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Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society

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https://www.readbyqxmd.com/read/28218999/assessment-of-morbidity-and-mortality-associated-with-eus-guided-fna-for-pancreatic-cystic-lesions-a-system-review-and-meta-analysis
#1
REVIEW
Huiyun Zhu, Fei Jiang, Jianwei Zhu, Yiqi Du, Zhendong Jin, Zhaoshen Li
BACKGROUND AND AIM: With increased availability of imaging technology, detection of pancreatic cystic lesions (PCLs) is on the rise. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) improves the diagnosis accuracy of PCLs. Systematic evaluation of morbidity and mortality associated with EUS-FNA for PCLs has not been performed. We conducted a systematic review and meta-analysis of morbidity and mortality associated with EUS-FNA. METHODS: A literature search for relevant English-language articles was conducted on PubMed and EMBASE databases...
February 20, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28211094/comparison-of-procedural-sequences-in-same-day-painless-bidirectional-endoscopy-a-single-center-prospective-randomized-study
#2
Yan Cao, Jun Yang, Jiao Li, Xin Ao, Kai-Yuan Zhang, Xiao-Chun Shen, Dong-Feng Chen, Chun-Hui Lan
AIMS: To compare the efficacy and safety of esophagogastroduodenoscopy (EGD)-colonoscopy and colonoscopy-EGD sequences for patients subjected to same-day bidirectional endoscopy under remifentanil and propofol sedation. METHOD: A total of 209 eligible outpatients scheduled for diagnostic same-day bidirectional endoscopy between February 16, 2016 and April 30, 2016 were randomly assigned to the EGD-colonoscopy (n=106) and colonoscopy-EGD (n=103) sequence groups. The primary endpoint was the total dose of propofol required for the procedure...
February 17, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28199735/novel-gastric-mucosal-findings-in-association-with-proton-pump-inhibitors
#3
EDITORIAL
Hajime Isomoto, Hiroki Kurumi
Proton pump inhibitors (PPIs) are prescribed worldwide as the treatment of choice for gastroesophageal reflux disease, and are known to exert preventive effects for upper gastrointestinal injuries due to aspirin or non-steroidal anti-inflammatory drugs. On the other hand, the long-term use of PPIs may cause such adverse events as fractures and enteric infections. Recently, they have been associated with mucosal changes including parietal cell protrusions, oxyntic gland dilatations and fundic gland polyps (FGPs)...
February 15, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28190274/team-work-and-cytopathology-molecular-diagnosis-of-solid-pancreatic-lesions-a-review
#4
REVIEW
Carlo Fabbri, Giulia Gibiino, Adele Fornelli, Vincenzo Cennamo, Daniela Grifoni, Michela Visani, Giorgia Acquaviva, Matteo Fassan, Sirio Fiorino, Silvia Giovanelli, Marco Bassi, Stefania Ghersi, Giovanni Tallini, Elio Jovine, Antonio Gasbarrini, Dario de Biase
Pancreatic ductal adenocarcinoma (PDAC) is supposed to become the second leading cancer-associated death by the next years. It is widely accepted that tumorigenesis is linked to specific alterations in key genes and pancreatic neoplasms are some of the best characterized at the genomic level. Recent whole-exome and whole-genome sequencing analyses confirmed that PDAC is frequently characterized by mutations in a set of four genes among the others: KRAS, TP53, CDKN2A/p16, and SMAD4. Sequencing, for example, is the preferable technique available for detecting KRAS mutations, while in situ immunochemistry is the main approach for detecting p53 gene alteration...
February 11, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28182300/endoscopic-double-stenting-for-gastrojejunostomy-anastomotic-and-biliary-obstruction-in-a-patient-with-roux-en-y-reconstruction
#5
Tadahisa Inoue, Kiyoaki Ito, Masashi Yoneda
Although it has been reported that endoscopic double stenting using a self-expandable metallic stent (SEMS) for gastroduodenal and biliary obstruction is useful [1-2], the efficacy and safety of performing double stenting using balloon enteroscopy is uncertain in patients with surgically altered anatomy. We describe a patient who had undergone gastrectomy and then underwent endoscopic double stenting for gastrojejunostomy anastomotic and biliary obstruction. A man in his 50s with a history of having undergone distal gastrectomy with Roux-en-Y reconstruction because of gastric cancer developed gastrojejunostomy anastomotic obstruction due to local anastomotic recurrence and peritoneal dissemination (Fig...
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28181709/combination-therapy-of-over-the-scope-clip-and-covered-metallic-stent-for-refractory-multiple-esophagobronchial-fistulae-and-stenosis
#6
Hirohito Mori, Asadur Rahman, Tsutomu Masaki
Many reports have indicated efficacy of Over-The-Scope-Clip (OTSC) regarding closure of perforation [1, 2]. However, closure of esophagobronchial fistula still remains difficult even by OTSC due to hard tissue of bronchial wall [3]. Combination approaches of OTSC and covered stent were performed to reduce intolerable symptoms. A 59-year-old man was diagnosed with advanced lung cancer with severe dyspnea and massive sputum. This article is protected by copyright. All rights reserved.
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28181708/interventional-eus-where-are-we-headed
#7
REVIEW
Marco J Bruno
EUS is an essential endoscopic tool within the diagnostic and therapeutic armamentarium of gastrointestinal and hepatic diseases. EUS-guided tissue acquisition will develop towards facilitating personalized treatment by obtaining large representative tissue specimens for elaborate immunohistochemical and biomolecular typing of the tumor. Intra-tumoral or intra-vascular delivery of drugs potentially offer many advantages over systemic injection. Intratumoral application of radiofrequency ablation and photodynamic therapy show promise but need to be explored further...
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28181706/efficacy-of-midazolam-versus-propofol-based-sedations-by-non-anesthesiologists-during-therapeutic-endoscopic-retrograde-cholangiopancreatography-in-elderly-patients-over-80-years
#8
Su Jung Han, Tae Hoon Lee, Sang-Heum Park, Young Sin Cho, Yun Nah Lee, Yunho Jung, Hyun Jong Choi, Il-Kwun Chung, Sang-Woo Cha, Jong Ho Moon, Young Deok Cho, Sun-Joo Kim
BACKGROUND: As society ages, the need for ERCP is increasing. This prospective comparative study evaluated the safety and efficacy of midazolam- versus propofol-based sedations by non-anesthesiologists during therapeutic ERCP in patients over 80 years of age. METHODS: A total of 100 patients over 80 years of age who required therapeutic ERCP were enrolled and randomly received midazolam + fentanyl (MF group) or propofol + fentanyl (PF group) sedation. Endoscopic sedation was titrated to a moderate level and performed by trained registered nurses...
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28181704/evaluation-of-the-safety-of-endoscopic-radiofrequency-ablation-for-malignant-biliary-stricture-using-a-digital-peroral-cholangioscope-with-videos
#9
Takeshi Ogura, Saori Onda, Tastsushi Sano, Wataru Takagi, Astushi Okuda, Akira Miyano, Nobu Nishioka, Miyuki Imanishi, Mio Amano, Daisuke Masuda, Kazuhide Higuchi
OBJECTIVES: The clinical impact of catheter based radiofrequency ablation (RFA) under ERCP guidance has been recently reported, however severe adverse events have also been noted. If tumor is not present in the biliary tract, severe adverse events such as perforation or bleeding due to vessel injury around the biliary tract may occur. In addition, the effectiveness of RFA may not be sufficient based solely on radiographic guidance. The aim of this study was to evaluate the actual feasibility of intraductal RFA by peroral cholangioscope (POCS) evaluation before/after RFA...
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28181703/a-rare-cause-of-duodenojejunal-pseudopolyposis-report-of-a-case-of-adult-onset-familial-mediterranean-fever
#10
Motohiro Esaki, Shinichi Kawano, Takayuki Matsumoto
A 39-year-old woman was referred to our hospital for further evaluation of jejunal wall thickening with reactive lymph nodes swelling detected by abdominal CT. During previous 8 months, she had been suffering from periodic epigastric pain along with high fever (38-39°C), which spontaneously regressed within 2-3 days. Anterograde enteroscopy during asymptomatic period showed irregular mucosal folds and scattered inflammatory polyps without active inflammation from the duodenal third portion to the upper jejunum (Fig...
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28181701/primary-gastric-choriocarcinoma-developed-in-a-helicobacter-pylori-negative-patient
#11
Taro Iwatsubo, Noriya Uedo, Kazunobu Ishibashi
A woman in her fifties underwent esophagogastroduodenoscopy, which revealed a whitish large laterally spreading lesion with reddish nodule at the greater curvature (Fig. 1). The patient had no history of Helicobacter pylori (H. pylori) eradication therapy. Anti-H. pylori antibody was negative (<3 U/mL) and no H. pylori-like organism was detected in any of the biopsy specimens. Fundic-gland polyps were seen in the non-atrophic gastric mucosa. No lymph node and distant metastases were found by computed tomography scan...
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28181699/endoscopic-closure-after-intraluminal-surgery
#12
REVIEW
Teppei Akimoto, Osamu Goto, Toshihiro Nishizawa, Naohisa Yahagi
Endoscopic submucosal dissection is established as a curative endoscopic method for gastrointestinal epithelial neoplasms with a high possibility of complete en bloc resection; however, postoperative adverse events of bleeding and delayed perforation remain. To prevent or minimize them, several techniques for endoscopic mucosal closure have been introduced, such as using endoscopic clips, combined use of hemoclips and supplement devices, and specially designed endoscopic suturing devices. Furthermore, endoscopic full-thickness suturing technique for gastrointestinal wall defect has been developed based on the concept in natural orifice transluminal endoscopic surgery and endoscopic full-thickness resection...
February 9, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28171697/eus-guided-tumor-ablation
#13
REVIEW
Sundeep Lakhtakia, Dong-Wan Seo
Real-time guidance of needle advancement has transformed Endoscopic Ultrasound from a diagnostic to an interventional procedure. EUS guided fine needle puncture has application in various interventional procedures (drainage of pseudocyst, biliary intervention, and injection of drugs). Celiac plexus or ganglion neurolysis for pain control is the major current EUS-guided fine-needle injection procedure. Feasibility and safety to accurately position needle devices and/or inject under real time EUS imaging with precise delivery of interventional agent have expanded the use of EUS to ablate tumor...
February 7, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28171691/toward-routine-use-of-nonsteroidal-anti-inflammatory-drugs-for-patients-undergoing-endoscopic-retrograde-cholangiopancreatography
#14
EDITORIAL
Tsuyoshi Hamada, Yousuke Nakai, Hiroyuki Isayama, Kazuhiko Koike
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most widely used pharmacological prevention strategy for post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).(1,2) Experimental data suggest that NSAIDs, a group of inhibitors of PTGS1 (cyclooxygenase-1 or COX-1) and PTGS2 (cyclooxygenase-2 or COX-2), can prevent PEP through inhibition of phospholipase A2 which plays a key role in triggering inflammatory response in the pancreas.(3) Given accumulating evidence from clinical trials, peri-procedural use of rectal NSAIDs is considered as an established strategy for prevention of PEP, at least for patients who have risk factors for PEP including younger age, suspected sphincter of Oddi dysfunction as an indication, and a history of pancreatitis...
February 7, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28171690/endoscopic-submucosal-dissection-of-a-large-neoplastic-lesion-at-ileorectal-anastomosis-in-a-fap-patient
#15
Stefano Sansone, Takeshi Nakajima, Yutaka Saito
Endoscopic submucosal dissection (ESD) may remove gastrointestinal neoplasias even associated with severe fibrosis [1-3]. We report the first case of ESD for a large neoplasia located in the remnant rectum after total colectomy in a patient with familial adenomatous polyposis (FAP). A 19 year old female with FAP underwent total colectomy with ileorectal anastomosis (IRA). Fourteen years later a surveillance endoscopy revealed a 0-Is+IIa lesion, measuring 75mm, occupying the "dog ear" portion of the rectum and involving the IRA (fig 1a-b)...
February 7, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28160344/eus-guided-celiac-plexus-block-and-neurolysis
#16
REVIEW
Ichiro Yasuda, Hsiu-Po Wang
Endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) is widely used for reducing pain originating from upper abdominal organs. It is mainly indicated to treat pancreatic cancer pain, but also to relieve pain due to chronic pancreatitis. Real-time guidance and color Doppler imaging by endoscopic sonography made the procedure easier and safer, resulting in greater pain relief. Currently, two techniques are used for EUS-CPN. The classic approach, known as the central technique, involves injection of a neurolytic agent at the base of the celiac axis...
February 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28160342/diagnostic-efficacy-of-liquid-based-cytology-for-solid-pancreatic-lesion-samples-obtained-with-endoscopic-ultrasound-guided-fine-needle-aspiration-a-propensity-score-matched-analysis
#17
Shinichi Hashimoto, Hiroki Taguchi, Michiyo Higashi, Kazuhito Hatanaka, Toshihiro Fujita, Hiromichi Iwaya, Junichi Nakazawa, Shiho Arima, Yuji Iwashita, Fumisato Sasaki, Yuichiro Nasu, Shuji Kanmura, Akio Ido
OBJECTIVES: There is a paucity of data on the diagnostic efficacy of liquid-based cytology (LBC) for pancreatic samples obtained by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). Using propensity score matching, we retrospectively analyzed the additional diagnostic value of LBC compared to a conventional Papanicolaou smear (CPS) for samples of solid pancreatic lesions obtained via EUS-FNA. METHODS: This cohort study included 126 matched patients who underwent initial EUS-FNA for solid pancreatic lesions between January 2009 and August 2014...
February 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28160332/histopathological-analysis-of-cold-snare-polypectomy-and-its-indication-for-colorectal-polyps-10-14mm-in-diameter
#18
Ryohei Hirose, Naohisa Yoshida, Takaaki Murakami, Kiyoshi Ogiso, Yutaka Inada, Osamu Dohi, Tetsuya Okayama, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Takeshi Ishikawa, Hideyuki Konishi, Yuji Naito, Yasuko Fujita, Mitsuo Kishimoto, Akio Yanagisawa, Yoshito Itoh
BACKGROUND AND AIM: Cold snare polypectomy (CSP) is commonly used for treating colorectal polyps <10 mm in diameter. We evaluated the histopathological and safety of CSP for larger polyps. METHODS: We retrospectively analyzed 1,006 colorectal polyps resected with CSP. The indication for CSP was polyps 2-14 mm that were diagnosed as benign neoplastic polyp by magnifying endoscopy. Various clinicopathological characteristics were analyzed. Multivariate analyses were utilized to determine the independent risk factors for failure of complete CSP resection...
February 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28160331/long-term-outcomes-and-risk-factors-of-biliary-stent-dysfunction-after-endoscopic-double-stenting-for-malignant-biliary-and-duodenal-obstructions
#19
Kazuyuki Matsumoto, Hironari Kato, Koichiro Tsutsumi, Sho Mizukawa, Syuntaro Yabe, Hiroyuki Seki, Yutaka Akimoto, Daisuke Uchida, Takeshi Tomoda, Naoki Yamamoto, Shigeru Horiguchi, Kenji Kuwaki, Hiroyuki Okada
BACKGROUND AND AIMS: Few reports describe the endoscopic double stenting procedure for malignant biliary and duodenal obstructions. We evaluated the clinical outcomes from double stenting, and analyzed the risk factors for biliary stent dysfunction following double stenting. METHODS: Eighty-one patients who underwent endoscopic double stenting for malignant biliary and duodenal obstructions were retrospectively analyzed. We determined the stent dysfunction rate and the biliary stent dysfunction risk factors, and analyzed the endoscopic reintervention results...
February 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28140485/eus-guided-tissue-acquisition-how-to-achieve-excellence
#20
REVIEW
Vikram Bhatia, Shyam Varadarajulu
Endoscopic ultrasound (EUS) guided tissue acquisition is a basic forte of an endosonographer. The multiple skills required to accomplish successful results include not only the puncture itself, but also proper lesion identification, correct puncture sequence, collaboration with the pathologist onsite or remotely, proper handling of the specimens, choosing one or more of cytology, cell-block, and/or tissue core preparation, and lastly deciding the immunohistochemistry (IHC) panels and ancillary tests which may be needed for the case in hand...
January 31, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
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