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Minerva Gastroenterologica e Dietologica

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https://www.readbyqxmd.com/read/28497936/grading-health-claims-by-weight-of-evidence-would-make-for-a-better-informed-public
#1
François A Allaert, Jacques Vandermander, Florent Herpin, Gabrielle Ventura
In the European Regulation 1924/2006 (1) and especially its first recital; the evaluation of health claims (HC) by European Food Safety Agency (EFSA) was introduced so as "to ensure a high level of consumer protection, [and] give the consumer the necessary information to make choices in full knowledge of the facts…" Now, with 10 years of hindsight since the Regulation was adopted, it can be asked whether EFSA HC process of evaluation that led to a marginal number of accepted claims is consistent with this objective, not just for protecting consumers but for allowing them to decide freely and make informed choices...
May 10, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28398025/hepatocarcinoma-genetic-and-epigenetic-features
#2
Angela Lombardi, Anna Grimaldi, Silvia Zappavigna, Gabriella Misso, Michele Caraglia
HCC is the third leading cause of cancer-related deaths worldwide, accounting for about 1 million deaths annually. The incidence of HCC is highest in Asia and Africa, where the endemic high prevalence of hepatitis B and hepatitis C strongly predisposes to the development of chronic liver disease and subsequent development of HCC. Patients with HCC generally present at an advanced stage due to compensated cirrhosis defined by the absence of pathognomonic symptoms, resulting in death within 6 to 20 months, suggesting an urgent need in treatment modalities that will dramatically decrease the mortality rate of HCC...
April 11, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28397484/gut-microbiota-and-gastrointestinal-tract-liver-and-pancreas-from-physiology-to-pathology
#3
Carmela Loguercio
No abstract text is available yet for this article.
April 7, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28381083/the-gut-microbiota-its-anatomy-and-physiology-during-all-life
#4
Giulia Gibiino, Gianluca Ianiro, Giovanni Cammarota, Antonio Gasbarrini
The wide assemblage of microorganisms inhabiting our gastrointestinal tract is an attractive field for overwhelming contemporary research in several aspects of the human health. Most recent molecular techniques, as the use of rRNAs or whole genome sequencing, definitely overcame traditional culture techniques in giving outline of the intestinal bacterial richness. Moreover, the crosstalk between host and intestinal microbes is considered a cornerstone affecting the host's metabolism, immunity, autoimmunity and autoinflammation and elaborate networks linked to several organs...
April 4, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391677/moxifloxacin-but-not-metronidazole-can-be-used-in-therapeutic-regimens-against-helicobacter-pylori
#5
Amin Talebi Bezmin Abadi, Shakiba Shafahi Tilaki, Golzar Fattahi, Sakineh Safarnejad
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391676/malignant-gastrocolic-fistula-diagnosed-by-esophagogastroduodenoscopy-and-colonoscopy
#6
Molly Orosey, Tusar Desai, Mitual Amin, Mitchell S Cappell
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391675/effect-of-morning-vs-afternoon-scheduling-of-endoscopic-us-guided-fna-on-outcomes-of-solid-pancreatic-lesions
#7
Gustavo Gomez, Shailendra Singh, Vamsi Kantamaneni, Pavithra Indramohan, Mohammad Bilal, Suzanne Morrissey, Shyam Thakkar, Heitham Abdul-Baki, Manish Dhawan
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28391674/diverticular-disease-myths-and-facts
#8
Bruno Annibale
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28240005/surgery-for-diverticulitis-in-the-21st-century-recent-evidence
#9
Arden M Morris, Cindy Kin
Sigmoid diverticulitis is an increasingly common disease in Western countries. As technology has led to increased knowledge about the disease and options for treatment, management strategies have become less certain. In previous years, the rationale for early elective surgery was largely preventive, due to concern that diverticulitis recurrence would result in increased risk of sepsis or the need for a colostomy. New technology has enabled diagnosis, through computed tomography scans, predictive information through clinical and administrative databases, and less invasive treatment options, through laparoscopic techniques...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28240003/natural-history-of-bleeding-risk-in-colonic-diverticulosis
#10
Lior Segev, Gokhan Ozuner
Colonic diverticulosis prevalence is gradually increasing worldwide. From 3% to 15% of the patients with diverticulosis will bleed at some point. The risk for rebleeding after the first episode is substantial but varies in the literature between 13-48%. We analyzed risk factors for diverticular bleed and management options for initial and recurrent diverticular bleeding. A review of the literature on this subject is presented.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28150481/lifestyle-and-other-risk-factors-for-diverticulitis
#11
Stephan K Böhm, Wolfgang Kruis
Diverticulosis is a very common condition. Around 20% of the carriers of diverticula are believed to suffer from diverticular disease during their lifetime. This makes diverticular disease one of the clinically and economically most significant diseases in gastroenterology. The etiopathogenesis of diverticulosis and diverticular disease is not well understood. Epidemiological studies allow defining risk factors for the development of diverticulitis and its complications. A comprehensive literature search was performed and the current knowledge about risk factors for diverticulitis and associated conditions reviewed...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28150480/adequate-dietary-fiber-supplement-and-tone-can-help-avoid-surgery-in-most-patients-with-advanced-hemorrhoids
#12
Pankaj Garg, Pratiksha Singh
BACKGROUND: The root cause of hemorrhoids resides in three deranged defecation habits (DDH), namely increased straining, prolonged defecation-time, and frequent bowel-motions. These DDH are responsible for the development of new hemorrhoids, progression of existing one and hemorrhoidal rupture (bleeding). DDH can be corrected with the help of the "TONE" mnemonic. TONE entails specifying exact treatment goals: T, three minutes at defecation; O, once-a-day defecation frequency; N, no straining during passing motions; E, enough fiber...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28150479/the-intestinal-mycobiota-a-year-of-observation-about-the-incidence-of-yeast-s-isolation-in-fecal-samples
#13
Lucia Barcella, Santa B Rogolino, Angelo P Barbaro
BACKGROUND: Yeast's presence, especially Candida's species, in the intestinal tract is now considered as part of the normal microbial human flora; however, fungal colonization of the colon may induce to fungal infections, becoming a risk not only in immunocompromised patients but also in normalcompetent subjects. The purpose of this epidemiological study was to evaluate the real incidence of yeasts into the fecal samples both from healthy outpatients and from inpatients, except those from wards concerning immunosuppressive and pediatrics pathologies...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28079347/diagnostic-challenges-of-symptomatic-uncomplicated-diverticular-disease
#14
Cesare Cremon, Lara Bellacosa, Maria R Barbaro, Rosanna F Cogliandro, Vincenzo Stanghellini, Giovanni Barbara
Colonic diverticulosis is a common condition in Western industrialized countries occurring in up to 65% of people over the age of 60 years. Only a minority of these subjects (about 10-25%) experience symptoms, fulfilling Rome III Diagnostic Criteria for irritable bowel syndrome (IBS) diagnosis (IBS-like symptoms) in 10% to 66% of cases. Symptomatic uncomplicated diverticular disease (SUDD) is a syndrome characterized by recurrent abdominal symptoms attributed to diverticula in the absence of macroscopically evident alterations other than the presence of diverticula...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28079346/increasing-role-for-modified-bismuth-containing-quadruple-therapies-for-helicobacter-pylori-eradication
#15
David Y Graham, Sharmila Fagoonee, Rinaldo Pellicano
No abstract text is available yet for this article.
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27990793/therapeutic-management-of-acute-uncomplicated-diverticulitis
#16
Y Claire Fan, Anne F Peery
Acute diverticulitis is a painful disease of the colon characterized by peridiverticular inflammation and/or infection. The spectrum of acute diverticulitis ranges from isolated peridiverticular inflammation all the way to free perforation with purulent or feculent peritonitis. Among gastrointestinal disorders, acute diverticulitis is one of the most common diagnoses in the ambulatory setting and principal hospital discharge diagnoses. Acute diverticulitis accounts for substantial utilization of healthcare resources and is a detriment to patients' quality of life...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27973464/pathogenesis-of-diverticulosis-and-diverticular-disease
#17
Marjorie M Walker, Angela K Harris
Diverticulosis is defined by the presence of diverticula due to herniation of mucosa and muscularis mucosa through the muscularis propria at sites of vascular penetration in the colon and is asymptomatic in the vast majority affected. There are global differences of distribution, in Western industrialized societies, the most common site is in the left colon, but in Asia right sided diverticulosis predominates. Whilst present in 17.5% of a general population and 42% of all comers at endoscopy it is seen in 71% of those aged ≥80 years...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27973463/rationale-and-evidences-for-treatment-of-symptomatic-uncomplicated-diverticular-disease
#18
Rosario Cuomo, Martina Cargiolli, Paolo Andreozzi, Francesco P Zito, Giovanni Sarnelli
INTRODUCTION: Symptomatic uncomplicated diverticular disease (SUDD) is one of the possible clinical manifestations of diverticular disease. It is a common disorder characterized by chronic abdominal symptoms ranging from lower left abdominal pain to alteration of bowel habit, that significantly reduce quality of life of subject affected. The present article aims to review the current data for medical management of SUDD. EVIDENCE ACQUISITION: We analyzed the existing literature on the factors involved in the pathogenesis of SUDD and we highlighted the possible target for treatment...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27973462/bismuth-based-quadruple-therapy-modified-with-moxifloxacin-for-helicobacter-pylori-eradication
#19
Marinko Marušić, Lucija Dominković, Karolina Majstorović Barać, Saša Gulić, Josip Bago, Davorin Pezerović
BACKGROUND: The aim of this study was to evaluate the efficacy, tolerability and safety of modified bismuth-based quadruple therapy for the second-line eradication treatment of Helicobacter pylori (H. pylori) infection. METHODS: Out of 758 patients treated between January 2010 and December 2015, 155 patients (20.45%) remained H. pylori positive after the first line treatment and received the second-line treatment consisting of colloidal bismuth subcitrate (240 mg twice daily), pantoprazole (40 mg twice daily), metronidazole (500 mg twice daily) and moxifloxacin (400 mg once daily) for 14 days...
June 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28293938/effectiveness-and-safety-of-infliximab-biosimilar-ct-p13-in-treating-ulcerative-colitis-a-real-life-experience-in-ibd-primary-centers
#20
Antonio Tursi, Leonardo Allegretta, Stefania Chiri, Nicola Della Valle, Walter Elisei, Giacomo Forti, Roberto Lorenzetti, Giammarco Mocci, Antonio Penna, Giuseppe Pranzo, Cristina Ricciardelli, Marcello Picchio
BACKGROUND: To assess the efficacy and safety of biosimilar infliximab (IFX) IFX CT-P13 in inducing and maintain remission in Ulcerative Colitis (UC) outpatients in Italian primary gastroenterology centers. METHODS: Patients were prospectively assessed at entry, after 8, 12, 24, 36, and therefore 52 weeks. Clinical activity was scored according to the Mayo score. The primary endpoint was reaching of clinical remission (Mayo score ≤2). Several secondary endpoints were clinical response to treatment, reaching of mucosal healing (MH), safety of the drug...
March 14, 2017: Minerva Gastroenterologica e Dietologica
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