10
Narushi Sugii, Alexander Zaboronok, Hiroyuki Fujimori, Naoaki Sato, Keishi Fujita, Eiichi Ishikawa, Akira Matsumura
BACKGROUND: Stroke mimics (SMs)are medical conditions that are at first considered to be of cerebrovascular etiology but turn out to be a condition other than stroke. While many reports on SMs have been published, there have been none from Japan. Thus, we sought to assess the current state of SMs in a Japanese population. METHODS: We collected data of patients referred with suspicion of stroke to neurosurgeons by emergency department (ED) doctors, and we retrospectively evaluated the diagnosis concordance rate between the ED doctors and the neurosurgeons...
January 9, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638939/microembolic-signals-is-associated-with-insulin-resistance-among-acute-ischemic-stroke-patients
#11
Xuyou Zhou, Dongmei Zhang, Yong Zhou, Fang Wang, Xiangyang Zhu
BACKGROUND: Microembolic signals (MES) and insulin resistance (IR) is common in patients with acute ischemic stroke (AIS). Patients with active MES tend to be more seriously ill and prone to aggravating disease progression. IR is an important risk factor for stroke which has been found to be associated with the severity of stroke. This study aims to investigate the clinical correlation between intracranial MES and IR in AIS patients. METHODS: A total of 119 patients with AIS were enrolled in this study...
January 9, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638938/reliability-of-the-acutely-estimated-premorbid-modified-rankin-scale-for-stroke-treatment-decision-making
#12
WenWen Zhang, Skye Coote, Tanya Frost, Helen M Dewey, Phillip M Choi
BACKGROUND: Premorbid functional status is an important factor in acute stroke treatment decision making. Determining the modified Rankin Score (mRS) accurately may be difficult due to deficits from stroke and lack of collateral information in the acute setting. Data on the reliability of the premorbid mRS in "real-world" practice outside of clinical trial or registry settings are limited. METHODS: A retrospective study at a high volume academic primary stroke center...
January 9, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638937/a-23-year-old-woman-with-sudden-onset-blindness-of-the-right-eye
#13
Yosuke Takeuchi, Keiichi Nakahara, Makoto Nakajima, Yasuteru Inoue, Riyo Matsumura, Munekage Yamaguchi, Hidetaka Katabuchi, Yukio Ando
A 23-year-woman was presented for sudden-onset monocular blindness. Branch retinal artery occlusion in the right eye and multiple brain embolism were detected. Trousseau syndrome due to bilateral ovarian cancer was diagnosed; no embolic events were observed after anticoagulant therapy and surgical resection.
January 8, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30638936/obsessive-compulsive-disorder-following-cerebrovascular-accident-a-case-report-and-literature-review
#14
Rie Akaho, Ichiro Deguchi, Hiroshi Kigawa, Katsuji Nishimura
BACKGROUND: Cases of obsessive-compulsive disorder (OCD) following cerebrovascular accident (CVA) have rarely been reported. METHODS: Case report and literature review. RESULTS: We describe the case of a 58-year-old, right-handed man developed OCD 17 months after stroke resulting from lesion of the right middle cerebral artery infarction. The patient was successfully treated with sertraline up to 50 mg per day. His OCD behaviors largely reduced in 6 weeks, and the Yale-Brown Obsessive Compulsive Scale score was reduced from 29 to 12 in 1 year...
January 8, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30635219/study-on-the-clinical-imaging-and-pathological-characteristics-of-18-cases-with-primary-central-nervous-system-vasculitis
#15
Lin-Jing Wang, De-Zheng Kong, Zhen-Ni Guo, Fu-Liang Zhang, Hong-Wei Zhou, Yi Yang
BACKGROUND: To summarize the characteristics of primary central nervous system vasculitis from clinical, imaging, and pathological aspects by retrospective study. METHODS: From March 2015 to December 2017, the data of the inpatients of primary central nervous system vasculitis in first Hospital of Jilin University were collected, and their clinical manifestation, imaging, and pathological characteristics were analyzed by using a descriptive method. RESULTS: There were 18 patients, 10 males (55...
January 8, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30635218/endovascular-treatment-of-cerebral-venous-sinus-thrombosis-and-insights-into-intracranial-coagulopathy
#16
David Roh, Jason Carroll, Kara Melmed, Mitchell S V Elkind, Andrew Eisenberger, Richard Francis, Soojin Park, Sachin Agarwal, Jan Claassen, Philip M Meyers
Cerebral venous sinus thrombosis (CVST) requires anticoagulation to promote vessel recanalization. Current anticoagulation paradigms utilize plasma tests from peripheral venous/arterial samples for therapeutic monitoring. We describe a medically-refractory case of CVST in a 35-year-old woman later found to have JAK2 mutation and essential thrombocytosis. Despite therapeutic anticoagulation levels, worsening cerebral edema and progression to coma prompted endovascular treatment. Failed endovascular thrombectomy attempts led to placement of 2 separate indwelling microcatheters for continuous infusion of tissue plasminogen activator (tPA)...
January 8, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30630757/right-in-comparison-to-left-cerebral-hemisphere-damage-by-stroke-induces-poorer-muscular-responses-to-stance-perturbation-regardless-of-visual-information
#17
Daniel Boari Coelho, Corina Aparecida Fernandes, Alessandra Rezende Martinelli, Luis Augusto Teixeira
OBJECTIVE: Fast and scaled muscular activation is required to recover body balance following an external perturbation. An issue open to investigation is the extent to which the cerebral hemisphere lesioned by stroke leads to asymmetric deficits in postural reactive responses. In this experiment, we aimed to compare muscular responses to unanticipated stance perturbations between individuals who suffered unilateral stroke either to the right or to the left cerebral hemisphere. METHODS: Stance perturbations were produced by releasing a load attached to the participant's trunk, inducing fast forward body oscillation...
January 8, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30630758/a-high-prevalence-of-intracranial-stenosis-in-patients-with-coronary-artery-disease-and-the-diagnostic-value-of-transcranial-duplex-sonography
#18
Jurgita Valaikiene, Ligita Ryliskyte, Arunas Valaika, Roma Puronaite, Jurate Dementaviciene, Arunas Vaitkevicius, Jolita Badariene, Irena Butkuviene, Gintaras Kalinauskas, Aleksandras Laucevicius
BACKGROUND: According to the data from the population-based Rotterdam study, intracranial carotid artery calcification detected by computed tomography is very common and contributed to 75% of all strokes. The aim of the present study was to estimate the prevalence of intracranial stenosis (IS) using noninvasive transcranial color-coded duplex sonography (TCCS) in neurologically asymptomatic patients with coronary artery disease (CAD). METHODS: Three hundred and eighty-nine patients with angiographically-confirmed, severe CAD were included prospectively...
January 7, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30630756/reversible-cerebral-vasoconstriction-syndrome-after-administering-etanercept-during-puerperium
#19
Daisuke Hara, Saki Nukui, Takahiro Shimizu, Hisanao Akiyama, Yasuhiro Hasegawa
Our objective is to clarify relationship between reversible cerebral vasoconstriction syndrome and administrating etanercept during puerperium. Several lines of evidence have suggested tumor necrosis factor (TNF) as a mediator of vascular dysfunction associated with estrogen deficiency. A 32-year-old woman resumed etanercept (25 mg/week), a TNF inhibitor, which had been discontinued during pregnancy, because of the deterioration of rheumatoid arthritis. She was admitted to our hospital with upper right quadrant blindness and mild right hemiparesis accompanied by pulsating left occipital pain, which had appeared 4 hours after restarting etanercept (25 mg/week)...
January 7, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30630755/influence-of-platelet-aggregate-formation-in-blood-samples-on-light-transmission-aggregometry-results
#20
Eriko Sugawara, Mie Shimizu, Masahiro Yamamoto, Yosuke Kudo, Fumiaki Tanaka, Ken Johkura
BACKGROUND: Light transmission aggregometry is a standard method used to evaluate platelet function. However, in clinical settings, light transmission aggregometry results sometimes fail to reflect actual platelet hyperactivity. In patients with suspected platelet hyperactivity such as thrombosis, platelet aggregates are frequently detected in citrated blood samples using a scattergram of a hematology analyzer. This study aimed to evaluate the effects of platelet aggregate formation on light transmission aggregometry results...
January 7, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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