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Cleft Palate-craniofacial Journal

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https://www.readbyqxmd.com/read/28140670/speech-in-adults-treated-for-unilateral-cleft-lip-and-palate-long-term-follow-up-after-one-or-two-stage-palate-repair
#1
Staffan Morén, Maria Mani, Stålhammar Lilian, Per Åke Lindestad, Mats Holmström
OBJECTIVE:   To evaluate speech in adults treated for unilateral cleft lip and palate with one-stage or two-stage palate closure and compare the speech of the patients with that of a noncleft control group. DESIGN:   Cross-sectional study with long-term follow-up. PARTICIPANTS/SETTING:   All unilateral cleft lip and palate patients born from 1960 to 1987 and treated at Uppsala University Hospital, Sweden, were invited (n = 109). Participation rate was 67% (n = 73) at a mean of 35 years after primary surgery...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28094562/effects-of-bisphosphonate-administration-on-cleft-bone-graft-in-a-rat-model
#2
Nicole Cheng, Juyoung Park, Jeffrey Olson, Taewoo Kwon, Deborah Lee, Rachel Lim, Sandy Ha, Reuben Kim, Xinli Zhang, Kang Ting, Sotirios Tetradis, Christine Hong
OBJECTIVE:   Bone grafts in patients with cleft lip and palate can undergo a significant amount of resorption. The aim of this study was to investigate the effects of bisphosphonates (BPs) on the success of bone grafts in rats. DESIGN:   Thirty-five female 15-week-old Fischer F344 Inbred rats were divided into the following experimental groups, each receiving bone grafts to repair an intraoral CSD: (1) Graft/saline: systemic administration of saline and (2) systemic administration of zoledronic acid immediately following surgery (graft/BP/T0), (3) 1 week postoperatively (graft/BP/T1), and (4) 3 weeks postoperatively (graft/BP/T2)...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27996298/genetic-interactions-in-nonsyndromic-orofacial-clefts-in-europe-eurocran-study
#3
Peter A Mossey, Julian Little, Regine Steegers-Theunissen, Anne Molloy, Borut Peterlin, William C Shaw, Candice Johnson, David R FitzPatrick, Paola Franceschelli, Michele Rubini
BACKGROUND:   Nonsyndromic cleft lip with or without cleft palate (nsCL±P) and nonsyndromic cleft palate (nsCP) are caused by a combination of genetic and environmental risk factors. We investigated gene-environment and gene-gene joint effects in a large multicenter study of case-parent triads. METHODS:   The nsCL±P or nsCP triads were recruited in 11 European countries between 2001 and 2005. We collected DNA samples from infants and from their mothers and fathers, and mothers completed a questionnaire on exposures, including smoking and folic acid supplement use during pregnancy...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27723380/oculoauriculofrontonasal-dysplasia-syndrome-with-additional-clinical-features
#4
Turan Tunc, Adem Polat, Bilal Altan, Abdul Kerim Yapici, Mehmet Saldir, Sabahattin Sari, Erkan Sari, Yalcin Bayram, Muhitdin Eski
Oculo-auriculo-vertebral spectrum and frontonasal dysplasia are two well-known examples of dysmorphology syndromes. Oculoauriculofrontonasal syndrome (OAFNS) is a clinical entity involving the characteristics of both OAVS and FND and is thought to be a result of the abnormal development of structures in the first and the second branchial arches, including the abnormal morphogenesis of maxillary processes. Herein we report a case of OAFNS with cliteral hypertrophy, premaxillary teeth, and inguinal hernia, features not previously reported in the literature...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27723379/a-case-report-of-absent-epiglottis-in-children-with-nager-syndrome-its-impact-on-swallowing
#5
Sok Yan Tay, Woei Shyang Loh, Thiam Chye Lim
OBJECTIVE:   This clinical report is the first literature report exploring the issues of an absent epiglottis in children diagnosed with Nager syndrome. Absent epiglottis has previously been described in children with Pierre Robin sequence and other syndromes. CONCLUSION:   The function of the epiglottis and its contribution to swallowing has always been debated. In this article and from our literature review, we felt that absent epiglottis possibly contributed to the aspiration risk and may partly explain the long-term feeding issues in these children despite corrective surgeries...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27723378/microstructured-%C3%AE-tricalcium-phosphate-putty-versus-autologous-bone-for-repair-of-alveolar-clefts-in-a-goat-model
#6
Nard G Janssen, Adrianus P de Ruiter, Wouter M M T van Hout, Vincent van Miegem, Debby Gawlitta, Florence Barrère-de Groot, Gert J Meijer, Antoine J W P Rosenberg, Ronald Koole
For the first time it was demonstrated that an osteoinductive calcium phosphate-based putty is effective in the restoration of complex maxillofacial defects. In these defects, adequate mechanical confinement by multiple bony walls and osteoconduction from multiple surfaces are usually lacking. This study compares the efficacy of a microstructured beta-tricalcium phosphate (β-TCP) putty with autologous bone for the repair of alveolar cleft defects. A total of 10 Dutch milk goats were operated on in a split-mouth study design in which two-wall bony alveolar clefts were created and successively repaired with autologous bone (the gold standard) at one side and β-TCP putty at the other...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27632764/optimizing-safety-of-iliac-bone-harvest-using-an-acumed-drill-a-simulated-radiographic-study-of-100-patients
#7
John T Stranix, Daniel Cuzzone, Catherine Ly, Nicole Topilow, Christopher M Runyan, Justin Ream, Roberto L Flores
OBJECTIVE:   To determine the potential risk of visceral injury during Acumed drill iliac crest cancellous bone graft harvest. DESIGN:   Radiographic iliac crest anatomic analysis with simulated drill course to measure cancellous bone available for harvest and proximity of vulnerable pelvic structures. SETTING:   Single institution, tertiary care university hospital. PATIENTS AND PARTICIPANTS:   One hundred pelvic computed tomography scans performed on children 8 to 12 years old without traumatic or neoplastic pathology...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27632762/prevalence-of-renal-and-cervical-vertebral-anomalies-in-patients-with-isolated-microtia-and-or-aural-atresia
#8
Shane Zim, Janet Lee, Brian Rubinstein, Craig Senders
OBJECTIVE:   The objective of this study was to determine whether patients with isolated microtia or aural atresia have an increased prevalence of renal or cervical vertebral anomalies. DESIGN:   The study design was a retrospective medical record review. SETTING:   The setting was the following four distinct institutions: an urban tertiary care children's hospital, two urban academic medical centers, and a staff-model health maintenance organization...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27632760/survey-of-parent-experiences-in-prenatal-visits-for-infants-with-cleft-lip-and-palate
#9
Matthew R Greives, Casey L Anderson, Riley A Dean, Michelle L Scerbo, Irene L Doringo, Michael W Bebbington, John F Teichgraeber
OBJECTIVE:   The purpose of this study was to identify the factors that influence the parent's choice of cleft team/surgeon. DESIGN:   A 10-question survey was used to elucidate factors that influenced parents in choosing their cleft surgeon. No identifiers of the origin of the study were used to improve parent objectivity. SETTING:   The setting for this study was an online survey. PARTICIPANTS:   Participants in this study were the parents of children who were born with cleft lip and/or palate...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27618615/bending-reality-adventures-in-global-plastic-surgeryschultz-rc-morgan-hill-california-bookstand-publishing-isbn-1618635549-pp-243-87-illustrations-softcover-2013-15-95
#10
https://www.readbyqxmd.com/read/27618614/simonart-s-band-its-effect-on-cleft-classification-and-recommendations-for-standardized-nomenclature
#11
Sanjay Naran, Richard E Kirschner, Lindsay Schuster, Osama Basri, Matthew Ford, Jesse Goldstein, Lorelei Grunwaldt, Mark P Mooney, Joseph E Losee
OBJECTIVE:   Accurate classification of cleft lip plays an important role in communication, treatment planning, and comparison of outcomes across centers. Although there is reasonable consensus in defining cleft types, the presence of Simonart's band can make classification challenging. Our objective was to survey cleft care providers to determine what all consider to be Simonart's band, how its presence effects cleft lip classification, and to provide recommendations for standardized nomenclature...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27537492/preliminary-study-to-determine-the-reference-plane-of-patients-with-a-unilateral-cleft-lip-and-palate
#12
Na-Ri Kim, Soo-Byung Park, Sang Min Shin, Yong-Seok Choi, Seong-Sik Kim, Woo-Sung Son, Yong-Il Kim
OBJECTIVE:   The objective of this study was to determine the three-dimensional midsagittal reference planes for unilateral cleft lip and palate (UCLP) patients that can be easily applied in a clinical setting. DESIGN:   This was a retrospective analysis. PATIENTS:   There were 35 UCLP patients (25 men, 10 women; 28.1 ± 6.9 years old) in this study. METHODS:   With landmark's three-dimensional coordinates obtained from cone-beam computed tomography, the symmetric midsagittal reference planes were calculated by applying the ordinary Procrustes superimposition method using the original and mirror images...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27518405/sleep-outcomes-in-children-with-single-suture-craniosynostosis-compared-with-unaffected-controls
#13
Baiyang Sun, Yona K Cloonan, Brent R Collett, Matthew L Speltz
OBJECTIVE:   To compare risk for sleep-disordered breathing between children with and without single-suture craniosynostosis. PARTICIPANTS:   A total of 184 children with single-suture craniosynostosis and 184 controls. MAIN OUTCOME MEASURES:   Parent reported sleep-disordered breathing-related symptoms. RESULTS:   Current sleep problems were reported in 19% of patients with single-suture craniosynostosis and 14% of controls (adjusted odds ratio = 1...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27505181/hypertelorism-and-orofacial-clefting-revisited-an-anthropometric-investigation
#14
Seth M Weinberg, Elizabeth J Leslie, Jacqueline T Hecht, George L Wehby, Frederic W B Deleyiannis, Lina M Moreno, Kaare Christensen, Mary L Marazita
OBJECTIVE:   Since the 1960s, multiple studies have reported a tendency toward hypertelorism in individuals with nonsyndromic orofacial clefts (OFCs). However, the association between specific cleft types and increased interorbital distance has been inconsistent. Using three-dimensional (3D) surface imaging, we tested whether different forms of clefting showed evidence of increased interorbital distance. METHODS:   Intercanthal and outercanthal distances and intercanthal indices were calculated from 3D facial surface images of 287 individuals with repaired OFCs...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27458649/hearing-loss-in-children-with-craniofacial-microsomia
#15
Ryan M Mitchell, Babette S Saltzman, Susan J Norton, Robert G Harrison, Carrie L Heike, Daniela V Luquetti, Kathleen C Y Sie
OBJECTIVE:   To evaluate the association between craniofacial phenotype and hearing loss in children with craniofacial microsomia. DESIGN:   Retrospective cohort study. SETTING:   Tertiary care children's hospital. PATIENTS:   Individuals with craniofacial microsomia. MAIN OUTCOME MEASURES:   Ear-specific audiograms and standardized phenotypic classification of facial characteristics...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27441702/three-dimensional-analysis-of-nasal-symmetry-following-primary-correction-of-unilateral-cleft-lip-nasal-deformity
#16
Olivia E Linden, Helena O Taylor, Sivabalan Vasudavan, Margaret E Byrne, Curtis K Deutsch, John B Mulliken, Stephen R Sullivan
OBJECTIVE:   To evaluate nasal symmetry using three-dimensional photogrammetry following primary tip rhinoplasty with or without an internal splint in patients with unilateral complete cleft lip/palate. DESIGN:   We captured three-dimensional images of patients with unilateral complete cleft lip/palate who underwent nasolabial repair by rotation-advancement of the lip and primary tip rhinoplasty, either with or without an internal resorbable splint, and normal control subjects...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27441700/evaluation-of-ventilation-tube-placement-and-long-term-audiologic-outcome-in-children-with-cleft-palate
#17
Elissa Kim, Melissa D Kanack, Milan D Dang-Vu, Daniela Carvalho, Marilyn C Jones, Amanda A Gosman
OBJECTIVE:   The purpose of this study was to assess the effect of ventilation tube (VT) placement on long-term hearing outcomes in children with cleft palate. STUDY DESIGN:   Case series with chart review. SETTING:   Genetic and dysmorphology database at Rady Children's Hospital-San Diego (RCHSD). PATIENTS:   Children with cleft palate diagnosis who underwent surgery at RCHSD between 1995 and 2002. MAIN OUTCOME MEASURE:   The primary outcome studied was hearing acuity at 10 years of age...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27441697/reliability-of-the-swag-the-standardized-way-to-assess-grafts-method-for-alveolar-bone-grafting-in-patients-with-cleft-lip-and-palate
#18
Kathleen Russell, Ross E Long, John Daskalogiannakis, Ana Mercado, Ronald Hathaway, Gunvor Semb, William Shaw
OBJECTIVE:   The objective of this study was to test a new method, a Standardized Way to Assess Grafts (SWAG), to rate alveolar bone graft (ABG) outcomes for patients with cleft lip and palate. DESIGN:   This was a retrospective comparison using the SWAG scale. SETTING:   This study took place in four cleft palate centers with different treatment protocols. METHODS:   A total of 160 maxillary occlusal radiographs taken 3 to 18 months post-ABG for sequentially treated patients with cleft lip and palate were assessed using the SWAG scale...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27356087/familial-recurrence-of-3mc-syndrome-in-consanguineous-families-a-clinical-and-molecular-diagnostic-approach-with-review-of-the-literature
#19
Olivia K Gardner, Karla Haynes, Daniela Schweitzer, Alexis Johns, William P Magee, Mark M Urata, Pedro A Sanchez-Lara
We report four individuals from two unrelated consanguineous families with 3MC syndrome. In the first family, chromosome microarray data revealed that the two affected sisters, born to first-cousin parents, shared a unique homozygous C-terminal deletion in the COLEC11 gene. Two affected brothers from a second family, also born to first-cousin parents, shared a region of homozygosity that included the second gene known to cause the 3MC syndrome, MASP1. We discuss the diagnostic approach of craniofacial disorders born to consanguineous parents and highlight a literature search and reference a helpful dysmorphology solution powered by FDNA (Facial Dysmorphology Novel Analysis) technology...
November 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27243667/primary-cleft-lip-and-palate-repair-in-assam-india-does-preoperative-anthropometric-analysis-help-identify-patients-with-increased-surgical-risk-in-a-clinically-prescreened-population
#20
Mairin A Jerome, Justin Gillenwater, Donald R Laub, Turner Osler, Anna Y Allan, Carolina Restrepo, Alex Campbell
OBJECTIVE:   To compare anthropometric z-scores with incidence of post-operative complications for patients undergoing primary cleft lip or palate repair. DESIGN:   This was a retrospective observational analysis of patients from a surgical center in Assam, India, and includes a cohort from a single surgical mission completed before the opening of the center. SETTING:   Patients included in the study underwent surgery during an Operation Smile mission before the opening of Operation Smile's Guwahati Comprehensive Cleft Care Center in Guwahati, India...
November 2017: Cleft Palate-craniofacial Journal
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