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Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging

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https://www.readbyqxmd.com/read/30407679/microvessels-may-confound-the-swallow-tail-sign-in-normal-aged-midbrains-a-postmortem-7-t-sw-mri-study
#1
Thomas Kau, Simon Hametner, Verena Endmayr, Andreas Deistung, Max Prihoda, Evelin Haimburger, Christian Menard, Thomas Haider, Romana Höftberger, Simon Robinson, Jürgen R Reichenbach, Hans Lassmann, Hannes Traxler, Siegfried Trattnig, Günther Grabner
BACKGROUND AND PURPOSE: Susceptibility weighted imaging (SWI) plays a role in the differential diagnosis of Parkinson's disease, but lacks widespread acceptance in clinical routine. In a descriptive pilot study, we assessed hypointense microstructures of the normal substantia nigra pars compacta at ultrahigh-field strength for interpretation of the "swallow tail sign." METHODS: Magnetic resonance imaging at 7 Tesla was performed in five postmortem samples obtained from subjects not affected by Parkinson's disease...
November 8, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30407676/clinical-sonographic-and-electrophysiologic-longitudinal-features-of-chronic-inflammatory-demyelinating-polyneuropathy
#2
Anna Lena Fisse, Kalliopi Pitarokoili, Nadine Trampe, Jeremias Motte, Antonios Kerasnoudis, Ralf Gold, Min-Suk Yoon
BACKGROUND AND PURPOSE: Several studies have aimed to find potential biomarkers to simplify the diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP) and to monitor and predict the disease course. However, reliable markers are still lacking. We aimed to investigate whether high-resolution nerve ultrasound (HRUS) is suitable for monitoring the long-term clinical course of CIDP. METHODS: Twenty patients fulfilling the definite diagnostic criteria of CIDP received clinical examination, evaluation of the INCAT (inflammatory neuropathy cause and treatment) overall disability sum score (ODSS) as well as nerve conduction studies, and HRUS every 6 months over a median follow-up time of 34 months...
November 8, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30398302/what-threshold-defines-penumbral-brain-tissue-in-patients-with-symptomatic-anterior-circulation-intracranial-stenosis-an-exploratory-analysis
#3
Shadi Yaghi, Pooja Khatri, Shyam Prabhakaran, Sharon D Yeatts, Shawna Cutting, Mahesh Jayaraman, Andrew D Chang, Daniel Sacchetti, David S Liebeskind, Karen L Furie
BACKGROUND AND PURPOSE: Impaired distal perfusion predicts neurological deterioration in large artery atherosclerosis. We aim to determine the optimal threshold of Tmax delay on perfusion imaging that is associated with neurological deterioration in patients with symptomatic proximal anterior circulation large artery stenosis. METHODS: Data were abstracted from a prospective ischemic stroke database of consecutively enrolled patients with symptomatic proximal intracranial stenosis (internal carotid artery or M1 segment of the middle cerebral artery) who underwent magnetic resonance perfusion imaging within 24 hours of symptom onset during a 15-month period...
November 6, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30398295/white-matter-microstructure-correlates-with-memory-performance-in-healthy-children-a-diffusion-tensor-imaging-study
#4
Amjad Samara, Kaiyang Feng, R Terry Pivik, Kelly P Jarratt, Thomas M Badger, Xiawei Ou
BACKGROUND AND PURPOSE: The complex function of memory has been linked to both brain gray and white matter (WM). WM abnormalities are associated with memory impairment in pathological conditions. We investigated whether variation in WM microstructure in healthy children also correlates with memory performance. METHODS: Sixty-five 7.5 to 8.5-year-old healthy children had a brain MRI scan using diffusion tensor imaging (DTI). They were also assessed for memory performance using the Children's Memory Scale (CMS)...
November 6, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30378722/pediatric-congenital-cerebrovascular-anomalies
#5
REVIEW
Pradeep Goyal, Rajiv Mangla, Sonali Gupta, Ajay Malhotra, Jeevak Almast, Joshua Sapire, Balasubramanya Kolar
Congenital cerebrovascular anomalies in the pediatric age group are myriad with diverse etiologies. The purpose of this paper is to provide an imaging overview of congenital vascular malformations and vascular tumors, as these conditions are varied and the characteristic vascular abnormality may even suggest the underlying systemic condition in helping to guide further management. For example, the identification of an arterial anomaly such as agenesis/hypoplasia/duplication may warrant further evaluation for an associated syndrome...
October 31, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30376195/diffusely-abnormal-white-matter-t-2-burden-of-disease-and-brain-volume-in-relapsing-remitting-multiple-sclerosis
#6
Alexandra T Vertinsky, David K B Li, Irene M Vavasour, Vladislav Miropolsky, Guojun Zhao, Yinshan Zhao, Andrew Riddehough, G R Wayne Moore, Anthony Traboulsee, Cornelia Laule
BACKGROUND AND PURPOSE: Multiple sclerosis (MS) diffusely abnormal white matter (DAWM) is a mildly hyperintense magnetic resonance imaging abnormality distinct from typical lesions. Our goal was to investigate the prevalence and natural history of DAWM in a large cohort (n = 348) of relapsing-remitting MS (RRMS) patients. METHODS: The presence of DAWM and relationship to changes in T2 burden of disease (BOD), brain volume (brain fractional ratio, BFR), and disability (Expanded Disability Status Scale, EDSS) were investigated at baseline and year 7-8 (long-term follow-up, LTF)...
October 30, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30357980/assessing-the-relationship-between-atherosclerotic-cardiovascular-disease-risk-score-and-carotid-artery-imaging-findings
#7
Ying Li, Guangming Zhu, Victoria Ding, Yonghua Huang, Bin Jiang, Robyn L Ball, Fatima Rodriguez, Dominik Fleischmann, Manisha Desai, David Saloner, Luca Saba, Jason Hom, Max Wintermark
BACKGROUND AND PURPOSE: To characterize the relationship between computed tomography angiography (CTA) imaging characteristics of carotid artery and the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) score. METHODS: We retrospectively identified all patients who underwent a cervical CTA at our institution from January 2013 to July 2016, extracted clinical information, and calculated the 10-year ASCVD score using the Pooled Cohort Equations from the 2013 ACC/AHA guidelines...
October 25, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30325083/the-role-of-diffusion-tensor-imaging-in-detecting-hippocampal-injury-following-neonatal-hypoxic-ischemic-encephalopathy
#8
Jacqueline Salas, Nihaal Reddy, Emanuele Orru, Kathryn A Carson, Raul Chavez-Valdez, Vera Joanna Burton, Carl E Stafstrom, Frances J Northington, Thierry A G M Huisman
BACKGROUND AND PURPOSE: Neonatal hypoxic-ischemic injury of the brain and resultant encephalopathy (HIE) leads to major developmental impairments by school age. Conventional/anatomical MRI often fails to detect hippocampal injury in mild cases. We hypothesize that diffusion tensor imaging (DTI) has greater sensitivity for identifying subtle hippocampal injury. METHODS: We retrospectively analyzed DTI data collected from a cohort of neonates with HIE and controls...
October 16, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30311320/neuroimaging-in-psychiatric-disorders-a-bibliometric-analysis-of-the-100-most-highly-cited-articles
#9
REVIEW
Bo Gong, Sadiq Naveed, Dawood M Hafeez, Khalid I Afzal, Salman Majeed, Jonathan Abele, Savvas Nicolaou, Faisal Khosa
BACKGROUND AND PURPOSE: Extensive research has been conducted to find neuroimaging biomarkers for psychiatric disorders. This study aimed at identifying trends of the 100 most highly cited articles on neuroimaging in primary psychiatric disorders. METHODS: The most highly cited original research articles were identified and analyzed, following searches of MEDLINE and Web of Science All Databases. RESULTS: The top 100 articles ranked by yearly citation (from 137...
October 11, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30302866/functional-brain-network-changes-following-use-of-an-allostatic-closed-loop-acoustic-stimulation-neurotechnology-for-military-related-traumatic-stress
#10
Sung W Lee, Paul J Laurienti, Jonathan H Burdette, Catherine L Tegeler, Ashley R Morgan, Sean L Simpson, Lee Gerdes, Charles H Tegeler
BACKGROUND AND PURPOSE: Post-traumatic stress disorder is associated with connectivity changes in the default mode, central executive, and salience networks, and other brain regions. This study evaluated changes in network connectivity associated with usage of High-resolution, relational, resonance-based electroencephalic mirroring (HIRREM® ; Brain State Technologies, Scottsdale, AZ), a closed-loop, allostatic, acoustic stimulation neurotechnology, for military-related traumatic stress...
October 10, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30302863/arterial-spin-labeling-mri-to-measure-cerebral-blood-flow-in-untreated-ischemic-stroke
#11
Girolamo Crisi, Silvano Filice, Umberto Scoditti
BACKGROUND AND PURPOSE: This study aims to investigate the significance of regional hyperperfusion (RH) detected by arterial spin labeling (ASL) in a group of untreated stroke patients, within 24-36 hours after symptom onset. The relationship between RH volume and infarcted volume (DIV) as defined on diffusion weighted images (DWIs) was evaluated. METHODS: Of the 346 consecutive acute stroke patients who attended our center, we retrospectively reviewed MRI studies of 47 patients who were ineligible for standard treatment with intravenous tissue plasminogen activator...
October 9, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30295987/mri-guided-high-intensity-focused-ultrasound-as-an-emerging-therapy-for-stroke-a-review
#12
REVIEW
Atif Zafar, Syed A Quadri, Mudassir Farooqui, Santiago Ortega-Gutiérrez, Omid R Hariri, Maryam Zulfiqar, Asad Ikram, Muhammad Adnan Khan, Sajid S Suriya, Joel R Nunez-Gonzalez, Stefan Posse, Martin M Mortazavi, Howard Yonas
Stroke, either ischemic or hemorrhagic, accounts for significantly high morbidity and mortality rates around the globe effecting millions of lives annually. For the past few decades, ultrasound has been extensively investigated to promote clot lysis for the treatment of stroke, myocardial infarction, and acute peripheral arterial occlusions, with or without the use of tPA or contrast agents. In the age of modern minimal invasive techniques, magnetic resonance imaging-guided high-intensity focused ultrasound is a new emerging modality that seems to promise therapeutic utilities for both ischemic and hemorrhagic stroke...
October 8, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30295979/gliosarcoma-neuroimaging-and-immunohistochemical-findings
#13
Miriam E Peckham, Anne G Osborn, Cheryl A Palmer, Amy Tsai, Karen L Salzman
BACKGROUND AND PURPOSE: Gliosarcoma (GSC) is an intra-axial lesion which often abuts a dural margin and is composed of glial and mesenchymal elements. This lesion is considered a variant of isocitrate dehydrogenase (IDH)-wild type glioblastoma (GBM). The purpose of this study is to evaluate the imaging and molecular features of GSC in a large patient cohort. METHODS: Pathology-proved GSC cases were collected from our quaternary care center spanning the last 16 years and IDH status was documented...
October 8, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30285300/brief-computer-based-information-processing-measures-are-linked-to-white-matter-integrity-in-pediatric-onset-multiple-sclerosis
#14
Elizabeth Bartlett, Michael Shaw, Colleen Schwarz, Charles Feinberg, Christine DeLorenzo, Lauren B Krupp, Leigh E Charvet
BACKGROUND AND PURPOSE: Pediatric-onset multiple sclerosis (POMS) is a demyelinating disorder with unique clinical challenges. A brief computer-administered cognitive screening battery measuring processing speed (Cogstate) and the Brief International Cognitive Assessment in MS (BICAMS) detect cognitive impairment in POMS. The neuroanatomic correlates of these deficits are incompletely understood. The purpose of this study is to define the neuroanatomic underpinnings of deficits identified with cognitive screening batteries in POMS...
October 4, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30232810/teriflunomide-s-effect-on-glia-in-experimental-demyelinating-disease-a-neuroimaging-and-histologic-study
#15
Suyog Pol, Michele Sveinsson, Michelle Sudyn, Natan Babek, Danielle Siebert, Nicola Bertolino, Claire M Modica, Marilena Preda, Ferdinand Schweser, Robert Zivadinov
BACKGROUND AND PURPOSE: Teriflunomide reduces disability progression and brain atrophy in multiple sclerosis patients. The exact mechanism of action by which teriflunomide exerts these effects is currently unknown. We assessed the effect of teriflunomide on brain glial cells in the Theiler's murine encephalomyelitis virus (TMEV) by using a histological approach in combination with neuroimaging. METHODS: Forty-eight SJL female mice received an intracerebral injection of TMEV at 6-8 weeks of age and were then treated with teriflunomide (n = 24) or placebo (n = 24) for 9 months...
September 19, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30230638/multicenter-measurements-of-t-1-relaxation-and-diffusion-tensor-imaging-intra-and-intersite-reproducibility
#16
Irene M Vavasour, Sandra M Meyers, Burkhard Mädler, Trudy Harris, Eric Fu, David K B Li, Anthony Traboulsee, Alex L MacKay, Cornelia Laule
BACKGROUND AND PURPOSE: Quantitative T1 and diffusion tensor imaging (DTI) may provide information about pathological changes underlying disability and progression in diseases like multiple sclerosis (MS). Imaging the corpus callosum (CC), a primary site of damage in MS with a critical role in interhemispheric connectivity, may be useful for assessing overall brain health, prognosis, and therapy efficacy. We assessed the feasibility of multisite clinical trials using advanced MRI by examining the intra and intersite reproducibility of T1 and DTI measurements in the CC and segmented white matter (WM)...
September 19, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30230118/18f-fpeb-pet-ct-shows-mglur5-upregulation-in-parkinson-s-disease
#17
Yeona Kang, Claire Henchcliffe, Ajay Verma, Shankar Vallabhajosula, Bin He, Paresh J Kothari, Kane O Pryor, P David Mozley
BACKGROUND AND PURPOSE: Dopamine and glutamate reciprocally regulate each other in some of the neurocircuits affected by Parkinson's disease (PD). The objective of this pilot study was to explore relationships between these neurotransmitter systems with positron emission tomography. METHODS: The sample consisted of nine patients with PD and eight healthy volunteers (HVs). Dynamic images of the brain were acquired after the IV administration of ∼370 MBq (10 mCi) of [11 C]PE2i, a dopamine transporter (DaT) imaging agent, and ∼185 MBq (∼5 mCi) of [18 F]FPEB, a selective metabotropic glutamate receptor 5 (mGluR5) antagonist...
September 19, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30230093/baseline-aspects-and-e-aspects-correlation-with-infarct-volume-and-functional-outcome-in-patients-undergoing-mechanical-thrombectomy
#18
Marta Olive-Gadea, Nuno Martins, Sandra Boned, Jaime Carvajal, Maria Jose Moreno, Marian Muchada, Carlos A Molina, Alejandro Tomasello, Marc Ribo, Marta Rubiera
BACKGROUND AND PURPOSE: The role of Alberta Stroke Program Early CT score (ASPECTS) in predicting which patients are likely to benefit from endovascular therapy (EVT) is not well defined. An automated software (e-ASPECTS) has been created to solve its poor interrater reliability. We aim to evaluate correlation between radiologist (Rx) and e-ASPECTS scoring with cerebral blood volume (CBV) infarct core and with final infarct volume; as well as with long-term functional outcome. METHODS: We included patients with acute ischemic stroke and large vessel occlusion who underwent EVT...
September 19, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30230091/ct-reconstruction-levels-affect-automated-and-reader-based-aspects-ratings-in-acute-ischemic-stroke
#19
Fatih Seker, Johannes Pfaff, Simon Nagel, Dominik Vollherbst, Stephen Gerry, Markus A Möhlenbruch, Martin Bendszus, Christian Herweh
BACKGROUND AND PURPOSE: We investigated whether automated and reader-based ASPECTS in acute stroke patients are affected by different CT image reconstruction algorithms. METHODS: ASPECTS were assessed by commercial software and four independent blinded readers (two residents and two consultants) from different CT reconstructions (filtered back projection and two different iterative reconstruction [IR] levels) in 43 acute stroke patients with proximal middle cerebral artery occlusion...
September 19, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30209849/mri-profile-and-collateral-status-in-patients-with-a-transient-ischemic-attack-and-an-intracranial-artery-occlusion
#20
Elodie Ong, Omer Eker, Leila Chamard, Tae Hee Cho, Laurent Derex, Marielle Buisson, Laura Mechtouff, Yves Berthezene, Norbert Nighoghossian
BACKGROUND AND PURPOSE: Transient ischemic attack may rarely reveal an intracranial artery occlusion. We analyzed acute magnetic resonance imaging (MRI) patterns and early outcome after reperfusion therapy in these cases. METHOD: Clinical and imaging data were taken retrospectively from our comprehensive stroke center registry. Two MRI patterns were determined. Pattern A: full mismatch with negative diffusion-weighted imaging (DWI) and perfusion defect. Pattern B: large mismatch with positive DWI and perfusion defect...
September 12, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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