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Acta Cirúrgica Brasileira

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[This corrects the article doi: 10.1590/s0102-865020170120000006].
February 2018: Acta Cirúrgica Brasileira
Paulo Henrique Muleta Andrade, Luciane Canderolo Portugal, Eric Schmidt Rondon, Monica Cristina Toffoli Kadri, Maria de Fátima Cepa Matos
PURPOSE: To analyzed the healing effect of the powdered shell of the Megalobulimus lopesi snail on wounds of diabetic rats, since in non-diabetic rats the powdered shell presented healing potential. METHODS: Seventy-two Wistar rats (Rattus norvegicus albinus) were divided into three groups: Control group (GC.diab), no therapeutic intervention on the wound; Vehicle's Control group, topical via, in diabetic rats (GCvt.diab): Powder Shell Group (PC) applied topically (GPCvt...
February 2018: Acta Cirúrgica Brasileira
Ye Li, Haifeng Hu, Jingchen Liu, Qingsan Zhu, Rui Gu
PURPOSE: To investigate the effects of aquaporin 4 (AQP4) and inward rectifier potassium channel 4.1 (Kir4.1) on medullospinal edema after treatment with methylprednisolone (MP) to suppress acute spinal cord injury (ASCI) in rats. METHODS: Sprague Dawley rats were randomly divided into control, sham, ASCI, and MP-treated ASCI groups. After the induction of ASCI, we injected 30 mg/kg MP via the tail vein at various time points. The Tarlov scoring method was applied to evaluate neurological symptoms, and the wet-dry weights method was applied to measure the water content of the spinal cord...
February 2018: Acta Cirúrgica Brasileira
Nurullah Bülbüller, Barış Rafet Karakaş, Hülya Tosun Yıldırım, Muhittin Yaprak, Veli Vural, Sadıka Halide Akbaş, Arzu Karaveli, Cem Sezer
PURPOSE: To evaluate the effect of a new cross-linked hyaluronan (NCHA) gel on healing of the staple line in an experimental sleeve gastrectomy. METHODS: Eighteen rats were randomly divided into three groups. The control group (n = 6) received no medication. In the saline group (n = 6) and NCHA gel group (n = 6), saline and NCHA gel were respectively administered onto the staple line and intraperitoneally into the abdominal cavity after the standard stapling procedure...
February 2018: Acta Cirúrgica Brasileira
Samanta Sarmento da Silva, Guilherme Eckert Peterson, Sérgio Luis Amantéa, Patrícia Miorelli, Jane Maria Ulbrich, Eliane Roesch, Paulo Roberto Sanches, Jose Carlos Fraga
PURPOSE: To evaluate the concentration of transforming growth factor beta 1 (TGFB1) levels in a rat pleural effusion obtained by inoculation of intrapleural bacteria or turpentine through thoracentesis. METHODS: Thirty-Nine Wistar rats were divided into three groups: Staphylococcus aureus (SA, n = 17); Streptococcus pneumoniae (SP, n = 12); and turpentine (control, n = 10). Pleural fluid was collected through ultrasound-guided thoracentesis 12 h, 24 h, and 36 h after instillation of bacteria or turpentine...
February 2018: Acta Cirúrgica Brasileira
Mariana Barbosa Dias Campelo, Joelita de Alencar Fonseca Santos, Antonio Luiz Martins Maia Filho, Daniel Cabral Leão Ferreira, Luciana Barros Sant'Anna, Rauirys Alencar de Oliveira, Leonardo Fonseca Maia, Emilia Ângela Loschiavo Arisawa
PURPOSE: To evaluate the efficacy of the application of the human amniotic membrane (HAM) on the inflammatory process, fibroblast proliferation, formation of collagenand reduction of skin wound areas in rats. METHODS: Thirty six rats were submitted to a surgical injury induction and divided into two groups (n = 18): group C (control) and T (treated with the HAM). The macroscopic evolution in the wound area and the histological characteristics of the skin samples were evaluated...
February 2018: Acta Cirúrgica Brasileira
Ceren Canbey Goret, Nuri Emrah Goret, Asli Kiraz, Omer Faruk Ozkan, Muammer Karaayvaz
PURPOSE: To investigate the effects of pycnogenol on peritoneal adhesions and additionally to investigate the immunohistochemical effects of free oxygen radicals and reactive lymph nodes detected in the adhesive tissue that was sampled surrounding the cecum on intra-abdominal adhesions. METHODS: Twenty-seven Wistar Albino rats were divided into three groups. In group 1 (sham), laparotomy was performed and stitched up. In group 2 (control), after laparotomy was performed, punctate hemorrhage was induced by cecal abrasion in the cecum and each rat was intraperitoneally administered 2 cc of saline...
February 2018: Acta Cirúrgica Brasileira
Ercan Yuvanc, Devrim Tuglu, Tunc Ozan, Ucler Kisa, Mahi Balci, Ertan Batislam, Erdal Yilmaz
PURPOSE: To investigate the biochemical, histopathologic, and spermatogenetic changes in the detorsionated testicle after experimental torsion and to study the antioxidant effects of pheniramine maleate and nebivolol. METHODS: Twenty-four Sprague-Dawley male rats were divided into 4 groups: Group 1: Sham; Group 2: Torsion/Detorsion (T/D); Group 3: T/D + Pheniramine maleate (PM); Group 4: T/D + Nebivolol (NB) group. Paroxanase (PON), total antioxidant status (TAS), total oxidant status (TOS), and oxidative stres index (OSI) were measured, and spermatogenetic and histopathologic evaluation was performed in tissue and blood samples...
February 2018: Acta Cirúrgica Brasileira
Wei Wang, Qi Wang, Wanyou Yu, Lianhua Chen, Zhong Li
PURPOSE: To observe the efficacy of phosphocreatine pre-administration (PCr-PA) on X-linked inhibitor of apoptosis protein (XIAP), the second mitochondia-derived activator of caspase (Smac) and apoptosis in the ischemic penumbra of rats with focal cerebral ischemia-reperfusion injury (CIRI). METHODS: A total of 60 healthy male Sprague Dawley (SD) rats were randomly divided into three groups (n=20): group A (the sham operation group), group B <intraperitoneally injected with 20 mg/kg (10 mg/ml) of saline before preparing the ischemia-reperfusion (IR) model>, and group C <intraperitoneally injected with 20 mg/kg (10 mg/ml) of PCr immediately before preparing the IR model>...
February 2018: Acta Cirúrgica Brasileira
Orhan Gozeneli, Faik Tatli, Ali Erdal Gunes, Muhammed Emin Guldur, Abdullah Taskin, Osman Bardakci, Mehmet Yilmaz
PURPOSE: To investigate thymoquinone, curcumin and a combination of these two drugs were effective or not at the growth of liver. METHODS: Forty female Wistar-Albino rats distributed into five groups of eight rats each, control, thymoquinone, curcumin, and thymoquinone/curcumin groups. Pathological specimens were studied using the Ki-67 Proliferation Index(PI); and arginase(Arg), tissue plasminogen activator(tPA), ceruloplasmin(Cer) and nitric oxide(NO) were studied in biochemical analysis...
February 2018: Acta Cirúrgica Brasileira
Maria de Lourdes Pessole Biondo-Simões, Marian Hanae Oda, Suzane Pasqual, Rogério Ribeiro Robes
PURPOSE: To compare polyglactin 910 and simple catgut sutures for the incidence of intraperitoneal adhesions. METHODS: Twenty female Wistar rats were placed into two groups. Group 1 received ischemic sutures and Group 2 received polyglactin 910. Five sutures inductive of adhesions in each rat were made. After 14 days, the rats were euthanized with an assessment of the presence of adhesions, the number of sutures involved and classification according to the Granat et al...
February 2018: Acta Cirúrgica Brasileira
Oscar Estupinam, André Lacerda de Abreu Oliveira, Fernanda Antunes, Manoel Galvão, Henrique Phillips, Jussara Peters Scheffer, Marcelo Rios, Ricardo Zorron
PURPOSE: To perform technically the laparoscopic sleeve gastrectomy (LSG) using a unique Intragastric Single Port (IGSG) in animal swine model, evidencing an effective and safe procedure, optimizing the conventional technique. METHODS: IGSG was performed in 4 minipigs, using a percutaneous intragastric single port located in the pre-pyloric region. The gastric stapling of the greater curvature started from the pre-pyloric region towards the angle of His by Endo GIA™ system and the specimen was removed through the single port...
January 2018: Acta Cirúrgica Brasileira
José Arnaldo Shiomi da Cruz, André Filipe Miranda, Lucas Evangelista da Costa, Rafael Ulysses de Azevedo, Sabrina Thalita Dos Reis, Miguel Srougi, Carlo Camargo Passerotti
PURPOSE: To evaluate whether the use of the physical surgical simulator may benefit the development of laparoscopic skills. METHODS: Ten medical students were divided into two groups: the first one performed ten weekly training sessions with a physical surgical simulator - ETX A2 LAP and, afterwards, one laparoscopic cholecystectomy in a porcine model, while the second group performed only a laparoscopic cholecystectomy. Both groups were compared regarding bleeding, total surgical time, time to perform each surgical step and qualitative parameters, based on a previously validated tool...
January 2018: Acta Cirúrgica Brasileira
Francisco Ferreira Filho, Luiz Gonzaga de Moura Júnior, Hermano Alexandre Lima Rocha, Sabrina Gabriele Maia Oliveira Rocha, Lucas Fortes Portela Ferreira, Amanda Fortes Portela Ferreira
PURPOSE: To develop and test a model of teaching by means of an abdominal cavity simulator. METHODS: This study had two stages: development of a teaching model and an experimental prospective study that aimed to evaluate the residents' competence. The participants were divided into 3 groups: first-year resident, second-year resident, and senior surgeon. The two groups of resident physicians received training in the simulator, under instructor supervision for skill acquisition, according to the model proposed in first stage...
January 2018: Acta Cirúrgica Brasileira
Taciana Freitas Agrelli, Marisa de Carvalho Borges, Fernanda Maria Rodrigues da Cunha, Élida Mara Carneiro da Silva, Júverson Alves Terra Júnior, Eduardo Crema
PURPOSE: To compare pulmonary and nutritional parameters before and after inspiratory muscle training (IMT) and enteral feeding support in patients with esophageal disease undergoing preoperative outpatient follow-up. METHODS: Thirty patients with a mean age of 55.83 years, 16 men and 14 women, were included. Pulmonary assessment consisted of the measurement of MIP, MEP, and spirometry. Anthropometric measurements and laboratory tests were performed for nutritional assessment...
January 2018: Acta Cirúrgica Brasileira
Gracilene Pinheiro Silva, Daniele Cristina Cataneo, Antonio Jose Maria Cataneo
PURPOSE: To evaluate the most used approach to treat traumatic diaphragmatic ruptures, and in which one the requirement to assess the second cavity is more frequent. METHODS: Systematic review, observational studies. Outcomes: moment of approach, most commonly via addressed and the requirement to open the other cavity. Bases searched: Lilacs, Pubmed, Embase, and Web of Science. Statistical analysis: StatsDirect 3.0.121 software. RESULTS: Sixty eight studies (2023 participants) were included...
January 2018: Acta Cirúrgica Brasileira
Liwei Pang, Jing Kong, Yuwen Wang, Yan Zhang
PURPOSE: To compare the safety, feasibility, and short-term clinical benefits of laparoscopic pylorus-preserving pancreaticoduodenectomy (L-PPPD) to open pylorus-preserving pancreaticoduodenectomy (O-PPPD) through retrospective matched cases. METHODS: Web of Science, Cochrane, PubMed, CNKI were searched systematically identify studies published between January and December 2017 comparing L-PPPD to O-PPPD. The meta-analysis was performed by using Review Manager 5...
January 2018: Acta Cirúrgica Brasileira
Maria Salete Sandini Linden, Marcos Eugênio de Bittencourt, João Paulo De Carli, Daniela Cristina Miyagaki, Pâmela Letícia Dos Santos, Luiz Renato Paranhos, Francisco Carlos Groppo, Juliana Cama Ramacciato
PURPOSE: To evaluate the influence of subcutaneous injection nicotine in osseointegration process on different implant surfaces. METHODS: Twenty-two male rabbits were distributed into two groups according to the subcutaneous injections: (1) nicotine 3 mg/day/kg and (2) 0.9 % NaCI 3 mL/day/kg, three times a day; subgroups were then designated-machined and anodized implants were placed in the right and left tibia bones, respectively. The animals were submitted euthanasia after periods of eight weeks to determine nicotine and cotinine levels, alkaline phosphatase and biomechanical analysis...
January 2018: Acta Cirúrgica Brasileira
Jianjun Ren, Changfa Li, Yan Liu, Haitao Liu, Zhenming Dong
PURPOSE: To investigate the influence of dexmedetomidine on myocardial ischemia-reperfusion injury (IRI) in rabbits. METHODS: Twenty-four New Zealand white rabbits were randomly divided into two equal-sized groups: IRI group (group IR) and dexmedetomidine group (group D). Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), left ventricular systolic pressure (LVSP), left ventricular end-diastolic pressure (LVEDP), left ventricular diastolic pressure (LVDP), +dp/dtmax, -dp/dtmax, and t-dp/dtmax were recorded and calculated at the following time points: before (T0) and after (T1) dexmedetomidine infusion, after 30-min ischemia (T2), and after 120-min reperfusion (T3)...
January 2018: Acta Cirúrgica Brasileira
Luiz Eduardo Moreira Teixeira, Bruno Jannotti Pádua, André Moreira Castilho, Ivana Duval de Araújo, Marco Antônio Percope de Andrade, Valbert Nascimento Cardoso, Simone Odília Diniz, Jefferson Soares Leal, Isabella Kuniko Takenaka
PURPOSE: To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime. METHODS: Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws...
January 2018: Acta Cirúrgica Brasileira
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