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Ultrasound in Obstetrics & Gynecology

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https://www.readbyqxmd.com/read/28940481/prevention-of-preterm-birth-with-pessary-in-singletons-popps-a-randomized-controlled-trial
#1
Lorraine Dugoff, Vincenzo Berghella, Harish Sehdev, A Dhanya Mackeen, Laura Goetzl, Jack Ludmir
OBJECTIVE: To determine if pessary use prevents preterm birth in singleton gestations with a short transvaginal ultrasound cervical length and without a prior spontaneous preterm birth. METHODS: In this open-label multicenter randomized trial we enrolled asymptomatic women with singleton gestations with a transvaginal ultrasound cervical length ≤ 25 mm at 18(0) -23(6) weeks and no prior spontaneous preterm birth. Subjects were randomized to receive the Bioteque cup pessary or no pessary...
September 20, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28926132/prenatal-diagnosis-of-total-and-partial-anomalous-pulmonary-venous-connection-multicentre-cohort-study-and-meta-analysis
#2
REVIEW
Dario Paladini, Angela Pistorio, L H Wu, Gabriella Meccariello, Ting Lei, Giulia Tuo, Gloria Donarini, Maurizio Marasini, Hong-Ning Xie
OBJECTIVES: Aim of this study is to describe the sonographic features and associations of Total and Partial Anomalous Pulmonary Venous Connection (TAPVC, PAPVC) and scimitar syndrome (SS) and to review the relevant literature systematically in order to underline the associations and the sonographic features more frequently associated with these conditions. METHODOLOGY: Retrospective cohort study. Assessed variables include: TAPVC subtype, gestational age at diagnosis, area behind LA, ventricular disproportion, vertical vein, pulmonary venous obstruction, mode of diagnosis, association with cardiac and extra-cardiac conditions, pregnancy and feto-neonatal outcome...
September 19, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28925589/recurrent-twin-twin-transfusion-syndrome-rttts-and-twin-anemia-polycythemia-sequence-taps-after-fetoscopic-laser-surgery-fls-size-of-the-cannula-does-matter
#3
Roopali Donepudi, Joost Akkermans, Lovepreet Mann, Frans J Klumper, Johanna M Middeldorp, Enrico Lopriore, Kenneth J Moise, Michael Bebbington, Anthony Johnson, Dick Oepkes, Ramesha Papanna
OBJECTIVES: Optimal outcomes after fetoscopic laser surgery (FLS) for twin-twin transfusion (TTTS) depend on the successful completion of ablation of all placental anastomoses. Our objective was to determine the incidence and risk factors for the occurrence of recurrent TTTS (rTTTS) or twin anemia-polycythemia sequence (TAPS) after FLS, and focusing on the impact of different diameters of the cannula. METHODS: A secondary analysis of prospectively collected data of 666 consecutive patients undergoing laser surgery for TTTS from 2 centers was performed...
September 19, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28925570/first-trimester-screening-based-on-ultrasound-and-cfdna-vs-first-trimester-combined-screening-a-randomized-controlled-study
#4
Karl Oliver Kagan, Fabrina Sroka, Jiri Sonek, Harald Abele, Kai Lüthgens, Maximilian Schmid, Philipp Wagner, Sara Brucker, Diethelm Wallwiener, Markus Hoopmann
OBJECTIVE: Prospective randomized trial to compare the performance of first trimester combined screening (FTCS) with an approach that uses the combination of a detailed ultrasound examination and cfDNA analysis. METHODS: Pregnant women with a normal first-trimester ultrasound examination at 11 to 13 weeks' gestation (fetal NT ≤3.5 mm and no fetal defects) were randomized into two groups. In the first group, the risk of aneuploidy was assessed using FTCS based on the most recent FMF UK algorithm...
September 19, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28925535/metastases-of-breast-cancer-to-a-uterine-leiomyoma
#5
LETTER
Manuela Ludovisi, Maria Cristina Moruzzi, Gabriella Ferrandina, Giovanni Scambia, Antonia Carla Testa
Metastases to the uterus occur very rarely, accounting for less than 10% of all cases of metastases involving the female genital tract; mammary and gastrointestinal carcinomas are the most frequent extragenital primary neoplasms metastasizing to the uterine corpus(1) . Very little data is available in the literature including 24 cases of breast cancer metastasized to a uterine leiomyoma(2) , as assessed at surgery (N = 16), and autoptic evaluation (n = 8).
September 19, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28887883/early-screening-and-prevention-of-preterm-preeclampsia-with-aspirin-time-for-clinical-implementation
#6
EDITORIAL
Daniel L Rolnik, Neil O'Gorman, Stephanie Roberge, Emmanuel Bujold, Jonathan Hyett, Serge Uzan, Michel Beaufils, Fabricio da Silva Costa
Despite all the research published in the last three decades on screening and prevention of preeclampsia (PE), this condition remains one of the main causes of maternal and perinatal morbidity and mortality, both in low and high-income countries. It affects 2-8% of all pregnancies, being responsible for one out of five maternal deaths and 15% of all premature deliveries(1) . An ideal screening test requires identification of women at high-risk of developing severe and early-onset forms of the disease, a high detection rate (DR) with an acceptable false-positive rate (FPR), and the availability of an effective preventive measure(2) ...
September 9, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28876497/automated-follicle-count-using-three-dimensional-ultrasound-in-polycystic-ovarian-morphology
#7
W Froyman, D Van Schoubroeck, D Timmerman
A 24-year-old nulligravida was referred for gynecological ultrasonography since she presented at the outpatient clinic with the complaint of secondary amenorrhea after stopping the combined oral contraceptive pill ten months before. Physical examination showed no abnormalities. Two-dimensional (2D) ultrasound (GE Voluson E10 Expert, GE Medical Systems, Zipf, Austria) showed a normal anteverted uterus with a regular and thin endometrium (double endometrial thickness 2 mm).
September 6, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28876491/longitudinal-changing-values-of-the-sflt-1-plgf-ratio-in-singleton-pregnancies-with-early-onset-fetal-growth-restriction
#8
I Herraiz, M S Quezada, J Rodriguez-Calvo, E Gómez-Montes, C Villalaín, A Galindo
OBJECTIVE: To describe, in singleton pregnancies complicated with early-onset fetal growth restriction (FGR), the progressing values of the sFlt-1/PlGF ratio in the weeks prior to delivery, differentiating cases with and without pre-eclampsia (PE). METHODS: Prospective cohort observational study of early-onset FGR cases followed with maternal serum determinations of the sFlt-1/PlGF ratio from diagnosis to delivery. Measurements were made at weekly intervals and within the last 48 hours before birth...
September 6, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28876490/fetal-intra-abdominal-umbilical-vein-varix-a-retrospective-cohort-study-systematic-review-of-the-literature-and-meta-analysis
#9
REVIEW
E di Pasquo, M Kuleva, N O'Gorman, Y Ville, L J Salomon
OBJECTIVES: To investigate the outcome of fetuses with intra-abdominal umbilical vein varix (FIUVV) METHODS: A retrospective cohort study of cases of FIUVV was carried out. Information retrieved included gestational age and diameter of the umbilical varix at diagnosis, increasing in varix diameter, associated ultrasound and chromosomal anomalies and pregnancy outcome. A systematic review and a meta-analysis of the existing literature were performed to assess the incidence of chromosomal anomalies, Small for Gestational Age (SGA) infants and Intra-Uterine Fetal Demise (IUFD) and to pool relative risk (OR) estimates on the relationship between the presence of associated additional ultrasound anomalies and the occurrence of these outcomes...
September 6, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28857365/functional-haemodynamic-testing-in-pregnancy-recommendations-of-the-international-working-group-on-maternal-haemodynamics
#10
Victoria L Meah, Karianne Backx, Margie H Davenport
In the general population, functional haemodynamic testing, such as submaximal aerobic exercise, isometric handgrip, and the cold pressor test, has long been utilised to unmask abnormalities in cardiovascular function. During pregnancy, functional haemodynamic testing places additional demands on an already stressed maternal cardiovascular system. Dysfunctional responses to such tests in early pregnancy may predict the development of hypertensive disorders that develop later in gestation. These recommendations cover a description, an overview of the current understanding of clinical application, test protocol, equipment and considerations of each of the above functional haemodynamic tests during pregnancy...
August 30, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28850758/ultrasound-based-three-dimensional-medical-model-printing-for-multispecialty-team-surgical-rehearsal-prior-to-fetoscopic-myelomeningocele-repair
#11
LETTER
J L Miller, E S Ahn, J R Garcia, G T Miller, A J Satin, A A Baschat
Recently a two-port open fetoscopic myelomeningocele (MMC) repair technique, performed together by a pediatric neurosurgeon and maternal-fetal medicine specialist was described.(1) Acquiring skills for this type of fetoscopic surgery is complex since MMC lesions are anatomically variable and collaboration of two surgical specialists is required. We utilized ultrasound-based 3D multi-material printing to generate a patient-matched medical model to prepare the surgical team for fetoscopic MMC repair.
August 29, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28850753/retrospective-cohort-study-of-pamg-1-and-fetal-fibronectin-test-performance-in-assessing-spontaneous-preterm-birth-risk-in-symptomatic-women-attending-an-emergency-obstetrical-unit
#12
J C Melchor, H Navas, M Marcos, A Iza, M de Diego, D Rando, I Melchor, J Burgos
OBJECTIVE: To assess the performance of the PAMG-1 and fFN tests using real-world data for the prediction of spontaneous preterm delivery (sPTD) in patients presenting to an emergency obstetrical unit with threatened preterm labour (PTL) by conducting a retrospective audit of patient medical records over two different one-year time periods during which either fFN or PAMG-1 was used as the standard of care biochemical test. METHODS: A retrospective cohort study chart review of women with threatened PTL electronic medical records (EMR) from a Level III maternity hospital was conducted for two periods of one year each: (1) the "Baseline" time period, during which the qualitative fFN test with a cutoff of 50 ng/ml was used as standard of care biochemical test for the risk assessment of preterm delivery, and (2) the "Comparative" time period, during which the PAMG-1 test with a cutoff of 1 ng/mL was used as the standard of care biomarker test...
August 29, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28850746/screening-for-pre-eclampsia-in-the-first-trimester-what-do-we-still-need-to-know-before-starting
#13
LETTER
Federico Prefumo, Antonio Farina
In the last years, many papers reported model building and validation and studies of first trimester pre-eclampsia (PE) screening algorithms (1-4) . They basically offer a multivariable panel of predictors and some equations able to estimate the a posteriori risk for different phenotypes of PE, including early and late PE. The predictors include a set of "maternal factors" and a step by step addition of uterine artery pulsatility index (Ut-A PI), maternal mean arterial pressure (MAP) and biochemical markers...
August 29, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28833750/first-trimester-detection-of-abnormally-invasive-placenta-in-women-at-risk-a-systematic-review-and-meta-analysis
#14
REVIEW
Francesco D'Antonio, Ilan E Timor-Trisch, Josè Palacios-Jaraquemada, Ana Monteagudo, Danilo Buca, Francesco Forlani, Gabriella Minneci, Francesca Foti, Lamberto Manzoli, Marco Liberati, Ganesh Acharya, Giuseppe Calì
OBJECTIVES: The primary aim of this systematic review was to ascertain whether ultrasound (US) signs suggestive of abnormally invasive placenta (AIP) are present in the first trimester. The secondary aims were to ascertain the strength of association and the predictive accuracy of such signs in detecting AIP in the first trimester of pregnancy. METHODS: MEDLINE, EMBASE, CINAHL and Cochrane databases (2000-2016) were searched. Only studies reporting the first trimester diagnosis of AIP that was subsequently confirmed in the third trimester either during operative delivery or by pathology were included...
August 21, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28833712/cell-free-fetal-dna-analysis-in-maternal-plasma-as-a-screening-test-for-trisomy-21-18-and-13-in-twin-pregnancies
#15
Grégoire Le Conte, Alexandra Letourneau, Jacques Jani, Pascale Kleinfinger, Laurence Lohmann, Jean-Marc Costa, Alexandra Benachi
OBJECTIVES: To evaluate the utility of noninvasive prenatal testing using cell-free circulating fetal DNA (cfDNA) in screening for the three main autosomal fetal trisomies in twin pregnancies. METHODS: CfDNA testing was offered to 492 patients with twin pregnancies without ultrasound anomalies as a first-line screening test or after serum screening in clinical practice. Data were collected prospectively and a retrospective analysis was performed. CfDNA analysis was performed by massively parallel sequencing...
August 18, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28833701/microvascular-imaging-of-thick-placenta-with-fetal-growth-restriction
#16
LETTER
Toshiyuki Hata, Kenji Kanenishi, Kenta Yamamoto, Mohamed Ahmed Mostafa AboEllail, Masato Mashima, Nobuhiro Mori
Seven normal pregnancies at 11-34 weeks and three cases of a thick placenta with fetal growth restriction (FGR) at 19, 31, and 33 weeks were studied to assess placental vascularity using two-dimensional (2D)/three-dimensional (3D)-SMI (Aplio 800 or i900, Toshiba Medical Systems, Tokyo, Japan).
August 18, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28833651/major-cardiac-defects-and-placental-dysfunction-at-11-13-weeks-gestation
#17
Ilaria Fantasia, Dila Kasapoglu, Taner Kasapoglu, Argyro Syngelaki, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVES: To investigate the relationship between fetal major cardiac defects and markers of placental perfusion and function. METHODS: This was a prospective screening study in singleton pregnancies at 11-13 weeks' gestation. Uterine artery pulsatility index (UTPI), serum pregnancy associated plasma protein-A (PAPP-A) and placental growth factor (PLGF) were measured and the values were converted into multiples of the normal median (MoM). Median MoM values in fetuses with isolated major cardiac defects were compared to those in fetuses without major defects...
August 18, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28809063/color-and-power-doppler-combined-with-fetal-intelligent-navigation-echocardiography-fine-to-evaluate-the-fetal-heart
#18
L Yeo, R Romero
OBJECTIVE: To evaluate the performance of color and bidirectional power Doppler ultrasound combined with Fetal Intelligent Navigation Echocardiography (FINE) in examining the fetal heart. METHODS: A prospective cohort study was conducted of fetuses in the second and third trimesters with a normal heart or with congenital heart disease (CHD). One or more spatiotemporal image correlation (STIC) volume datasets, combined with color or bidirectional power Doppler (S-flow) imaging, were acquired in the apical four-chamber view...
August 14, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28796394/maternal-haemodynamics-in-normal-pregnancies-and-in-pregnancies-affected-by-pre-eclampsia
#19
Daniel Stott, Obianuju Nzelu, Kypros H Nicolaides, Nikos A Kametas
OBJECTIVES: To determine if in a high risk group in the first half of pregnancy, women who developed pre-eclampsia (PE) with fetal growth restriction (PE-FGR) demonstrate distinct haemodynamics compared to those with PE in the absence of FGR (PE-only). METHODS: Cardiac output (CO), peripheral vascular resistance (PVR) and mean arterial pressure (MAP) were measured at the first hospital visit at 9-24 weeks' gestation in 69 women who had chronic hypertension and 67 who had a hypertensive disorder in a previous pregnancy...
August 10, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28796383/self-reported-transvaginal-ultrasound-visualization-of-normal-ovaries-in-postmenopausal-women-is-not-reliable-results-of-expert-review-of-archived-images-in-ukctocs
#20
Will Stott, Stuart Campbell, Angelo Franchini, Oleg Blyuss, Alexey Zaikin, Andy Ryan, Chris Jones, Aleksandra Gentry-Maharaj, Gwendolen Fletcher, Jatinderpal Kalsi, Steve Skates, Max Parmar, Nazar Amso, Ian Jacobs, Usha Menon
OBJECTIVE: In UKCTOCS self-reported visualization rates(srVR) at annual TVS scan was a key quality control(QC) metric. Our objective was to independently assess srVR using expert review and develop software capable of monitoring it. METHODS: Images from 1,000 examinations randomly selected from 68,951 archived annual TVS exams undertaken between 2008-2011 where the ovaries were reported as 'seen and normal' were reviewed by a single expert. Software was developed to identify exact images used to measure ovaries by measuring caliper dimensions and matching them to that recorded by the sonographer...
August 10, 2017: Ultrasound in Obstetrics & Gynecology
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