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European Journal of Pediatric Surgery

Christoph Zoeller, Emi Yoshizawa, Mohammad V Sethi, Benno M Ure, Joachim F Kuebler
INTRODUCTION:  Negative pressure wound therapy (NPWT) is a novel tool to reduce surgical site infections (SSIs). Although SSIs are a common source of morbidity in infants undergoing laparotomy, the cost of the available NPWT devices has restricted its use to adult high-risk patients. We developed a low-cost method of NPWT in infants and analyzed its impact on the incidence of SSIs in infant patients. PATIENTS AND METHODS:  A consecutive series of infants (age ≤ 12 months) who underwent a clean-contaminated, contaminated, or dirty abdominal procedure via laparotomy from 08/2015 to 12/2016 were included...
June 19, 2018: European Journal of Pediatric Surgery
Stefanie Witt, Michaela Dellenmark-Blom, Jens Dingemann, Carmen Dingemann, Benno M Ure, Barbara Gomez, Monika Bullinger, Julia Quitmann
INTRODUCTION:  For parents of chronically ill children, the experiences of caregiving are challenged by increased demands and restrictions imposed by their child's disease. Therefore, this study aims to investigate the quality of life (QoL) in parents of children born with esophageal atresia (EA) and to explore associated factors. METHODS:  Parents of children (2-17 years) with EA recruited from two German pediatric hospitals participated in this cross-sectional study about QoL in EA...
June 19, 2018: European Journal of Pediatric Surgery
Robert J Vandewalle, Joseph C Easton, R Cartland Burns, Brian W Gray, Frederick J Rescorla
PURPOSE:  The purpose of this study is to describe a single institution's 11-year experience treating children with congenital pulmonary airway malformations (CPAMs) and pleuropulmonary blastoma (PPB). METHODS:  An institutional database was sampled for all patients aged 0 to 18 years from January 1, 2005, to December 31, 2015. Patients with a pathologic diagnosis of CPAM or PPB during this period were reviewed. RESULTS:  A total of 51 patients with a pathologic diagnosis of CPAM ( n  = 45; 88...
June 19, 2018: European Journal of Pediatric Surgery
Richard Sola, Yangyang R Yu, Tyler C Friske, Abdur R Jamal, Eric H Rosenfeld, Mark V Mazziotti, Shawn D St Peter, Sohail R Shah
INTRODUCTION:  The objective of this study was to evaluate the necessity of repeat imaging after an initial chest radiograph (CXR) following minimally invasive repair of pectus excavatum (MIRPE). MATERIALS AND METHODS:  A retrospective review was performed on patients who underwent MIRPE from January 2012 to July 2016 at two academic children's hospitals. Data collected included demographics, severity of pectus defect (Haller index [HI]), utilization of CXRs, outpatient follow-up, and clinical outcomes...
June 19, 2018: European Journal of Pediatric Surgery
Riccardo Coletta, Bashar Aldeiri, Antonino Morabito
AIM:  The aim of this study was to report our initial experience using spiral intestinal lengthening and tailoring (SILT) technique in selected cases of short bowel syndrome (SBS). MATERIALS AND METHODS:  We analyzed all cases of SBS underwent SILT in our unit since the introduction of the procedure in 2012. We retrospectively analyzed patients' demographics, pre- and postprocedure bowel length, surgical complications, and postoperative parenteral nutrition (PN) requirements...
June 19, 2018: European Journal of Pediatric Surgery
Chun Jing Ye, Jiang Wang, Yi Fan Yang, Zhen Shen, Gong Chen, Yan Lei Huang, Yi Jie Zheng, Rui Dong, Shan Zheng
OBJECTIVES:  Biliary atresia (BA) is a progressive inflammatory obstructive cholangiopathy in infants. High mobility group box 1 (HMGB1) is known to play an important role as a late mediator of inflammation. However, it is not clear whether HMGB1 levels are of clinical significance in patients with BA. The aim of this study was to determine correlations between serum HMGB1 levels and the clinicopathologic features of BA. MATERIALS AND METHODS:  Serum samples were collected from 19 infants with BA, 7 infants with anicteric choledochal cysts (CC) and normal liver function, and 8 healthy controls...
June 17, 2018: European Journal of Pediatric Surgery
Alexander Johannes Martinus Dingemans, Carlos Albert Reck-Burneo, Molly Fuchs, Alejandra Vilanova Sanchez, Victoria Alison Lane, Erin Hoover, Tassiana Maloof, Laura Weaver, Marc A Levitt, Richard J Wood
INTRODUCTION:  Previous research in children with Hirschsprung's disease (HD) and Down's syndrome (DS) has focused on colorectal outcomes. We set out to review urinary outcomes in this patient group. METHODS:  The medical records of all patients aged five years and older with HD were reviewed, and patients and caregivers filled out the Vancouver Symptom Score at intake, which is designed and validated to diagnose dysfunctional elimination syndrome. RESULTS:  A total of 104 patients with HD were included in this study...
June 17, 2018: European Journal of Pediatric Surgery
Amichai Ben Ari, Daniella Margalit, Raphael Udassin, Fortu Benarroch
INTRODUCTION:  Since hospitalization can be a traumatic event for children, many of them may suffer from a cluster of chronic psychological and emotional difficulties called Pediatric Medical Traumatic Stress (PMTS). Although PMTS causes considerable functional impairment and psychological distress and may decrease the children's compliance with post-surgical care, awareness of this condition is low and thus not enough effort is made to prevent it. The objective of this study is to assess prospectively the prevalence and characteristics of PMTS in school-age children following hospitalization in a general pediatric surgery ward and in their parents, which has not been documented before...
June 17, 2018: European Journal of Pediatric Surgery
Francesco Morini, Augusto Zani, Andrea Conforti, Ernest van Heurn, Simon Eaton, Prem Puri, Risto Rintala, Marija Lukac, Joachim F Kuebler, Florian Friedmacher, Rene Wijnen, Juan Antonio Tovar, Agostino Pierro, Pietro Bagolan
No abstract text is available yet for this article.
June 5, 2018: European Journal of Pediatric Surgery
G Lakshmi Prasad, Ajay Hegde, S Divya
INTRODUCTION:  Congenital dermal sinuses (CDS) are uncommon lesions. They are most often noted in lumbosacral region and may lead to meningitis or spinal abscess. Intramedullary spinal cord abscess (IMSCA) due to CDS is rare and often co-exists with an inclusion tumor such as dermoid/epidermoid cyst. MATERIALS AND METHODS:  Literature review was done to analyze all cases of pediatric IMSCA secondary to CDS by searching online databases starting from the oldest case reported...
June 1, 2018: European Journal of Pediatric Surgery
Fabio Bartoli, Valentina Pastore, Isabella Calè, Gabriella Aceto, Vittoria Campanella, Carla Lasalandra, Simona Magaldi, Francesco Niglio, Angela Basile, Raffaella Cocomazzi
PURPOSE:  The aim of the study was to investigate urinary levels of monocyte chemotactic protein-1 (MCP-1), epidermal growth factor (EGF), β-2-microglobulin (β2M), and FAS-ligand (FAS-L) in children with congenital anomalies of kidney and urinary tract (CAKUT) disease at risk of developing glomerular hyperfiltration syndrome. For this reason, we selected patients with multicystic kidney, renal agenesia and renal hypodysplasia, or underwent single nephrectomy. MATERIALS AND METHODS:  This prospective, multicentric study was conducted in collaboration between the Pediatric Surgery Unit in Foggia and the Pediatric Nephrology Unit in Bari, Italy...
May 4, 2018: European Journal of Pediatric Surgery
Rebecca Maria Rentea, Matthea J Rentea, Ben Biesterveld, Jennifer L Liedel, David M Gourlay
INTRODUCTION:  Prematurity, formula feeding, and early weaning strongly influence enterocyte differentiation. Intestinal alkaline phosphatase (IAP), an endogenous protein expressed in the intestines, is one enzyme that is affected by these factors. IAP supplementation decreases the severity of necrotizing enterocolitis (NEC) injury. We, therefore, hypothesized that prematurity predisposes this population to NEC due to IAP deficiency and investigated IAP expression and function in a neonatal rat model...
May 3, 2018: European Journal of Pediatric Surgery
Boris Wittekindt, Rolf Schloesser, Nora Doberschuetz, Emilia Salzmann-Manrique, Jasmin Grossmann, Bjoern Misselwitz, Udo Rolle
INTRODUCTION:  Congenital malformations are associated with substantial neonatal morbidity and mortality. Furthermore, only sparse data are available on the modalities of care provided to and the associated clinical outcomes in affected neonates. In this study, we focused on five malformations that require surgery during the neonatal period: duodenal stenosis and atresia (DA), gastroschisis (GA), omphalocele (OM), congenital diaphragmatic herniation (CDH), and esophageal atresia (EA)...
May 1, 2018: European Journal of Pediatric Surgery
Kathy Nga-Chu Lui, Paul Kwong Hang Tam, Elly Sau-Wai Ngan
Stem cells possess the ability of self-renewal and the potency to differentiate into multiple cell lineages. Somatic stem cells are present in adult tissues, but they usually exhibit limited differentiation capacity and life span. On the other hand, somatic cells from adult tissues can be reprogrammed into induced pluripotent stem cells (iPSCs) that retain a full differentiation capacity with unlimited self-renewal ability. Autologous origin of iPSCs makes them an ideal source of cells for regenerative medicine to replenish the missing or damaged cells in the patients...
June 2018: European Journal of Pediatric Surgery
Clare M Rees, Lucinda Tullie, Agostino Pierro, Edward Kiely, Joe I Curry, Kate Cross, Robert Yates, Simon Eaton, Paolo De Coppi
No abstract text is available yet for this article.
June 2018: European Journal of Pediatric Surgery
Flore Lesage, Sabiniano Roman, Savitree Pranpanus, Simona Ospitalieri, Silvia Zia, Julio Jimenez, Sheila MacNeil, Jaan Toelen, Jan Deprest
PURPOSE:  The reconstruction of congenital diaphragmatic hernia or other congenital soft tissue defects often requires implants. These can be either degradable or permanent, each having their advantages. Whatever type is being used, the host response induced by implants plays a crucial role to determine the outcome. Macrophages are pivotal during implant remodeling; they are plastic and acquire in response to environmental stimuli either an inflammatory status and mediate subsequent fibrosis or a regulatory status and facilitate functional remodeling...
June 2018: European Journal of Pediatric Surgery
Clare M Rees, Lucinda Tullie, Agostino Pierro, Edward Kiely, Joe I Curry, Kate Cross, Robert Yates, Simon Eaton, Paolo De Coppi
AIM:  The objective of the study is to describe management of exomphalos major and investigate the effect of congenital cardiac anomalies. METHODS:  A single-center retrospective review (with audit approval) was performed of neonates with exomphalos major (fascial defect ≥ 5cm ± liver herniation) between 2004 and 2014.Demographic and operative data were collected and outcomes compared between infants who had primary or staged closure. Data, median (range), were analyzed appropriately...
June 2018: European Journal of Pediatric Surgery
Layla Haller, Constance Barazzone-Argiroffo, Isabelle Vidal, Regula Corbelli, Mehrak Anooshiravani-Dumont, Anne Mornand
INTRODUCTION:  Rigid bronchoscopy was traditionally performed in the management of foreign-body aspiration (FBA). More recently, since development of a less invasive method, flexible bronchoscopy has been proposed in some centers for the management of FBA. For the past few years, we have applied a decisional algorithm, privileging flexible bronchoscopy for diagnosis and, in some cases, for extraction of foreign body (FB). Our aims are first to analyze our current management of FBA and second to examine the bronchoscopic findings and complications...
June 2018: European Journal of Pediatric Surgery
Francesco Fascetti-Leon, Hisham El Agami, Dalia Gobbi, Simon Clarke, Munther Haddad, Muhammad Choudhry
INTRODUCTION:  Impossibility to place a gastrostomy and failed gastroesophageal reflux surgery with unsafe swallow are the main indications to Feeding Jejunostomy (FJ) in children. The aim of this study is to quantify the incidence of complications associated with FJ. MATERIALS AND METHODS:  A retrospective review of patients who had surgically inserted FJ between January 2009 and August 2013 at our institution was conducted. Data were obtained from medical records, operative notes, and radiology database, focusing on complications...
June 2018: European Journal of Pediatric Surgery
Maristella Santi, Sebastiano A G Lava, Giacomo D Simonetti, Mario G Bianchetti, Gregorio P Milani
INTRODUCTION:  Existing information on acute idiopathic scrotal edema relies on small case series and textbooks. METHODS:  We searched reports with no date limits on acute idiopathic scrotal edema. RESULTS:  Thirty-seven studies were included. Sixteen case series addressed the prevalence of acute idiopathic scrotal edema among males with acute scrotum: among 3,403 cases, the diagnosis of acute idiopathic scrotal edema was made in 413 cases (12%)...
June 2018: European Journal of Pediatric Surgery
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