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Clinical Oral Implants Research

M Retzepi, E Calciolari, I Wall, M P Lewis, N Donos
OBJECTIVES: To investigate the effect of experimental diabetes and metabolic control on intramembranous bone healing following guided bone regeneration (GBR). MATERIAL AND METHODS: Ninety-three Wistar rats were allocated to three experimental groups, healthy (H), uncontrolled diabetes (D) and controlled diabetes (CD). Twenty one days following diabetes induction, a standardised 5-mm defect was created at the mid-portion of each parietal bone. In 75 animals (25H, 25D, 25CD), one defect was treated with an intracranial and extracranial membrane according to the GBR principle, and one defect was left empty (control); five animals per group were then randomly sacrificed at 3, 7, 15, 30 and 60 days and processed for decalcified histology...
July 18, 2017: Clinical Oral Implants Research
Alberto Ortiz-Vigón, Iñaki Suarez, Sergio Martínez-Villa, Ignacio Sanz-Martín, Juan Bollain, Mariano Sanz
OBJECTIVES: To evaluate the performance and safety of placing a collagenated xenogeneic bone block (CXBB) graft for the lateral bone augmentation of the alveolar crest prior to implant placement. MATERIAL & METHODS: In patients with single or multiple tooth gaps and a severe horizontal collapse of the alveolar ridge, a ridge augmentation procedure was performed using CXBB fixated with osteosynthesis screws to the atrophic bone crest and complemented with deproteinized bovine bone mineral particles (DBBM) and a native bilayer collagen membrane (NBCM)...
July 14, 2017: Clinical Oral Implants Research
Adham Elsayed, Sebastian Wille, Majed Al-Akhali, Matthias Kern
OBJECTIVE: The aim of this study was to test five types of implant restorations using titanium, zirconia and lithium disilicate abutments after being subjected to long-term fatigue loading. MATERIALS AND METHODS: Forty single-tooth implant restorations were assembled on titanium implants (FairTwo; FairImplant). The restorations differed only in the type of abutment used and were divided into five groups [Ti: titanium; Zr: zirconia with no metal base; ZrT: zirconia with titanium base; LaT: lithium disilicate abutment with titanium base; and LcT: lithium disilicate hybrid-abutment-crown with titanium base]...
June 30, 2017: Clinical Oral Implants Research
Goran I Benic, Daniel S Thoma, Ignacio Sanz-Martin, Fernando Munoz, Christoph H F Hämmerle, Antonio Cantalapiedra, Jens Fischer, Ronald E Jung
AIM: To test whether guided bone regeneration (GBR) of peri-implant defects at zirconia (ZrO2 ) implants differs from GBR at titanium (Ti) implants regarding the bone integration of the implant and of the grafting material. MATERIALS AND METHODS: Maxillary premolars and molars were extracted in seven dogs. After 5 months, four semi-saddle bone defects were created in each maxilla. Implant placement and simultaneous GBR were performed using the following randomly assigned modalities: (1) ZrO2 implant + deproteinized bovine bone mineral (DBBM) granules + a collagen membrane (CM), (2) ZrO2 implant + DBBM with 10% collagen matrix + CM, (3) ZrO2 implant + DBBM block + CM, and (4) Ti implant + DBBM granules + CM...
June 26, 2017: Clinical Oral Implants Research
Mario Roccuzzo, Dario Pittoni, Andrea Roccuzzo, Lorena Charrier, Paola Dalmasso
OBJECTIVES: The aim of this study was to evaluate the long-term results of the surgical treatment of single peri-implantitis intrabony defects, by means of deproteinized bovine bone mineral with 10% collagen (DBBMC). MATERIAL AND METHODS: The original population consisted of 26 patients with one crater-like defect, around either sandblasted and acid-etched (SLA) or titanium plasma-sprayed (TPS) dental implants, with a probing depth (PD) ≥6 mm and no implant mobility (Roccuzzo et al...
June 18, 2017: Clinical Oral Implants Research
Pablo Galindo-Moreno, Peter Nilsson, Paul King, Nils Worsaae, Alexander Schramm, Miguel Padial-Molina, Carlo Maiorana
OBJECTIVE: This study was initiated to evaluate the 5-year implant survival rate and marginal bone levels around a 3.0-mm implant when replacing a single tooth in the anterior region. MATERIALS AND METHODS: The study was designed as a prospective, single-arm, multicenter clinical study. Patients missing 12, 22, 32, 31, 41 or 42 teeth were included, and implants of 3.0 mm diameter and different lengths were placed by a one-stage surgery protocol. Definitive cemented crowns were placed 6-10 weeks later...
June 18, 2017: Clinical Oral Implants Research
E B Brahem, B Holm, L Sonnesen, N Worsaae, K Gotfredsen
OBJECTIVES: This follow-up study (1) compares tooth displacement of central incisors in patients with and without pre-implant orthodontic treatment and (2) investigates whether sex, age, or orthodontic retention have an effect on tooth displacement after the insertion of single-crown implants. MATERIALS AND METHODS: Fifty-seven patients - thirty-seven with (test group) and twenty without pre-implant orthodontic treatment (control group) - were rehabilitated with 89 single-crown implants in the upper maxilla...
June 18, 2017: Clinical Oral Implants Research
Takahisa Iida, Evandro Carneiro Martins Neto, Daniele Botticelli, Karol Alí Apaza Alccayhuaman, Niklaus P Lang, Samuel P Xavier
OBJECTIVE: To evaluate the healing after elevation of the sinus mucosa when a collagen membrane was placed between the sinus mucosa and a xenograft used as filler. MATERIALS AND METHODS: Eighteen rabbits were used. Sinus mucosa elevation was performed bilaterally, and a collagen membrane was applied subjacent to the sinus mucosa only at a randomly selected test site. At both sites, a collagenated corticocancellous porcine bone was placed within the elevated space and the access window was covered with a collagen membrane...
June 7, 2017: Clinical Oral Implants Research
Goran I Benic, Myung-Jae Joo, So-Ra Yoon, Jae-Kook Cha, Ui-Won Jung
OBJECTIVE: The aim of this pilot study was to test whether a porcine collagenated bone substitute block (PCBB) and collagen membrane (CM) loaded with bone morphogenetic protein-2 (BMP-2) used for horizontal ridge augmentation differ from PCBB and CM without BMP-2 regarding the osseointegration of the grafting material and the maintenance of the ridge contour. MATERIAL AND METHODS: Two semi-saddle bone defects were created in each side of the mandible of six dogs...
June 2, 2017: Clinical Oral Implants Research
Felix B Gamper, Goran I Benic, Ignacio Sanz-Martin, Asgeir G Asgeirsson, Christoph H F Hämmerle, Daniel S Thoma
OBJECTIVES: To test whether or not a one- (S1) and a two-piece (S2) dental implant systems render the same biological, technical, and esthetic outcomes regarding implants and implant-supported reconstructions over an observation period of 4 to 6 years. MATERIALS AND METHODS: Sixty patients were randomly assigned to receive S1 or S2 implants. The implants were restored with either fixed or removable prostheses. The insertion of the final reconstruction was chosen as baseline...
May 29, 2017: Clinical Oral Implants Research
Yun-Young Chang, Su-Hwan Kim, Keun-Oh Park, Jeong-Ho Yun
OBJECTIVES: The objective of this study was to investigate the effect of microthreads on the coronal bone healing of narrow-diameter implants with reverse-tapered design. MATERIAL AND METHODS: A total of 52 implants were classified into two groups according to presence or absence of coronal microthreads, the reverse-tapered narrow-diameter implant (RTN) group, and the reverse-tapered narrow-diameter implant with microthreads (RTNM) group. The implants were installed in split-mouth design in the edentulous mandible of six dogs...
May 22, 2017: Clinical Oral Implants Research
Kathrin Becker, Inka Klitzsch, Martin Stauber, Frank Schwarz
OBJECTIVES: To (i) assess the impact of insertion depth and abutment microstructure on the three-dimensional crestal bone-level changes at endosseous titanium implant using μCT and computerized image processing and (ii) to correlate the findings with previously reported histology. MATERIAL & METHODS: Titanium implants (conical abutment connection) were inserted in each hemimandible of n = 6 foxhounds with the implant shoulder (IS) located either in epicrestal (0 mm), supracrestal (+1 mm) or subcrestal (-1 mm) positions and randomly (split-mouth design) connected with machined or partially micro-grooved healing abutments...
June 2017: Clinical Oral Implants Research
Valerie H S Tey, Rachel Phillips, Ken Tan
OBJECTIVE: To analyze patients' perception of implant therapy in partial edentulism, after 5 years with implant-supported reconstructions. MATERIAL AND METHODS: Patients who received dental implants at the National Dental Centre, Singapore 3-9 years earlier (mean: 5.2 years) were invited to participate in the study. Responders were examined clinically, and asked to answer a questionnaire with 13 statements. RESULTS: Of the 880 patients, 206 patients, with 329 implants, agreed to participate...
June 2017: Clinical Oral Implants Research
Fabiana de Melo, Cássio do Nascimento, Diogo Onofre Souza, Rubens F de Albuquerque
OBJECTIVE: To characterize the profile of microbial communities colonizing titanium implants with different surface treatments after exposure to the oral environment at the genus or higher taxonomic level. MATERIAL AND METHODS: Sixteen titanium disks, machined or sandblasted large-grit and acid-etched (SLA), were mounted on removable intraoral splints worn by four patients. After 24 h of intraoral exposure, biofilm samples were collected from disks and supra/subgingival teeth areas...
June 2017: Clinical Oral Implants Research
Dina Suleimenova, Saeed M Hashimi, Ma Li, Saso Ivanovski, Nikos Mattheos
OBJECTIVES: The aim of this study was to investigate the gene expression profile related to guided bone regeneration (GBR) at the early healing stage while using combinations of different biomaterials. MATERIALS AND METHODS: Cranial defects in 4 New Zealand rabbits were filled with A) biphasic calcium phosphate/experimental pericardium-derived collagen membrane, B) Bio-Oss(®) /Bio-Gide(®) , C) biphasic calcium phosphate/strontium hydroxyapatite-containing collagen membrane and D) Bio-Oss(®) /strontium hydroxyapatite-containing collagen membrane...
June 2017: Clinical Oral Implants Research
Gyu-Un Jung, Jun Hwan Kim, Nam Hun Lim, Gil Ho Yoon, Ji-Young Han
OBJECTIVES: Ridge splitting techniques are used for horizontal ridge augmentation in implant dentistry. Recently, a novel engine-driven ridge splitting technique was introduced. This study compared the mechanical forces produced by conventional and engine-driven ridge splitting techniques in porcine mandibles. MATERIAL AND METHODS: In 33 pigs, mandibular premolar areas were selected for the ridge splitting procedures, designed as a randomized split-mouth study. The conventional group underwent a chisel-and-mallet procedure (control group, n = 20), and percussive impulse (Newton second, Ns) was measured using a sensor attached to the mallet...
June 2017: Clinical Oral Implants Research
Daniele Botticelli, Niklaus P Lang
OBJECTIVE: To investigate the sequential events of osseointegration in various model situations. MATERIAL AND METHODS: A series of eight recent sequential studies on the early phases of osseointegration performed in various species analyzing new bone apposition and parent bone resorption at the implant surfaces have been studied. One human, six dog and one rabbit studies were analyzed for old and new bone percentages, assessed at least at 4 periods of the early osseointegration...
June 2017: Clinical Oral Implants Research
Stefanie Raes, Filiep Raes, Lyndon Cooper, Luis Giner Tarrida, Stijn Vervaeke, Jan Cosyn, Hugo De Bruyn
OBJECTIVES: The impact of single implants on oral health-related quality of life (OHRQoL) is scarcely investigated, especially when combined with immediate placement and loading in extraction sockets. The aim was to describe prospectively the changes of OHRQoL with single implants placed in the esthetic zone in healed ridges or in extraction sockets after 5 years. MATERIAL AND METHODS: Ninety-six patients, enrolled at three clinical centers, received 102 single implants placed in a healed ridge (n = 54 implants/50 patients) or in extraction sockets (n = 48 implants/46 patients)...
June 2017: Clinical Oral Implants Research
Feng Wang, Wei Huang, Zhiyong Zhang, Haowei Wang, Alberto Monje, Yiqun Wu
PURPOSE: The purpose of this 2-year randomized controlled clinical trial was to assess the differences in implant survival rates, soft tissue preservation, patient centered outcome and crestal bone changes applying the minimally invasive (MI) flapless approach for single implant placement compared to flapped implant surgery (FS). MATERIALS AND METHODS: Subjects eligible for this study were randomly assigned into two groups: MI or FS. Items of evaluation were the following: implant installation position, soft tissue healing, post-surgical pain, soft tissue outcome, marginal bone loss (MBL), and implant survival rate...
June 2017: Clinical Oral Implants Research
Christian Mertens, Kolja Freier, Michael Engel, Johannes Krisam, Jürgen Hoffmann, Christian Freudlsperger
OBJECTIVES: Treatment of the severely atrophic maxilla with dental implants is challenging due to the insufficient horizontal and vertical bone volume and centripetal resorption pattern of the maxilla. Bone-augmentation procedures are often necessary prior to implant placement. The objective of this study was to assess the suitability of using calvarial bone grafts to enable implant placement in severely atrophic maxillae. MATERIAL AND METHODS: Seventeen patients with severe atrophic edentulous maxillae were reconstructed with autogenous calvarial bone grafts...
June 2017: Clinical Oral Implants Research
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