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Clinical Oral Implants Research

Md Arafat Kabir, Masaru Murata, Toshiyuki Akazawa, Kaoru Kusano, Katsuhisa Yamada, Manabu Ito
OBJECTIVES: Regenerating critical-size bone injury is a major problem that continues to inspire the design of new graft materials. Therefore, tissue engineering has become a novel approach for targeting bone regeneration applications. Human teeth are a rich source of stem cells, matrix, trace metal ions, and growth factors. A vital tooth-derived demineralized dentin matrix is acid-insoluble and composed of cross-linked collagen with growth factors. In this study, we recycled human non-functional tooth into a unique geometric dentin scaffold, entitled perforated root-demineralized dentin matrix (PR-DDM)...
January 17, 2017: Clinical Oral Implants Research
Umberto Demoner Ramos, Flavia Adelino Suaid, Ulf M E Wikesjö, Cristiano Susin, Mario Taba, Arthur Belém Novaes
OBJECTIVES: This study used a dog model to evaluate two antimicrobial protocols with or without guided bone regeneration (GBR) in the surgical reconstruction of peri-implantitis defects. MATERIAL AND METHODS: Eight beagle dogs subject to ligature-induced peri-implantitis were used. The animals either received antimicrobial photodynamic therapy or topical tetracycline hydrochloride combined with GBR or as stand-alone surgical interventions. Block biopsies of the defect sites for histological analysis were obtained at euthanasia, 12 weeks postsurgery...
January 5, 2017: Clinical Oral Implants Research
Sarah Amin, Hans Peter Weber, Matthew Finkelman, Khaled El Rafie, Yukio Kudara, Panos Papaspyridakos
PURPOSE: To test whether or not digital full-arch implant impressions with two different intra-oral scanners (CEREC Omnicam and True Definition) have the same accuracy as conventional ones. The hypothesis was that the splinted open-tray impressions would be more accurate than digital full-arch impressions. MATERIAL AND METHODS: A stone master cast representing an edentulous mandible using five internal connection implant analogs (Straumann Bone Level RC, Basel, Switzerland) was fabricated...
December 31, 2016: Clinical Oral Implants Research
Simone F M Janner, Dieter D Bosshardt, David L Cochran, Vivianne Chappuis, Guy Huynh-Ba, Archie A Jones, Daniel Buser
OBJECTIVES: To evaluate the effect of a resorbable collagen membrane and autogenous bone chips combined with deproteinized bovine bone mineral (DBBM) on the healing of buccal dehiscence-type defects. MATERIAL AND METHODS: The second incisors and the first premolars were extracted in the maxilla of eight mongrels. Reduced diameter, bone-level implants were placed 5 weeks later. Standardized buccal dehiscence-type defects were created and grafted at implant surgery...
December 25, 2016: Clinical Oral Implants Research
Giovanni Serino, Hirohisa Sato, Patrick Holmes, Alberto Turri
OBJECTIVE: To evaluate the accuracy between the intra-surgical and the peri-apical radiographic measurements of bone loss at implant with peri-implantitis. MATERIALS AND METHODS: A total of 46 Brånemark implants in 24 patients with diagnosis of peri-implantitis were included in the study. The amount of peri-implant bone loss occurred at those implants was measured during peri-implant surgery and compared to the radiographic bone loss measured by three independent examiners...
December 23, 2016: Clinical Oral Implants Research
Nils Löfgren, Christel Larsson, Nikos Mattheos, Martin Janda
OBJECTIVE: Technical complications such as veneer fractures are more common in implant-supported than tooth-supported restorations. The underlying causes have not been fully identified. The aim of this study was to evaluate whether misfit between the restoration and the implant may affect the risk of veneer fractures. MATERIALS AND METHODS: Twenty standardized five-unit implant-supported metal-ceramic fixed dental prostheses (FDP)s were manufactured and fixed in acrylic blocks...
December 19, 2016: Clinical Oral Implants Research
Bastian Wessing, Istvan Urban, Eduardo Montero, Werner Zechner, Markus Hof, Javier Alández Chamorro, Nuria Alández Martin, Giovanni Polizzi, Silvio Meloni, Mariano Sanz
OBJECTIVE: To compare clinical performance of a new resorbable non-cross-linked collagen membrane, creos xenoprotect (CXP), with a reference membrane (BG) for guided bone regeneration at dehisced implant sites. MATERIALS AND METHODS: This randomized controlled clinical trial enrolled patients with expected dehiscence defects following implant placement to restore single teeth in the maxillary and mandibular esthetic zone and premolar area. Implants were placed using a two-stage surgical protocol with delayed loading...
December 18, 2016: Clinical Oral Implants Research
Arash Khojasteh, Saeed Reza Motamedian, Navid Sharifzadeh, Homayoun H Zadeh
OBJECTIVES: Clinicians commonly consider atrophic site topography as an important determinant in deciding the augmentation technique to utilize, as well as forecasting the likelihood of success. The purpose of this retrospective study was to examine the influence of initial atrophic posterior mandible morphology on the outcome of implants placed following augmentation. MATERIALS AND METHODS: A total of 52 patients contributed 71 edentulous sites, and 185 implants were placed with mean follow-up of 37...
November 2, 2016: Clinical Oral Implants Research
Shuzo Kitayama, Lok O Wong, Li Ma, Jia Hao, Shohei Kasugai, Niklaus P Lang, Nikos Mattheos
OBJECTIVES: Biphasic calcium phosphate (BCP) composed of 10% hydroxyapatite (HA) and 90% beta-tricalcium phosphate has been developed. Recently, a strontium hydroxyapatite-containing collagen membrane (Sr) was shown to stimulate early bone formation in rat calvarial defects at 4 weeks postoperatively, as compared with a cross-linked collagen membrane, for guided bone regeneration (GBR). The objective of this study was to evaluate these novel biomaterials for GBR in relation to a non-cross-linked collagen membrane (BG) and deproteinized bovine bone mineral (BO)...
December 2016: Clinical Oral Implants Research
Carlo Monaco, Edoardo Evangelisti, Roberto Scotti, Giuseppe Mignani, Giovanni Zucchelli
OBJECTIVE: This short communication reports on a novel digital technique designated - the "Fully Digital Technique (FDT)" - to take the impression of the peri-implant soft tissue and emergence profile with an intraoral scanner, digitally capturing both the three dimensional position of the implant platform and the coronal and gingival parts of the provisional retained restoration. MATERIALS AND METHODS: A first intraoral digital impression, which generated a standard triangulation language file (STL1), was taken using a standardized implant scanbody to detect the position of the implant...
December 2016: Clinical Oral Implants Research
Ji-Youn Hong, Min-Soo Kim, Hyun-Chang Lim, Jung-Seok Lee, Seong-Ho Choi, Ui-Won Jung
OBJECTIVES: The aim of the study was to elucidate the efficacy of bone regeneration at the early stage of healing in rabbit sinuses grafted with a biphasic calcium phosphate (BCP) carrier soaked in a high concentration of recombinant human bone morphogenetic protein-2 (rhBMP-2). MATERIALS AND METHODS: Both maxillary sinuses of eight male rabbits were used. The sinus on one side (assigned randomly) was grafted with BCP loaded with rhBMP-2 (1.5 mg/ml; test group) using a soaking method, while the other was grafted with saline-soaked BCP (control group)...
December 2016: Clinical Oral Implants Research
María Martín-Ares, Cristina Barona-Dorado, Blanca Guisado-Moya, Natalia Martínez-Rodríguez, Jorge Cortés-Bretón-Brinkmann, José Mª Martínez-González
OBJECTIVES: The aim of this study was to compare satisfaction with function and hygiene maintenance in completely edentulous elderly patients rehabilitated with implant-supported fixed prostheses, overdentures, and conventional prostheses. MATERIALS AND METHODS: A total of 150 geriatric patients were divided into three groups: Group 1 (CD) patients rehabilitated with complete dentures; Group 2 (FP) patients with implant-supported fixed prostheses; Group 3 (OD) patients with overdentures...
December 2016: Clinical Oral Implants Research
Gentaro Mori, Hodaka Sasaki, Yasushi Makabe, Masao Yoshinari, Yasutomo Yajima
OBJECTIVES: The peri-implant epithelium (PIE) plays an important role in the prevention against initial stage of inflammation. To minimize the risk of peri-implantitis, it is necessary to understand the biological characteristics of the PIE. The aim of this study was to investigate the characteristic gene expression profile of PIE as compared to junctional epithelium (JE) using laser microdissection and microarray analysis. METHODS: Left upper first molars of 4-week-old rat were extracted, and titanium alloy implants were placed...
December 2016: Clinical Oral Implants Research
Tim Joda, Urs Brägger
OBJECTIVES: The aim of this randomized controlled trial was to compare patient-centered outcomes during digital and conventional implant impressions. MATERIAL AND METHODS: In a crossover study design, intraoral scanning (IOS) [test] as well as classical polyether impressions [control] were both performed on 20 patients for single-tooth replacement with implant-supported crowns. The sequential distribution of either starting with the test or the control procedure was randomly selected...
December 2016: Clinical Oral Implants Research
Ratnadeep Patil, Laurens den Hartog, Anjali Dilbaghi, Bart de Jong, Wouter Kerdijk, Marco S Cune
OBJECTIVE: To evaluate the influence of abutment geometry on papillary fill in the esthetic zone in a delayed crown protocol. MATERIALS AND METHODS: Twenty-six subjects received two non-adjacent endosseous implants in the esthetic zone. Functional temporary crowns were installed 17-19 weeks later, using conventional (control) and curved (experimental) abutments. The abutments were randomized in each patient independently. Final crowns were cemented after 2 months (T0)...
December 2016: Clinical Oral Implants Research
Luigi Canullo, Roberto Cocchetto, Fabio Marinotti, David Peñarrocha Oltra, María Peñarrocha Diago, Ignazio Loi
BACKGROUND: Cement remnants were frequently associated with peri-implantitis. Recently, a shoulderless abutment was proposed, raising some concern about cement excess removal. AIM: To compare different cementation techniques for implant-supported restorations assessing the amount of cement remnants in the peri-implant sulcus. Additional aim was to compare the effect of these cementation techniques using two different abutment designs. MATERIAL & METHODS: Forty-six patients requiring double implant-supported restoration in the posterior maxilla were randomly divided in two groups according to the cementation modality: intraoral and extraoral...
December 2016: Clinical Oral Implants Research
O Salomó-Coll, J E Maté-Sánchez de Val, M P Ramírez-Fernández, M Satorres-Nieto, J Gargallo-Albiol, J L Calvo-Guirado
OBJECTIVE: The aim of this study was to evaluate the effects of topical applications of melatonin over implant surfaces placed immediately after extraction by means of histological and histomorphometric analysis of peri-implant tissues. MATERIAL AND METHODS: Six American foxhound dogs were used in the study; mandibular premolar distal roots were extracted. Thirty-six immediate conical implants were randomly assigned to the distal site on each site of the mandible in three groups: (Group CI) 12 titanium implants alone; (Group MI) 12 titanium implants supplemented with melatonin; and (Group DI) 12 titanium implants supplemented with vitamin D (DI)...
December 2016: Clinical Oral Implants Research
Michael Gahlert, Heinz Kniha, Dieter Weingart, Sabine Schild, Nils-Claudius Gellrich, Kai-Hendrik Bormann
INTRODUCTION: Dental implants have traditionally been made from titanium or its alloys, but recently full-ceramic implants have been developed with comparable osseointegration properties and functional strength properties to titanium. These ceramic implants may have advantages in certain patients and situations, for example, where esthetic outcomes are particularly important. OBJECTIVE: The objective of this investigation was to evaluate the performance of a newly developed full-ceramic ZrO2 monotype implant design (PURE Ceramic Implant; Institut Straumann AG, Basel, Switzerland) in single-tooth gaps in the maxilla and mandible...
December 2016: Clinical Oral Implants Research
Yvonne C M de Waal, Gerry M Raghoebar, Henny J A Meijer, Edwin G Winkel, Arie Jan van Winkelhoff
OBJECTIVES: Objective of this study was to identify prognostic indicators for the outcome of resective peri-implantitis treatment, by an analysis of the pooled data of two previously conducted randomized controlled trials. MATERIAL AND METHODS: Data of 74 patients with peri-implantitis (187 implants) who had received resective surgical treatment were available. Primary outcome variable was failure of peri-implantitis treatment after 12 months. Multilevel univariable and multiple logistic regression analyses were performed to evaluate the effect of various potentially prognostic indicators on the primary outcome...
December 2016: Clinical Oral Implants Research
Michael Korsch, Silke-Mareike Marten, Andreas Dötsch, Ruy Jáuregui, Dietmar H Pieper, Ursula Obst
BACKGROUND: Cementing dental restorations on implants poses the risk of undetected excess cement. Such cement remnants may favor the development of inflammation in the peri-implant tissue. The effect of excess cement on the bacterial community is not yet known. The aim of this study was to analyze the effect of two different dental cements on the composition of the microbial peri-implant community. METHODS: In a cohort of 38 patients, samples of the peri-implant tissue were taken with paper points from one implant per patient...
December 2016: Clinical Oral Implants Research
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