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Ultrasound in Obstetrics & Gynecology

F Moro, T Pasciuto, D Djokovic, A Di Legge, V Granato, M C Moruzzi, R Mancari, G F Annoni, D Fischerova, D Franchi, G Scambia, A C Testa
OBJECTIVES: To investigate ultrasound features and the best cut-off value of CA125/CEA ratio to discriminate benign and primary malignant ovarian neoplasms from ovarian metastases in selected groups of morphological ovarian masses: multilocular masses with 5 or more locules and multilocular-solid masses. METHODS: Patients with multilocular (≥5 locules) or multilocular-solid ovarian masses, operated on within three months from ultrasound, and tumor markers (CEA and CA125) available at diagnosis were retrospectively identified from three ultrasound centers...
July 5, 2018: Ultrasound in Obstetrics & Gynecology
Ignacio Alonso, Guillermo Azumendi, María Romero, José Ramón Anderica, José Ramón Herrero, Pedro Azumendi, Marisa Borenstein
The optic chiasm (OC) is an X-shaped structure formed by the crossing of the optic nerves in an axial view of the fetal brain. It is located in the chiasmatic cistern and it is surrounded by the Willis circle. The anterior cerebral arteries lay anteriorly, the posterior communicant arteries lay laterally and the posterior cerebral arteries are identified posteriorly. The decussation or centre of the OC corresponds to the origin of the middle cerebral arteries laterally arising from internal carotids. This article is protected by copyright...
July 5, 2018: Ultrasound in Obstetrics & Gynecology
F Pozzati, F Moro, T Pasciuto, C Gallo, F Ciccarone, D Franchi, R Mancari, S Giunchi, D Timmerman, C Landolfo, E Epstein, V Chiappa, D Fischerova, R Fruscio, G F Zannoni, L Valentin, G Scambia, A C Testa
OBJECTIVE: To describe clinical and ultrasound characteristics of ovarian pure clear cell carcinoma. METHODS: This is a retrospective study performed in 11 ultrasound centers. From the International Ovarian Tumor Analysis (IOTA) database we identified 105 patients with a histologically confirmed pure clear cell carcinoma of the ovary who had undergone preoperative ultrasound examination by an experienced ultrasound examiner between 1999 and 2016. An additional 47 patients diagnosed with pure clear cell carcinoma between 1999 and 2016 and with available complete pre-operative ultrasound reports were retrospectively identified from the databases of the departments of gynecological oncology in the participating centers...
July 5, 2018: Ultrasound in Obstetrics & Gynecology
F Fontanella, P N Adama van Scheltema, L Duin, T E Cohen-Overbeek, E Pajkrt, M N Bekker, C Willekes, D Oepkes, C M Bilardo
AIM: to propose a staging system for congenital Lower Urinary Tract Obstructions (LUTO) capable of predicting the severity of the condition and its prognosis. METHODS: This was a national retrospective study carried out at the eight Academic Hospitals in the Netherlands. We collected prenatal and postnatal data of fetuses at high-risk of isolated LUTO and managed conservatively. Postnatal renal function was assessed by the estimated glomerular filtration rate (eGFR), calculated with the Schwartz formula, considering the length of the infant and the creatinine nadir in the first year of age...
July 5, 2018: Ultrasound in Obstetrics & Gynecology
Rasha Kamel, Aly Youssef
OBJECTIVES: To assess the reliability of fetal occiput and spine position determination in nulliparous women prior to the induction of labor (IOL). We aimed also to evaluate the value of identifying the fetal occiput and spine positions prior to IOL in the prediction of labor outcome. METHODS: A series of 136 nulliparous were recruited immediately after the decision of induction of labor. Transabdominal ultrasound was performed to determine fetal head and spine position...
June 26, 2018: Ultrasound in Obstetrics & Gynecology
Karl Oliver Kagan, Martin Enders, Matthias Stefan Schampera, Elisabeth Baeumel, Markus Hoopmann, Annegret Geipel, Christoph Berg, Rangmar Goelz, Luc De Catte, Diethelm Wallwiener, Sara Brucker, Stuart P Adler, Gerhard Jahn, Klaus Hamprecht
OBJECTIVE: To examine the efficacy of biweekly hyperimmunoglobulin (HIG) administration to women with first trimester CMV infection for preventing maternal-fetal transmission of CMV. METHODS: Subjects were 40 pregnant women with a primary CMV infection with a median gestational age at diagnosis of 9.6 weeks with a range of 5.1 to 14.3 weeks' gestation. On average, HIG administration started at 11.1 weeks and continued until 16.6 weeks' gestation. Within this interval, HIG was administered between 2 and 6 times...
June 26, 2018: Ultrasound in Obstetrics & Gynecology
Lieming Wen, Ka Lai Shek, Hans Peter Dietz
OBJECTIVES: To evaluate changes in urethral mobility and configuration after prolapse repair. METHODS: This is a retrospective study on 92 patients before and after surgery for pelvic organ prolapse (POP) without incontinence surgery between 2005 and 2016. All were assessed with an interview, POP-Q and translabial 4D ultrasound. Urethral mobility was evaluated using the urethral motion profile (UMP) where x and y coordinates of 6 equidistant points along the length of urethra were determined both at rest and on Valsalva, relative to the posteroinferior margin of the pubis...
June 26, 2018: Ultrasound in Obstetrics & Gynecology
Floriana Mascilini, Francesca Moro, Rossella De Leo, Giovanni Scambia, Anna Fagotti, Antonia Carla Testa
A 45-year woman, carrying an IUD for 2 years, was referred to our emergency unit for pelvic pain and bleeding. At vaginal examination, the strings of the IUD were not identified. Laboratory parameters were unremarkable. The abdominal radiography documented the presence of IUD in the abdominal cavity (FIG.1). During laparoscopy, the surgeon was unable to localize the IUD and an intraoperative ultrasound examination was requested. Using a sterile transabdominal probe the presence of a tubular hyperechoic structure in the abdominal cavity was confirmed and a precise localization within the bowel loops was defined (FIG 2 and Video 1)...
June 26, 2018: Ultrasound in Obstetrics & Gynecology
M K Van de Waarsenburg, C H van der Vaart, M I J Withagen
No abstract text is available yet for this article.
June 26, 2018: Ultrasound in Obstetrics & Gynecology
Hagit Daum, Vardiella Meiner, Orly Elpeleg, Tamar Harel
OBJECTIVE: To explore the indications and diagnostic outcomes of fetal exomes in a single referral center. METHODS: 77 unrelated fetal samples underwent exome sequencing between 2012-2017. Indications, turnaround time, diagnostic rates, and pregnancy outcomes were investigated. RESULTS: The most common indication for fetal exome sequencing was multiple malformations (21/77, 27%), followed by isolated brain malformations (15/77, 19%). Twelve fetuses (15%) were referred for isolated increased nuchal translucency (IINT)...
June 26, 2018: Ultrasound in Obstetrics & Gynecology
Sarah A Chen, Chin Siang Ong, Narutoshi Hibino, Ahmet A Baschat, Juan R Garcia, Jena L Miller
Conventional 2D ultrasonography is the gold standard for diagnosing congenital heart disease (CHD). Characterization of complex CHD may be limited by 2D imaging methods that lack crucial spatial information as these images are generated as individual "slices" without orientation and with a limited field of view lacking depth, and therefore not ideal for 3D modeling and printing. While approximately 90% of 3D printed models of the cardiovascular system are derived from CT or MRI1 , these modalities are used sparingly in clinical practice...
June 26, 2018: Ultrasound in Obstetrics & Gynecology
M Litwinska, A Syngelaki, A Wright, D Wright, K H Nicolaides
OBJECTIVE: To estimate the patient-specific risk of pre-eclampsia (PE) at 19-24 weeks' gestation by maternal factors and combinations of mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI), serum placental growth factor (PlGF) and serum soluble fms-like tyrosine kinase-1 (sFlt-1). On the basis of the risk of PE, the women would be stratified into high-, intermediate- and low-risk management groups. The high-risk group would require close monitoring for high blood pressure and proteinuria at 24-31 weeks...
June 25, 2018: Ultrasound in Obstetrics & Gynecology
Juan Carlos Melchor, Asma Khalil, Deborah Wing, Ekkehard Schleussner, Daniel Surbek
OBJECTIVE: To assess the diagnostic accuracy of placental alpha- microglobulin-1 (PAMG-1), fetal fibronectin (fFN), and phosphorylated insulin-like growth factor-binding protein-1 (phIGFBP-1) tests in the prediction of spontaneous preterm birth in women with symptoms of preterm labor within 7 days (sPTB≤7d) of testing using formal methods for systematic review. Further analysis looking into performance in low, intermediate and high-risk patient groups. METHODS: Two reviewers independently searched the Cochrane, MEDLINE, PubMed and ResearchGate bibliographic databases...
June 19, 2018: Ultrasound in Obstetrics & Gynecology
Agustin Conde-Agudelo, José Villar, Stephen H Kennedy, Aris T Papageorghiou
OBJECTIVE: The cerebroplacental ratio (CPR) has been proposed for the routine surveillance of pregnancies with suspected fetal growth restriction (FGR), but the predictive performance of this test is unclear. The aim of this study was to determine the accuracy of the CPR for predicting adverse perinatal and neurodevelopmental outcomes in suspected FGR. METHODS: PubMed, EMBASE, CINAHL, and Lilacs (all from inception to July 31, 2017) were searched for cohort or cross-sectional studies that reported on the accuracy of the CPR for predicting adverse perinatal and/or neurodevelopmental outcomes in singleton pregnancies with antenatally suspected FGR based on sonographic parameters...
June 19, 2018: Ultrasound in Obstetrics & Gynecology
Angharad Care, Bertram Muller-Myhsok, Elena Olearo, Tullia Todros, Javier Caradeux, Maria Goya, Montse Palacio, Elena Carreras, Zarko Alfirevic
OBJECTIVE: The aim of this study was to investigate whether the classification of a previous spontaneous preterm birth (sPTB) into; i) sPTB or ii) PPROM, impacts the efficacy of cervical pessary or vaginal progesterone in pregnant women with short cervix on transvaginal ultrasound. METHODS: Four European hospitals using pessary or vaginal progesterone as a primary PTB prevention treatment for asymptomatic high-risk singletons with a short cervix, provided retrospective cohort data...
June 19, 2018: Ultrasound in Obstetrics & Gynecology
Daniel L Rolnik, Fabricio da Silva Costa, Daljit Sahota, Jon Hyett, Andrew McLennan
AIM: To assess the quality of mean uterine artery pulsatility index (UtAPI) measurement in a first trimester pre-eclampsia screening program. METHODS: Consecutive patients attending first trimester screening for fetal chromosomal abnormalities also had combined screening for pre-eclampsia based on the Fetal Medicine Foundation (FMF) algorithm, in a large practice in Sydney, Australia, from May 2014 to February 2017. Distributions of mean UtAPI multiples of the median (MoM) on the logarithmic scale were plotted in relation to the normal median with 95% confidence interval (CI) for each operator and for each month...
June 19, 2018: Ultrasound in Obstetrics & Gynecology
Svetlana V Glinianaia, Judith Rankin, Asma Khalil, Julia Binder, Gareth Waring, Stephen N Sturgiss, Basky Thilaganathan, Therese Hannon
OBJECTIVES: To determine the prevalence of monochorionic monoamniotic (MCMA) twin pregnancies and to describe perinatal outcomes and clinical management of these pregnancies. METHODS: This multicentre cohort study used population-based data on MCMA twin pregnancies from 11 Northern Survey of Twin and Multiple Pregnancy (NorSTAMP) maternity units for the prevalence estimation of MCMA twinning. Pregnancy outcomes at <24 weeks' gestation, antenatal parameters and perinatal outcomes (from ≥24 weeks to the first 28 days of life) were analysed using combined data on pregnancies with confirmed MCMA chorionicity from the NorSTAMP and the Southwest Thames Region of London Obstetric Research Collaborative (STORK) multiple pregnancy cohort for 2000-2013...
June 13, 2018: Ultrasound in Obstetrics & Gynecology
Andrea Dall'Asta, Tullio Ghi, Giuseppe Rizzo, Annalisa Cancemi, Filomena Aloisio, Domenico Arduini, Giuseppe Pedrazzi, Francesc Figueras, Tiziana Frusca
INTRODUCTION: Doppler ultrasound has recently been suggested to identify subclinical placental functional impairment among normal sized term fetuses. The objective of this study was to evaluate the relationship between cerebroplacental ratio (CPR) measured in early labor and perinatal and delivery outcomes in a cohort of uncomplicated singleton term pregnancies. METHODS: This was a multicentre, prospective, observational study involving three Tertiary Centres. Low risk term pregnancies, as defined by the absence of any maternal morbidity and pregnancy complication and normal ultrasound and clinical screening of the fetal growth in the third trimester, with spontaneous onset of labor were included...
June 13, 2018: Ultrasound in Obstetrics & Gynecology
Min Yi Tan, Argyro Syngelaki, Liona C Poon, Daniel L Rolnik, Neil O'Gorman, Juan Luis Delgado, Ranjit Akolekar, Liountmila Konstantinidou, Maria Tsavdaridou, Slavyana Galeva, Ursula Ajdacka, Francisca S Molina, Nicola Persico, Jacques C Jani, Walter Plasencia, Elena Greco, George Papaioannou, Alan Wright, David Wright, Kypros H Nicolaides
OBJECTIVE: To examine the performance of screening for early-, preterm- and term-preeclampsia (PE) at 11-13 weeks' gestation by maternal factors and combinations of mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI), serum placental growth factor (PLGF) and serum pregnancy associated plasma protein-A (PAPP-A). METHODS: The data for this study were derived from three previously reported prospective non-intervention screening studies at 11+0 - 13+6 weeks' gestation in a combined total of 61,174 singleton pregnancies, including 1,770 (2...
June 13, 2018: Ultrasound in Obstetrics & Gynecology
Anca Panaitescu, Anca Ciobanu, Argyro Syngelaki, Alan Wright, David Wright, Kypros H Nicolaides
OBJECTIVE: To examine the performance of screening for preeclampsia (PE) at 35-37 weeks' gestation by maternal factors and combinations of mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI), serum placental growth factor (PLGF) and serum soluble fms-like tyrosine kinase-1 (sFLT). METHODS: This was a prospective observational study in women with singleton pregnancies attending for an ultrasound scan at 35+0 - 36+6 weeks as part of routine pregnancy care...
June 13, 2018: Ultrasound in Obstetrics & Gynecology
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