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Journal of Investigational Allergology & Clinical Immunology

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https://www.readbyqxmd.com/read/27834188/quality-indicators-of-asthma-care-derived-from-the-spanish-guideline-for-asthma-management-gema-4-0-a-multidisciplinary-team-report
#1
S Quirce, J Delgado, J L Entrenas, M Grande, C Llorente, A López Viña, E Martínez Moragón, E Mascarós, J Molina, J M Olaguibel, L A Pérez de Llano, M Perpiñá Tordera, J A Quintano, M Rodríguez, M Román-Rodriguez, J Sastre, J A Trigueros, A L Valero, A C Zoni, V Plaza
No abstract text is available yet for this article.
November 11, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27758759/nasal-ketorolac-challenge-using-an-acoustic-rhinomether-in-patients-with-aspirin-exacerbated-respiratory-disease
#2
J Quiralte-Castillo, M Del Robledo Ávila-Castellano, S Cimbollek, P Benaixa, S Leguisamo, K Baynova, M Labella, J Quiralte
BACKGROUND: Safer and less time consuming alternatives to single-blind placebo-controlled oral challenge (SBPCOC) in order to diagnose aspirin-exacerbated respiratory disease (AERD) have been searched for. Nasal challenges with different non-steroidal anti-inflammatory drugs and assessment methods have been developed. OBJECTIVE: Our objective was to evaluate the utility and safety of nasal ketorolac challenge (NKC) using an acoustic rhinomether in patients with suspected AERD Methods: Thirty-six patients with suspected AERD were included in the study...
October 19, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27758758/effects-of-rupatadine-on-platelet-activating-factor-paf-induced-human-mast-cell-degranulation-compared-with-desloratadine-and-levocetirizine-the-maspaf-study
#3
R Muñoz-Cano, E Ainsua-Enrich, I Torres-Atencio, M Martin, J Sánchez-Lopez, J Bartra, C Picado, J Mullol, A Valero
RATIONALE: Platelet activating factor (PAF) is a lipid mediator involved in the pathophysiology of several allergic diseases, such as the amplification of mast cell (MC) activation in anaphylaxis. Rupatadine is an antihistamine with demonstrated anti-PAF effect but its capacity to inhibit PAF-induced MC degranulation has not been fully evaluated. OBJECTIVE: To investigate the ability of rupatadine to inhibit PAF-induced MC degranulation compared with desloratadine and levocetirizine, to confirm dual rupatadine anti-H1 and anti-PAF activities...
October 19, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27727140/eosinophilic-esophagitis-demographic-clinical-endoscopic-histological-and-allergological-characteristics-in-children-and-teenagers-in-a-region-of-central-spain
#4
E Gómez Torrijos, P Sánchez Miranda, P Donado Palencia, A Castro Jimenez, J Rodriguez Sánchez, Y Mendez Díaz, L Moreno Lozano, R García Rodríguez
BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic inflammatory emerging disease of the oesophagus with immunoallergic aetiology. Until now, few studies about this disease in children and adolescents have been published Objectives: To study the demographic, clinical, serologic, endoscopic-histological and allergologic characteristics of the patients and their atopic and digestive comorbidities. METHODOLOGY: It is an prospective observacional study in children and adolescents (<16 years) assessed in a multidisciplinary specialized eosinpophilic esopahgitis unit in a tertiary referral centre in the central region of Spain carried out between 2011-2015...
October 10, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27609533/lettuce-allergy-is-a-lipid-transfer-syndrome-related-food-allergy-with-high-risk-of-severe-reactions
#5
E Muñoz-García, O Luengo-Sánchez, N Moreno-Pérez, J Cuesta-Herranz, C Pastor-Vargas, V Cardona
BACKGROUND AND OBJESTIVES: Background: Lipid transfer protein (LTP) sensitization is the most common cause of food allergy in the Mediterranean area, with peach allergy acting as the primary sensitizer in most cases. Lettuce allergy has been reported as a common offending food in patients affected of LTP syndrome. Objectives: The aim of the study was to investigate the frequency of LTP syndrome in a sample of lettuce allergic patients and assess its clinical expression. METHODS: We determined sIgE to Pru p 3 and lettuce in a sample of 30 patients with a diagnosis of lettuce allergy...
September 9, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27564130/cost-effectiveness-and-budget-impact-of-routine-use-of-fractional-exhaled-nitric-oxide-monitoring-for-the-management-of-adult-asthma-patients-in-spain
#6
L Sabatelli, U Seppälä, J Sastre, G Crater
OBJECTIVES: Fractional exhaled nitric oxide (FeNO) is a marker for Type-2 airway inflammation. The objective of this study was to evaluate cost-effectiveness and budget impact of FeNO monitoring for management of adult asthma in Spain. METHODS: Cost-effectiveness model analysis was used to evaluate the economic outcomes when asthma management was assisted with FeNO monitoring. Over a one-year period, the model estimated the incremental cost per quality-adjusted life year (QALY) and incremental number of exacerbations avoided when FeNO monitoring was added to standard guideline-driven asthma care and compared to standard care alone...
August 26, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27383031/regulatory-t-and-b-cells-in-asthmatic-women-variations-from-pregnancy-to-postpartum-treg-and-breg-pregnancy-to-postpartum
#7
C Martins, J Lima, G Nunes, L M Borrego
BACKGROUND: Allergic asthma and rhinitis are common in pregnancy. The immune mechanisms underlying the effects of pregnancy in asthma and vice-versa are not completely understood. OBJECTIVES: This work aimed to study the evolution of regulatory T and B cells in asthmatic pregnant women, from late pregnancy till postpartum. METHODS: Four groups of women were enrolled for this study: third trimester pregnant women, asthmatic (n=24) and healthy (n=43), and non-pregnant women, asthmatic (n=33) and healthy (n=35)...
June 14, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27382966/validation-of-recipes-for-double-blind-placebo-controlled-challenges-with-milk-egg-white-and-hazelnut
#8
E González-Mancebo, M D Alonso Díaz de Durana, Y García Estringana, A Meléndez Baltanás, M Rodriguez-Alvarez, B de la Hoz Caballer, N Del Prado, M Fernández-Rivas
BACKGROUND: The double-blind, placebo-controlled food challenge (DBPCFC) is considered the definitive diagnostic test for food allergy. Despite this, there is a lack of validated of recipes for masking the foods, they are not standardised and differ among centres. Sensory tests are necessary to validate the recipes used for DBPCFC. METHODS: Three recipes for use in DBPCFC with milk, egg white and hazelnut were developed and the triangle test was used to validate them in a 2-phase study in which 197 volunteers participated...
May 24, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27385381/immediate-reactions-to-more-than-one-nsaid-must-not-be-considered-as-cross-hypersensitivity-unless-asa-tolerance-is-verified
#9
D Pérez-Alzate, J A Cornejo-García, N Pérez-Sánchez, I Andreu, A García-Moral, J A Agúndez, J Bartra, I Doña, M J Torres, M Blanca, N Blanca-López, G Canto
BACKGROUND: Subjects who develop drug hypersensitivity reactions (DHRs) to chemically unrelated non-steroidal anti-inflammatory drugs (NSAIDs) are considered cross-hypersensitive. The hallmark for this category is that they present a reaction after ASA intake or challenge. Whether patients react to two or more NSAIDs with tolerance to ASA remains to be studied (selective reactions, SRs). OBJECTIVE: To identify patients with SRs to two or more NSAIDs including strong COX-1 inhibitors...
May 18, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27374925/analysis-of-the-safety-and-tolerance-of-three-buildup-protocols-of-insect-venom-immunotherapy-frequently-used-in-spain
#10
D Gutiérrez Fernández, A Moreno-Ancillo, S Fernández Meléndez, C Domínguez-Noche, P Gálvez Ruiz, T Alfaya Arias
INTRODUCTION: Hymenoptera venom immunotherapy (VIT) is an effective treatment but not one devoid of risk as both local and systemic adverse reactions may occur especially in the initial stages of treatment. We compared the tolerance to three buildup protocols of VIT and analyzed risk factors associated with adverse reactions occurring in this phase. METHODS: We enrolled 165 patients divided into three groups based on the buildup protocol used (3, 4, 9 weeks). Severity of systemic reactions was evaluated according to World Allergy Organization model...
April 19, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27374617/polcalcins-from-different-pollen-sources-show-different-ige-reactivity
#11
R Asero, G Mistrello, S Amato
BACKGROUND: Polcalcins are highly cross-reacting pollen panallergens able to sensitize less than 10% of allergic patients. All pollen species are considered able to sensitize patients to this panallergen. OBJECTIVE: We aimed to assess the presence of polcalcin in different pollen extracts for allergen immunotherapy. METHODS: Sera from polcalcin reactors as well as rPhl p7 and rBet v 4 were checked in an ELISA inhibition assay, using the recombinant polcalcin as substrate and freshly prepared pollen extracts as inhibitors...
April 11, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27374382/ige-api-m4-is-useful-to-identify-a-particular-phenotype-of-allergy-to-bee-venom
#12
B Ruiz, P Serrano, C Moreno
BACKGROUND: Different clinical behaviours have been identified in patients allergic to bee venom. Compound resolved diagnosis could be appropriated to looking for these differences. Objective: to analyse if sIgE-Api m 4 is able to identify a particular kind of allergy to bee venom, and to describe the response to bee venom immunotherapy (bVIT) of patients. METHODS: Prospective study including 31 patients allergic to bee venom, who were allocated depending on sIgE-Api m4<0...
April 11, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27365254/profiles-of-birch-sensitization-bet-v-1-bet-v-2-bet-v-4-and-oral-allergy-syndrome-across-italy
#13
G Ciprandi, P Comite, M Mussap, M De Amici, S Quaglini, F Barocci, G Marseglia, E Scala
BACKGROUND: Birch allergy (BA) is a common pollinosis. Bet v 1, Bet v 2, and Bet v 4 are birch allergen molecules. Oral allergic syndrome (OAS) is frequently associated with BA. Previously, it has been reported that there is a gradient of birch allergen sensitization profile across Europe. Thus, this study aimed to investigate the birch sensitization profile, including OAS, across Italy. METHODS: This retrospective study considered a series of 854 patients (391 males, mean age 35...
April 11, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27763871/induction-of-tolerance-by-oral-immunotherapy-in-patients-with-cow-s-milk-allergy
#14
M Ebrahimi, M Gharagozlou, A Khalili, K Magaji Hamid, G Azizi, M Movahedi
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27763870/evaluation-of-tolerance-in-patients-with-type-1-hypersensitivity-reaction-to-wheat-after-oral-immunotherapy
#15
A Khalili, A Khayatzadeh, M Ebrahimi, H Rafiemanesh, G Azizi, M Movahedi
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27763869/therapeutic-potential-of-zoledronate-activated-autologous-%C3%AE-%C3%AE-t-cells-in-atopic-dermatitis
#16
T Kamigaki, K Naitoh, S Goto
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27763868/kounis-syndrome-after-levofloxacin-intake-a-clinical-report-and-cross-reactivity-study
#17
I García Núñez, M A Algaba Mármol, M J Barasona Villarejo, M Suárez Vergara, F Espínola González, E Reina Ariza
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27763867/resolution-of-common-variable-immunodeficiency-after-hiv-infection
#18
V Balugo-López, E Hernández García de la Barrera, J Sastre
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27763866/vitiligo-induced-by-specific-immunotherapy-with-grass-pollen-the-koebner-phenomenon
#19
B Rodríguez-Jiménez, E Muñoz-García, S Veza Perdomo, C González Herrada, C Kindelán-Recarte, J Domínguez-Ortega
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27763865/cross-reactivity-in-aed-induced-severe-cutaneous-adverse-reaction-a-case-report
#20
A Hp Khor, K S Lim, C T Tan, Z Kwan, C C Ng
No abstract text is available yet for this article.
2016: Journal of Investigational Allergology & Clinical Immunology
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