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Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society

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https://www.readbyqxmd.com/read/28213658/postural-tachycardia-syndrome-and-suicide-what-we-don-t-know
#1
EDITORIAL
Vidya Raj, Satish R Raj
No abstract text is available yet for this article.
February 18, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28205011/neural-control-of-blood-pressure-in-women-differences-according-to-age
#2
Ana B Peinado, Ronee E Harvey, Emma C Hart, Nisha Charkoudian, Timothy B Curry, Wayne T Nicholson, B Gunnar Wallin, Michael J Joyner, Jill N Barnes
PURPOSE: The blood pressure "error signal" represents the difference between an individual's mean diastolic blood pressure and the diastolic blood pressure at which 50% of cardiac cycles are associated with a muscle sympathetic nerve activity burst (the "T50"). In this study we evaluated whether T50 and the error signal related to the extent of change in blood pressure during autonomic blockade in young and older women, to study potential differences in sympathetic neural mechanisms regulating blood pressure before and after menopause...
February 16, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28190177/cardiovascular-testing-in-patients-with-postural-tachycardia-syndrome-and-ehlers-danlos-type-iii-authors-response
#3
LETTER
Jem L Cheng, Jason S Au, Juan C Guzman, Carlos A Morillo, Maureen J MacDonald
No abstract text is available yet for this article.
February 11, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28190176/onset-of-bladder-and-motor-symptoms-in-multiple-system-atrophy-differences-according-to-phenotype
#4
Jinhua Zheng, Xinglong Yang, Yalan Chen, Quanzhen Zhao, Sijia Tian, Hongyan Huang, Yanming Xu
PURPOSE: To compare the order of presentation of bladder and motor symptoms between multiple system atrophy phenotypes. METHODS: Medical records were retrospectively reviewed in 144 patients. RESULTS: Bladder symptoms occurred either before or within 12 months after onset of motor symptoms in significantly more patients with the cerebellar phenotype than the parkinsonian phenotype (80 vs. 53%, p = 0.003); similar results were observed for urinary incontinence (79 vs...
February 11, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28188385/pure-autonomic-failure-without-synucleinopathy
#5
Risa Isonaka, Courtney Holmes, Glen A Cook, Patti Sullivan, Yehonatan Sharabi, David S Goldstein
Pure autonomic failure is a rare form of chronic autonomic failure manifesting with neurogenic orthostatic hypotension and evidence of sympathetic noradrenergic denervation unaccompanied by signs of central neurodegeneration. It has been proposed that pure autonomic failure is a Lewy body disease characterized by intra-neuronal deposition of the protein alpha-synuclein in Lewy bodies and neurites. A middle-aged man with previously diagnosed pure autonomic failure experienced a sudden, fatal cardiac arrest. He was autopsied, and tissues were harvested for neurochemical and immunofluorescence studies...
February 10, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28188384/the-spoon-test-a-valid-and-reliable-bedside-test-to-assess-sudomotor-function
#6
Ramesh K Khurana, Colin Russell
OBJECTIVE: To establish the validity of bedside sudomotor tests in a controlled prospective study. METHODS: Five different tests were used to assess presence of sweating at seven bilaterally symmetrical body loci, namely, examination with the unaided eye, visualization with light reflection, magnification with an ophthalmoscope, palpation of skin for slickness, and gliding the back of a spoon over the skin to detect friction. Sensitivity and specificity of these bedside tests were compared with the thermoregulatory sweat test in 130 subjects with generalized body sweating and 16 patients with complete anhidrosis...
February 10, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28168561/health-related-quality-of-life-and-suicide-risk-in-postural-tachycardia-syndrome
#7
Cathy L Pederson, Jill Blettner Brook
PURPOSE: Postural tachycardia syndrome (POTS) is a disorder featured by orthostatic intolerance. The purpose of this study was to investigate the severity of quality of life issues in POTS patients. METHODS: Online surveys for health related quality of life, sleep quality, fatigue, pain, and suicidal ideation were completed by 624 POTS patients and 139 controls. RESULTS: People with POTS have significantly more days of poor physical health (p < 0...
February 6, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28154947/autonomic-cardiovascular-modulation-in-masters-and-young-cyclists-following-high-intensity-interval-training
#8
Nattai R Borges, Peter R Reaburn, Thomas M Doering, Christos K Argus, Matthew W Driller
PURPOSE: This study aimed at examining the autonomic cardiovascular modulation in well-trained masters and young cyclists following high-intensity interval training (HIT). METHODS: Nine masters (age 55.6 ± 5.0 years) and eight young cyclists (age 25.9 ± 3.0 years) completed a HIT protocol of 6 x 30 sec at 175% of peak power output, with 4.5-min' rest between efforts. Immediately following HIT, heart rate and R-R intervals were monitored for 30-min during passive supine recovery...
February 2, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28108826/the-sacral-parasympathetic-system-is-actually-sympathetic-and-other-updates-on-recent-autonomic-research
#9
EDITORIAL
Mitchell G Miglis, Srikanth Muppidi
No abstract text is available yet for this article.
January 20, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28101744/cardiovascular-testing-in-patients-with-postural-orthostatic-tachycardia-syndrome-and-ehlers-danlos-syndrome-type-iii
#10
LETTER
Svetlana Blitshteyn, David Fries
No abstract text is available yet for this article.
January 18, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28091831/acknowledgement-to-reviewers
#11
(no author information available yet)
No abstract text is available yet for this article.
January 16, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28083798/reliability-of-orthostatic-beat-to-beat-blood-pressure-tests-implications-for-population-and-clinical-studies
#12
C Finucane, G M Savva, R A Kenny
OBJECTIVE: To assess the test-retest reliability of orthostatic beat-to-beat blood pressure responses to active standing and related clinical definitions of orthostatic hypotension. METHODS: A random sample of community-dwelling older adults from the pan-European Survey of Health, Ageing and Retirement in Europe, Ireland underwent a health assessment that mimicked that of the Irish Longitudinal Study on Ageing. An active stand test was performed using continuous blood pressure measurements...
January 12, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28005189/cardiovascular-profile-in-postural-orthostatic-tachycardia-syndrome-and-ehlers-danlos-syndrome-type-iii
#13
LETTER
Jem L Cheng, Jason S Au, Juan C Guzman, Carlos A Morillo, Maureen J MacDonald
The cardiovascular profile of postural orthostatic tachycardia syndrome + Ehlers-Danlos syndrome hypermobility type (POTS + EDSIII) has not been described, despite suggestions that it plays a role in orthostatic intolerance. We studied nine individuals diagnosed with POTS + EDSIII and found that the arterial stiffness and cardiac profiles of patients with POTS + EDSIII were comparable to those of age- and sex-matched controls, suggesting an alternate explanation for orthostatic intolerance.
December 22, 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27942951/effects-of-face-cooling-on-pulse-waveform-and-sympathetic-activity-in-hypertensive-subjects
#14
Eliza Prodel, Thales C Barbosa, Daniel E Mansur, Antonio Claudio L Nóbrega, Lauro C Vianna
Adverse cardiovascular events occur more frequently during cold weather. To test the hypothesis that cold exposure would lead to increased sympathetic activity and impaired hemodynamic control, we measured muscle sympathetic nerve activity and hemodynamic parameters in nine men with hypertension before and during trigeminal stimulation and facial cooling. The procedure increased blood pressure (p < 0.01), aortic hemodynamic parameters (p < 0.01), and muscle sympathetic nerve activity (p < 0.05)...
December 9, 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27913968/post-ganglionic-autonomic-neuropathy-associated-with-anti-glutamic-acid-decarboxylase-antibodies
#15
E Fileccia, R Rinaldi, R Liguori, A Incensi, R D'Angelo, M P Giannoccaro, V Donadio
PURPOSE: Antibodies to glutamic acid decarboxylase (GAD-Abs) have been associated with several conditions, rarely involving the autonomic nervous system. Here, we describe two patients complaining of autonomic symptoms in whom a post-ganglionic autonomic neuropathy has been demonstrated in association with significantly elevated serum and CSF GAD-Abs levels. METHODS: Patients underwent nerve conduction studies, sympathetic skin response testing, evaluation of autonomic control of the cardiovascular system and skin biopsy...
December 2, 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28124174/the-clinical-autonomic-research-journal-2017-and-onward
#16
EDITORIAL
Horacio Kaufmann, Jens Jordan
No abstract text is available yet for this article.
February 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27838779/acute-cyclooxygenase-inhibition-and-baroreflex-sensitivity-in-lean-and-obese-adults
#17
Abdulrahman A Al-Khateeb, Jacqueline K Limberg, Jill N Barnes, Michael J Joyner, Nisha Charkoudian, Timothy B Curry
PURPOSE: Obese adults exhibit increased levels of inflammation, which may negatively affect blood pressure regulation. Based on existing literature, we hypothesized: (1) baroreflex sensitivity would be lower in obese adults when compared to lean adults; (2) acute ibuprofen (IBU, a cyclooxygenase inhibitor and nonsteroidal antiinflammatory agent) administration would increase baroreflex sensitivity in obese adults, with no effect in lean adults. METHODS: Seven lean (4 male, 3 female) and six obese (5 M, 1 F) adults completed two visits randomized to control (CON) or IBU (800 mg oral)...
February 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27752785/dexmedetomidine-for-refractory-adrenergic-crisis-in-familial-dysautonomia
#18
Ryan C Dillon, Jose-Alberto Palma, Christy L Spalink, Diana Altshuler, Lucy Norcliffe-Kaufmann, David Fridman, John Papadopoulos, Horacio Kaufmann
OBJECTIVE: Adrenergic crises are a cardinal feature of familial dysautonomia (FD). Traditionally, adrenergic crises have been treated with the sympatholytic agent clonidine or with benzodiazepines, which can cause excessive sedation and respiratory depression. Dexmedetomidine is a centrally-acting α 2-adrenergic agonist with greater selectivity and shorter half-life than clonidine. We evaluated the preliminary effectiveness and safety of intravenous dexmedetomidine in the treatment of refractory adrenergic crisis in patients with FD...
February 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27734180/assessment-of-autonomic-symptoms-in-a-medically-complex-urban-patient-population
#19
Jessica Robinson-Papp, Sandeep K Sharma, Mary Catherine George, David M Simpson
PURPOSE: Urban, minority communities are disproportionately affected by the chronic diseases associated with autonomic neuropathy; however validated measures of autonomic symptoms have not been studied in these complex populations. We sought to validate the Autonomic Symptom Profile (ASP) in a low income, medically complex, urban patient population. METHODS: Ninety-seven adults were recruited from the outpatient neurology clinic of an academic medical center serving the East Harlem neighborhood of New York City...
February 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27761674/autonomic-dysfunction-in-pediatric-patients-with-headache-migraine-versus-tension-type-headache
#20
Jonathan Rabner, Alessandra Caruso, David Zurakowski, Lori Lazdowsky, Alyssa LeBel
PURPOSE: To examine symptoms indicating central nervous system (CNS) autonomic dysfunction in pediatric patients with migraine and tension-type headache. METHODS: A retrospective chart review assessed six symptoms (i.e. constipation, insomnia, dizziness, blurry vision, abnormal blood pressure, and cold and clammy palms and soles) indicating central nervous system (CNS) autonomic dysfunction in 231 patients, ages 5-18 years, diagnosed with migraine, tension-type headache (TTH), or Idiopathic Scoliosis (IS)...
December 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
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