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Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging

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https://www.readbyqxmd.com/read/30010229/the-frequency-of-substantial-salvageable-penumbra-in-thrombectomy-ineligible-patients-with-acute-stroke
#1
Mersedeh Bahr Hosseini, Graham Woolf, Latisha K Sharma, Jason D Hinman, Neal M Rao, Bryan Yoo, Reza Jahan, Sidney Starkman, May Nour, Radoslav Raychev, David S Liebeskind, Jeffrey L Saver
BACKGROUND AND PURPOSE: Endovascular therapy (ET) has become the standard of care for selected patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO). However, many LVO or medium vessel occlusion (MVO) patients are ineligible for ET, including some who harbor salvageable tissues. To develop complementary therapies for these patients, it is important to delineate their prevalence, clinical features, and outcomes. METHODS: In a prospectively maintained database, we reviewed consecutive AIS patients between December 2015 and September 2016...
July 16, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29999204/use-of-the-nesma-filter-to-improve-myelin-water-fraction-mapping-with-brain-mri
#2
Mustapha Bouhrara, David A Reiter, Michael C Maring, Jean-Marie Bonny, Richard G Spencer
BACKGROUND AND PURPOSE: Myelin water fraction (MWF) mapping permits direct visualization of myelination patterns in the developing brain and in pathology. MWF is conventionally measured through multiexponential T2 analysis which is very sensitive to noise, leading to inaccuracies in derived MWF estimates. Although noise reduction filters may be applied during postprocessing, conventional filtering can introduce bias and obscure small structures and edges. Advanced nonblurring filters, while effective, exhibit a high level of complexity and the requirement for supervised implementation for optimal performance...
July 12, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29992676/real-time-cerebral-hemodynamic-response-to-tactile-somatosensory-stimulation
#3
Benjamin Hage, Emily Way, Steven M Barlow, Gregory R Bashford
BACKGROUND AND PURPOSE: Recent studies in rodents suggest that somatosensory stimulation could provide neuroprotection during ischemic stroke by inducing plasticity in the cortex-vasculature relationship. While functional magnetic resonance imaging (fMRI) has shown that somatosensory stimulation increases cerebral blood flow (CBF) over several seconds, subsecond changes in CBF in the basal cerebral arteries have rarely been studied due to temporal resolution limitations. This study characterized hemodynamic changes in the middle cerebral arteries (MCAs) during somatosensory stimulation with high temporal resolution (100 samples/s) using functional transcranial Doppler ultrasound (fTCD)...
July 10, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29989259/mdp-spect-versus-hybrid-mdp-spect-ct-in-the-evaluation-of-suspected-pars-interarticularis-fracture-in-young-athletes
#4
Santhosh Gaddikeri, Manuela Matesan, Jacqueline Alvarez, Daniel S Hippe, Hubert J Vesselle
BACKGROUND AND PURPOSE: To assess benefits of hybrid (single photon emission computerized tomography [SPECT]/computed tomography [CT]) imaging over SPECT imaging only in the management of young athletes with low back pain (LBP) due to suspected pars interarticularis fracture. METHODS: Retrospectively reviewed medical records of 163 consecutive patients who had radionuclide SPECT imaging for evaluation of LBP between January 1, 2010 and December 30, 2015. All enrolled patients were divided into two groups (group 1: patients with radionuclide SPECT imaging only and group 2: patients with radionuclide hybrid imaging)...
July 10, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29975004/structural-complexity-of-the-cerebellum-and-cerebral-cortex-is-reduced-in-spinocerebellar-ataxia-type-2
#5
Chiara Marzi, Stefano Ciulli, Marco Giannelli, Andrea Ginestroni, Carlo Tessa, Mario Mascalchi, Stefano Diciotti
BACKGROUND AND PURPOSE: Fractal dimension (FD) is an index of structural complexity of cortical gray matter (GM) and white matter (WM). Application of FD to pontocerebellar degeneration has revealed cerebellar changes. However, so far, possible concurrent cerebral changes and progression of changes in brain complexity have not been investigated. METHODS: We computed FD of cerebellar and cerebral cortex and WM derived from longitudinal brain MRI of patients with spinocerebellar ataxia type 2 (SCA2), which is an inherited cause of pontocerebellar degeneration...
July 5, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29917285/comparison-of-carotid-doppler-ultrasound-to-other-angiographic-modalities-in-the-measurement-of-carotid-artery-stenosis
#6
Matthew Boyko, Hayrapet Kalashyan, Harald Becher, Helen Romanchuk, Maher Saqqur, Jeremy L Rempel, Carol Derksen, Ashfaq Shuaib, Khurshid Khan
BACKGROUND AND PURPOSE: The purpose of this study was to compare Doppler ultrasound (DUS) to other angiographic modalities: computed tomography angiography (CTA), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA). METHODS: All DUS studies performed at Stroke Prevention Clinic (SPC) from 2011 to 2013 and referred for further angiographic modalities were included. Patients were excluded if the corresponding angiographic modality was not performed within 6 months of DUS...
June 19, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29905019/i-123-datscan-spect-brain-imaging-in-parkinsonian-syndromes-utility-of-the-putamen-to-caudate-ratio
#7
Manuela Matesan, Santhosh Gaddikeri, Katelan Longfellow, Robert Miyaoka, Saeed Elojeimy, Shana Elman, Shu-Ching Hu, Satoshi Minoshima, David Lewis
BACKGROUND AND PURPOSE: Computer-based analysis of Dopamine transporter imaging (DaTscan) can aid in image interpretation. In this study, we examined the distribution of putamen-to-caudate ratios (PCRs) obtained by using a clinically available semiquantification method. METHODS: Medical records of 32 patients (M:16) with a diagnosis of Parkinson's disease (PD) (n = 22) or Parkinson's plus syndromes (PPS) (n = 10) based on clinical follow-up, were retrospectively reviewed...
June 14, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29893064/yakovlev-s-basolateral-limbic-circuit-in-multiple-sclerosis-related-cognitive-impairment
#8
Zafer Keser, Arash Kamali, Kyan Younes, Paul E Schulz, Flavia M Nelson, Khader M Hasan
BACKGROUND AND PURPOSE: In 1948, Paul Yakovlev described an additional limbic circuit located basolateral to James Papez's circuit (1937) and included orbitofrontal cortex, amygdala, and dorsomedial nucleus of thalamus. This circuit is shown to be an important component of subcortical cognitive abilities. We aimed to demonstrate this circuit in a multiple sclerosis (MS) cohort using diffusion tensor imaging (DTI) and evaluate its role in MS-related cognitive impairment (CI). METHODS: We enrolled cognitively intact (n = 10) and impaired (n = 36) MS patients who underwent a comprehensive cognitive assessment; the minimal assessment of cognitive function in MS (MACFIMS) and structural magnetic resonance imaging...
June 12, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29883008/transorbital-sonography-for-early-prognostication-of-hypoxic-ischemic-encephalopathy-after-cardiac-arrest
#9
Michael Ertl, Sarah Weber, Gertrud Hammel, Christoph Schroeder, Christos Krogias
BACKGROUND AND PURPOSE: Early prognostication of the outcome in resuscitated post cardiac arrest (CA) patients remains challenging especially if treated with therapeutic hypothermia. Brain edema caused by hypoxic-ischemic encephalopathy (HIE) can indirectly be estimated by transorbital sonography (TOS) taking in account the optic nerve sheath diameter (ONSD). The prognostic value of this easy, safe, and reproducible technique was investigated in this study. METHODS: A total of 49 patients, initially unconscious (Glasgow Coma Scale ≤6) after successful resuscitation, were enrolled into this prospective observational study...
June 8, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29883005/emotional-processing-in-the-first-2-years-of-life-a-review-of-near-infrared-spectroscopy-studies
#10
Ambika Maria, Shashank Shekhar, Ilkka Nissilä, Kalle Kotilahti, Minna Huotilainen, Linnea Karlsson, Hasse Karlsson, Jetro J Tuulari
Emotional stimuli processing during childhood helps us to detect salient cues in our environment and prepares us for our social life. In early childhood, the emotional valences of auditory and visual input are salient and relevant cues of social aspects of the environment, and it is of special interest to understand how exactly the processing of emotional stimuli develops. Near-infrared spectroscopy (NIRS) is a noninvasive neuroimaging tool that has proven valuable in studying emotional processing in children...
June 8, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29856910/atrophied-brain-lesion-volume-a-new-imaging-biomarker-in-multiple-sclerosis
#11
Michael G Dwyer, Niels Bergsland, Deepa P Ramasamy, Dejan Jakimovski, Bianca Weinstock-Guttman, Robert Zivadinov
BACKGROUND AND PURPOSE: Lesion accrual in multiple sclerosis (MS) is an important and clinically relevant measure, used extensively as an imaging trial endpoint. However, lesions may also shrink or disappear entirely due to atrophy. Although generally ignored or treated as a nuisance, this phenomenon may actually be an important stand-alone imaging biomarker. Therefore, we investigated the rate of brain lesion loss due to atrophy (atrophied lesion volume) in MS subtypes compared to baseline lesion volume and to new and enlarging lesion volumes, and evaluated the independent predictive value of this phenomenon for clinical disability...
June 1, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29797626/embryonal-tumor-with-multilayered-rosettes-c19mc-altered-clinical-pathological-and-neuroimaging-findings
#12
Bing Wang, Bhanu Gogia, Gregory N Fuller, Leena M Ketonen
BACKGROUND AND PURPOSE: Embryonal tumor with multilayered rosettes (ETMR), C19MC-altered, is a recently described, rare central nervous system tumor. To our knowledge, the imaging findings of this tumor have not been systematically evaluated in the neuroradiology literature. We present here the clinical, radiological, and pathological correlation of a case series of this very rare tumor, including the full range of anatomic compartment presentations (supratentorial, infratentorial, and spinal)...
May 24, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29797614/comparative-analysis-of-markers-of-mass-effect-after-ischemic-stroke
#13
Ann-Christin Ostwaldt, Thomas W K Battey, Hannah J Irvine, Bruce C V Campbell, Stephen M Davis, Geoffrey A Donnan, W Taylor Kimberly
BACKGROUND AND PURPOSE: Midline shift determined on magnetic resonance imaging (MRI) or computed tomography (CT) images is a well-validated marker of mass effect after large hemispheric infarction and associated with mortality. In this study, we targeted a population with moderately sized strokes. We compared midline shift to other imaging markers and determined their ability to predict long-term outcome. METHODS: MRI scans were studied from the Echoplanar Imaging Thrombolysis Evaluation Trial (EPITHET) cohort...
May 24, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29797465/concomitant-acute-toxic-leukoencephalopathy-and-posterior-reversible-encephalopathy-syndrome
#14
Can Özütemiz, Sarah Khanipour Roshan, Neil Joseph Kroll, Jeffrey B Rykken, Frederick Ott, Alexander M McKinney
BACKGROUND AND PURPOSE: Posterior reversible encephalopathy syndrome (PRES) and acute toxic leukoencephalopathy (ATL) are both potentially reversible clinicoradiologic entities. Although their magnetic resonance imaging (MRI) findings differ, rarely both may occur simultaneously in acutely encephalopathic patients. Our aim was to determine the incidence and causes of concomitant "ATL-PRES." METHODS: Retrospective search of suspected acutely encephalopathic adults since 1998 throughout our picture archiving and communication system revealed 167 patients with PRES and 106 patients with ATL...
May 24, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29766613/cortical-thickness-estimations-of-freesurfer-and-the-cat12-toolbox-in-patients-with-alzheimer-s-disease-and-healthy-controls
#15
Rene Seiger, Sebastian Ganger, Georg S Kranz, Andreas Hahn, Rupert Lanzenberger
BACKGROUND AND PURPOSE: Automated cortical thickness (CT) measurements are often used to assess gray matter changes in the healthy and diseased human brain. The FreeSurfer software is frequently applied for this type of analysis. The computational anatomy toolbox (CAT12) for SPM, which offers a fast and easy-to-use alternative approach, was recently made available. METHODS: In this study, we compared region of interest (ROI)-wise CT estimations of the surface-based FreeSurfer 6 (FS6) software and the volume-based CAT12 toolbox for SPM using 44 elderly healthy female control subjects (HC)...
May 15, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29749671/combined-evaluation-of-noncontrast-ct-aspects-and-ct-angiography-collaterals-improves-detection-of-large-infarcts-in-proximal-artery-occlusive-stroke
#16
Farhad Mehrkhani, Olvert A Berkhemer, Charles B L M Majoie, Mohammad Mansouri, Zahra Karimi, Michael H Lev, Albert J Yoo
BACKGROUND AND PURPOSE: Imaging may identify patients with very large infarcts who are unlikely to benefit from intra-arterial therapy. Although computed tomography (CT) is widely used, it suffers from poor sensitivity. We sought to evaluate whether combined evaluation of noncontrast CT (NCCT) and CT angiography (CTA) collaterals would improve the detection of large infarcts. METHODS: All patients with anterior circulation proximal artery occlusion and baseline CT, CTA, and magnetic resonance imaging (MRI) performed were identified...
May 11, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29749664/the-role-of-neuroimaging-in-the-determination-of-brain-death
#17
Derek MacDonald, Brandie Stewart-Perrin, Jai Jai Shiva Shankar
BACKGROUND AND PURPOSE: Brain death determination (BDD) is primarily a clinical diagnosis, where death is defined as the permanent loss of brainstem function. In scenarios where clinical examinations are inaccurate, ancillary imaging tests are required. The choice of ancillary imaging test is variable, but the common denominator for all of them is to establish a lack of cerebral blood flow. The purpose of this study was to compare the diagnostic accuracy and interrater reliability of different ancillary imaging tests used for BDD...
May 11, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29749662/high-resolution-nerve-ultrasound-and-electrophysiological-findings-in-restless-legs-syndrome
#18
K Pitarokoili, M Fels, A Kerasnoudis, L Toenges, R Gold, M-S Yoon
BACKGROUND AND PURPOSE: Restless legs syndrome (RLS) is a multifactorial network disorder of a sensorimotor system extending from dopaminergic and glutamatergic cerebral structures to the spinal neurons and peripheral nerves. The role of peripheral nerve damage in the causality and severity progression for RLS patients remains unclear. METHODS: We performed a clinical and epidemiological study on a cohort of 34 RLS patients focusing on RLS risk factors and disease severity...
May 11, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29749661/fingolimod-s-impact-on-mri-brain-volume-measures-in-multiple-sclerosis-results-from-ms-mrius
#19
Robert Zivadinov, Jennie Medin, Nasreen Khan, Jonathan R Korn, Niels Bergsland, Michael G Dwyer, Tanuja Chitnis, Robert T Naismith, Enrique Alvarez, Peter Kinkel, Stanley Cohan, Samuel F Hunter, Diego Silva, Bianca Weinstock-Guttman
BACKGROUND AND PURPOSE: Evidence is needed to understand the effect of fingolimod on slowing down brain atrophy progression in multiple sclerosis (MS) patients in clinical practice. We investigated the effect of fingolimod on brain atrophy in MS patients with active disease (clinically and/or magnetic resonance imaging [MRI]) versus no evidence of active disease (NEAD). METHODS: MS and clinical outcome and MRI in the United States (MS-MRIUS) is a multicenter, retrospective study that included 590 relapsing-remitting MS patients, who initiated fingolimod, and were followed for a median of 16 months...
May 11, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29727515/microv-technology-to-improve-transcranial-color-coded-doppler-examinations
#20
Giovanni Malferrari, Giuseppe Pulito, Attilia Maria Pizzini, Nicola Carraro, Giorgio Meneghetti, Enzo Sanzaro, Patrizio Prati, Antonio Siniscalchi, Daniela Monaco
The purpose of this review is to provide an update on technology related to Transcranial Color Coded Doppler Examinations. Microvascularization (MicroV) is an emerging Power Doppler technology which can allow visualization of low and weak blood flows even at high depths, thus providing a suitable technique for transcranial ultrasound analysis. With MicroV, reconstruction of the vessel shape can be improved, without any overestimation. Furthermore, by analyzing the Doppler signal, MicroV allows a global image of the Circle of Willis...
May 4, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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