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Cleft Palate-craniofacial Journal

Muhaini Yakob, H Yang Rafidah, M Gu, Y Yang
OBJECTIVE:   To test the reliability of the modified Huddart-Bodenham (MHB) numerical scoring system and its agreement with the GOSLON Yardstick categorization for assessing the dental arch relationships in unilateral cleft lip and palate (UCLP) cases. DESIGN:   A retrospective study. SETTING:   Faculty of Dentistry, The University of Hong Kong. PATIENTS:   Forty-one nonsyndromic UCLP consecutive patients attending the Joint Cleft Lip/Palate Clinic at Faculty of Dentistry in the University of Hong Kong were selected...
January 16, 2017: Cleft Palate-craniofacial Journal
Zhigang Liang, Jinfeng Yao, Philip K T Chen, Cangshang Zheng, Jiying Yang
OBJECTIVE:   The objective of this study was to assess the efficacy of presurgical nasoalveolar molding (PNAM) on long-term nasal symmetry and shaping after primary cheiloplasty in patients with unilateral complete cleft lip/palate (UCL/P). DESIGN:   This was a two-group, parallel, prospective, randomized clinical trial. SETTING:   The setting for this study was the Chang Gung Craniofacial Center in Taoyuan, Taiwan. PATIENTS:   Patients were divided into one of the following two groups: infants with UCL/P who underwent PNAM (PNAM group, n = 42) and infants with UCL/P who did not undergo PNAM (non-PNAM group, n = 42)...
January 13, 2017: Cleft Palate-craniofacial Journal
Ari M Wes, Nadine Paul, Patrick A Gerety, Nancy Folsom, Jordan Swanson, Jesse A Taylor, Mark H Weinstein
PURPOSE:   Patient follow-up after cleft missions is imperative if we are to critically assess the quality of care provided in these settings. The adoption of mobile telephones among disadvantaged families abroad may enable such an undertaking in a cost-effective manner. This project aimed to assess the efficacy of cellular phone-based follow-up in a developing country following a cleft mission to Thailand. METHODS:   Changing Children's Lives Inc. performed a cleft surgical mission to Udon Thani, Thailand, in January 2013...
January 13, 2017: Cleft Palate-craniofacial Journal
Joseph S Khouri, Melisande J McCheyne, Clinton S Morrison
INTRODUCTION:   Many societies and organizations are using social media to reach their target audience. The extent to which parents of patients with craniofacial anomalies use social media has yet to be determined. The goal of this study is to characterize and describe the use of social media by the parents of children with cleft lip and palate as it pertains to the care of their child. MATERIALS AND METHODS:   Parents or guardian of all patients presenting for initial consultation regarding a child's congenital cleft anomaly were contacted by phone or mail to complete a survey regarding their use of social media vis-à-vis their child's cleft anomaly...
January 13, 2017: Cleft Palate-craniofacial Journal
Paige Miranda, Badam Enkhmandakh, Dashzeveg Bayarsaihan
OBJECTIVES:   The aim of this study is to define the candidate target genes for TFII-I and AP2α regulation in neural crest progenitor cells. DESIGN:   The GTF2I and GTF2IRD1 genes encoding the TFII-I family of transcription factors are prime candidates for the Williams-Beuren syndrome, a complex multisystem disorder characterized by craniofacial, skeletal, and neurocognitive deficiencies. AP2α, a product of the TFAP2A gene, is a master regulator of neural crest cell lineage...
January 13, 2017: Cleft Palate-craniofacial Journal
Gemma C Sharp, Evie Stergiakouli, Jonathan Sandy, Caroline Relton
No abstract text is available yet for this article.
January 13, 2017: Cleft Palate-craniofacial Journal
Andreas Kehrer, Tim H J Nijhuis, Pál Pesthy, Sten Willemsen, René Poublon, Jacques J J N M van der Meulen
OBJECTIVE:   Our aim was to analyze our technique of a modified rotational advancement in conjunction with buccal mucosal grafts (BMGs) in a subgroup of severe cleft cases. DESIGN:   A retrospective clinical and photographic evaluation was conducted. Columella angle (CA) and tip projection (TPR) served as instruments in a photometric analysis. SETTING:   Academic university hospital and specialized craniofacial cleft center. PATIENTS:   At the time of the secondary rhinoplasty, 61 cleft patients were included, all 17 years or older...
January 10, 2017: Cleft Palate-craniofacial Journal
Thomas J Sitzman, Alexander C Allori, Damir B Matic, Stephen P Beals, David M Fisher, Thomas D Samson, Jeffrey R Marcus, Raymond Tse, The Americleft Task Force Surgeon Subgroup
OBJECTIVE:   Oronasal fistula is an important complication of cleft palate repair that is frequently used to evaluate surgical quality, yet reliability of fistula classification has never been examined. The objective of this study was to determine the reliability of oronasal fistula classification both within individual surgeons and between multiple surgeons. DESIGN:   Using intraoral photographs of children with repaired cleft palate, surgeons rated the location of palatal fistulae using the Pittsburgh Fistula Classification System...
December 29, 2016: Cleft Palate-craniofacial Journal
Tim Bressmann, Bojana Radovanovic, Susan Harper, Paula Klaiman, David Fisher, Gajanan V Kulkarni
Manyspeakers with cleft palate develop atypical consonant productions, especially for pressure consonants such as plosives, fricatives, and affricates. The present study investigated the nature of nasal sound errors. The participants were eight female and three male speakers with cleft palate between the ages of 6 to 20. Speakers were audio-recorded, and midsagittal tongue movement was captured with ultrasound. The speakers repeated vowel-consonant-vowel with the vowels /α/, /i/, and /u/ and the alveolar and velar nasal consonants /n/ and /...
December 29, 2016: Cleft Palate-craniofacial Journal
Chen Yan, He Deng-Qi, Chen Li-Ya, Yang Mang, Yang Ke-Hu
BACKGROUND:   A series of epidemiological studies were conducted to investigate the association between transforming growth factor alpha (TGFA) polymorphism and nonsyndromic cleft lip and/or palate (CL/P) risk, but the findings remain conflicting. The present meta-analysis summarizes the association between the TGFA Taq I polymorphisms and nonsyndromic CL/P risk. METHODS:   We searched PubMed, EMBASE, Web of Science, and Chinese Biomedical Literature databases from their inception to May 1, 2015...
December 21, 2016: Cleft Palate-craniofacial Journal
Kimberly M Daniels, Emily Yang Yu, Rebecca G Maine, Yin Heng, Li Yang, Bing Shi, D Scott Corlew, William Y Hoffman, George A Gregory
BACKGROUND:   Humanitarian surgical organizations provide palatoplasties for patients without access to surgical care. Few organizations have evaluated the outcomes of these trips. This study evaluates the palatal fistula rate in patients from two cohorts in rural China and one in the United States. METHODS:   This study compared the odds of fistula formation among three cohorts whose palates were repaired between 2005 and 2009. One cohort included 97 Chinese patients operated on by teams from the United States and Canada under the auspices of Resurge International...
December 21, 2016: Cleft Palate-craniofacial Journal
Natasha M Wickert, Karen W Y Wong Riff, Mark Mansour, Christopher R Forrest, Timothy E E Goodacre, Andrea L Pusic, Anne F Klassen
OBJECTIVE:   The aim of this systematic review was to identify patient-reported outcome (PRO) instruments used in research with children/youth with conditions associated with facial differences to identify the health concepts measured. DESIGN:   MEDLINE, EMBASE, CINAHL, and PsycINFO were searched from 2004 to 2016 to identify PRO instruments used in acne vulgaris, birthmarks, burns, ear anomalies, facial asymmetries, and facial paralysis patients. We performed a content analysis whereby the items were coded to identify concepts and categorized as positive or negative content or phrasing...
December 21, 2016: Cleft Palate-craniofacial Journal
Peter A Mossey, Julian Little, Regine Steegers-Theunissen, Anne Molloy, Borut Peterlin, William C Shaw, Candice Johnson, David R FitzPatrick, Paola Franceschelli, Michele Rubini
BACKGROUND:   Nonsyndromic cleft lip with or without cleft palate (nsCL±P) and nonsyndromic cleft palate (nsCP) are caused by a combination of genetic and environmental risk factors. We investigated gene-environment and gene-gene joint effects in a large multicenter study of case-parent triads. METHODS:   The nsCL±P or nsCP triads were recruited in 11 European countries between 2001 and 2005. We collected DNA samples from infants and from their mothers and fathers, and mothers completed a questionnaire on exposures, including smoking and folic acid supplement use during pregnancy...
December 20, 2016: Cleft Palate-craniofacial Journal
F J Mulder, D G M Mosmuller, H C W de Vet, C M Mouës, C C Breugem, A B Mink van der Molen, J P W Don Griot
OBJECTIVE:   To develop a reliable and easy-to-use method to assess the nasolabial appearance of 18-year-old patients with unilateral cleft lip and palate (CLP). DESIGN:   Retrospective analysis of nasolabial aesthetics using a 5-point ordinal scale and newly developed photographic reference scale: the Cleft Aesthetic Rating Scale (CARS). Three cleft surgeons and 20 medical students scored the nasolabial appearance on standardized frontal photographs. SETTING:   Medical Center X...
December 20, 2016: Cleft Palate-craniofacial Journal
Janani A Raveendran, Jerry W Chao, Gary F Rogers, Michael J Boyajian
Congenital macrostomia, or Tessier number 7 cleft, is a rare craniofacial anomaly. We present a unique patient with bilateral macrostomia that consisted of a "double" transverse cleft on the left side and a single transverse cleft on the right side. A staged reconstructive approach was used to repair the "double" left-sided clefts. This staged technique produced a satisfactory aesthetic and functional outcome.
December 13, 2016: Cleft Palate-craniofacial Journal
Supakit Peanchitlertkajorn, Ana Mercado, John Daskalogiannakis, Ronald Hathaway, Kathleen Russell, Gunvor Semb, William Shaw, Manish Lamichane, Jennifer Fessler, Ross E Long
OBJECTIVE:   To compare dental arch relationship and craniofacial morphology of patients with CUCLP in pre-adolescence from five cleft centers including a center using NAM. DESIGN:   Retrospective cohort study. SETTING:   Five cleft centers in North America. PATIENTS:   One hundred eighty-two subjects with repaired CUCLP from the five cleft centers participated in the craniofacial form study. One hundred forty-eight subjects from four of the five centers participated in the dental arch relationship study...
November 1, 2016: Cleft Palate-craniofacial Journal
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Cleft Palate-craniofacial Journal
Sarah Castick, Rachael-Anne Knight, Debbie Sell
OBJECTIVE:   To investigate the reliability of ordinal versus visual analogue scaling (VAS) ratings for perceptual judgments of nasal resonance, nasal airflow, understandability, and acceptability in speakers with cleft palate. DESIGN:   Within-subjects comparative study. SETTING:   Multisite. PARTICIPANTS:   Five specialist speech and language therapists from U.K. Regional Cleft Centres. OUTCOME MEASURES:   Participants rated 30 audio speech samples obtained from the Speech and Language Therapy archives of Great Ormond Street Hospital...
January 2017: Cleft Palate-craniofacial Journal
Jack Yu
No abstract text is available yet for this article.
January 2017: Cleft Palate-craniofacial Journal
S Alex Rottgers, Phillip Gallo, James Gilbert, Zoe Macisaac, James Cray, Darren M Smith, Mark P Mooney, Joseph Losee, Sandeep Kathju, Gregory Cooper
OBJECTIVE:   Fusion of the cranial sutures is thought to depend on signaling among perisutural tissues. Mapping regional variations in gene expression would improve current models of craniosynostosis. Laser capture microdissection (LCM) isolates discrete cell populations for gene expression analysis. LCM has rarely been used in the study of mineralized tissue. This study sought to evaluate the potential use of LCM for mapping of regional gene expression within the cranial suture. DESIGN:   Coronal sutures were isolated from 10-day-old wild-type and craniosynostotic (CS) New Zealand White rabbits, and LCM was used to isolate RNA from the sutural ligament (SL), osteogenic fronts (OF), dura mater, and periosteum...
January 2017: Cleft Palate-craniofacial Journal
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