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P & T: a Peer-reviewed Journal for Formulary Management

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https://www.readbyqxmd.com/read/29622946/research-briefs
#1
(no author information available yet)
No abstract text is available yet for this article.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622945/genitourinary-cancers-symposium-and-integrative-healthcare-symposium-annual-conference
#2
Walter Alexander
We present coverage of advances in renal cell carcinoma and prostate cancer, as well as sessions on addiction relapse prevention and the role of integrative care.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622944/intense-focus-yet-many-setbacks-for-alzheimer-s-disease-drug-development
#3
Troy Kish
Despite failures in late-phase trials, the pipeline of medications for Alzheimer's disease is robust as companies hope to be the first to bring an effective therapy to market. We review several investigational agents in late-stage development.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622943/management-and-preventive-measures-for-febrile-neutropenia
#4
Austin J Lucas, Jacqueline L Olin, Megan D Coleman
Febrile neutropenia (FN) is an oncological emergency and serious complication often resulting from chemotherapy. In patients with a weak or completely suppressed immune system, a fever may be the only sign of an underlying infection and immediate treatment is needed. Using risk evaluation scores, it is possible to stratify individual patient degree of risk. However, all patients warrant immediate antibiotic coverage. Antibiotic treatment of FN is broadened or narrowed based on individualized clinical scenarios...
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622942/pharmacological-agents-utilized-in-patients-with-type-2-diabetes-beyond-lowering-a1c
#5
Joanna W Chung, Melody L Hartzler, Ashley Smith, Jessica Hatton, Kristi Kelley
Staying up to date with evolving pharmacotherapies is important to providing optimal therapies to patients. The authors present available evidence to support the role of novel and existing agents in treating type-2 diabetes.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622941/frustration-over-generic-drug-shortages-and-prices-prompts-federal-and-private-actions-health-systems-take-matters-into-their-own-hands
#6
Stephen Barlas
Generic shortages are draining hospital resources throughout the U.S. and in some cases imperiling inpatient treatment. The author considers the FDA's performance and describes the approach some health systems are taking to create a solution.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622940/plecanatide-trulance-for-chronic-idiopathic-constipation-and-irritable-bowel-syndrome-with-constipation
#7
Julia A Kamuda, Nissa Mazzola
Plecanatide (Trulance) for chronic idiopathic constipation and irritable bowel syndrome with constipation.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622939/pharmaceutical-approval-update
#8
Mary Choy
Netarsudil ophthalmic solution (Rhopressa) for the reduction of elevated intraocular pressure; ertugliflozin (Steglatro) for adults with type-2 diabetes; and lutetium lu 177 dotatate (Lutathera) for certain gastroenteropancreatic neuroendocrine tumors.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622938/drug-and-device-news
#9
(no author information available yet)
Approvals, new indications, regulatory activities, and more.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622937/cms-consideration-of-rebate-overhaul-elicits-strong-opinions-both-pro-and-con
#10
Stephen Barlas
CMS consideration of rebate overhaul elicits strong opinions.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29622936/severe-harm-and-death-associated-with-errors-and-drug-interactions-involving-low-dose-methotrexate
#11
Matthew Grissinger
Harm and death associated with methotrexate errors.
April 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29493661/right-to-try-legislation-should-focus-on-patients-not-politics
#12
COMMENT
Richard Klein
No abstract text is available yet for this article.
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491702/research-briefs
#13
(no author information available yet)
No abstract text is available yet for this article.
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491701/asco-gastrointestinal-cancers-symposium-and-san-antonio-breast-cancer-symposium
#14
Walter Alexander
We present sessions on hepatocellular carcinoma and colorectal and pancreatic cancers from ASCO GI. Key sessions from SABCS covered dose intensification, new trial data, and ovarian suppression to preserve fertility.
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491700/price-performance-ratio-analysis-of-enteral-vitamin-k-formulations
#15
Patrick Rose, Gregory Cwikla, Christopher Miller, Luke Probst, Robert Seabury
Background: Vitamin K compounded oral solution costs significantly less on a per-milligram basis compared with tablet formulations. Current literature has shown that international normalized ratio (INR) lowering in the reversal of vitamin K antagonists (VKAs) occurs to a similar degree when using vitamin K oral solution compared with tablet formulations. Objective: To compare drug spending on vitamin K oral solution versus tablet using a price-performance ratio (PPR)...
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491699/expediting-formulary-standardization-in-a-multihospital-health-system-using-layered-learners
#16
Amanda J Hays, Jennifer R Smith, Rebecca M Guth, Susan E Samet
Drug formularies are a necessary part of medication management in hospitals and health systems. The system-level P&T committee at BJC HealthCare, a multihospital health system in St. Louis, Missouri, developed an approach to standardization of a system-wide formulary using available layered learners to complete the work in an expedited manner before implementation of a system-wide electronic medical record. The formulary standardization work was allocated to reviewers-including pharmacy students, residents, clinical pharmacy specialists, and pharmacy leadership-according to the complexity of the drug class under review, and a pharmacist was assigned to oversee and support the learner (student or resident) as class reviews were performed...
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491698/current-practice-patterns-in-the-management-of-alcohol-withdrawal-syndrome
#17
Yoonsun Mo, Michael C Thomas, Corey S Laskey, Natalia Shcherbakova, Megan L Bankert, Robert H Halloran
Objective: The aim of this study was to examine current practice patterns surrounding the management of alcohol withdrawal syndrome (AWS) in the Northeast region of the United States. Methods: A survey questionnaire with several treatment options related to current practice in the management of AWS was developed. All hospitals with 100 beds or more located in the Northeast region were selected, and 512 surveys were mailed to pharmacy directors of those hospitals...
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491697/time-and-temperature-controlled-transport-supply-chain-challenges-and-solutions
#18
Claire Sykes
The author reviews the latest improvements and advancements in the pharmaceutical supply chain, including those in packaging, monitoring, warehousing, and regulation.
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491696/the-21st-century-cures-act-fda-implementation-one-year-later-some-action-some-results-some-questions
#19
Stephen Barlas
The Food and Drug Administration has made significant progress implementing some of the 60 provisions of the 21st Century Cures Act passed in 2016. The author discusses the successes and shortcomings of the agency's regulatory activities.
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29491695/oritavancin-orbactiv-a-new-generation-lipoglycopeptide-for-the-treatment-of-acute-bacterial-skin-and-skin-structure-infections
#20
Samantha Rosenthal, Arnold G Decano, Aiman Bandali, Denise Lai, Gregory E Malat, Tiffany E Bias
Oritavancin (Orbactiv): a new-generation lipoglycopeptide for the treatment of acute bacterial skin and skin structure infections.
March 2018: P & T: a Peer-reviewed Journal for Formulary Management
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