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Journal of Investigational Allergology & Clinical Immunology

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https://www.readbyqxmd.com/read/29761786/association-of-a-four-locus-gene-model-including-il13-il4-fcer1b-and-adrb2-with-the-asthma-predictive-index-and-atopy-in-chinese-han-children
#1
S Bai, L Hua, X Wang, Q Liu, Y Bao
BACKGROUND AND OBJECTIVE: Asthma is a complex and heterogeneous disease. We found that gene-gene interactions among IL13 rs20541, IL4 rs2243250, ADRB2 rs1042713, and FCER1B rs569108 in asthmatic children of Chinese Han nationality. This four-locus set constituted an optimal statistical interaction model. Objective: This study examined associations of the four-gene model consisting of IL13, IL4, FCER1B, and ADRB2 with the Asthma Predictive Index (API) and atopy in Chinese Han children...
May 11, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29717706/impact-of-specific-training-in-anaphylaxis-of-the-triage-nursing-staff-in-a-tertiary-hospital-s-paediatric-emergency-department
#2
E Arroabarren, J Alvarez-García, M Anda, M de Prada, C Ponce, M J Alvarez-Puebla
BACKGROUND: After a diagnosis of anaphylaxis, patients receive action management plans to prevent and treat new episodes, including attending the Emergency Departments (ED) for control or further treatment. In a previous study, we observed that more than half of the children with anaphylaxis were incorrectly prioritized in our Paediatrics Emergency Unit (PEU), delaying their treatment. In conjunction with our PEU staff we designed a basic educational intervention (BEI) to try to solve this problem...
May 2, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29688172/comparative-effect-of-beclomethasone-dipropionate-and-cetirizine-on-acoustic-rhinometry-parameters-in-children-with-perennial-allergic-rhinitis-a-randomized-controlled-trial
#3
V Malizia, S Fasola, G Ferrante, G Cilluffo, R Gagliardo, M Landi, L Montalbano, D Marchese, S La Grutta
BACKGROUND AND OBJECTIVE: The effect of intranasal corticosteroids and oral antihistamines on acoustic rhinometry parameters was not directly compared in previous studies. Objectives: The primary aim was to compare the effect of 21-day treatment with nasal beclomethasone dipropionate (nBDP) versus cetirizine (CTZ) on nasal patency measured by acoustic rhinometry in children with PAR. Comparing their effect on nasal cytology, symptom severity, sleep quality and quality of life was the secondary aim...
April 24, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29667580/severe-asthma-phenotypes-classified-by-site-of-airway-involvement-and-remodeling-via-chest-ct-scan
#4
S Kim, K Nam Jin, S H Cho, C Hyun Lee, H R Kang
BACKGROUND AND OBJECTIVE: This study aimed to establish a system that can classify severe asthma on the basis of airway remodeling patterns visualized by computed tomography (CT) images and to evaluate the clinical characteristics of individual image-based subtypes. METHODS: Chest CT images of severe asthma patients were retrospectively evaluated to classify phenotypes by site of airway involvement and remodeling. The association between radiologic subtypes and clinical characteristics was assessed...
April 18, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29589586/tryptase-increase-on-the-first-day-of-hymenoptera-venom-immunotherapy-might-be-a-predictor-of-future-systemic-reactions-during-treatment
#5
A Vega-Castro, A Alonso-Llamazares, R Cárdenas, J M Beitia, B Mateo, I Alvarez-Twose, C Blanco
BACKGROUND AND OBJECTIVE: Serum tryptase (ST) decreases in long-term venom immunotherapy (VIT). A circadian tryptase variation with a small decrease has been found after sting challenge. Both findings have been related to successful VIT. Objective: To assess whether variation (increase or decrease) in ST on the first day of VIT is associated with the likehood of future systemic adverse reactions (SAR) during treatment. METHODS: We prospectively studied patients who underwent cluster VIT and continued it for at least 6 months...
March 28, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29528033/incidence-of-childhood-eosinophilic-esophagitis-in-central-brazil-how-many-are-we-missing
#6
L O Gonçalves, M M Lopes, E R Rezende, G Rs Segundo
BACKGROUND: Few studies have assessed the incidence of eosinophilic esophagitis (EoE) in childhood. The study aim is to determine the incidence of EoE in pediatric patients submitted to upper gastrointestinal endoscopy (UGE), with analysis of epidemiological data regarding sex, age, symptomatology, the frequency of atopy and endoscopic and histological findings. METHODS: A retrospective, observational and analytical study performed with an evaluation of medical records of patients aged 0 to 14 years who underwent to upper gastrointestinal endoscopy in a tertiary hospital from January 2004 to January 2014...
March 12, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29688173/safety-and-quality-recommendations-in-allergy-medicine-spanish-acronym-rescal
#7
REVIEW
C Vidal, D Antolín, M Reaño, A Valero, J Sastre
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29661744/allergy-to-limanda-aspera-yellowfin-sole-report-of-a-case-of-food-allergy-in-a-child
#8
M Viñas, F Pineda, A Izquierdo-Domínguez, M Castillo, M J Castillo, N Hernández, B Delavalle, J Barrena, M Ibero
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29661743/anaphylaxis-to-etoricoxib
#9
M Couto, R López-Salgueiro, Â Gaspar
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29661742/overlap-between-dress-syndrome-and-exanthema-induced-by-sulfadiazine-in-a-patient-treated-with-sulfamethoxazole-utility-of-the-lymphocyte-transformation-test-for-identification-of-the-culprit-drug
#10
O P Monge-Ortega, R Cabañas, A Fiandor, J Domínguez-Ortega, M González-Muñoz, S Quirce, M Lluch-Bernal, T Bellón
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29661741/recall-urticaria-aspirin-also-induces-it
#11
S Cimbollek, M R Ávila-Castellano, M Labella, K Baynova, T Aramburu, J Quiralte
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29661740/tolerability-and-immunological-effect-of-short-up-dosing-immunotherapy-with-2-standardized-native-allergen-extracts-derived-from-the-pollen-of-salsola-kali-and-cupressus-arizonica
#12
P González Delgado, E Ibáñez Echevarría, M Antón Gironés, M Rodríguez Mosquera, M D Alonso Díaz de Durana, P Prieto Montaño, A Marín de Pablo, M Fernández-Rivas
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29661739/eosinophilic-fasciitis-in-association-with-hypereosinophilic-syndrome-in-an-hiv-infected-patient-with-severe-multiorgan-involvement
#13
N A Richarz, A Olivé Marques, J M Llibre, B Xicoy Cirici, N Zhu, M Gomez Plaza, I Bielsa-Marsol
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29465401/real-life-evaluation-of-the-degree-of-compliance-to-recommendations-of-anaphylaxis-guidelines-in-an-emergency-department-of-a-tertiary-hospital
#14
L V Ponce Guevara, E Laffond Yges, M T Gracia Bara, E Moreno Rodilla, F J Muñoz Bellido, M Lázaro Sastre, E M Macías Iglesias, S de Arriba Méndez, M V Campanón Toro, I Dávila Gónzalez
BACKGROUND AND OBJECTIVE: To date, few studies have evaluated the degree of compliance with recommendations of anaphylaxis guidelines in emergency departments (EDs). Objective: The objective of this study was to evaluate adherence to anaphylaxis guidelines recommendations in an ED of a tertiary hospital. METHODS: Medical records of patients that were assisted in the ED of the University Hospital of Salamanca (Spain) were reviewed. Those patients fulfilling anaphylaxis criteria proposed by the NIAID/FAAN were selected...
February 21, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29411703/social-media-as-a-tool-for-the-management-of-food-allergy-in-children
#15
A Alvarez-Perea, P Cabrera-Freitag, V Fuentes-Aparicio, S Infante, L Zapatero, J M Zubeldia
BACKGROUND: Food allergy heavily impairs quality of life. Avoiding the offending food requires extensive patient education. Social media have been proven a useful source of information for other chronic conditions. Our aim was to describe how pediatric patients with food allergy and their families are using social media. METHODS: We performed a cross-sectional study in the Pediatric Allergy Unit of a third-level hospital. Patients with food allergy were surveyed about their disease and the use of social media...
February 7, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29411702/practical-guidelines-for-perioperative-hypersensitivity-reactions
#16
REVIEW
J J Laguna, J Archilla, I Doña, M Corominas, G Gastaminza, C Mayorga, P Berjes-Gimeno, P Tornero, S Martin, A Planas, E Moreno, M J Torres
Perioperative hypersensitivity reactions constitute a first-line problem for anesthesiologists and allergists, so it is advisable that hospitals have a consensus protocol for the diagnosis and management of these reactions. However, this kind of protocols is not present in many hospitals, leading to problems in treatment, the communication of incidents and subsequent etiological diagnosis. In this document we present a systematic review of the available scientific evidence and provide general guidelines for the management of acute episodes and for referral of patients with perioperative hypersensitivity reactions to Allergy Units...
February 7, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29345621/the-circulating-t-helper-subsets-and-regulatory-t-cells-in-patients-with-common-variable-immunodeficiency-with-no-known-monogenic-disease
#17
G Azizi, A Mirshafiey, H Abolhassani, R Yazdani, F J Ansariha, M Shaghaghi, S S Mortazavi-Jahromi, F Noorbakhsh, N Rezaei, A Aghamohammadi
BACKGROUND: Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency (PID), characterized by heterogeneous clinical manifestations and defects in B- and T- cells. In the present study, we investigated the T helper (Th) cell subsets and regulatory T (Treg) cells, and their related cytokines and transcription factors in the CVID patients with no definite genetic diagnosis. METHODS: The study population comprised 13 CVID patients and 13 healthy controls (HC)...
January 18, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29345236/glcci1-polymorphism-rs37973-and-asthma-treatment-response-to-inhaled-corticosteroids
#18
M Rijavec, M Žavbi, A Lopert, M Fležar, P Korošec
BACKGROUND: Asthma treatment response is highly variable and pharmacogenetic markers that predict treatment response would be one step closer to personalized treatment. GWAS studies have shown that polymorphisms GLCCI1 could be associated with asthma treatment response to inhaled corticosteroids (ICS). MATERIAL AND METHODS: We genotyped rs37973 of GLCCI1 in 208 adult asthma patients treated with ICS. Change in % predicted FEV1 was analysed after short-term (3 months) and after long-term (at least 3 years) treatment...
January 17, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29345235/news-on-climate-change-air-pollution-and-allergic-trigger-factors-of-asthma
#19
REVIEW
M D'Amato, L Cecchi, I Annesi-Maesano, G D'Amato
The rising frequency of obstructive respiratory diseases,in particular allergic asthma, observed over the last years, can be partially explained by changes occurring in the environment, with increasing presence in atmosphere of chemical (particulate matter and gaseous components such as nitrogen dioxide and ozone) and biologic (aeroallergens) trigger factors. Aeroallergens are able to stimulate, in allergic subjects, the airways' sensitization, inducing symptoms of bronchial asthma. Over the last 50 years, global earth's temperature has markedly risen likely because of growing emission of anthropogenic greenhouse gas concentrations...
January 17, 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29297467/expansion-of-a-cd26-low-effector-th-subset-and-reduction-of-circulating-levels-of-scd26-in-stable-allergic-asthma-in-adults
#20
J J Nieto-Fontarigo, F J González-Barcala, M E San-José, M J Cruz, T Linares, M T Soto-Mera, L Valdés, M A García-González, L J Andrade-Bulos, P Arias, M Nogueira, F J Salgado
BACKGROUND AND OBJECTIVE: Asthma pathogenesis is dependent on the balance between regulatory and effector T cells, which display differential expression of CD25 and CD26. Therefore, alteration of circulating levels of sCD25 and sCD26 during allergic asthma could be conditioned by leukocyte phenotype changes. Objectives: To analyse CD25 and CD26 expression on T lymphocytes and their soluble derivatives (sCD25, sCD26) during stable phases of moderate-severe allergic asthma. METHODS: Cross-sectional study with two adult cohorts of allergic asthmatics...
January 3, 2018: Journal of Investigational Allergology & Clinical Immunology
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