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Minerva Gastroenterologica e Dietologica

Davide G Ribaldone, Andrea Resegotti, Marco Astegiano
No abstract text is available yet for this article.
January 4, 2019: Minerva Gastroenterologica e Dietologica
Beniamino Palmieri, Maria Vadala', Carmen Laurino
A gluten-free diet is the safest treatment for the treatment of patient with celiac disease (CD) and other gluten-related disorders. However, in the last years, gluten-free diet is one of the most popular diet followed by the general population and by patients affected from others clinical conditions, such as non-celiac gluten sensitivity (NCGS), irritable bowel syndrome (IBS), autism, neurological, psychiatric and rheumatologic diseases and for improving sports practice. This review highlights some questions about the appropriateness of follow this trend answering to some questions such as how safe are the current gluten-free products, what are the benefits and side effects of gluten-free diet and what are clinical conditions that might benefit from gluten avoidance...
December 14, 2018: Minerva Gastroenterologica e Dietologica
Daryl Ramai, Andrew Ofosu, Jameel Singh, Febin John, Madhavi Reddy, Douglas Adler
INTRODUCTION: Ampullary cancer accounts for only 0.2% of GI cancers. The objective of this study was to investigate the incidence, demographics, tumor characteristics, treatment, and survival of patients with ampullary tumors. METHODS: Data on ampullary cancer between 2004 and 2013 was extracted from the Surveillance, Epidemiology and End Results (SEER) Registry. The clinical epidemiology of these tumors was analyzed using SEER*Stat. RESULTS: A total of 6803 patients with ampullary cancer were identified...
November 27, 2018: Minerva Gastroenterologica e Dietologica
Andrew Ofosu, Daryl Ramai, Febin John, Madhavi Reddy, Douglas G Adler
No abstract text is available yet for this article.
November 27, 2018: Minerva Gastroenterologica e Dietologica
Michael P Hunter, Nigel J Crowther
BACKGROUND: The aim of the study was to determine the prevalence of gastroesophageal reflux disease (GORD) in a black population in South Africa and to determine if there was any association with obesity. METHODS: A sample of 312 black subjects was randomly selected and interviewed with a structured questionnaire (GerdQ) consisting of six questions translated into English and two of the most commonly used African languages (Zulu and Xhosa). This question-based symptom score for the diagnosis of GORD has been validated previously...
November 27, 2018: Minerva Gastroenterologica e Dietologica
Elena Mosso, Valentina Boano, Mario Grassini, Edda Battaglia, Rinaldo Pellicano
Microscopic colitis (MC) is diagnosed in presence of microscopic alterations of colonic mucosa, in patients without macroscopic lesions who referred for chronic diarrhea. The two types of MC are lymphocytic colitis (LC) and collagenous colitis (CC), but it is unclear whether these are the different expression of one unique disease or if they are distinct conditions. Today, although MC represents a consistent health problem, being responsible for a large part of gastroenterological consultations for diarrhea, it remains often underestimated...
November 21, 2018: Minerva Gastroenterologica e Dietologica
Andrew Ofosu, Daryl Ramai, Febin John, Mohammed Barakat, Tagore Sunkara, Santosh Sharma, Vinaya Gaduputi, Douglas Adler, Madhavi Reddy
INTRODUCTION: Endoscopic hemostasis in patients with non-variceal bleeding (NVGIB) with standard therapy has improved outcomes. However, persistent bleeding and re-bleeding continues to drive morbidity and mortality. Use of Over-the-scope clips (OTSC) is an emerging treatment modality for managing gastrointestinal bleeding. We performed a systematic review and meta-analysis to evaluate the ability of OTSC to achieve primary hemostasis and re-bleeding rates as primary therapy and rescue endoscopic interventions in patients with NVGIB...
November 7, 2018: Minerva Gastroenterologica e Dietologica
Alfredo Marzano, Alessandra Tucci, Claudia Chialá, Giorgio M Saracco, Maurizio Fadda, Wilma Debernardi Venon
BACKGROUND: In hepatitis B virus (HBV)-related cirrhosis the antiviral therapy reduces portal hypertension (PH) and risk of hepatocellular carcinoma (HCC). AIM: This study assessed the prognostic role of LSPS score (liver stiffness value X spleen diameter/platelet count) in predicting these goals in cirrhotic patients responsive to antiviral therapy. METHODS: The correlation between LSPS, PH, esophageal varices (EVs) and HCC was evaluated in 121 cirrhotic patients treated with nucleos(t)ide analogues (NUCs)...
October 24, 2018: Minerva Gastroenterologica e Dietologica
Roberto de Sire, Gianenrico Rizzatti, Fabio Ingravalle, Marco Pizzoferrato, Valentina Petito, Loris Lopetuso, Cristina Graziani, Alessandro de Sire, Maria Chiara Mentella, Maria Cristina Mele, Antonio Gasbarrini, Franco Scaldaferri
In recent years, there has been an increasing interest on muscle wasting, considering the reduction of quality of life and the increase of morbidity and mortality associated. Sarcopenia and cachexia represent two conditions of reduction of muscle mass, sharing several elements involved in their pathogenesis, such as systemic inflammation, impaired muscle protein synthesis, increased muscle apoptosis, mitochondrial dysfunction in skeletal muscle tissue and insulin resistance. These features often characterize cancer, inactivity or denervation, but also inflammatory diseases, such as chronic obstructive pulmonary disease, renal failure, cardiac failure, rheumatoid arthritis, inflammatory bowel disease and aging in general...
December 2018: Minerva Gastroenterologica e Dietologica
Pierluigi Toniutto, Davide Bitetto, Ezio Fornasiere, Elisa Fumolo
Liver transplantation (LT) has become the treatment of choice for a wide range of liver diseases in both adult and pediatric patients. Until recently, the largest proportion of LT in adults, were performed in patients with hepatitis C (HCV) related cirrhosis. The recent availability of safe and effective direct antiviral agents to cure HCV infection in almost all patients whatever the HCV genotype and severity of liver disease, will reduce the need for LT in this category of recipients. Thus, it is presumed that in the next 1 to 2 decades HCV related liver disease will diminish substantially, whereas non-alcoholic steato-hepatitis (NASH) will correspondingly escalate as an indication for LT...
October 5, 2018: Minerva Gastroenterologica e Dietologica
Stella I Smith, Tolulope Jolaiya, Charles Onyekwere, Muinah Fowora, Rose Ugiagbe, Ifeanyi Agbo, Cara Cookey, Olufunmilayo Lesi, Dennis Ndububa, Olusegun Adekanle, Pia Palamides, Isaac Adeleye, Henry Njom, Idowu Ayodeji, Anna Clarke, Rinaldo Pellicano
BACKGROUND: This multicenter study was undertaken to determine the prevalence of Helicobacter pylori (H. pylori) infection among dyspeptic patients with and without type 2 diabetes mellitus (T2DM). METHODS: Patients with dyspepsia were recruited from tertiary teaching hospitals, three in the South-West and one in the South-South regions of Nigeria, between November 2016 and August 2017. The participants had breath samples analyzed for H. pylori by the Urea Breath Test (UBT) following manufacturer's instructions...
October 2, 2018: Minerva Gastroenterologica e Dietologica
Walter Elisei, Giovanni Brandimarte, Antonio Tursi
The incidence of diverticulosis and diverticular disease of the colon is increasing worldwide. Although the majority of patients remains asymptomatic long-life, the prevalence of diverticular disease of the colon, including acute diverticulitis, is substantial and is becoming a significant burden on National Health Systems in terms of direct and indirect costs. Fiber, non-absorbable antibiotics and probiotics seem to be effective in treating symptomatic and uncomplicated patients, and 5-aminosalicylic acid might help prevent acute diverticulitis...
October 2, 2018: Minerva Gastroenterologica e Dietologica
Rachel N Pauls, Joshua B Max
BACKGROUND: Little is known regarding the dietary behaviors and epidemiology of irritable bowel syndrome (IBS) patients in the United States (US). METHODS: This was an IRB-approved cross-sectional survey conducted via a secured online server (SurveyMonkey®). A representative sample of the US population were queried regarding demographics, gastrointestinal (GI) symptoms, treatments and dietary practices. Of 1,718 respondents, 161 reported IBS. These were compared to 1,116 subjects reporting no GI diagnosis (controls)...
October 2, 2018: Minerva Gastroenterologica e Dietologica
Adil Mir, Rupinder Mann, Andrew Canakis, Steven Lichtenstein
BACKGROUND: More than 70 million americans (23% of the US population) have non-cardiac chest pain at least once in their lifetime with gastroesophageal reflux disease (GERD) being the leading cause (37-66%). Current guidelines support the use of a proton pump inhibitor (PPI) prior to invasive or noninvasive testing as a diagnostic, therapeutic and cost effective method as a part of High Value Care recommendations. METHODS: We performed a chart review of 126 patients admitted to the hospital under observation status who underwent upper GI endoscopies in the hospital at 3 different urban community hospitals...
October 2, 2018: Minerva Gastroenterologica e Dietologica
Giorgio Lisi, Michela Campanelli, Domenico Mascagni, Simona Grande, Michele Grande, Giovanni Milito
BACKGROUND: Radiofrequency has been introduced as an instrument conceived to upgrade the conventional treatment of hemorrhoidectomy. To reduce the economic aspect, recently has been introduced a new radiofrequency device: VojantTM. Aim was to compare clinical outcomes of hemorrhoidectomy with LigaSureTM and VojantTM, performed with the Milligan- Morgan technique, in medium-term perspective. METHODS: Between January 2016 and December 2016, 50 consecutive patients with symptomatic grade III and IV were scheduled for surgical treatment...
October 2, 2018: Minerva Gastroenterologica e Dietologica
Jürgen Feisthammel, Kien Vu Trung, Marcus Hollenbach, Joachim Mössner, Albrecht Hoffmeister
BACKGROUND: The insufflation of gas during colonoscopy leads to distention of the colon with abdominal discomfort and pain for the patients. Use of CO2 during endoscopy is reported to minimize abdominal discomfort during and after endoscopy. Aim of this study was to find out whether this improvement leads to decreased dosage of sedation drugs in order to improve patient's safety and satisfaction. METHODS: In this double-blind, randomized and controlled study 150 Patients referred to colonoscopy were assigned to either CO2 or air insufflation...
September 2018: Minerva Gastroenterologica e Dietologica
Philippe Lehours
Helicobacter pylori colonizes the stomach of half of humanity. The prevalence of this infection is higher among people of low socioeconomic status and from developing countries. In the absence of effective antibiotic treatment, the infection persists decades or even lifetime. The diagnosis of H. pylori can be made by invasive methods when biopsies are obtained: culture, histological examination, polymerase chain reaction or rapid urease test. Non-invasive methods have been developed, including the urea breath test, a test of high reliability, particularly suitable for post-treatment monitoring, but also the fecal antigen test, as well as the detection of antibodies in the serum...
September 2018: Minerva Gastroenterologica e Dietologica
Rinaldo Pellicano, Rocco M Zagari, Songhua Zhang, Giorgio M Saracco, Steven F Moss
Over the past 30 years, multidrug regimens consisting of a proton pump inhibitor (PPI) and two or three antibiotics have been used in treating Helicobacter pylori (H. pylori) infection. In clinical practice, the optimal regimen to cure H. pylori infection should be decided regionally. Considering the first treatment, the Maastricht V/Florence Consensus Report and the American College of Gastroenterology Clinical Management Guideline highlight that in countries with low clarithromycin resistance rates (<15%), an empiric clarithromycin-based regimen can be used...
September 2018: Minerva Gastroenterologica e Dietologica
Gianenrico Rizzatti, Maria V Matteo, Gianluca Ianiro, Giovanni Cammarota, Francesco Franceschi, Antonio Gasbarrini
Helicobacter pylori is one of the most common gastrointestinal infection affecting humans worldwide. Hp colonizes the stomach with preferential trophism for the antrum. Hp infection is associated with the development of a chronic gastritis and subsequently with several gastric diseases such as peptic disease, gastric carcinoma and MALT lymphoma. Moreover, Helicobacter pylori infection has also been reported in literature to be associated with many other extra-gastric conditions including sideropenic anemia, thrombocytopenia, neurological, liver and cardiovascular diseases...
September 2018: Minerva Gastroenterologica e Dietologica
Gianni Testino, Silvia Leone, Sharmila Fagoonee, Rinaldo Pellicano
No abstract text is available yet for this article.
September 2018: Minerva Gastroenterologica e Dietologica
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