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Clinical Oral Implants Research

Jun-Yu Shi, Feng-Yuan Xu, Long-Fei Zhuang, Ying-Xin Gu, Shi-Chong Qiao, Hong-Chang Lai
OBJECTIVE: The aim of this study was to evaluate the long-term survival, complications, peri-implant conditions, marginal bone loss, and patient satisfaction of fixed dental prostheses supported by narrow diameter implants (NDIs) in the posterior jaws. MATERIALS AND METHODS: This study was designed as a retrospective cohort study with a mean follow-up time of 10.1 years (SD: 2.5 years). Patients receiving NDIs in posterior jaw were reviewed. Implant survival, hardware complication, modified plaque index (mPI), peri-implant probing depth (PPD), percentage of bleeding on probing (BOP%), marginal bone loss (MBL), and patient satisfaction were evaluated...
August 28, 2017: Clinical Oral Implants Research
Nikolaos Donos, Attila Horvath, Luis André Mezzomo, Dina Dedi, Elena Calciolari, Nikos Mardas
OBJECTIVES: To compare the radiographic bone changes, clinical parameters and aesthetic outcomes of immediately provisionalised and conventionally restored implants at 12- and 24-months post-implant placement. MATERIAL AND METHODS: In 24 patients, 24 bone level implants with a hydrophilic (SLActive) surface were placed in healed sites and they were either immediately provisionalised with a non-occluding temporary crown (test group) or left without a crown (control group)...
August 21, 2017: Clinical Oral Implants Research
Nejat Nizam, Gülnihal Eren, Aliye Akcalı, Nikolaos Donos
OBJECTIVES: To evaluate the effect of leukocyte and platelet-rich fibrin (L-PRF) in combination with deproteinized bovine bone mineral (DBBM) on bone regeneration in maxillary sinus augmentation. MATERIAL AND METHODS: Thirteen patients (nine males and four females, mean age ± SD; 49.92 ± 10.37) were enrolled to the study. 26 maxillary sinus augmentation procedures were randomly performed using DBBM and L-PRF mixture (test) or DBBM alone (control) in a split-mouth design...
August 8, 2017: Clinical Oral Implants Research
Xavier Costa-Berenguer, Marta García-García, Alba Sánchez-Torres, Mariano Sanz-Alonso, Rui Figueiredo, Eduard Valmaseda-Castellón
OBJECTIVE: To assess the effect of implantoplasty on the fracture resistance, surface roughness, and macroscopic morphology of standard diameter (4.1 mm) external connection dental implants. MATERIALS AND METHODS: An in vitro study was conducted in 20 screw-shaped titanium dental implants with an external connection. In 10 implants, the threads and surface were removed and polished with high-speed burs (implantoplasty), while the remaining 10 implants were used as controls...
July 23, 2017: Clinical Oral Implants Research
Kristina Bertl, Michael H Bertl, Patrick Heimel, Maria Burt, André Gahleitner, Andreas Stavropoulos, Christian Ulm
OBJECTIVES: To compare the alveolar bone dimensions in patients with lower second premolar (P2) agenesis prior to and after primary molar loss on CT scans, and assess the possibility for straightforward implant placement. METHODS: Alveolar bone dimensions were evaluated on 150 mandibular CT scans in three groups: (i) agenesis of P2, with the primary tooth in situ, and regularly erupted first premolar (P1) and molar (M1) (AW); (ii) agenesis of P2, without the primary tooth in situ for ≥3 m, but regularly erupted P1 and M1 (AWO); and (iii) P1, P2, and M1 regularly erupted (CTR)...
July 23, 2017: Clinical Oral Implants Research
Víctor Paredes, Rosa María López-Pintor, Jesús Torres, Juan Carlos de Vicente, Mariano Sanz, Gonzalo Hernández
OBJECTIVES: The main objective of this prospective study was to evaluate the long-term outcome of implant therapy in liver transplant patients (LTP). The secondary goal was to assess several implant- and patient-dependent variables, such as peri-implantitis (PI), peri-implant mucositis (PIM), bone loss (BL), and immediate postoperative complications. MATERIAL AND METHODS: Two groups, including 16 pharmacologically immunosuppressed LTP and 16 matched controls, received 52 and 54 implants, respectively, between 1999 and 2008...
July 21, 2017: Clinical Oral Implants Research
M Retzepi, E Calciolari, I Wall, M P Lewis, N Donos
OBJECTIVES: To investigate the effect of experimental diabetes and metabolic control on intramembranous bone healing following guided bone regeneration (GBR). MATERIAL AND METHODS: Ninety-three Wistar rats were allocated to three experimental groups, healthy (H), uncontrolled diabetes (D) and controlled diabetes (CD). Twenty one days following diabetes induction, a standardised 5-mm defect was created at the mid-portion of each parietal bone. In 75 animals (25H, 25D, 25CD), one defect was treated with an intracranial and extracranial membrane according to the GBR principle, and one defect was left empty (control); five animals per group were then randomly sacrificed at 3, 7, 15, 30 and 60 days and processed for decalcified histology...
July 18, 2017: Clinical Oral Implants Research
Alberto Ortiz-Vigón, Iñaki Suarez, Sergio Martínez-Villa, Ignacio Sanz-Martín, Juan Bollain, Mariano Sanz
OBJECTIVES: To evaluate the performance and safety of placing a collagenated xenogeneic bone block (CXBB) graft for the lateral bone augmentation of the alveolar crest prior to implant placement. MATERIAL & METHODS: In patients with single or multiple tooth gaps and a severe horizontal collapse of the alveolar ridge, a ridge augmentation procedure was performed using CXBB fixated with osteosynthesis screws to the atrophic bone crest and complemented with deproteinized bovine bone mineral particles (DBBM) and a native bilayer collagen membrane (NBCM)...
July 14, 2017: Clinical Oral Implants Research
Adham Elsayed, Sebastian Wille, Majed Al-Akhali, Matthias Kern
OBJECTIVE: The aim of this study was to test five types of implant restorations using titanium, zirconia and lithium disilicate abutments after being subjected to long-term fatigue loading. MATERIALS AND METHODS: Forty single-tooth implant restorations were assembled on titanium implants (FairTwo; FairImplant). The restorations differed only in the type of abutment used and were divided into five groups [Ti: titanium; Zr: zirconia with no metal base; ZrT: zirconia with titanium base; LaT: lithium disilicate abutment with titanium base; and LcT: lithium disilicate hybrid-abutment-crown with titanium base]...
June 30, 2017: Clinical Oral Implants Research
Goran I Benic, Daniel S Thoma, Ignacio Sanz-Martin, Fernando Munoz, Christoph H F Hämmerle, Antonio Cantalapiedra, Jens Fischer, Ronald E Jung
AIM: To test whether guided bone regeneration (GBR) of peri-implant defects at zirconia (ZrO2 ) implants differs from GBR at titanium (Ti) implants regarding the bone integration of the implant and of the grafting material. MATERIALS AND METHODS: Maxillary premolars and molars were extracted in seven dogs. After 5 months, four semi-saddle bone defects were created in each maxilla. Implant placement and simultaneous GBR were performed using the following randomly assigned modalities: (1) ZrO2 implant + deproteinized bovine bone mineral (DBBM) granules + a collagen membrane (CM), (2) ZrO2 implant + DBBM with 10% collagen matrix + CM, (3) ZrO2 implant + DBBM block + CM, and (4) Ti implant + DBBM granules + CM...
June 26, 2017: Clinical Oral Implants Research
E Calciolari, N Mardas, X Dereka, A K Anagnostopoulos, G T Tsangaris, N Donos
OBJECTIVES: To identify and describe protein expression in a Wistar rat calvarial critical size defect (CSD) model following treatment with guided bone regeneration in healthy and osteoporotic conditions. MATERIAL AND METHODS: Thirty-six 10-month-old female Wistar rats were used. Half of them were ovariectomized (OVX) and fed with a low-calcium diet to induce an osteoporotic-like status. In each animal of both groups, two 5-mm calvarial CSDs were treated with deproteinized bovine bone mineral graft particles and a bilayer collagen membrane...
September 2017: Clinical Oral Implants Research
Reinhard Gruber, Bernd Stadlinger, Hendrik Terheyden
This overview provides insights into the molecular and cellular mechanisms involved in guided bone regeneration, in particular focusing on aspects presented in the 3D movie, Cell-To-Cell Communication in Guided Bone Regeneration. The information presented here is based almost exclusively on genetic mouse models in which single genes can be deleted or overexpressed, even in a specific cell type. This information needs to be extrapolated to humans and related to aspects relevant to graft consolidation under the clinical parameters of guided bone regeneration...
September 2017: Clinical Oral Implants Research
France Lambert, Gaëlle Botilde, Geoffrey Lecloux, Eric Rompen
AIMS: The objective of this study was to assess prospectively the outcomes of extra-narrow diameter implants (XNDI) placed in teenage patients as a temporary restorative option. MATERIAL AND METHODS: Twenty consecutive young patients presenting one or several missing teeth received XNDI that were immediately restored with composite, Polymethylmethacrylate (Acrylic) or ceramic crown. Clinical and radiographical outcomes were assessed for a minimum follow-up period of 1 year...
September 2017: Clinical Oral Implants Research
Elena Calciolari, Nikos Mardas, Xanthippi Dereka, Nikolaos Kostomitsopoulos, Aviva Petrie, Nikolaos Donos
OBJECTIVES: To histologically define the healing events occurring in calvarial critical size defects (CSDs) following treatment with a collagen barrier for guided bone regeneration (GBR) and a particulate graft in healthy and osteoporotic conditions. MATERIAL AND METHODS: Thirty-six 10-month-old, female, Wistar rats were used in this study. Half of them were ovariectomized (OVX) and fed with a low-calcium diet to induce an osteoporotic-like status. In each animal of both groups, two 5-mm CSDs were created, one in the centre of each parietal bone, and they were treated with a deproteinized bovine bone mineral (DBBM) particulate graft and a bi-layer collagen membrane...
September 2017: Clinical Oral Implants Research
M Menini, E Dellepiane, D Baldi, M G Longobardi, P Pera, A Izzotti
OBJECTIVES: This split-mouth study evaluated miRNA expression of tissues around implants with different surface treatments. MATERIAL AND METHODS: Each patient of the sample (five men and five women) received two implants (one control and one test) into an edentulous quadrant to support fixed partial dentures. The control implants (Osseotite) had a dual acid-etched (DAE) surface in the apical portion and a machined coronal part, test implants (Full Osseotite, FOSS) were completely DAE...
September 2017: Clinical Oral Implants Research
Miriam López-Álvarez, Eva Vigo, Cosme Rodríguez-Valencia, Verónica Outeiriño-Iglesias, Pío González, Julia Serra
OBJECTIVE: The present work proposes the shark teeth as a new source of bioapatites for bone filler applications in maxillary sinus elevation, periodontal regeneration or implants placement. This abundant fishing by-product provides an improved hydroxyapatite (HA) with fluorine contributions. The in vivo evaluation of osteointegration and bone mineral density levels promoted by these marine bioapatites was the main objective. MATERIALS AND METHODS: Marine bioapatite granules of two sizes (1 mm, <20 μm) were obtained and characterized (XRD, SEM, ICP-OES) to determine morphology and composition...
September 2017: Clinical Oral Implants Research
Veli Özgen Öztürk, Gülnur Emingil, Nagihan Bostanci, Georgios N Belibasakis
OBJECTIVES: The study aimed to determine the levels of soluble receptor activator of nuclear factor-кB ligand (sRANKL) and osteoprotegerin (OPG) as well as their relative calculated ratio in peri-implant crevicular fluid (PICF) obtained around two different types of implant-abutment connection on short implants following a 12-month monitoring period. Moreover, the levels of a number of oral bacterial species were investigated in the corresponding submucosal biofilm samples. MATERIALS AND METHODS: Thirty short implants were randomly placed in posterior maxillary edentulous sites using a split-mouth design in 15 periodontally healthy subjects...
September 2017: Clinical Oral Implants Research
V Laederach, K Mukaddam, M Payer, A Filippi, S Kühl
OBJECTIVES: To compare the deviation of different systems for Guided Implant Surgery (GIS) related to the specific tolerance between drills and sleeves. MATERIAL AND METHODS: Four different systems for GIS and their appropriate sleeves were used: Camlog Guide (CG), Straumann Guided Surgery (SG), SIC Guide (SIG), and NobelGuide (NG). System-appropriate metal sleeves were inserted into plexiglass boxes, and guided drilling procedure was performed (i) holding the drills in the most centric position of the sleeves and (ii) applying forces eccentrically...
September 2017: Clinical Oral Implants Research
Hyung Soo Kim, Jae In Lee, Sun Sik Yang, Beom Su Kim, Bong Chul Kim, Jun Lee
OBJECTIVE: Rapid and stable fixation of dental implants is crucial for successful treatment. Herein, we examined whether the simultaneous treatment of titanium implants with ultraviolet (UV) and alendronate (ALN) synergistically improved the bone-to-implant contact. MATERIALS AND METHODS: We assessed the in vitro effects of UV radiation-treated (UV+/ALN-), ALN-soaked (UV-/ALN+), and UV radiation/ALN-treated (UV+/ALN+) titanium implants on cell proliferation, cytotoxicity, cell adhesion, and osteoblast differentiation using MG-63 osteoblast-like cells by the assays of MTS, live/dead, scanning electron microscopy (SEM), alkaline phosphatase (ALP) activity, and alizarin red S (AR-S) staining, respectively...
September 2017: Clinical Oral Implants Research
Frank Schwarz, Christian Claus, Kathrin Becker
OBJECTIVES: To assess the horizontal mucosal thickness (hMT) at healthy and diseased implant sites and correlate these measurements with respective probing depths (PD). MATERIALS AND METHODS: In 60 patients, hMT was assessed at the buccal aspect of healthy (n = 36) and diseased (peri-implant mucositis: n = 26; peri-implantitis: n = 167) implant sites using a validated ultrasonic A-scanner (Pirop(®) Ultrasonic Biometer A- Scan, Echo-Son, Krancowa, Poland) equipped with a specially designed tissue probe...
September 2017: Clinical Oral Implants Research
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