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European Journal of Ophthalmology

Francesco Parmeggiani, Vanessa Barbaro, Angelo Migliorati, Paolo Raffa, Patrizia Nespeca, Katia De Nadai, Claudia Del Vecchio, Giorgio Palù, Cristina Parolin, Enzo Di Iorio
PURPOSE: To identify novel mutations in the retinitis pigmentosa GTPase regulator (RPGR) gene and retinitis pigmentosa 2 (RP2) gene underlying X-linked retinitis pigmentosa (XLRP) and assess genotype-phenotype correlations. METHODS: The patient cohort, consisting of 13 individuals from 3 unrelated XLRP families, underwent comprehensive ophthalmologic examination. The open reading frames of RPGR and RP2 were analyzed with Sanger sequencing in each patient. The identified genetic variants were defined as mutations or polymorphisms on the basis of their pathological effect...
October 21, 2016: European Journal of Ophthalmology
Vujica Markovic, Dragan Vukovic, Aleksandra Radosavljevic, Ivan Marjanovic
PURPOSE: To investigate the possible association between acquired ectropion uveae and blunt trauma to the eye. We present 3 cases of acquired ectropion uveae that occurred after blunt trauma to the eye. There are no previously published data on possible association of these conditions. METHODS: A retrospective review was conducted of patients with ectropion uveae and eye injury at University Eye Hospital over a 10-year period (2006-2016). We analyzed medical records and clinical findings...
October 21, 2016: European Journal of Ophthalmology
Dan Călugăru, Mihai Călugăru
No abstract text is available yet for this article.
October 18, 2016: European Journal of Ophthalmology
Anton M Kolomeyer, Ken K Nischal, Ellen Mitchell
PURPOSE: To report a case of bilateral cavernous sinus thrombosis (CST) in a patient with tacrolimus-associated posttransplant thrombotic microangiopathy. METHODS: Case report. RESULTS: An 8-year-old boy with a medical history of orthotopic heart transplant, posttransplant lymphoproliferative disease, and recurrent infections was hospitalized for nausea, vomiting, and diarrhea. His ocular history included accommodative esotropia, hyperopia with astigmatism, Molluscum contagiosum lid lesions, and idiopathic intracranial hypertension...
October 13, 2016: European Journal of Ophthalmology
Katja Hatz, Ulrike Schneider, Bernhard Henrich, Beatrice Braun, Stefan Sacu, Christian Prünte
PURPOSE: To evaluate retreatment indications/morphologic responses to ranibizumab monotherapy and combination with verteporfin photodynamic therapy (PDT). METHODS: A total of 40 patients received 3 monthly intravitreal ranibizumab 0.3 mg injections combined with either PDT or sham PDT at baseline (1:1) followed by as-needed ranibizumab based on predetermined vision/anatomical criteria. RESULTS: Retreatment criteria were visual acuity (VA) loss (59%/58%), central retinal thickness (CRT) increase (27%/26%), or both (14%/16%)...
October 13, 2016: European Journal of Ophthalmology
Sarah Moussa, Alois Dexl, Eva Maria Krall, Marie Dietrich, Eva-Maria Arlt, Günther Grabner, Josef Ruckhofer
PURPOSE: To evaluate and compare visual and refractive outcomes after laser-assisted in situ keratomileusis (LASIK) surgery for the correction of myopia or myopic astigmatism using 3 different treatment protocols. METHODS: We included 736 eyes of 369 patients (age 18-62 years) divided into 3 groups: 235 eyes of 118 patients (MEL80 group) undergoing LASIK using optimized aspheric ablation profiles (MEL80 excimer laser; Carl Zeiss Meditec), 248 eyes of 124 patients (Wavescan group) undergoing wavefront-guided (WFG) LASIK (STAR S4IR excimer laser + Wavescan aberrometer; Abbott Medical Optics), and 253 eyes of 127 patients (iDesign group) undergoing WFG LASIK (STAR S4IR excimer laser + iDesign system; Abbott Medical Optics)...
October 10, 2016: European Journal of Ophthalmology
Michael Mimouni, Achia Nemet, Russell Pokroy, Tzahi Sela, Gur Munzer, Igor Kaiserman
PURPOSE: To evaluate the effect of astigmatism axis on uncorrected distance visual acuity (UDVA) in emmetropic eyes that underwent laser refractive surgery. METHODS: This retrospective study included patients who underwent laser in situ keratomileusis or photorefractive keratectomy between January 2000 and December 2015 at the Care-Vision Laser Centers, Tel Aviv, Israel. Eyes with a 3-month postoperative spherical equivalent between -0.5 D and 0.5 D were included in this study...
October 8, 2016: European Journal of Ophthalmology
Lauren Van Lancker, Robert Petrarca, Kyros Moutsouris, Panos Masaoutis, George Kampougeris
PURPOSE: To report the response of participants switching from ranibizumab to aflibercept treatment for neovascular age-related macular degeneration (nAMD) requiring further anti-vascular endothelial growth factor treatment. METHODS: In this retrospective case review of 68 participants treated in a single hospital, all participants, prior to switching, received ranibizumab injections only. Best-corrected visual acuity (BCVA), clinical examination, and optical coherence tomography (OCT) were performed at each visit...
October 3, 2016: European Journal of Ophthalmology
Marina Trento, Lorena Charrier, Martina Salassa, Stefano Merlo, Pietro Passera, Anatolie Baltatescu, Franco Cavallo, Massimo Porta
PURPOSE: Microvascular and macrovascular complications of diabetes, such as retinopathy and nephropathy, progress over time and may be associated with cognitive decline. In this article, we aim to gain further insight into the association between cognitive function and retinopathy in type 2 diabetes. METHODS AND RESULTS: In this observational 8-year prospective study of 498 outpatients, demographic and clinical variables were monitored, along with retinopathy, depression, anxiety, and cognitive function...
October 3, 2016: European Journal of Ophthalmology
Pablo Hernández-Martínez, Rosa Dolz-Marco, David Hervás-Marín, Maria Andreu-Fenoll, Roberto Gallego-Pinazo, José Fernando Arévalo
PURPOSE: To evaluate the association between subfoveal choroidal thickness and the visual outcome in eyes with type 1 choroidal neovascularization (CNV) due to neovascular age-related macular degeneration (nAMD). METHODS: This was a retrospective, longitudinal, cross-sectional study including patients diagnosed with nAMD type 1 lesions managed with intravitreal injections of ranibizumab in a PRN strategy during 24 months. Retrospective chart review of patients with type 1 CNV recording the visual acuity, number of intravitreal injections, multimodal imaging data, and follow-up period was performed...
September 17, 2016: European Journal of Ophthalmology
Prethy Rao, Yoshihiro Yonekawa, Benjamin J Thomas, Kimberly A Drenser
PURPOSE: To compare the sensitivities of spectral-domain optical coherence tomography (SD-OCT) versus time-domain OCT (TD-OCT) in identifying epiretinal membranes (ERM) preoperatively in patients who underwent surgery for full-thickness macular holes (FTMH). METHODS: This is an interventional retrospective case series of 59 eyes diagnosed with FTMHs who underwent 25-G pars plana vitrectomy with internal limiting membrane peeling between 2009 and 2015. Preoperative OCTs were obtained by SD-OCT (Spectralis, Heidelberg, Germany) or TD-OCT (Stratus, Carl Zeiss Meditec, Dublin, CA, USA)...
September 17, 2016: European Journal of Ophthalmology
Kentaro Nishida, Hirokazu Sakaguchi, Motohiro Kamei, Nobuhiko Shiraki, Yoshihito Oura, Taku Wakabayashi, Chikako Hara, Yoko Fukushima, Tatsuhiko Sato, Kaori Sayanagi, Shigeru Sato, Masakatsu Fukuda, Kohji Nishida
PURPOSE: To establish geometrically based methods for simulating panretinal laser photocoagulation (PRP) for the photocoagulation index. METHODS: A formula for calculating the curved surface area of a spherical dome was used for the simulation. If the radius of the dome is c and the height of the dome is h, then the curved surface area (S) of the dome is S = π (c2 + h2). We calculated the area of the whole retina using this formula and the anatomical dimensions of the standard eyeball...
September 13, 2016: European Journal of Ophthalmology
Frederic Matonti, Vincent Soler
No abstract text is available yet for this article.
September 13, 2016: European Journal of Ophthalmology
Elad Moisseiev, Sam Abbassi, Susanna S Park
PURPOSE: To compare the clinical outcome of eyes with acute bacterial endophthalmitis treated with intravitreal injection of antibiotics with or without intravitreal dexamethasone. METHODS: This was a retrospective chart review of 63 eyes diagnosed with acute bacterial endophthalmitis and treated with vitreous tap and intravitreal injection of antibiotics, 19 eyes (30.2%) with and 44 eyes (69.8%) without concurrent intravitreal dexamethasone. RESULTS: Visual acuity had significantly improved by 1 week and was maintained long-term (p<0...
September 13, 2016: European Journal of Ophthalmology
David Cordeiro Sousa, Inês Leal, Carlos Marques-Neves, Filomena Pinto, Luís Abegão Pinto
PURPOSE: To investigate the association between anterior lamina cribrosa depth (ALCD), determined with enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT), and intraocular pressure (IOP) in a healthy Portuguese population. METHODS: In this cross-sectional observational study conducted between January and July 2015, 2 optic nerve head (ONH)-centered EDI-OCT cross-scans were performed and ALCD was defined as the perpendicular distance between the line connecting both edges of Bruch's membrane opening and the anterior border of the lamina cribrosa at the maximum depth point...
September 13, 2016: European Journal of Ophthalmology
Jacob B Gross, Garvin H Davis, Nicholas P Bell, Robert M Feldman, Lauren S Blieden
PURPOSE: To describe a new surgical technique to effectively close large (>180 degrees) cyclodialysis clefts. METHODS: Our method involves the use of procedures commonly associated with repair of retinal detachment and complex cataract extraction: phacoemulsification with placement of a capsular tension ring followed by pars plana vitrectomy and gas tamponade with light cryotherapy. We also used anterior segment optical coherence tomography (OCT) as a noninvasive mechanism to determine the extent of the clefts and compared those results with ultrasound biomicroscopy (UBM) and gonioscopy...
September 13, 2016: European Journal of Ophthalmology
Dan Călugăru, Mihai Călugăru
No abstract text is available yet for this article.
September 13, 2016: European Journal of Ophthalmology
Rodolfo Mastropasqua, Lisa Toto, Peter Angelo Mattei, Marta Di Nicola, Isaia Antonio Luca Zecca, Paolo Carpineto, Luca Di Antonio
PURPOSE: To assess the reproducibility and repeatability of foveal avascular zone (FAZ) area measurements using swept-source optical coherence tomography angiography (SS-OCTA) in healthy subjects. METHODS: Sixty-four eyes of 64 healthy volunteers were randomly subjected to FAZ area measurements using SS-OCTA by 2 examiners in 2 different sessions. RESULTS: The FAZ areas measured by the first and second observer were 0.269 ± 0.092 mm2 and 0...
September 9, 2016: European Journal of Ophthalmology
Rozina Noristani, Tim Schultz, H Burkhard Dick
PURPOSE: To report a patient who developed a white cataract after Nd:YAG laser vitreolysis with a posterior capsule defect. METHODS: Femtosecond laser-assisted capsulotomy was performed for optic capture fixation in a patient with a cataract due to a posterior capsule defect after Nd:YAG laser-vitreolysis. RESULTS: A 55-year-old, highly myopic woman presented with visual impairment 4 days after Nd:YAG laser vitreolysis due to preexisting floaters...
September 9, 2016: European Journal of Ophthalmology
James E Neffendorf, Bhaskar Gupta, Tom H Williamson
PURPOSE: To compare the intraoperative complications between 23-G and 20-G instrumentation in patients undergoing pars plana vitrectomy (PPV). METHODS: This was a retrospective comparative study of 4,274 PPV procedures by the same surgical team between 1998 and 2016. A total of 2,648 operations were carried out with 20-G surgery and 1,626 operations with 23-G surgery. Main outcome measures were the incidence of choroidal haemorrhage, iatrogenic retinal break, and lens touch...
September 9, 2016: European Journal of Ophthalmology
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