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Trends in Cardiovascular Medicine

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https://www.readbyqxmd.com/read/30220638/the-obesity-paradox-in-cardiovascular-disease-deeper-phenotyping-to-get-to-the-heart-of-the-matter
#1
EDITORIAL
Abbi Lane-Cordova
No abstract text is available yet for this article.
September 6, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30219276/editorial-commentary-peripartum-cardiomyopathy-long-term-implications-of-treatment-and-management
#2
EDITORIAL
Arash Haghikia, Denise Hilfiker-Kleiner
No abstract text is available yet for this article.
September 6, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30219275/editorial-commentary-cardiometabolic-diseases-and-gut-microbiota-removing-the-veil
#3
EDITORIAL
Jaime A Riquelme, Catterina Ferreccio, Sergio Lavandero
No abstract text is available yet for this article.
September 4, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30205924/an-overview-of-current-and-emerging-devices-for-percutaneous-left-atrial-appendage-closure
#4
REVIEW
Danny H F Chow, Yam-Hong Wong, Jai-Wun Park, Yat-Yin Lam, Tom De Potter, Josep Rodés-Cabau, Lluis Asmarats, Marcus Sandri, Eleftherios Sideris, Trevor McCaw, Randall J Lee, Horst Sievert, Lars Søndergaard, Ole De Backer
Atrial fibrillation (AF) is common and is a prominent risk factor for ischemic stroke. Oral anticoagulant (OAC) therapy has been the main strategy for stroke prevention in AF patients; however, OAC therapy carries a bleeding risk and is not tolerated by all patients. Left atrial appendage (LAA) closure offers a non-pharmacological alternative for stroke prevention in patients with non-valvular AF. In this update, an overview of current and emerging LAA occluders is given - with special attention to the key design features of every single device and, if available, preclinical or clinical data...
August 30, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30172579/association-of-body-mass-index-with-mortality-in-cardiovascular-disease-new-insights-into-the-obesity-paradox-from-multiple-perspectives
#5
REVIEW
Jonathan Y Xia, Donald M Lloyd-Jones, Sadiya S Khan
Over the past 4 decades, prevalence of obesity has increased rapidly at both the national and global level and presents a major public health challenge. Obesity is associated with increased risk of morbidity from cardiovascular diseases. Data suggesting that the presence of obesity may be protective in individuals with clinically manifest cardiovascular disease have led to discussion of an "obesity paradox", stirring controversy and leading to unclear messaging regarding the true health risks of excess weight...
August 22, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30172578/the-role-of-gpcr-signaling-in-cardiac-epithelial-to-mesenchymal-transformation-emt
#6
REVIEW
Canan G Nebigil, Laurent Désaubry
Congenital heart disease is the most common birth defect, affecting 1.35 million newborns every year. Heart failure is a primary cause of late morbidity and mortality after myocardial infarction. Heart development is involved in several rounds of epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET). Errors in these processes contribute to congenital heart disease, and exert deleterious effects on the heart and circulation after myocardial infarction. The identification of factors that are involved in heart development and disease, and the development of new approaches for the treatment of these disorders are of great interest...
August 22, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30177249/pulmonary-vascular-disease-in-the-setting-of-heart-failure-with-preserved-ejection-fraction
#7
REVIEW
Andrea R Levine, Marc A Simon, Mark T Gladwin
Heart failure with preserved ejection fraction (HFpEF) is defined as clinical features of heart failure, ideally with biomarker evidence such as elevated plasma natriuretic peptide levels, in the setting of an ejection fraction (EF) greater than 50% and imaging evidence of diastolic left ventricular dysfunction [1,2]. In the absence of cardiac imaging or invasive hemodynamics, this is a clinical syndrome that is often indistinguishable from heart failure with reduced ejection fraction (HFrEF). HFpEF and HFrEF present with a cadre of comparable signs and symptoms including jugular venous distention, pulmonary rales on auscultation, breathlessness, orthopnea, exercise intolerance, exertional dyspnea, fatigue and peripheral edema...
August 17, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30195945/molecular-imaging-of-coronary-inflammation
#8
REVIEW
Matthieu Pelletier-Galarneau, Terrence D Ruddy
Coronary inflammation is related to atherosclerotic disease and, less frequently, systemic vasculitis. Regardless of the etiology, coronary inflammation is associated with adverse cardiac events. Molecular imaging with 18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET/CT) allows in vivo assessment of coronary inflammation and evaluation of response to therapy. The aim of this review is to give an update on the recent development of FDG-PET/CT, discuss the potential roles of coronary inflammation imaging, review the limitations of FDG-PET/CT imaging, and give an overview of the new tracers available for PET/CT plaque imaging...
August 10, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30143275/micrornas-in-diabetic-wound-healing-pathophysiology-and-therapeutic-opportunities
#9
REVIEW
Denizhan Ozdemir, Mark W Feinberg
Diabetic wound healing is an incompletely understood pathophysiological state. It comprises a range of potentially devastating and common complications of diabetes mellitus (DM) leading to intractable infections, lower extremity amputations, and associated cardiovascular morbidity and mortality. MicroRNAs (miRNAs) have emerged as important regulators in various physiological processes in health and disease through their ability to fine-tune cellular responses. Herein, we summarize the versatile roles of miRNAs implicated in diabetic wound healing in key stages including inflammation, angiogenesis, re-epithelialization, and remodeling...
August 8, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30126689/diagnostics-and-therapeutic-implications-of-gut-microbiota-alterations-in-cardiometabolic-diseases
#10
REVIEW
Gabriele G Schiattarella, Anna Sannino, Giovanni Esposito, Cinzia Perrino
Alterations in gut microbiota composition and its metabolic activity are emerging as one of the most powerful determinants of cardiovascular disease. Although our knowledge of the precise molecular mechanisms by which gut microbiota influences cardiometabolic homeostasis is still limited, a growing body of knowledge has recently been uncovered about the potential modulation of microbiome for cardiovascular diagnostic and therapeutic aspects. The multitude of interactions between the microorganisms inhabiting the digestive tract and the host has been recognized crucial in the development and progression of atherosclerosis, obesity, diabetes and hypertension...
August 7, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30122289/metabolic-effects-of-cardiovascular-drugs
#11
REVIEW
Gabriele Fragasso, Alberto Margonato, Roberto Spoladore, Gary D Lopaschuk
Prescription of cardiovascular drugs is aimed at preventing and treating morbid conditions affecting the cardiovascular system. However, apart from their primary therapeutic target, some of the ordinary drugs used in cardiology daily practice also have additional pharmacological actions. Among these ancillary actions, those primarily affecting global and cardiac metabolism deserve special attention. In fact, apart from primary cardiac metabolic diseases, most cardiovascular diseases are heavily influenced by the patient's metabolic status and adaptation to the disease itself...
August 7, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30100522/editorial-commentary-re-inventing-chronic-disease-management-as-a-service-medication-adherence-solutions-are-ground-zero
#12
EDITORIAL
Leslie A Saxon, Anjali Doshi
No abstract text is available yet for this article.
August 3, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30111492/peripartum-cardiomyopathy-diagnosis-management-and-long-term-implications
#13
REVIEW
Kathleen Stergiopoulos, Fabio V Lima
Peripartum cardiomyopathy (PPCM) is a potentially life-threatening pregnancy-associated disease that typically arises in the peripartum period. While the disease is relatively uncommon, its incidence is rising. It is a form of idiopathic dilated cardiomyopathy, defined as pregnancy-related left ventricular dysfunction, diagnosed either towards the end of pregnancy or in the months following delivery, in women without any other identifiable cause. The clinical presentation, diagnostic assessment and treatment usually mirror that of other forms of cardiomyopathy...
August 1, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30093228/ethnic-and-racial-disparities-and-differences-in-sudden-cardiac-death-burden-and-survival-how-do-we-close-the-gap
#14
EDITORIAL
Raul D Mitrani, Robert J Myerburg
No abstract text is available yet for this article.
July 30, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30104111/management-of-high-risk-cardiac-conditions-in-pregnancy-anticoagulation-severe-stenotic-valvular-disease-and-cardiomyopathy
#15
REVIEW
Emily Lau, Doreen DeFaria Yeh
Cardiovascular disease contributes to approximately one third of all maternal mortality and remains a significant source of peri‑ and postpartum morbidity. As more women at risk for and with cardiovascular disease are desiring pregnancy, it is imperative that general cardiologists and obstetricians participate collaboratively in preconception counseling and are more facile with management of these lesions during peri‑ and postpartum periods. This review aims to address this growing need and highlights the management strategies for some of the major high risk cardiac conditions encountered during pregnancy including anticoagulation, cardiomyopathies as well as severe mitral and aortic stenosis; aortopathy, pulmonary hypertension, and severe congenital heart lesions will not be addressed...
July 22, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30075906/editorial-commentary-sex-strokes-and-atrial-fibrillation
#16
EDITORIAL
Charlotte J Bai, Annabelle Santos Volgman
No abstract text is available yet for this article.
July 21, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30075907/editorial-commentary-a-chemically-complex-and-unique-beverage-the-wine
#17
EDITORIAL
Carmine Rocca, Tommaso Angelone
No abstract text is available yet for this article.
July 19, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30072095/editorial-commentary-blood-pressure-and-cognition-in-the-elderly
#18
EDITORIAL
Janice B Schwartz
No abstract text is available yet for this article.
July 19, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30057151/prevention-and-treatment-of-atrial-fibrillation-is-hyperuricemia-the-next-target
#19
EDITORIAL
Eric Black-Maier, James P Daubert
No abstract text is available yet for this article.
July 19, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30054231/oxidized-ldl-the-next-big-thing
#20
EDITORIAL
Kunal V Patel, Dharam J Kumbhani
No abstract text is available yet for this article.
July 19, 2018: Trends in Cardiovascular Medicine
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