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Clinical Oral Implants Research

Daniel Bäumer, Otto Zuhr, Stephan Rebele, Markus Hürzeler
OBJECTIVES: Implant placement immediately after tooth extraction is often accompanied by resorption of surrounding tissues. A clinical technique was developed where the buccal portion of the root is retained to preserve the periodontal ligament and bundle bone. This technique is based on animal studies showing the potential to preserve the facial tissues utilizing this approach. The purpose of this study was to gain more insight regarding the safety of the technique with regard to biological and implant-related long-term complications and to observe the clinical appearance of the peri-implant tissues...
March 23, 2017: Clinical Oral Implants Research
Bo Wen, David Shafer, Peter Schleier, David Pendrys, Liisa Kuhn, Martin Freilich
OBJECTIVE: To evaluate the efficacy of various scaffold systems and a Ti scaffold-retaining device with and without non-glycosylated rhBMP-2 (BMP-2) for increasing the vertical alveolar bone growth in the intra-oral mini-pig model. METHODS: Forty-eight Straumann Bone Level implants with hydrophilic (SLActive) surfaces were partially embedded in mandibles of 12 adult mini-pigs with the shoulder of the implant located 3 mm above the bone crest. Twenty-four implants were placed in conjunction with BMP-2 (50 μg) incorporated within resorbable scaffolds...
March 9, 2017: Clinical Oral Implants Research
Jan-Willem G H Wetzels, Gert J Meijer, Ron Koole, Eddy M Adang, Matthias A W Merkx, Caroline M Speksnijder
OBJECTIVES: The aim of this study was to compare costs and clinical outcomes of two protocols for implant placement in edentulous oral cancer patients: implant placement during ablative surgery and postponed implant placement. MATERIAL AND METHODS: All edentulous patients who underwent curative tumor surgery between 2007 and 2009 at the Radboud university medical center (Radboudumc) and UMC Utrecht, both in the Netherlands, were included retrospectively. At the Radboudumc, 79 of 98 patients received implants during ablative surgery...
March 2, 2017: Clinical Oral Implants Research
Wenjuan Zhou, Sonja Kuderer, Zhonghao Liu, Christian Ulm, Xiaohui Rausch-Fan, Stefan Tangl
OBJECTIVES: The aim of this study was to perform a histomorphometric evaluation of the healing characteristics and jawbone remodeling processes in the peri-implant bone tissue of three commonly used implant surfaces, during the early weeks of osseointegration. MATERIAL AND METHODS: Dental implants with three different surfaces (anodically modified, hydroxyapatite (HA)-coated and machined) were inserted into the mandibular side-tooth region of twelve adult mini-pigs...
February 18, 2017: Clinical Oral Implants Research
Daniel S Thoma, Irena Sailer, Alexis Ioannidis, Marcel Zwahlen, Nikolay Makarov, Bjarni E Pjetursson
OBJECTIVES: The objective of this systematic review was to assess the 5-year and 10-year survival of resin-bonded fixed dental prostheses (RBBs) and to describe the incidence of technical and biological complications. MATERIALS AND METHODS: An electronic MEDLINE search complemented by manual searching was conducted to identify prospective and retrospective cohort studies and case series on RBBs with a mean follow-up time of at least 5 years. Patients had to have been examined clinically at the follow-up visit...
February 13, 2017: Clinical Oral Implants Research
Nazia Sultana, David W Bartlett, Mahmood Suleiman
OBJECTIVES: To assess the effect of implant angulation on the retention of two different attachment systems for implant-supported overdentures after a simulated fatigue period of 5.5 years. MATERIAL AND METHODS: Two test set-ups were constructed. A two-implant mandibular implant-supported overdenture design was simulated using acrylic resin blocks to support implant replicas (Model 1 and Model 2). The replicas were set up in the canine regions (22-mm inter-implant distance)...
February 13, 2017: Clinical Oral Implants Research
Daniel S Thoma, Hyun-Chang Lim, Vitor M Sapata, Sora R Yoon, Ronald E Jung, Ui-Won Jung
OBJECTIVES: Improvement in localized bone regeneration is needed to avoid the use of autogenous tissue. For that purpose, the use biologic mediators was proposed. The aim was to test whether or not one of two biologic mediators, recombinant human bone morphogenetic protein-2 (rhBMP-2) or recombinant platelet-derived growth factor (rhPDGF-BB), is superior to the other and to control groups for localized bone regeneration. MATERIALS AND METHODS: Four cylinders (height: 5 mm; diameter: 7 mm) were screwed on the parietal and frontal bones at the cranium in 12 rabbits...
February 6, 2017: Clinical Oral Implants Research
Mauro Merli, Francesco Bernardelli, Erica Giulianelli, Ivano Toselli, Giorgia Mariotti, Michele Nieri
OBJECTIVES: The objective was to evaluate the association between peri-implant bleeding on probing (BoP) and probing depth. Other factors regarding patients, implants, and sites were taken into consideration. MATERIAL AND METHODS: Consecutive adult patients with ≥1 dental implant were eligible. Two calibrated operators examined the patients. BoP was the outcome variable. The effects of patient, implant and site factors on BoP were assessed using a 3-level logistic model...
February 6, 2017: Clinical Oral Implants Research
Daniel S Thoma, Franz E Weber, Stefan P Bienz, Yanjun Ge, Christoph H F Hämmerle, Ronald E Jung
OBJECTIVES: To test whether or not chemical and/or physical modifications of polyethylene glycol (PEG) hydrogels influence degradation time, matrix/membrane stability, and integration into surrounding hard and soft tissues. MATERIAL AND METHODS: In 28 rabbits, six treatment modalities were randomly applied to six sites on the rabbit skull: a dense network PEG hydrogel (PEG HD), a medium-dense network PEG hydrogel (PEG MD), a medium-dense network PEG hydrogel modified with an RGD sequence (PEG MD/RGD), a medium-dense network PEG hydrogel modified with RGD with reduced carboxymethyl cellulose (PEG MD/RGD_LV), a loose network PEG hydrogel modified with RGD (PEG LD/RGD), and a collagen membrane (BG)...
January 22, 2017: Clinical Oral Implants Research
Md Arafat Kabir, Masaru Murata, Toshiyuki Akazawa, Kaoru Kusano, Katsuhisa Yamada, Manabu Ito
OBJECTIVES: Regenerating critical-size bone injury is a major problem that continues to inspire the design of new graft materials. Therefore, tissue engineering has become a novel approach for targeting bone regeneration applications. Human teeth are a rich source of stem cells, matrix, trace metal ions, and growth factors. A vital tooth-derived demineralized dentin matrix is acid-insoluble and composed of cross-linked collagen with growth factors. In this study, we recycled human non-functional tooth into a unique geometric dentin scaffold, entitled perforated root-demineralized dentin matrix (PR-DDM)...
January 17, 2017: Clinical Oral Implants Research
Umberto Demoner Ramos, Flavia Adelino Suaid, Ulf M E Wikesjö, Cristiano Susin, Mario Taba, Arthur Belém Novaes
OBJECTIVES: This study used a dog model to evaluate two antimicrobial protocols with or without guided bone regeneration (GBR) in the surgical reconstruction of peri-implantitis defects. MATERIAL AND METHODS: Eight beagle dogs subject to ligature-induced peri-implantitis were used. The animals either received antimicrobial photodynamic therapy or topical tetracycline hydrochloride combined with GBR or as stand-alone surgical interventions. Block biopsies of the defect sites for histological analysis were obtained at euthanasia, 12 weeks postsurgery...
January 5, 2017: Clinical Oral Implants Research
Sarah Amin, Hans Peter Weber, Matthew Finkelman, Khaled El Rafie, Yukio Kudara, Panos Papaspyridakos
PURPOSE: To test whether or not digital full-arch implant impressions with two different intra-oral scanners (CEREC Omnicam and True Definition) have the same accuracy as conventional ones. The hypothesis was that the splinted open-tray impressions would be more accurate than digital full-arch impressions. MATERIAL AND METHODS: A stone master cast representing an edentulous mandible using five internal connection implant analogs (Straumann Bone Level RC, Basel, Switzerland) was fabricated...
December 31, 2016: Clinical Oral Implants Research
Toshie Nagayasu-Tanaka, Takenori Nozaki, Koji Miki, Keigo Sawada, Masahiro Kitamura, Shinya Murakami
OBJECTIVES: The aim of this study was to examine the effect of basic fibroblast growth factor (FGF-2) on osseointegration of dental implants with low primary stability in a beagle dog model. MATERIALS AND METHODS: Customized titanium implants that were designed to have low contact with the existing bone were installed into the edentulous mandible of beagle dogs. To degrade the primary stability of the implants, the diameters of the bone sockets exceeded the implant diameters...
March 2017: Clinical Oral Implants Research
Andreas Stavropoulos, Niklaus P Lang, Anton Sculean, Jan Lindhe, Nikolaos Donos, Nikolaos Mardas
No abstract text is available yet for this article.
February 2017: Clinical Oral Implants Research
Simone F M Janner, Dieter D Bosshardt, David L Cochran, Vivianne Chappuis, Guy Huynh-Ba, Archie A Jones, Daniel Buser
OBJECTIVES: To evaluate the effect of a resorbable collagen membrane and autogenous bone chips combined with deproteinized bovine bone mineral (DBBM) on the healing of buccal dehiscence-type defects. MATERIAL AND METHODS: The second incisors and the first premolars were extracted in the maxilla of eight mongrels. Reduced diameter, bone-level implants were placed 5 weeks later. Standardized buccal dehiscence-type defects were created and grafted at implant surgery...
December 25, 2016: Clinical Oral Implants Research
Giovanni Serino, Hirohisa Sato, Patrick Holmes, Alberto Turri
OBJECTIVE: To evaluate the accuracy between the intra-surgical and the peri-apical radiographic measurements of bone loss at implant with peri-implantitis. MATERIALS AND METHODS: A total of 46 Brånemark implants in 24 patients with diagnosis of peri-implantitis were included in the study. The amount of peri-implant bone loss occurred at those implants was measured during peri-implant surgery and compared to the radiographic bone loss measured by three independent examiners...
December 23, 2016: Clinical Oral Implants Research
Nils Löfgren, Christel Larsson, Nikos Mattheos, Martin Janda
OBJECTIVE: Technical complications such as veneer fractures are more common in implant-supported than tooth-supported restorations. The underlying causes have not been fully identified. The aim of this study was to evaluate whether misfit between the restoration and the implant may affect the risk of veneer fractures. MATERIALS AND METHODS: Twenty standardized five-unit implant-supported metal-ceramic fixed dental prostheses (FDP)s were manufactured and fixed in acrylic blocks...
December 19, 2016: Clinical Oral Implants Research
Bastian Wessing, Istvan Urban, Eduardo Montero, Werner Zechner, Markus Hof, Javier Alández Chamorro, Nuria Alández Martin, Giovanni Polizzi, Silvio Meloni, Mariano Sanz
OBJECTIVE: To compare clinical performance of a new resorbable non-cross-linked collagen membrane, creos xenoprotect (CXP), with a reference membrane (BG) for guided bone regeneration at dehisced implant sites. MATERIALS AND METHODS: This randomized controlled clinical trial enrolled patients with expected dehiscence defects following implant placement to restore single teeth in the maxillary and mandibular esthetic zone and premolar area. Implants were placed using a two-stage surgical protocol with delayed loading...
December 18, 2016: Clinical Oral Implants Research
Shuzo Kitayama, Lok O Wong, Li Ma, Jia Hao, Shohei Kasugai, Niklaus P Lang, Nikos Mattheos
OBJECTIVES: Biphasic calcium phosphate (BCP) composed of 10% hydroxyapatite (HA) and 90% beta-tricalcium phosphate has been developed. Recently, a strontium hydroxyapatite-containing collagen membrane (Sr) was shown to stimulate early bone formation in rat calvarial defects at 4 weeks postoperatively, as compared with a cross-linked collagen membrane, for guided bone regeneration (GBR). The objective of this study was to evaluate these novel biomaterials for GBR in relation to a non-cross-linked collagen membrane (BG) and deproteinized bovine bone mineral (BO)...
December 2016: Clinical Oral Implants Research
Carlo Monaco, Edoardo Evangelisti, Roberto Scotti, Giuseppe Mignani, Giovanni Zucchelli
OBJECTIVE: This short communication reports on a novel digital technique designated - the "Fully Digital Technique (FDT)" - to take the impression of the peri-implant soft tissue and emergence profile with an intraoral scanner, digitally capturing both the three dimensional position of the implant platform and the coronal and gingival parts of the provisional retained restoration. MATERIALS AND METHODS: A first intraoral digital impression, which generated a standard triangulation language file (STL1), was taken using a standardized implant scanbody to detect the position of the implant...
December 2016: Clinical Oral Implants Research
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