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Clinical Oral Implants Research

France Lambert, Miljana Bacevic, Pierre Layrolle, Peter Schüpbach, Pierre Drion, Eric Rompen
AIMS: The primary objective of this study was to compare the in vivo performance, namely in terms of quantity of newly formed bone and bone-to-material contact (osteoconductivity), of three hydroxyapatite-based biomaterials (HA) of different origins (natural or synthetic) or manufacturing process in a sinus lift model in rabbits. The secondary objective was to correlate the findings with the physical and topographical characteristics of the biomaterials. MATERIALS AND METHODS: Two bovine HA manufactured with different processes (bovine hydroxyapatites [BHA] and cuttlebone hydroxyapatite [CBHA]) and a synthetic hydroxyapatite (SHA) sintered at high temperature were characterised with scanning electronic microscopy (SEM) and the measurement of specific surface area (BET)...
October 22, 2016: Clinical Oral Implants Research
Sebastian Stefanski, Börje Svensson, Andreas Thor
PURPOSE: Various augmentation procedures involving the maxillary sinus, using bone substitutes or bone, have been used to enhance bone support for dental implants. The aim of this study was to retrospectively evaluate the status of implants in patients who had undergone a maxillary sinus lift and immediate implant placement without the addition of graft material. MATERIALS AND METHODS: Nineteen patients who had required bone augmentation of their maxillary sinus floor were evaluated in this study...
October 20, 2016: Clinical Oral Implants Research
Bruno R Chrcanovic, Jenö Kisch, Tomas Albrektsson, Ann Wennerberg
OBJECTIVES: To assess the survival of dental implants placed in sites of previously failed implants and to explore the possible factors that might affect the outcome of this reimplantation procedure. MATERIALS AND METHODS: Patients that had failed dental implants, which were replaced with the same implant type at the same site, were included. Descriptive statistics were used to describe the patients and implants; survival analysis was also performed. The effect of systemic, environmental, and local factors on the survival of the reoperated implants was evaluated...
October 14, 2016: Clinical Oral Implants Research
Mohammad D Al Amri, Sulieman S Al-Johany, Abdulaziz M Al Baker, Mohammad Q Al Rifaiy, Tariq S Abduljabbar, Abdulaziz A Al-Kheraif
OBJECTIVE: The aim of the present 36-month prospective split-mouth clinical trial was to investigate the peri-implant soft tissue changes and crestal bone loss (CBL) around delayed loaded platform-switched implants placed at crestal and subcrestal levels. MATERIAL AND METHODS: Twenty-three individuals with bilaterally missing either mandibular first or second molars were included. The test and control sites were defined as follows: (i) test sites: implants placed 2 mm below the alveolar crest (subcrestal); (ii) control sites: implants placed at bone level (crestal)...
October 14, 2016: Clinical Oral Implants Research
Daniel S Thoma, Jae-Kook Cha, Vitor M Sapata, Ronald E Jung, Juerg Hüsler, Ui-Won Jung
OBJECTIVES: To test whether or not one of two biological mediators (recombinant human bone morphogenetic protein-2 (rhBMP-2) and recombinant human platelet-derived growth factor (rhPDGF-BB)) is superior to the other and compared with control groups for bone regeneration around implants based on histomorphometrical outcome measures. MATERIALS AND METHODS: Box-type defects (10 × 5 × 5 mm) were prepared on the buccal sides of the left and right edentulous ridge in ten mongrel dogs...
October 10, 2016: Clinical Oral Implants Research
Eduardo Pinheiro Domingues, Rafael Fernandes Ribeiro, Martinho Campolina Rebello Horta, Flávio Ricardo Manzi, Maurício Greco Côsso, Elton Gonçalves Zenóbio
OBJECTIVE: Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS(®) ) or hydroxyapatite/tricalcium phosphate (STRAUMANN(®) BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy. MATERIAL AND METHODS: Seven patients received interposition grafts in the posterior mandible for implant rehabilitation. The computed tomography cone beam images were analysed with OsiriX Imaging Software 6...
October 4, 2016: Clinical Oral Implants Research
Diego Lops, Edoardo Stellini, Luca Sbricoli, Niccolò Cea, Eugenio Romeo, Eriberto Bressan
PURPOSE: The aim of the present clinical trial was to analyze, through spectrophotometric digital technology, the influence of the abutment material on the color of the peri-implant soft tissue in patients with thin gingival biotype. MATERIAL AND METHODS: Thirty-seven patients received an endosseous dental implant in the anterior maxilla. At time of each definitive prosthesis delivery, an all-ceramic crown has been tried on gold, titanium and zirconia abutment. Peri-implant soft-tissue color has been measured through a spectrophotometer after the insertion of each single abutment...
October 3, 2016: Clinical Oral Implants Research
Jeffrey J McCullough, Perry R Klokkevold
INTRODUCTION: Available literature suggests there is a transient drop in implant stability from approximately week 0 to week 3-4 as a result of peri-implant bone remodeling as it transitions from a primary, mechanical stability to a secondary, biological stability. Research investigating the influence of macro-thread design on this process is scant. AIM: The specific aim of this study was to evaluate the role of macro-thread design on implant stability in the early post-operative healing period using resonance frequency analysis (RFA)...
October 3, 2016: Clinical Oral Implants Research
Jamil Alayan, Cedryck Vaquette, Siamak Saifzadeh, Dietmar Hutmacher, Saso Ivanovski
OBJECTIVE: To assess the impact of a hydrophilic implant surface (SLActive(®) ) placed into augmented maxillary sinuses on bone-to-implant contact (BIC) and surrounding tissue composition when compared to a hydrophobic surface (SLA(®) ). MATERIAL AND METHODS: Four sheep underwent bilateral sinus augmentation. Each sinus received anorganic bovine bone mineral + autogenous bone (ABBM + AB). Sixteen implants were subsequently placed 12 weeks postgrafting with each sinus receiving a control (SLA(®) ) and test implant (SLActive(®) )...
September 29, 2016: Clinical Oral Implants Research
Damir Jelusic, Matthias L Zirk, Tim Fienitz, Darije Plancak, Ivan Puhar, Daniel Rothamel
OBJECTIVES: To compare a monophasic (100% ß-TCP) and a biphasic (60% HA and 40% ß-TCP) bone substitute material (BSM) regarding biocompatibility, osteoconductivity and implant stability using histological, radiological and resonance frequency analysis. MATERIAL AND METHODS: Sixty-seven sinus floor elevations were performed in 60 patients. One patient group (monophasic bone substitute [MBS], 30 patients, 32 sinuses) was augmented by the use of the monophasic material (Bioresorb(®) , Sybron Implant Solutions, Bremen, Germany), while the second group (biphasic bone substitute (BBS), 30 patients, 35 sinuses) received a biphasic material (Maxresorb(®) , Botiss Biomaterials, Berlin, Germany)...
September 29, 2016: Clinical Oral Implants Research
Anders Ekfeldt, Björn Fürst, Gunnar E Carlsson
OBJECTIVES: To evaluate the clinical outcome of custom-made zirconia abutments for implant-supported single-tooth restorations 10-11 years after insertion. MATERIAL AND METHODS: The study comprises a clinical examination of 23 patients with 30 restorations placed 10-11 years ago. Oral surgeons placed the implants. The prosthodontic treatment was provided at a prosthodontic specialist clinic. The restoration was either an all-ceramic crown for cementation or a screw-retained one-piece restoration with the veneering porcelain baked directly to the zirconia abutment...
September 24, 2016: Clinical Oral Implants Research
Sergio A Gehrke, María P Ramírez-Fernandez, José Manuel Granero Marín, Marcos Barbosa Salles, Massimo Del Fabbro, José Luis Calvo Guirado
OBJECTIVE: The aim of this study was to compare, through biomechanical and histological analysis, the aluminium (AlO2) and titanium dioxide (TiO2) microparticles for blasting during the sandblasting acid surface treatment in titanium dental implants using a rabbit tibia model. MATERIALS AND METHODS: Forty-eight commercially available titanium dental implants were divided into two test groups (n = 24 per group): implants with surface treated by AlO2 followed by acid etching as control group (Con group) and implants with surface treated by TiO2 followed by acid etching as test group (Test group)...
September 24, 2016: Clinical Oral Implants Research
Nadja Naenni, David Schneider, Ronald E Jung, Jürg Hüsler, Christoph H F Hämmerle, Daniel S Thoma
PURPOSE: To test whether or not one of two membranes is superior for peri-implant-guided bone regeneration in terms of clinical and histologic outcomes. MATERIAL AND METHODS: In 27 patients, 27 two-piece dental implants were placed in single-tooth gaps in the esthetic area. Buccal dehiscence and/or fenestration-type defects were regenerated using demineralized bovine bone mineral and randomly covered with either a resorbable membrane (RES) or a titanium-reinforced non-resorbable membrane (N-RES)...
September 23, 2016: Clinical Oral Implants Research
Frank Schwarz, Ilja Mihatovic, Shahram Ghanaati, Jürgen Becker
OBJECTIVES: To assess the clinical safety and performance of collagenated xenogeneic bone block (CXBB) for lateral alveolar ridge augmentation and two-stage implant placement. MATERIAL & METHODS: In ten patients exhibiting a single-tooth gap, the surgical procedure included the preparation of mucoperiosteal flaps, a rigid fixation of CXBB (Geistlich Bio-Graft(®) ) using an osteosynthesis screw, and contour augmentation. After 24 weeks of submerged healing, the primary endpoint was defined as the final ridge width sufficient to place an adequately dimensioned titanium implant at the respective sites...
September 23, 2016: Clinical Oral Implants Research
Noémie Staubli, Clemens Walter, Julia C Schmidt, Roland Weiger, Nicola U Zitzmann
OBJECTIVE: The aim of this systematic review was to assess the role of excess cement as risk indicator for peri-implant diseases. MATERIAL AND METHODS: A systematic literature search with the keywords peri-implant disease, peri-implant mucositis, peri-implantitis, excess cement, cemented, and screw-retained restorations was performed for articles published by June 2016 using MEDLINE and EMBASE electronic databases, complemented by hand searching. RESULTS: The included 26 publications referring to 21 study groups were published between 1999 and 2016 and comprised 945 subjects with 1010 cemented implant restorations in 10 prospective and eight retrospective studies and eight case reports/series with pronounced heterogeneity of the study designs...
September 19, 2016: Clinical Oral Implants Research
Ryan S B Lee, Stephen M Hamlet, Saso Ivanovski
OBJECTIVES: This study assessed the effect of titanium surface modification on macrophage phenotype polarization and osseous healing under diabetic conditions. MATERIALS AND METHODS: Critical-sized calvarial defects were created in healthy and streptozotocin-induced type I diabetic Sprague-Dawley rats. Titanium (Ti) discs with either large-grit sandblasted and acid-etched micro-rough (SLA) or hydrophilic-modified SLA (modSLA) surfaces were used to cover the healing defect for a period of up to 28 days...
September 17, 2016: Clinical Oral Implants Research
Moustafa A Elsyad, Mohammed Mahmoud Alokda, Ashraf Anwer Gebreel, Nelly Ibrahim Hammouda, Ahmed Ali Habib
OBJECTIVES: The aim of this study was to evaluate and compare the effect of two designs of implant-supported overdentures on peri-implant and posterior mandibular bone resorptions after 5 years of follow-up. MATERIALS AND METHODS: Twenty edentulous patients were randomly assigned into two equal groups: Group I (GI), patients received overdentures supported and retained by cantilevered bars on two canine implants and Group II (GII), patients received overdentures retained by straight bars on two canine implants and supported by two-first molar implants...
September 16, 2016: Clinical Oral Implants Research
Peter Rammelsberg, Justo Lorenzo-Bermejo, Stefanie Kappel
PURPOSE: The objective of this work was to evaluate the effect of prosthetic restoration on the survival of implants and on the incidence of implant-related complications. MATERIAL AND METHODS: From a prospectively documented clinical study, 1569 implants placed in 630 patients (mean age 59.56 years) were evaluated. Selection criteria were a conventional loading protocol, prosthetic restoration with at least one follow-up, and a minimum observation period of 9 months...
September 13, 2016: Clinical Oral Implants Research
Mariana Vilela Sônego, Marcelo Coelho Goiato, Daniela Micheline Dos Santos
OBJECTIVES: The aim of this study was to investigate the outcomes of the installation of two implant-supported overdentures until such treatment is complete. Although this treatment is well established in the literature, there are no studies comparing what happens to muscles and the quality of life (QoL) of patients during the treatment. METHODS: We selected 13 completely edentulous patients, according to inclusion and exclusion criteria, to rehabilitate with mandibular overdentures retained by two dental implants and a complete denture as antagonists...
September 11, 2016: Clinical Oral Implants Research
R Al-Kattan, M Retzepi, E Calciolari, N Donos
OBJECTIVES: To investigate the gene expression and molecular pathways implicated in the regulation of the osseous healing process following guided bone regeneration (GBR). MATERIAL AND METHODS: Six 6-month-old Wistar male rats were used. Standardized 5-mm critical size defects were created in the parietal bones of each animal and treated with an extracranial and intracranial ePTFE membrane, according to the GBR principle. Three animals were randomly sacrificed after 7 and 15 days of healing...
September 11, 2016: Clinical Oral Implants Research
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