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Cancer Causes & Control: CCC

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https://www.readbyqxmd.com/read/27900614/trends-in-published-meta-analyses-in-cancer-research-2008-2013
#1
Ximena V Qadir, Mindy Clyne, Tram Kim Lam, Muin J Khoury, Sheri D Schully
In order to capture trends in the contribution of epidemiology to cancer research, we describe an online meta-analysis database resource for cancer clinical and population research and illustrate trends and descriptive detail of cancer meta-analyses from 2008 through 2013. A total of 4,686 cancer meta-analyses met our inclusion criteria. During this 6-year period, a fivefold increase was observed in the yearly number of meta-analyses. Fifty-six percent of meta-analyses concerned observational studies, mostly of cancer risk, more than half of which were genetic studies...
November 29, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27878394/sex-differences-in-the-association-of-obesity-and-colorectal-cancer-risk
#2
Hanseul Kim, Edward L Giovannucci
Epidemiological research has convincingly shown that obesity increases colorectal cancer (CRC) risk, with generally stronger associations observed in men than in women. Evidence from the past several years has demonstrated a divergent pattern between men and women regarding the weight changes throughout life or timing of obesity for CRC risk. For men, weight gain later in life appears to be an important risk factor for CRC that mostly accounts for their generally strong association between adult body mass index and CRC risk...
November 22, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27864712/associations-between-serum-lipids-and-breast-cancer-incidence-and-survival-in-the-e3n-prospective-cohort-study
#3
Mathilde His, Laureen Dartois, Guy Fagherazzi, Anne Boutten, Thierry Dupré, Sylvie Mesrine, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Laure Dossus
PURPOSE: Several mechanistic studies support a role of cholesterol or its metabolites in breast cancer etiology, but associations have been inconsistent in epidemiological studies. In observational studies, possible reverse causation must be accounted for using a prospective design. We investigated prospective associations between pre-diagnostic serum lipid concentrations [total cholesterol (TC), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides], and both breast cancer risk and survival in the E3N cohort study...
November 18, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27832382/diabetes-diabetes-treatment-and-mammographic-density-in-danish-diet-cancer-and-health-cohort
#4
Karsten Buschard, Katrin Thomassen, Elsebeth Lynge, Ilse Vejborg, Anne Tjønneland, My von Euler-Chelpin, Zorana Jovanovic Andersen
PURPOSE: We examined whether diabetes and diabetes treatment are associated with MD in a cohort study of Danish women above age of 50 years. METHODS: Study cohort consisted of 5,644 women (4,500 postmenopausal) who participated in the Danish Diet, Cancer, and Health cohort (1993-1997) and subsequently attended mammographic screening in Copenhagen (1993-2001). We used MD assessed at the first screening after the cohort entry, defined as mixed/dense or fatty. Diabetes diagnoses and diabetes treatments (diet, insulin, or oral antidiabetic agents) were self-reported at the time of recruitment (1993-1997)...
November 10, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27830401/investigating-the-prostate-specific-antigen-body-mass-index-and-age-relationship-is-an-age-bmi-adjusted-psa-model-clinically-useful
#5
Sean Harrison, Kate Tilling, Emma L Turner, J Athene Lane, Andrew Simpkin, Michael Davis, Jenny Donovan, Freddie C Hamdy, David E Neal, Richard M Martin
PURPOSE: Previous studies indicate a possible inverse relationship between prostate-specific antigen (PSA) and body mass index (BMI), and a positive relationship between PSA and age. We investigated the associations between age, BMI, PSA, and screen-detected prostate cancer to determine whether an age-BMI-adjusted PSA model would be clinically useful for detecting prostate cancer. METHODS: Cross-sectional analysis nested within the UK ProtecT trial of treatments for localized cancer...
November 9, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27830400/serum-b6-vitamers-pyridoxal-5-phosphate-pyridoxal-and-4-pyridoxic-acid-and-pancreatic-cancer-risk-two-nested-case-control-studies-in-asian-populations
#6
Joyce Y Huang, Lesley M Butler, Øivind Midttun, Woon-Puay Koh, Per M Ueland, Renwei Wang, Aizhen Jin, Yu-Tang Gao, Jian-Min Yuan
BACKGROUND: Vitamin B6 is an important enzymatic cofactor in pathways relevant for the development of pancreatic cancer. In order to evaluate vitamin B6 as a preventive factor for pancreatic cancer, a biomarker approach is needed to overcome the limitations inherent in self-reported dietary information. METHODS: To determine whether levels of serum B6 vitamers, including pyridoxal 5'-phosphate (PLP), pyridoxal (PL), 4-pyridoxic acid (PA), and the PA/(PLP + PL) ratio (PAr), were associated with risk of pancreatic cancer, two nested case-control studies of 187 incident pancreatic cancer cases and 258 individually matched controls were conducted within two prospective cohorts of 81,501 participants in Shanghai, China, and Singapore...
November 9, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27830399/the-association-of-diabetes-and-obesity-with-prostate-cancer-aggressiveness-among-black-americans-and-white-americans-in-a-population-based-study
#7
Saira Khan, Jianwen Cai, Matthew E Nielsen, Melissa A Troester, James L Mohler, Elizabeth T H Fontham, Laura H Hendrix, Laura Farnan, Andrew F Olshan, Jeannette T Bensen
PURPOSE: Few studies have investigated the role of race in the association of diabetes and obesity with prostate cancer aggressiveness. Here we evaluate the independent association between diabetes and obesity with prostate cancer aggressiveness in White Americans and Black Americans. METHODS: Our cross-sectional, case-only study consisted of 1,058 White Americans and 991 Black Americans from the North Carolina-Louisiana Prostate Cancer (PCaP) project. Diabetes status was determined by self-report...
November 9, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27822586/socio-demographic-and-reproductive-determinants-of-cervical-neoplasia-in-seven-sub-sahara-african-countries
#8
Richard Muwonge, Louise Ngo Mbus, Twalib Ngoma, Charles Gombe Mbalawa, Amadou Dolo, Miraldina da Ganda Manuel, Hassan Nouhou, Marius Nacoulma, Julius Mwaiselage, Moussa Koulibaly, Siné Bayo, Judith Nsonde Malanda, Hugo De Vuyst, Rolando Herrero, Rengaswamy Sankaranarayanan, Namory Keita
BACKGROUND: Since most human papilloma virus (HPV) infections regress without any intervention, HPV is a necessary but may not be a solely sufficient cause of cervical intraepithelial neoplasia (CIN) and cervical cancer. Hence, the influence of cofactors on progression from cervical HPV infection to high-grade CIN and invasive cervical cancer has been a subject of intensive research. OBJECTIVE: We assessed the effect of socio-demographic and sexual reproductive factors on the prevalence of invasive cervical cancer and CIN diagnosed in cross-sectional cervical cancer screening projects carried out in seven sites of different sub-Saharan countries...
November 7, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27817122/nonsteroidal-anti-inflammatory-drugs-statins-and-pancreatic-cancer-risk-a-population-based-case-control-study
#9
Pik Fang Kho, Jonathan Fawcett, Lin Fritschi, Harvey Risch, Penelope M Webb, David C Whiteman, Rachel E Neale
PURPOSE: Studies suggest that aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), and statins may reduce risk of some cancers. However, findings have been conflicting as to whether these agents reduce the risk of pancreatic cancer. METHODS: We used data from the Queensland Pancreatic Cancer Study, a population-based case-control study. In total, 704 cases and 711 age- and sex-matched controls were recruited. Participants completed an interview in which they were asked about history of NSAID and statin use...
November 5, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27812913/geographic-distribution-of-incidence-of-pericardial-and-paratesticular-mesotheliomas-in-the-usa
#10
Sarah J Lowry, Noel S Weiss
PURPOSE: Exposure to asbestos is thought to cause the large majority of pleural mesotheliomas in the USA. It is unknown whether asbestos exposure plays a role in the etiology of rarer forms of mesothelioma, e.g., those located in the pericardium or in the tunica vaginalis of the testis. In order to address this question, we sought to determine whether geographic patterns of incidence of these mesotheliomas have paralleled those of pleural mesotheliomas. METHODS: We used age-adjusted incidence data from the nine populations served by the National Cancer Institute's Surveillance, Epidemiology, and End Results program during 1973-2011...
November 3, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27804058/the-association-of-medication-use-with-clearance-or-persistence-of-oral-hpv-infection
#11
Jennifer O Lam, Elizabeth A Sugar, Ross D Cranston, Kathleen M Weber, Robert D Burk, Dorothy J Wiley, Susheel Reddy, Joseph B Margolick, Howard D Strickler, Alicia Wentz, Lisa Jacobson, Christian L Coles, Jay H Bream, Anne F Rositch, Yingshi Guo, Weihong Xiao, Maura L Gillison, Gypsyamber D'Souza
PURPOSE: Persistent oral human papillomavirus (HPV) infection increases risk for oropharyngeal carcinoma, and people living with HIV have higher rates of oral HPV infection and related cancers. Some prescription medications have immunomodulatory effects, but the impact of medication use on oral HPV natural history is unknown. METHODS: Scope(®) oral rinse-and-gargle samples were collected semi-annually from 1,666 participants and tested for 37 types of oral HPV DNA using PCR; 594 HPV-infected participants with 1,358 type-specific oral HPV infections were identified...
November 1, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27804057/body-size-over-the-life-course-and-the-risk-of-endometrial-cancer-the-california-teachers-study
#12
Pamela L Horn-Ross, Alison J Canchola, Leslie Bernstein, Dennis Deapen, James V Lacey, Eunjung Lee, David O Nelson, Peggy Reynolds
PURPOSE: Obesity is a public health epidemic and a major risk factor for endometrial cancer. Here, we identify key aspects of body size which jointly, over the life-course (since adolescence), are associated with endometrial cancer risk. METHODS: Among 88,142 participants in the California Teachers Study, 887 were diagnosed with invasive type 1 endometrial cancer between 1997-1998 and 2012. Multivariable Cox proportional hazards models provided estimates of hazard rate ratios (HR) and 95% confidence intervals (CI) for endometrial cancer associated with life-course body size phenotypes, which incorporated validated measures...
December 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27804055/childhood-leukemia-and-population-mixing
#13
LETTER
Leo J Kinlen
No abstract text is available yet for this article.
November 1, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27757777/incidence-and-time-trends-of-childhood-lymphomas-findings-from-14-southern-and-eastern-european-cancer-registries-and-the-surveillance-epidemiology-and-end-results-usa
#14
Marios K Georgakis, Maria A Karalexi, Domenic Agius, Luis Antunes, Joana Bastos, Daniela Coza, Anna Demetriou, Nadya Dimitrova, Sultan Eser, Margareta Florea, Anton Ryzhov, Mario Sekerija, Tina Žagar, Anna Zborovskaya, Snezana Zivkovic, Evdoxia Bouka, Prodromos Kanavidis, Helen Dana, Emmanuel Hatzipantelis, Maria Kourti, Maria Moschovi, Sophia Polychronopoulou, Eftichia Stiakaki, Μaria Kantzanou, Apostolos Pourtsidis, Eleni Th Petridou
PURPOSE: To describe epidemiologic patterns of childhood (0-14 years) lymphomas in the Southern and Eastern European (SEE) region in comparison with the Surveillance, Epidemiology and End Results (SEER), USA, and explore tentative discrepancies. METHODS: Childhood lymphomas were retrieved from 14 SEE registries (n = 4,702) and SEER (n = 4,416), diagnosed during 1990-2014; incidence rates were estimated and time trends were evaluated. RESULTS: Overall age-adjusted incidence rate was higher in SEE (16...
October 18, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27757776/erratum-to-association-of-sugary-beverages-with-survival-among-patients-with-cancers-of-the-upper-aerodigestive-tract
#15
Fayth L Miles, Shen-Chih Chang, Hal Morgenstern, Donald Tashkin, Jian-Yu Rao, Wendy Cozen, Thomas Mack, Qing-Yi Lu, Zuo-Feng Zhang
No abstract text is available yet for this article.
October 18, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27752850/single-and-multiple-high-risk-and-low-risk-human-papillomavirus-association-with-cervical-lesions-of-11-224-women-in-jakarta
#16
Lydia S Murdiyarso, Melissa Kartawinata, Iffat Jenie, Grace Widjajahakim, Heriawaty Hidajat, Ruth Sembiring, I Made Nasar, Santoso Cornain, Farid Sastranagara, Ahmad Rusdan Handoyo Utomo
PURPOSE: We sought to evaluate prevalence, age-adjusted distribution, and impact of single and multiple high- and low-risk human papillomavirus (HPV) subtypes and their associations with cervical lesions. METHODS: Data were extracted from 11,224 women who underwent routine screening of HPV genotyping and liquid-based cytology co-testing. Fifteen high-risk (HR) and six low-risk (LR) HPV types were genotyped. RESULTS: Overall HPV prevalence was 10...
October 17, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27734240/sleep-disruption-chronotype-shift-work-and-prostate-cancer-risk-and-mortality-a-30-year-prospective-cohort-study-of-finnish-twins
#17
Barbra A Dickerman, Sarah C Markt, Markku Koskenvuo, Christer Hublin, Eero Pukkala, Lorelei A Mucci, Jaakko Kaprio
PURPOSE: Sleep disruption and shift work have been associated with cancer risk, but epidemiologic evidence for prostate cancer remains limited. We aimed to prospectively investigate the association between midlife sleep- and circadian-related parameters and later prostate cancer risk and mortality in a population-based cohort of Finnish twins. METHODS: Data were drawn from the Older Finnish Twin Cohort and included 11,370 twins followed from 1981 to 2012. Over the study period, 602 incident cases of prostate cancer and 110 deaths from prostate cancer occurred...
November 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27730319/body-mass-index-physical-activity-and-television-time-in-relation-to-mortality-risk-among-endometrial-cancer-survivors-in-the-nih-aarp-diet-and-health-study-cohort
#18
Hannah Arem, Ruth M Pfeiffer, Steven C Moore, Louise A Brinton, Charles E Matthews
PURPOSE: Endometrial cancer (EC) survivors are the second largest group of female cancer survivors in the USA, with high prevalence of obesity and physical inactivity. While higher pre-diagnosis body mass index (BMI) has been associated with higher all-cause and disease-specific mortality, pre-diagnosis physical activity has shown mixed evidence of an association with mortality. However, the association between BMI, physical activity, and TV viewing measured after diagnosis and mortality risk among EC survivors is unknown...
October 11, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27680018/endocrine-therapy-and-urogenital-outcomes-among-women-with-a-breast-cancer-diagnosis
#19
Suzanne N Landi, Kemi M Doll, Jeannette T Bensen, Laura Hendrix, Carey K Anders, Jennifer M Wu, Hazel B Nichols
PURPOSE: Endocrine therapy for breast cancer can exacerbate menopausal symptoms. The association between endocrine therapy and common pelvic floor disorders including urinary incontinence has rarely been evaluated. We examined urogenital and sexual side effects among women with a breast cancer diagnosis, comparing endocrine therapy users to nonusers. METHODS: Urogenital and sexual symptoms were self-reported during the enrollment interview within the University of North Carolina Cancer Survivorship Cohort...
September 28, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27680017/should-low-income-countries-invest-in-breast-cancer-screening
#20
Bishal Gyawali, Tomoya Shimokata, Kazunori Honda, Hiroaki Tsukuura, Yuichi Ando
With the increase in incidence and mortality of breast cancer in low-income countries (LICs), the question of whether LICs should promote breast cancer screening for early detection has gained tremendous importance. Because LICs have limited financial resources, the value of screening must be carefully considered before integrating screening programs into national healthcare system. Mammography-the most commonly used screening tool in developed countries-reduces breast cancer-specific mortality among women of age group 50-69, but the evidence is not so clear for younger women...
September 28, 2016: Cancer Causes & Control: CCC
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