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Minerva Gastroenterologica e Dietologica

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https://www.readbyqxmd.com/read/28673071/lactase-non-persistent-genotype-distribution-in-italy
#1
Cristina Zadro, Savina Dipresa, Giovanni Zorzetti, Annalisa Pediroda, Francesco Menegoni
BACKGROUND: Adult-type hypolactasia is a frequent condition of lactose malabsorption; in Europe the distribution of adult-type hypolactasia have been shown to display a North-South gradient. Genotyping for LCT-13910 C>T polymorphism has been proposed as a useful diagnostic marker of adult-type hypolactasia. Data concerning lactase non-persistent genotype distribution in Italy are confused and not well characterized. The aim of this study was to determine the prevalence of CC-genotype corresponding to lactase non-persistence in Italian population...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28673070/update-in-gastroesophageal-reflux-disease
#2
Vincenzo Savarino
No abstract text is available yet for this article.
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28673069/hepatitis-b-core-related-antigen-a-novel-biomarker-for-chronic-hepatitis-b-treatment
#3
Gian Paolo Caviglia, Antonina Smedile
No abstract text is available yet for this article.
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28497936/grading-health-claims-by-weight-of-evidence-would-make-for-a-better-informed-public
#4
François A Allaert, Jacques Vandermander, Florent Herpin, Gabrielle Ventura
In the European Regulation 1924/2006 and especially its first recital, the evaluation of health claims (HC) by European Food Safety Agency (EFSA) was introduced so as "to ensure a high level of consumer protection, [and] give the consumer the necessary information to make choices in full knowledge of the facts…". Now, with 10 years of hindsight since the Regulation was adopted, it can be asked whether EFSA HC process of evaluation that led to a marginal number of accepted claims is consistent with this objective, not just for protecting consumers but for allowing them to decide freely and make informed choices...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28272380/complexity-and-diversity-of-gastroesophageal-reflux-disease-phenotypes
#5
Patrizia Zentilin, Elisa Marabotto, Gaia Pellegatta, Claudia Coppo, Manuele Furnari, Edoardo Savarino, Vincenzo Savarino
Gastroesophageal reflux disease (GERD) is defined as a condition which develops when the reflux of gastric contents causes troublesome symptoms, impairs quality of life, or leads to mucosal damage or complications. There are two main phenotypic presentations of GERD, the erosive (ERD) and non-erosive reflux disease (NERD), with the latter one representing up to 70% of GERD spectrum. Moreover, patients with GERD can be clinically subdivided into two distinct syndromes: patients with esophageal and extraesophageal symptoms...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28260354/overlap-of-gerd-and-gastrointestinal-functional-disorders
#6
Nicola de Bortoli, Veronica Natali, Sara Melissari, Natalia Simonetti, Gherardo Tapete, Santino Marchi
The functional gastrointestinal disorders (FGIDs) are common conditions with an overall prevalence burden estimated at approximately one-third of the population. These represent a heterogeneous group of conditions which may include both abnormal symptom perception and functional causes and seems to share similar trigger factors as food, lifestyle and psychological factor. GERD develops when the reflux of gastric contents into the esophagus leads to troublesome symptoms, with or without mucosal involvement. Functional heartburn (FH) represents a subcategory of patients who refers with heartburn but without abnormal esophageal acid exposure, abnormal number of reflux events or any temporal correlation between symptoms and reflux events, on the same hands these patients do not report any symptom relief during antisecretory treatment with proton pump inhibitors...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28260353/is-there-a-role-for-high-resolution-manometry-in-gerd-diagnosis
#7
Salvatore Tolone, Edoardo Savarino, Ludovico Docimo
Gastroesophageal reflux disease (GERD) is a condition, which develops when the reflux of stomach contents causes troublesome symptoms and/or complications. In patients with alarm symptoms or signs or in those refractory to antiacid therapy, it is indicated to perform instrumental tests to correctly diagnose GERD presence. Esophageal manometry is currently considered the gold standard test for the diagnosis of esophageal dysmotility. However, it has shown limited capability in diagnosing GERD. With the advent of high resolution manometry (HRM), more accurate evaluations of esophageal motility are now possible...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28260352/extra-esophageal-presentation-of-gastroesophageal-reflux-disease-new-understanding-in-a-new-era
#8
Irene Martinucci, Eleonora Albano, Santino Marchi, Corrado Blandizzi
Associations of gastroesophageal reflux disease (GERD) with extraesophageal manifestations, such as chronic cough, asthma, and laryngitis, are reported frequently, and there is a strong evidence of biological plausibility in support of this relationship. On the other hand, extraesophageal reflux disease (EERD) is usually multifactorial in nature with reflux being just one of the several potential contributing cofactors. Moreover, the accuracy of currently available diagnostic tests for EERD is suboptimal, and therefore the causal relationship between GERD and EERD remains far from being conclusively proven...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28251845/proton-pump-inhibitor-refractory-gastroesophageal-reflux-disease-current-diagnosis-and-management
#9
Leonardo Frazzoni, Lorenzo Fuccio, Marzio Frazzoni
Proton pump inhibitor (PPI) therapy is the mainstay of treatment for gastroesophageal reflux disease (GERD). However, up to 30% of patients with reflux symptoms report inadequate symptom control with PPI therapy. PPI-refractory GERD should be suspected when troublesome reflux symptoms persist after 4-week standard dosage and 8-week high-dosage PPI therapy. Impedance-pH monitoring represents the gold standard for investigating the mechanism(s) of PPI refractoriness and for distinguishing patients with reflux-related from those with reflux-unrelated PPI-refractory syndromes...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28251844/overview-of-pathophysiological-features-of-gerd
#10
Paolo Usai Satta, Francesco Oppia, Francesco Cabras
Gastroesophageal reflux disease (GERD) is a very prevalent condition and has a high impact on the quality of life. Nevertheless, pathophysiology is complex and multi-factorial. Several mechanisms have been proposed: decreased salivation, decreased lower esophageal sphincter pressure resting tone, presence of hiatal hernia, increased number of transient lower esophageal sphincter relaxations, increased acid, and pepsin secretion, duodeno-gastro-esophageal reflux of bile acids and trypsin. Other factors contributing to the pathophysiology of GERD include poor esophageal clearance, delayed gastric emptying and impaired mucosal defensive factors...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28215067/epidemiology-and-natural-history-of-gastroesophageal-reflux-disease
#11
Edoardo Savarino, Elisa Marabotto, Giorgia Bodini, Gaia Pellegatta, Claudia Coppo, Elisa Giambruno, Matteo Brunacci, Patrizia Zentilin, Vincenzo Savarino
Gastroesophageal reflux disease (GERD) is highly prevalent in Western countries, particularly when considering its most classic symptom that is heartburn. This symptom is very frequent in the community and ranges from 10% to more than 30%, according to the various population-based studies. This disease is much more represented in Europe and USA than in Asiatic countries. It has been shown that GERD prevalence increases in parallel with the remarkable growth of obesity, as this condition is able to favor all the pathogenetic mechanisms leading to it...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28185444/effect-of-cis-palmitoleic-acid-supplementation-on-inflammation-and-expression-of-hnf4%C3%AE-hnf4%C3%AE-and-il6-in-patients-with-ulcerative-colitis
#12
Nallely Bueno-Hernández, María S Sixtos-Alonso, María Del Pilar Milke García, Jesús K Yamamoto-Furusho
BACKGROUND: Cis-palmitoleic acid (Omega-7 fatty acid) is a monounsaturated fatty acid (MUFA) associated with anti-inflammatory process through specific protein interactions such as HNF4γ and HNF4α, these two genes are related to the immune response in ulcerative colitis (UC) they may act as a mediator of anti-inflammatory action. The aim of this study was to evaluate the effect of Cis-palmitoleic acid supplementation on inflammatory activity and the expression of genes HNF4γ, HNF4α and IL6 in the colonic mucosa of patients with active UC...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28079345/towards-reducing-the-risk-of-new-onset-diabetes-after-pancreatitis
#13
Chirag J Jivanji, Danielle H Soo, Maxim S Petrov
Metabolic abnormalities due to acute and chronic pancreatitis are common. In particular, post-pancreatitis diabetes mellitus (PPDM) is increasingly recognized as a distinct clinical entity. However, most of the research in this field is focused on unravelling the pathogenesis of PPDM whereas research frontiers are rarely extended to reducing the risk of new onset diabetes after pancreatitis (NODAP). The recent development and validation of the PERSEUS score paved the way to identifying individuals after acute pancreatitis who are at high risk of developing NODAP...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27905696/the-curative-effect-of-early-use-of-enteral-immunonutrition-in-postoperative-gastric-cancer-a-meta-analysis
#14
Hu Qiang, Lu Hang, Sun Y Shui
INTRODUCTION: The clinical efficacy of early enteral immunonutrition in postoperative gastric cancer patients is uncertain. The aim of this study is to assess its clinical efficacy. EVIDENCE ACQUISITION: Use of the search engine database incuding the PubMed, the Cochrane library, Web of Science, Medline, and Embase, which present comparative studies of early efficacy of enteral immune nutrition and standard enteral nutrition after gastric cancer operation. We used the RevMan 5...
September 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391677/moxifloxacin-but-not-metronidazole-can-be-used-in-therapeutic-regimens-against-helicobacter-pylori
#15
Amin Talebi Bezmin Abadi, Shakiba Shafahi Tilaki, Golzar Fattahi, Sakineh Safarnejad
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391676/malignant-gastrocolic-fistula-diagnosed-by-esophagogastroduodenoscopy-and-colonoscopy
#16
Molly Orosey, Tusar Desai, Mitual Amin, Mitchell S Cappell
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391675/effect-of-morning-vs-afternoon-scheduling-of-endoscopic-us-guided-fna-on-outcomes-of-solid-pancreatic-lesions
#17
Gustavo Gomez, Shailendra Singh, Vamsi Kantamaneni, Pavithra Indramohan, Mohammad Bilal, Suzanne Morrissey, Shyam Thakkar, Heitham Abdul-Baki, Manish Dhawan
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391674/diverticular-disease-myths-and-facts
#18
Bruno Annibale
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28240005/surgery-for-diverticulitis-in-the-21st-century-recent-evidence
#19
Arden M Morris, Cindy Kin
Sigmoid diverticulitis is an increasingly common disease in Western countries. As technology has led to increased knowledge about the disease and options for treatment, management strategies have become less certain. In previous years, the rationale for early elective surgery was largely preventive, due to concern that diverticulitis recurrence would result in increased risk of sepsis or the need for a colostomy. New technology has enabled diagnosis, through computed tomography scans, predictive information through clinical and administrative databases, and less invasive treatment options, through laparoscopic techniques...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28240003/natural-history-of-bleeding-risk-in-colonic-diverticulosis
#20
Lior Segev, Gokhan Ozuner
Colonic diverticulosis prevalence is gradually increasing worldwide. From 3% to 15% of the patients with diverticulosis will bleed at some point. The risk for rebleeding after the first episode is substantial but varies in the literature between 13-48%. We analyzed risk factors for diverticular bleed and management options for initial and recurrent diverticular bleeding. A review of the literature on this subject is presented.
June 2017: Minerva Gastroenterologica e Dietologica
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