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Trends in Cardiovascular Medicine

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https://www.readbyqxmd.com/read/29753636/coronary-arterial-calcification-a-review-of-mechanisms-promoters-and-imaging
#1
REVIEW
Jordan Andrews, Peter J Psaltis, Belinda A Di Bartolo, Stephen J Nicholls, Rishi Puri
Coronary artery calcification (CAC) was once thought to be a passive, degenerative, and quiescent development of disease. However, it has now been shown to be an active process associated with atherosclerosis that is stimulated by inflammatory pathways. Calcification forms within the intimal and medial layers of the vessel wall by way of mechanisms similar to bone development. A variety of imaging modalities have been used to identify and characterize CAC, from early microcalcifications to well-developed fibroatheromas that have calcified...
May 2, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29753635/weaving-palliative-care-into-the-fabric-of-heart-failure-management
#2
EDITORIAL
Garrick C Stewart
No abstract text is available yet for this article.
April 30, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29724586/evolving-paradigms-for-stroke-prevention-in-patients-with-atrial-fibrillation
#3
EDITORIAL
Jackson J Liang, Sanjay Dixit
No abstract text is available yet for this article.
April 23, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29703509/will-the-real-long-qt-genes-please-stand-up
#4
EDITORIAL
Belinda Gray, Christopher Semsarian
No abstract text is available yet for this article.
April 17, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29703508/genetic-testing-of-long-qt-syndrome-should-we-go-back-to-the-future
#5
EDITORIAL
Eugenio Cingolani
No abstract text is available yet for this article.
April 17, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29699854/use-of-software-applications-to-improve-medication-adherence-and-achieve-more-integrated-disease-management-in-heart-failure-a-review
#6
REVIEW
Guy Talmor, Benjamin Nguyen, Andrew Keibel, Tijana Temelkovska, Leslie Saxon
The treatment and management of heart failure is associated with high mortality rates and treatment costs. Poor medication adherence is a major barrier to improving care and traditional interventions addressing non-adherence have not consistently demonstrated improvement in health care outcomes like readmission. The reasons for non-adherence are complicated and illustrate the broader challenges patients face when managing a complex disease like heart failure. In this review, a digitally enabled heart failure management platform consisting of medical digital tools and software solutions that are designed to be patient-facing and continuously accessed is explored as a way to integrate the multiple components of heart failure care and deliver personalized patient management tools...
April 17, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29739702/contemporary-approach-to-stroke-prevention-in-atrial-fibrillation-risks-benefits-and-new-options
#7
REVIEW
Jonathan Stock, Brian J Malm
Atrial fibrillation is a common diagnosis affecting nearly 3 million adults in the United States. Morbidity and mortality in these patients is driven largely by the associated increased risk of thromboembolic complications, especially stroke. Atrial fibrillation is a stronger risk factor than hypertension, coronary disease, or heart failure and is associated with an approximately five-fold increased risk. Mitigating stroke risk can be challenging and requires accurate assessment of stroke risk factors and careful selection of appropriate therapy...
April 4, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29661707/the-genetic-architecture-of-long-qt-syndrome-a-critical-reappraisal
#8
REVIEW
John R Giudicessi, Arthur A M Wilde, Michael J Ackerman
Collectively, the completion of the Human Genome Project and subsequent development of high-throughput next-generation sequencing methodologies have revolutionized genomic research. However, the rapid sequencing and analysis of thousands upon thousands of human exomes and genomes has taught us that most genes, including those known to cause heritable cardiovascular disorders such as long QT syndrome, harbor an unexpected background rate of rare, and presumably innocuous, non-synonymous genetic variation. In this Review, we aim to reappraise the genetic architecture underlying both the acquired and congenital forms of long QT syndrome by examining how the clinical phenotype associated with and background genetic variation in long QT syndrome-susceptibility genes impacts the clinical validity of existing gene-disease associations and the variant classification and reporting strategies that serve as the foundation for diagnostic long QT syndrome genetic testing...
March 30, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29661710/nox2-a-new-challenge-for-antiplatelet-treatment
#9
EDITORIAL
Francesco Violi
No abstract text is available yet for this article.
March 28, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29661712/nadph-oxidase-2-nox2-a-key-target-of-oxidative-stress-mediated-platelet-activation-and-thrombosis
#10
REVIEW
Eduardo Fuentes, Jonathan M Gibbins, Lisa M Holbrook, Iván Palomo
Oxidative stress represents an imbalance between the production of reactive oxygen species (ROS) and the cellular antioxidant system. Increased levels of oxidative stress contribute to the development of atherosclerosis that eventually leads to thrombosis; a principle cause of heart attacks and strokes. Thrombosis is a consequence of platelet activation and aggregate formation within the circulation. Platelet ROS are mostly generated by reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. NOX2 is an isoform from NADPH oxidase expressed in platelets and an important regulator of platelet activation-associated thrombosis...
March 26, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29661709/are-cytokines-ready-for-prime-time-insights-from-markers-and-trials
#11
EDITORIAL
Andriana P Nikolova, Robin M Shaw
No abstract text is available yet for this article.
March 20, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29661711/diagnosing-spontaneous-coronary-artery-dissection-in-women-a-call-for-early-coronary-angiography
#12
EDITORIAL
Jane A Leopold
No abstract text is available yet for this article.
March 14, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29680719/non-pci-cabg-therapies-for-refractory-angina
#13
LETTER
Yoav Paz, Amihay Shinfeld
No abstract text is available yet for this article.
May 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29428161/potentialities-of-the-internal-mammary-arteries-and-refractory-angina
#14
LETTER
Marco Picichè
No abstract text is available yet for this article.
May 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29273184/editorial-commentary-treatment-of-refractory-angina-an-ongoing-challenge
#15
EDITORIAL
Udho Thadani
No abstract text is available yet for this article.
April 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29269286/editorial-commentary-targeting-tymp-for-cardiovascular-disease-how-far-are-we
#16
EDITORIAL
Matteo Vatta
No abstract text is available yet for this article.
April 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29108898/thymidine-phosphorylase-a-potential-new-target-for-treating-cardiovascular-disease
#17
REVIEW
Wei Li, Hong Yue
We recently found that thymidine phosphorylase (TYMP), also known as platelet-derived endothelial cell growth factor, plays an important role in platelet activation in vitro and thrombosis in vivo by participating in multiple signaling pathways. Platelets are a major source of TYMP. Since platelet-mediated clot formation is a key event in several fatal diseases, such as myocardial infarction, stroke and pulmonary embolism, understanding TYMP in depth may lead to uncovering novel mechanisms in the development of cardiovascular diseases...
April 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29735287/palliative-care-in-heart-failure-review
#18
REVIEW
Katie Wiskar, Mustafa Toma, Barret Rush
Palliative care (PC) is now recommended by all major cardiovascular societies for advanced heart failure (HF). PC is a philosophy of care that uses a holistic approach to address physical, psychosocial, and spiritual needs in patients with a terminal disease process. In HF, PC has been shown to improve symptoms and quality of life, facilitate advanced care planning, decrease hospital readmissions, and decrease hospital-associated healthcare costs. Although PC is still underutilized in HF, uptake is increasing...
February 21, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29661708/the-caveats-of-cardiac-imaging-in-ebstein-anomaly
#19
EDITORIAL
Matthias Greutmann, Emanuela R Valsangiacomo Buechel, Christine Attenhofer Jost
No abstract text is available yet for this article.
February 20, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29574046/editorial-commentary-preserving-myocardium-in-muscular-dystrophy-patients-using-ace-inhibition
#20
EDITORIAL
Michael D Taylor
No abstract text is available yet for this article.
February 20, 2018: Trends in Cardiovascular Medicine
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