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Ultrasound in Obstetrics & Gynecology

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https://www.readbyqxmd.com/read/28543953/improved-technical-success-postnatal-outcomes-and-refined-predictors-of-outcome-for-fetal-aortic-valvuloplasty
#1
Kevin G Friedman, Lynn A Sleeper, Lindsay R Freud, Audrey C Marshall, Max E Godfrey, Monika Drogosz, Terra Lafranchi, Carol B Benson, Louise E Wilkins-Haug, Wayne Tworetzky
BACKGROUND: Fetal aortic valvuloplasty (FAV) may prevent progression of mid-gestation aortic stenosis (AS) to hypoplastic left heart syndrome (HLHS). METHODS: We evaluate outcomes in 123 fetuses that underwent FAV between 2000 and 2015. We analyze whether technical success and biventricular (Biv) outcome changed from the early era (2000-08) to a more recent era (2009-15) and identify pre-FAV predictors of Biv outcome. We developed CART models to predict the likelihood of Biv outcome...
May 22, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508399/hdliveflow-with-spatiotemporal-image-correlation-for-the-diagnosis-of-congenital-heart-disease
#2
Megumi Ito, Mohamed Ahmed Mostafa AboEllail, Kenta Yamamoto, Kenji Kanenishi, Hirokazu Tanaka, Hiroshi Masaoka, Toshiyuki Hata
With the latest advancement of three-dimensional (3D)/four-dimensional (4D) ultrasound machines, HDliveFlow will facilitate more precise evaluations of the fetal and placental circulations [1-5] and gynecologic disorders [6-10]. HDliveFlow silhouette mode is the latest technology to demonstrate vitreous-like clarity of the blood flow. This technique has the ability to preserve and delineate the outline and borders of the blood flow, while showing its core as transparent.
May 16, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508549/prenatal-prediction-of-postnatal-large-for-date-neonates-using-a-simplified-method-at-mr-imaging-comparison-with-conventional-2d-ultrasound-estimates
#3
Caroline Kadji, Mieke M Cannie, Ricardo De Angelis, Margaux Camus, Magdalena Klass, Stéphanie Fellas, Vera Cecotti, Vivien Dütemeyer, Jacques C Jani
PURPOSE: To evaluate the performance of a simple method of estimating fetal weight (EFW) using MR imaging as compared with 2D US in the prediction of large-for-date neonates. MATERIALS & METHODS: Written informed consent was obtained for this EC-approved study. Between March 2011 and May 2016, 2 groups of women with singleton pregnancies were evaluated: women that underwent US-EFW and MR-EFW within 48 h before delivery and those undergoing these evaluations between 35 + 0 weeks and 37 + 6 weeks of gestation...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508540/fetal-recurrent-thyrotoxicosis
#4
LETTER
Carlota Rodó, Francesca Deambrogio, Laura Serra, Sílvia Pina, Mª Ángeles Sánchez-Duran
Fetal hyperthyroidism is a rare and potentially life-threatening condition, not always easy to detect(1,2) . It is most commonly observed in maternal thyroid autoimmune disorders such as poorly controlled Grave's disease. Transplacental passage of maternal thyroid stimulating immunoglobulins (TSI) is the main cause of fetal thyroid gland stimulation and the clinical manifestations of this disorder: intrauterine growth restriction, non-immune hydrops, fetal goiter, tachycardia, craniosynostosis, accelerate bone maturation and intrauterine death(2) ...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508528/competing-risks-model-in-screening-for-preeclampsia-in-twin-pregnancies-by-maternal-characteristics-and-medical-history
#5
Carla Francisco, David Wright, Zsófia Benkő, Argyro Syngelaki, Kypros H Nicolaides
OBJECTIVE: A survival-time regression model for the gestational age at delivery with preeclampsia (PE) in singleton pregnancies using maternal demographic characteristics and medical history was previously reported. The objective of this paper is to extend this model for dichorionic (DC) and monochorionic (MC) twin pregnancies. METHODS: The study population included 1,789 DC and 430 MC twin pregnancies and 93,297 singleton pregnancies. A survival-time model for the gestational age at delivery with PE was developed from variables of maternal characteristics and history...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508519/fetal-cardiac-remodeling-in-twin-pregnancies-conceived-by-assisted-reproductive-technologies
#6
Brenda Valenzuela-Alcaraz, Mónica Cruz-Lemini, Mérida Rodríguez-López, Ana Goncé, Laura García-Otero, Helena Ayuso, Marta Sitges, Bart Bijnens, Juan Balasch, Eduard Gratacós, Fátima Crispi
BACKGROUND: Recent data suggest that singleton fetuses conceived by assisted reproductive technologies (ART) present cardiovascular remodeling that may persist postnatally. Twin pregnancies are more frequent in the ART population, and are associated with increased adverse perinatal outcomes like hypertensive disorders, gestational diabetes and preterm birth. However, it is unknown whether cardiac remodeling is also present in twin pregnancies conceived by ART. Our aim was to assess the presence of fetal cardiac remodeling and dysfunction in twin pregnancies conceived by ART, as compared to spontaneously conceived (SC) ones...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508434/maternal-arterial-stiffness-and-fetal-cardiovascular-physiology-in-diabetic-pregnancies
#7
Shreya Moodley, Alisa Arunamata, Katie Jo Stauffer, Susan E Nourse, Angela Chen, Amy Quirin, Elif Seda Selamet Tierney
OBJECTIVES: In mothers with pre-gestational or gestational diabetes, abnormal arterial stiffness (stiffer arteries) has been reported. The impact of abnormal maternal arterial stiffness on fetal placental and cardiovascular physiology is unknown. The purpose of the study was to determine the impact of maternal diabetes on maternal arterial stiffness and the association with fetal cardiovascular physiology as measured by fetal echocardiography. METHODS: Between December 2013 and January 2017 we conducted a prospective study on diabetic (otherwise healthy) and non-diabetic, healthy pregnant mothers (at 20-28 gestational weeks and 18-40 years of age) who had a normal fetal cardiac echocardiogram and obstetric ultrasound...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508426/the-role-of-transvaginal-ultrasound-in-the-evaluation-of-ureteral-involvement-in-deep-endometriosis
#8
P Carfagna, C De Cicco Nardone, A De Cicco Nardone, A C Testa, G Scambia, R Marana, F De Cicco Nardone
OBJECTIVE: To assess whether routine visualization of the pelvic ureter during transvaginal ultrasonography should be performed in all patients with deep endometriosis candidate to surgery, in order to identify a potential silent ureteral involvement by the disease. METHODS: This was a prospective study of 200 consecutive patients undergoing surgery for deep endometriosis, evaluated between January 2012 and December 2014 at a tertiary endometriosis center at the Department of Obstetrics and Gynecology, Fondazione Policlinico Universitario A...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28508418/quantitative-analysis-of-the-cervical-texture-by-ultrasound-in-the-mid-pregnancy-is-associated-with-spontaneous-preterm-birth
#9
Núria Baños, Alvaro Perez-Moreno, Carla Julià, Clara Murillo-Bravo, David Coronado, Eduard Gratacos, Jan Deprest, Montse Palacio
OBJECTIVE: New tools are required to identify women at increased risk of spontaneous preterm birth (sPTB). Quantitative texture analysis by ultrasound has been used to extract robust features from the ultrasound image of a given tissue to detect subtle changes in its microstructure. This may also be applied to the cervix. We aimed to determine if there is an association between quantitative analysis of the cervical texture (CTx) by ultrasound in the mid-trimester of pregnancy and sPTB <37(+0) weeks...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28477345/fetoscopic-laser-coagulation-in-1020-pregnancies-with-twin-to-twin-transfusion-syndrome-demonstrates-improvement-of-double-survival-rates
#10
W Diehl, A Diemert, D Grasso, S Sehner, K Wegscheider, K Hecher
OBJECTIVE: To investigate the growing experience and learning curve of fetoscopic laser coagulation of the placental vascular anastomoses in severe mid trimester twin-to-twin transfusion syndrome (TTTS) and its influence on perinatal outcome in a single center setting. METHODS: Between 01/1995 and 03/2013 we performed laser therapy in 1020 consecutive pregnancies with TTTS between 15.1 and 27.4 weeks of gestation. We compared perinatal outcome in blocks of five sequential groups...
May 6, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28470791/impaired-placentation-in-women-with-chronic-hypertension-that-develop-preeclampsia
#11
Anca M Panaitescu, Ranjit Akolekar, Nicholas Kametas, Argyro Syngelaki, Kypros H Nicolaides
OBJECTIVE: To compare the degree of impaired placentation in pregnancies which develop preeclampsia (PE) in women with and without chronic hypertension (CH). METHODS: The data for this study were derived from prospective screening for adverse pregnancy outcomes in women with singleton pregnancies attending for their first routine hospital visit at 11(+0) -13(+6) weeks' gestation. This visit included recording of maternal characteristics and medical history and measurements of mean arterial pressure (MAP), uterine artery pulsatility index (UTPI), serum placental growth factor (PLGF) and serum pregnancy associated plasma protein-A (PAPP-A)...
May 4, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28466998/cardiac-remodelling-and-preeclampsia-an-overview-of-overlapping-circulating-mirnas
#12
Zenab Mohseni, Marc E A Spaanderman, Jolien Oben, Martina Calore, Elianne Derksen, Salwan Al-Nasiry, Leon de Windt, Chahinda Ghossein-Doha
OBJECTIVES: Preeclampsia (PE) is strongly associated with heart failure (HF) later in life. During preeclamptic pregnancy the left ventricle (LV) remodels in a concentric way. This aberrant remodelling often persists after delivery. The concentric remodelling during PE can induce molecular signatures that may explain the associated increased risk of HF. This signature may be evaluated in terms of microRNAs (miRNAs). This review evaluates existing literature on miRNA expression data in concentric remodelling on the one hand and PE on the other to generate a list of overlapping miRNA expression patterns in both...
May 3, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28452161/perinatal-outcome-and-placental-apoptosis-in-patients-with-late-onset-pre-eclampsia-and-abnormal-uterine-artery-doppler-at-diagnosis
#13
Marcelo Rodríguez, Constanza Couve-Pérez, Sebastián San Martín, Felipe Martínez, Carlo Lozano, Alvaro Sepúlveda-Martínez
OBJECTIVE: To determine the rate of placental apoptosis and adverse perinatal outcome in patients with late pre-eclampsia and altered uterine artery (UtA) Doppler. METHODS: A cohort study was performed. Patients with a diagnosis of late pre-eclampsia (l-PE) were stratified according to the UtA Doppler status at diagnosis (below or above the 95(th) percentile). A logistic regression analysis was performed to identify the association between an abnormal UtA Doppler and the presence of adverse maternal and perinatal outcomes...
April 28, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28452133/blinded-ultrasonic-fetal-biometry-at-36-weeks-and-the-risk-of-emergency-caesarean-delivery-a-prospective-cohort-study-of-3-047-low-risk-nulliparous-women
#14
Ulla Sovio, Gordon C S Smith
OBJECTIVES: We studied the risk of emergency caesarean delivery (CD) using blinded ultrasonographic estimated fetal weight (EFW) at 36 weeks of gestational age (wkGA): (1) to compare the association for customised and non-customised EFW, (2) to determine whether adding ultrasonic EFW improved prediction based on maternal characteristics alone, and (3) to determine whether women at high predicted risk of emergency CD had higher risks of maternal and perinatal morbidity than other women...
April 28, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28452092/prospective-assessment-of-the-intergrowth-21-and-who-estimated-fetal-weight-reference-curve
#15
Yvonne Kwun Yue Cheng, Jing Lu, Tak Yeung Leung, Yiu Man Chan, Daljit Singh Sahota
OBJECTIVES: To assess the suitability of the new INTERGROWTH-21 and WHO estimated fetal weight (EFW) references. METHODS: This was a prospective cross-sectional cohort study. Viable singleton pregnancies at 11-13 weeks were randomized to undergo a standardized fetal biometric scan after 20 weeks. EFW were predicted using both the Hadlock and INTERGROWTH-21 weight estimation models formulaes. Population specific EFW gestation references were constructed. Z-scores were used to compare the population specific reference against the two international size references, INTERGROWTH-21 and WHO...
April 28, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28452086/the-effects-of-nifedipine-and-atosiban-on-perinatal-brain-injury-a-secondary-analysis-of-the-apostel-iii-trial
#16
T A J Nijman, M M Goedhart, C N Naaktgeboren, T R de Haan, D C Vijlbrief, B W Mol, M J N Benders, A Franx, M A Oudijk
OBJECTIVE: Brain injury in prematurely born neonates is strongly associated with poor neurodevelopmental outcome. The aim of our study is to evaluate if nifedipine reduces overall brain injury compared to atosiban in women with threatened preterm birth. METHODS: We performed a secondary analysis of the APOSTEL III-trial (Dutch Clinical Trial Registry, number NTR2947). This was a randomized clinical trial that allocated women with threatened preterm labor between 25-34 weeks of gestation to nifedipine or atosiban...
April 28, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28437601/maternal-hemodynamics-in-normal-pregnancies-reference-ranges-and-the-role-of-maternal-characteristics
#17
Dimuthu Vinayagam, Baskaran Thilaganathan, Oliver Stirrup, Elena Mantovani, Asma Khalil
OBJECTIVES: The main aim of this study was to construct reference ranges of the maternal central hemodynamic parameters during pregnancy. The second aim was to determine the maternal and pregnancy characteristics, which influence these hemodynamic parameters. METHODS: This was a prospective cohort study of low-risk pregnant women attending for routine antenatal care at St George's Hospital, London. The exclusion criteria included any medical disorder present at the time of study recruitment, or development of hypertension or intrauterine fetal growth restriction following study recruitment...
April 24, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28437575/the-24-segment-sphericity-index-a-new-technique-to-evaluate-fetal-cardiac-diastolic-shape
#18
Greggory R DeVore, Berthold Klas, Gary Satou, Mark Sklansky
INTRODUCTION: Because of parallel circulation in the fetus and the differential effect various disease states may have on the shape of the right and left ventricles, this study was conducted to evaluate the Sphericity Index (SI) of 24 transverse segments distributed from the base to the apex of the ventricular chambers. METHODS: Two hundred control fetuses were examined between 20 and 40 weeks of gestation. The displacement of the ventricular endocardium during the cardiac cycle was computed using offline software...
April 24, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28436615/prenatal-2d-and-3d-4d-ultrasound-diagnosis-of-coronary-artery-fistula
#19
LETTER
I Tekesin, F Uhlemann
A coronary artery fistula (CAF) is an abnormal connection between a coronary artery and a cardiac chamber or great vessel.(1) Modern ultrasound techniques can assist in prenatal detection of CAF. We describe a case of an isolated left CAF draining into the right atrium that was detected using 4D colour Doppler with glass-body rendering mode and spatio-temporal image correlation (STIC).
April 24, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28436562/anatomical-subgroup-analysis-of-the-meridian-cohort-failed-commissuration
#20
Paul D Griffiths, Karen Brackley, Michael Bradburn, Daniel Ja Connolly, Mary L Gawne-Cain, Daniel I Griffiths, Mark D Kilby, Laura Mandefield, Cara Mooney, Stephen C Robson, Brigitte Vollmer, Gerald Mason
OBJECTIVE: To assess the contribution of in utero magnetic resonance (iuMR) imaging in fetuses diagnosed with either agenesis of the corpus callosum or hypogenesis of the corpus callosum (grouped as failed commissuration) on antenatal ultrasonography (USS) from the MERIDIAN cohort. METHODS: We report a sub-group analysis of fetuses with failed commissuration diagnosed on USS (with or without ventriculomegaly) from the MERIDIAN study who had iuMR imaging within 2 weeks of USS and outcome reference data were available...
April 24, 2017: Ultrasound in Obstetrics & Gynecology
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