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European Journal of Ophthalmology

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https://www.readbyqxmd.com/read/30428702/efficacy-of-ultra-low-dose-0-1-mg-ranibizumab-intravitreal-injection-for-treatment-of-prethreshold-type-1-retinopathy-of-prematurity-a-case-series
#1
Islam Sh Ahmed, Ahmed Ma Hadi, Hassan H Hassan
AIM: To report the results of treatment of type 1 prethreshold retinopathy of prematurity using intravitreal injection of ultra-low dose of ranibizumab (0.1 mg in 0.01 mL). DESIGN: A retrospective observational case series study. METHODS: Review of files of eligible infants who received this form of treatment to determine the outcome of treatment and any associated ocular or systemic side effects. RESULTS: The study included 24 eyes of 12 preterm infants with mean gestational age of 29...
November 15, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30426773/recurrent-pax-6-mutation-in-a-chinese-family-with-congenital-aniridia-progressive-cataracts-and-mental-retardation
#2
Dou-Dou Chen, Tao Yang, Si-Quan Zhu
BACKGROUND: One prominent pathological feature of congenital aniridia is hypoplasia of the iris, often accompanied by other eye abnormalities. The objective of this study is to identify gene mutations responsible for autosomal dominance in a Chinese family with congenital aniridia, progressive cataracts and mental retardation. METHODS: A total of 11 family members, including 6 affected and 5 unaffected individuals were recruited. Whole exome sequencing was performed on the proband and Sanger sequencing was applied to identify the causal mutation in the other family members and control samples...
November 14, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30426767/surgical-timing-and-presence-of-a-vitreoretinal-fellow-on-postoperative-adverse-events-following-pars-plana-vitrectomy
#3
Ryan A Shields, Cassie A Ludwig, Matthew A Powers, Jonathan D Tijerina, Ira H Schachar, Darius M Moshfeghi
INTRODUCTION: To evaluate the adverse event rate following pars plana vitrectomy as a function of surgical start time and the presence of a vitreoretinal fellow. METHODS: Single-institution retrospective cohort study of patients undergoing pars plana vitrectomy from 1 January 2016 to 31 December 2016 at Stanford University School of Medicine (Palo Alto, CA, USA). Records were reviewed for surgical start time, the presence of vitreoretinal fellow, and postoperative adverse events defined as any finding deviating from the expected postoperative course requiring observation or intervention...
November 14, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30421623/phakic-intraocular-lens-as-a-temporary-barrier-in-aphakic-descemet-s-membrane-endothelial-keratoplasty
#4
Yusrah Shweikh, Alfonso Vasquez-Perez, Bruce D Allan
BACKGROUND: Descemet's membrane endothelial keratoplasty has a lower risk of endothelial rejection than Descemet's stripping automated endothelial keratoplasty. In aphakic eyes requiring endothelial transplantation, approaches aimed at reducing the risk of posterior graft dislocation in Descemet's stripping automated endothelial keratoplasty are not transferable to Descemet's membrane endothelial keratoplasty. TECHNIQUE: Here we describe the use of an implantable collamer lens placed over the iris to provide a temporary intraoperative platform, to facilitate graft unfolding and to avoid posterior graft dislocation in an aphakic, vitrectomised eye with a fixed, dilated pupil in a young patient with chronic uveitis and previous failed Descemet's stripping automated endothelial keratoplasty...
November 13, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30421618/evaluation-of-pro-re-nata-prn-and-treat-and-extend-bevacizumab-treatment-protocols-in-sorsby-fundus-dystrophy
#5
Georgios Tsokolas, Hussein Almuhtaseb, Andrew Lotery
PURPOSE: To describe long-term outcomes with intravitreal Bevacizumab for choroidal neovascularization secondary to Sorsby fundus dystrophy. MATERIALS/METHODS: Observational case series. RESULTS: Two sisters of the same family formally diagnosed with Sorsby fundus dystrophy were followed-up for 12 years. The elder sister (S1) presented with significant decline in vision due to choroidal neovascularization in her right eye (OD). She developed choroidal neovascularization 3 years later in her left eye (OS)...
November 13, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30409043/multimodal-imaging-in-a-young-male-with-osteogenesis-imperfecta-complicated-with-choroidal-neovascularization
#6
Riccardo Francesco Bellanca, Fabio Scarinci, Mariacristina Parravano
PURPOSE: To evaluate the role of multimodal imaging in the diagnosis and monitoring of patients with osteogenesis imperfecta complicated with choroidal neovascularization. CASE REPORT: A 28-year-old man, diagnosed with osteogenesis imperfecta, was referred 2 months after the appearance of central scotoma and metamorphopsia in the right eye. The patient underwent a complete ophthalmological evaluation including visual acuity examination as well as ophthalmoscopy, spectral-domain optical coherence tomography, optical coherence tomography angiography, fundus autofluorescence imaging, fluorescein angiography and microperimetry...
November 8, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30409042/effect-of-microalbuminuria-on-macular-thickness-in-patients-with-type-2-diabetes-mellitus
#7
Cemile Ucgul Atilgan, Kadir Gokhan Atilgan, Pinar Kosekahya, Mehtap Caglayan, Selam Yekta Sendul, Pelin Yilmazbas
PURPOSE: To investigate the effect of microalbuminuria on macular thickness in patients with type-2 diabetes mellitus with no or mild diabetic retinopathy and to investigate the relationship between macular thickness and metabolic parameters. MATERIALS AND METHODS: Fifty eight eyes of 58 patients without diabetic retinopathy (group 1) in microalbuminuria stage, 42 eyes of 42 patients with mild diabetic retinopathy (group 2) in microalbuminuria stage, and 50 eyes of 50 patients without diabetic retinopathy and microalbuminuria (group 3) were included in this study...
November 8, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30394803/a-rare-case-of-evans-syndrome-associated-with-sudden-loss-of-vision-a-case-report
#8
Laila T Ababneh, Ikhlas H Mahmoud, Hala S Al-Rimawi
PURPOSE: To report a case of Evans syndrome with a vascular occlusive event leading to severe loss of vision. CASE REPORT: A 12-year-old boy with Evans syndrome presented with painless acute loss of vision in the left eye during a period of remission from the disease. Examination showed visual acuity of hand motion in the left eye, left relative afferent pupillary defect, pale optic nerve head, and attenuated vessels. Optical coherence tomography showed thin macula in both eyes, and fundus fluorescein angiography revealed delayed filling time of the arterial phase in the left eye, with attenuation and sclerosis of the arterioles...
November 5, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30384777/characterization-of-the-effect-of-intracorneal-ring-segment-in-corneal-ectasia-after-laser-refractive-surgery
#9
Cristina Peris-Martínez, Inmaculada Bueno-Gimeno, Izaskun Alvarez-Arana, David P Piñero, Andrés Gené-Sampedro
PURPOSE: To evaluate the visual, refractive, topographic, pachymetric, and biomechanical outcomes after intracorneal ring segment implantation in corneas with post-LASIK ectasia. METHODS: Retrospective longitudinal study enrolling 26 eyes of 22 patients with post-LASIK ectasia and undergoing intracorneal ring segment implantation (KeraRing®, Mediphacos) using a 60-kHz femtosecond laser (IntraLase®, IntraLase Corp.) for corneal tunnelization. Visual, refractive, anterior, and posterior corneal topographic (Pentacam HR, Oculus), pachymetric, and corneal biomechanical changes (Ocular response Analyzer, Reichert) were evaluated during a 12-month follow-up...
November 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30378440/evaluation-of-corneal-epithelial-wound-healing-after-penetrating-keratoplasty-in-patients-receiving-a-new-matrix-therapy-agent-regenerating-agent
#10
Rémy Jullienne, Thibaud Garcin, Emmanuel Crouzet, Zhiguo He, Didier Renault, Gilles Thuret, Philippe Gain
OBJECTIVES: Complete epithelial wound healing is a milestone in early postoperative care after penetrating keratoplasty. The re-epithelialization rate after penetrating keratoplasty was measured in patients receiving a new matrix therapy agent (regenerating agent, Cacicol® ) that mimics heparan sulphates. METHODS: This was a prospective, open-label, uncontrolled, single-centre observational study. A total of 33 consecutive patients (33 eyes) who underwent an 8...
October 31, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30373400/a-novel-missense-mutation-of-gja8-causes-congenital-cataract-in-a-large-mauritanian-family
#11
Mouna Hadrami, Crystel Bonnet, Fatimetou Veten, Christina Zeitz, Christel Condroyer, Panfeng Wang, Mohamed Biya, Med Ahmed Sidi Ahmed, Qingjiong Zhang, Sidi Cheikh, Isabelle Audo, Christine Petit, Ahmed Houmeida
OBJECTIVE OF THE STUDY: Inborn lens opacity is the most frequent cause of childhood blindness. In this study, we aimed to define the presumed genetic cause of a congenital cataract present in a Mauritanian family over the last nine generations. METHODS: A family history of the disease and eye examination were carried out for the family members. Next-generation sequencing using a panel of 116 cataract underlying genes was selectively conducted on the proband's DNA...
October 29, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30360664/platelet-rich-plasma-to-rescue-an-ulcerated-orbital-dermal-fat-graft
#12
Tania Andrea Chaparro Tapias, Alberto Luis Díaz Díaz, Roberto Secondi, Helena Coy Villamil, Juan Carlos Sánchez España
INTRODUCTION: Central graft ulceration is a rare complication of an orbital dermal fat graft caused by diminished blood supply to the implant. This study reports on the efficacy and safety of the use of a single subconjunctival injection of autologous platelet-rich plasma to rescue an ulcerated orbital dermal fat graft. METHODS: Three patients, who had undergone autologous dermal fat graft to treat their anophthalmic socket, were given a 2-mL subconjunctival platelet-rich plasma injection in the exposed graft margins...
October 26, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30360660/automated-gonioscopy-photography-for-iridocorneal-angle-grading
#13
Filipa Teixeira, David C Sousa, Inês Leal, André Barata, Carlos M Neves, Luís A Pinto
PURPOSE: The aim of this study is to assess the agreement between manual and automated gonioscopy for iridocorneal angle opening. METHODS: The research is a cross-sectional observational study. Manual and automated gonioscopy were performed to consecutive patients in a glaucoma clinic. Iridocorneal angle opening grading was performed according to Shaffer's classification. Automated gonioscopy was performed with NGS-1 automated gonioscope (NIDEK Co., Gamagori, Japan)...
October 26, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30360648/factors-affecting-the-motor-outcome-after-corrective-surgery-for-acquired-comitant-esotropia
#14
Rehab R Kassem
PURPOSE: To determine the possible predictors of the motor outcome after corrective surgery for acquired comitant esotropia. METHODS: The study included 40 patients with acquired comitant esotropia. After evaluation of the visual, sensory, and motor status; cycloplegic refraction; fundus examination; and spectacle prescription, all patients underwent corrective strabismus surgery. A successful motor outcome was defined as 0 to 10 prism diopters of horizontal tropia...
October 26, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30354490/non-surgical-management-of-congenital-ichthyosis-using-hyaluronic-acid-gel-injection
#15
Maria Vittoria Cicinelli, Tarjani Vivek Dave, Bejanki Kavya Madhuri, Sweety Tiple, Milind N Naik
AIM: To test if hyaluronic acid gel injection in the upper eyelid achieves correction of congenital cicatricial ectropion and reduction in lagophthalmos, in preparation for intraocular surgery. METHODS: This case reports the long-term outcome of hyaluronic acid gel injection in the upper eyelid for the correction of ectropion prior to cataract surgery. One millilitre of hyaluronic acid gel was injected in both the upper eyelids of a child with congenital ichthyosis in the suborbicularis plane, prior to cataract surgery...
October 25, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30353744/cystic-roof-collapse-after-intravitreal-injection-of-dexamethasone-implant-a-case-report
#16
Francesco Romano, Giorgia Carlotta Albertini, Alessandro Arrigo, Maurizio Battaglia Parodi, Francesco Bandello
INTRODUCTION: Disorders of vitreoretinal interface represent a rare complication of intravitreal dexamethasone implant injection. Our report describes a new mechanism resulting in cystic roof collapse and emphasizes the importance of a strict optical coherence tomography evaluation during therapy with dexamethasone injection in order to prevent this rare complication. PURPOSE: To describe the rupture of the cystic roof following treatment with sustained-release dexamethasone implant intravitreal injection (Ozurdex; Allergan, Irvine) for macular edema...
October 24, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30328376/cutting-the-subconjunctival-fragment-of-the-xen-gel-implant-during-needling-procedure
#17
Youssef Bustros, Ankita Chaudhary, Lauriane Salinas, Kaweh Mansouri
PURPOSE: To describe the case and the follow-up of an inadvertently damaged XEN gel implant during needling procedure. METHODS: Case report. RESULTS: A 60-year-old African American patient underwent an uncomplicated combined phacoemulsification with the insertion of a XEN gel implant. Two months postoperatively, a needling procedure was required. During the needling procedure, a fragment of the XEN gel implant was inadvertently damaged. One month postoperatively, the intraocular pressure was still controlled and the bleb was functioning well...
October 17, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30328359/the-effect-of-tunnel-length-and-position-on-postoperative-corneal-astigmatism-an-optical-coherence-tomographic-study
#18
Serap Sonmez, Cagatay Karaca
PURPOSE: The purpose of this study is to evaluate the effects of variation in tunnel length of same-sized clear corneal phacoemulsification incisions on the generation of surgically induced astigmatism and corneal astigmatism. METHODS: A total of 126 cataract patients treated in four study groups based on location and tunnel length of the clear corneal incisions (superior long, superior short, temporal long, temporal short) were reviewed. In the short tunnel groups, a 2...
October 17, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30318914/bimanual-femtosecond-laser-assisted-cataract-surgery-compared-to-standard-bimanual-phacoemulsification-a-case-control-study
#19
Gian Maria Cavallini, Elisa Fornasari, Michele De Maria, Andrea Lazzerini, Luca Campi, Tommaso Verdina
PURPOSE: To evaluate the efficacy and safety of bimanual, low-energy femtosecond laser-assisted cataract surgery with 1.4-mm microincisions compared to standard bimanual phacoemulsification (bimanual microincision cataract surgery). DESIGN: Prospective, non-randomized comparative case series. METHODS: Bimanual femtosecond laser-assisted cataract surgery with microincisions was performed on 80 eyes (Group A) with the low-energy Ziemer LDV Z8; a matched case-control series of 80 eyes performed with standard bimanual microincision cataract surgery technique was selected for comparison (Group B)...
October 14, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/30318913/use-of-ab-interno-kahook-dual-blade-trabeculectomy-for-treatment-of-primary-congenital-glaucoma
#20
Morgan M Harvey, Joseph W Schmitz
INTRODUCTION: Primary congenital glaucoma is a rare ocular disorder that is responsible for 0.01%-0.04% of total blindness worldwide.1 The goal of congenital glaucoma management is to allow for proper development of the immature visual system by controlling intraocular pressure. Medical therapy usually provides a supportive role to temporarily reduce intraocular pressure, but patients typically require iridocorneal angle surgery to facilitate aqueous humor outflow. In this report, we describe the use of minimally invasive ab interno Kahook Dual Blade trabeculectomy for treatment of primary congenital glaucoma...
October 14, 2018: European Journal of Ophthalmology
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