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Bio-medical Materials and Engineering

L Torrisi, C Scolaro
The physical properties of biocompatible titanium surfaces were modified using different techniques of surface treatment. Particularly the measurements of roughness and wetting ability were controlled using six different techniques: polishing, sandblasting, acid attack, laser ablation, ion implantation and nanoparticle deposition. The titanium surface wetting can be modified drastically depending on the used treatment to enhance the hydrophilic or the hydrophobic behaviour of the metallic biocompatible surface...
2017: Bio-medical Materials and Engineering
Kyoung-Tak Kang, Sung-Hwan Kim, Juhyun Son, Young Han Lee, Yong-Gon Koh
BACKGROUND: Computational models have been identified as efficient techniques in the clinical decision-making process. However, computational model was validated using published data in most previous studies, and the kinematic validation of such models still remains a challenge. Recently, studies using medical imaging have provided a more accurate visualization of knee joint kinematics. OBJECTIVE: The purpose of the present study was to perform kinematic validation for the subject-specific computational knee joint model by comparison with subject's medical imaging under identical laxity condition...
2017: Bio-medical Materials and Engineering
Remel Alingalan Salmingo, Tina Lercke Skytte, Marie Sand Traberg, Lars Pilgaard Mikkelsen, Kaj-Åge Henneberg, Christian Wong
Perthes' disease is a destructive hip joint disorder characterized by malformation of the femoral head in young children. While the morphological changes have been widely studied, the biomechanical effects of these changes still need to be further elucidated. The objective of this study was to develop a method to investigate the biomechanical alterations in Perthes' disease by finite element (FE) contact modeling using MRI. The MRI data of a unilateral Perthes' case was obtained to develop the three-dimensional FE model of the hip joint...
2017: Bio-medical Materials and Engineering
Clarisa Bozzini, Ginés Viscor, Juan C Ríos Kristjánsson, Emilio Picasso, Graciela Champin, Rosa M Alippi, Carlos E Bozzini
BACKGROUND: Physical activity plays a tremendous role in determining bone mechanical behavior, which is superimposed to gravidity. OBJECTIVE: Compare the geometric and material responses of the rat femur to a high intensity treadmill running training of a relatively short duration, as assessed by 3-point mechanical test. METHODS: Mature male rats (180.0 ± 30 g) were assigned (7 rats/group) to no exercise (NE) or treadmill exercise (EX)...
2017: Bio-medical Materials and Engineering
Andrea Němcová, Oto Janoušek, Martin Vítek, Ivo Provazník
The article deals with the testing of features for fatigue detection in electrooculography (EOG) records. An optimal methodology for EOG signal acquisition is described; the Biopac data acquisition system was used. EOG signals were being recorded while 10 volunteers were watching prepared scenes. Three scenes were created for this purpose - a rotating ball, a video of driving a car, and a cross. Recorded EOG signals were processed and 20 features were extracted. The features involved blinks, slow eye movement (SEM), rapid eye movement (REM), eye instability, magnitude, and periodicity...
2017: Bio-medical Materials and Engineering
S Uma Maheshwari, K Govindan, M Raja, A Raja, M B S Pravin, S Vasanth Kumar
Polyvinylalcohol (PVA) and Polyvinylpyrrolidone (PVP) blend incorporated with hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) is electrospun as nanofibrous composite scaffolds to act as suitable template for bone tissue engineering. Microscopic and spectroscopic characterizations confirm uniform integration of the crystalline calcium phosphate ceramics in the scaffolds. PVA-PVP blends are usually amorphous in nature and addition of phosphate ceramic particles specifically HAp elevates its crystalline behavior which is substantiated by XRD details...
2017: Bio-medical Materials and Engineering
Ningning Bai, Cui Tan, Qing Li, Zhongxian Xi
In this paper, a low-cost and multifunctional hydroxyapatite (HA)/pefloxacin (PFLX) drug eluting layer is coated on magnesium (Mg) alloy through a simple hydrothermal and dip process. The drug PFLX could provide effective prevention for bone infection and inflammation due to its broad-spectrum antibacterial property. And HA would promote the growth of new bone and further improve the biocompatibility of implants. Besides, both PFLX and HA exhibits excellent corrosion protection for Mg alloy substrate. This coating is of great value for improving the application of Mg alloy as biomaterials...
2017: Bio-medical Materials and Engineering
Ali Darroudi, Jaber Parchami, Morteza Kafaee Razavi, Ghazaleh Sarbisheie
OBJECTIVE: In this paper, an adaptive method based on error entropy criterion is presented in order to eliminate noise from Electroencephalogram (EEG) signals. METHOD: Conventionally, the Mean-Squared Error (MSE) criterion is the dominant criterion deployed in the adaptive filters for this purpose. By deploying MSE, only second-order moment of the error distribution is optimized, which is not adequate for the noisy EEG signal in which the contaminating noises are typically non-Gaussian...
2017: Bio-medical Materials and Engineering
Ke-Ju Ju, Ling-Ling Zhong, Xiao-Yu Ni, Lei Xia, Liu-Jun Xue, Guan-Liang Cheng
OBJECTIVE: This study aims to explore the application prospect of low oxygen dead space ventilation (LODSV) in evaluating vasomotor reactivity (VMR) by comparison between LODSV and breath-holding test (BHT). METHODS: Outpatient or inpatient patients who underwent transcranial Doppler sonography (TCD) were enrolled into this study. These patients successively underwent BHT and LODSV. The cooperation degree, tolerance conditions and adverse reactions in patients were recorded, and VMR was calculated, compared and analyzed...
2017: Bio-medical Materials and Engineering
Liqing Deng, Donghai Li, Zhouyuan Yang, Xiaowei Xie, Pengde Kang
Hydroxyapatite (HA) is a representative bone repairing biomaterial for its similar composition to human bones and teeth. However, pure HA is limited in application for some unwanted characteristic, such as it is brickle and weakness in degradation. In this study, we modified HA by doping magnesium (Mg) to the material and studied its property in vitro. Besides, we also evaluated the calvarial defect repair effect using MgHA combined with rhBMP-2 in goat model. According to our outcomes, HA composited Mg made the scaffold smooth and the pore regular...
2017: Bio-medical Materials and Engineering
Tsuyoshi Ota, Soichiro Itoh, Kimihiro Yamashita
BACKGROUND: There are few reports of Low-intensity pulsed ultrasound (LIPUS) treatment for fresh forearm fractures in children. OBJECTIVES: LIPUS stimulation was applied after surgery of forearm fractures in children and the efficacy and safety of combination therapy of LIPUS treatment were evaluated. PATIENTS AND METHODS: Children with both radius and ulna fracture, twenty-five diaphysis (mid-R&U) and nineteen metaphysis (dist-R&U) fractures, were treated with intramedullary nailing followed by cast and splint mobilization...
2017: Bio-medical Materials and Engineering
Yuma Suzuki, Tetsuhide Shimizu, Ming Yang
BACKGROUND: The quantitative evaluation of the biomolecules transport with multi-physics in nano/micro scale is demanded in order to optimize the design of microfluidics device for the biomolecules detection with high detection sensitivity and rapid diagnosis. OBJECTIVE: This paper aimed to investigate the effectivity of the computational simulation using the numerical model of the biomolecules transport with multi-physics near a microchannel surface on the development of biomolecules-detection devices...
2017: Bio-medical Materials and Engineering
Agnieszka Gołąb, Małgorzata Kulesa-Mrowiecka, Marek Gołąb
BACKGROUND: Nowadays we observe growing popularity of kinesiotaping as a supportive method in physiotherapy. In documents available on kinesiotaping we can find that mechanical properties of tapes are similar to the ones of a human skin, but usually there is hardly any numerical data characterizing these properties. OBJECTIVE: Therefore, testing and comparing physical properties of commercially available kinesiotapes seems to be important. METHODS: Physical properties of five commercially available kinesiotapes were examined...
2017: Bio-medical Materials and Engineering
Fei Wang, Jian Zhang, Rong Wang, Yongquan Gu, Jianxin Li, Cong Wang
BACKGROUND: Morbidity and mortality of cardiovascular diseases are increasing in recent years. To solve these problems, vascular transplantation has become a common approach. Decellularization has been a hot spot of tissue engineering to prepare vessel substitutes for vascular transplantation. However, there is no established canonical protocol for decellularization thus far. OBJECTIVE: To further understand the decellularization effect of decellularization protocols and the causal relationship between decellularization and mechanical properties...
2017: Bio-medical Materials and Engineering
Hsueh-Chuan Hsu, Shih-Ching Wu, Shih-Kuang Hsu, Yi-Hang Liao, Wen-Fu Ho
BACKGROUND: As titanium (Ti) alloys are bioinert, various chemically-modified Ti surface has been developed to promote bioactivity and bone ingrowth. OBJECTIVE: In this study, various post treatments (water aging, hydrothermal, and heat treatments) were applied to NaOH-treated Ti-5Si to improve its bioactivity. METHODS: The bioactivity of surface-modified Ti-5Si was access by using the apatite formation ability of Ti-5Si surfaces soaking in a simulated body fluid (SBF)...
2017: Bio-medical Materials and Engineering
Mahboobeh Mahmoodi, Mohammad Zamanifard, Mina Safarzadeh, Shahin Bonakdar
BACKGROUND: Polytetrafluoroethylene (PTFE) is poorly biocompatible due to its low surface energy and hydrophobicity, which cause weak cell attachment and proliferation and complicate its use in implants. OBJECTIVE: NH3 plasma was used for surface modification and binding of amine groups on the PTFE surface. Collagen was immobilized on the plasma-treated PTFE in order to enable it to support enhanced cell adhesion and growth. METHODS: PTFE was exposed to NH3 plasma and collagen was immobilized on the NH3 plasma-treated surface...
2017: Bio-medical Materials and Engineering
Borhan Beigzadeh, Seyed Alireza Mirmohammadi, Majid Reza Ayatollahi
BACKGROUND: Stenting has been proposed as an effective treatment to restore blood flow in obstructed arteries by plaques. Although several modified designs for stents have been suggested, most designs have the risk of disturbing blood flow. OBJECTIVE: The main objective is to propose a stent design to attain a uniform lumen section after stent deployment. METHODS: Mechanical response of five different designs of J & J Palmaz-Schatz stent with the presence of plaque and artery are investigated; four stents have variable strut thickness of different magnitudes and the rest one is a uniform-strut-thickness stent...
2017: Bio-medical Materials and Engineering
Chia-Ling Ko, Hui-Yu Wu, Yu-Sheng Lin, Chun-Hui Yang, Jian-Chih Chen, Wen-Cheng Chen
BACKGROUND: A biodegradable porous particle for the controlled biofactor delivery which assembly of pores in scaffolds can improve the permeation and diffusion of drugs or growth factors. OBJECTIVE: Porous-spheres in millimeter scale were prepared by mixing sodium alginate and gelatin interpenetrating networks with cross-linkers; interconnected open pores were fabricated through solvent casting and particulate leaching. METHODS: Morphological characteristics, degradation, and bovine serum albumin (BSA) release rates of the porous-spheres immersed in three different solutions, namely, deionized distilled water, simulated body fluid (SBF), and phosphate-buffered saline (PBS), were detected...
2017: Bio-medical Materials and Engineering
Panagiotis Mallis, Efstathios Michalopoulos, Constantine Dimitriou, Nikolaos Kostomitsopoulos, Catherine Stavropoulos-Giokas
BACKGROUND: Each year, more than 800,000 vascular and cardiac surgeries are performed therefore, there is a great need for suitable material for bioprosthetic operations. Porcine pericardium is a double-walled sac that covers the heart and can be used in vascular and cardiac thoracic surgery. OBJECTIVE: The aim of the present study was to evaluate the decellularization process and biomechanical properties in porcine pericardial tissue after the decellularization treatment...
2017: Bio-medical Materials and Engineering
Shyh-Chour Huang
The knee joint is one of the more important parts in the human body. Its continuous involvement in the human movement makes it prone to breakage. Due to small contact area, the contact pressure is quite large in this joint. Therefore, the understanding of stresses behavior in knee joint contact is a necessity. In this study, we investigated the stresses behavior in the tibial insert by FEA. A two-dimensional FE model representing the knee joint contact mechanism was created. In the elastic simulation, the contact pressure dropped by 0...
2017: Bio-medical Materials and Engineering
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