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Nutrition, Metabolism, and Cardiovascular Diseases: NMCD

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https://www.readbyqxmd.com/read/29289573/relationship-between-spicy-flavor-spicy-food-intake-frequency-and-general-obesity-in-a-rural-adult-chinese-population-the-ruraldiab-study
#1
K Yang, Y Li, Z Mao, X Liu, H Zhang, R Liu, Y Xue, R Tu, X Liu, X Zhang, W Li, C Wang
BACKGROUND AND AIMS: The purpose of this study was to explore the association between spicy flavor, spicy food frequency, and general obesity in Chinese rural adults. METHODS AND RESULTS: A total of 15,683 subjects (5907 males, 9776 females) aged 35-74 years from the RuralDiab Study were recruited for this cross-sectional study. Analysis of covariance was used to determine the differences of participant characteristics across body mass index (BMI) categories. Logistic regression yielded adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for obesity associated with the level of spicy flavor and frequency of spicy food intake...
December 27, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29331539/serum-vitamin-d-deficiency-and-risk-of-hospitalization-for-heart-failure-prospective-results-from-the-moli-sani-study
#2
S Costanzo, A De Curtis, A Di Castelnuovo, M Persichillo, M Bonaccio, G Pounis, C Cerletti, M B Donati, G de Gaetano, L Iacoviello
BACKGROUND AND AIMS: Evidence indicates that Vitamin D deficiency may be associated with increased risk of cardiovascular disease, although findings on risk of heart failure (HF) are controversial. We investigated the relationship between serum Vitamin D and the incidence of hospitalization for HF in a large prospective cohort of Italian adults. METHODS AND RESULTS: 19,092 (49% men, age range 35-99 years) HF-free individuals from the Moli-sani study, with complete data on serum Vitamin D (25-hydroxyvitamin) levels and incident hospitalized HF, were analysed...
December 7, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29307660/vitamin-d-receptor-activation-by-paricalcitol-and-insulin-resistance-in-ckd
#3
B Spoto, P Pizzini, S Cutrupi, G Tripepi, G Curatola, F Mallamaci, C Zoccali
BACKGROUND AND AIMS: The nature of the link (causal vs non-causal) between low 1,25-OH vitamin D and insulin resistance (IR) in patients with chronic kidney disease (CKD) remains elusive. We have now made a post hoc analysis of the effect of vitamin D receptor activation by paricalcitol on IR in the complete dataset of a double-blind, randomized, placebo controlled trial, the Paricalcitol and ENdothelial fuNction in chronic kidneY disease (PENNY). METHODS AND RESULTS: Eighty-eight patients with stage 3-4 CKD were randomized (1:1) to receive 2 μg/day paricalcitol or matching placebo for 12 weeks...
December 7, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29331538/differential-lipid-metabolism-outcomes-associated-with-adrb2-gene-polymorphisms-in-response-to-two-dietary-interventions-in-overweight-obese-subjects
#4
O Ramos-Lopez, J I Riezu-Boj, F I Milagro, L Goni, M Cuervo, J A Martinez
BACKGROUND AND AIMS: A precise nutrigenetic management of hypercholesterolemia involves the understanding of the interactions between the individual's genotype and dietary intake. The aim of this study was to analyze the response to two dietary energy-restricted interventions on cholesterol changes in carriers of two ADRB2 polymorphisms. METHODS AND RESULTS: A 4-month nutritional intervention was conducted involving two different hypo-energetic diets based on low-fat (LF) and moderately high-protein (MHP) dietary patterns...
December 5, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29289574/long-term-clinical-impact-of-serum-albumin-in-coronary-artery-disease-patients-with-preserved-renal-function
#5
H Wada, T Dohi, K Miyauchi, J Shitara, H Endo, S Doi, H Konishi, R Naito, S Tsuboi, M Ogita, T Kasai, A Hassan, S Okazaki, K Isoda, S Suwa, H Daida
BACKGROUND AND AIMS: Low serum albumin level is reportedly associated with worse clinical outcomes in patients with chronic kidney disease (CKD). However, associations between decreased serum albumin level and outcomes in non-CKD patients with coronary artery disease (CAD) remain unclear. Therefore, we aimed to evaluate the prognostic value of serum albumin concentrations in stable CAD patients with preserved renal function. METHODS AND RESULTS: We studied 1316 patients with CAD and preserved renal function (estimated glomerular filtration rate ≥60 mL/min/1...
November 26, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29289572/comment-on-diabetes-remission-after-bariatric-surgery-is-characterized-by-high-glycemic-variability-and-high-oxidative-stress
#6
LETTER
A Bonaventura, F Montecucco
No abstract text is available yet for this article.
November 22, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29288010/molecular-analysis-of-three-known-and-one-novel-lpl-variants-in-patients-with-type-i-hyperlipoproteinemia
#7
A Caddeo, R M Mancina, C Pirazzi, C Russo, K Sasidharan, J Sandstedt, S Maurotti, T Montalcini, A Pujia, T P Leren, S Romeo, P Pingitore
BACKGROUND AND AIMS: Type I hyperlipoproteinemia, also known as familial chylomicronemia syndrome (FCS), is a rare autosomal recessive disorder caused by variants in LPL, APOC2, APOA5, LMF1 or GPIHBP1 genes. The aim of this study was to identify novel variants in the LPL gene causing lipoprotein lipase deficiency and to understand the molecular mechanisms. METHODS AND RESULTS: A total of 3 individuals with severe hypertriglyceridemia and recurrent pancreatitis were selected from the Lipid Clinic at Sahlgrenska University Hospital and LPL was sequenced...
November 22, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29170059/the-clinical-potential-of-adipogenesis-and-obesity-related-micrornas
#8
REVIEW
M Zaiou, H El Amri, A Bakillah
Obesity is a growing health problem commonly associated with numerous metabolic disorders including type 2 diabetes, hypertension, cardiovascular disease, and some forms of cancer. The burden of obesity and associated cardiometabolic diseases are believed to arise through complex interplay between genetics and epigenetics predisposition, nutrition, environment, and lifestyle. However, the molecular basis and the repertoire of obesity-affecting factors are still unknown. Emerging evidence is connecting microRNAs (miRNAs) dysregulation with adipogenesis and obesity...
November 20, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29167060/aging-process-adherence-to-mediterranean-diet-and-nutritional-status-in-a-large-cohort-of-nonagenarians-effects-on-endothelial-progenitor-cells
#9
F Cesari, F Sofi, R Molino Lova, F Vannetti, G Pasquini, F Cecchi, R Marcucci, A M Gori, C Macchi
BACKGROUND AND AIM: Adherence to the Mediterranean Diet (MD) has been associated with a longer and better life. The aim of this study was to examine the effects of adherence to the MD, and of nutritional habits on endothelial progenitor (EPCs) and circulating progenitor (CPCs) cells in a cohort of nonagenarians enrolled within the Mugello Study, an epidemiological study aimed at investigating both clinically relevant geriatric items and various health issues, including those related to nutritional status...
November 20, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29329924/effects-of-dark-chocolate-on-endothelial-function-in-patients-with-non-alcoholic-steatohepatitis
#10
L Loffredo, F Baratta, P Ludovica, S Battaglia, R Carnevale, C Nocella, M Novo, G Pannitteri, F Ceci, F Angelico, F Violi, M Del Ben
BACKGROUND AND AIM: Oxidative stress plays a pivotal role in inducing endothelial dysfunction and progression from simple fatty liver steatosis (FLD) to non-alcoholic steatohepatitis (NASH). Polyphenols could reduce oxidative stress and restore endothelial function by inhibiting the nicotinamide-adenine-dinucleotide-phosphate (NADPH) oxidase isoform Nox2. The aim of this study was to assess endothelial function and oxidative stress in a population affected by simple FLD and NASH. Furthermore, we analysed the effect of high vs low content of cocoa polyphenols on endothelial function and oxidative stress in patients with NASH...
November 13, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29310971/the-relationship-of-health-food-literacy-and-salt-awareness-to-daily-sodium-and-potassium-intake-among-a-workplace-population-in-switzerland
#11
X Luta, S Hayoz, C Gréa Krause, K Sommerhalder, E Roos, P Strazzullo, S Beer-Borst
BACKGROUND AND AIMS: High sodium (Na) and low potassium (K) intake are associated with hypertension and CVD risk. This study explored the associations of health literacy (HL), food literacy (FL), and salt awareness with salt intake, K intake, and Na/K ratio in a workplace intervention trial in Switzerland. METHODS AND RESULTS: The study acquired baseline data from 141 individuals, mean age 44.6 years. Na and K intake were estimated from a single 24-h urine collection...
November 13, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29258716/freestyle-libre-and-dexcom-g4-platinum-sensors-accuracy-comparisons-during-two-weeks-of-home-use-and-use-during-experimentally-induced-glucose-excursions
#12
F Boscari, S Galasso, A Facchinetti, M C Marescotti, V Vallone, A M L Amato, A Avogaro, D Bruttomesso
BACKGROUND AND AIMS: This study compared the accuracy of the FreeStyle Libre (Abbott, Alameda, CA) and Dexcom G4 Platinum (DG4P, Dexcom, San Diego, CA) CGM sensors. METHODS AND RESULTS: Twenty-two adults with type 1 diabetes wore the two sensors simultaneously for 2 weeks. Libre was used according to manufacturer-specified lifetime (MSL); DG4P was used 7 days beyond MSL. At a clinical research center (CRC), subjects were randomized to receive the same breakfast with standard insulin bolus (standard) or a delayed and increased (delayed & increased) bolus to induce large glucose swings during weeks 1 and 2; venous glucose was checked every 5-15 min for 6 h...
November 11, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29237548/dietary-patterns-and-the-risk-of-coronary-heart-disease-among-jordanians-a-case-control-study
#13
R F Tayyem, A E Al-Shudifat, A Johannessen, H A Bawadi, S S AbuMweis, L M Agraib, S S Allhedan, I Haj-Husein, M Azab
BACKGROUND AND AIMS: Dietary pattern and lifestyle have been reported to be significant risk factors in the development of coronary heart diseases (CHD). The contribution degree of these dietary risk factors in CHD development in non-westernized countries is unclear. This study aimed to evaluate several dietary choices and their potential association with CHD. METHODS AND RESULTS: A case-control study was conducted at Prince Hamza Hospital, a referral center for coronary angiography in Amman, Jordan...
November 8, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29241668/neutrophil-to-lymphocyte-ratio-is-a-strong-predictor-of-atherosclerotic-carotid-plaques-in-older-adults
#14
T Corriere, S Di Marca, E Cataudella, A Pulvirenti, S Alaimo, B Stancanelli, L Malatino
BACKGROUND AND AIMS: The Neutrophil-to-Lymphocyte Ratio (NLR), an index of systemic inflammation, has been reported to be associated with subclinical atherosclerosis, but its predictive role of the presence of carotid atherosclerotic plaques remains undefined. This study aims to assess this association which gives additional value to this biomarker, with respect to the main risk factors, in the prediction of carotid atherosclerosis in older adults. METHODS AND RESULTS: We recruited 324 patients, aged ≥65 years, without hematopoietic disorders, and/or history of malignancies, evidence of acute infections, chronic inflammatory status, and history of glucocorticoid therapy within the past three months, hospitalized in the Unit of Internal Medicine, University of Catania, Catania, Italy from January 2014 to December 2016...
November 5, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29329923/different-protein-composition-of-low-calorie-diet-differently-impacts-adipokine-profile-irrespective-of-weight-loss-in-overweight-and-obese-women
#15
R Mateo-Gallego, I Lamiquiz-Moneo, S Perez-Calahorra, V Marco-Benedí, A M Bea, L Baila-Rueda, M Laclaustra, J L Peñalvo, F Civeira, A Cenarro
BACKGROUND AND AIMS: High-protein (HP) diets have shown benefits in cardiometabolic markers such as insulin or triglycerides but the responsible mechanisms are not known. We aimed to assess the effect of three energy-restricted diets with different protein contents (20%, 27%, and 35%; ∼80% coming from animal source) on plasma adipokine concentration and its association with changes in cardiometabolic markers. METHODS: Seventy-six women (BMI 32.8 ± 2.93) were randomized to one of three calorie-reduced diets, with protein, 20%, 27%, or 35%; carbohydrates, 50%, 43%, or 35%; and fat, 30%, for 3 months...
November 4, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29174030/position-paper-on-vegetarian-diets-from-the-working-group-of-the-italian-society-of-human-nutrition
#16
C Agnoli, L Baroni, I Bertini, S Ciappellano, A Fabbri, M Papa, N Pellegrini, R Sbarbati, M L Scarino, V Siani, S Sieri
BACKGROUND: Interest in vegetarian diets is growing in Italy and elsewhere, as government agencies and health/nutrition organizations are emphasizing that regular consumption of plant foods may provide health benefits and help prevent certain diseases. METHODS AND RESULTS: We conducted a Pubmed search, up to September, 2015, for studies on key nutrients (proteins, vitamin B12, iron, zinc, calcium, vitamin D, and n-3 fatty acids) in vegetarian diets. From 295 eligible publications the following emerged: Vegetarians should be encouraged to supplement their diets with a reliable source of vitamin B12 (vitamin-fortified foods or supplements)...
October 31, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29241667/correlates-of-ideal-cardiovascular-health-in-european-adolescents-the-helena-study
#17
P Henriksson, H Henriksson, I Labayen, I Huybrechts, L Gracia-Marco, F B Ortega, V España-Romero, Y Manios, M González-Gross, A Marcos, L A Moreno, Á Gutiérrez, J R Ruiz
BACKGROUND AND AIMS: The ideal cardiovascular health (iCVH) construct consists of 4 health behaviors (smoking status, body mass index, physical activity and diet) and 3 health factors (total cholesterol, blood pressure and fasting glucose). A greater number of iCVH components in adolescence are related to better cardiovascular health, but little is known about the correlates of iCVH in adolescents. Thus, the aim of the study was to examine correlates of iCVH in European adolescents. METHODS AND RESULTS: The study comprised 637 European adolescents with complete iCVH data...
October 28, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29191476/the-association-between-serum-uric-acid-and-asymptomatic-intracranial-arterial-stenosis-in-middle-aged-koreans
#18
J K Ahn, J Hwang, J H Hwang, W T Yoon, P W Chung, S Ryu
BACKGROUND AND AIMS: Intracranial arterial stenosis (ICAS) is one of the most common causes of stroke, especially in Asians. Hyperuricemia has been associated with an increased risk of comorbidities such as metabolic syndrome or cardiovascular diseases. However, there are few studies focusing on the association between serum uric acid (SUA) levels and asymptomatic ICAS. The aim of this study was to explore the association between SUA and the prevalence of ICAS in middle-aged Korean health screening examinees...
October 27, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29174219/familial-diabetes-of-adulthood-a-bin-of-ignorance-that-needs-to-be-addressed
#19
S Prudente, O Ludovico, V Trischitta
AIMS: The aim of this article was to share with a wide readership some data and related reasoning about a multigenerational form of diabetes mellitus of adulthood. DATA SYNTHESIS: We have recently described a familial form of diabetes mellitus, which in the routine clinical setting of adult individuals is simplistically diagnosed as type 2 diabetes. Such misdiagnosis involves as much as 3% of adult unrelated diabetic patients with no evidence of autoimmune disease...
October 26, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29239740/hyperthyroxinemia-is-positively-associated-with-prevalent-and-incident-type-2-diabetes-mellitus-in-two-population-based-samples-from-northeast-germany-and-denmark
#20
T Ittermann, S Schipf, M Dörr, B H Thuesen, T Jørgensen, H Völzke, M R P Markus
BACKGROUND AND AIMS: A potential causal relationship between thyroid function and type 2 diabetes mellitus is currently under debate, but the current state of research is limited. Our aim was to investigate the association of thyroid hormone levels with prevalent and incident type 2 diabetes mellitus (T2DM) in two representative studies. METHODS AND RESULTS: Analyses are based on data from the Study of Health in Pomerania (SHIP), a German population based cohort with 4308 individuals at baseline and 3300 individuals at a five-year follow-up, and from INTER99, a Danish population-based randomized controlled trial with 6784 individuals at baseline and 4516 individuals at the five-year-follow-up...
October 25, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
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