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Photodermatology, Photoimmunology & Photomedicine

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https://www.readbyqxmd.com/read/28793178/ultraviolet-and-infrared-induced-11-beta-hydroxysteroid-dehydrogenase-type-1-activating-skin-photoaging-is-inhibited-by-red-ginseng-extract-containing-high-concentrations-of-ginsenoside-rg3-s
#1
Jin-Ju Nam, Ji-Eun Min, Min-Ho Son, Jin-Hwan Oh, Seunghyun Kang
BACKGROUND: Sun irradiation is one of major extrinsic stressors responsible for premature skin aging through activation and expression of 11 beta hydroxysteroid dehydrogenase type 1 (11β-HSD1), which converts inactive cortisone to active cortisol. The aim of this study was to evaluate the inhibitory effects of red ginseng extract containing high concentrations of ginsenoside Rg3(S) (GERg3) on 11β-HSD1-induced skin photoaging. METHODS: To evaluate the inhibitory effects of GERg3 on ultraviolet (UV) or infrared (IR)-induced skin photoaging, human dermal fibroblasts or a normal human 3D skin model were exposed to UV or an IR...
August 9, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28793173/mania-induced-by-narrowband-ultraviolet-b-phototherapy-treatment-a-case-report-and-review-of-the-literature
#2
LETTER
Rachel Elizabeth Ward, Eva Waineo, Jessica Ann Kado
Phototherapy has been used for decades in the treatment of many common dermatologic conditions, such as psoriasis, atopic dermatitis, cutaneous T cell lymphoma, vitiligo, and scleroderma, among others. Prior to the commencement of phototherapy, many factors must be considered. For dermatologists, the most important factors include the determination of a patient's skin phototype, concurrent use of photosensitizing agents, and calculation of minimal erythema dose (MED). Though infrequent, the side effects to phototherapy commonly discussed with patients include burns, ocular toxicity, polymorphous light eruption, potential for skin carcinogenesis, and possible worsening of the skin disease...
August 9, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28767162/protective-molecular-mechanisms-of-resveratrol-in-uvr-induced-skin-carcinogenesis
#3
REVIEW
Saba W Aziz, Moammir H Aziz
Skin cancer is a major health problem worldwide. It is the most common cancer in the United States and poses a significant healthcare burden. Excessive UVR exposure is the most common cause of skin cancer. Despite various precautionary measures to avoid direct UVR exposure, the incidence of skin cancer and mortality related to it remains high. Furthermore, the current treatment options are expensive and have side effects including toxicity to normal cells. Thus, a safe and effective approach is needed to prevent and treat skin cancer...
August 2, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28767160/sunscreen-creams-containing-naringenin-nanoparticles-formulation-development-and-in-vitro-and-in-vivo-evaluations
#4
Haritima Joshi, Aswathi R Hegde, Pallavi K Shetty, Hemanth Gollavilli, Renuka S Managuli, Guruprasad Kalthur, Srinivas Mutalik
BACKGROUND: The aim of this study was to develop sunscreen creams containing polymeric nanoparticles (NPs) of naringenin for photo-protective and antioxidant effects. METHODS: Polymeric NPs of naringenin were prepared and optimized. The NPs were incorporated into sunscreen creams and evaluated for in vitro and in vivo skin retention. RESULTS: The optimized naringenin NPs showed a size of 131.2 nm, zeta potential -25.4 mV and entrapment efficiency 32...
August 2, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28766918/the-skin-microbiome-and-immune-system-potential-target-for-chemoprevention
#5
REVIEW
Mohammad Asif Sherwani, Saba Tufail, Anum Fatima Muzaffar, Nabiha Yusuf
There has been increasing interest in understanding the role of the human microbiome in skin diseases. Microbiome studies are being utilized in skin cancer research in numerous ways. Commensal bacteria are being studied as a potential tool to judge the biggest environmental risk of skin cancer, ultraviolet (UV) radiation. Owing to the recognized link of skin microbes in the process of inflammation, there have been theories linking commensal bacteria to skin cancer. Viral metagenomics has also provided insight into virus linked forms of skin cancers...
August 2, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28703505/tanners-awareness-and-perceptions-of-legislation-for-tanning-bed-use
#6
LETTER
Vinayak K Nahar, Effie Olendzki, Joel J Hillhouse, Sherry L Pagoto
No abstract text is available yet for this article.
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28703377/protective-effect-of-moisturizers-on-photoaging
#7
LETTER
Sung Jay Choe, Seung Phil Hong, Jiyeon Yoo, Bo-Kyung Kim, Se Kyoo Jeong, Hana Bak, Sung Ku Ahn
No abstract text is available yet for this article.
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28703365/phototherapy-in-systemic-sclerosis-review
#8
REVIEW
Suteeraporn Chaowattanapanit, Charoen Choonhakarn, Chingching Foocharoen, Narachai Julanon
Systemic scleroderma-also known as systemic sclerosis (SSc)-is a chronic systemic connective tissue disease characterized by collagen deposition in cutaneous and internal organs, leading to skin sclerosis and multiple organ fibrosis. The pathogenesis is complex and remains poorly understood. Treatment is based on organ involvement and requires a multidisciplinary approach. Skin sclerosis can cause disability, leading to decreasing quality of life. Various systemic antifibrotic therapies have been used; however, most have unsatisfactory results...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28703320/5-aminolevulinic-acid-patch-pdt-in-the-treatment-of-actinic-cheilitis
#9
Sonja Radakovic, Adrian Tanew
BACKGROUND: Actinic cheilitis (AC) is a common disease caused by chronic ultraviolet exposure. OBJECTIVE: Alacare is a self-adhesive, skin coloured 5-aminolaevulinic acid (ALA) patch that has been developed for the treatment of mild to moderate actinic keratosis (AK). Considering the good results in the treatment of AK, the standardized delivery of ALA and the simple application Alacare patch PDT appears as an interesting treatment option for AC. METHODS: We retrospectively assessed the efficacy, tolerability and cosmetic outcome of Alacare patch PDT in eleven patients with AC...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28703311/mechanisms-and-prevention-of-uv-induced-melanoma
#10
REVIEW
Ashley Sample, Yu-Ying He
Melanoma is the deadliest form of skin cancer and its incidence is rising, creating a costly and significant clinical problem. Exposure to ultraviolet (UV) radiation, namely UVA (315-400 nm) and UVB (280-315 nm), is a major risk factor for melanoma development. Cumulative UV radiation exposure from sunlight or tanning beds contributes to UV-induced DNA damage, oxidative stress, and inflammation in the skin. A number of factors, including hair color, skin type, genetic background, location, and history of tanning, determine the skin's response to UV radiation...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28681504/melanoma-and-non-melanoma-skin-cancer-chemoprevention-a-role-for-nicotinamide
#11
REVIEW
Rashi Minocha, Diona L Damian, Gary M Halliday
Ultraviolet radiation (UVR) causes DNA damage in melanocytes by producing photolesions such as cyclobutane pyrimidine dimers and 8-oxo-7-hydrodeoxyguanosine. The production of reactive oxygen species by UVR also induces inflammatory cytokines that, together with the inherent immunosuppressive properties of UVR, propagate carcinogenesis. Nicotinamide (Vitamin B3 ) enhances DNA repair, modulates the inflammatory environment produced by UVR and reduces UV-induced immunosuppression. As nicotinamide reduces the incidence of actinic keratoses and non-melanoma skin cancers in high-risk individuals, and enhances repair of DNA damage in melanocytes, it is a promising agent for the chemoprevention of melanoma in high-risk populations...
July 5, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28661557/indeterminate-cell-histiocytosis-a-case-treated-with-ultraviolet-b-narrow-band-phototerapy-nb-uvb
#12
LETTER
Alessia Pacifico, Giovanni Leone, Giovanni Damiani, Carmela Ferraro, Paolo Iacovelli, Andrea Paro Vidolin, Luca Muscardin
Neoplasms of histiocytes, as well as of dendritic cells-derived, are rare entities and all of them derived from a common medullar progenitor CD34(+) . Recently, histiocytosis were grouped and re-classified in the following entities: histiocytic sarcoma, tumours derived from Langerhans cells, interdigitating dendritic cell sarcoma and the follicular dendritic cell sarcoma; furthermore, two more rare entities have been described:fibroblastic reticular cell tumour and the indeterminate dendritic cell tumour. This article is protected by copyright...
June 29, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28660721/a-cross-sectional-comparative-study-of-home-vs-in-office-nbuvb-phototherapy-for-vitiligo
#13
LETTER
Jean-Claire P Dillon, ChiAyrsh Ford, Linda S Hynan, Amit G Pandya
Narrowband ultraviolet B (NB-UVB) phototherapy is an effective treatment for vitiligo, resulting in up to 75% repigmentation in 9 months, however, compliance is often poor due to the economic burden and inconvenience associated with this form of therapy. Home phototherapy has been shown to be an effective treatment for a variety of skin conditions, including vitiligo. Despite this evidence, home phototherapy for vitiligo is considered experimental and investigational by health insurance providers. This article is protected by copyright...
June 29, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28620923/home-phototherapy-in-vitiligo
#14
REVIEW
Tasneem F Mohammad, Narumol Silpa-Archa, James L Griffith, Henry W Lim, Iltefat H Hamzavi
Vitiligo is a disorder characterized by the development of depigmented macules and patches. Narrowband ultraviolet B phototherapy is a standard of care treatment and is used both as monotherapy and in combination with other treatment modalities to induce repigmentation. Although phototherapy is safe and effective, its use is limited due to the significant time commitment required and associated costs. Home phototherapy is a safe and effective alternative to make phototherapy more accessible to patients. However, it is often underutilized due to lack of physician experience and comfort as well as misconceptions regarding its safety and efficacy...
June 16, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28602032/comparative-evaluation-of-efficacy-and-safety-of-calcipotriol-versus-tacalcitol-ointment-both-in-combination-with-nbuvb-phototherapy-in-the-treatment-of-stable-plaque-psoriasis
#15
Ishita Dua, Kamal Aggarwal, V K Jain
BACKGROUND: Vitamin D analogues and NBUVB phototherapy are both well-established modalities of treatment in psoriasis. The objective of this open label, intra individual, left right study was to compare two different Vitamin D analogues, calcipotriol and tacalcitol, in combination with NBUVB phototherapy in chronic stable plaque psoriasis. METHODS: Thirty patients with stable plaque psoriasis were enrolled for a 12 week clinical trial. The target lesion on left side was treated topically with tacalcitol ointment once daily, while that on the right side was treated with calcipotriol ointment twice daily...
June 11, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28602025/a-method-to-assess-the-protective-efficacy-of-sunscreens-against-visible-light-induced-pigmentation
#16
Luc Duteil, Jane Esdaile, Yves Maubert, Anne-Claire Cathelineau, Anne Bouloc, Catherine Queille-Roussel, Thierry Passeron
BACKGROUND: Until now, photoprotection of human skin has involved the development of sunscreens effective in the ultraviolet (UV) domain. During the last ten years, several studies have shown that besides the well-known damaging effects of UV, visible (400-700 nm) and even infrared light (> 700 nm) can induce damage which contributes to photoaging. Furthermore, many photodermatoses are also known to be triggered by visible light (VL). OBJECTIVE/METHOD: An in vivo method is proposed to assess the protective efficacy of sunscreens in the VL domain...
June 11, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28580732/polymorphic-light-eruption-with-severe-abnormal-phototesting-sensitivity-plesaps
#17
LETTER
Catriona P Harkins, Alex J Waters, Robert S Dawe, James Ferguson, Sally H Ibbotson
Polymorphic light eruption (PLE) affects 18% of people in Northern Europe. It is characterised by a delayed-onset pruritic photo-exposed site papular eruption after sun exposure.There is considerable heterogeneity in presentation, morphology and severity. This article is protected by copyright. All rights reserved.
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28580718/resolution-of-aquagenic-pruritus-with-intermittent-uva-nbuvb-combined-therapy
#18
LETTER
Daniel Morgado-Carrasco, José Riera-Monroig, Xavier Fustà-Novell, Sebastian Podlipnik, Paula Aguilera
Aquagenic pruritus (AP) is a rare skin disease of unknown aetiology characterized by the abrupt onset of pruritus without visible cutaneous lesions after contact with water or humidity. AP can have a severe impact on the patient's quality of life. Although AP is mostly idiopathic, it can be associated with polycythemia vera, other hematologic disorders and medications (1). Treatment is challenging and often disappointing, and may consist in topical agents such as capsaicin 0.025-1.0%, alkaline baths and glycerol trinitrate 2%...
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28580653/porokeratosis-ptychotropica-responding-to-photodynamic-therapy-an-alternative-treatment-for-a-refractory-disease
#19
X Fustà-Novell, S Podlipnik, A Combalia, D Morgado-Carrasco, J Ferrando, J M Mascaró, P Aguilera
BACKGROUND: Porokeratosis ptychotropica (PP) is a rare variant of porokeratosis with a special predisposition to affect body folds, particularly the intergluteal cleft. This disease is resistant to most topical and systemic treatments reported, as shown in the review of the literature we provide here. Itching and discomfort are often a difficult problem to solve. PATIENTS AND METHODS: Two patients with PP that had not responded to multiple topical treatments were treated with photodynamic therapy (PDT)...
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28695663/editorial
#20
EDITORIAL
Thomas M Rünger, Li-Fang Wang, Cheng-Che E Lan
No abstract text is available yet for this article.
July 2017: Photodermatology, Photoimmunology & Photomedicine
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