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Journal of Long-term Effects of Medical Implants

Mark Phillips, Judy Baumhauer, Sheila Sprague, Jon Zoltan
The use of noninvasive bone growth stimulators is a nonoperative treatment option for fracture nonunions. The purpose of this study was to evaluate the initial effectiveness of the combined magnetic field (CMF) bone growth stimulation in the treatment of fracture nonunions. Using data from a large nonunion fracture registry, we reviewed fracture-healing-outcome data and healing times for all patients treated with a CMF bone growth stimulator during a 4-yr period. Overall, 75% of the 2370 included patients achieved fracture union...
2016: Journal of Long-term Effects of Medical Implants
Mark Phillips, Brian Drew, Sheila Sprague, Ilyas Aleem
Vertebral fractures place significant burdens on patients, caregivers, and the healthcare system at large. Nonunion is a frequent complication following vertebral fracture treatment, often resulting in significant patient pain and morbidity. Bone growth stimulators are an adjunct treatment modality proposed to increase rates of fracture healing. Combined magnetic field (CMF) bone growth stimulators have specifically been shown to increase union rates in patients with vertebral fractures. Certain populations, such as the elderly, postmenopausal women, and smokers, have demonstrated a preferentially greater response to CMF treatment...
2016: Journal of Long-term Effects of Medical Implants
Mark Phillips, Jon Zoltan, Brad A Petrisor, Sheila Sprague, Judy Baumhauer
This study evaluated the effectiveness and safety of bone growth stimulation using combined magnetic field (CMF) for the treatment of fracture nonunions. In this prospective multicenter study, patients were assessed monthly for 9 mo, or until they demonstrated a healed nonunion, and were assessed at a final follow-up 3 mo after treatment completion. The primary outcome was the presence or absence of fracture healing at the nonunion site, determined by clinical and radiographic assessment. Enrolled in this study were 112 patients with 116 fracture nonunions...
2016: Journal of Long-term Effects of Medical Implants
Chandrika Shenoy, Hani Aodah Alzahrani, Adrian R M Upton, Markad V Kamath
Epilepsy is a neurological disorder that has been diagnosed in approximately 1% of the world's population. In North America alone, more than 3 million individuals suffer from epilepsy. Antiepileptic drugs are not fully effective in some patients, and most drugs have adverse side effects. Recently, several stimulation techniques (responsive neural, vagal nerve, transcranial magnetic, and deep brain) have been used as adjunct therapies to treat medically refractive seizures. Since its Food and Drug Administration approval in 2013, responsive neural stimulation (RNS), a closed-loop electrical stimulation system, has emerged as a potential therapeutic alternative to treat patients with epilepsy (PWE)...
2016: Journal of Long-term Effects of Medical Implants
Sara Soheilifar, Mohsen Bidgoli, Erfan Abbasi Atibeh, Javad Faradmal
BACKGROUND: One of the most common complications of implant surgery is wound dehiscence followed by exposure of the implant to the oral cavity. The aim of this study was to radiographically analyze crestal bone loss around bone-level implants with wound dehiscence between the first- and second-stage surgeries. METHODS: The records of 136 implants inserted during 2013-2014 were evaluated. Patients with no history of systemic disease, drug addiction, radiotherapy, or chemotherapy were selected...
2016: Journal of Long-term Effects of Medical Implants
Ulrich M Rieger, Gabriel Djedovic, Alexander Pattiss, Gregor F Raschke, Reno Frei, Gerhard Pierer, Andrej Trampuz
Polyurethane-coated breast implants seem to be associated with lower medium- and long-term capsular contracture rates in comparison to textured or smooth implant surfaces. Although the etiology of capsular contracture is uncertain, bacterial biofilms have been suggested to trigger chronic peri-implant inflammation, eventually leading to capsular contracture. It is unknown whether polyurethane-coated implants are less prone to biofilm colonization than other implant surfaces. We extracted data from patient records included in a prospective cohort between 2008 and 2011...
2016: Journal of Long-term Effects of Medical Implants
Mariya Tohfafarosh, Alex Sevit, Jasmine Patel, Jonathan W Kiel, Arnold Greenspon, Jordan M Prutkin, Steven M Kurtz
Success of pacemakers and implantable cardioverter defibrillators may be limited by premature lead failure. Lead insulation polymers, such as polyurethane (PU) and polydimethylsiloxane (PDMS), are reported to degrade over time in vivo. PU is known to undergo oxidation, whereas PDMS undergoes surface hydrolysis. Previous studies have characterized polymer degradation in vitro, in animals or in short-term human study; however, complex effects of the biochemical and mechanical environment on the lead insulation can only be fully understood by evaluating long-term-implanted leads...
2016: Journal of Long-term Effects of Medical Implants
Amir Moeintaghavi, Hamidreza Arab, Farid Shiezadeh, Amirhossein Moradi, Mehrdad Radvar, Kazem Fatemi
The aim of the present study was to evaluate alveolar crest changes when using demineralized freeze-dried bone allograft (DFDBA) and resorbable membrane between flap and buccal bone in addition to filling the gap, as compared to merely filling the gap, when performing immediate implantation. In 18 patients with 24 single-root teeth, implants were placed immediately after extraction. In the test group (nine patients with 12 teeth), DFDBA and barrier membrane were placed between buccal crest and flap after implant placement...
2016: Journal of Long-term Effects of Medical Implants
Tsutomu Nomura, Michael P Powers, J Lawrence Katz, Sadakazu Ejiri, Tadaharu Kobayashi
This study was a histomorphometric comparison of the transmandibular implant (TMI) system and titanium implant using a confocal laser scanning microscope (CLSM). Two dogs were used. In each dog, 16 implant holes were made in the bilateral mandibular angle. Four cortical screws in the TMI, four titanium plasma spray (TPS) implants, and four hydroxyapatite (HA) coating implants were inserted and four holes were left as a control. Two dogs were sacrificed at 3 and 6 months. The samples were cut longitudinally and examined under CLSM...
2016: Journal of Long-term Effects of Medical Implants
Nathan Evaniew
Osteoporotic vertebral compression fractures affect more than 1 million patients worldwide each year. Percutaneous balloon kyphoplasty is a minimally invasive vertebral augmentation procedure that aims to stabilize fractured vertebral compression fractures rapidly and improve spinal deformity. The Fracture Reduction Evaluation (FREE) trial was the first randomized trial to compare balloon kyphoplasty against nonoperative management and it remains a landmark trial today. On the basis of this single trial, the American Academy of Orthopaedic Surgeons made a "weak" recommendation that "kyphoplasty is an option" for patients presenting with osteoporotic vertebral compression fractures...
2016: Journal of Long-term Effects of Medical Implants
Hamidreza Arab, Farid Shiezadeh, Amir Moeintaghavi, Najme Anbiaei, Satlikh Mohamadi
The aim of this clinical trial was to evaluate 6-month clinical and radiographic outcomes after surgical regenerative therapy of peri-implantitis lesions using either porous titanium granules (Natix, Tigran Technologies, Malmo, Sweden) alone or bovine bone mineral (Bio-Oss, Giestlich, Wolhusen, Switzerland) with a collagen membrane (B&B Dental Implant Company, San Pietro, Italy). Twenty-four patients having at least one implant with a peri-implantitis lesion were involved in this study. Patients were assigned randomly into two groups and treated with two different regenerative approaches...
2016: Journal of Long-term Effects of Medical Implants
Harpal S Khanuja, Samik Banerjee, Guneet S Sodhi, Michael A Mont
Intra-articular injections of corticosteroids have been used as a treatment option for degenerative arthritis of the knee for short- to mid-term symptomatic pain relief for many decades. Recently, there have been studies that have reported increased risks of periprosthetic joint infections in patients who have received these injections. In this study, we evaluated the risk of superficial, deep, and overall rate of infections in 302 patients who had received intra-articular corticosteroid infiltration within 12 months before undergoing total knee arthroplasty (TKA) and compared them with a 1:1 matched cohort who had undergone TKA, but who did not have any prior corticosteroid knee injections...
2016: Journal of Long-term Effects of Medical Implants
Mahdi Kadkhodazadeh, Zahra Alizadeh Tabari, Tahere Pourseyediyan, Kimya Najafi, Reza Amid
Periodontitis is an infectious disease of the tooth-supporting tissues. Specific periodontal pathogens trigger inflammatory responses and result in progressive bone loss, which eventually leads to exfoliation of teeth. Periimplantitis is the destructive inflammatory process affecting the soft and hard tissues surrounding dental implants. The periodontal pathogens found around failing implants are very similar to those associated with various forms of periodontal diseases. Genetic susceptibility has been known to be an important risk factor for periodontitis and periimplantitis and there have been numerous studies evaluating this in different populations...
2016: Journal of Long-term Effects of Medical Implants
Florian Kovar, Julio J Jauregui, Stacy C Specht, Erin Baker, Anil Bhave, John E Herzenberg
Nerve injury is a serious potential complication associated with clinical use of tourniquets during surgery. A novel narrow, single-use silicon ring tourniquet has been introduced, which may cause less nerve compression and provide a larger field of surgical exposure than standard wide tourniquets. We investigated both types of tourniquets in the non-dominant proximal upper arm of 15 healthy human volunteers. Pain and neurological effects were assessed during 15 minute trials with each tourniquet applied 1 week apart without anesthesia according to the manufacturers' recommendations...
2016: Journal of Long-term Effects of Medical Implants
Jeffrey E Mait, Westley T Hayes, Christopher L Blum, Robert Pivec, Christian J Zaino, Julio J Jauregui, Subrata Saha, Jaime A Uribe, William P Urban
Previous studies have examined multiple suture techniques for the repair of ruptured tendons. In this study, we investigated how the two- and four-stranded Krackow suture weave techniques compared with a novel Krackow/Bunnell suture technique. Our hypothesis was that the Krackow/Bunnell suture would have greater strength compared with the two- and four-stranded Krackow suture in terms of resistance to pullout from the muscle tendon. Thirty fresh bovine Achilles tendons were assigned randomly to three groups: (1) two-stranded Krackow, (2) fourstranded Krackow, and (3) the Krackow/Bunnell combination...
2016: Journal of Long-term Effects of Medical Implants
Justin Tsai, Robert Pivec, Julio J Jauregui, Westley T Hayes, Marlon McLeold, Qais Naziri, Bhaveen H Kapadia, Subrata Saha, Jaime A Uribe
Injuries involving the distal tibiofibular syndesmosis can lead to critical destabilization of the ankle mortise. Although specific indications for operative fixation remain unclear, accurate reduction of the syndesmosis has been correlated with the best functional outcomes. The purpose of this study was to evaluate the maximum torque and rotation to failure after fixation with a novel construct. Seven pairs (14 ankles) of embalmed cadaveric lower legs, disarticulated at the knee, were obtained. Each pair was randomly assigned to receive either two TightRopes (Arthrex) or a plate-and-screw construct with one TightRope...
2016: Journal of Long-term Effects of Medical Implants
Anil Bhave, James Corcoran, Jeffery J Cherian, Michael A Mont
Knee stiffness is a common complication after total knee arthroplasty (TKA). Despite studies published on the surgical management of reduced range of motion (ROM) after TKA, there is limited evidence on the nonoperative management of joint and soft tissue imbalances possibly contributing to reduced knee ROM. This report assesses changes in ROM, pain, function, and patellar tendon length after Astym® joint mobilization use. A 38-year-old male professional skier had a right TKA 3 months before presentation with 2 subsequent manipulations under anesthesia secondary to persistent knee stiffness...
2016: Journal of Long-term Effects of Medical Implants
Michael A Clark, Steven J Cowart, Jonathan Pellet, David M Cearley, Styles L Bertrand
Surgical treatment for adolescent idiopathic scoliosis (AIS) has evolved over the past decades to the point where instrumented arthrodesis with all pedicle screw and rod constructs is commonplace. Although these constructs provide superb correction and fixation, their financial burden is substantial. Here, we present a more cost-effective technique using a combination of pedicle screws (serving as the construct base), a sagittal precontoured unit rod, and sublaminar wires to provide segmental correction for the surgical treatment of AIS...
2016: Journal of Long-term Effects of Medical Implants
Surena Vahabi, Maryam Torshabi, Mohammad Mohammadi
Guided bone regeneration using demineralized freeze-dried bone allograft (DFDBA) and growth factors (GFs) is a current goal in implant dentistry because of their potential osteoinductive abilities. Regarding controversial results, the purpose of this study was to compare the osteoinductivity of three different DFDBAs from two different banks with two different GFs: transforming growth factor-beta (TGF-β) and platelet-derived growth factor (PDGF). MG-63 osteoblast-like cells were exposed to two different concentration of commercial DFDBAs (10 and 20 mg/mL) and growth factors (5 and 10 ng/mL)...
2016: Journal of Long-term Effects of Medical Implants
Robert Krushell, Manoshi Bhowmik-Stoker, Carinna Kison, Mary O'Connor, Jeffery J Cherian, Michael A Mont
We conducted a prospective multicenter study in which outcome-related expectations of 236 primary total hip arthroplasty patients were determined. Clinical surveys and radiographs were used to determine the relationship between postoperative level of patient satisfaction and patient-reported and radiographic outcomes. At 1 year, 82.6% of expectations were achieved, most of the time with high satisfaction (89.3%). Younger, lower body-mass index, male patients were more likely to expect the surgery to benefit "return to work" and "sexual function", whereas older, heavier patients, selected "elimination of assistive devices" and "independence in daily activities"...
2016: Journal of Long-term Effects of Medical Implants
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