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Trends in Cardiovascular Medicine

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https://www.readbyqxmd.com/read/28185709/heart-failure-guidelines-what-s-new
#1
REVIEW
Lampros Papadimitriou, Carine E Hamo, Javed Butler
Heart Failure is a global epidemic, affecting approximately 5 million adults in the U.S.A. The cornerstone of contemporary pharmacological therapy targets the over activated renin-angiotensin-aldosterone and sympathetic autonomic systems. The 2016 focused pharmacologic update on the current Heart Failure Guidelines introduces the use of two newly approved regimens valsartan/sacubitril and ivabradine. Over the last two decades, guideline directed medical therapy has accomplished significant improvement in survival rates among heart failure patients; however these novel compounds were reported to exert additional mortality and morbidity benefits, in heart failure subpopulations with reduced ejection fraction...
January 11, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28189476/editorial-to-discovery-of-a-murine-model-of-clinical-pulmonary-arterial-hypertension-mission-impossible-by-dai-and-zhao
#2
EDITORIAL
Gerald J Maarman
No abstract text is available yet for this article.
January 10, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28188081/sleep-disordered-breathing-and-cardiovascular-outcomes-is-it-time-to-change-our-thinking
#3
EDITORIAL
Maria R Bonsignore
No abstract text is available yet for this article.
January 6, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28161146/dietary-strategies-for-cardiovascular-health
#4
REVIEW
Brad P Dieter, Katherine R Tuttle
Cardiovascular disease is developed across a lifetime accumulation of risk. Numerous independent and synergistic cardiovascular risk factors can be induced by unhealthy dietary patterns. Epidemiological, mechanistic, clinical, and translational research point to refined sugars, processed and fatty meats, synthetic oils, and sodium as major dietary risk factors. The purpose of this review is to integrate these learnings into key principles for dietary frameworks aimed at improving overall cardiovascular health...
December 31, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28129967/l5-an-ldl-fraction-in-which-pathogenic-activity-of-ldl-is-concentrated
#5
EDITORIAL
Tatsuya Sawamura, Yoshiko Fujita, Sayaka Horiuchi, Akemi Kakino
No abstract text is available yet for this article.
December 22, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28110794/towards-improved-understanding-of-atrial-fibrillation-in-south-asians
#6
EDITORIAL
Rajiv Mahajan, Dennis H Lau
No abstract text is available yet for this article.
December 21, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28143688/sleep-apnea-state-of-the-art
#7
REVIEW
Martin R Cowie
Many patient with, or at risk of, cardiovascular disease have sleep disordered breathing (SDB), which can be either obstructive (with intermittent collapse of the upper airway) or central (episodic loss of respiratory drive). SDB is associated with sleep disturbance, hypoxemia, hemodynamic changes, and sympathetic activation. Such patients have a worse prognosis than those without SDB. Mask-based therapies of positive airway pressure targeted at SDB can improve measures of sleep quality and partially normalize the sleep and respiratory physiology, but recent randomized trials of cardiovascular outcomes in SDB have either been neutral (obstructive sleep apnea) or suggested the possibility of harm, likely from increased sudden death, in central sleep apnea...
December 20, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28089339/discovery-of-a-murine-model-of-clinical-pah-mission-impossible
#8
REVIEW
Zhiyu Dai, You-Yang Zhao
Pulmonary arterial hypertension (PAH) is a lung vascular disease characterized with a progressive increase of pulmonary vascular resistance and obliterative pulmonary vascular remodeling resulting in right heart failure and premature death. In this brief review, we document the recent advances in identifying genetically modified murine models of PH, with a focus on the recent discovery of the mouse model of Tie2 Cre-mediated deletion of prolyl hydroxylase 2, which exhibits progressive obliterative vascular remodeling, severe PAH, and right heart failure, thus recapitulating many of the features of clinical PAH...
December 15, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28089202/cryoballoon-ablation-versus-radiofrequency-ablation-for-atrial-fibrillation
#9
REVIEW
Bruno Reissmann, Andreas Metzner, Karl-Heinz Kuck
No abstract text is available yet for this article.
December 14, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28108086/long-term-risk-of-wolff-parkinson-white-pattern-and-syndrome
#10
REVIEW
Susan S Kim, Bradley P Knight
For years, conventional wisdom has held that patients with asymptomatic ventricular pre-excitation (asymptomatic WPW or WPW pattern) were at low risk for adverse outcomes. This assumption has been challenged more recently in a number of observational/natural history studies as well as in prospective trials in which patients were more aggressively studied via invasive electrophysiology study (EPS) and more aggressively treated, in some cases, with pre-emptive catheter ablation, despite the lack of symptoms. In sum, the data do not definitively support one approach (early, up-stream EPS and/or ablation) vs...
December 5, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28040325/why-are-south-asians-seemingly-protected-against-the-development-of-atrial-fibrillation-a-review-of-current-evidence
#11
REVIEW
James O'Neill, Muzahir H Tayebjee
Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia and is strongly associated with conditions such as valvular heart disease, coronary artery disease and particularly hypertension and diabetes mellitus. The South Asian ethnic group have high rates of these conditions and so would be expected to be at significant risk of AF. However, observational studies have consistently shown that South Asians have a lower prevalence of AF compared with Caucasians. This article summarizes current evidence surrounding the development of AF and its relationship to ethnicity, offers potential reasons for this disparity and identifies future areas of research...
November 25, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28107840/my-approach-to-managing-statin-associated-muscle-symptoms
#12
Paul D Thompson
No abstract text is available yet for this article.
February 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28107839/my-approach-to-the-patient-with-memory-loss-who-needs-a-statin
#13
Karol E Watson, Tamer Sallam
No abstract text is available yet for this article.
February 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27612553/impact-of-empagliflozin-in-patients-with-diabetes-and-heart-failure
#14
REVIEW
David Pham, Natalia De Albuquerque Rocha, Darren K McGuire, Ian J Neeland
Heart failure (HF) is a common disease with increased risk for mortality and morbidity among patients with type 2 diabetes mellitus (T2DM). Optimal glycemic control in this patient population is challenging as many available therapies can potentially exacerbate symptoms of HF. Empagliflozin is one in a novel class of agents, the sodium glucose co-transporter 2 (SGLT2) inhibitors, that lowers blood glucose by increasing urinary glucose excretion and improves glycemic control and lowers body weight and blood pressure...
February 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27612551/cardiovascular-disease-in-patients-with-rheumatoid-arthritis
#15
REVIEW
Katherine P Liao
The risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) is 1.5-2-fold higher than age- and sex-matched individuals from the general population. This excess risk is attributed to the systemic chronic inflammation which is a hallmark of RA. Challenges to optimizing CV risk management in RA include the need for improved methods to predict CV risk, and defining the target risk factor(s) to reduce CV risk. Lessons learned from RA studies can also inform CV risk prevention in the general population, where inflammation also has an important role in the pathogenesis of atherosclerosis...
February 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27576060/biomarkers-in-cardiovascular-disease-statistical-assessment-and-section-on-key-novel-heart-failure-biomarkers
#16
REVIEW
Ravi Dhingra, Ramachandran S Vasan
Cardiovascular disease (CVD) is a leading cause of death worldwide and continues to increase in prevalence compared to previous decades, in part because of the aging of the world population. Atherosclerotic CVD starts at a very young age and progresses over time allowing sufficient time for screening and early detection of the condition. Advances in biomarker research and developments related to CVD over the past 30 years have led to more sensitive screening methods, a greater emphasis on its early detection and diagnosis, and improved treatments resulting in more favorable clinical outcomes in the community...
February 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27989286/my-approach-to-the-surgeon-s-view-on-degenerative-mitral-regurgitation
#17
Christina M Vassileva
No abstract text is available yet for this article.
January 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27989285/my-approach-to-the-evaluation-of-restrictive-cardiomyopathy
#18
Craig R Asher, Allan L Klein
No abstract text is available yet for this article.
January 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27612552/editorial-commentary-the-holy-grail-of-atrial-fibrillation
#19
EDITORIAL
Faisal F Syed, Hakan Oral
No abstract text is available yet for this article.
January 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27591800/editorial-commentary-beyond-the-guidelines-to-expertise-in-precision-stroke-medicine
#20
EDITORIAL
David S Liebeskind
No abstract text is available yet for this article.
January 2017: Trends in Cardiovascular Medicine
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