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P & T: a Peer-reviewed Journal for Formulary Management

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https://www.readbyqxmd.com/read/28381922/research-briefs
#1
(no author information available yet)
No abstract text is available yet for this article.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381921/clinical-interventional-oncology-symposium-and-integrative-healthcare-symposium
#2
Walter Alexander
We focus on liver-directed cancer therapy and the role of yittrium-90, as well as one clinician's controversial position against routine use of opioids for chronic pain.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381920/promising-drugs-in-clinical-development-to-treat-advanced-colorectal-cancer
#3
Chris Fellner
We present immunotherapies, biosimilars, and molecular-targeted agents in late-stage development for patients with advanced colorectal cancer.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381919/can-a-short-video-improve-apixaban-knowledge-in-an-inpatient-setting
#4
Christopher Giuliano, Thomas Nofar, Stephanie B Edwin
PURPOSE: To increase patient knowledge about apixaban (Eliquis, Bristol-Myers Squibb) using an educational video delivered in an urban inpatient setting. METHODS: This prospective, quasi-experimental study evaluated knowledge gain and retention in patients receiving apixaban after viewing a short educational video. Knowledge was assessed with a questionnaire immediately before, immediately after, and one month following the educational video. RESULTS: After 33 patients watched the video, scores increased by 19...
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381918/evaluation-of-hydrocortisone-continuous-infusion-versus-intermittent-boluses-in-resolution-of-septic-shock
#5
Hoan Hoang, Shan Wang, Shahidul Islam, Adel Hanna, Alexander Axelrad, Collin Brathwaite
PURPOSE: To compare the effectiveness of continuous infusion of hydrocortisone versus intermittent boluses in the resolution of septic shock. METHODS: A retrospective chart review was performed to investigate the effects of low-dose hydrocortisone continuous infusion (200 mg per day) versus intermittent boluses (50 mg every six hours) in septic shock patients who did not respond to fluid resuscitation and vasopressors. The primary outcome was time to resolution of shock, defined by time from the initiation of hydrocortisone to time of vasopressor withdrawal when mean arterial pressure was greater than 65 mm Hg...
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381917/dosing-of-enoxaparin-in-renal-impairment
#6
Suhail A Shaikh, Randolph E Regal
OBJECTIVE: To review enoxaparin treatment dosing, pharmacokinetics, and clinical outcomes data in patients with renal impairment and to examine the current two-tiered dosing regimen approved by the Food and Drug Administration (FDA). DATA SOURCES: A literature search of PubMed (1990-2016) was performed using the search terms low-molecular-weight heparin, unfractionated heparin, bleeding, enoxaparin, renal impairment, pharmacokinetics, and hemodialysis. STUDY SELECTION AND DATA EXTRACTION: All studies assessing the pharmacokinetic properties of enoxaparin in patients with renal impairment were evaluated...
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381916/republicans-resolve-to-address-high-drug-prices-rhetoric-meets-reality-with-ppaca-replacement
#7
Stephen Barlas
As legislation is drafted to replace Obamacare, pharmaceutical issues-including controlling drug prices, expanding or contracting drug access, and incentivizing the development of generic drugs-are expected to be at the forefront of debate.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381915/flibanserin-addyi-the-first-fda-approved-treatment-for-female-sexual-interest-arousal-disorder-in-premenopausal-women
#8
Clayton English, Anne Muhleisen, Jose A Rey
Flibanserin (Addyi) for female sexual interest/arousal disorder in premenopausal women.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381914/pharmaceutical-approval-update
#9
Mary Choy
Abuse-deterrent hydrocodone bitartrate (Vantrela ER) for long-term opioid treatment; etelcalcetide (Parsabiv) for secondary hyperparathyroidism in patients with chronic kidney disease on hemodialysis; and deflazacort (Emflaza) for Duchenne muscular dystrophy.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381913/drug-and-device-news
#10
(no author information available yet)
Approvals, new indications, regulatory activities, and more.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381912/fda-pleases-no-one-with-final-guidance-on-naming-of-biologicals-and-biosimilars
#11
Stephen Barlas
FDA pleases no one with final guidance on biological and biosimilar naming.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28381911/the-dirty-dozen-twelve-persistent-safety-gaffes-that-we-need-to-resolve
#12
Matthew Grissinger
Twelve persistent safety gaffes that need resolution.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250705/research-briefs
#13
(no author information available yet)
No abstract text is available yet for this article.
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250704/american-college-of-rheumatology-association-of-rheumatology-health-professionals-annual-meeting
#14
Peter Sonnenreich, John Jesitus
We present sessions on establishing key clinical trial outcomes in psoriatic arthritis and on delaying the radiographic progression of ankylosing spondylitis.
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250703/targeting-interleukin-5-in-patients-with-severe-eosinophilic-asthma-a-clinical-review
#15
Christine Lam, Kunal J Shah, Rupal Mansukhani
Interleukin-5 (IL-5) is known to play a major role in the growth, differentiation, recruitment, and activation of eosinophils. The authors review the efficacy and safety of two IL-5-targeting agents used in the treatment of eosinophilic asthma.
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250702/an-evaluation-of-selected-indications-and-appropriateness-of-ampicillin-sulbactam-an-unrestricted-antimicrobial-at-a-single-center
#16
Dorothy McCoy, Rani Sebti, Arpi G Kuyumjian
BACKGROUND: With antimicrobial resistance on the rise and few new agents in development, it is important to exercise prudent judgment when utilizing antimicrobials. The Antimicrobial Stewardship Program (ASP) is responsible for facilitating the appropriate use of antimicrobials at the institution. Restricted antimicrobials and select additional antimicrobials are monitored by the ASP team to determine if the indications chosen by the ordering prescribers correspond to and are appropriate for the patients' infections...
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250701/medicinal-cannabis-history-pharmacology-and-implications-for-the-acute-care-setting
#17
Mary Barna Bridgeman, Daniel T Abazia
The authors review the historical use of medicinal cannabis and discuss the agent's pharmacology and pharmacokinetics, select evidence on medicinal uses, and the implications of evolving regulations on the acute care hospital setting.
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250700/fda-revisits-rules-on-drug-and-device-communication-will-the-agency-relax-existing-industry-opposed-restrictions
#18
Stephen Barlas
The Food and Drug Administration issued draft guidances in January that tackled health care economic information and product labeling. Do these publications indicate a potential shift in on- and off-label policies for drugs and devices?
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250699/rolapitant-varubi-a-substance-p-neurokinin-1-receptor-antagonist-for-the-prevention-of-chemotherapy-induced-nausea-and-vomiting
#19
Tamara Goldberg, Brooke Fidler, Stephanie Cardinale
Rolapitant (Varubi) for the prevention of chemotherapy-induced nausea and vomiting.
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28250698/pharmaceutical-approval-update
#20
Mary Choy
Insulin degludec/liraglutide (Xultophy 100/3.6) for type-2 diabetes; rucaparib (Rubraca) for the treatment of deleterious BRCA mutation-associated ovarian cancer; and nusinersen (Spinraza) for the treatment of spinal muscular atrophy.
March 2017: P & T: a Peer-reviewed Journal for Formulary Management
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