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Clinical Oral Implants Research

Michele Stocchero, Marco Toia, Yohei Jinno, Francesca Cecchinato, Jonas P Becktor, Yoshihito Naito, Anders Halldin, Ryo Jimbo
OBJECTIVE: The aim of this study was to investigate the extent of cortical bone remodeling between two different drilling protocols by means of histomorphometric, µ-CT, and biomechanical analyses. MATERIAL AND METHODS: A total of 48 implants were inserted into the mandible of six sheep following two drilling protocols: Group A (Test, n = 24), undersized preparation; Group B (Control, n = 24), non-undersized preparation. The animals were euthanatized to obtain 5 and 10 weeks of implantation time...
May 20, 2018: Clinical Oral Implants Research
Kai Zhao, Meifei Lian, Shengchi Fan, Wei Huang, Feng Wang, Yiqun Wu
OBJECTIVES: The purpose of this retrospective study was to evaluate the long-term changes in the thickness of Schneiderian membranes after zygomatic implant placement using cone beam computed tomography (CBCT). MATERIAL AND METHODS: Twenty-five consecutive patients were included in this study. All the patients underwent bilateral zygomatic implant placement. Schneiderian membrane thickness (SMT) in 49 maxillary sinuses (one sinus was not included because of early loss of the zygomatic implants) was measured using CBCT before and at least 1 year after zygomatic implant placement...
May 17, 2018: Clinical Oral Implants Research
Faustino Mercado, Stephen Hamlet, Saso Ivanovski
OBJECTIVES: There is limited evidence regarding the long-term efficacy of regenerative treatment for peri-implantitis. The aim of this study was to evaluate a combination therapy of deproteinized bovine bone mineral with 10% collagen (DBBMC), enamel matrix derivative (EMD) and Doxycycline in the regeneration of bone defects associated with peri-implantitis. METHODS: Thirty patients diagnosed with peri-implantitis (BoP/suppuration, probing depth greater than 4 mm, minimum radiographic bone loss of 20%, at least 2 years in function) were enrolled in the study...
May 16, 2018: Clinical Oral Implants Research
Jae-Kook Cha, Yoo-Kyung Sun, Myong Ji Kim, Mariano Sanz, Ui-Won Jung
AIM: The aim of this experimental in vivo investigation was to assess the anti-resorptive effect of low concentration pamidronate on the buccal plate in fresh extraction sockets. MATERIALS AND METHODS: The distal roots of the third premolars were extracted bilaterally in six dogs. A collagen matrix loaded with either pamidronate (test group) or saline (control group) was positioned on the outer surface of buccal bone immediately after tooth extraction and subsequently covered with a coronally advanced flap...
May 12, 2018: Clinical Oral Implants Research
Frank Schwarz, Jürgen Becker, Sara Civale, Didem Sahin, Theresa Iglhaut, Gerhard Iglhaut
OBJECTIVES: To analyze the influence of the width of keratinized mucosa (KM) on the development and resolution of experimental peri-implant mucositis lesions at abutments with different microstructures in humans. MATERIAL AND METHODS: In a randomized, controlled study, a total of 28 patients had received 28 target implants exhibiting a KM ≥2 mm. These were randomly connected with either partially microgrooved- (test) (n = 15) or machined (control) (n = 13) healing abutments...
April 24, 2018: Clinical Oral Implants Research
Luis Gallego, Alberto Sicilia, Pelayo Sicilia, Carmen Mallo, Susana Cuesta, Mariano Sanz
OBJECTIVE: To analyze retrospectively interproximal crestal bone loss (CBL) on external-hex "non-identical" (NI) dental implants with different surface topography, when placed in the same intra-oral location in patients with a history of chronic periodontitis following maintenance care. MATERIAL AND METHODS: The patient population consisted of 206 consecutive patients with a history of chronic periodontitis who underwent implant surgery between 2007 and 2010; 755 NI implants with different implant surfaces were placed at posterior mandibular sites: 72 machined, 145 acid-etched/machined (hybrid), and 538 anodized...
April 17, 2018: Clinical Oral Implants Research
Túlio Eduardo Nogueira, Fernanda Maria Oliveira Aguiar, Bento Alves de Barcelos, Cláudio Rodrigues Leles
OBJECTIVE: This prospective clinical trial aimed to assess clinical and patient-reported outcomes of the single-implant mandibular overdenture treatment (SIMO) after a 2-year follow-up period. MATERIALS AND METHODS: An external hexagon implant was inserted in the mandibular midline of 45 complete denture wearers. Participants had a mean age of 63.4 (SD = 8.3), and 75.6% were female. Based on the primary stability of the implant, immediate loading was performed in 38 patients (84...
April 16, 2018: Clinical Oral Implants Research
Ausra Ramanauskaite, Kathrin Becker, Frank Schwarz
OBJECTIVES: To evaluate and correlate clinical parameters associated with peri-implant diseases based on established case definitions. MATERIALS AND METHODS: A total of 75 patients exhibiting 269 implants (healthy: 77; peri-implant mucositis: 77; peri-implantitis: 115) were included in this observational study. Clinical parameters included bleeding on probing (BOP), probing depths (PDs), and suppuration (Supp). RESULTS: Healthy sites were associated with the absence of BOP, while mean BOP in peri-implant mucositis and peri-implantitis patients amounted to 20...
April 16, 2018: Clinical Oral Implants Research
Tobias Basler, Nadja Naenni, David Schneider, Christoph H F Hämmerle, Ronald E Jung, Daniel S Thoma
OBJECTIVES: To assess two- and three-dimensional changes of the peri-implant tissues as well as clinical, biological, and radiological outcomes of implants having been treated with resorbable or nonresorbable membranes at 3 years. MATERIALS AND METHODS: Twenty-three patients were re-examined after having received a single-tooth implant in the esthetic zone in conjunction with guided bone regeneration (GBR) using either a resorbable (RES) or a titanium-reinforced nonresorbable membrane (N-RES) and demineralized bovine bone mineral...
April 15, 2018: Clinical Oral Implants Research
Farahnaz Nejatidanesh, Omid Savabi, Ghazal Savabi, Mehdi Razavi
OBJECTIVE: The aim of this study was to evaluate the effect of different cleaning regimens on retentive strength of saliva-contaminated implant-supported zirconia copings. MATERIAL AND METHODS: Seventy solid titanium abutments with 5.5 mm height (Straumann) were attached to the regular neck implant analogs (Straumann). The abutment-analog complex was mounted vertically in an autopolymerized T-shaped acrylic resin block. Seventy zirconia copings with an occlusal loop were made...
April 15, 2018: Clinical Oral Implants Research
Marco N Helder, Fransisca A S van Esterik, Mardi D Kwehandjaja, Christiaan M Ten Bruggenkate, Jenneke Klein-Nulend, Engelbert A J M Schulten
OBJECTIVES: Synthetic biphasic calcium phosphate (BCP) with a hydroxyapatite/ß-tricalcium phosphate (HA/ß-TCP) ratio of 60/40 (BCP60/40) is successfully used as alternative for autologous bone in patients undergoing maxillary sinus floor elevation (MSFE) for dental implant placement. A high percentage of HA in BCP60/40 may hamper efficient scaffold remodeling. Osteogenesis and neovascularization are pivotal in effective bone regeneration. We aimed to investigate whether differences exist in osteogenic and/or vasculogenic potential of BCP60/40 and BCP20/80 in patients undergoing MSFE...
April 11, 2018: Clinical Oral Implants Research
Ronald E Jung, Vitor M Sapata, Christoph H F Hämmerle, Hui Wu, Xiu-Lian Hu, Ye Lin
AIM: The aim of this split-mouth randomized controlled study was to evaluate radiographic dimensional changes after tooth extraction in posterior sites treated with a ridge preservation technique or left for spontaneous healing. MATERIALS AND METHODS: In a total of 18 patients, tooth extraction in posterior sites of the upper and lower jaw was performed in a split-mouth design. The post-extraction sockets were randomly assigned to the following two treatment modalities: deproteinized bovine bone mineral (DBBM) with 10% collagen (DBBM-C) covered with a native bilayer collagen membrane (NBCM) (test group) and spontaneous healing (control group)...
April 1, 2018: Clinical Oral Implants Research
Cho-Ying Lin, Zhaozhao Chen, Whei-Lin Pan, Hom-Lay Wang
BACKGROUND: To achieve a predictable esthetic and functional outcome, soft tissue augmentation has become popular in implant treatment. OBJECTIVES: The aim of this systematic review and meta-analysis was to assess the influence of different timing for soft tissue augmentation during implant treatment on soft tissue conditions and its stability. MATERIAL AND METHODS: Electronic and manual searches for articles written in English up to September 2017 were performed by two independent reviewers...
March 30, 2018: Clinical Oral Implants Research
Georgios Pelekos, Aneesha Acharya, Maurizio S Tonetti, Michael M Bornstein
OBJECTIVES: To evaluate the diagnostic performance of cone beam computed tomography (CBCT) in the assessment of peri-implant bone loss and analyze its influencing factors. MATERIALS AND METHODS: Clinical and preclinical studies reporting diagnostic outcomes of CBCT imaging of peri-implant bone loss compared to direct reference measurements were sought by searching five electronic databases, PubMed, MEDLINE, EMBASE, Web of Science, and CINAHL Plus, and OpenGrey. QUADAS-2 criteria were adapted for quality analysis of the included studies...
March 26, 2018: Clinical Oral Implants Research
Tord Berglundh, Jan L Wennström, Jan Lindhe
OBJECTIVE: To assess long-term clinical and radiological outcomes of surgical treatment of peri-implantitis. MATERIAL AND METHODS: Files and radiographs from 50 patients who had received surgical treatment for peri-implantitis were analyzed. Data on clinical characteristics prior to surgical therapy and at latest follow-up were obtained. In each radiograph, the marginal bone level was assessed at the mesial and distal aspects of the affected implants. The treatment included oral hygiene instruction, professional supra-mucosal instrumentation, and surgical therapy aiming at pocket elimination...
March 25, 2018: Clinical Oral Implants Research
Mauro Donati, Annika Ekestubbe, Jan Lindhe, Jan L Wennström
OBJECTIVE: This report is a 20-year follow-up of a randomized controlled clinical trial evaluating the potential long-term effect of a modified implant surface on the preservation of the peri-implant marginal bone level. MATERIAL & METHODS: In each of 51 patients and for each fixed partial denture (FPD), by randomization at least one implant installed had a non-modified turned surface and one a modified and roughened surface (TiOblast® ). Clinical and radiological examinations were performed at various follow-up intervals...
March 23, 2018: Clinical Oral Implants Research
Claudio Stacchi, Teresa Lombardi, Roberto Ottonelli, Federico Berton, Giuseppe Perinetti, Tonino Traini
OBJECTIVE: The aim of this multicenter prospective study was to analyze clinically and histologically the influence of sinus cavity dimensions on new bone formation after transcrestal sinus floor elevation (tSFE). MATERIAL AND METHODS: Patients needing maxillary sinus augmentation (residual crest height <5 mm) were treated with tSFE using xenogeneic granules. Six months later, bone-core biopsies were retrieved for histological analysis in implant insertion sites...
March 23, 2018: Clinical Oral Implants Research
Felipe Anderson Sousa Nunes, Túlio B Pignaton, Arthur B Novaes, Mário Taba, Michel R Messora, Daniela B Palioto, Rubens Spin-Neto, Sérgio Luís Scombatti de Souza
OBJECTIVE: To evaluate the use of a synthetic bone substitute covered with a collagen membrane for ridge preservation after tooth extraction, by clinical and tomographic analysis. MATERIAL AND METHODS: Fifteen patients, presenting at least two maxillary anterior teeth indicated for extraction, were selected: in the test group (TG), post-extraction sockets were filled by a synthetic bone substitute; in the control group (CG), by blood clot. In both groups, the sockets were covered by a collagen membrane...
March 23, 2018: Clinical Oral Implants Research
Cristiano Tomasi, Mauro Donati, Denis Cecchinato, Isacco Szathvary, Enrico Corrà, Jan Lindhe
OBJECTIVE: To examine if (i) characteristics of the fresh extraction socket site influenced subsequent dimensional alterations and (ii) placement of deproteinized bovine mineral in the socket affected volumetric change during healing. MATERIALS AND METHODS: Twenty seven subjects and 28 extraction sites were included. Immediately after the removal of the tooth and after 6 months of healing, stone and virtual models of the jaw were produced. A cone beam computerized tomography scan was obtained immediately after extraction and the thickness of the buccal bone wall at the extraction site was measured...
March 13, 2018: Clinical Oral Implants Research
Irena Sailer, Asgeir G Asgeirsson, Daniel S Thoma, Vincent Fehmer, Thor Aspelund, Mutlu Özcan, Bjarni E Pjetursson
BACKGROUND: There is limited knowledge regarding the strength of zirconia abutments with internal and external implant abutment connections and zirconia abutments supported by a titanium resin base (Variobase, Straumann) for narrow diameter implants. OBJECTIVES: To compare the fracture strength of narrow diameter abutments with different types of implant abutment connections after chewing simulation. MATERIAL AND METHODS: Hundred and twenty identical customized abutments with different materials and implant abutment connections were fabricated for five groups: 1-piece zirconia abutment with internal connection (T1, Cares-abutment-Straumann BL-NC implant, Straumann Switzerland), 1-piece zirconia abutment with external hex connection (T2, Procera abutment-Branemark NP implant, Nobel Biocare, Sweden), 2-piece zirconia abutments with metallic insert for internal connection (T3, Procera abutment-Replace NP implant, Nobel Biocare), 2-piece zirconia abutment on titanium resin base (T4, LavaPlus abutment-VarioBase-Straumann BL-NC implant, 3M ESPE, Germany) and 1-piece titanium abutment with internal connection (C, Cares-abutment-Straumann BL-NC implant, Straumann, Switzerland)...
April 2018: Clinical Oral Implants Research
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