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Journal of Long-term Effects of Medical Implants

Ahilan Anantha Krishnan, Rupesh Ghyar, Bhallamudi Ravi
Fatigue performance of tibial tray in total knee arthroplasty (TKA) is of critical importance in terms of longevity of the prosthesis. Standards have been proposed by American Society for Testing and Materials (ASTM) and International Organization for Standardization (ISO) to ensure its long-term structural integrity. The aim of the current study is to evaluate the effect of modularity in the tibial tray following the testing standards, using finite element analysis. Goodman and Sines criteria were used to compare the fatigue safety factor (FSF) of four modular designs versus the two conventional designs...
2016: Journal of Long-term Effects of Medical Implants
Andreas F Mavrogenis, John Galanopoulos, Christos Vottis, Panayiotis D Megaloikonomos, Emanuela Palmerini, Zinon T Kokkalis
Angiosarcoma of bone is a rare high-grade malignant vascular tumor accounting for <1% of malignant bone tumors. Tumor location in the distal radius is very rare. Complete surgical resection with limb salvage surgery or amputation is essential for the outcome of the patient. However, the literature is vague regarding the best surgical approach for resection of the distal radius and the optimal reconstruction option after a bone tumor resection. Several reconstruction techniques have been described, varying from arthrodesis to arthroplasties...
2016: Journal of Long-term Effects of Medical Implants
Yijun Fu, Bin Li, Jean-Michel Bourget, Olexandr Bondarenko, Jing Lin, Randolph Guzman, Royston Paynter, Denis Desaulniers, Boyin Qin, Lu Wang, Lucie Germain, Ze Zhang, Robert Guidoin
The Bentall procedure introduced in 1968 represents an undisputed cure to treat multiple pathologies involving the aortic valve and the ascending thoracic aorta. Over the years, multiple modifications have been introduced as well as a standardized approach to the operation with the goal to prevent long-term adverse events. The BioValsalva prosthesis provides a novel manner to more efficiently reconstruct the aortic valve together with the anatomy of the aortic root with the implantation of a valved conduit...
2016: Journal of Long-term Effects of Medical Implants
Nan-Xiang Xiong, Daisong Albert Tan, Peng Fu, Yi-Zhi Huang, Song Tong, Hua Yu
We report on a female patient who received microvascular decompression due to hemifacial spasm. Neuro-Patch® was used during the operation to repair and replace damaged dura mater. Six days after the operation, the incision wound was found to be infected. Abscesses were present deep in the incision. However, because the artificial dura mater was attached so tightly to the original dura mater, the infection was not able to spread inside the skull. After 3 months of meticulous wound cleaning and drug treatment to promote the growth of granulation tissue, we were able to gradually achieve healing of the infection without having to remove the non-absorbable artificial dura mater...
2016: Journal of Long-term Effects of Medical Implants
Robert Guidoin, Yijun Fu, Bin Li, Nihal Weerasena, Jean-Michel Bourget, Royston Paynter, Xinxin Li, Jing Lin, Lu Wang, Boyin Qin, Randolph Guzman, Denis Desaulniers, Guy Dionne, Lucie Germain, Ze Zhang
The reconstruction of the right ventricular outflow tract (RVOT) system represents a considerable challenge for both manufacturers and surgeons because the patients requiring this type of devices have a very diverse set of anatomical challenges that can lead to complications and subsequent early device failures. We conducted an indepth investigation of a porcine-valve conduit explanted from a patient following an adverse event. A control device was analyzed as a reference. The rapid aging of the porcine valve in the right side of the heart together with major thrombus formation raises several questions...
2016: Journal of Long-term Effects of Medical Implants
Ilias Katsougrakis, Alexandros P Apostolopoulos, Samantha Z Tross
UNLABELLED: Femoral-neck stress fractures are relatively rare and may present as sports-related injuries. The presentation is variable, and prompt diagnosis facilitates the earliest return to pre-morbid functional activity levels. Delayed detection may precipitate femoral non-union or avascular necrosis, resulting in long-term functional deficit. AIMS: We describe the clinical, diagnostic and therapeutic approach of a femoral-neck stress fracture that occurred in a 28-year-old female recreational runner...
2016: Journal of Long-term Effects of Medical Implants
George S Sapkas, Andreas F Mavrogenis, Elias Papastathis, Kostas Tsiavos, Vasilios Igoumenou, Panayiotis D Megaloikonomos, Ioannis Galanopoulos, Konstantinos Soultanis, Elias C Papadopoulos, Panayiotis J Papagelopoulos
Parkinson's disease is a degenerative disorder of the central nervous system affecting the substantia nigra in the midbrain. It accounts for 1.5% of the population in Europe over 60 years of age. Recent advances in the medical treatment of Parkinson's disease have improved the quality of life and life expectancy of the patients. However, it remains a debilitating disease. Spinal disorders are frequent in these patients, and as the population ages, more patients with Parkinson's disease are expected to require spinal surgery...
2016: Journal of Long-term Effects of Medical Implants
Todd P Pierce, Jeffery J Cherian, Michael A Mont
Pain and dysfunction leading to decreased range-of-motion following total knee arthroplasty (TKA) is a common complication that may require treatment beyond standard rehabilitation efforts. In this review, we discuss the use of static and dynamic stretch devices to treat these range-of-motion dysfunctions. There are two mechanisms by which these devices work: dynamic stretch applies a constant low force, which allows for a variable soft-tissue displacement as they stretch, and static progressive stretch increases displacement, which allows for a constant displacement at a variable force leading to tissue stress relaxation...
2015: Journal of Long-term Effects of Medical Implants
Paul W Perdue, Yoseph A Rosenbaum, Dean C Perfetti, Bhaveen H Kapadia, Matthew R Boylan, Julio J Jauregui, Carl B Paulino
Indications for open reduction and internal fixation (ORIF) of tibia and/or fibula fractures vary; however, some patients require removal of hardware (ROH) due to various complications. Currently, data evaluating the epidemiology of and risk factors for ROH of the tibia/fibula are limited. We examined the associations between tibia/fibula fractures and (1) characteristics of fractures requiring ORIF, (2) indications for ROH, (3) demographic risk factors for ROH; (4) length of stay, and (5) total hospital charges...
2015: Journal of Long-term Effects of Medical Implants
Clayton C Bettin, William B Sisson, Anita L Kerkhof, William M Mihalko
Gelsolin (GSN) has been implicated in inflammatory reactions in asthmatic patients and may be a marker for acute or chronic reactions in synovial tissue. Detection of increased levels of GSN in synovial fluid could differentiate between aseptic loosening (low GSN) and hypersensitivity reaction (high GSN). Synovial fluid from both knees of 7 cadaver specimens with unilateral TKA was analyzed using ELISA for GSN levels. Components were explanted after spiral CT scans to determine wear patterns and loosening. Results were compared to synovial fluid from 7 consecutive TKA revisions for aseptic failure...
2015: Journal of Long-term Effects of Medical Implants
Michael J Faloon, Mark Ruoff, Chetan Deshpande, Donald Hohman, Conor Dunn, Nicholas Beckloff, Dipak V Patel
Vertebral compression fractures are a significant source of morbidity and mortality among patients of all age groups. These fractures result in both acute and chronic pain. Patients who sustain such fractures are known to suffer from more comorbidities and have a higher mortality rate compared with healthy people in the same age group. In recent years, balloon kyphoplasty has become a popular method for treating vertebral compression fractures. However, as longer-term follow-up becomes available, the effects of cement augmentation on adjacent spinal segments require investigation...
2015: Journal of Long-term Effects of Medical Implants
Julio J Jauregui, Jeffery J Cherian, Todd P Pierce, Randa K Elmallah, Michael A Mont
Unplanned hospital readmissions within 30 days of surgery result in reimbursement penalties following total knee arthroplasty (TKA). Therefore, evaluating current readmission rates and comparing these to national levels is one way to self-assess and determine possible areas where improvements can be made. In this study, the 30-day readmission data for 845 TKAs performed with a single prosthesis were compared to the readmission data from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) Database of 12,035 TKAs...
2015: Journal of Long-term Effects of Medical Implants
Jeffery J Cherian, Mark J McElroy, Bhaveen H Kapadia, Anil Bhave, Michael A Mont
Osteoarthritis of the knee can lead to substantial disability. The purpose of this study was to evaluate the outcomes of a neuromuscular electrical stimulation (NMES) device in a small case series of treatment of quadriceps muscle weakness and decreased function in patients with knee osteoarthritis. We evaluated isokinetic quadriceps muscle strength, objective functional improvement, subjective functional improvement, quality of life, and pain relief. Patients were then matched with a previously studied cohort with similar osteoarthritic characteristics...
2015: Journal of Long-term Effects of Medical Implants
Andreas F Mavrogenis, Panayiotis D Megaloikonomos, George N Panagopoulos, Panayiotis J Papagelopoulos, Theofilos Theophanides, Jane Anastassopoulou
Although radiation therapy is an essential treatment of cancers, it is associated with unwanted complications. The purpose of this review is to summarize the current knowledge regarding the side effects of radiation in bone and articular cartilage and to recommend Fourier transform infrared spectroscopy to monitor the differences in infrared spectra between healthy and irradiated bone and cartilage.
2015: Journal of Long-term Effects of Medical Implants
Stephanie Hinton, Mohammed M Beyari, Kim Madden, Hanadi A Lamfon
The use of a randomized controlled trial (RCT) research design is considered the gold standard for conducting evidence-based clinical research. In this present study, we aimed to assess the quality of RCTs in dentistry and create a general foundation for evidence-based dentistry on which to perform subsequent RCTs. We conducted a systematic assessment of bias of RCTs in seven general dentistry journals published between January 2011 and March 2012. We extracted study characteristics in duplicate and assessed each trial's quality using the Cochrane Risk of Bias tool...
2015: Journal of Long-term Effects of Medical Implants
Robert Pivec, Kimona Issa, Bhaveen H Kapadia, Jeffery J Cherian, Aditya V Maheshwari, Peter M Bonutti, Michael A Mont
As the number of total hip arthroplasties (THA) increases, the number of fractures will increase as well. The purpose of this study was to determine the incidence and prevalence of intra- and post-operative periprosthetic fractures following THA based on national joint registry data and to create a projection model that estimates the future fracture burden. Registry data from multiple joint registries were analyzed. Data on the incidence and prevalence of intra- and post-operative periprosthetic fractures were extracted...
2015: Journal of Long-term Effects of Medical Implants
Megan M Sorich, Jeffery J Cherian, Mark J McElroy, Samik Banerjee, Lynne C Jones, Caterina P Minniti, Michael A Mont
Osteonecrosis of the hip can lead to advanced arthritis in typically young patients. Hematologic disorders comprise one group of potential causes. These include sickle cell anemia, hemophilia, aplastic anemia, thalassemia, and acute lymphoblastic leukemia. Depending on the stage of disease, treatment options include non-operative management, joint-preserving procedures (percutaneous drilling, core decompression, and vascularized or non-vascularized bone grafting), and joint arthroplasty (resurfacing arthroplasty and THA)...
2015: Journal of Long-term Effects of Medical Implants
Sanjoy Roy, Rashad Carlton, Martin Weisberg, Ryan Clark, Kristen Migliaccio-Walle, Hector Chapa
We used an economic model to assess the impact of using the GYNECARE INTERCEED absorbable adhesion barrier for reducing the incidence of postoperative adhesions in open surgical gynecologic procedures. Caesarean section surgery, hysterectomy, myomectomy, ovarian surgery, tubal surgery, and endometriosis surgery were modeled with and without the use of GYNECARE INTERCEED absorbable adhesion barrier. Incremental GYNECARE INTERCEED absorbable adhesion barrier material costs, medical costs arising from complications, and adhesion-related readmissions were considered...
2015: Journal of Long-term Effects of Medical Implants
Chuan Silvia Li, Christopher Vannabouathong, Sheila Sprague, Mohit Bhandari
Osteoarthritis (OA) is a chronic, degenerative disease that is highly prevalent in the population, yet the factors that affect purchasing decisions related to this condition are poorly understood. A questionnaire was developed and administered to hospital executives across North America to determine the factors that affect purchasing decisions related to OA. Thirty-four individuals participated in the survey. Clinical evidence and cost effectiveness were deemed to be the most important factors in the process of making purchasing decisions...
2015: Journal of Long-term Effects of Medical Implants
Dan Strain, Chuan Silvia Li, Mark Phillips, Olga Monteagudo Piqueras, Mohit Bhandari
We investigated the efficacy and cost effectiveness of the KineSpring System in the Spanish healthcare system, as compared to other standard treatments methods. Cost-utility ratios were calculated using derived cost data and we calculated quality-adjusted life years (QALYs) gained for each method of treatment. Cost-utility ratios were calculated assuming lifetime and 10-year durability. Assuming lifetime durability, cost-utility ratios of total knee arthroplasty (TKA), unicompartmental knee arthroplasty (UKA), high tibial osteotomy (HTO), KineSpring System, and conservative treatments, compared to no treatment, are €2348 ± 70/QALYs, €2040 ± 61/QALYs, €2281 ± 68/ QALY, €1669 ± 268/QALYs, and €11,688 ± 2185/QALYs, respectively...
2015: Journal of Long-term Effects of Medical Implants
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