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Minerva Gastroenterologica e Dietologica

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https://www.readbyqxmd.com/read/29652111/actual-diagnosis-of-helicobacter-pylori-infection
#1
Philippe Lehours
Helicobacter pylori colonizes the stomach of half of humanity. The prevalence of this infection is higher among people of low socioeconomic status and from developing countries. In the absence of effective antibiotic treatment, the infection persists decades or even lifetime. The diagnosis of H. pylori can be made by invasive methods when biopsies are obtained: culture, histological examination, polymerase chain reaction or rapid urease test. Non-invasive methods have been developed, including the urea breath test, a test of high reliability, particularly suitable for post treatment monitoring, but also the fecal antigen test, as well as the detection of antibodies in the serum...
April 12, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29600698/role-of-microbiota-in-the-autism-spectrum-disorders
#2
Daniela Campion, Paola Ponzo, Carlo Alessandria, Giorgio M Saracco, Federico Balzola
Autism Spectrum Disorder (ASD) defines a set of neurodevelopmental disorders characterized by persistent deficits in social communication and interaction, along with repetitive patterns of behavior. Symptoms generally appear in the early developmental period and cause significant impairment in individual and social functioning. In recent years the increased prevalence of ASD, along with the evidence of a significant link between autism and gastrointestinal (GI) disturbances, raised a special interest in exploringì the reciprocal influences between gut and brain...
March 30, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29600697/pharmacological-considerations-and-step-by-step-proposal-for-the-treatment-of-helicobacter-pylori-infection-in-the-year-2018
#3
Rinaldo Pellicano, Rocco M Zagari, Songhua Zhang, Giorgio M Saracco, Steven F Moss
Over the past 30 years, multidrug regimens consisting of a proton pump inhibitor (PPI) and two or three antibiotics have been used in treating Helicobacter pylori (H. pylori) infection. In clinical practice, the optimal regimen to cure H. pylori infection should be decided regionally. Considering the first treatment, the Maastricht V/Florence Consensus Report and the American College of Gastroenterology Clinical Management Guideline highlight that in countries with low clarithromycin resistance rates (<15%), an empiric clarithromycin-based regimen can be used...
March 30, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29600696/helicobacter-pylori-in-metabolic-related-diseases
#4
Gianenrico Rizzatti, Maria V Matteo, Gianluca Ianiro, Giovanni Cammarota, Francesco Franceschi, Antonio Gasbarrini
Helicobacter pylori is one of the most common gastrointestinal infection affecting humans worldwide. Hp colonizes the stomach with preferential trophism for the antrum. Hp infection is associated with the development of a chronic gastritis and subsequently with several gastric diseases such as peptic disease, gastric carcinoma and MALT lymphoma. Moreover, Helicobacter pylori infection has also been reported in literature to be associated with many other extra-gastric conditions including sideropenic anemia, thrombocytopenia, neurological, liver and cardiovascular diseases...
March 30, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29553226/a-rare-case-of-gastric-fistulization-of-a-main-duct-ipmn-a-case-report
#5
Pablo Cortegoso Valdivia, Mauro Bruno, Silvia Gaia, Giorgio M Saracco, Claudio DE Angelis
We report a rare case of gastric fistulization in a patient with main-duct (MD) intraductal papillary mucinous neoplasm (IPMN). Fistulization to adjacent organs is a rare complication of this disease, mainly affecting the duodenum; the fact that the stomach was the only organ involved makes this case even more peculiar. The diagnosis of the fistula was made after examination with Endoscopic Ultrasound (EUS), since a previous computed tomography (CT) scan wasn't able to detect it.
March 16, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29521488/the-role-of-adenosyl-methionine-in-alcoholic-liver-disease-and-intrahepatic-cholestasis
#6
Gianni Testino, Silvia Leone, Sharmila Fagoonee, Rinaldo Pellicano
No abstract text is available yet for this article.
March 8, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29631387/liver-transplantation-indications-and-outcomes
#7
Patrizia Burra, Giacomo Germani
No abstract text is available yet for this article.
June 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29307150/comment-on-helicobacter-pylori-eradication-using-metronidazole
#8
Ramy Younes, Anna Morgando
No abstract text is available yet for this article.
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29307149/capsule-endoscopic-appearance-of-a-meckel-s-diverticulum-in-an-adult
#9
Thanh-Truc LE, Mohammad Bilal, Eric W Gou, Sreeram Parupudi
No abstract text is available yet for this article.
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29307148/panparietal-cholesterolosis-xantho-granulomatous-cholecystitis-precursor
#10
Adriana Handra-Luca
No abstract text is available yet for this article.
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29307147/internist-anesthesiologist-and-surgeon-use-of-ketogenic-diet
#11
Lorenzo Cenci, Antonio Paoli, Hesham R Omar, Prachiti Dalvi, Enrico M Camporesi, Devanand Mangar, Silvia Quartesan, Alberto Fiorito, Gerardo Bosco
Ketogenic diet is being increasingly utilized in recent decades because of its success as an effective tool for short and intermediate-term weight loss. Promoting physiological ketosis from a drastically low carbohydrate diet is the fundamental basis for this diet regime. Though debated, these diets have been demonstrated to be effective, at least in the short- to medium terms, to manage excess weight, hyperlipidemia, and other cardiovascular risk factors. We reviewed the cardiovascular, metabolic, anesthetic, and postsurgical profiles in the literature and summarized technical issues of anesthesia and surgery along with long-term changes from published papers...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29307146/prevalent-use-of-combined-prophylaxis-of-hepatitis-b-after-liver-transplantation-in-italy-results-of-a-national-survey-in-a-large-cohort
#12
Alfredo Marzano, Pietro Andreone, Patrizia Boccagni, Patrizia Burra, Francesco Caneschi, Pasquale F Conoscitore, Carmine Coppola, Luciano DE Carlis, Stefano Fagiuoli, Paolo Forte, Giovanni B Gaeta, Rosa M Iemmolo, Anna Lotti Suffredini, Michele Mazzola, Manuela Merli, Gianpaolo Parrilli, Guido Piai, Maria R Piras, Mauro Salizzoni, Mariarosa Tamè, Giuseppe Tisone, Pierluigi Toniutto, Giovanni Vennarecci, Riccardo Volpes, Fausto Zamboni, Lucio Caccamo
BACKGROUND: Prophylaxis of hepatitis B after liver transplantation with antiviral(s) and immunoglobulins efficiently protect the majority of recipients; however recent experiences suggest a decline of HBsAg-positive candidates and the use of hepatitis B Immunoglobulin-free schedules. METHODS: This national survey evaluated the epidemiology and clinical results of hepatitis B prophylaxis among 10,365 liver transplants performed in 25 years in 13 Italian centers. RESULTS: With a percentage of 22, 2260 procedures were performed in HBsAg-positive recipients and 714 out of 1080 anti-HBc-positive grafts were used in HBsAg-negative recipients; a total of 2974 patients (29%) were considered at risk of hepatitis B after liver transplantation...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28948754/histopathology-grading-and-staging-of-nonalcoholic-fatty-liver-disease
#13
David E Kleiner
Nonalcoholic fatty liver disease (NAFLD) is the liver disease associated with obesity, diabetes and the metabolic syndrome. Although steatosis is a key histological feature, liver biopsies of patients with NAFLD can show a wide range of other findings, including portal and lobular inflammation, ballooning and apoptotic hepatocellular injury, Mallory-Denk bodies, megamitochondria and fibrosis. Nonalcoholic steatohepatitis (NASH) is a progressive subtype of NAFLD first defined by analogy to alcoholic hepatitis...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28895372/-tipping-extracellular-matrix-remodeling-towards-regression-of-liver-fibrosis-novel-concepts
#14
Fernando Magdaleno, Robert Schierwagen, Frank E Uschner, Jonel Trebicka
Fibrosis development was initially conceived as an incessant progressive condition. Nowadays, it has become evident that fibrotic tissue undergoes a continuous two-way process: fibrogenesis and fibrinolysis, characterizing the remodeling of extracellular matrix (ECM). However, in established fibrosis, this two-way process is tipped towards fibrogenesis and this leads to a self-perpetuating accumulation of ECM, a distinct metabolic unit, together with other cells and processes promoting fibrosis deposition. Several mechanisms promote fibrosis regression, such as degradation of ECM, infiltration of restorative macrophages, prevention of the epithelial-mesenchymal transition of hepatocytes, restoration of the liver sinusoidal endothelial cells' differentiation phenotype, and reversion to quiescence, apoptosis and senescence of hepatic stellate cells (HSC)...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28895371/performance-of-the-over-the-scope-clip-system-in-the-endoscopic-closure-of-iatrogenic-gastrointestinal-perforations-and-post-surgical-leaks-and-fistulas
#15
Giuseppe Iabichino, Leonardo H Eusebi, Maria A Palamara, Monica Arena, Rinaldo Pellicano, Pierluigi Consolo, Sharmila Fagoonee, Loretta Amato, Enrico Opocher, Matteo Barabino, Carmelo Luigiano
The increased invasiveness of endoscopic procedures and complex surgical interventions has resulted in an increased number of gastrointestinal iatrogenic defects, such as perforations, leak and fistulas. The conventional treatment for these gastrointestinal defects is surgery, with considerable risks especially in emergency situations and in patients with comorbidities. The Ovesco over-the-scope clip (OTSC) system (Ovesco Endoscopy AG, Tübingen, Germany) and more recently, the Padlock Clip™ (Aponos Medical, Kingston, NH, USA) have shown promising results in the treatment of gastrointestinal defects...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28895370/eosinophilic-esophagitis-current-evidence-based-diagnosis-and-treatment-in-children-and-adults
#16
Alfredo J Lucendo
Eosinophilic esophagitis (EoE) is a disease caused by an immune response to food antigens in contact with the esophageal mucosa that has arisen as a common disorder in current clinical practice. Its diagnosis is defined by the combination of symptoms of esophageal dysfunction and inflammation of the esophageal mucosa predominantly by eosinophils. Its chronic course and frequent progression to subepithelial fibrosis leading to strictures and narrow esophagus indicate the need for treatment. Information provided by recent clinical trials and systematic reviews allowed for the development of new clinical guidelines, endorsed by several European scientific societies...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28875689/liver-fibrosis-in-the-context-of-nonalcoholic-steatohepatitis-the-role-of-adipokines
#17
Giovanni DI Maira, Mirella Pastore, Fabio Marra
Liver fibrosis is a multifaceted process that occurs as a consequence of chronic liver injury. This process is characterized by inflammation, activation of matrix-producing cells, matrix deposition and remodeling, and epithelial cell regeneration. In subjects with chronic liver damage, fibrogenesis is favored by the presence of obesity and insulin resistance, which are also relevant risk factors for the development and progression of nonalcoholic steatohepatitis (NASH). It is now well-known that adipose tissue is not only involved in energy storage but also functions as an endocrine organ that secretes various bioactive substances known as adipokines...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28875688/clinical-utility-of-the-patency-capsule-a-large-volume-center-experience
#18
Armando Peixoto, Marco Silva, Rosa Coelho, Rui Gaspar, Rodrigo Liberal, Rui Castro, Andreia Albuquerque, Margarida Marques, Hélder Cardoso, Guilherme Macedo
BACKGROUND: In patients with suspected or known obstructive gastrointestinal pathology, the use of patency capsule (PC) aims to minimize the risk of subsequent retention of the endoscopic capsule. However, its clinical utility is not consensual. The aim was to evaluate the indications, results and safety profile of the PC. METHODS: Retrospective analysis of PCs (agile patency capsule) conducted between 2011 and 2015. Patency evaluation was performed after 30 hours, with radiological confirmation if PC was detected...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28398025/hepatocarcinoma-genetic-and-epigenetic-features
#19
Angela Lombardi, Anna Grimaldi, Silvia Zappavigna, Gabriella Misso, Michele Caraglia
HCC is the third leading cause of cancer-related deaths worldwide, accounting for about 1 million deaths annually. The incidence of HCC is highest in Asia and Africa, where the endemic high prevalence of hepatitis B and hepatitis C strongly predisposes to the development of chronic liver disease and subsequent development of HCC. Patients with HCC generally present at an advanced stage due to compensated cirrhosis defined by the absence of pathognomonic symptoms, resulting in death within 6 to 20 months, suggesting an urgent need in treatment modalities that will dramatically decrease the mortality rate of HCC...
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29458241/management-of-helicobacter-pylori-in-piedmont-italy
#20
Davide G Ribaldone, Dario Mazzucco, Sharmila Fagoonee, Lucia Crocellà, Alessandro Lavagna, Mario Fracchia, Gian P Caviglia, Daniele Simondi, Rodolfo Rocca, Marco Astegiano
Helicobacter pylori (H. pylori) is a Gram-negative bacterium, usually acquired during childhood, whose natural habitat is the gastric lumen. H. pylori is accepted as the most important cause of gastritis and peptic ulcer in humans. Nevertheless, its important role in the pathogenesis of gastric cancer as well as in several extra-gastroduodenal diseases has been confirmed. The aim of this work is to discuss, for the first time in a single article, all publications concerning H. pylori infection arising from Piedmont region, Italy, where in 1893 Giulio Bizzozero was the first who observed and described spiral organisms in the stomach of animal models...
February 19, 2018: Minerva Gastroenterologica e Dietologica
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