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Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging

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https://www.readbyqxmd.com/read/28736910/longitudinal-mr-spectroscopy-shows-altered-metabolism-in-traumatic-brain-injury
#1
Andrew A Maudsley, Varan Govind, Gaurav Saigal, Stuart G Gold, Leo Harris, Sulaiman Sheriff
BACKGROUND AND PURPOSE: Brain trauma is known to result in heterogeneous patterns of tissue damage and altered neuronal and glial metabolism that evolve over time following injury; however, little is known on the longitudinal evolution of these changes. In this study, magnetic resonance spectroscopic imaging (MRSI) was used to map the distributions of altered metabolism in a single subject at five time points over a period of 28 months following injury. METHODS: Magnetic resonance imaging and volumetric MRSI data were acquired in a subject that had experienced a moderate traumatic brain injury (Glasgow Coma Scale 13) at five time points, from 7 weeks to 28 months after injury...
July 23, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28722300/digital-subtraction-angiography-dynavision-in-pretreatment-planning-for-embolization-of-dural-arterio-venous-fistulas
#2
Alex Botsford, Jai Jai Shiva Shankar
BACKGROUND AND PURPOSE: We have found DSA-Dynavision with multiplanar reconstruction very helpful in understanding the complex anatomy and planning of treatment of carotico-cavernous fistulas. The purpose of our study was to examine whether using DSA-Dynavision in pretreatment planning results in better outcome after endovascular treatment of dural arterio-venous fistulas (dAVFs). METHODS: Patients with dAVF treated with endovascular embolization were retrospectively identified from our interventional neuroradiology database...
July 19, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28722240/an-mri-hyperintense-acute-reperfusion-marker-is-related-to-elevated-peripheral-monocyte-count-in-acute-ischemic-stroke
#3
Zurab Nadareishvili, Marie Luby, Richard Leigh, Jignesh Shah, John K Lynch, Amie W Hsia, Richard T Benson, Lawrence L Latour
BACKGROUND AND PURPOSE: Blood-brain barrier (BBB) disruption detected on magnetic resonance imaging (MRI) in acute ischemic stroke as a hyperintense acute reperfusion marker (HARM) is associated with upregulation of matrix metalloproteinase-9 (MMP-9). Although activated leukocytes, including monocytes, are the main source of MMPs, limited data exist to support relationship between leukocyte activation and BBB disruption in patients with acute ischemic stroke. The goal of this study is to investigate the relationship between neutrophils, lymphocytes, and monocytes with BBB disruption detected as HARM (+) in patients with acute ischemic stroke...
July 19, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28722200/the-gibraltar-sign-an-anatomic-landmark-for-predicting-transverse-sinus-dominance-laterality-on-conventional-mri
#4
David R Pettersson, Joel D McLouth, Benjamin Addicott, Jeffrey M Pollock, Ramon F Barajas
BACKGROUND AND PURPOSE: Physiologic asymmetry of transverse sinus (TS) caliber is common and can lead to misinterpretation of magnetic resonance venography (MRV) studies of the brain. This retrospective study assesses the ability of multiple anatomic features on axial noncontrast T1-weighted images (T1WIs) of the brain to predict congenital TS dominance. METHODS: One hundred consecutively acquired combined MRI-MRV studies of the brain were reviewed. On noncontrast axial T1WI, each reviewer measured (1) inclination of the groove for the superior sagittal sinus (SSS), (2) angulation of the posterior falx, (3) laterality of the SSS flow void, and (4) laterality of the inferior-most occipital lobe...
July 19, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28718993/role-of-fdg-pet-mri-fdg-pet-ct-and-dynamic-susceptibility-contrast-perfusion-mri-in-differentiating-radiation-necrosis-from-tumor-recurrence-in-glioblastomas
#5
Mojgan Hojjati, Chaitra Badve, Vasant Garg, Curtis Tatsuoka, Lisa Rogers, Andrew Sloan, Peter Faulhaber, Pablo R Ros, Leo J Wolansky
BACKGROUND AND PURPOSE: To compare the utility of quantitative PET/MRI, dynamic susceptibility contrast (DSC) perfusion MRI (pMRI), and PET/CT in differentiating radiation necrosis (RN) from tumor recurrence (TR) in patients with treated glioblastoma multiforme (GBM). METHODS: The study included 24 patients with GBM treated with surgery, radiotherapy, and temozolomide who presented with progression on imaging follow-up. All patients underwent PET/MRI and pMRI during a single examination...
July 18, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28670797/cerebral-pulsatility-index-is-elevated-in-patients-with-elevated-right-atrial-pressure
#6
Shouri Lahiri, Konrad H Schlick, Matthew M Padrick, Brenda Rinsky, Nestor Gonzalez, Heather Jones, Stephan A Mayer, Patrick D Lyden
BACKGROUND AND PURPOSE: Extracerebral venous congestion can precipitate intracranial hypertension due to obstruction of cerebral blood outflow. Conditions that increase right atrial pressure, such as hypervolemia, are thought to increase resistance to jugular venous outflow and contribute to cerebro-venous congestion. Cerebral pulsatility index (CPI) is considered a surrogate marker of distal cerebrovascular resistance and is elevated with intracranial hypertension. Thus, we sought to test the hypothesis that elevated right atrial pressure is associated with increased CPI compared to normal right atrial pressure...
July 3, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28661060/decreased-glutamate-levels-in-patients-with-amnestic-mild-cognitive-impairment-an-slaser-proton-mr-spectroscopy-and-pib-pet-study
#7
Burcu Zeydan, Dinesh K Deelchand, Nirubol Tosakulwong, Timothy G Lesnick, Orhun H Kantarci, Mary M Machulda, David S Knopman, Val J Lowe, Clifford R Jack, Ronald C Petersen, Gülin Öz, Kejal Kantarci
BACKGROUND AND PURPOSE: Glutamate levels may be informative about the declining neuronal health in the central nervous system. We used an advanced proton MR spectroscopy ((1) H-MRS) protocol composed of semi-localization by adiabatic selective refocusing (sLASER) localization and FAST(EST)MAP shimming for detection of alterations in brain glutamate concentrations in patients with amnestic mild cognitive impairment. METHODS: Participants with amnestic mild cognitive impairment (n = 14; median age = 80) and age- and sex-matched clinically normal controls (n = 32; median age = 79) from the population-based Mayo Clinic Study of Aging were recruited prospectively to the 3T single-voxel (1) H-MRS study that examined metabolite changes in the posterior cingulate gyri...
June 29, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28654166/lesions-in-the-splenium-of-the-corpus-callosum-on-mri-in-children-a-review
#8
Marinos Kontzialis, Bruno P Soares, Thierry A G M Huisman
A wide variety of conditions may involve the splenium of the corpus callosum on magnetic resonance imaging in children. A single cause may present with different patterns of splenial involvement, and multiple diseases may have similar imaging findings. Keeping this limitation in mind, the goal of this text is to assist in the diagnostic process of pediatric neurological diseases that are characterized by prominent involvement of the splenium of the corpus callosum on imaging. The various pathologies will be reviewed and categorized based on etiology, reversibility, and pattern of additional or associated findings...
June 27, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28574665/simultaneous-multislice-based-5-minute-lumbar-spine-mri-protocol-initial-experience-in-a-clinical-setting
#9
Maria G Longo, Joana Fagundes, Susie Huang, William Mehan, Thomas Witzel, Himanshu Bhat, Keith Heberlein, Bruce R Rosen, Daniel Rosenthal, Ramon G Gonzalez, Pamela W Schaefer, Otto Rapalino
BACKGROUND AND PURPOSE: Previous studies have used parallel imaging (PI) techniques to decrease spine magnetic resonance imaging (MRI) protocol acquisition times. Recently developed MRI sequences allow even faster acquisitions. Our purpose was to develop a lumbar spine MRI protocol using PI with GRAPPA (generalized autocalibrating partially parallel acquisition) and a simultaneous multislice (SMS)-based sequence and to evaluate its diagnostic performance compared to a standard lumbar spine MRI protocol...
June 2, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28574627/ct-versus-mr-techniques-in-the-detection-of-cervical-artery-dissection
#10
Uta Hanning, Peter B Sporns, Meilin Schmiedel, Erich B Ringelstein, Walter Heindel, Heinz Wiendl, Thomas Niederstadt, Ralf Dittrich
BACKGROUND: Spontaneous cervical artery dissection (sCAD) is an important etiology of juvenile stroke. The gold standard for the diagnosis of sCAD is convential angiography. However, magnetic resonance imaging (MRI)/MR angiography (MRA) and computed tomography (CT)/CT angiography (CTA) are frequently used alternatives. New developments such as multislice CT/CTA have enabled routine acquisition of thinner sections with rapid imaging times. The goal of this study was to compare the capability of recent developed 128-slice CT/CTA to MRI/MRA to detect radiologic features of sCAD...
June 2, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28569398/sodium-mri-of-t1-high-signal-intensity-in-the-dentate-nucleus-due-to-gadolinium-deposition-in-multiple-sclerosis
#11
Philipp Eisele, Simon Konstandin, Kristina Szabo, Melissa Ong, Frank Zöllner, Lothar R Schad, Stefan O Schoenberg, Achim Gass
BACKGROUND AND PURPOSE: Recently, several studies reported increased signal intensity (SI) of the dentate nucleus (DN) on unenhanced T1-weighted magnetic resonance imaging (MRI) as a possible consequence of multiple applications of gadolinium-based contrast agents. The aim of this study was to investigate with sodium ((23) Na) MRI possible tissue abnormalities of the DN in multiple sclerosis (MS) patients. METHODS: Sodium and conventional MRI were performed on a clinical 3T scanner...
June 1, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28543774/spectral-signal-density-of-carotid-plaque-using-dual-energy-computed-tomography
#12
Exequiel Reynoso, Gastón A Rodriguez-Granillo, Carlos Capunay, Alejandro Deviggiano, Francisco Meli, Patricia Carrascosa
BACKGROUND AND PURPOSE: Plaque characterization using virtual monochromatic imaging derived from dual-energy computed tomography (CT) angiography requires the determination of normal signal density values of each plaque component. We sought to explore the signal density values of carotid plaque components using dual-energy compared to conventional single-energy CT angiography (CTA), and to establish the energy level with the largest differences between plaque components. METHODS: The present prospective study involved consecutive patients referred for carotid artery evaluation by CTA...
May 25, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28524459/prognostic-role-of-conventional-and-dynamic-contrast-enhanced-mri-in-optic-pathway-gliomas
#13
Nutchawan Jittapiromsak, Ping Hou, Ho-Ling Liu, Jia Sun, John M Slopis, T Linda Chi
BACKGROUND AND PURPOSE: The natural history of optic pathway glioma (OPG) is highly variable and unpredictable. We present a pilot study of the prognostic role of conventional and dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) in the evaluation of OPG. METHODS: We retrospectively reviewed 17 patients with 20 pretreatment OPG lesions who underwent conventional and DCE MRI between January 2010 and December 2016. Conventional MRI was evaluated for enhancement pattern, cystic component, optic nerve tortuosity, optic nerve dural ectasia, and optic nerve perineural thickening...
May 19, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28524416/diagnostic-ultrasound-of-the-vagus-nerve-in-patients-with-diabetes
#14
Eman A Tawfik, Francis O Walker, Michael S Cartwright, Rana A El-Hilaly
BACKGROUND AND PURPOSE: Autonomic neuropathy is a serious and common complication of diabetes mellitus. The vagus nerve is the longest autonomic nerve, and may be affected in diabetes as a part of generalized neuropathy. Our objective was to assess for possible sonographic changes of the vagus nerve in diabetic patients. METHODS: The vagus nerve was bilaterally scanned in 20 healthy volunteers and 54 patients with diabetes in the axial plane at the lateral neck...
May 19, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28514045/contrast-extravasation-versus-hemorrhage-after-thrombectomy-in-patients-with-acute-stroke
#15
Vivek Yedavalli, Steffen Sammet
BACKGROUND AND PURPOSE: Intra-arterial recanalization postprocedural imaging in stroke patients can result in diagnostic complications due to hyperdensities on noncontrast computed tomography (CT), which may represent either contrast extravasation or intracranial hemorrhage. If these lesions are hemorrhage, then they are risk factors becoming symptomatic, which, if not distinguished, can alter clinical management. We investigate the effects of iodinated contrast on postprocedural magnetic resonance imaging (MRI) and prevalence of equivocal imaging interpretations of postprocedural extravasated contrast versus hemorrhage while identifying protocol pitfalls...
May 17, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28488811/resolution-of-occlusive-carotid-artery-thrombus-treated-with-anticoagulation-as-demonstrated-on-duplex-ultrasonography
#16
Laura Stein, John W Liang, Jesse Weinberger
BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid atherosclerosis. Identification of nonatherosclerotic thrombus as the cause of the carotid occlusive disease can obviate the need for an interventional procedure, and resolution of thrombus can be monitored with B-mode duplex ultrasonography. METHODS: We reviewed 3 patients treated on The Mount Sinai Hospital Stroke Unit with anticoagulation for nonatherosclerotic carotid thrombi and followed with serial Doppler ultrasonogrpahy for resolution of thrombus...
May 10, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28488804/three-dimensional-shape-and-surface-features-distinguish-multiple-sclerosis-lesions-from-nonspecific-white-matter-disease
#17
Braeden D Newton, Katy Wright, Mandy D Winkler, Francesca Bovis, Masaya Takahashi, Ivan E Dimitrov, Maria Pia Sormani, Marco C Pinho, Darin T Okuda
BACKGROUND AND PURPOSE: There remains a need to further refine the ability of clinicians to differentiate multiple sclerosis (MS) from other disease etiologies. Here, we illustrate the value of 3-dimensional (3D) geometric shape and surface lesion characteristics between disease states. METHODS: Standardized 3-Tesla 3D brain magnetic resonance imaging studies were performed on enrolled MS and nonspecific white matter (NSWM) patients. Focal supratentorial lesions were identified, reconstructed using maximum intensity projection, manually segmented, and 3D printed...
May 10, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28464417/a-novel-semiautomated-pipeline-to-measure-brain-atrophy-and-lesion-burden-in-multiple-sclerosis-a-long-term-comparative-study
#18
Tomas Uher, Jan Krasensky, Manuela Vaneckova, Lukas Sobisek, Zdenek Seidl, Eva Havrdova, Niels Bergsland, Michael G Dwyer, Dana Horakova, Robert Zivadinov
BACKGROUND AND PURPOSE: Lesion burden and brain volume changes are frequent end points in research but nowadays are becoming important in the clinical practice of multiple sclerosis (MS). The objective of this study was to investigate the correlation between magnetic resonance imaging (MRI) measures obtained by in-house developed ScanView software and commonly used volumetric techniques for assessment of T2 lesion and whole brain volumes and their changes. METHODS: Together 3,340 MRI scans from 209 patients after first demyelinating event suggestive of MS, 181 relapsing-remitting MS patients and 43 controls were analyzed...
May 2, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28464368/leptomeningeal-enhancement-at-7t-in-multiple-sclerosis-frequency-morphology-and-relationship-to-cortical-volume
#19
Daniel M Harrison, Kevin Y Wang, Julie Fiol, Kerry Naunton, Walter Royal, Jun Hua, Izlem Izbudak
BACKGROUND AND PURPOSE: Perform an investigation of the frequency and distribution of leptomeningeal enhancement on postgadolinium magnetization-prepared FLAIR (MPFLAIR) in multiple sclerosis (MS) on 7 Tesla (7T) MRI and to relate this finding to measures of brain structure and lesion volumes. METHODS: Twenty-nine participants with MS underwent 7T MRI of the brain. Three healthy volunteers (HVs) were scanned for comparison. Areas of postcontrast leptomeningeal enhancement were identified...
May 2, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28066971/the-association-between-diffusion-mri-defined-infarct-volume-and-nihss-score-in-patients-with-minor-acute-stroke
#20
Shadi Yaghi, Charlotte Herber, Amelia K Boehme, Howard Andrews, Joshua Z Willey, Sara K Rostanski, Matthew Siket, Mahesh V Jayaraman, Ryan A McTaggart, Karen L Furie, Randolph S Marshall, Ronald M Lazar, Bernadette Boden-Albala
BACKGROUND: Prior studies have shown a correlation between the National Institutes of Health Stroke Scale (NIHSS) and stroke volume on diffusion weighted imaging (DWI); data are more limited in patients with minor stroke. We sought to determine the association between DWI lesion(s) volume and the (1) total NIHSS score and (2) NIHSS component scores in patients with minor stroke. METHODS: We included all patients with minor stroke (NIHSS 0-5) enrolled in the Stroke Warning Information and Faster Treatment study...
July 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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