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International Journal of Methods in Psychiatric Research

James McIntosh
Kessler k6 psychological distress scores are analyzed using a count model and item response theory (IRT) models are applied to the items which produce the k6 score and generate an alternative distress score, θ(*) . Other ways of utilizing the constituent items are also examined. The data used in the analysis comes from the 2014 National Survey of Drug Use and Health. Three important results emerge. First, θ(*) and k6 are not highly correlated and their distributions are quite different. The k6 score gives a much more favourable picture of mental health than θ(*) ...
December 28, 2016: International Journal of Methods in Psychiatric Research
Stéphane Legleye, Aida Eslami, Stéphanie Bougeard
Our aims are to describe and explain the structure of the Cannabis Abuse Screening Test (CAST) across countries. Standard statistical analyses fail to describe and explain several variables simultaneously while taking account of the group structure of individuals. The 2011 European School Survey Project on Alcohol and other Drugs (ESPAD): 5204 last-year cannabis users aged 15-16 from 13 European countries. Multigroup principal component analysis (mgPCA) and multigroup partial least squares (mgPLS). MgPCA shows that the CAST has a two-dimensional structure (frequency of use/problems and non-recreational use/dependency symptoms)...
December 15, 2016: International Journal of Methods in Psychiatric Research
Stephen J Tueller, Kiersten L Johnson, Kevin J Grimm, Sarah L Desmarais, Brian G Sellers, Richard A Van Dorn
Factor analytic work on the Positive and Negative Syndrome Scale (PANSS) and Brief Psychiatric Rating Scale (BPRS) has yielded varied and conflicting results. The current study explored potential causes of these discrepancies. Prior research has been limited by small sample sizes and an incorrect assumption that the items are normally distributed when in practice responses are highly skewed ordinal variables. Using simulation methodology, we examined the effects of sample size, (in)correctly specifying item distributions, collapsing rarely endorsed response categories, and four factor analytic models...
December 2, 2016: International Journal of Methods in Psychiatric Research
Judith M Conijn, Philip Spinhoven, Rob R Meijer, Femke Lamers
Person misfit on a self-report measure refers to a response pattern that is unlikely given a theoretical measurement model. Person misfit may reflect low quality self-report data, for example due to random responding or misunderstanding of items. However, recent research in the context of psychopathology suggests that person misfit may reflect atypical symptom profiles that have implications for diagnosis or treatment. We followed-up on Wanders et al. (Journal of Affective Disorders, 180, 36-43, 2015) who investigated person misfit on the Inventory of Depressive Symptomatology (IDS) in the Netherlands Study of Depression and Anxiety (n = 2,981)...
November 14, 2016: International Journal of Methods in Psychiatric Research
Michael H Boyle, Laura Duncan, Kathy Georgiades, Kathryn Bennett, Andrea Gonzalez, Ryan J Van Lieshout, Peter Szatmari, Harriet L MacMillan, Anna Kata, Mark A Ferro, Ellen L Lipman, Magdalena Janus
This paper discusses the need for research on the psychometric adequacy of self-completed problem checklists to classify child and adolescent psychiatric disorder based on proxy assessments by parents and self-assessments by adolescents. We put forward six theoretical arguments for expecting checklists to achieve comparable levels of reliability and validity with standardized diagnostic interviews for identifying child psychiatric disorder in epidemiological studies and clinical research. Empirically, the modest levels of test-retest reliability exhibited by standardized diagnostic interviews - 0...
November 14, 2016: International Journal of Methods in Psychiatric Research
Konstantin Mechler, Georg F Hoffmann, Ralf W Dittmann, Markus Ries
Autism spectrum disorders (ASD) have a prevalence of up to 2.7% and show significant rates of comorbidities. Pharmacological treatment can be difficult. New treatment options are needed, several are currently under investigation. Publication bias presents a major problem in current clinical research. This study was designed to quantify publication bias in rigorously designed ASD research. The database at was searched for all completed randomized controlled clinical trials investigating interventions in ASD and their results made public...
November 9, 2016: International Journal of Methods in Psychiatric Research
Rahel Bachem, Axel Perkonigg, Dan J Stein, Andreas Maercker
Adjustment disorder (AjD) is a frequent but under-researched diagnosis due in part to a lack of specific symptom criteria and adequate tools of measurement. The ICD-11 for the first time proposes a positive symptom catalogue to define AjD. This study presents a validation of the Adjustment Disorder - New Module (ADNM), the first symptom severity measure for AjD according to the ICD-11 concept. Validity and sensitivity to change were investigated in a sample of 190 individuals with a DSM-IV diagnosis of AjD...
November 9, 2016: International Journal of Methods in Psychiatric Research
Paul H Lee, Andy C Y Tse, Ka Yiu Lee
The Day Reconstruction Method (DRM) is a method to measure one's subjective affective status by soliciting information in a questionnaire about the previous day's activities. We developed a new model to examine the association of daily activities, the friendliness of interacting partners, and time-of-day on net affect scores among 10,377 adults participating in the World Health Organization's Study on global ageing and adult health (SAGE). A multilevel regression was fitted and the time-of-day effect was modeled by restricted cubic spline...
November 9, 2016: International Journal of Methods in Psychiatric Research
Matthias W Riepe, Peter Gritzmann, Andreas Brieden
According to ICD-10 and DSM-V, symptoms of depressive disorder are considered to be equally important for severity judgment. It was the goal to investigate the weight of selected symptom complexes for severity judgment. In workaday life severity judgment results from an overall impression rather than from calculating severity in different symptom complexes, separately. In fact, the drivers for overall judgment may not be known explicitly to the psychiatrist himself. A method of choice to resolve this is conjoint analysis...
November 9, 2016: International Journal of Methods in Psychiatric Research
Eline C Jochems, Hugo J Duivenvoorden, Arno van Dam, Christina M van der Feltz-Cornelis, Cornelis L Mulder
Currently, it is unclear whether Self-Determination Theory (SDT) applies to the mental health care of patients with severe mental illness (SMI). Therefore, the current study tested the process model of SDT in a sample of outpatients with SMI. Participants were 294 adult outpatients with a primary diagnosis of a psychotic disorder or a personality disorder and their clinicians (n = 57). Structural equation modelling was used to test the hypothesized relationships between autonomy support, perceived competence, types of motivation, treatment engagement, psychosocial functioning and quality of life at two time points and across the two diagnostic groups...
October 27, 2016: International Journal of Methods in Psychiatric Research
Eduardo Fonseca-Pedrero, Javier Ortuño-Sierra, Edurne Chocarro, Felix Inchausti, Martin Debbané, Julio Bobes
There have been several attempts to identify individuals potentially at high risk for psychotic-spectrum disorders using brief screening measures. However, relatively few studies have tested the psychometric properties of the psychosis screening measures in representative samples of adolescents. The main purpose of the present study was to analyse the prevalence, factorial structure, measurement invariance across gender, and reliability of the Youth Psychosis At-Risk Questionnaire - Brief (YPARQ-B) in a community-derived sample of adolescents...
October 27, 2016: International Journal of Methods in Psychiatric Research
Merav Kovatch, Daniel Feingold, Odelia Elkana, Shaul Lev-Ran
Prescription opioid medications are commonly used for the treatment of chronic pain. Assessments of problematic opioid use among pain patients are inconsistent across studies, partially due to differences between various measures. Therefore, the most appropriate measure to use is often unclear. In this study we assessed problematic opioid use in a sample of 551 individuals receiving treatment for chronic pain, using three questionnaires: the Alcohol Use Disorder and Associated Disabilities Interview Schedule - Fourth Edition (AUDADIS-IV), the Current Opioid Misuse Measure (COMM) questionnaire and Portenoy's criteria (PC)...
October 23, 2016: International Journal of Methods in Psychiatric Research
Huifang Yin, Michael R Phillips, Klaas J Wardenaar, Guangming Xu, Johan Ormel, Hongjun Tian, Robert A Schoevers
Mental health in China is of growing concern to both policy-makers and researchers. The Tianjin Mental Health Survey (TJMHS) was conducted between July 2011 and March 2012 to assess the prevalence and risk factors of mental disorders in the context of recent economic growth and other socio-demographic changes in Tianjin, a municipality of 13 million on China's eastern seaboard. A multistage cluster random sample selected using probability proportionate to size methods participated in a two-phase screening procedure: 11,748 subjects 18 or older were screened for risk of psychopathology and then an enriched risk-proportional subsample of 4,438 subjects was interviewed by psychiatrists using an expanded Chinese version of the Structured Clinical Interview for Diagnostic and Statistical Manual, Fourth Edition (DSM-IV) Axis I disorders (SCID)...
October 21, 2016: International Journal of Methods in Psychiatric Research
Claire Montlahuc, Emmanuel Curis, Sarah Flora Jonas, Frank Bellivier, Sylvie Chevret
Gaussian mixture analysis is frequently used to model the age-at-onset (AAO) in bipolar I disorder and identify homogeneous subsets of patients. This study aimed to examine whether, using admixture analysis of AAO, cross-sectional designs (which cause right truncation), unreliable diagnosis for individuals younger than 10 years old (which causes left truncation) and the selection criterion used for admixture analysis impact the number of identified subsets. A simulation study was performed. Different criteria - the likelihood ratio test (LRT), the Akaike information criterion (AIC), and the Bayesian information criterion (BIC) - were compared using no, left and/or right truncation simulated data...
October 21, 2016: International Journal of Methods in Psychiatric Research
Demet Dingoyan, Mike Mösko, Yadigar Imamoğlu, Alessa von Wolff, Jens Strehle, Hans-Ulrich Wittchen, Holger Schulz, Uwe Koch-Gromus, Andreas Heinz, Ulrike Kluge
The Composite International Diagnostic Interview (CIDI), which has been widely applied in epidemiological research, is a standardized, clinically structured interview that enables the diagnosis of mental disorders based on DSM and ICD criteria. The computerized DIA-X CIDI Version 2.8 investigated in this study is an adaptation of the German DIA-X/Munich CIDI, which was translated in a multi-step process into Turkish and used to survey the prevalence of mental disorders in individuals with Turkish migration backgrounds in Germany (N = 662)...
October 21, 2016: International Journal of Methods in Psychiatric Research
Melissa A MacLeod, Paul F Tremblay, Kathryn Graham, Sharon Bernards, Jürgen Rehm, Samantha Wells
The 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a brief measurement tool used cross-culturally to capture the multi-dimensional nature of disablement through six domains, including: understanding and interacting with the world; moving and getting around; self-care; getting on with people; life activities; and participation in society. Previous psychometric research supports that the WHODAS 2.0 functions as a general factor of disablement. In a pooled dataset from community samples of adults (N = 447) we used confirmatory factor analysis to confirm a one-factor structure...
December 2016: International Journal of Methods in Psychiatric Research
Minyoung Lee, Steven H Aggen, Takeshi Otowa, Enrique Castelao, Martin Preisig, Hans J Grabe, Catharina A Hartman, Albertine J Oldehinkel, Christel M Middeldorp, Henning Tiemeier, John M Hettema
To achieve sample sizes necessary for effectively conducting genome-wide association studies (GWASs), researchers often combine data from samples possessing multiple potential sources of heterogeneity. This is particularly relevant for psychiatric disorders, where symptom self-report, differing assessment instruments, and diagnostic comorbidity complicates the phenotypes and contribute to difficulties with detecting and replicating genetic association signals. We investigated sources of heterogeneity of anxiety disorders (ADs) across five large cohorts used in a GWAS meta-analysis project using a dimensional structural modeling approach including confirmatory factor analyses (CFAs) and measurement invariance (MI) testing...
December 2016: International Journal of Methods in Psychiatric Research
Rei Monden, Stijn de Vos, Richard Morey, Eric-Jan Wagenmakers, Peter de Jonge, Annelieke M Roest
The Food and Drug Administration (FDA) uses a p < 0.05 null-hypothesis significance testing framework to evaluate "substantial evidence" for drug efficacy. This framework only allows dichotomous conclusions and does not quantify the strength of evidence supporting efficacy. The efficacy of FDA-approved antidepressants for the treatment of anxiety disorders was re-evaluated in a Bayesian framework that quantifies the strength of the evidence. Data from 58 double-blind placebo-controlled trials were retrieved from the FDA for the second-generation antidepressants for the treatment of anxiety disorders...
December 2016: International Journal of Methods in Psychiatric Research
Amandine Luquiens, Marie-Laure Tanguy, Amine Benyamina, Marthylle Lagadec, Henri-Jean Aubin, Michel Reynaud
The aim was to develop and validate an instrument to track online problem poker gamblers with player account-based gambling data (PABGD). We emailed an invitation to all active poker gamblers on the online gambling service provider Winamax. The 14,261 participants completed the Problem Gambling Severity Index (PGSI). PGSI served as a gold standard to track problem gamblers (i.e., PGSI ≥ 5). We used a stepwise logistic regression to build a predictive model of problem gambling with PABGD, and validated it...
December 2016: International Journal of Methods in Psychiatric Research
Ahsan Rao, Amna Suliman, Giles Story, Sabine Vuik, Paul Aylin, Ara Darzi
BACKGROUND: Second-generation antipsychotics (SGAs) are often prescribed in the treatment of Behavioral and Psychological Symptoms of Dementia (BPSD), however, their use has been discouraged in light of clinical trials suggesting that they cause an increased risk of cerebrovascular accidents (CVAs). OBJECTIVE: Aim of the study was to assess relative risk of CVA in dementia patients prescribed SGA rather than first-generation antipsychotics (FGAs), through meta-analysis of population-based studies...
December 2016: International Journal of Methods in Psychiatric Research
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