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Photodermatology, Photoimmunology & Photomedicine

M C Kirchberger, M V Heppt, T K Eigentler, M A Kirchberger, G Schuler, L Heinzerling
BACKGROUND: The incidence of melanoma has been rising worldwide. One possible reason for this is natural and artificial UV exposure. Only little data on actual consumer statistics from tanning studios and the usage of sunscreen are available. Therefore, it is difficult to describe trends for both and identify the impact of preventive measures. METHODS: To gain knowledge about the popularity of "tanning bed" and "sunscreen", normalized search volumes for both search queries were obtained from Google Trends for 11 countries between January 2004 and June 2016...
December 31, 2016: Photodermatology, Photoimmunology & Photomedicine
Keiichi Hiramoto, Satoshi Yokoyama, Yurika Yamate
BACKGROUND: We previously reported that ultraviolet (UV) A eye irradiation reduces the ulcerative colitis induced by dextran sodium sulfate (DSS). This study examined the effects of UVA on colon carcinoma induced by azoxymethane (AOM) and DSS. METHODS: We irradiated the eyes of ICR mice with UVA at a dose of 110 kJ/m(2) using an FL20SBLB-A lamp for the experimental period. RESULTS: In mice treated with these drugs, the symptom of colon carcinoma were reduced by UVA eye irradiation...
December 31, 2016: Photodermatology, Photoimmunology & Photomedicine
Steven Q Wang, Haoming Xu, Stephen W Dusza, Judy Hu, Joseph Stanfield
Sunscreens are effective in preventing sunburn, skin cancers and signs of photoaging [1]. Over the past decades, a sustained effort to educate the public on the benefit of sunscreen use and proper application techniques has been carried out by dermatologists, academia, industry and non-profit organizations [2]. Although the public understands the benefits of sunscreen use [3, 4], the vast majority do not use sunscreen on a routine basis due to a variety of reasons [5]. The aim of this study was to investigate whether sunscreen compliance can be improved by changing accessibility and storage location...
December 31, 2016: Photodermatology, Photoimmunology & Photomedicine
Kelsie Riemenschneider, Jennifer G Powers
Minocycline is a tetracycline antibiotic that can induce hyperpigmentation and scarring of the skin, nails, mucous membranes, thyroid, teeth, bones, and heart valves. Minocycline-induced cutaneous hyperpigmentation consists of three types. Type I pigmentation occurs in areas of prior inflammation such as scars, and it is not thought to be dependent on treatment dose or duration. Type II and type III pigmentation, which occur on normal skin and sun-exposed skin, respectively, appear to be dose-related. This side effect can persist for years if not permanently despite treatment attempts, and definitive therapy does not exist...
December 31, 2016: Photodermatology, Photoimmunology & Photomedicine
Eriko Misawa, Miyuki Tanaka, Marie Saito, Kazumi Nabeshima, Ruiqing Yao, Kouji Yamauchi, Fumiaki Abe, Yuki Yamamoto, Fukumi Furukawa
BACKGROUND: Aloe vera is a traditional medical plant whose gel has been widely used in skin care. Previously, we have identified Aloe sterols from Aloe vera as active ingredients. The present study investigated the protective effects of Aloe sterols without polysaccharides, against ultraviolet B (UVB)-induced skin photoaging in mice using Aloe vera gel extract (AVGE) obtained by supercritical fluid extraction. METHODS: AVGE was supplemented in the diet (12 or 120 ppm) and HR-1 hairless mice were exposed to UVB irradiation for 7 weeks...
December 20, 2016: Photodermatology, Photoimmunology & Photomedicine
Kimberly A Miller, Jimi Huh, Jennifer B Unger, Jean L Richardson, Martin W Allen, David H Peng, Myles G Cockburn
BACKGROUND/PURPOSE: Rates of melanoma are rising in Hispanics in the United States. Excessive sun exposure in childhood increases the risk of melanoma in adulthood, and little is known about the factors motivating sun protection behaviors among Hispanic youth. METHODS: Correlates of sun protection were examined among Hispanic children residing in Los Angeles, California (N=1,891). Associations between multiple constructs (psychosocial, familial and cultural) and sun protection outcomes (use of sunscreen, protective clothing, and shade seeking/sun avoidance) were examined...
December 20, 2016: Photodermatology, Photoimmunology & Photomedicine
Jia Zhang, Ruhong Cheng, Xia Yu, Zhonghui Sun, Ming Li, Zhirong Yao
BACKGROUND: Xeroderma pigmentosum (XP) is a rare genodermatoses characterized by exaggerated sunburn reactions, freckle-like pigmentation and a high possibility of developing cutaneous tumors. XP comprised seven complementation groups (from XP-A to XP-G) and a variant form XP-V. METHODS: This study was based on five unrelated Chinese families with six patients clinically suspected to be XP. Mutation screening was performed by direct sequencing of the entire coding region of eight XP genes...
December 16, 2016: Photodermatology, Photoimmunology & Photomedicine
Ruifeng Sun, Hui Chen, Wei Zhu, Shi Lian
Porokeratosis (PK), initially described by Mibelli in 1893, is a skin disorder of epidermal keratinization. This disorder is clinically characterized by annular plaques with edges and atrophic centers, as well as histopathologically characterized by the presence of cornoid lamella. The etiology of this disease remains unknown. Several genes have been reported as causative genes, such as mevalonate kinase, phosphomevalonate kinase, mevalonate decarboxylase, and farnesyl diphosphate synthase. The four genes participate in the mevalonate pathway, which may be involved in the proliferation and differentiation of keratinocytes (1, 2)...
December 16, 2016: Photodermatology, Photoimmunology & Photomedicine
Anju Yadav, Asheesh Gupta
The innumerable intricacies associated with chronic wounds have made the development of new painless, non-invasive, biophysical therapeutic interventions as the focus of current biomedical research. Red and near-infrared light-induced photobiomodulation therapy appears to emerge as a promising drug-free approach for promoting wound healing, reduction of inflammation, pain and restoration of function owing to penetration power in conjunction with their ability to positively modulate the biochemical and molecular responses...
December 10, 2016: Photodermatology, Photoimmunology & Photomedicine
Maximilian Andreas Storz, Benjamin Gronwald, Sven Gottschling, Jakob Schöpe, Russalina Mavrova, Sascha Baum
BACKGROUND: The aim of our study was to examine the effects of Photobiomodulation Therapy (PBMT) in the treatment of breast cancer-related lymphedema using a compactly designed treatment regime consisting of eight therapy sessions in combination with a cluster laser device covering a total area size of 78.54 cm² over the axillary. METHODS: 40 patients with unilateral lymphedema were enrolled in this double blind, placebo-controlled trial in order to evaluate effects of PBMT on lymphedema-related pain, quality of life, grip strength and limb volume difference...
December 10, 2016: Photodermatology, Photoimmunology & Photomedicine
Y N Chaves, L A Torezan, S Lourenço, C F Neto
INTRODUCTION: Actinic cheilitis (AC) is a lip intraepithelial neoplasia, whose cells present alterations similar to those presented by invasive squamous cell carcinomas (SCC). OBJECTIVE: To conduct clinical and laboratory evaluation by histopathology and immunohistochemistry of the efficacy of actinic cheilitis treatment using photodynamic therapy (PDT) with methyl aminolevulinate (MAL) and non-coherent red light. MATERIALS AND METHODS: Patients with actinic cheilitis detected by histopathological examination were submitted to two sessions of photodynamic therapy with a two-week interval between them...
November 19, 2016: Photodermatology, Photoimmunology & Photomedicine
L F Kuklinski, M S Zens, A E Perry, A C Green, M R Karagas
BACKGROUND: Skin microtopography as a measure of photoaging is a non-invasive approach to measuring chronic ultraviolet radiation (UVR) exposure, and reflects the degree of dermal elastosis in populations of European descent in the subtropics. Less is known about the utility of this approach in populations at different latitudes, and whether it relates to skin cancer risk. METHODS: A population-based case-control study of 342 SCC cases and 331 age- and gender-matched controls were evaluated for histologic evidence of solar damage and severity of photoaging based on microtopography on a six-grade scale...
November 19, 2016: Photodermatology, Photoimmunology & Photomedicine
Ronghua Li, Meng Qiao, Xiaoyan Wang, Xintong Zhao, Qing Sun
BACKGROUND: The treatment of vitiligo is still one of the most difficult dermatological challenges, although there are many therapeutic options. Narrow band ultraviolet B (NB-UVB) phototherapy is considered to be a very important modality for generalized vitiligo. OBJECTIVE: The aim of this study was to explore whether a combination of NB-UVB and topical agents would be superior to NB-UVB alone for treating vitiligo. METHODS: We searched the electronic databases such as PUBMED, EMBASE, Cochrane Library and Web of Science...
October 1, 2016: Photodermatology, Photoimmunology & Photomedicine
Chang Taek Oh, Tae-Rin Kwon, Eun Ja Choi, Soon Re Kim, Joon Seok, Seog Kyun Mun, Kwang Ho Yoo, Yeon Shik Choi, Sun Young Choi, Beom Joon Kim
BACKGROUND: Skin hyperpigmentary disorders including postinflammatory hyperpigmentation, melasma, solar lentigines, and conditions like freckles are common. The light-emitting diodes (LEDs) are the latest category of nonthermal and noninvasive phototherapy to be considered in skin pigmentation disorder treatment. PURPOSE: The purpose of this study was to investigate the effects of 660-nm LED on inhibition of melanogenesis. We investigated whether a 660-nm LED affected melanin synthesis in in vitro and in vivo models, and we explored the mechanisms involved...
October 1, 2016: Photodermatology, Photoimmunology & Photomedicine
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Photodermatology, Photoimmunology & Photomedicine
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Photodermatology, Photoimmunology & Photomedicine
(no author information available yet)
The above article, published online on November 6, 2015 in Wiley Online Library (, has been retracted by agreement between the authors, the journal Editor in Chief, Thomas M. Ruenger, MD PhD and John Wiley & Sons Ltd. The retraction has been agreed as the clinical trial reported in this manuscript was not approved by the local Ethics Committee. Reference Calzavara-Pinton PG, Rossi MT, Zanca A, Arisi M, Gonzalez S, Venturini M. Oral Polypodium leucomotos increases the anti-inflammatory and melanogenic responses of the skin to different modalities of sun exposures: a pilot study...
September 2016: Photodermatology, Photoimmunology & Photomedicine
Juan Pablo Castanedo-Cázares, Juan Diego Cortés-García, Cornelia Fuentes-Ahumada, Karla Martinez-Rosales, Bertha Torres-Álvarez
BACKGROUND/PURPOSE: Vitiligo is the most commonly acquired depigmentation disorder of the skin and is characterized by the destruction of melanocytes. Ultraviolet phototherapy with narrow band (UVB-NB) induces proliferation, differentiation, maturation, and migration of melanocytes. The clinical repigmentation is featured by follicular, marginal, and diffuse patterns. The aim of this study was to observe the process involved in the melanocyte migration and proliferation among these patterns and the unresponsive lesions following UVB-NB phototherapy...
September 2016: Photodermatology, Photoimmunology & Photomedicine
Beata Mianowska, Joanna Narbutt, Antony Richard Young, Wojciech Fendler, Beata Małachowska, Wojciech Młynarski, Aleksandra Lesiak
BACKGROUND: Seasonal variation in glycated hemoglobin levels has been observed, and sun exposure has been considered as one of the factors associated with this relationship. Fructosamine is a short-time marker of blood protein glycation. AIM: We investigated the effect of seven days of sunbathing on blood fructosamine concentration in healthy volunteers using different ultraviolet radiation (UVR) protections. MATERIALS AND METHODS: Participants were assigned to one of three groups: group A - used a UVA and UVB absorbing sunscreen (N = 15), group B - used a UVB absorbing sunscreen (N = 18), and group C - followed uncontrolled sun protection habits (N = 22)...
September 2016: Photodermatology, Photoimmunology & Photomedicine
Juliette M Hardy, Marie-Claude Marguery, Anne Huynh, Cécile Borel, Pol André Apoil, Laurence Lamant, Emilie Tournier, Chloé Alberto, Céline Pauwels, Marianne Thomas, Juliette Mazereeuw Hautier, Carle Paul, Cristina Bulai Livideanu
Overlap chronic graft-versus-host disease (GVHD) associates both features of acute and chronic GVHD. Trigger factors for chronic GVHD are unclear. We describe two patients who received allogenic haematopoietic stem-cell transplantation, and who later developed overlap chronic GVHD after sun exposure. Available data from in vivo investigations suggest ultraviolet B radiation (UVB) has a beneficial effect on acute and chronic GVHD. The role of sun irradiation as a trigger for isomorphic cutaneous GVHD has been rarely reported in the literature...
September 2016: Photodermatology, Photoimmunology & Photomedicine
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