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Cleft Palate-craniofacial Journal

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https://www.readbyqxmd.com/read/28140671/comparison-of-three-methods-of-rating-nasolabial-appearance-in-cleft-lip-and-palate
#1
Sylwia A Fudalej, Dries Desmedt, Ewald Bronkhorst, Piotr S Fudalej
OBJECTIVE:   To investigate which of three methods of rating nasolabial appearance-esthetic index, visual analogue scale (VAS), or numerical scale with reference photographs-is optimal. DESIGN:   Experimental study. SETTING:   Radboud University Medical Centre, The Netherlands and University of Bern, Switzerland. SUBJECTS AND METHODS:   Cropped photographs of 60 patients with complete unilateral cleft lip and palate (mean age = 10...
January 31, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28140670/speech-in-adults-treated-for-unilateral-cleft-lip-and-palate-long-term-follow-up-after-one-or-two-stage-palate-repair
#2
Staffan Morén, Maria Mani, Stålhammar Lilian, Per Åke Lindestad, Mats Holmström
OBJECTIVE:   To evaluate speech in adults treated for unilateral cleft lip and palate with one-stage or two-stage palate closure and compare the speech of the patients with that of a noncleft control group. DESIGN:   Cross-sectional study with long-term follow-up. PARTICIPANTS/SETTING:   All unilateral cleft lip and palate patients born from 1960 to 1987 and treated at Uppsala University Hospital, Sweden, were invited (n = 109). Participation rate was 67% (n = 73) at a mean of 35 years after primary surgery...
January 31, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28140669/surgical-repositioning-of-the-premaxilla-using-a-minimally-invasive-endonasal-approach
#3
Nicolas E Sierra, Ada Ferrer-Fuertes, Bárbara Salazar-Perez, Gui-Youn Cho-Lee, Carles Martí-Pages, Alejandro Rivera-Baró, Josep Rubio Palau, Eloy M García-Diez
OBJECTIVE:   The aim of this study was to evaluate a technique for the surgical repositioning of the premaxilla using a minimally invasive endonasal approach. DESIGN:   Retrospective review of clinical records. SETTING:   Tertiary care, University Hospital, pediatric maxillofacial surgery unit. PATIENTS:   Twenty-one patients (12 boys and 9 girls), ages ranging from 6 to 21 years, with BCLP+A and premaxillary malposition (PM)...
January 31, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28140668/a-family-with-craniofrontonasal-syndrome-the-first-report-of-familial-cases-of-craniofrontonasal-syndrome-with-bilateral-cleft-lip-and-palate
#4
Yoshikazu Inoue, Yoshiaki Sakamoto, Masanori Sugimoto, Hidehito Inagaki, Hiroko Boda, Masafumi Miyata, Hideteru Kato, Hiroki Kurahashi, Takayuki Okumoto
Craniofrontonasalsyndrome (CFNS) is a very rare genetic disorder, the common physical malformations of which include coronal synostosis, widely spaced eyes, clefting of the nasal tip, and various skeletal anomalies. Mutations of EFNB1, which encodes a member of the ephrin family of transmembrane ligands for Eph receptor tyrosine kinases, is the cause of CFNS. Although familial CFNS cases have been reported, no studies in the literature describe familial cases of CFNS expressing bilateral cleft lip and palate...
January 31, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28140667/incidence-of-palatal-fistula-at-time-of-secondary-alveolar-cleft-reconstruction
#5
Vikram A Shankar, Alison Snyder-Warwick, Gary B Skolnick, Albert S Woo, Kamlesh B Patel
OBJECTIVE:   We aim to establish consistent time points for evaluating palatal fistula incidence to standardize reporting practices and clarify prospective literature. DESIGN:   An institutional retrospective chart review was conducted on 76 patients with unilateral or bilateral complete cleft lip and palate who underwent secondary alveolar bone grafting between 2006 and 2015. MAIN OUTCOME MEASURES:   Early fistula incidence rates were reported prior to maxillary expansion, and late fistula rates were reported at the time of alveolar bone grafting...
January 31, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28135115/molecular-analysis-of-ephrin-a4-and-ephrin-b1-in-a-rabbit-model-of-craniosynostosis-likely-exclusion-as-the-loci-of-origin
#6
Gwen M Taylor, Gregory M Cooper, Joseph E Losee, Mark P Mooney, James Gilbert
Craniosynostosis (CS) has a prevalence of approximately 1 in every 2000 live births and is characterized by the premature fusion of one or more cranial sutures. Failure to maintain the cell lineage boundary at the coronal suture is thought to be involved in the pathology of some forms of CS. The Ephrin family of receptor tyrosine kinases consists of membrane-bound receptors and ligands that control cell patterning and the formation of developmental boundaries. Mutations in the ephrin A4 (EFNA4) and ephrin B1 (EFNB1) ligands have been linked to nonsyndromic CS and craniofrontonasal syndrome, respectively, in patient samples...
January 30, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28099037/letter-to-the-editor
#7
J C Roldán, John L Spolyar
No abstract text is available yet for this article.
January 18, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28094564/secondary-cleft-nasolabial-deformities-a-new-classification-system-for-evaluation-and-surgical-revision
#8
Ghassan Abu Sittah, Odette Abou Ghanem, Usama Hamdan, Paul Ramia, Elias Zgheib
INTRODUCTION:   Secondary or residual cleft lip and nasal deformities following primary unilateral or bilateral cleft lip repair are common. Many classification systems have been proposed to describe congenital cleft lip and palate deformities before repair. This article proposes a one-of-a-kind classification system for residual cleft deformities and describes its application to 136 cleft lip revision cases from cleft outreach missions worldwide. METHODS:   Patients' demographics and deformities were classified preoperatively, and a database of the classification was created...
January 17, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28094563/dental-arch-relationships-and-reverse-headgear-effects-in-southern-chinese-patients-with-unilateral-cleft-lip-and-palate-a-retrospective-study
#9
Yang Rafidah Hassan, Kwan Lok Tse, Balvinder Singh Khambay, Wing Kit Wong, Min Gu, Yanqi Yang
OBJECTIVE:   To evaluate the severity of the dental arch relationships and the treatment outcomes of reverse headgear (RHG) in southern Chinese patients with unilateral cleft lip and palate (UCLP). DESIGN:   A retrospective study. SETTING:   Faculty of Dentistry, The University of Hong Kong. PATIENTS:   Thirty-eight UCLP patients with complete records. Among them, 14 were later treated with RHG (RHG group) and 24 were under review (non-RHG group) before definitive orthodontic or in conjunction with orthognathic surgery...
January 17, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28094562/effects-of-bisphosphonate-administration-on-cleft-bone-graft-in-a-rat-model
#10
Nicole Cheng, Juyoung Park, Jeffrey Olson, Taewoo Kwon, Deborah Lee, Rachel Lim, Sandy Ha, Reuben Kim, Xinli Zhang, Kang Ting, Sotirios Tetradis, Christine Hong
OBJECTIVE:   Bone grafts in patients with cleft lip and palate can undergo a significant amount of resorption. The aim of this study was to investigate the effects of bisphosphonates (BPs) on the success of bone grafts in rats. DESIGN:   Thirty-five female 15-week-old Fischer F344 Inbred rats were divided into the following experimental groups, each receiving bone grafts to repair an intraoral CSD: (1) Graft/saline: systemic administration of saline and (2) systemic administration of zoledronic acid immediately following surgery (graft/BP/T0), (3) 1 week postoperatively (graft/BP/T1), and (4) 3 weeks postoperatively (graft/BP/T2)...
January 17, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28092164/comparing-modified-huddart-bodenham-scoring-system-and-goslon-yardstick-to-assess-dental-arch-relationships-in-unilateral-cleft-lip-and-palate-patients
#11
Muhaini Yakob, H Yang Rafidah, M Gu, Y Yang
OBJECTIVE:   To test the reliability of the modified Huddart-Bodenham (MHB) numerical scoring system and its agreement with the GOSLON Yardstick categorization for assessing the dental arch relationships in unilateral cleft lip and palate (UCLP) cases. DESIGN:   A retrospective study. SETTING:   Faculty of Dentistry, The University of Hong Kong. PATIENTS:   Forty-one nonsyndromic UCLP consecutive patients attending the Joint Cleft Lip/Palate Clinic at Faculty of Dentistry in the University of Hong Kong were selected...
January 16, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28085515/effect-of-presurgical-nasoalveolar-molding-on-nasal-symmetry-in-unilateral-complete-cleft-lip-palate-patients-after-primary-cheiloplasty-without-concomitant-nasal-cartilage-dissection-early-childhood-evaluation
#12
Zhigang Liang, Jinfeng Yao, Philip K T Chen, Cangshang Zheng, Jiying Yang
OBJECTIVE:   The objective of this study was to assess the efficacy of presurgical nasoalveolar molding (PNAM) on long-term nasal symmetry and shaping after primary cheiloplasty in patients with unilateral complete cleft lip/palate (UCL/P). DESIGN:   This was a two-group, parallel, prospective, randomized clinical trial. SETTING:   The setting for this study was the Chang Gung Craniofacial Center in Taoyuan, Taiwan. PATIENTS:   Patients were divided into one of the following two groups: infants with UCL/P who underwent PNAM (PNAM group, n = 42) and infants with UCL/P who did not undergo PNAM (non-PNAM group, n = 42)...
January 13, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28085514/a-sustainable-model-for-patient-follow-up-following-an-international-cleft-mission-a-proof-of-concept
#13
Ari M Wes, Nadine Paul, Patrick A Gerety, Nancy Folsom, Jordan Swanson, Jesse A Taylor, Mark H Weinstein
PURPOSE:   Patient follow-up after cleft missions is imperative if we are to critically assess the quality of care provided in these settings. The adoption of mobile telephones among disadvantaged families abroad may enable such an undertaking in a cost-effective manner. This project aimed to assess the efficacy of cellular phone-based follow-up in a developing country following a cleft mission to Thailand. METHODS:   Changing Children's Lives Inc. performed a cleft surgical mission to Udon Thani, Thailand, in January 2013...
January 13, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28085513/-cleft-the-use-of-social-media-amongst-parents-of-infants-with-clefts
#14
Joseph S Khouri, Melisande J McCheyne, Clinton S Morrison
INTRODUCTION:   Many societies and organizations are using social media to reach their target audience. The extent to which parents of patients with craniofacial anomalies use social media has yet to be determined. The goal of this study is to characterize and describe the use of social media by the parents of children with cleft lip and palate as it pertains to the care of their child. MATERIALS AND METHODS:   Parents or guardian of all patients presenting for initial consultation regarding a child's congenital cleft anomaly were contacted by phone or mail to complete a survey regarding their use of social media vis-à-vis their child's cleft anomaly...
January 13, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28085512/tfii-i-and-ap2%C3%AE-co-occupy-the-promoters-of-key-regulatory-genes-associated-with-craniofacial-development
#15
Paige Miranda, Badam Enkhmandakh, Dashzeveg Bayarsaihan
OBJECTIVES:   The aim of this study is to define the candidate target genes for TFII-I and AP2α regulation in neural crest progenitor cells. DESIGN:   The GTF2I and GTF2IRD1 genes encoding the TFII-I family of transcription factors are prime candidates for the Williams-Beuren syndrome, a complex multisystem disorder characterized by craniofacial, skeletal, and neurocognitive deficiencies. AP2α, a product of the TFAP2A gene, is a master regulator of neural crest cell lineage...
January 13, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28085511/epigenetics-and-orofacial-clefts-a-brief-introduction
#16
Gemma C Sharp, Evie Stergiakouli, Jonathan Sandy, Caroline Relton
No abstract text is available yet for this article.
January 13, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28072550/rotational-advancement-in-cleft-nose-rhinoplasty-buccal-mucosal-grafts-serve-as-a-powerful-tool
#17
Andreas Kehrer, Tim H J Nijhuis, Pál Pesthy, Sten Willemsen, René Poublon, Jacques J J N M van der Meulen
OBJECTIVE:   Our aim was to analyze our technique of a modified rotational advancement in conjunction with buccal mucosal grafts (BMGs) in a subgroup of severe cleft cases. DESIGN:   A retrospective clinical and photographic evaluation was conducted. Columella angle (CA) and tip projection (TPR) served as instruments in a photometric analysis. SETTING:   Academic university hospital and specialized craniofacial cleft center. PATIENTS:   At the time of the secondary rhinoplasty, 61 cleft patients were included, all 17 years or older...
January 10, 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28033026/reliability-of-oronasal-fistula-classification
#18
Thomas J Sitzman, Alexander C Allori, Damir B Matic, Stephen P Beals, David M Fisher, Thomas D Samson, Jeffrey R Marcus, Raymond Tse, The Americleft Task Force Surgeon Subgroup
OBJECTIVE:   Oronasal fistula is an important complication of cleft palate repair that is frequently used to evaluate surgical quality, yet reliability of fistula classification has never been examined. The objective of this study was to determine the reliability of oronasal fistula classification both within individual surgeons and between multiple surgeons. DESIGN:   Using intraoral photographs of children with repaired cleft palate, surgeons rated the location of palatal fistulae using the Pittsburgh Fistula Classification System...
December 29, 2016: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28033025/production-of-two-nasal-sounds-by-speakers-with-cleft-palate
#19
Tim Bressmann, Bojana Radovanovic, Susan Harper, Paula Klaiman, David Fisher, Gajanan V Kulkarni
Manyspeakers with cleft palate develop atypical consonant productions, especially for pressure consonants such as plosives, fricatives, and affricates. The present study investigated the nature of nasal sound errors. The participants were eight female and three male speakers with cleft palate between the ages of 6 to 20. Speakers were audio-recorded, and midsagittal tongue movement was captured with ultrasound. The speakers repeated vowel-consonant-vowel with the vowels /α/, /i/, and /u/ and the alveolar and velar nasal consonants /n/ and /...
December 29, 2016: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/28001102/transforming-growth-factor-alpha-taq-i-polymorphisms-and-nonsyndromic-cleft-lip-and-or-palate-risk-a-meta-analysis
#20
Chen Yan, He Deng-Qi, Chen Li-Ya, Yang Mang, Yang Ke-Hu
BACKGROUND:   A series of epidemiological studies were conducted to investigate the association between transforming growth factor alpha (TGFA) polymorphism and nonsyndromic cleft lip and/or palate (CL/P) risk, but the findings remain conflicting. The present meta-analysis summarizes the association between the TGFA Taq I polymorphisms and nonsyndromic CL/P risk. METHODS:   We searched PubMed, EMBASE, Web of Science, and Chinese Biomedical Literature databases from their inception to May 1, 2015...
December 21, 2016: Cleft Palate-craniofacial Journal
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