Matteo Ghisa, Giorgio Laserra, Daria Maniero, Elisa Marabotto, Brigida Barberio, Filippo Pelizzaro, Ilenia Barbuscio, Fabiana Zingone, Vincenzo Savarino, Edoardo Savarino
EoE incidence and prevalence have sharply increased in the last decade and management of these patients is changing rapidly. Standard regimens as elimination diet, proton pump inhibitors and topical swallowed steroids are not able to achieve remission in all patients. Moreover, loss of efficacy and safety concerns for long-term medical treatments are rising questions. As for other chronic immune-mediated diseases, biologics have been evaluated for treatment of EoE. Several targets in the Th2-mediated inflammatory cascade with eosinophilic mucosal infiltration, have been tested with alternating results...
December 3, 2020: Minerva Gastroenterologica e Dietologica