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Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association

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https://www.readbyqxmd.com/read/30017747/safety-of-recanalization-therapy-in-patients-with-acute-ischemic-stroke-under-anticoagulation-a-systematic-review-and-meta-analysis
#1
REVIEW
Mingsu Liu, Yang Zheng, Guangqin Li
BACKGROUND: Intravenous thrombolysis treatment (IVT) and endovascular therapy (EVT) have been proved as fist-line beneficial option for eligible patients who have acute ischemic stroke (AIS) with major safety concern of symptomatic intracranial hemorrhage (sICH). Unfortunately, the emergency management of patients with AIS taking vitamin K antagonists and with international normalized ratio higher than 1.7 or taking new oral anticoagulants (NOACs) represents a great challenge. We aim to comprehensively determine the safety of EVT in patients under prior-stroke anticoagulants and IVT in patients under NOAC use...
July 12, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29983229/the-importance-of-the-full-blood-count-in-cerebral-ischemia-a-review-of-609-consecutive-young-patients-with-stroke-and-transient-ischemic-attacks
#2
Alice Taylor, Vafa Alakbarzade, Arvind Chandratheva, Robert Simister, Marie Scully
BACKGROUND: Almost half of ischemic strokes in young individuals are cryptogenic. Thrombophilia testing is routinely sent despite limited evidence linking to arterial cerebrovascular events. A full blood count may identify underlying hematological disorder. METHODS: We retrospectively reviewed all patients younger than 60 years with stroke and transient ischemic attack (TIA) presenting to a regional hyperacute stroke unit and daily TIA clinic from January 2015 to August 2016...
July 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29970322/comparison-of-premortem-magnetic-resonance-imaging-and-postmortem-autopsy-findings-of-a-cortical-microinfarct
#3
Hidehiro Ishikawa, Yuichiro Ii, Atsushi Niwa, Akihiro Shindo, Ai Ito, Keita Matsuura, Ryogen Sasaki, Kenichiro Uno, Masayuki Maeda, Hidekazu Tomimoto
An 85-year-old woman diagnosed with amyotrophic lateral sclerosis died of pneumonia and was autopsied. Magnetic resonance imaging (MRI) performed 16days before death revealed an intracortical high-intensity lesion in her right temporal cortex on three-dimensional (3D)-double inversion recovery (DIR) and 3D-fluid-attenuated inversion recovery (FLAIR) images. Histopathological examination indicated a cortical microinfarct (CMI) juxtaposed to cerebral amyloid angiopathy. Recently, in vivo detection of CMIs using 3D-DIR and 3D-FLAIR on 3-tesla MRI has been reported, and postmortem MRI study confirmed the presence of CMIs...
July 1, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29970323/modern-interdisciplinary-and-interhospital-acute-stroke-therapy-what-patients-think-about-it-and-what-they-really-understand
#4
Hannah Pressler, Arno Reich, Jörg Bernhard Schulz, Omid Nikoubashman, Klaus Willmes, Pardes Habib, Jan-Philipp Bach
BACKGROUND: Access to reperfusion therapies in patients with large vessel occluding acute ischemic stroke demands process reorganization and optimization. Neurovascular networks are being built up to provide 24/7 endovascular stroke therapy service. In times of an increasingly complex stroke rescue chain little is known about patients' and their relatives' treatment awareness. METHODS: All patients, who received any kind of acute reperfusion treatment between January and August 2017 in the university hospital Aachen, and their proxies, were included in the survey...
June 30, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29970321/selection-of-oral-anticoagulants-in-ischemic-stroke-patients-with-nonvalvular-atrial-fibrillation
#5
Ichiro Deguchi, Norio Tanahashi, Masaki Takao
BACKGROUND: Anticoagulant therapy is indicated for management of ischemic stroke patients with nonvalvular atrial fibrillation. We retrospectively investigated how oral anticoagulants were selected for ischemic stroke patients with nonvalvular atrial fibrillation. METHODS: This study included 297 stroke patients with nonvalvular atrial fibrillation admitted to our hospital between September 2014 and December 2017, and who were subsequently transferred to other institutions or discharged home...
June 30, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29960667/homocysteine-is-associated-with-exaggerated-morning-blood-pressure-surge-in-patients-with-acute-ischemic-stroke
#6
Jun-Chao Xie, Ying-Ying Lin, Xiao-Hui Liu, Yi-Chen Zhao, Xiao-Ye Ma, Jia Yu, Xue-Yuan Liu, Yan-Xin Zhao
BACKGROUND: Considerable researches suggest that high level of homocysteine (Hcy) is associated with the risk of ischemic stroke. Ambulatory blood pressure monitoring (ABPM) parameters have also been confirmed associated with cardio-cerebrovascular events. However, the relationship between Hcy and ABPM parameters remains unclear in patients with acute ischemic stroke. In this study, we aim to investigate the association between Hcy level and ABPM parameters in patients with acute ischemic stroke...
June 27, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29960666/mechanical-thrombectomy-emerging-technologies-and-techniques
#7
REVIEW
Edgar A Samaniego, Jorge A Roa, Kaustubh Limaye, Harold P Adams
BACKGROUND: The treatment of acute ischemic stroke due to large vessel occlusion (LVO) has revolutionized in the last decade. We sought to compile the most relevant literature published about the evolution in treating this disabling and fatal disease. METHODS: A literature review of recent studies describing early treatment options like intravenous tissue plasminogen activator to the latest mechanical thrombectomy (MT) techniques was performed. We described in a chronological order the evolution of LVO treatment...
June 27, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29958849/the-nag-scale-noble-predictive-scale-for-hematoma-expansion-in-intracerebral-hemorrhage
#8
Kenichi Sakuta, Takeo Sato, Teppei Komatsu, Kenichiro Sakai, Yuka Terasawa, Hidetaka Mitsumura, Yasuyuki Iguchi
BACKGROUND AND PURPOSE: Early hematoma expansion (HE) is not rare in intracerebral hemorrhage (ICH) patients, but detecting those patients with high risk of HE is challenging. The aim of this retrospective study was to investigate the factors associated with HE in acute ICH patients, and to develop a simple predictive scale for HE. METHODS: We retrospectively reviewed consecutive patients with primary ICH, who received an initial non-contrast computed tomography (CT) scan within 24hours from symptom onset...
June 26, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29958848/endovascular-treatment-of-acute-basilar-artery-occlusion-registro-endovascolare-lombardo-occlusione-basilar-artery-reloba-study-group-experience
#9
Andrea Giorgianni, Francesco Biraschi, Mariangela Piano, Dikran Mardighian, Roberto Gasparotti, Michele Frigerio, Guglielmo Pero, Luca Quilici, Mario Crispino, Carlo Pellegrino, Marco Pavia, Roberto Peroni, Marco Longoni, Martino Cellerini, Elvis Lafe, Paolo Remida, Giuseppe Faragò, Paolo Reganati, Sabina Strocchi, Luca Valvassori
BACKGROUND: Acute basilar artery occlusion (BAO) is considered among the most severe medical emergencies, with very high morbidity and mortality. The aims of this study are to present 5 years experience of 12 centers in Lombardy region on BAO endovascular treatment and to evaluate prognostic factors that may improve clinical outcomes and recanalization rates. MATERIALS AND METHODS: Registro Endovascolare Lombardo Occlusione Basilar Artery (RELOBA) registry is a retrospective multicentric collection of patients with acute BAO who underwent endovascular treatment between 2010 and 2015...
June 26, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29945767/racial-difference-in-cerebral-microbleed-burden-among-a-patient-population-in-the-mid-south-united-states
#10
Nariman Noorbakhsh-Sabet, Georgios Tsivgoulis, Shima Shahjouei, Yirui Hu, Nitin Goyal, Andrei V Alexandrov, Ramin Zand
BACKGROUND: Although intracerebral hemorrhage (ICH) is more common among African-Americans, data on the burden of cerebral microbleeds (CMBs) among different races is limited. The purpose of this study is to compare the number, associated factors, and topography of CMBs between African-American and Caucasian populations in the Mid-South United States. METHODS: Using natural language processing, we extracted all brain MRIs performed during a 2-year period (2012-2013) when the report indicated the presence of CMB...
June 23, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29945766/secondary-stroke-prophylaxis-with-clopidogrel-produces-sufficient-antiplatelet-response
#11
Charlotte Lützhøft Rath, Niklas Rye Jørgensen, Troels Wienecke
BACKGROUND: Antiplatelet therapy is a cornerstone prevention strategy for secondary ischemic stroke (IS) and transient ischemic attack (TIA). Yet, a proportion of patients who receive antiplatelet therapy experience recurrent ischemic cerebrovascular events. A recent meta-analysis found an increased risk of recurrent stroke in clopidogrel- or aspirin-treated patients with ischemic stroke who had high on-treatment platelet reactivity (HTPR). Few studies have focused specifically on clopidogrel HTPR...
June 23, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29941394/the-jaguar-score-predicts-1-month-disability-death-in-ischemic-stroke-patient-ineligible-for-recanalization-therapy
#12
Aryandhito Widhi Nugroho, Hisatomi Arima, Naoyuki Takashima, Takako Fujii, Satoshi Shitara, Naomi Miyamatsu, Yoshihisa Sugimoto, Satoru Nagata, Masaru Komori, Yoshikuni Kita, Katsuyuki Miura, Kazuhiko Nozaki
BACKGROUND AND PURPOSE: Most available scoring system to predict outcome after acute ischemic stroke (AIS) were established in Western countries. We aimed to develop a simple prediction score of 1-month severe disability/death after onset in AIS patients ineligible for recanalization therapy based on readily and widely obtainable on-admission clinical, laboratory and radiological examinations in Asian developing countries. METHODS: Using the Shiga Stroke Registry, a large population-based registry in Japan, multivariable logistic regression analysis was conducted in 1617 AIS patients ineligible for recanalization therapy to yield ß-coefficients of significant predictors of 1-month modified Rankin Scale score of 5-6, which were then multiplied by a specific constant and rounded to nearest integer to develop 0-10 points system...
June 22, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29941393/association-of-urinary-incontinence-with-cognition-transfers-and-discharge-destination-in-acute-stroke-inpatient-rehabilitation
#13
David S Kushner, Doug Johnson-Greene
BACKGROUND: Acute-stroke prognostic indicators remain controversial including relationship of urinary incontinence with outcomes in cognition, transfers, and discharge destination. OBJECTIVE: To examine if urinary incontinence is associated with inpatient-rehabilitation (IR) outcomes in cognition, transfers, and discharge destinations. DESIGN: Retrospective observational study of 303 of 579(52%) acute-stroke patients admitted to IR 2012-2015 with complete urinary incontinence (total assistance for bladder management)...
June 22, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29941392/influence-of-contralateral-carotid-occlusion-on-outcomes-after-carotid-endarterectomy-a-meta-analysis
#14
Wenlong Cheng, Huijun Lu, Yali Hu
BACKGROUND: There is a controversy about whether the contralateral carotid occlusion (CO) in patients undergoing carotid endarterectomy (CEA) is associated with worse early and long-term outcomes. The aim of this systematic review and meta-analysis was to investigate the impact of CO on outcomes after CEA. METHODS: PubMed, Embase, and MEDLINE databases were searched until January 2018 for studies comparing early and long-term outcomes of CEA in patients with CO and with patent contralateral carotid (CP)...
June 22, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29934138/arterial-stiffness-is-independently-associated-with-severity-of-carotid-siphon-calcifications-in-community-dwelling-older-adults-the-atahualpa-project
#15
Oscar H Del Brutto, Robertino M Mera, Aldo F Costa, Ernesto Peñaherrera, Rubén Peñaherrera, Mauricio Zambrano
BACKGROUND: Knowledge on the association between arterial stiffness and intracranial atherosclerosis is limited. Here, we aimed to assess whether the aortic pulse wave velocity (PWV)-used as a surrogate of arterial stiffness-might independently predict severity of carotid siphon calcifications (CSCs), used as a marker of atherosclerosis. METHODS: Of 437 Atahualpa residents aged 60 years or older, 300 (69%) underwent head computed tomography (CT) (for CSC assessment), brain magnetic resonance imaging (for identification of neuroimaging signatures of cerebral small vessel disease [SVD]), and aortic PWV determinations (for arterial stiffness estimation)...
June 19, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29914759/coil-embolization-through-collateral-pathway-for-ruptured-vertebral-artery-dissecting-aneurysm-with-bilateral-vertebral-artery-occlusion
#16
Satoshi Murai, Kenji Sugiu, Tomohito Hishikawa, Masafumi Hiramatsu, Shingo Nishihiro, Naoya Kidani, Yu Takahashi, Isao Date
No abstract text is available yet for this article.
June 15, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29884521/nonaneurysmal-pseudo-subarachnoid-hemorrhage-computed-tomography-patterns-challenges-in-an-acute-decision-making-heuristics
#17
Tasneem F Hasan, Walter Duarte, Oluwaseun O Akinduro, Eric D Goldstein, Rebecca Hurst, Neil Haranhalli, David A Miller, Robert E Wharen, Rabih G Tawk, William D Freeman
BACKGROUND: Acute aneurysmal subarachnoid hemorrhage (SAH) is a medical and neurosurgical emergency from ruptured brain aneurysm. Aneurysmal SAH is identified on brain computed tomography (CT) as increased density of basal cisterns and subarachnoid spaces from acute blood products. Aneurysmal SAH-like pattern on CT appears as an optical illusion effect of hypodense brain parenchyma and/or hyperdense surrounding cerebral cisterns and blood vessels termed as "pseudo-subarachnoid hemorrhage" (pseudo-SAH)...
June 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29880211/tele-rehabilitation-after-stroke-an-updated-systematic-review-of-the-literature
#18
REVIEW
Fred S Sarfo, Uladzislau Ulasavets, Ohene K Opare-Sem, Bruce Ovbiagele
BACKGROUND: Tele-rehabilitation for stroke survivors has emerged as a promising intervention for remotely supervised administration of physical, occupational, speech, and other forms of therapies aimed at improving motor, cognitive, and neuropsychiatric deficits from stroke. OBJECTIVE: We aimed to provide an updated systematic review on the efficacy of tele-rehabilitation interventions for recovery from motor, higher cortical dysfunction, and poststroke depression among stroke survivors...
June 4, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29880210/new-prediction-score-for-hematoma-expansion-and-neurological-deterioration-after-spontaneous-intracerebral-hemorrhage-a-hospital-based-retrospective-cohort-study
#19
Makiko Miyahara, Ryuichi Noda, Shoji Yamaguchi, Yuta Tamai, Masato Inoue, Kouichiro Okamoto, Tetsuo Hara
OBJECTIVE: To ensure hematoma expansion and neurological deterioration in the management of acute spontaneous intracerebral hemorrhage, accurate prediction is crucial for initial assessment on admission. We conducted this study to develop a new clinical prediction score using only noncontrast computed tomography image and simply measurable variables. METHODS: This study was a retrospective cohort analysis. The study took place in a single academic medical center in Japan...
June 4, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29861129/infratentorial-cerebral-microbleeds-in-patients-with-cerebral-amyloid-angiopathy
#20
Dimitri Renard, Lavinia Tatu, Eric Thouvenot
BACKGROUND: Cerebral microbleeds (CMBs) observed in hypertension-related arteriolosclerosis tend to occur in the supratentorial deep gray matter, whereas those in cerebral amyloid angiopathy (CAA) typically show a supratentorial lobar distribution. Recently, superficial spontaneous cerebellar intracerebral hemorrhage has been shown to be associated with strictly lobar CMBs. Few data exist on infratentorial CMBs in CAA. The purpose of this study was to describe the incidence, number, and characteristics of infratentorial CMBs in patients with CAA...
May 31, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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