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Cleft Palate-craniofacial Journal

Agneta Karsten, Metaxia Sideri, Meropi Spyropoulos
OBJECTIVE: To examine and compare the prevalence of morphologic anomalies of the upper cervical vertebrae in Swedish children with nonsyndromic cleft lip and/or palate to Swedish children without cleft. DESIGN: Retrospective study on lateral cephalograms. SETTING: Division of Orthodontics, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden. PATIENTS: The cleft group consisted of 325 children (150 girls and 175 boys) born with nonsyndromic cleft lip and/or palate (mean age: 11...
November 1, 2018: Cleft Palate-craniofacial Journal
Diana S Jodeh, Mitchell Buller, S Alex Rottgers
BACKGROUND: Presurgical infant orthopedics (PSIO) techniques were introduced to improve the outcomes achieved when treating children with complete cleft lip and palate. The effect of PSIO on the incidence of postoperative fistulae has never been reliably demonstrated. We conducted a meta-analysis to assess the effectiveness of PSIO in reducing postoperative fistulas in patients with complete cleft lip and palate. METHODS: A search of the PubMed and Embase databases was performed to identify relevant articles that included primary palate repairs of patients with unilateral or bilateral complete clefts, reported the incidence of postoperative fistulae, and explicitly stated if PSIO was used...
October 31, 2018: Cleft Palate-craniofacial Journal
Qiang Zhang, Yuanyi Yue, Bei Shi, Zhengwei Yuan
OBJECTIVE: Cleft lip and palate (CLP) is the most common human cranial and maxillofacial birth defect. The aim of this bibliometric analysis was to provide an overview of the development of CLP-related research. METHOD: Cleft lip and palate-related studies published from 2000 to 2017 were retrieved from the Science Citation Index Expanded core database. Publication date, journal, authors, first authors, keywords, and citations were extracted and quantitatively analyzed using Bibliographic Item Co-Occurrence Matrix Builder software...
October 30, 2018: Cleft Palate-craniofacial Journal
Syed Altaf Hussain, Charanya Vijayakumar
BACKGROUND: Maxillary advancement with a rigid external distractor (RED) II is a commonly performed procedure for correcting midface hypoplasia. While there are various methods of anchoring the osteotomized maxillary segment to the halo device, the looped transpyriform wire is the simplest and most cost-effective. However, a common complication with this is the cutting through of the stainless steel traction wire across the pyriform buttress during distraction. The patient with cleft undergoing midface distraction is particularly vulnerable since the force needed for distraction is higher due to scarring from previous operations...
October 30, 2018: Cleft Palate-craniofacial Journal
James R Gilbert, Gwen M Taylor, Joseph E Losee, Mark P Mooney, Gregory M Cooper
OBJECTIVE: Craniosynostosis (CS) involves the premature fusion of one or more cranial sutures. We work with a naturally occurring rabbit model of CS with an undefined etiology. Known causes of coronal CS were evaluated to identify potential associations with CS in the rabbit. DESIGN: Candidate genes were sequenced in control New Zealand White (NZW) rabbits (n = 4) and synostotic NZW rabbits (n = 4). Variants were identified by alignment using Clustal Omega. OUTCOME MEASURES: Single nucleotide variants (SNVs) were classified according to phenotypic associations and predicted impact on protein structure...
October 28, 2018: Cleft Palate-craniofacial Journal
Jennie C Lacour, Lori McBride, Hugo St Hilaire, Gerhard S Mundinger, Michael Moses, Jessica Koon, Jairo I Torres, Yves Lacassie
We report 2 cases of mandibulofacial dysostosis with microcephaly (MFDM) with different and novel de novo mutations in the elongation factor Tu GTP binding domain containing 2 gene. Both cases were initially thought to have alternative disorders but were later correctly diagnosed through whole-exome sequencing. These cases expand upon our knowledge of the phenotypic spectrum in patients with MFDM, which will aid in defining the full phenotype of this disorder and increase awareness of this condition.
October 21, 2018: Cleft Palate-craniofacial Journal
Brian L Chang, Jason W Yu, Elena Nikonova, David W Low, Jesse A Taylor, Oksana Jackson
OBJECTIVE: The purpose of this study was to characterize intraoperative palatal lengthening with the modified Furlow cleft palatal repair and to determine whether lengthening correlated with preoperative cleft width, cleft type, or operating surgeon. DESIGN: Retrospective study. SETTING: Academic tertiary care pediatric hospital. PATIENTS: One hundred eighty pediatric patients undergoing primary or secondary palatoplasty using the Furlow technique...
October 11, 2018: Cleft Palate-craniofacial Journal
David J Zajac
Posterior nasal fricatives (PNFs) are unusual articulations that occur in some children with and without cleft palate. The etiology of PNFs is unclear. A young girl with repaired cleft palate is described who exhibited inconsistent obligatory nasal turbulence during production of stops at 2 years of age. At 3 years of age, she exhibited various phonological processes and used PNFs to replace sibilants and affricates. Pressure-flow testing showed a relatively small velopharyngeal area during production of stops...
October 10, 2018: Cleft Palate-craniofacial Journal
Alexander Morzycki, Joshua Gillis, Michael Bezuhly
BACKGROUND: Establishing continuity of the cutaneous roll is critical to cleft lip repair. Unfortunately, this landmark can be difficult to appreciate depending on the patient's skin tone, surgical lighting, or preexisting scar. SOLUTION: When applied to the lip, dilute povidone-iodine solution beads off the cutaneous roll and dry vermilion, clearly defining these structures. What We Do: We use dilute povidone-iodine solution not only to prep the lip but to delineate landmarks critical to cleft lip repair...
October 10, 2018: Cleft Palate-craniofacial Journal
Natalie Loomans, Oona Decombel, Klara Goethals, Maurice Y Mommaerts
OBJECTIVE: This study aimed to compare differences in the maxillary transverse dimension following cleft repair using 2 protocols involving a 2-staged palatal closure with similar timing but different techniques. DESIGN: Retrospective study. Two matched study samples, each containing 10 patients. SETTING: Cleft center A is a university hospital. Cleft Center B is a general teaching hospital. PATIENTS: Patients with cleft lip alveolus and palate (CLAP) were matched by cleft type, gender, age, and palatal morphology at the age of 1 month...
October 10, 2018: Cleft Palate-craniofacial Journal
Tulasi Nayak, Krishnamurthy Bonanthaya, Renu Parmar, Pritham N Shetty, Dipesh D Rao
OBJECTIVE: To evaluate and compare early maxillary growth in 2 groups of patients with repaired bilateral cleft lip and palate (BCLP) who had and had not received nasoalveolar molding (NAM) therapy in infancy. HYPOTHESIS: Nasoalveolar molding does not have any effect on maxillomandibular growth at the early mixed dentition period. DESIGN: Retrospective study. PATIENTS: The study group consisted of forty-two 7-year-old patients with BCLP-20 in the NAM group and 22 in the no-NAM group...
September 27, 2018: Cleft Palate-craniofacial Journal
Thomas J Sitzman, Adam C Carle, Pamela C Heaton, Michael A Helmrath, Maria T Britto
OBJECTIVE: To identify child-, surgeon- and hospital-specific factors at the time of primary cleft palate repair that are associated with the use of secondary palate surgery. DESIGN: Retrospective cohort study. SETTING: Forty-nine pediatric hospitals. PARTICIPANTS: Children who underwent cleft palate repair between 1998 and 2015. MAIN OUTCOME MEASURE: Time from primary cleft palate repair to secondary palate surgery...
September 24, 2018: Cleft Palate-craniofacial Journal
Travis L Gibson
No abstract text is available yet for this article.
September 13, 2018: Cleft Palate-craniofacial Journal
Christopher J Goodenough, Kathryn T Anderson, Kari E Smith, Robert A Hanfland, Nitin Wadhwa, John F Teichgraeber, Matthew R Greives
OBJECTIVE: To assess the risk of complication in patients undergoing cleft palate repair with congenital cardiac comorbidities in a large, national cohort. DESIGN: Retrospective review. PATIENTS/SETTING: Using the 2012-2014 National Surgical Quality Improvement Program (NSQIP) Pediatric database, patients undergoing cleft palate repair were selected for analysis. Patients with cleft palate repairs were stratified based on the presence or absence congenital cardiac comorbidities...
September 13, 2018: Cleft Palate-craniofacial Journal
Mimis N Cohen
No abstract text is available yet for this article.
September 13, 2018: Cleft Palate-craniofacial Journal
Blaike M Dumas, Ana Nava, Huay-Zong Law, James Smartt, Christopher Derderian, James R Seaward, Alex A Kane, Rami R Hallac
BACKGROUND: As 3-dimensional (3D) printers and models become more widely available and increasingly affordable, surgeons may consider investing in a printer for their own cleft or craniofacial center. To inform surgeons considering adoption of this evolving technology, this study describes one multi-surgeon center's 5-year experience using a 3D printer. METHODS: This study included 3D models printed between October 2012 and October 2017. A 3D Systems ZPrinter 650 was used to create all models...
September 10, 2018: Cleft Palate-craniofacial Journal
Ananda Ise, Camila Menezes, Joao Batista Neto, Saurab Saluja, Julia R Amundson, Hillary Jenny, Ben Massenburg, Isabelle Citron, Nivaldo Alonso
BACKGROUND: In low- and middle-income countries, poor access to care can result in delayed surgical repair of orofacial clefts leading to poor functional outcomes. Even in Brazil, an upper middle-income country with free comprehensive cleft care, delayed repair of orofacial clefts commonly occurs. This study aims to assess patient-perceived barriers to cleft care at a referral center in São Paulo. METHODS: A 29-item questionnaire assessing the barriers to care was administered to 101 consecutive patients (or their guardians) undergoing orofacial cleft surgery in the Plastic Surgery Department in Hospital das Clínicas, in São Paulo, Brazil, between February 2016 and January 2017...
August 28, 2018: Cleft Palate-craniofacial Journal
Kim Bettens, Gillian de Boer, Tim Bressmann, Laura Bruneel, Kristiane Van Lierde
OBJECTIVE: A new approach to classify oral-nasal balance disorders based on instrumental measurements was developed based on linear discriminant analysis (LDA) of nasalance scores of simulated oral-nasal balance disorders by de Boer and Bressmann. The current study aimed to apply the newly developed functions to clinical data to investigate the applicability of this new approach. DESIGN: Retrospective diagnostic accuracy study. SETTING: Tertiary university hospital...
August 22, 2018: Cleft Palate-craniofacial Journal
Julija Radojicic
No abstract text is available yet for this article.
October 2018: Cleft Palate-craniofacial Journal
Filippo Boriani
No abstract text is available yet for this article.
October 2018: Cleft Palate-craniofacial Journal
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