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Minerva Gastroenterologica e Dietologica

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https://www.readbyqxmd.com/read/28079347/the-diagnostic-challenge-of-symptomatic-uncomplicated-diverticular-disease
#1
Cesare Cremon, Lara Bellacosa, Maria R Barbaro, Rosanna F Cogliandro, Vincenzo Stanghellini, Giovanni Barbara
Colonic diverticulosis is a common condition in Western industrialized countries occurring in up to 65% of people over the age of 60 years. Only a minority of these subjects (about 10- 25%) experience symptoms, fulfilling Rome criteria for irritable bowel syndrome (IBS) diagnosis (IBS-like symptoms) in 10 to 66% of cases. Symptomatic uncomplicated diverticular disease (SUDD) is a syndrome characterized by recurrent abdominal symptoms attributed to diverticula in the absence of macroscopically evident alterations other than the presence of diverticula...
January 12, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28079346/increasing-role-for-modified-bismuth-containing-quadruple-therapies-for-helicobacter-pylori-eradication
#2
David Y Graham, Sharmila Fagoonee, Rinaldo Pellicano
No abstract text is available yet for this article.
January 12, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28079345/towards-reducing-the-risk-of-new-onset-diabetes-after-pancreatitis
#3
Chirag J Jivanji, Danielle H Soo, Maxim S Petrov
Metabolic abnormalities due to acute and chronic pancreatitis are common. In particular, post-pancreatitis diabetes mellitus (PPDM) is increasingly recognised as a distinct clinical entity. However, most of research in this field is focused on unravelling the pathogenesis of PPDM whereas research frontiers are rarely extended to reducing the risk of new onset diabetes after pancreatitis (NODAP). The recent development and validation of the PERSEUS score paved the way to identifying individuals after acute pancreatitis who are at high risk of developing NODAP...
January 12, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27990793/therapeutic-management-of-acute-uncomplicated-diverticulitis
#4
Y Claire Fan, Anne F Peery
Acute diverticulitis is a painful disease of the colon characterized by peridiverticular inflammation and/or infection. The spectrum of acute diverticulitis ranges from isolated peridiverticular inflammation all the way to free perforation with purulent or feculent peritonitis. Among gastrointestinal disorders, acute diverticulitis is one of the most common diagnoses in the ambulatory setting and principal hospital discharge diagnoses. Acute diverticulitis accounts for substantial utilization of healthcare resources and is a detriment to patients' quality of life...
December 16, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27973464/pathogenesis-of-diverticulosis-and-diverticular-disease
#5
Marjorie M Walker, Angela K Harris
Diverticulosis is defined by the presence of diverticula due to herniation of mucosa and muscularis mucosa through the muscularis propria at sites of vascular penetration in the colon and is asymptomatic in the vast majority affected. There are global differences of distribution, in Western industrialised societies, the most common site is in the right colon, but in Asia left sided diverticulosis predominates. Whilst present in 17.5% of a general population and 42% of all comers at endoscopy it is seen in 71% of those aged ≥80 years...
December 14, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27973463/rationale-and-evidences-for-treatment-of-symptomatic-uncomplicated-diverticular-disease
#6
Rosario Cuomo, Martina Cargiolli, Paolo Andreozzi, Francesco P Zito, Giovanni Sarnelli
INTRODUCTION: Symptomatic uncomplicated diverticular disease (SUDD) is one of the possible clinical manifestations of diverticular disease. It is a common disorder characterized by chronic abdominal symptoms ranging from lower left abdominal pain to alteration of bowel habit, that significantly reduce quality of life of subject affected. The present article aims to review the current data for medical management of SUDD. EVIDENCE ACQUISITION: We analyzed the existing literature on the factors involved in the pathogenesis of SUDD and we highlighted the possible target for treatment...
December 14, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27973462/bismuth-based-quadruple-therapy-modified-with-moxifloxacin-for-helicobacter-pylori-eradication
#7
Marinko Marušić, Lucija Dominković, Karolina Majstorović Barać, Saša Gulić, Josip Bago, Davorin Pezerović
BACKGROUND: To evaluate the efficacy, tolerability and safety of modified bismuth-based quadruple therapy for the second-line eradication treatment of Helicobacter pylori (H. pylori) infection. METHODS: Out of 758 patients treated between January 2010 and December 2015, 155 patients (20.45%) remained H. pylori positive after the first line treatment and received the second-line treatment consisting of colloidal bismuth subcitrate (240 mg twice daily), pantoprazole (40 mg twice daily), metronidazole (500 mg twice daily) and moxifloxacin (400 mg once daily) for 14 days...
December 14, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27905696/the-curative-effect-of-early-use-of-enteral-immunonutrition-in-postoperative-gastric-cancer-a-meta-analysis
#8
Hu Qiang, Lu Hang, Sun Y Shui
INTRODUCTION: It's uncertain about the clinical efficacy which early enteral immunonutrition in postoperative gastric cancer patients,and this study attempts to assess its clinical efficacy. EVIDENCE ACQUISITION: Use the search engine database incuding the Pubmed,the Cochrane library, Web of Science, Medline,and Embase,which there are comparative studies of early efficacy of enteral immune nutrition and standard enteral nutrition after gastric cancer operation.According to the studies,we use the RevMan 5...
December 1, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27849120/review-gut-microbiota-and-functional-diseases-of-the-gastrointestinal-tract
#9
Nicola Imperatore, Raffaella Tortora, Filomena Morisco, Nicola Caporaso
INTRODUCTION: Functional gastrointestinal disorders (FGIDs) are a common group of chronic gastrointestinal (GI) diseases defined by symptom-based diagnostic criteria, which consider chronic or recurrent symptoms of the GI tract in the absence of other organic or biochemical reasons. Recent evidences have been highlighted the role of gut microbiota in the pathophysiology of the FGIDs. EVIDENCE ACQUISITION: We focused our attention on critically analysis of the existing literature on the role of gut microbiota in FGIDs, by evaluating the differences of composition, functions and role of intestinal flora in FGIDs of the upper and lower gastrointestinal tract...
November 16, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27845509/anti-gliadin-antibodies-in-ncgs
#10
Maria Infantino, Francesca Meacci, Valentina Grossi, Donatella Macchia, Mariangela Manfredi
Although no biomarker has been identified to date, previous studies have reported that about 50% of patients with suspected Non Celiac Gluten Sensitivity (NCGS) had positive first generation anti- gliadin antibodies (AGAs), expecially of the IgG class. These antibodies are not specific for NCGS, being also found in CD (80-90%), autoimmune liver disorders (21.5%), connective tissue disease (9%) and IBS (20%), as well as in healthy controls (2-8%), but their finding in patients with a clinical phenotype consistent with NCGS has been regarded as an element supporting this diagnosis...
November 15, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27845508/may-radiofrequency-be-the-best-choice-for-iii-iv-degree-hemorrhoids-results-of-a-large-series-of-patients
#11
Giovanni Milito, Giorgio Lisi, Elena Aronadio, Michela Campanelli, Dario Venditti, Simona Grande, Michele Grande
BACKGROUND: Haemorrhoidectomy is considered the most efficient method to treat haemorrhoids of III and IV grades. The aim of this study is to compare conventional diathermy haemorrhoidectomy and radiofrequency haemorrhoidectomy based on a large series of patients. METHODS: Between June 2001 and June 2014, 1000 patients have been treated with radiofrequency haemorrhoidectomy (Group A) and 500 patients have been treated with diathermy (Group B) as a day-case procedure...
November 15, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27824245/liver-transplantation-from-hcv-rna-positive-donors-in-the-era-of-interferon-free-hcv-therapeutics-a-reexamination-of-the-situation
#12
Katharina Willuweit, Ali Canbay, Guido Gerken, Jörg Timm, Andreas Paul, Jürgen Treckmann, Kerstin Herzer
Although the availability of donor organs is limited, liver grafts from HCV-positive donors remained yet an obstacle, primarily because of limited therapeutic options for HCV reinfection and lower rates of graft and patient survival. However, new interferon-free regimens containing direct-acting antiviral agents have fewer adverse effects and better effectiveness, making HCV treatment feasible early after transplant. In 2014, we successfully used sofosbuvir and ribavirin to treat a patient with HCV genotype 3 cirrhosis who was listed for liver transplantation...
November 8, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27824244/a-large-multicenter-study-of-recurrence-after-surgical-resection-of-branch-duct-intraductal-papillary-mucinous-neoplasm-of-the-pancreas
#13
Linda Yan, Ali A Siddiqui, Sobia Laique, Monica Saumoy, Michel Kahaleh, Joseph Yoo, Ankush Kalra, Arun Mathew, Jessica Sterling, Rema Rao, Michael Lieberman, Natalie Cosgrove
BACKGROUND: Surgery for pancreatic branch-duct intraductal papillary mucinous neoplasm (BDIPMN) is indicated for therapy of symptomatic patients and to prevent development of invasive cancer. There is currently no consensus on management of BD-IPMN patients after surgical resection. The aim of this retrospective multicenter study was to determine the recurrence and long-term survival after surgical resection of BD-IPMN and to determine the predictive factors of recurrence. METHODS: All patients who underwent surgery for BD-IPMN from 2005 to 2011 at 2 centers were identified...
November 8, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27808487/pathophysiology-of-non-celiac-gluten-sensitivity-where-are-we-now-in-2016
#14
Giacomo Caio, Gabriele Riegler, Marta Patturelli, Angela Facchiano, Laura DE Magistris, Anna Sapone
Non-celiac gluten sensitivity (NCGS) is the term used to describe individuals complaining of intestinal and extra-intestinal symptoms related to gluten ingestion and rapidly improving after its withdrawal, and in which both celiac disease (CD) and wheat allergy (WA) were properly ruled out. The prevalence of this condition remains unknown and a lot of questions about the possible pathogenetic mechanisms are still unclarified. It is believed that NCGS represents a heterogeneous condition with different subgroups potentially characterized by different pathogenesis, clinical history, and clinical course...
November 3, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27792210/animal-models-to-study-non-celiac-gluten-sensitivity
#15
Plaimein Amnuaycheewa, Joseph A Murray, Eric V Marietta
Non-celiac gluten sensitivity (NCGS), sometimes known as non-celiac wheat sensitivity (NCWS), has recently received much attention, both scientific as well as from the alternative medical community. Over the past 5 years, there are over 200 publications on NCGS indexed on PubMed database, the gluten-free market has been growing bigger, and it is clear that the number of consumers who are on a gluten-free diet (GFD) possibly because of a suspicion for NCGS appears to grow even faster. Nevertheless, despite these three rising events, many questions about NCGS remain unresolved...
October 28, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28054479/persistent-risk-for-hepatocellular-carcinoma-after-more-than-a-decade-of-successful-hepatitis-b-virus-suppression
#16
Andrew Dargan, She Y Wong, Robert Coben, Mitchell Conn, Anthony J Dimarino, Hie W Hann
No abstract text is available yet for this article.
March 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28054478/world-epidemiology-of-non-celiac-gluten-sensitivity
#17
Brintha Vasagar, Jessica Cox, John T Herion, Erin Ivanoff
While the term "gluten" has become commonplace, the disorders associated with gluten still remain poorly understood. Non-celiac gluten sensitivity (NCGS), the most recently recognized of the gluten-related disorders, is arguably the most unknown. While celiac disease and wheat allergy have diagnostic algorithm, NCGS remains a diagnosis of exclusion. With no evidence-based objective diagnostic criteria or serological tests, it is difficult to diagnose and even more difficult to study epidemiologically. Studies often use varied definitions of NCGS and are difficult to compare or validate...
March 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27763575/optimal-treatment-of-hepatic-encephalopathy
#18
Sanath Allampati, Kevin D Mullen
Hepatic encephalopathy (HE) is a complex neuropsychiatric syndrome associated with decompensated liver disease. The spectrum of disease ranges from trivial abnormalities in complex decision-making and prolonged reaction time to coma in its most severe form. The very initial stages, recently termed covert hepatic encephalopathy, can only be diagnosed with the help of neuropsychiatric testing, while the later and more severe forms, termed overt hepatic encephalopathy, can be diagnosed clinically. Management of HE is very critical as it can dramatically increase morbidity and mortality...
December 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27681222/stereotactic-radiation-therapy-for-hepatic-malignancies
#19
Jeffrey Meyer
Management of primary and secondary tumors of the liver is a complex undertaking involving multi‑disciplinary input. Radiation therapy has played a relatively marginal role in the treatment of liver tumors, but with technological innovations and the growth of the field of stereotactic body radiation therapy (SBRT), this role is evolving. In this review, I discuss the issues of radiation‑induced hepatic toxicity, the planning of liver SBRT treatments, clinical results with SBRT, its place amongst other non‑surgical ablative treatments, and potential future avenues of investigation...
December 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27652683/endoscopic-resection-for-patients-with-mucosal-adenocarcinoma-of-the-esophagus
#20
Mate Knabe, Andrea May, Christian Ell
Due to its rapidly increasing incidence in the last decade, esophageal adenocarcinoma has been attracting widespread interest among gastroenterologists all over the world. Advanced adenocarcinomas arising from intestinal metaplasia in the esophagus (Barrett's esophagus, BE) are associated with a poor prognosis when esophagectomy is required. In addition to high mortality rates, there is a significant morbidity rate among patients who undergo surgery. However, if cancer can be diagnosed at an early stage, the endoscopic treatment options that are available significantly reduce the mortality rates...
December 2016: Minerva Gastroenterologica e Dietologica
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