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European Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28731494/subthreshold-micropulse-laser-reduces-anti-vegf-injection-burden-in-patients-with-diabetic-macular-edema
#1
Elad Moisseiev, Sam Abbassi, Sumeer Thinda, Joseph Yoon, Glenn Yiu, Lawrence S Morse
PURPOSE: To evaluate the efficacy of micropulse laser in the early treatment of diabetic macular edema (DME) and its associated burden of anti-vascular endothelial growth factor (VEGF) injections. METHODS: This retrospective comparative study compared a group of 19 eyes with DME treated with micropulse laser to a matched control group of 19 eyes with DME treated with ranibizumab injections without micropulse laser. Recorded parameters included previous medical and ocular history, previous and subsequent ranibizumab injections administered for DME, visual acuity (VA), central macular thickness throughout the follow-up period, and the occurrence of any complications...
July 20, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708224/carbonic-anhydrase-inhibitor-with-topical-nsaid-therapy-to-manage-cystoid-macular-edema-in-a-case-of-gyrate-atrophy
#2
Elena Piozzi, Salvatore Alessi, Silvia Santambrogio, Giovanni Cillino, Marco Mazza, Aissa Iggui, Salvatore Cillino
PURPOSE: Gyrate atrophy of the choroid and retina (GACR) is a rare chorioretinal dystrophy characterized by a deficiency of the enzyme ornithine aminotransferase, inherited in an autosomal recessive pattern. CASE REPORT: We report a case of a 17-year-old girl with GACR, for whom the level of serum ornithine had been reduced by an arginine-restricted diet. The patient was responsive to an association of topical nonsteroidal anti-inflammatory drugs (NSAIDs) and a carbonic anhydrase inhibitor (CAI) to reduce cystoid macular edema (CME)...
July 8, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708218/microbial-characteristics-of-posttraumatic-infective-keratitis
#3
Blanche X Lim, Victor T C Koh, Manotosh Ray
PURPOSE: To determine the demographics, risk factors, clinical and microbiological characteristics, and treatment outcome of posttraumatic infective keratitis. METHODS: Consecutive patients with posttraumatic infective keratitis presenting to the Ophthalmology Department of a tertiary referral hospital in Singapore between March 2012 and March 2016 were prospectively identified. A standardized data collection form was used to document patient demographics, microbiological diagnosis, antibiotic sensitivity, and pretreatment and posttreatment ocular characteristics...
July 8, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708223/author-s-reply-to-comments-to-povidone-iodine-3-minute-exposure-time-is-viable-in-preparation-for-cataract-surgery
#4
Chu L Nguyen, Lawrence J Oh, Eugene Wong, Ian C Francis
No abstract text is available yet for this article.
July 5, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708222/multimodal-imaging-in-a-patient-with-traumatic-choroidal-ruptures
#5
Luisa Pierro, Chiara Giuffrè, Alessandro Rabiolo, Marco Gagliardi, Alessandro Arrigo, Francesco Bandello
PURPOSE: To describe the case and the follow-up of a traumatic choroidal rupture characterized by means of multimodal imaging including color fundus photographs, infrared reflectance, blue autofluorescence, swept-source optical coherence tomography, fluorescein angiography (FA), indocyanine green angiography (ICGA), and optical coherence tomography angiography (OCT-A). METHODS: Case report. RESULTS: A 17-year-old boy was referred to our clinic complaining of reduction in visual acuity in the right eye (RE) after a blunt ocular trauma during a soccer match...
July 5, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708220/comments-to-povidone-iodine-3-minute-exposure-time-is-viable-in-preparation-for-cataract-surgery
#6
Hiroyuki Shimada, Hiroyuki Nakashizuka, Andrzej Grzybowski
No abstract text is available yet for this article.
July 2, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708221/rapid-response-to-dexamethasone-intravitreal-implant-in-diabetic-macular-edema
#7
Giuseppe Lo Giudice, Antonio Avarello, Gianluca Campana, Alessandro Galan
PURPOSE: To evaluate the early effects of dexamethasone (DEX) intravitreal implants in patients with diabetic macular edema (DME). METHODS: This was a prospective, single-arm, interventional clinical series. Eighteen patients (18 eyes) with chronic/recalcitrant or naive DME were included. Patients underwent single DEX intravitreal implant. Clinical assessments, including ophthalmologic examination, central retinal thickness (CRT) measurement by spectral-domain optical coherence tomography (SD-OCT) scan, best-corrected visual acuity (BCVA), and intraocular pressure (IOP) were carried out at baseline, 1-3 hours, and then 3, 7, and 30 days after treatment...
July 1, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708219/one-year-efficacy-and-safety-of-0-1-cyclosporine-a-cationic-emulsion-in-the-treatment-of-severe-dry-eye-disease
#8
Christophe Baudouin, Maite Sainz de la Maza, Mourad Amrane, Jean-Sébastien Garrigue, Dahlia Ismail, Francisco C Figueiredo, Andrea Leonardi
PURPOSE: The SANSIKA study evaluated the efficacy/safety of 0.1% (1 mg/mL) cyclosporine A cationic emulsion (CsA CE) for treating dry eye disease (DED) with severe keratitis. The double-masked phase demonstrated that CsA CE was effective in reducing corneal damage and ocular surface inflammation, and was well-tolerated over 6 months. Here we report efficacy and safety findings of SANSIKA's open-label extension (OLE). METHODS: In this multicenter, double-masked, phase III study, patients with severe DED (corneal fluorescein staining [CFS] grade 4, modified Oxford scale) were randomized to once-daily CsA CE (Ikervis®) or its vehicle for 6 months, followed by 6-month open-label, once-daily CsA CE (CsA CE/CsA CE and vehicle/CsA CE groups)...
July 1, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28665478/phacoemulsification-outcomes-with-different-illumination-techniques
#9
Juan B Yepez, Felipe A Murati, Félix García, Vivian Calderon, Jazmin Cedeño de Yepez, J Fernando Arévalo
PURPOSE: To compare surgeon experience and the outcomes of phacoemulsification using 2 different illumination techniques for cataract extraction. METHODS: A prospective interventional case series was performed on 20 consecutive patients (20 eyes) with senile cataract who underwent phacoemulsification enhanced with a 23-G endoillumination probe. The main outcome measures were the surgeon's perception of depth of field and quality of visibility of intraocular structures, ease of performance of the surgical procedure, effectiveness, and complications related to the procedure...
June 26, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28665477/visual-acuity-and-image-quality-in-5-diffractive-intraocular-lenses
#10
Genís Cardona, Fidel Vega, Miguel A Gil, Consuelo Varón, José A Buil, María S Millán
PURPOSE: To compare objective image quality at distant, intermediate, and near foci with the corresponding visual acuity (VA) in patients symmetrically implanted with 5 different diffractive multifocal intraocular lenses (IOLs) (ReSTOR SV25T0, Tecnis ZKB00, Tecnis ZLB00, AT LISA 809, and AT LISA Tri 839MP) and a monofocal lens (Tecnis ZA9003) 3 months after cataract intervention. METHODS: Objective image quality, measured as the area under the modulation transfer function curve (AMTF), was tested in vitro in an eye model...
June 26, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28665476/incidence-and-evolution-of-subretinal-precipitates-in-optic-disc-pit-maculopathy
#11
Irini Chatziralli, George Theodossiadis, Dimitrios Brouzas, Panagiotis Theodossiadis
PURPOSE: To study the evolution of subretinal precipitates coexistent with optic disc pit (ODP) maculopathy from their appearance at baseline examination until their absorption after successful treatment. METHODS: Participants in this retrospective, multicenter study were 42 patients with ODP maculopathy, in whom complete ocular examination was performed, including visual acuity (VA) measurement, slit-lamp examination, color or red-free fundus photography, and optical coherence tomography at baseline after surgical treatment...
June 26, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28665475/autologous-cultivated-limbal-stem-cell-transplantation-after-failed-previous-limbal-graft
#12
Karl A Knutsson, Stanislav Matuska, Paolo Rama
PURPOSE: To describe a case of unilateral limbal stem cell deficiency (LSCD) with previously failed autologous graft, resolved by ocular surface reconstruction using cultured autologous limbal stem cells from the contralateral eye. CASE REPORT: A 35-year-old patient presented to our clinic with LSCD due to a unilateral alkali burn. The patient had received a previous limbal graft from the contralateral eye that had failed to impede corneal conjunctivalization. We decided to repeat limbal stem cell transplantation using an ex vivo cultivation procedure to reduce the risk of tissue harvesting on the healthy fellow eye...
June 20, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28665474/evaluation-of-pain-during-intravitreal-aflibercept-injections
#13
Sibel Doguizi, Mehmet A Sekeroglu, Merve Inanc, Mustafa A Anayol, Pelin Yilmazbas
PURPOSE: To evaluate the pain associated with intravitreal aflibercept injections. METHODS: The study included 119 patients who received intravitreal aflibercept injection at a single institution. Pain was evaluated by visual analog scale (VAS) immediately after the injection of 2 mg/0.05 mL aflibercept into the vitreous cavity using a 27-G needle. Additional variables including age, sex, indication for the injection, injection site by quadrant (superotemporal or inferotemporal), position during injection (sitting or supine), number of previous intravitreal injections in the study eye, presence of diabetes mellitus or hypertension, and lens status (phakic or pseudophakic) were recorded and assessed with self-reported pain scores...
June 20, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28623647/expression-of-mtor-in-primary-pterygium-and-its-correlation-with-%C3%AE-smooth-muscle-actin
#14
Xin-Rong Zhao, Ming-Chang Zhang, Hua-Tao Xie, Nan Ji, Xiao-Qiong Ma
PURPOSE: Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase that has been shown to affect many cellular functions, such as cell growth, proliferation, and metabolism. However, there has been minimal focus on the expression of mTOR in pterygium. The purpose of this study was to investigate the expression of mTOR and the correlation between the levels of mTOR and α-smooth muscle actin (α-SMA, a marker of transdifferentiation) in pterygium. METHODS: Primary pterygium samples from 28 patients and normal conjunctival samples from 16 patients were surgically removed and analyzed...
June 14, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604983/visual-outcomes-of-the-second-eye-in-keratoconic-patients-who-have-a-corneal-graft-in-the-first-eye-analysis-at-12-years
#15
Anne-Sophie Gauthier, Marie Friot, Marc Puyraveau, Thibaud Garcin, Maher Saleh, Phillipe Gain, Bernard Delbosc
PURPOSE: To analyze demographic, clinical, and keratometric outcomes of the second eye in keratoconic patients when the first eye has already been grafted, initially and finally at 12 years. METHODS: Retrospective analysis of initial and 12 years visual and keratometric outcomes of the second eye in keratoconic patients when the first one has already been grafted. RESULTS: A total of 107 patients were included: 66 patients were analyzed at the beginning of the follow-up and at 12 years...
June 10, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604980/sealed-implantation-of-foldable-intraocular-lenses
#16
Dharmendra Nath, Eytan Z Blumenthal, Mohita Sharma, Michael Mimouni
PURPOSE: To evaluate the safety and efficacy of sealed implantation, a simple technique for implanting foldable intraocular lenses (IOLs). METHODS: This was a retrospective study including consecutive patients who underwent phacoemulsification cataract using the sealed implantation technique. Sealed implantation is a technique in which a single-piece, foldable IOL is implanted without an intraocular ophthalmic viscosurgical device (OVD) or continuous infusion (hydroimplantation) of balanced saline solution (BSS)...
June 10, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604985/longitudinal-assessment-of-intraocular-pressure-in-premature-infants
#17
Ozlem Balci, Cafer Tanriverdi, Gokhan Gulkilik, Cengiz Aras, Ayhan Tastekin
PURPOSE: To investigate the longitudinal change in intraocular pressure (IOP) in premature infants and to establish a normative IOP value. METHODS: Forty premature infants with a gestational age (GA) of 26 weeks were enrolled in this longitudinal study. Measurements were taken initially at 28 weeks postconceptional age (PCA) and at 2-week intervals up to 40 weeks PCA. Intraocular pressure was measured with a hand-held tonometer (Tono-Pen XL; Reichert Inc.). RESULTS: From 40 (22 male, 18 female) premature Caucasian infants, seven (for each eye) IOP measurements were obtained...
June 9, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604982/edi-oct-evaluation-of-choroidal-thickness-in-retinitis-pigmentosa
#18
Andrea Sodi, Chiara Lenzetti, Vittoria Murro, Orsola Caporossi, Dario P Mucciolo, Daniela Bacherini, Francesca Cipollini, Ilaria Passerini, Gianni Virgili, Stanislao Rizzo
PURPOSE: To evaluate choroidal thickness (CT) in retinitis pigmentosa (RP) using enhanced depth imaging (EDI) optical coherence tomography (OCT). METHODS: A retrospective analysis of a group of patients with RP who underwent EDI-OCT was performed. Choroidal thickness measurements were compared with those of age- and sex-matched healthy subjects. In the RP group, the possible association between subfoveal CT and some clinical parameters (visual acuity, age, age at disease onset, duration of the disease, macular thickness, visual field loss, electroretinography [ERG]) was evaluated...
June 9, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604981/optic-disc-pit-maculopathy-after-prone-positioning-spine-surgery
#19
Marcos Ruiz-Sánchez, Maria E Rodríguez-González-Herrero, Jenifer Ruiz-Sará
PURPOSE: To report a case of optic disc pit maculopathy after spine surgery performed in the prone position. METHODS: Case report. RESULTS: A 32-year-old man underwent spine surgery for disc herniation repair. He complained of visual acuity loss immediately after the procedure. Optic disc maculopathy with internal limiting membrane detachment was found to be the cause. Vitrectomy was scheduled after a 12-month follow-up without resolution of the maculopathy...
June 9, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604984/choroidal-thickness-and-ametropia-in-children-a-longitudinal-study
#20
Marine Fontaine, David Gaucher, Arnaud Sauer, Claude Speeg-Schatz
PURPOSE: To determine the relationship of subfoveal choroidal thickness (ChT), refraction, and axial length in children, and evaluate the evolution of subfoveal ChT with time in myopic versus nonmyopic eyes. METHODS: A total of 229 eyes of 115 children aged 2 to 16 years were included in the study. Refraction under cycloplegia, axial length, and subfoveal ChT were measured at baseline with comparative investigations at 15 months follow-up. RESULTS: The probability for the subfoveal ChT to be thinner in myopic children compared to nonmyopic children was 0...
June 7, 2017: European Journal of Ophthalmology
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