Cynthia M Boyd, Susan M Shetterly, John D Powers, Linda A Weffald, Ariel R Green, Orla C Sheehan, Emily Reeve, Melanie L Drace, Jonathan D Norton, Mahesh Maiyani, Kathy S Gleason, Jennifer K Sawyer, Matthew L Maciejewski, Jennifer L Wolff, Courtney Kraus, Elizabeth A Bayliss
BACKGROUND: Patients, family members, and clinicians express concerns about potential adverse drug withdrawal events (ADWEs) following medication discontinuation or fears of upsetting a stable medical equilibrium as key barriers to deprescribing. Currently, there are limited methods to pragmatically assess the safety of deprescribing and ascertain ADWEs. We report the methods and results of safety monitoring for the OPTIMIZE trial of deprescribing education for patients, family members, and clinicians...
January 2024: Drugs & Aging