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Journal of Investigational Allergology & Clinical Immunology

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https://www.readbyqxmd.com/read/30574872/relationship-between-air-pollution-meteorological-factors-and-grass-pollen-counts-with-seasonal-allergic-rhinitis-in-madrid-1996-and-2009
#1
M Cabrera, B Garzón García, S Moreno Grau, J Subiza
BACKGROUND: The aim of this study is to assess the relationships of meteorological and pollutant variables on the symptoms of patients with seasonal allergic rhinitis due to sensitization to grass pollen during two different time periods in Madrid. METHODS: During the period March 23 to December 31 in 1996 and 2009, were carried out a daily count of grass pollen grains (Burkard spore trap) and rhinitis symptoms score in two groups of patients (n = 25 in 1996 and n = 23 in 2009) with a history of seasonal allergic rhinitis...
December 21, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30574871/vegf-2549-2567-del18-polymorphism-and-irreversible-bronchoconstriction-in-asthmatics
#2
K Gomulka, J Liebhart, E Jaskula, A Lange, W Medrala
BACKGROUND: While the importance of vascular endothelial growth factor (VEGF) for the pathogenesis of several diseases (e.g. neoplasms) has been proven, the corresponding data for asthma, especially those relating to the potential associations between VEGF genetic variants and airway remodeling are relatively scarce. Objective: This study was purposed to evaluate the possible connection between a genetic factor which is polymorphism del/ins in the VEGF-promoter region and airway remodelling potential in asthmatics with and without irreversible bronchoconstriction...
December 21, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30561365/early-life-origins-of-asthma-a-review-of-potential-effectors
#3
REVIEW
I Bobolea, E Arismendi, A Valero, A Agustí
There is currently growing evidence that events occurring early in life, both before and after birth, are significantly associated with the risk of asthma, COPD and low lung function later in life. In fact, from conception to death there are continuous, dynamic numbers of gene-environment interactions that determine two fundamental biologic processes, lung development and lung ageing. Over 130 birth cohorts have been initiated in the last 30 years. These birth cohorts have improved our understanding of asthma inception, progression and persistency...
December 18, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30561364/asthma-exacerbations-in-the-pediatric-emergency-department-at-a-tertiary-hospi-tal-relationship-with-environmental-factors
#4
M A Marques-Mejías, M Tomás-Pérez, I Hernández, I López, S Quirce
BACKGROUND: Children with asthma suffer from recurrent respiratory symptoms and exacerbations due to multiple environmental factors. The aim of this study is to describe the prevalence and triggers of asthma exacerbations and their management in cohort of pediatric patients attended in an emergency department (ED). METHODS: This was an observational, retrospective, single center study, conducted in the pediatric ED of the Hospital Universitario La Paz (Madrid, Spain) in 2015...
December 18, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30457106/immune-basis-of-food-allergic-reactions
#5
REVIEW
D Lozano-Ojalvo, C Berin, L Tordesillas
Food allergies are diseases where the normal tolerance response to oral antigens is altered. Recent advances have begun to uncover mechanisms that mediate sensitization to food allergens and maintenance of this disease. Production of alarmins by epithelial cells triggers a cascade that leads to allergen-specific IgE synthesis. A role of IL-9 in mast cell recruitment and amplification of allergic response has also been identified. In recent years, increasing evidence suggests that sensitization to food allergens can be developed by non-oral routes, in particular the skin, which led to the proposal of the 'dual exposure hypothesis'...
November 20, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30457105/impact-of-ehealth-in-allergic-diseases-and-allergic-patients
#6
REVIEW
A Alvarez-Perea, S Sánchez-García, R Muñoz Cano, D Antolín-Amérigo, O Tsilochristou, D R Stukus
The emergence of new technology grants allergists and patients the opportunity to compile data and receive feedback regarding key symptoms, risk behaviour and/or management. The term "eHealth" refers to a diverse group of tools that use computerized technologies to improve efficacy and efficiency of the health care industry. eHealth comprises a variety of technologies, such as the use of mobile devices (mHealth) in medical care, including electronic diaries, wearable sensors or adherence monitoring; health informatics (e...
November 20, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30422116/action-plan-to-reach-the-global-availability-of-adrenaline-auto-injectors
#7
REVIEW
L Kase Tanno, P Demoly
Adrenaline is the first-line treatment for anaphylaxis and, therefore, listed as an essential medication for the treatment of anaphylaxis by the World Health Organization (WHO). However, the availability of auto-injector (AAI) forms for use in the first-aid treatment is limited to only 32% of all 195-world countries, mostly high-income countries. The key issues leading to the lack of availability of AAIs include cost but also national regulations, lack of regional evidence about the value of epinephrine and the limited accurate data about the epidemiology of anaphylaxis...
November 13, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30418155/adjuvants-in-allergen-specific-immunotherapy-modulating-and-enhancing-the-immune-response
#8
REVIEW
J M Zubeldia, M Ferrer, I Dávila, J L Justicia
Allergen-specific immunotherapy (AIT) is the only treatment that may affect the natural course of allergic diseases such as allergic asthma, allergic rhinitis, and IgEmediated food allergy. Adjuvants are used to induce a quicker, more potent, and longer-lasting AIT immune response. Up to now, only four compounds are used as adjuvants in currently marketed AIT products: aluminum hydroxide, calcium phosphate, microcrystalline tyrosine (MCT), and monophosphoryl lipid A (MPL). The three first adjuvants are delivery systems with depot effect, although they also may have immunomodulatory properties...
November 12, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30411701/re-evolution-of-asthma-management-dilemmas-and-new-paradigms
#9
REVIEW
A Valero, J Olaguibel, J Delgado, V Plaza, F Álvarez, J Molina, E Mascarós, S Quirce
Asthma is one of the most common inflammatory diseases in the world, and the main treatment goal is to achieve the best level of control for each patient. Although every patient is different, there are several clinical practice guidelines that can help physicians to manage this respiratory condition. However, the recommendations made by the different guidelines are not always identical, and new data on different management strategies are being continuously released, which can mislead both patients and physicians...
November 9, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30411700/epidemiological-data-of-anaphylaxis-in-french-emergency-departments
#10
J Corriger, E Beaudouin, C Rothmann, E Penven, Q Haumonte, H Thomas, J Picaud, V M Nguyen-Grosjean, J Corriger-Ippolito, F Braun, M De Talancé, B Auburtin, P Atain-Kouadio, A Borsa-Dorion, D Baugnon, M De Carvalho, R Jaussaud, P L Nguyen-Thi, P E Bollaert, P Demoly, L Kase Tanno
BACKGROUND: Although anaphylaxis has been pointed as a high priority public health issue in the allergy world community, morbidity and mortality epidemiological data are still not optimal. This first multi-centric epidemiological study performed in 7 French emergency departments for one year intended to map the key issues to substantiate the need for changes and support ongoing national and international efforts for better diagnosis, management and prevention of anaphylaxis. METHODS: This is a descriptive study using data routinely reported to French institutional administrative databases reported from 7 French public health institutions of the Lorraine region from January to December 2015, based on International Classification of Diseases (ICD)-10 pre-selected anaphylaxis-related codes and clinically validated as anaphylaxis cases...
November 9, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530399/second-hypersensitivity-pneumonitis-in-the-same-patient-caused-by-chinchillas
#11
M Guion Dusserre, T Soumagne, G Reboux, J Maitre, J C Dalphin
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530398/incidence-of-anaphylaxis-recorded-during-1-year-by-the-municipal-emergency-service-of-madrid-samur-pc
#12
R Gómez-Soler, M L Caballero
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530397/successful-slow-desensitization-to-tocilizumab-in-a-15-year-old-patient
#13
M Cansever, N Şahin, I Dursun, C Geyik, R Düşünsel, F Bektaş Kut, F Tahan
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530396/moderate-asymptomatic-subacute-eosinophilia-secondary-to-simvastatin-therapy
#14
M D de Las Marinas Alvarez, V López Calatayud, B Solaz Garrido, M Catalá Bauset, M Montesinos Carbonell, P Albert Sánchez
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530395/doxylamine-allergy-in-a-pregnant-woman-suitability-of-the-basophil-activation-test
#15
M J Rial, M Fernández-Nieto, J M Rodrigo-Muñoz, B Sastre, J Sastre, V Del Pozo
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530394/safety-of-an-ultrarush-4-hours-subcutaneous-immunotherapy-schedule-with-cat-and-dog-extracts-using-an-infusion-pump
#16
S Uriarte, J Sastre
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530393/peripheral-eosinophil-counts-correlate-with-nasal-eosinophil-counts-in-patients-with-rhinitis
#17
G Ciprandi, A Varricchio, G Tajana, I La Mantia, C Tommasino
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530392/severe-anaphylaxis-with-cardiac-arrest-caused-by-prick-test-with-cefuroxime
#18
R A Fernandes, F S Regateiro, J Pita, C Ribeiro, I Carrapatoso, A Todo-Bom, E Faria
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530391/hypersensitivity-to-imatinib-successful-desensitization-in-a-skin-test-positive-patient
#19
E Penza, D Bignardi, M Bergamaschi, S Beltramini, F Mina, K Lappas, P Minale
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/30530390/ctla-4-expression-in-cd4-t-cells-from-patients-with-lrba-deficiency-and-common-variable-immunodeficiency-with-no-known-monogenic-disease
#20
G Azizi, M Jamee, R Yazdani, Y Bagheri, F Fayyaz, F Jadidi-Niaragh, H Abolhassani, A Aghamohammadi
No abstract text is available yet for this article.
December 2018: Journal of Investigational Allergology & Clinical Immunology
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