journal
MENU ▼
Read by QxMD icon Read
search

Journal of Psychiatry & Neuroscience: JPN

journal
https://www.readbyqxmd.com/read/30226714/lifetime-major-depression-and-grey-matter-volume
#1
Marie-Laure Ancelin, Carrière Isabelle, Artero Sylvaine, Maller Jerome, Meslin Chantal, Ritchie Karen, Ryan Joanne, Chaudieu Isabelle
Background: There is evidence of structural brain alterations in major depressive disorder (MDD), but little is known about how these alterations might be affected by age at onset or genetic vulnerability. This study examines whether lifetime episodes of MDD are associated with specific alterations in grey-matter volume, and whether those alterations vary according to sex or serotonin transporter-linked promoter region (5-HTTLPR) genotype (LL, SL or SS). Methods: We used structural MRI to acquire anatomic scans from 610 community-dwelling participants...
September 18, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30106360/head-motion-the-dirty-little-secret-of-neuroimaging-in-psychiatry
#2
Carolina Makowski, Martin Lepage, Alan C Evans
Psychiatry is at a crossroads when choosing final samples for analysis of neuroimaging data. Many patient populations exhibit significantly increased motion in the scanner compared with healthy controls, suggesting that more patients would need to be excluded to obtain a clean sample. However, this need is often overshadowed by the extensive amount of time and effort required to recruit these valuable and uncommon samples. This commentary sheds light on the impact of motion on imaging studies, drawing examples from psychiatric patient samples to better understand how head motion can confound interpretation of clinically oriented questions...
August 14, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30106359/er%C3%AE-agonist-alters-rna-splicing-factor-expression-and-has-a-longer-window-of-antidepressant-effectiveness-than-estradiol-after-long-term-ovariectomy
#3
Xu Hou, Samuel O Adeosun, Xueying Zhao, Rosanne Hill, Baoying Zheng, Reveena Reddy, Xiao Su, Jeffrey Meyer, Thomas Mosley, Jun Ming Wang
BACKGROUND: Estrogen therapy (ET), an effective treatment for perimenopausal depression, often fails to ameliorate symptoms when initiated late after the onset of menopause. Our previous work has suggested that alternative splicing of RNA might mediate these differential effects of ET. METHODS: Female Sprague-Dawley rats were treated with estradiol (E2) or vehicle 6 days (early ET) or 180 days (late ET) after ovariectomy (OVX). We investigated the differential expression of RNA splicing factors and tryptophan hydroxylase 2 (TPH2) protein using a customized RT2 Profiler PCR Array, reverse-transcription polymerase chain reaction, immunoprecipitation and behaviour changes in clinically relevant early and late ET...
August 14, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30062996/a-review-of-functional-neurological-symptom-disorder-etiology-and-the-integrated-etiological-summary-model
#4
Aaron D Fobian, Lindsey Elliott
Functional neurological symptom disorder (FNSD) is characterized by neurological symptoms that are unexplained by other traditional neurological or medical conditions. Both physicians and patients have limited understanding of FNSD, which is often explained as a physical manifestation of psychological distress. Recently, diagnostic criteria have shifted from requiring a preceding stressor to relying on positive symptoms. Given this shift, we have provided a review of the etiology of FNSD. Predisposing factors include trauma or psychiatric symptoms, somatic symptoms, illness exposure, symptom monitoring and neurobiological factors...
July 31, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30062995/performance-monitoring-and-post-error-adjustments-in-adults-with-attention-deficit-hyperactivity-disorder-an-eeg-analysis
#5
Ann-Christine Ehlis, Saskia Deppermann, Andreas J Fallgatter
BACKGROUND: Recently, research into attention-deficit/hyperactivity disorder (ADHD) has focused increasingly on its neurobiological underpinnings, revealing (among other things) frontal lobe alterations. Specifically, action-monitoring deficits have been described, including impaired behavioural adjustments following errors. Our aim was to examine the neurophysiological background of post-error behavioural alterations in an adult ADHD sample for the first time, hypothesizing that people with ADHD would differ from controls in neurophysiological markers of cognitive preparation and stimulus processing, specifically following errors...
July 31, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29952748/resting-state-functional-connectivity-in-individuals-with-bipolar-disorder-during-clinical-remission-a-systematic-review
#6
Sabrina K Syan, Mara Smith, Benicio N Frey, Raheem Remtulla, Flavio Kapczinski, Geoffrey B C Hall, Luciano Minuzzi
BACKGROUND: Bipolar disorder is chronic and debilitating. Studies investigating resting-state functional connectivity in individuals with bipolar disorder may help to inform neurobiological models of illness. METHODS: We conducted a systematic review with the following goals: to summarize the literature on resting-state functional connectivity in bipolar disorder during clinical remission (euthymia) compared with healthy controls; to critically appraise the literature and research gaps; and to propose directions for future research...
June 28, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29952747/psychoradiological-patterns-of-small-world-properties-and-a-systematic-review-of-connectome-studies-of-patients-with-6-major-psychiatric-disorders
#7
Xueling Suo, Du Lei, Lei Li, Wenbin Li, Jing Dai, Song Wang, Manxi He, Hongyan Zhu, Graham J Kemp, Qiyong Gong
BACKGROUND: Brain connectome research based on graph theoretical analysis shows that small-world topological properties play an important role in the structural and functional alterations observed in patients with psychiatric disorders. However, the reported global topological alterations in small-world properties are controversial, are not consistently conceptualized according to agreed-upon criteria, and are not critically examined for consistent alterations in patients with each major psychiatric disorder...
June 28, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30125247/white-matter-network-alterations-in-patients-with-depersonalization-derealization-disorder
#8
Anika Sierk, Judith K Daniels, Antje Manthey, Jelmer G Kok, Alexander Leemans, Michael Gaebler, Jan-Peter Lamke, Johann Kruschwitz, Henrik Walter
BACKGROUND: Depersonalization/derealization disorder (DPD) is a chronic and distressing condition characterized by detachment from oneself and/or the external world. Neuroimaging studies have associated DPD with structural and functional alterations in a variety of distinct brain regions. Such local neuronal changes might be mediated by altered interregional white matter connections. However, to our knowledge, no research on network characteristics in this patient population exists to date...
August 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30125246/who-should-be-controls-in-studies-on-the-neurobiology-of-psychiatric-disorders
#9
Patricia Boksa, Ridha Joober
No abstract text is available yet for this article.
August 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30125245/neurocognitive-emotional-and-neuroendocrine-correlates-of-exposure-to-sexual-assault-in-women
#10
Yann Quidé, Helen Cléry, Frédéric Andersson, Céline Descriaud, Pauline Saint-Martin, Laurent Barantin, Valérie Gissot, Marie-Paule Carrey Le Bas, Sylvie Osterreicher, Diane Dufour-Rainfray, Bruno Brizard, Maja Ogielska, Wissam El-Hage
BACKGROUND: Survivors of sexual assault are vulnerable to long-term negative psychological and physical health outcomes, but few studies have investigated changes in cognition, emotional processing and brain function in the early stages after sexual assault. We used a multimodal approach to identify the cognitive and emotional correlates associated with sexual assault in women. METHODS: Twenty-seven female survivors of sexual assault were included within 4 weeks of the traumatic event, and they were compared with 20 age-matched controls...
August 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30125244/low-levels-of-muscarinic-m1-receptor-positive-neurons-in-cortical-layers-iii-and-v-in-brodmann-areas-9-and-17-from-individuals-with-schizophrenia
#11
Elizabeth Scarr, Shaun Hopper, Valentina Vos, Myoung Suk Seo, Ian Paul Everall, Timothy Douglas Aumann, Gursharan Chana, Brian Dean
BACKGROUND: Results of neuroimaging and postmortem studies suggest that people with schizophrenia may have lower levels of muscarinic M1 receptors (CHRM1) in the cortex, but not in the hippocampus or thalamus. Here, we use a novel immunohistochemical approach to better understand the likely cause of these low receptor levels. METHODS: We determined the distribution and number of CHRM1-positive (CHRM1+) neurons in the cortex, medial dorsal nucleus of the thalamus and regions of the hippocampus from controls ( n = 12, 12 and 5, respectively) and people with schizophrenia ( n = 24, 24 and 13, respectively)...
August 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30125243/resting-state-functional-connectivity-in-individuals-with-bipolar-disorder-during-clinical-remission-a-systematic-review
#12
Sabrina K Syan, Mara Smith, Benicio N Frey, Raheem Remtulla, Flavio Kapczinski, Geoffrey B C Hall, Luciano Minuzzi
BACKGROUND: Bipolar disorder is chronic and debilitating. Studies investigating resting-state functional connectivity in individuals with bipolar disorder may help to inform neurobiological models of illness. METHODS: We conducted a systematic review with the following goals: to summarize the literature on resting-state functional connectivity in bipolar disorder during clinical remission (euthymia) compared with healthy controls; to critically appraise the literature and research gaps; and to propose directions for future research...
August 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30125242/managing-disruptive-behaviour-in-autism-spectrum-disorder-with-guanfacine
#13
Lukas Propper
No abstract text is available yet for this article.
August 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/30125241/a-study-of-novel-bilateral-thermal-capsulotomy-with-focused-ultrasound-for-treatment-refractory-obsessive-compulsive-disorder-2-year-follow-up
#14
Se Joo Kim, Daeyoung Roh, Hyun Ho Jung, Won Seok Chang, Chan-Hyung Kim, Jin Woo Chang
BACKGROUND: Recently, a new thermal lesioning approach using magnetic resonance-guided focused ultrasound (MRgFUS) was introduced for the treatment of neurologic disorders. However, only 2 studies have used this approach for treatment-refractory obsessive-compulsive disorder (OCD), and follow-up was short-term. We investigated the efficacy and safety of bilateral thermal lesioning of the anterior limb of the internal capsule using MRgFUS in patients with treatment-refractory OCD and followed them for 2 years...
August 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29947611/social-anxiety-disorder-in-schizophrenia-a-neglected-yet-potentially-important-comorbidity
#15
Marc-André Roy, Marie-France Demers, Amélie M Achim
No abstract text is available yet for this article.
July 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29947610/the-maternal-brain-in-women-with-a-history-of-early-life-maltreatment-an-imagination-based-fmri-study-of-conflictual-versus-pleasant-interactions-with-children
#16
Corinne Neukel, Katja Bertsch, Anna Fuchs, Anna-Lena Zietlow, Corinna Reck, Eva Moehler, Romuald Brunner, Felix Bermpohl, Sabine C Herpertz
BACKGROUND: Early-life maltreatment has severe consequences for the affected individual, and it has an impact on the next generation. To improve understanding of the intergenerational effects of abuse, we investigated the consequences of early-life maltreatment on maternal sensitivity and associated brain mechanisms during mother-child interactions. METHODS: In total, 47 mothers (22 with a history of physical and/or sexual childhood abuse and 25 without, all without current mental disorders) took part in a standardized real-life interaction with their 7- to 11-year-old child (not abused) and a subsequent functional imaging script-driven imagery task...
July 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29947609/abnormal-dynamic-functional-connectivity-of-amygdalar-subregions-in-untreated-patients-with-first-episode-major-depressive-disorder
#17
Lihua Qiu, Mingrui Xia, Bochao Cheng, Lin Yuan, Weihong Kuang, Feng Bi, Hua Ai, Zhongwei Gu, Su Lui, Xiaoqi Huang, Yong He, Qiyong Gong
BACKGROUND: Accumulating evidence supports the concept of the amygdala as a complex of structurally and functionally heterogeneous nuclei rather than as a single homogeneous structure. However, changes in resting-state functional connectivity in amygdalar subregions have not been investigated in major depressive disorder (MDD). Here, we explored whether amygdalar subregions - including the laterobasal, centromedial (CM) and superficial (SF) areas - exhibited distinct disruption patterns for different dynamic functional connectivity (dFC) properties, and whether these different properties were correlated with clinical information in patients with MDD...
July 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29947608/correction-enhanced-corticobulbar-excitability-in-chronic-smokers-during-visual-exposure-to-cigarette-smoking-cues
#18
(no author information available yet)
No abstract text is available yet for this article.
July 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29947607/effects-of-extended-release-naltrexone-on-the-brain-response-to-drug-related-stimuli-in-patients-with-opioid-use-disorder
#19
Zhenhao Shi, An-Li Wang, Kanchana Jagannathan, Victoria P Fairchild, Charles P O'Brien, Anna Rose Childress, Daniel D Langleben
BACKGROUND: Heightened response to drug-related cues is a hallmark of addiction. Extended-release naltrexone (XR-NTX) is a US Food and Drug Administration-approved pharmacotherapy for relapse prevention in patients with opioid use disorder (OUD). In these patients, XR-NTX has been shown to reduce brain responses to opioid-related visual stimuli. To assess the biomarker potential of this phenomenon, it is necessary to determine whether this effect is limited to opioid-related stimuli and whether it is associated with key OUD symptoms...
July 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29947606/examining-cognition-across-the-bipolar-schizophrenia-diagnostic-spectrum
#20
Amy J Lynham, Leon Hubbard, Katherine E Tansey, Marian L Hamshere, Sophie E Legge, Michael J Owen, Ian R Jones, James T R Walters
BACKGROUND: Cognitive impairments are well-established features of schizophrenia, but there is ongoing debate about the nature and degree of cognitive impairment in patients with schizoaffective disorder and bipolar disorder. We hypothesized that there is a spectrum of increasing impairment from bipolar disorder to schizoaffective disorder bipolar type, to schizoaffective disorder depressive type and schizophrenia. METHODS: We compared performance on the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery between participants with schizophrenia ( n = 558), schizoaffective disorder depressive type ( n = 112), schizoaffective disorder type ( n = 76), bipolar disorder ( n = 78) and healthy participants ( n = 103) using analysis of covariance with post hoc comparisons...
July 2018: Journal of Psychiatry & Neuroscience: JPN
journal
journal
30743
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"