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Journal of Magnetic Resonance Imaging: JMRI

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https://www.readbyqxmd.com/read/30408268/quantitative-radiomic-biomarkers-for-discrimination-between-neuromyelitis-optica-spectrum-disorder-and-multiple-sclerosis
#1
Xiaoxiao Ma, Liwen Zhang, Dehui Huang, Jinhao Lyu, Mengjie Fang, Jianxing Hu, Yali Zang, Dekang Zhang, Hang Shao, Lin Ma, Jie Tian, Di Dong, Xin Lou
BACKGROUND: Precise diagnosis and early appropriate treatment are of importance to reduce neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) morbidity. Distinguishing NMOSD from MS based on clinical manifestations and neuroimaging remains challenging. PURPOSE: To investigate radiomic signatures as potential imaging biomarkers for distinguishing NMOSD from MS, and to develop and validate a diagnostic radiomic-signature-based nomogram for individualized disease discrimination...
November 8, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390401/correlation-between-tumor-glucose-metabolism-and-multiparametric-functional-mri-ivim-and-r2-metrics-in-cervical-carcinoma-evidence-from-integrated-18-f-fdg-pet-mr
#2
Zhang Li-Ou, Sun Hong-Zan, Bai Xiao-Xi, Chen Zhong-Wei, Lu Zai-Ming, Xin Jun, Guo Qi-Yong
BACKGROUND: Multiparameter, multimodality 18 F-FDG PET/MRI holds great potential for the diagnosis of cervical cancer based on the correlation between tumor glucose metabolism and imaging parameters. PURPOSE: To characterize the heterogeneity of tumor glucose metabolism by evaluating the correlation between 18 F-FDG uptake parameters and multiparametric functional MRI metrics in cervical carcinoma. STUDY TYPE: Retrospective. POPULATION: Fifty-four patients with cervical carcinoma...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390383/role-of-texture-analysis-in-breast-mri-as-a-cancer-biomarker-a-review
#3
Rhea D Chitalia, Despina Kontos
Breast cancer is a known heterogeneous disease. Current clinically utilized histopathologic biomarkers may undersample tumor heterogeneity, resulting in higher rates of misdiagnosis for breast cancer. MRI can provide a whole-tumor sampling of disease burden and is widely utilized in clinical care. Texture analysis can provide a localized description of breast cancer, with particular emphasis on quantifying breast lesion heterogeneity. The object of this review is to provide an overview of texture analysis applications towards breast cancer diagnosis, prognosis, and treatment response evaluation and review the role of image-based texture features as noninvasive prognostic and predictive biomarkers...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390374/general-anesthesia-sedation-requirement-influences-the-way-mri-brain-scans-are-ordered-in-a-tertiary-pediatric-hospital
#4
Min Yi Sum, Kathy Low, Phua Hwee Tang
BACKGROUND: MRI guidelines have been created to help clinicians order scans appropriately. Some scans in children are carried out under general anesthesia (GA) / sedation. PURPOSE: To evaluate if the requirement for GA/sedation influences the way MRI brain scans are ordered. STUDY TYPE: Retrospective. POPULATION: Children with MRI brain scans in 2015 to 2017. FIELD STRENGTH: 3T, 1.5T. ASSESSMENT: Institutional Review Board approval for waiver of consent was obtained...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390367/cerebral-mr-oximetry-during-acetazolamide-augmentation-beyond-cerebrovascular-reactivity-in-hemodynamic-failure
#5
Christopher Leatherday, Seena Dehkharghani, Fadi Nahab, Jason W Allen, Junjie Wu, Ranliang Hu, Deqiang Qiu
BACKGROUND: Oxygen extraction fraction (OEF) elevation predicts increased ischemic stroke incidence among patients with carotid steno-occlusive disease, and can be estimated from quantitative susceptibility mapping (QSM) MRI. PURPOSE: To explore QSM oximetry during acetazolamide (ACZ) challenge, hypothesizing that detectable OEF alterations will reflect hemodynamic compromise in unilateral cerebrovascular disease (CVD) patients. STUDY TYPE: Retrospective...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390366/in-vitro-distinction-between-proinflammatory-and-antiinflammatory-macrophages-with-gadolinium-liposomes-and-ultrasmall-superparamagnetic-iron-oxide-particles-at-3-0t
#6
Wassef Khaled, Joao Piraquive, Benjamin Leporq, Jing Hong Wan, Simon A Lambert, Nathalie Mignet, Bich-Thuy Doan, Sophie Lotersztajn, Philippe Garteiser, Bernard E Van Beers
BACKGROUND: Inflammation involves a heterogeneous macrophage population, for which there is no readily available MR assessment method. PURPOSE: To assess the feasibility of distinguishing proinflammatory M1 and antiinflammatory M2 macrophages at MRI enhanced with gadolinium liposomes or ultrasmall superparamagnetic iron oxide particles. STUDY TYPE: In vitro. SPECIMEN: We employed cultured RAW macrophages. M0 macrophages were polarized with lipopolysaccharide (LPS) or interleukin-4 (IL-4), resulting in M1 or M2 macrophages...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390364/a-study-of-the-correlation-of-perfusion-parameters-in-high-resolution-grasp-mri-with-microvascular-density-in-lung-cancer
#7
Lihua Chen, Xianchun Zeng, Youli Wu, Xiaochu Yan, Xuequan Huang, Hui Chen, Jiuquan Zhang, Jian Wang, Li Feng
BACKGROUND: The histological count of microvascular density (MVD) is the current clinical standard for assessing tumor angiogenesis. Although it is hypothesized that perfusion MRI can be a noninvasive alternative to MVD, there have been few studies to validate their correlations, particularly in lung cancer. PURPOSE: To investigate the correlation between MVD and perfusion parameters obtained from high-resolution GRASP (Golden-angle RAdial Sparse Parallel) dynamic contrast-enhanced (DCE)-MRI in a cohort of lung cancer patients, and to validate that GRASP MRI can serve as a free-breathing, noninvasive imaging approach for studying tumor angiogenesis...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390363/visualizing-wall-enhancement-over-time-in-unruptured-intracranial-aneurysms-using-3d-vessel-wall-imaging
#8
Bing Tian, Shahed Toossi, Laura Eisenmenger, Farshid Faraji, Megan K Ballweber, S Andrew Josephson, Henrik Haraldsson, Chengcheng Zhu, Sinyeob Ahn, Gerhard Laub, Christopher Hess, David Saloner
BACKGROUND: Few studies directed at assessing the visualization of the walls of unruptured aneurysms have used higher-resolution 3D MRI vessel wall imaging. Prospective longitudinal studies are also needed to screen vessel wall changes in unruptured aneurysms. PURPOSE: To compare the aneurysm wall visualization on pre- and post-3D isotropic T1 -weighted Sampling Perfection with Application-optimized Contrasts by using different flip angle Evolutions (SPACE) images and to explore whether there is a change in wall enhancement at follow up...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390360/prediction-of-abnormal-bone-density-and-osteoporosis-from-lumbar-spine-mr-using-modified-dixon-quant-in-257-subjects-with-quantitative-computed-tomography-as-reference
#9
Yinxia Zhao, Mingqian Huang, Jie Ding, Xintao Zhang, Karl Spuhler, Shaoyong Hu, Mianwen Li, Wei Fan, Lin Chen, Xiaodong Zhang, Shaolin Li, Quan Zhou, Chuan Huang
BACKGROUND: Bone marrow fat increases when bone mass decreases, which could be attributed to the fact that adipogenesis competes with osteogenesis. Bone marrow fat has the potential to predict abnormal bone density and osteoporosis. PURPOSE: To investigate the predictive value of using vertebral bone marrow fat fraction(BMFF) obtained from modified Dixon(mDixon) Quant in the determination of abnormal bone density and osteoporosis. STUDY TYPE: Prospective...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390353/patient-specific-requirements-and-clinical-validation-of-mri-based-pressure-mapping-a-two-center-study-in-patients-with-aortic-coarctation
#10
Leonid Goubergrits, Florian Hellmeier, Dominik Neumann, Viorel Mihalef, Mehmet A Gulsun, Marcello Chinali, Aurelio Secinaro, Kilian Runte, Stephan Schubert, Felix Berger, Titus Kuehne, Anja Hennemuth, Marcus Kelm
BACKGROUND: Invasive peak-to-peak pressure gradients are the current clinical reference standard for assessing aortic coarctation. To obtain them, patients need to undergo arterial heart catheterization. Unless an intervention is performed, the procedure remains purely diagnostic, while the concomitant risks remain. PURPOSE: To validate MRI-based pressure mapping against pressure drop derived from heart catheterization and to define minimal clinical requirements...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390347/assessment-of-uterine-artery-geometry-and-hemodynamics-in-human-pregnancy-with-4d-flow-mri-and-its-correlation-with-doppler-ultrasound
#11
Eileen Hwuang, Marta Vidorreta, Nadav Schwartz, Brianna F Moon, Kirpal Kochar, Matthew Dylan Tisdall, John A Detre, Walter R T Witschey
BACKGROUND: Uterine artery (UtA) hemodynamics might be used to predict risk of hypertensive pregnancy disorders, including preeclampsia and intrauterine growth restriction. PURPOSE OR HYPOTHESIS: To determine the feasibility of 4D flow MRI in pregnant subjects by characterizing UtA anatomy, computing UtA flow, and comparing UtA velocity, and pulsatility and resistivity indices (PI, RI) with transabdominal Doppler ultrasound (US). STUDY TYPE: Prospective cross-sectional study from June 6, 2016, to May 2, 2018...
November 3, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30390358/view-sharing-artifact-reduction-with-retrospective-compressed-sensing-reconstruction-in-the-context-of-contrast-enhanced-liver-mri-for-hepatocellular-carcinoma-hcc-screening
#12
Jamil Shaikh, Paul B Stoddard, Evan G Levine, Albert T Roh, Manojkumar Saranathan, Stephanie T Chang, Michael C Muelly, Brian A Hargreaves, Shreyas S Vasanawala, Andreas M Loening
BACKGROUND: View-sharing (VS) increases spatiotemporal resolution in dynamic contrast-enhanced (DCE) MRI by sharing high-frequency k-space data across temporal phases. This temporal sharing results in respiratory motion within any phase to propagate artifacts across all shared phases. Compressed sensing (CS) eliminates the need for VS by recovering missing k-space data from pseudorandom undersampling, reducing temporal blurring while maintaining spatial resolution. PURPOSE: To evaluate a CS reconstruction algorithm on undersampled DCE-MRI data for image quality and hepatocellular carcinoma (HCC) detection...
November 2, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30375702/multiparametric-mri-model-with-dynamic-contrast-enhanced-and-diffusion-weighted-imaging-enables-breast-cancer-diagnosis-with-high-accuracy
#13
Michelle Zhang, Joao V Horvat, Blanca Bernard-Davila, Maria Adele Marino, Doris Leithner, R Elena Ochoa-Albiztegui, Thomas H Helbich, Elizabeth A Morris, Sunitha Thakur, Katja Pinker
BACKGROUND: The MRI Breast Imaging-Reporting and Data System (BI-RADS) lexicon recommends that a breast MRI protocol contain T2 -weighted and dynamic contrast-enhanced (DCE) MRI sequences. The addition of diffusion-weighted imaging (DWI) significantly improves diagnostic accuracy. This study aims to clarify which descriptors from DCE-MRI, DWI, and T2 -weighted imaging are most strongly associated with a breast cancer diagnosis. PURPOSE/HYPOTHESIS: To develop a multiparametric MRI (mpMRI) model for breast cancer diagnosis incorporating American College of Radiology (ACR) BI-RADS recommended descriptors for breast MRI with DCE, T2 -weighted imaging, and DWI with apparent diffusion coefficient (ADC) mapping...
October 30, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30362652/mr-based-radiomics-nomogram-of-cervical-cancer-in-prediction-of-the-lymph-vascular-space-invasion-preoperatively
#14
Zhicong Li, Hailin Li, Shiyu Wang, Di Dong, Fangfang Yin, An Chen, Siwen Wang, Guangming Zhao, Mengjie Fang, Jie Tian, Sufang Wu, Han Wang
BACKGROUND: Lymph-vascular space invasion (LVSI) is an unfavorable prognostic factor in cervical cancer. Unfortunately, there are no current clinical tools for the preoperative prediction of LVSI. PURPOSE: To develop and validate an axial T1 contrast-enhanced (CE) MR-based radiomics nomogram that incorporated a radiomics signature and some clinical parameters for predicting LVSI of cervical cancer preoperatively. STUDY TYPE: Retrospective...
October 26, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30358001/ultrashort-echo-time-imaging-for-quantification-of-hepatic-iron-overload-comparison-of-acquisition-and-fitting-methods-via-simulations-phantoms-and-in-vivo-data
#15
Aaryani Tipirneni-Sajja, Ralf B Loeffler, Axel J Krafft, Andrea N Sajewski, Robert J Ogg, Jane S Hankins, Claudia M Hillenbrand
BACKGROUND: Current R2*-MRI techniques for measuring hepatic iron content (HIC) use various acquisition types and fitting models. PURPOSE: To evaluate the accuracy and precision of R2*-HIC acquisition and fitting methods. STUDY TYPE: Signal simulations, phantom study, and prospective in vivo cohort. POPULATION: In all, 132 patients (58/74 male/female, mean age 17.7 years). FIELD STRENGTH/SEQUENCE: 2D-multiecho gradient-echo (GRE) and ultrashort echo time (UTE) acquisitions at 1...
October 25, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30353990/current-state-of-mri-of-the-fetal-brain-in-utero
#16
REVIEW
Deborah A Jarvis, Paul D Griffiths
In this article we provide an overview of fetal brain development, describe the range of more common fetal neuropathology, and discuss the relevance of in utero MR (iuMR). Although ultrasonography remains the mainstay of fetal brain imaging, iuMR imaging is both feasible and safe, but presents several challenges. We discuss those challenges, the techniques employed to overcome them, and new approaches that may extend the clinical applicability of fetal iuMR. Level of Evidence: Technical Efficacy Stage. J. Magn...
October 24, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30353969/using-mri-to-study-the-alterations-in-liver-blood-flow-perfusion-and-oxygenation-in-response-to-physiological-stress-challenges-meal-hyperoxia-and-hypercapnia
#17
Eleanor F Cox, Naaventhan Palaniyappan, Guruprasad P Aithal, I Neil Guha, Susan T Francis
BACKGROUND: Noninvasive assessment of dynamic changes in liver blood flow, perfusion, and oxygenation using MRI may allow detection of subtle hemodynamic alterations in cirrhosis. PURPOSE: To assess the feasibility of measuring dynamic liver blood flow, perfusion, and T2 * alterations in response to meal, hypercapnia, and hyperoxia challenges. STUDY TYPE: Prospective. SUBJECTS: Ten healthy volunteers (HV) and 10 patients with compensated cirrhosis (CC)...
October 24, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30353967/role-of-proton-mr-spectroscopy-in-the-differentiation-of-borderline-from-malignant-epithelial-ovarian-tumors-a-preliminary-study
#18
Feng Hua Ma, Yong Ai Li, Jia Liu, Hai Ming Li, Guo Fu Zhang, Jin Wei Qiang
BACKGROUND: Due to the overlapping imaging appearances between borderline and malignant epithelial ovarian tumors (EOTs), borderline EOTs often represent a diagnostic challenge on conventional MRI. Proton magnetic resonance spectroscopy (1 H-MRS) might have potential to differentiate borderline from malignant tumors. PURPOSE: To investigate the ability of 1 H-MRS to differentiate borderline from malignant EOTs. STUDY TYPE: Prospective. POPULATION: In all, 278 patients with adnexal masses...
October 24, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30353959/quantification-of-biventricular-strain-and-assessment-of-ventriculo-ventricular-interaction-in-pulmonary-arterial-hypertension-using-exercise-cardiac-magnetic-resonance-imaging-and-myocardial-feature-tracking
#19
Aaron C W Lin, Helen Seale, Christian Hamilton-Craig, Norman R Morris, Wendy Strugnell
BACKGROUND: Right ventricular (RV) failure is the main cause of mortality in pulmonary arterial hypertension (PAH). Exercise testing helps identify early RV maladaptation and systolic dysfunction and facilitates therapy. Myocardial strain has been shown to be more sensitive than ejection fraction (EF) in detecting subclinical ventricular contractile dysfunction. Chronic pressure overload in PAH had been associated with changes in left ventricular (LV) filling. PURPOSE: To compare biventricular strains and ventriculo-ventricular interaction in PAH and controls using cardiac magnetic resonance feature tracking (cMRI-FT) and to determine the reproducibility of strain analysis...
October 24, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30353957/curved-planar-reformatting-and-convolutional-neural-network-based-segmentation-of-the-small-bowel-for-visualization-and-quantitative-assessment-of-pediatric-crohn-s-disease-from-mri
#20
Yechiel Lamash, Sila Kurugol, Moti Freiman, Jeannette M Perez-Rossello, Michael J Callahan, Athos Bousvaros, Simon K Warfield
BACKGROUND: Contrast-enhanced MRI of the small bowel is an effective imaging sequence for the detection and characterization of disease burden in pediatric Crohn's disease (CD). However, visualization and quantification of disease burden requires scrolling back and forth through 3D images to follow the anatomy of the bowel, and it can be difficult to fully appreciate the extent of disease. PURPOSE: To develop and evaluate a method that offers better visualization and quantitative assessment of CD from MRI...
October 24, 2018: Journal of Magnetic Resonance Imaging: JMRI
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