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Acta Cirúrgica Brasileira

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https://www.readbyqxmd.com/read/27828605/critical-analysis-and-systematization-of-rat-pancreatectomy-terminology
#1
José Marcus Raso Eulálio, Assad Charbel Chequer Bon-Habib, Daiane de Oliveira Soares, Paulo Guilherme Antunes Corrêa, Giovana Penna Firme Pineschi, Victor Senna Diniz, José Eduardo Ferreira Manso, Alberto Schanaider
PURPOSE: To critically analyze and standardize the rat pancreatectomy nomenclature variants. METHODS: It was performed a review of indexed manuscripts in PUBMED from 01/01/1945 to 31/12/2015 with the combined keywords "rat pancreatectomy" and "rat pancreas resection". The following parameters was considered: A. Frequency of publications; B. Purpose of the pancreatectomy in each article; C. Bibliographic references; D. Nomenclature of techniques according to the pancreatic parenchyma resection percentage...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828604/publication-rate-of-abstracts-presented-in-a-brazilian-experimental-surgery-congress
#2
Marcus Vinicius Henriques Brito, Nara Macedo Botelho, Edson Yuzur Yasojima, Renan Kleber Costa Teixeira, Vitor Nagai Yamaki, Daniel Haber Feijó, Igor Nagai Yamaki, Carolina Ribeiro Mainardi
PURPOSE: To verify the publication rate of the abstracts presented at the XII Brazilian Congress of Experimental Surgery. METHODS: We performed a cross-sectional study that evaluated if the abstracts accepted for presentation at the XII Brazilian Congress of Experimental Surgery were published in periodics. The information was acquired using the Scielo, Medline / Pubmed, LILACS and Google Scholar databases. RESULTS: From all the abstracts presented, only 77 (40...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828603/vertical-gastrectomy-in-overweight-and-non-overweight-rats
#3
Fernando Issamu Tabushi, Melissa Spena Stueber, Benur Polonio, João Carlos Domingues Repka, Sérgio Ossamu Ioshii, Paulo Afonso Nunes Nassif
PURPOSE: To compare the two lines suture (total and seromuscular) after partial gastrectomy in normal and overweight rats. METHODS: Forty Wistar rats were distributed in two groups. Group A received normal diet; group B, normal diet and supplementation with saccharose in the water. When group B progressed to a statistically greater weight than the animals of group A, the experiment (sleeve-like gastrectomy) was conducted with gastrorraphy in two sutures lines (total and seromuscular)...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828602/ventral-abdominal-wall-defect-correction-in-rats-with-contaminated-meshes
#4
Paola Zarur Varella, Nicolau Gregori Czeczko, Manoel Alberto Prestes, Alexandre Eduardo Augustin Czeczko, Marília da Cruz Fagundes, Roberta Dombroski Petisco
PURPOSE: To investigate whether there is a difference between Marlex(r) and Dynamesh PP-light Marlex(r) meshes, in the abdominal wall defect correction, on rats in contaminated surgical site. METHODS: Twenty-eight Wistar rats were divided into two groups of 14, and four subgroups of seven animals. All subgroups underwent similar surgical procedure. One group received the mesh Marlex(r) and the other Dynamesh PP-light(r) for correction of the defect. Before implanting, the meshes went through a contamination process, on which was used standard solution containing 10 UFC of Escherichia coli...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828601/remote-ischemic-preconditioning-and-tacrolimus-in-the-fetal-small-bowel-transplant-in-mice
#5
Ricardo José Morello, Marcia Kiyomi Koike, Marcos de Souza Abrahão, Karen Ruggeri Saad, Paulo Fernandes Saad, Edna Frasson de Souza Montero
PURPOSE: To evaluate the effect of remote ischemic preconditioning (IPC-R) in the fetal small bowel transplantation model. METHODS: Two groups were constituted: The Isogenic transplant (ISO, C57BL/6 mice, n=24) and the allogenic transplant (ALO, BALB/c mice, n=24). In each group, the animals were distributed with and without IPC-R. It was obtained the following subgroups: Tx, IPC-R, Fk, IPC-Fk, in both strains. Intestinal grafts were stained with hematoxylin and eosin and immunohistochemically...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828600/is-the-combination-of-fat-grafts-and-platelet-rich-plasma-effective-in-rats
#6
Alexandre Roriz Blumenschein, Ruffo Freitas-Junior, Marise Amaral Rebouças Moreira, Maria-Auxiliadora Paula Carneiro Cysneiros, Roseana Netto Pereira, Andrea Thomazine Tufanin, Leonardo Ribeiro Soares
PURPOSE: To investigate if the association of fat grafts and platelet-rich plasma (PRP) improves graft viability in female rats. METHODS: This is an experimental, randomized and blinded study, which involved 47 rats. Fat was harvested from the inguinal region and grafted to the cranial region. The experimental group consisted of PRP-enriched fat grafts (n=22) whilst the control group consisted of fat graft only (n=25). After a 100-day period, the animals were euthanised and the fat grafts were analyzed using scores from 0 (absent) to 4 (abundant), in optical microscopy by two independent and blinded pathologists...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828599/effect-of-estrogen-administration-on-middle-cerebral-arterial-viscoelastic-properties-in-aged-female-rats
#7
Zhigang Qin, Guijie Li, Naijie Liu, Conghai Zhao, Hang Zhao
PURPOSE: To develop a model for studying cerebrovascular disease prevention in elderly women. METHODS: Sixty 18-month-old Sprague Dawley (SD) rats were randomly divided into an estrogen administration group (EA, n=30) and a non-administration group (NA, n=30); thirty 4-month-old SD rats were allocated to a control group. The EA group received estradiol benzoate starting on the 5th day of a 34-day breeding period, and the serum levels of estradiol (E2), estrogen receptor (ER), and malondialdehyde (MDA) were measured...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828598/lipoprotein-lipase-gene-deficient-mice-with-hypertriglyceridaemia-associated-with-acute-pancreatitis
#8
Maochun Tang, Pengfei Zong, Ting Zhang, Dongyan Wang, Yuhui Wang, Yan Zhao
PURPOSE: To investigate the severity of pancreatitis in lipoprotein lipase (LPL)-deficient hypertriglyceridaemic (HTG) heterozygous mice and to establish an experimental animal model for HTG pancreatitis study. METHODS: LPL-deficient HTG heterozygous mice were rescued by somatic gene transfer and mated with wild-type mice. The plasma amylase, triglyceride, and pathologic changes in the pancreas of the LPL-deficient HTG heterozygous mice were compared with those of wild-type mice to assess the severity of pancreatitis...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828597/nutritional-supplementation-with-arginine-protects-radiation-induced-effects-an-experimental-study
#9
Flavia Cristina Morone Pinto, Pamella Campos-Silva, Diogo Benchimol de Souza, Waldemar Silva Costa, Francisco José Barcellos Sampaio
PURPOSE: To investigate the protective effect of L-arginine on the prostate (nonneoplasic) of rats with radiation-induced injury. METHODS: Twenty-nine Wistar rats, male adult, allocated into three groups: Control group (C) was not exposed to irradiation (n=10); Radiated group (R) had undergone pelvic irradiation (n=10); Supplemented and radiated group (R+S) had undergone pelvic irradiation plus L-arginine supplementation (n=9). The animals were observed for signs of toxicity...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27828596/experimental-model-of-glucocorticoid-induced-insulin-resistance
#10
Beatriz Bertolaccini Martínez, Ana Carolina Couto Pereira, Júlio Henrique Muzetti, Fernando de Paiva Telles, Fiorita Gonzáles Lopes Mundim, Manoel Araújo Teixeira
PURPOSE: To evaluate metabolic effects in experimental model of glucocorticoid-induced insulin resistance. METHODS: Twenty Wistar male rats were randomly divided into two groups, which were treated with intraperitoneally injected dexamethasone 1mg/Kg/day for ten days consecutively (Group D; n=10) and placebo (Group C; n=10). The variables analyzed were: from the first to the 10th day - body weight (before and after treatment); food and water daily consumption; on the 10th day - glycemia, insulinemia, HOMA-beta and HOMA-IR...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737350/early-postoperative-recovery-after-intracranial-surgical-procedures-comparison-of-the-effects-of-sevoflurane-and-desflurane
#11
Erhan Gökçek, Ayhan Kaydu, Mehmet Salim Akdemir, Ferit Akil, Ibrahim Ozkan Akıncı
PURPOSE: To compared the effects of sevoflurane and desflurane on early anesthesia recovery in patients undergoing to craniotomy for intracranial lesions. METHODS: After IRB approval, the study included 50 patients aged 18-70 years who had ASA physical statuses of I-II and were scheduled for intracranial surgery. Patients were randomly divided into two groups: sevoflurane and desflurane. Anaesthesia was routinely induced in all patients followed by desflurane 5%-6% or sevoflurane 1%-2%...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737349/morphological-and-immunohistochemical-analysis-of-apoptosis-in-the-cerebellum-of-rats-subjected-to-focal-cerebral-ischemia-with-or-without-alcoholism-model
#12
Camila Albuquerque Melo de Carvalho, Daniela Pretti da Cunha Tirapelli, Andressa Romualdo Rodrigues, Fermino Sanches Lizarte, Paulo Cézar Novais, Jairo Pinheiro Silva, Carlos Gilberto Carlotti, Benedicto Oscar Colli, Luís Fernando Tirapelli
PURPOSE: To evaluated histopathological changes, morphometric and expression of proteins CASPASE-3, BCL-2 and XIAP related to apoptosis in the cerebellum after induction of temporary focal cerebral ischemia followed by reperfusion, with or without a model of chronic alcoholism. METHODS: Fifty Wistar rats were used and divided into: control group (C), sham group (S), ischemic group (I), alcoholic group (A), and ischemic and alcoholic group (IA). The cerebellum samples collected were stained for histopathological and morphometric analysis and immunohistochemistry study...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737348/noradrenaline-and-dobutamine-effects-on-the-volume-expansion-with-normal-saline-in-rabbits-subjected-to-hemorrhage
#13
Gualter Lisboa Ramalho, Matheus Fachini Vane, Luciana Cavalcanti Lima, Lucas Fachini Vane, Rosa Beatriz Amorim, Maria Aparecida Domingues, José Mariano Soares de Moraes, Lídia Raquel de Carvalho, Pedro Paulo Tanaka, Luiz Antonio Vane
PURPOSE: To evaluate the effects of dobutamine (DB), noradrenaline (NA), and their combination (NADB), on volume retention in rabbits submitted to hemorrhage. METHODS: Thirty six rabbits were randomly divided into 6 groups: SHAM, Control, Saline, DB, NA, DB+NA. All the animals, except for SHAM, were subjected to hemorrhage of 25% of the calculated blood volume. Control animals were replaced with their own blood. The other groups received NSS 3 times the volume withdrawn...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737347/l-carnitine-has-a-protective-effect-on-the-colonic-mucosa-during-abdominopelvic-radiotherapy-in-rats
#14
Sukru Tas, Omer Faruk Ozkan, Oztekin Cikman, Asli Kiraz, Yilmaz Akgun, Muammer Karaayvaz
PURPOSE: To evaluate histopathologically the radioprotective effect of L-carnitine on the colonic mucosa in rats undergoing abdominopelvic irradiation. METHODS: Thirty-two rats were randomly assigned to four experimental groups: intraperitoneal administration of normal saline (group 1) or L-carnitine (300 mL/kg; group 2), followed in groups 3 and 4, respectively, by one dose of abdominopelvic radiation (20 Gy) 30 min later. Rats were sacrificed 5 days after radiation, and their descending colons were resected for histopathological evaluation of the presence and severity of damage...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737346/the-effect-of-the-aqueous-extract-peumus-boldus-on-the-proliferation-of-hepatocytes-and-liver-function-in-rats-submitted-to-expanded-hepatectomy
#15
Maria Bernadete Galrão de Almeida Figueiredo, Vanessa Rocha de Santana, Maria Júlia Nardelli, Matheus de Souza Nogueira, Danilo Xavier Azevedo, Danillo Primo Andrade Santana, Ana Galrão de Almeida Figueiredo, Ívison Xavier Duarte, Ricardo Luiz Cavalcanti de Albuquerque, Sônia Oliveira Lima
PURPOSE: To assess the effect of aqueous extract of Peumus Boldus (AEPB) on the liver proliferative response after parcial hepatectomy of 70% (PH) in rodents. METHODS: Twenty Wistar rats were divided in two groups: AEPB100 (whose rats received 100mg/Kg of AEPB, once a day, orally, in 4 days prior to the first surgical procedure) and Vehicle (whose rats were treated similarly with distilled water). Both groups underwent PH. After 24 hours the remaining livers were removed for studying the proliferation of hepatocytes by Ki-67 and 2mL of blood were collected for serological assessment: cholesterol, glucose, triglycerides, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and total, direct and indirect bilirubin...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737345/comparison-between-two-different-experimental-models-of-osteoarthritis-in-rabbits-intra-articular-collagenase-injection-and-anterior-cruciate-ligament-transection
#16
Larissa Correa Hermeto, Rafael De Rossi, Paulo Henrique de Affonseca Jardim, Aureo Evangelista Santana, Jaqueline de Carvalho Rinaldi, Luis Antonio Justulin
PURPOSE: To compare two different experimental models of osteoarthritis in rabbits: intra-articular collagenase injection and anterior cruciate ligament transection. METHODS: Ten adult rabbits were randomly divided in two groups: COLL (collagenase group) and ACLT (anterior cruciate ligament transection). The COLL group was treated with 0.5 ml collagenase solution (2mg collagenase/0.5 ml sterile PBS), and the ACTL group was subjected to anterior cruciate ligament...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737344/antioxidant-effects-of-a%C3%A3-a%C3%A3-seed-euterpe-oleracea-in-anorexia-cachexia-syndrome-induced-by-walker-256-tumor
#17
Vitor Hugo Nunes do Nascimento, Carla Dos Santos Lima, Jorge Tadeu Campos Paixão, Jofre Jacob da Silva Freitas, Katia Simone Kietzer
PURPOSE: To assess antioxidant effects of açaí seed extract on anorexia-cachexia induced by Walker-256 tumor. METHODS: A population of 20 lab rats were distributed into four groups (n=5): Control Group (CG), which only received tumor inoculation. Experimental Group-100 (EG-100), with animals submitted to tumor inoculation and treated with seed extract in a 100 mg / ml concentration through gavage. Experimental Group-200 (EG-200), with animals submitted to tumor inoculation and treated with seed extract in a 200 mg / ml concentration...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737343/oral-or-topical-administration-of-l-arginine-changes-the-expression-of-tgf-and-inos-and-results-in-early-wounds-healing
#18
Márcio Sousa Jerônimo, Adria do Prado Barros, Vinícius Elord Zen MoritaI, Erika Oliveira Alves, Nathalia Lobão Barroso de Souza, Rosane Mansan de Almeida, Yanna Karla Medeiros Nóbrega, Florêncio Figueiredo Cavalcanti, Rivadávio Amorin, Maria de Fátima Borin, Anamélia Lorenzetti Bocca
PURPOSE: To evaluate the contribution of L-arginine oral or topical rout of administration in the surgical wound healing process. METHODS: L-arginine was orally or topically administrated to mice after a laparotomy model procedure. The wounds were analyzed to evaluate the granulation tissue by HE analysis, collagen deposition, iNOS and cytokines production by immunochemisyry on wound progress. Mice used in this model were healthy, immunosupressed or diabetic and all of them were treated with different concentration of L-arginine and rout of administration...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737342/adipose-tissue-stromal-vascular-fraction-in-the-treatment-of-full-thickness-burns-in-rats
#19
Alexandre Lamaro Cardoso, Maria Márcia Bachion, Júlia de Miranda Morais, Marcelo Silva Fantinati, Vera Lúcia Lima de Almeida, Ruy Souza Lino
PURPOSE: To analyze the healing effects of stromal vascular fraction (SVF) application compared to wound dressing with 2% silver sulfadiazine in full thickness burn wounds in rats. METHODS: Animals were divided into two groups: 2% silver sulfadiazine group and SVF group. Both groups received occlusive bandages while the first one was treated with 2% silver sulfadiazine and the latter was treated with injections of SVF prepared from adipose tissue extracted from an animal donor...
September 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27737341/evaluation-of-wound-healing-treated-with-latex-derived-from-rubber-trees-and-aloe-vera-extract-in-rats
#20
Marcelo Luiz Brandão, Paulo Roberto Melo Reis, Lilhian Alves de Araújo, Ana Carolina Vicente Araújo, Maisa Helena de Abreu Silva Santos, Marina Pacheco Miguel
PURPOSE: To compare the use of latex derivative and Aloe vera extract to wound healing. METHODS: Twenty one rats were randomly divided into three groups and each one had a wound made by incision. The treatment consisted in: derivative of latex (GL), Aloe vera extract (GA) and saline solution (GC). The wound area was measured on the 7th, 14th and 21st days and macroscopic and microscopic evaluation were done. RESULTS: The comparison between the measurements of the wounds presented statistical difference in GC and GA from the 7th day of evaluation and GL from the 14th day...
September 2016: Acta Cirúrgica Brasileira
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