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Ultrasound in Obstetrics & Gynecology

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https://www.readbyqxmd.com/read/29750436/fetal-blood-gas-values-during-fetoscopic-myelomeningocele-repair-performed-under-carbon-dioxide-insufflation
#1
Ahmet A Baschat, Edward S Ahn, Jamie Murphy, Jena L Miller
BACKGROUND: Fetoscopic myelomeningocele (MMC) repair is performed with intrauterine carbon dioxide (CO2 ) insufflation. While lamb experiments have shown significant fetal acidemia following CO2 insufflation corresponding information for human pregnancies is not available. CASES: We performed umbilical venous cord blood sampling in three patients during fetoscopic MMC repair at 25+1, 25+3 and 24+1 weeks gestation. Fetal venous pH at the beginning of CO2 insufflation were 7...
May 10, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29749657/fundal-pressure-in-second-stage-of-labor-kristeller-maneuver-is-associated-with-higher-risk-of-levator-ani-muscle-avulsion
#2
Aly Youssef, Ginevra Salsi, Ilaria Cataneo, Giuseppina Pacella, Carlotta Azzarone, Maria Chiara Paganotto, Jovana Krsmanovic, Elisa Montaguti, Luisa Cariello, Federica Bellussi, Nicola Rizzo, Gianluigi Pilu
OBJECTIVE: to investigate the association between fundal pressure in the second stage (Kristeller maneuver) and the risk of levator ani muscle (LAM) injury. METHODS: This was a prospective case-control study conducted in our university hospital. We recruited women immediately following their first vaginal delivery. Women who underwent Kristeller maneuver were recruited as cases. For each case, a control (no Kristeller) was recruited matched by BMI, epidural analgesia, second stage duration and birthweight...
May 10, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29749110/metformin-for-the-prevention-of-hypertensive-disorders-of-pregnancy-in-women-with-gestational-diabetes-and-obesity-a-systematic-review-and-meta-analysis
#3
REVIEW
Erkan Kalafat, Yavuz Emre Sukur, Abdulkadir, Basky Thilaganathan, Asma Khalil
OBJECTIVES: Metformin has been reported to reduce the risk of preeclampsia. It is also known to influence soluble fms-like tyrosine kinase-1 (sFlt-1) levels, which correlate significantly with the gestation of onset and severity of preeclampsia. The main aim of this systematic review and meta-analysis was to determine whether metformin use is associated with the incidence of hypertensive disorders of pregnancy (HDP). METHODS: MEDLINE (1947 - September 2017), Scopus (1970 - September 2017) and the Cochrane Library (since inception - September 2017) were searched for relevant citations in English language...
May 10, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29749081/the-honeycomb-appearance-of-fetal-myofibromatosis
#4
LETTER
M Pekar-Zlotin, O Levinsohn-Tavor, A Livneh, O Sher, Y Melcer, R Maymon
Infantile myofibromatosis (IM) is a benign neoplasm of infancy with an incidence of 1:150,000, presenting in 90% of the cases before two years of age and is rarely encountered in newborns. The mortality rate is 15%, most being with generalized visceral multicentric disease1-4 . Prenatal diagnosis may lead to termination of pregnancy being an option for the parents and the communities who accept such a choice. This article is protected by copyright. All rights reserved.
May 10, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29704280/prediction-of-adverse-pregnancy-outcome-in-monochorionic-diamniotic-twin-pregnancies-complicated-by-selective-fetal-growth-restriction
#5
Caitriona Monaghan, Erkan Kalafat, Julia Binder, Baskaran Thilaganathan, Asma Khalil
OBJECTIVE: To identify key factors implicated in adverse perinatal outcome in monochorionic twin pregnancies complicated by selective fetal growth restriction. METHODS: This is a retrospective cohort study conducted in a single tertiary referral centre included all monochorionic diamniotic (MCDA) twin pregnancies complicated by selective fetal growth restriction (sFGR). The presence of co-existing twin to twin transfusion syndrome (TTTS) was noted. Fetal biometry and Doppler indices, including the umbilical artery (UA) and ductus venosus (DV), were recorded at the time of diagnosis...
April 28, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29704277/prediction-and-prevention-of-small-for-gestational-age-neonates-evidence-from-spree-and-aspre
#6
Min Yi Tan, Liona C Poon, Daniel L Rolnik, Argyro Syngelaki, Catalina de Paco Matallana, Ranjit Akolekar, Simona Cicero, Deepa Janga, Mandeep Singh, Francisca S Molina, Nicola Persico, Jacques C Jani, Walter Plasencia, Elena Greco, George Papaioannou, David Wright, Kypros H Nicolaides
OBJECTIVE: To examine the effect of first trimester screening for preeclampsia (PE) on the prediction of small for gestational age (SGA) neonates and the effect of prophylactic use of aspirin on the prevention of SGA. METHODS: The data for this study were derived from two multicentre studies. In SPREE we investigated the performance of screening for PE by a combination of maternal characteristics and biomarkers at 11-13 weeks' gestation. In ASPRE women with singleton pregnancies identified by combined screening as being at high risk for preterm-PE (>1 in 100) participated in a trial of aspirin (150 mg/day from 11 to 14 until 36 weeks' gestation), compared to placebo...
April 28, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29700879/morphometry-of-the-nulliparous-pelvic-floor
#7
E M Nesbitt-Hawes, H P Dietz, J A Abbott
OBJECTIVES: The objective of this study was to describe morphometry of the pelvic floor for a large population of nulliparous women. METHODS: A prospective study was performed between January 2013-November 2015, recruiting women attending a general gynaecology clinic. Following collection of demographic data, translabial four-dimensional ultrasound (4DUS) was performed. Dynamic volumes of pelvic floor muscle contraction and Valsalva were recorded and analysed at a later date by an assessor blinded to demographic details...
April 27, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29700877/use-of-new-intrauterine-shunt-for-fetal-fluid-accumulations-single-center-experience-from-first-17-cases
#8
LETTER
L N Nørgaard, K Søgaard, L N Jensen, C Ekelund, B H Kahrs, A Tabor, K Sundberg
Pleural effusion is the most common fluid-accumulation in the fetus with a prevalence of 1:15.000-24.000 pregnancies.1 The clinical picture is highly variable ranging from spontaneous resolution to lung hypoplasia, hydrops and death.1 Treatment options include thoracocentesis, thoraco-amniotic shunting and pleurodesis using OK-432.2 The conventional thoraco-amniotic shunts are applied using a 13-16G trochar.3,4 Somatex® Intrauterine Shunt (IUS) was launched in 2014 and consists of a self-expanding nitinol wire mesh with an inner silicone coating to be inserted through an 18G/1...
April 27, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29700870/the-cost-effectiveness-of-first-trimester-screening-and-early-preventative-use-of-aspirin-in-women-at-high-risk-of-early-onset-pre-eclampsia
#9
Dayne Ortved, T Lee-Ann Hawkins, Jo-Ann Johnson, Jon Hyett, Amy Metcalfe
OBJECTIVE: Pre-eclampsia (PE) remains a leading cause of maternal and fetal morbidity and mortality. A first trimester screening algorithm predicting the risk of early onset PE has been developed and validated. Early prediction coupled with initiation of aspirin at 11 to 13 weeks in women identified as high risk is effective at reducing the prevalence of early onset PE. The aim of this study is to evaluate the cost-effectiveness of this first trimester screening program coupled with early use of low-dose aspirin in women at high risk of developing early onset PE versus current practice...
April 27, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29696704/fetal-medicine-foundation-fetal-and-neonatal-population-weight-charts
#10
K H Nicolaides, D Wright, A Syngelaki, A Wright, R Akolekar
OBJECTIVE: To develop fetal and neonatal population weight charts. The rationale for this objective is that while reference ranges of estimated fetal weight (EFW) are representative of the whole population, the traditional approach of deriving birth-weight (BW) charts is misleading because a high proportion of babies born preterm arises from pathological pregnancies. We propose that the reference population for BW charts, as in the case of EFW charts, should be all babies at a given gestational age including those still in utero...
April 26, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29667240/use-of-simulators-for-the-assessment-of-trainees-competence-trendy-toys-or-valuable-instruments
#11
EDITORIAL
Martin G Tolsgaard, Gihad E Chalouhi
Over the past decade, ultrasound simulators have been increasingly used as an adjunct to clinical training in Obstetrics and Gynaecology. Studies have shown that providing initial simulation-based ultrasound training leads to sustained improvements in clinical performances1 including improved diagnostic accuracy,2 reduced need for supervised practice, and decreased patient discomfort.3 .
April 17, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29660186/influence-of-prenatal-diagnosis-of-abnormally-invasive-placenta-on-maternal-outcome-a-systematic-review-and-meta-analysis
#12
REVIEW
Danilo Buca, Marco Liberati, Giuseppe Calì, Francesco Forlani, Claudia Caisutti, Maria Elena Flacco, Lamberto Manzoli, Alessandra Familiari, Giovanni Scambia, Francesco D'Antonio
OBJECTIVES: The aim of this systematic review was to ascertain the impact of prenatal diagnosis on surgical outcome of women affected by AIP. METHODS: Medline, Embase, CINAHL and Cochrane databases were searched. The outcomes observed were: gestational age at birth (weeks), amount of blood loss (l), units of red blood cells (RBC), platelets (PLT) and fresh frozen plasma (FFP) transfused, length of stay in hospital and in intensive care unit (days), urinary tract injuries and infection...
April 16, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29660172/predictive-accuracy-of-the-southwest-thames-obstetric-research-collaborative-stork-chorionicity-specific-twin-growth-charts-for-stillbirth-a-validation-study
#13
Erkan Kalafat, Mercedes Sebghati, Basky Thilaganathan, Asma Khalil
OBJECTIVE: Twin pregnancy is associated with 2-3 fold increased risk of stillbirth compared to singletons. Despite the fact that the growth pattern has been shown to differ in twins compared to singletons, it is controversial whether twin-specific growth charts should be routinely used. A major goal of prenatal ultrasound is to identify fetuses suffering from growth restriction at risk of stillbirth. The main aim of this study was to compare the performance of chorionicity-specific twin charts with singleton charts, both customized and non-customized, in the antenatal prediction of small-for-gestational age (SGA) stillborn and liveborn fetuses...
April 16, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29611251/ultrasonographic-estimation-of-fetal-weight-development-of-new-model-and-assessment-of-performance-of-previous-models
#14
Aymen Hammami, Alicia Mazer Zumaeta, Argyro Syngelaki, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVE: To develop a new formula for ultrasonographic estimation of fetal weight (EFW) and evaluate the accuracy of this and all previous formulas in the prediction of birthweight. METHODS: The study population consisted of 5,163 singleton pregnancies with fetal biometry at 22-43 weeks' gestation and livebirth of phenotypically normal neonates within 2 days of the ultrasound examination. Multivariable fractional polynomial analysis was used to determine the combination of variables that provided the best-fitting models for EFW...
April 2, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29607569/neurodevelopmental-outcome-of-fetal-isolated-ventricular-asymmetry-without-dilation-a-cohort-study
#15
Raanan Meyer, Omer Bar-Yosef, Eran Barzilay, Dana Hoffman, Shlomi Toussia-Cohen, Elad Zvi, Reuven Achiron, Eldad Katorza
OBJECTIVE: Fetal isolated ventricular asymmetry (IVA) is a relatively common finding in pregnancy, but data regarding its effect on neurodevelopmental outcome is scarce and principally founded on ultrasound-based studies. The purpose of this study was to assess the outcome of such cases in a magnetic resonance imaging based study. METHODS: Cases referred to fetal brain MR imaging as part of the investigation of IVA without ventriculomegaly (≤10 mm), identified during routine ultrasound examinations, were assessed for possible inclusion...
April 1, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29607558/outcome-reporting-across-randomised-trials-and-observational-studies-evaluating-treatments-for-twin-twin-transfusion-syndrome-a-systematic-review
#16
REVIEW
Helen Perry, James M N Duffy, Ogochukwu Umadia, Asma Khalil
BACKGROUND: Twin-Twin Transfusion syndrome is associated with significant mortality and morbidity. Potential treatments require robust evaluation. The aim of this study was to evaluate outcome reporting across observational studies and randomised controlled trials assessing treatments for twin-twin transfusion syndrome (TTTS). METHODS: Cochrane Central Register of Controlled Trials, EMBASE and Medline were searched from inception to August 2016. Observational studies and randomised controlled trials reporting outcomes following a treatment for TTTS in monochorionic-diamniotic twin pregnancies and monochorionic-triamniotic or dichorionic-triamniotic triplet pregnancies were included...
April 1, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29607557/maternal-hemodynamics-fetal-biometry-and-dopplers-in-pregnancies-followed-up-for-suspected-fetal-growth-restriction
#17
Llinos A Roberts, Hua Zen Ling, Liona Poon, Kypros H Nicolaides, Nikos A Kametas
OBJECTIVES: To assess whether in a cohort of patients with small for gestational age (SGA) foetuses with estimated fetal weight ≤10th percentile, maternal hemodynamics, fetal biometry and Dopplers at presentation, can predict the subsequent development of abnormal fetal Dopplers or delivery with birthweight <3rd percentile. METHODS: The study population comprised of 86 singleton pregnancies with SGA fetuses presenting at a median gestational age of 32 (range 26-35) weeks...
April 1, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29577503/comparison-between-potassium-chloride-and-lidocaine-as-lethal-agents-for-feticide-for-the-termination-of-pregnancy
#18
LETTER
Romy Rayssiguier, Yuri Musizzano, Marie-Josée Perez, Eve Mousty, Audrey Ménard, Pierre Boulot, Coralie Dumont, Florent Fuchs
In France, the practice of termination of pregnancy (TOP) can be performed regardless of gestational age in specific circumstances (a fetus that is highly likely to be affected by severe and uncorrectable condition or where the mother health is in danger and with medical approval).
March 25, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29577499/venous-and-autonomic-function-in-formerly-pre-eclamptic-women-and-bmi-matched-controls
#19
Wieteke M Heidema, Joris van Drongelen, Marc E A Spaanderman, Ralph R Scholten
INTRODUCTION: Pre-pregnancy reduced plasma volume increases the risk on subsequent pre-eclamptic pregnancy. Reduced plasma volume is thought to reflect venous reserve capacity, especially when venous vasculature is constricted and sympathetic tone is elevated. As obesity might affect these variables and also relates to pre-eclampsia, increased body weight may underlie these observations. We hypothesized that the relationship between reduced venous reserve and preeclampsia is independent of body mass index (BMI)...
March 25, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29575304/performance-of-commercially-available-placental-growth-factor-tests-in-women-with-suspected-preterm-pre-eclampsia-the-compare-study
#20
F P McCarthy, C Gill, P T Seed, K Bramham, L C Chappell, A H Shennan
OBJECTIVE: To compare the performance of three PlGF-based kits in prediction of time to delivery within 14 days in women with suspected preterm pre-eclampsia prior to 35 weeks' gestation. METHODS: We conducted a retrospective analysis of samples collected from three prospective pregnancy cohort studies. Participants were pregnant women with suspected preterm pre-eclampsia recruited in tertiary maternity units in the UK and Ireland. Samples were analysed simultaneously according to manufacturer's directions...
March 25, 2018: Ultrasound in Obstetrics & Gynecology
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