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Photodermatology, Photoimmunology & Photomedicine

Jose-Manuel Carrascosa, Nuria Floriach, Elisabet Sala, Jose Aguilera
In recent years, there has been a growing interest in the use of naturally occurring substances with antioxidant and/or photoprotective effects to complement solar filters in strategies designed to minimise the adverse effects of ultraviolet radiation (UVR) because of the potential benefits that could be obtained with such ingredients without interfering with vitamin D synthesis in the skin. This article is protected by copyright. All rights reserved.
May 15, 2017: Photodermatology, Photoimmunology & Photomedicine
Tae In Kim, Hye-Jin Ahn, In Hye Kang, Ki-Heon Jeong, Nack In Kim, Min Kyung Shin
BACKGROUND: Photodynamic therapy (PDT) has been reported as an effective alternative treatment for patients with acne. PURPOSE: To evaluate the efficacy and safety of DL-PDT in moderate to severe acne and to compare outcomes with those of laser-assisted daylight photodynamic therapy. METHODS: Patients were randomly assigned to either a DL-PDT group (D group) or a fractional laser-assisted DL-PDT group (F group). The outcomes were assessed by measuring acne lesion counts and severity grade at 4, 8, 12, and 16 weeks after therapy commenced...
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
Giedre Bieliauskiene, Peter A Philipsen, Hans Christian Wulf
People's UV sensitivity can be predicted by measuring skin pigmentation (1,2). Constitutive pigmentation is often measured on the inner arm (3,4), but the best suited place is on previously sun-unexposed buttocks, where pigmentation is considered to be constant throughout life. However, this anatomical site is not as easily accessible as the inner arm, and it is less convenient to use in large-scale studies. There are indications that pigmentation measurements on buttocks skin and inner arm are not interchangeable (5), and it is unclear if the inner arm can be used for measurement of constitutive pigmentation...
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
T Gracia Cazaña, S González, A Juarranz, Y Gilaberte
Basal cell carcinoma (BCC) is the most common skin cancer, with an incidence rate in Spain of 113.05 cases per 100 000 person-years (CI95%, 89.03-137.08).(1) Pigmented BCCs (pBCCs), is a clinical and histological variant of BCC that exhibits increased pigmentation. pBCCs account for 6.7% to 8.5% of BCCs, and show a racial predilection.(2-3) This article is protected by copyright. All rights reserved.
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
D Rutkowski, M D Farrar, J E Osman, A R Webb, L E Rhodes
BACKGROUND: Solar UVR is a major cause of skin cancer but also an important source of vitamin D (VitD), essential for musculoskeletal health. Conflicting public health messages may confuse skin cancer patients prone to further skin cancer. OBJECTIVE: To explore the knowledge, behaviour and attitudes of skin cancer patients to sunlight exposure and VitD sources. METHODS: Patients (n=10) previously treated for multiple basal cell cancer in a hospital setting, participated in focus group sessions with semi-structured discussions to explore: knowledge of VitD, sun-avoidance behaviour, and attitude towards sunlight exposure messages...
April 27, 2017: Photodermatology, Photoimmunology & Photomedicine
Arif Aslam, Lynn Fullerton, Sally Helen Ibbotson
No abstract text is available yet for this article.
April 17, 2017: Photodermatology, Photoimmunology & Photomedicine
Denise Gamé, Juli Bassas, Cristina Grau, Carlos Ferrándiz, José Manuel Carrascosa
Fixed eruptions are a group of inflammatory dermatoses characterized by recurrent episodes of lesions affecting the same site or sites on exposure to a trigger; most are caused by drugs (fixed drug eruption) but foods can also cause this type of reaction (fixed food eruption)(1) . With only a few cases described, fixed sunlight eruption (FSE), characterized primarily by skin lesions that recur at the same anatomic sites upon repeated exposures to sunlight, has been considered to be another variant of these fixed eruptions, with the implication that a drug or food must be involved(2-7) ...
March 31, 2017: Photodermatology, Photoimmunology & Photomedicine
Sophie Momen, Robert Sarkany
The management of vitiligo poses unique challenges due to the lack of effective treatments and the devastating impact of vitiligo, especially in dark-skinned patients. Treatment response is slow, and the risk of relapse after successful treatment is high. Patients may require multiple courses of Narrowband UVB (NBUVB), resulting in very high cumulative doses of UVB1. Using data from animal studies NBUVB is considered to be a safer than PUVA(2) . This article is protected by copyright. All rights reserved.
March 28, 2017: Photodermatology, Photoimmunology & Photomedicine
Kai-Chi Tsai, Jen-Hung Yang, Sung-Jen Hung
Fenofibrate, a fibric acid derivative, is among the most commonly used antihyperlipidemic medications. The most common side effects are gastrointestinal problems, including abdominal discomfort, diarrhea, and constipation. While cutaneous eruption occurred in 2% of fenofibrate users(1) , photosensitivity is a rare manifestation. Jeanmougin et al. presented the first case of fenofibrate induced photosensitivity in 1983.(2) Herein we report 4 cases of fenofibrate-induced photosensitization with different types of cutaneous eruptions as papulovesicular, lichenoid, and sunburn-like rashes, and one among them was confirmed by photopatch testing...
March 20, 2017: Photodermatology, Photoimmunology & Photomedicine
Min-Young Park, Woo-Haing Shim, Jeong-Min Kim, Gun-Wook Kim, Hoon-Soo Kim, Hyun-Chang Ko, Moon-Bum Kim, Byung-Soo Kim
No abstract text is available yet for this article.
March 4, 2017: Photodermatology, Photoimmunology & Photomedicine
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Photodermatology, Photoimmunology & Photomedicine
Walter Liszewski, David Gram Naym, Edyta Biskup, Robert Gniadecki
BACKGROUND: Photochemotherapy with psoralen and ultraviolet A (PUVA), with or without adjuvant interferon-α (IFN-α), is a first-line therapy for early-stage mycosis fungoides and other forms of cutaneous T-cell lymphoma (CTCL). However, the mechanism by which PUVA with IFN-α work in CTCL is poorly understood. PURPOSE: To develop a model to investigate the mechanisms of PUVA and PUVA with IFN-α in CTCL cells. METHODS: An in vitro model to study the molecular mechanisms of PUVA was created using two different CTCL cell lines, MyLa, which has functional p53, and HuT-78, in which p53 is inactivated due to a homozygous nonsense mutation...
May 2017: Photodermatology, Photoimmunology & Photomedicine
Roisin A Hambly, Nazish Mansoor, Catherine Quinlan, Zahra Shah, Patsy Lenane, Nicola Ralph, Fergal J Moloney
No abstract text is available yet for this article.
May 2017: Photodermatology, Photoimmunology & Photomedicine
Catherine M Olsen, Louise F Wilson, Adèle C Green, Neela Biswas, Juhi Loyalka, David C Whiteman
BACKGROUND/PURPOSE: There is strong evidence that topical sunscreens, designed to protect against ultraviolet radiation (UVR)-induced erythema, decrease the amount of UVR to which the skin is exposed, but their effectiveness in reducing UVR-induced DNA damage in vivo has not been well quantified. METHODS: We systematically reviewed the published literature (1990-2015) to determine whether sunscreens prevent DNA damage in human skin when applied prior to UVR exposure...
May 2017: Photodermatology, Photoimmunology & Photomedicine
Izumi Kishimoto, Naoko Uetsu, Hirotsugu Tanimura, Hidetaka Fujii, Hiroyuki Okamoto
No abstract text is available yet for this article.
May 2017: Photodermatology, Photoimmunology & Photomedicine
Paola Torricelli, Milena Fini, Pier Alessandro Fanti, Emi Dika, Massimo Milani
BACKGROUND: Polypodium leucotomos (PL) exerts potent antioxidant, photo-protective, and immune-modulatory activities. A reconstructed human epidermis (RHE) (Episkin) is a suitable model for the evaluation of acute UV-induced cell damage. No data regarding the photo-protective action of PL in this model are available. PURPOSE: We evaluated the effects of PL on the prevention of UVB-induced cell damage assessing sunburn cells, CPD formation, p53, Ki-67, p21 expression, and epidermal growth factor (EGF) production...
May 2017: Photodermatology, Photoimmunology & Photomedicine
Sevgi Akarsu, Ozlem Ozbagcivan, Turna Ilknur, Fatma Semiz, Emel Fetil
BACKGROUND/PURPOSE: There are no data comprehensively investigating the key beliefs and sun protection behaviours in patients with actinic keratosis (AK). Our aim was to determine and correlate the AK perceptions and readiness to increase sun protection (RISP) behaviours. METHODS: AK patients' (n = 200) demographics and clinical findings were recorded. Participants completed questionnaires (Illness Perception Questionnaire-Revised and RISP behaviours scales). RESULTS: The mean scores of giving up sunbathing of the patients aged <65 years, and giving up sunbathing and staying in the shade behaviours of females were higher...
May 2017: Photodermatology, Photoimmunology & Photomedicine
Neha Kumar, Christine B Warren
Photodynamic therapy (PDT), using topical aminolevulinic acid (ALA), has been used for years to treat a variety of dermatologic conditions, including actinic keratosis, superficial basal cell carcinoma, and in situ squamous cell carcinoma. While there is a wide range of neoplastic and non-neoplastic skin diseases for which ALA-PDT is used in adults, there is a knowledge gap when it comes to its use in children. This review highlights what is currently known regarding the use and efficacy of this therapy in the pediatric population...
May 2017: Photodermatology, Photoimmunology & Photomedicine
Hae Jeong Youn, Ki Bbeum Kim, Hyo-Sun Han, In-Sook An, Kyu Joong Ahn
BACKGROUND: Ultraviolet A (UVA), one of the major components of sunlight, can penetrate the dermal layer of the skin and generate reactive oxygen species (ROS). It causes alterations in the dermal connective tissue and gene expression, inflammation, photoaging, and DNA damage. AIMS: Therefore, the harmful effects of UVA and strategies to reduce it have been consistently investigated. 23-Hydroxytormentic acid (23-HTA) has been demonstrated to improve drug-induced nephrotoxicity and exhibit several free radical scavenging effects with other molecules...
March 2017: Photodermatology, Photoimmunology & Photomedicine
Michael C Kirchberger, Markus V Heppt, Thomas K Eigentler, Markus A Kirchberger, Gerold Schuler, Lucie Heinzerling
BACKGROUND: The incidence of melanoma has been rising worldwide. One possible reason for this is natural and artificial UV exposure. Only little data on actual consumer statistics from tanning studios and the usage of sunscreen are available. Therefore, it is difficult to describe trends for both and identify the impact of preventive measures. METHODS: To gain knowledge about the popularity of 'tanning bed' and 'sunscreen', normalized search volumes for both search queries were obtained from Google Trends for 11 countries between January 2004 and June 2016...
March 2017: Photodermatology, Photoimmunology & Photomedicine
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