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Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging

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https://www.readbyqxmd.com/read/29134725/reproducibility-of-brain-mri-segmentation-algorithms-empirical-comparison-of-local-map-pstaple-freesurfer-and-fsl-first
#1
Clemente Velasco-Annis, Alireza Akhondi-Asl, Aymeric Stamm, Simon K Warfield
BACKGROUND AND PURPOSE: Segmentation of human brain structures is crucial for the volumetric quantification of brain disease. Advances in algorithmic approaches have led to automated techniques that save time compared to interactive methods. Recently, the utility and accuracy of template library fusion algorithms, such as Local MAP PSTAPLE (PSTAPLE), have been demonstrated but there is little guidance regarding its reproducibility compared to single template-based algorithms such as FreeSurfer and FSL-FIRST...
November 14, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29134723/the-ct-defined-hyperdense-arterial-sign-as-a-marker-for-acute-intracerebral-large-vessel-occlusion
#2
Jaims Lim, Jordan A Magarik, Michael T Froehler
BACKGROUND AND PURPOSE: To determine the sensitivity and specificity of the hyperdense artery sign (HAS) on thin-slice non-contrast computed tomography (NCCT), combined with brief clinical history, as an indicator for large vessel occlusion (LVO) in the setting of acute ischemic stroke. METHODS: Ninety-nine LVO and 102 non-LVO acute ischemic stroke patients were retrospectively identified from a prospective database at a single institution. After reviewing each patient's neurologic presentation based on his or her initial National Institute of Health Stroke Scale (NIHSS) and neurologic evaluation, all thin (1 mm) and thick (5 mm) NCCT scans were reviewed for the HAS...
November 14, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29124813/a-simplified-quantitative-method-to-measure-brain-shifts-in-patients-with-middle-cerebral-artery-stroke
#3
Nina Paletta, Laith Maali, Abdurrehman Zahran, Sankara Sethuraman, Ramon Figueroa, Fenwick T Nichols, Askiel Bruno
BACKGROUND AND PURPOSE: A standardized and validated method to measure brain shifts in malignant middle cerebral artery (MCA) stroke with decompressive hemicraniectomy (DHC) could facilitate clinical decision making, prognostication, and comparison of results between studies. METHODS: We tested for reliability simplified methods to measure transcalvarial herniation, midline brain shift, and the contralateral cerebral ventricular atrium in malignant MCA stroke after DHC...
November 10, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29076591/long-term-magnetization-transfer-ratio-evolution-in-multiple-sclerosis-white-matter-lesions
#4
Yufan Zheng, Jar-Chi Lee, Richard Rudick, Elizabeth Fisher
BACKGROUND AND PURPOSE: Magnetization transfer ratio (MTR), a magnetic resonance imaging technique used to assess tissue integrity, correlates with demyelination and axonal loss in multiple sclerosis (MS) lesions. In acute white matter lesions, short-term MTR changes mainly reflect demyelination and remyelination, in addition to edema and axonal and glial changes. Long-term MTR changes in MS lesions have not been studied extensively. METHODS: A new quantitative image analysis method was developed to measure long-term MTR changes in MS lesions...
October 27, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29064155/assessing-inflammation-in-acute-intracerebral-hemorrhage-with-pk11195-pet-and-dynamic-contrast-enhanced-mri
#5
Kamran A Abid, Oluwaseun A Sobowale, Laura M Parkes, Josephine Naish, Geoff J M Parker, Daniel du Plessis, David Brough, Jack Barrington, Stuart M Allan, Rainer Hinz, Adrian R Parry-Jones
BACKGROUND AND PURPOSE: Studies in animal models suggest that inflammation is a major contributor to secondary injury after intracerebral hemorrhage (ICH). Direct, noninvasive monitoring of inflammation in the human brain after ICH will facilitate early-phase development of anti-inflammatory treatments. We sought to investigate the feasibility of multimodality brain imaging in subacute ICH. METHODS: Acute ICH patients were recruited to undergo multiparametric MRI (including dynamic contrast-enhanced measurement of blood-brain barrier transfer constant (K(trans) ) and PET with [(11) C]-(R)-PK11195)...
October 24, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29064137/diffusion-tensor-imaging-shows-corpus-callosum-differences-between-high-grade-gliomas-and-metastases
#6
Nicholas S Cho, Mehrnaz Jenabi, Julio Arevalo-Perez, Nicole Brennan, Robert J Young, Sasan Karimi, Andrei I Holodny, Kyung K Peck
BACKGROUND AND PURPOSE: The corpus callosum (CC) has an important role in regulating interhemispheric transfer and is thought to be instrumental in contralateral brain reorganization in patients with brain tumors, as suggested by a previous study reporting callosal differences between language dominance groups through diffusion tensor imaging (DTI) characteristics. The purpose of this study was to explore the structural differences in the CC between high-grade gliomas (HGGs) and metastatic tumors (METs) using the DTI characteristics of fractional anisotropy (FA), mean diffusivity (MD), and axial diffusivity (AD)...
October 24, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29064129/validating-nonlinear-registration-to-improve-subtraction-images-for-lesion-detection-and-quantification-in-multiple-sclerosis
#7
Vikas Kotari, Racha Salha, Dana Wang, Emily Wood, Marco Salvetti, Giovanni Ristori, Larry Tang, Francesca Bagnato, Vasiliki N Ikonomidou
BACKGROUND AND PURPOSE: To propose and validate nonlinear registration techniques for generating subtraction images because of their ability to reduce artifacts and improve lesion detection and lesion volume quantification. METHODS: Postcontrast T1 -weighted spin echo and T2 -weighted dual echo images were acquired for 20 patients with relapsing-remitting multiple sclerosis (RRMS) on a monthly basis for a year (14 women, average age 33.6 ± 6.9). The T2 -weighted images from the first scan were used as a baseline for each patient...
October 24, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28984397/intra-arterial-modulation-of-the-trigeminal-nerve-ganglion-in-patients-with-refractory-trigeminal-neuralgia
#8
Adnan I Qureshi, Muhammad A Saleem, Vikram Jadhav, Shawn S Wallery, Faisal Raja
BACKGROUND AND PURPOSE: Nerves and nerve ganglions are supplied by segmental arteries and the vasa nervorum, but the intra-arterial route has not been used for diagnostic or therapeutic purposes. We present the results of intra-arterial delivery of medication for modulating trigeminal nerve ganglion function in patients with refractory trigeminal neuralgia. METHODS: We administered intra-arterial lidocaine in doses up to 50 mg in the middle meningeal artery territory adjacent to the arterial branch that supplies the trigeminal nerve ganglion...
October 6, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28945289/anomalies-and-normal-variants-of-the-cerebral-arterial-supply-a-comprehensive-pictorial-review-with-a-proposed-workflow-for-classification-and-significance
#9
REVIEW
Arsany Hakim, Jan Gralla, Christoph Rozeik, Pasquale Mordasini, Lars Leidolt, Eike Piechowiak, Christoph Ozdoba, Marwan El-Koussy
Cerebral arteries may exhibit a wide range of variation from normal anatomy, which can be incidentally discovered during imaging. Knowledge of such variants is crucial to differentiate them from pathologies, to understand the etiology of certain pathologies directly related to a vascular variant, and to depict the changes in collateral circulation in patients with certain variants. Detection of particular variants may lead to the discovery of other nonvascular or vascular anomalies, especially aneurysms, and may also affect planning of endovascular or neurosurgical interventions...
September 25, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28944575/seven-tesla-magnetization-transfer-imaging-to-detect-multiple-sclerosis-white-matter-lesions
#10
I-Jun Chou, Su-Yin Lim, Radu Tanasescu, Ali Al-Radaideh, Olivier E Mougin, Christopher R Tench, William P Whitehouse, Penny A Gowland, Cris S Constantinescu
BACKGROUND AND PURPOSE: Fluid-attenuated inversion recovery (FLAIR) imaging at 3 Tesla (T) field strength is the most sensitive modality for detecting white matter lesions in multiple sclerosis. While 7T FLAIR is effective in detecting cortical lesions, it has not been fully optimized for visualization of white matter lesions and thus has not been used for delineating lesions in quantitative magnetic resonance imaging (MRI) studies of the normal appearing white matter in multiple sclerosis...
September 25, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28940825/cluster-confidence-index-a-streamline-wise-pathway-reproducibility-metric-for-diffusion-weighted-mri-tractography
#11
Kesshi M Jordan, Bagrat Amirbekian, Anisha Keshavan, Roland G Henry
BACKGROUND: Diffusion-weighted magnetic resonance imaging tractography can be used to create models of white matter fascicles. Anatomical and pathological variability between subjects can drastically alter the tractography output, so standardizing results across a cohort is nontrivial. Furthermore, tractography methods have inherently low reproducibility due to stochasticity (for probabilistic methods) and subjective decisions, since the final fascicle model often requires a manual intervention step performed by an expert human operator to control both outliers and systematic false-positive pathways, as defined by prior knowledge of anatomy...
September 21, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28736910/longitudinal-mr-spectroscopy-shows-altered-metabolism-in-traumatic-brain-injury
#12
Andrew A Maudsley, Varan Govind, Gaurav Saigal, Stuart G Gold, Leo Harris, Sulaiman Sheriff
BACKGROUND AND PURPOSE: Brain trauma is known to result in heterogeneous patterns of tissue damage and altered neuronal and glial metabolism that evolve over time following injury; however, little is known on the longitudinal evolution of these changes. In this study, magnetic resonance spectroscopic imaging (MRSI) was used to map the distributions of altered metabolism in a single subject at five time points over a period of 28 months following injury. METHODS: Magnetic resonance imaging and volumetric MRSI data were acquired in a subject that had experienced a moderate traumatic brain injury (Glasgow Coma Scale 13) at five time points, from 7 weeks to 28 months after injury...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28661060/decreased-glutamate-levels-in-patients-with-amnestic-mild-cognitive-impairment-an-slaser-proton-mr-spectroscopy-and-pib-pet-study
#13
Burcu Zeydan, Dinesh K Deelchand, Nirubol Tosakulwong, Timothy G Lesnick, Orhun H Kantarci, Mary M Machulda, David S Knopman, Val J Lowe, Clifford R Jack, Ronald C Petersen, Gülin Öz, Kejal Kantarci
BACKGROUND AND PURPOSE: Glutamate levels may be informative about the declining neuronal health in the central nervous system. We used an advanced proton MR spectroscopy ((1) H-MRS) protocol composed of semi-localization by adiabatic selective refocusing (sLASER) localization and FAST(EST)MAP shimming for detection of alterations in brain glutamate concentrations in patients with amnestic mild cognitive impairment. METHODS: Participants with amnestic mild cognitive impairment (n = 14; median age = 80) and age- and sex-matched clinically normal controls (n = 32; median age = 79) from the population-based Mayo Clinic Study of Aging were recruited prospectively to the 3T single-voxel (1) H-MRS study that examined metabolite changes in the posterior cingulate gyri...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28654166/lesions-in-the-splenium-of-the-corpus-callosum-on-mri-in-children-a-review
#14
REVIEW
Marinos Kontzialis, Bruno P Soares, Thierry A G M Huisman
A wide variety of conditions may involve the splenium of the corpus callosum on magnetic resonance imaging in children. A single cause may present with different patterns of splenial involvement, and multiple diseases may have similar imaging findings. Keeping this limitation in mind, the goal of this text is to assist in the diagnostic process of pediatric neurological diseases that are characterized by prominent involvement of the splenium of the corpus callosum on imaging. The various pathologies will be reviewed and categorized based on etiology, reversibility, and pattern of additional or associated findings...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28574627/ct-versus-mr-techniques-in-the-detection-of-cervical-artery-dissection
#15
Uta Hanning, Peter B Sporns, Meilin Schmiedel, Erich B Ringelstein, Walter Heindel, Heinz Wiendl, Thomas Niederstadt, Ralf Dittrich
BACKGROUND: Spontaneous cervical artery dissection (sCAD) is an important etiology of juvenile stroke. The gold standard for the diagnosis of sCAD is convential angiography. However, magnetic resonance imaging (MRI)/MR angiography (MRA) and computed tomography (CT)/CT angiography (CTA) are frequently used alternatives. New developments such as multislice CT/CTA have enabled routine acquisition of thinner sections with rapid imaging times. The goal of this study was to compare the capability of recent developed 128-slice CT/CTA to MRI/MRA to detect radiologic features of sCAD...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28524459/prognostic-role-of-conventional-and-dynamic-contrast-enhanced-mri-in-optic-pathway-gliomas
#16
Nutchawan Jittapiromsak, Ping Hou, Ho-Ling Liu, Jia Sun, John M Slopis, T Linda Chi
BACKGROUND AND PURPOSE: The natural history of optic pathway glioma (OPG) is highly variable and unpredictable. We present a pilot study of the prognostic role of conventional and dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) in the evaluation of OPG. METHODS: We retrospectively reviewed 17 patients with 20 pretreatment OPG lesions who underwent conventional and DCE MRI between January 2010 and December 2016. Conventional MRI was evaluated for enhancement pattern, cystic component, optic nerve tortuosity, optic nerve dural ectasia, and optic nerve perineural thickening...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28524416/diagnostic-ultrasound-of-the-vagus-nerve-in-patients-with-diabetes
#17
Eman A Tawfik, Francis O Walker, Michael S Cartwright, Rana A El-Hilaly
BACKGROUND AND PURPOSE: Autonomic neuropathy is a serious and common complication of diabetes mellitus. The vagus nerve is the longest autonomic nerve, and may be affected in diabetes as a part of generalized neuropathy. Our objective was to assess for possible sonographic changes of the vagus nerve in diabetic patients. METHODS: The vagus nerve was bilaterally scanned in 20 healthy volunteers and 54 patients with diabetes in the axial plane at the lateral neck...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28514045/contrast-extravasation-versus-hemorrhage-after-thrombectomy-in-patients-with-acute-stroke
#18
Vivek Yedavalli, Steffen Sammet
BACKGROUND AND PURPOSE: Intra-arterial recanalization postprocedural imaging in stroke patients can result in diagnostic complications due to hyperdensities on noncontrast computed tomography (CT), which may represent either contrast extravasation or intracranial hemorrhage. If these lesions are hemorrhage, then they are risk factors becoming symptomatic, which, if not distinguished, can alter clinical management. We investigate the effects of iodinated contrast on postprocedural magnetic resonance imaging (MRI) and prevalence of equivocal imaging interpretations of postprocedural extravasated contrast versus hemorrhage while identifying protocol pitfalls...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28488804/three-dimensional-shape-and-surface-features-distinguish-multiple-sclerosis-lesions-from-nonspecific-white-matter-disease
#19
Braeden D Newton, Katy Wright, Mandy D Winkler, Francesca Bovis, Masaya Takahashi, Ivan E Dimitrov, Maria Pia Sormani, Marco C Pinho, Darin T Okuda
BACKGROUND AND PURPOSE: There remains a need to further refine the ability of clinicians to differentiate multiple sclerosis (MS) from other disease etiologies. Here, we illustrate the value of 3-dimensional (3D) geometric shape and surface lesion characteristics between disease states. METHODS: Standardized 3-Tesla 3D brain magnetic resonance imaging studies were performed on enrolled MS and nonspecific white matter (NSWM) patients. Focal supratentorial lesions were identified, reconstructed using maximum intensity projection, manually segmented, and 3D printed...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28464417/a-novel-semiautomated-pipeline-to-measure-brain-atrophy-and-lesion-burden-in-multiple-sclerosis-a-long-term-comparative-study
#20
Tomas Uher, Jan Krasensky, Manuela Vaneckova, Lukas Sobisek, Zdenek Seidl, Eva Havrdova, Niels Bergsland, Michael G Dwyer, Dana Horakova, Robert Zivadinov
BACKGROUND AND PURPOSE: Lesion burden and brain volume changes are frequent end points in research but nowadays are becoming important in the clinical practice of multiple sclerosis (MS). The objective of this study was to investigate the correlation between magnetic resonance imaging (MRI) measures obtained by in-house developed ScanView software and commonly used volumetric techniques for assessment of T2 lesion and whole brain volumes and their changes. METHODS: Together 3,340 MRI scans from 209 patients after first demyelinating event suggestive of MS, 181 relapsing-remitting MS patients and 43 controls were analyzed...
November 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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