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Photodermatology, Photoimmunology & Photomedicine

Tasneem F Mohammad, Narumol Silpa-Archa, James L Griffith, Henry W Lim, Iltefat H Hamzavi
Vitiligo is a disorder characterized by the development of depigmented macules and patches. Narrowband ultraviolet B phototherapy is a standard of care treatment and is used both as monotherapy and in combination with other treatment modalities to induce repigmentation. Although phototherapy is safe and effective, its use is limited due to the significant time commitment required and associated costs. Home phototherapy is a safe and effective alternative to make phototherapy more accessible to patients. However, it is often underutilized due to lack of physician experience and comfort as well as misconceptions regarding its safety and efficacy...
June 16, 2017: Photodermatology, Photoimmunology & Photomedicine
Ishita Dua, Kamal Aggarwal, V K Jain
BACKGROUND: Vitamin D analogues and NBUVB phototherapy are both well-established modalities of treatment in psoriasis. The objective of this open label, intra individual, left right study was to compare two different Vitamin D analogues, calcipotriol and tacalcitol, in combination with NBUVB phototherapy in chronic stable plaque psoriasis. METHODS: Thirty patients with stable plaque psoriasis were enrolled for a 12 week clinical trial. The target lesion on left side was treated topically with tacalcitol ointment once daily, while that on the right side was treated with calcipotriol ointment twice daily...
June 11, 2017: Photodermatology, Photoimmunology & Photomedicine
L Duteil, J Esdaile, Y Maubert, A Cathelineau, A Bouloc, C Queille-Roussel, T Passeron
BACKGROUND: Until now, photoprotection of human skin has involved the development of sunscreens effective in the ultraviolet (UV) domain. During the last ten years several studies have shown that besides the well-known damaging effects of UV, visible (400-700nm) and even infrared light (> 700 nm) can induce damage which contributes to photoaging. Furthermore, many photodermatoses are also known to be triggered by visible light (VL). OBJECTIVE/ METHOD: An in vivo method is proposed to assess the protective efficacy of sunscreens in the VL domain...
June 11, 2017: Photodermatology, Photoimmunology & Photomedicine
Catriona P Harkins, Alex J Waters, Robert S Dawe, James Ferguson, Sally H Ibbotson
Polymorphic light eruption (PLE) affects 18% of people in Northern Europe. It is characterised by a delayed-onset pruritic photo-exposed site papular eruption after sun exposure.There is considerable heterogeneity in presentation, morphology and severity. This article is protected by copyright. All rights reserved.
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
Daniel Morgado-Carrasco, José Riera-Monroig, Xavier Fustà-Novell, Sebastian Podlipnik, Paula Aguilera
Aquagenic pruritus (AP) is a rare skin disease of unknown aetiology characterized by the abrupt onset of pruritus without visible cutaneous lesions after contact with water or humidity. AP can have a severe impact on the patient's quality of life. Although AP is mostly idiopathic, it can be associated with polycythemia vera, other hematologic disorders and medications (1). Treatment is challenging and often disappointing, and may consist in topical agents such as capsaicin 0.025-1.0%, alkaline baths and glycerol trinitrate 2%...
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
X Fustà-Novell, S Podlipnik, A Combalia, D Morgado-Carrasco, J Ferrando, J M Mascaró, P Aguilera
BACKGROUND: Porokeratosis ptychotropica (PP) is a rare variant of porokeratosis with a special predisposition to affect body folds, particularly the intergluteal cleft. This disease is resistant to most topical and systemic treatments reported, as shown in the review of the literature we provide here. Itching and discomfort are often a difficult problem to solve. PATIENTS AND METHODS: Two patients with PP that had not responded to multiple topical treatments were treated with photodynamic therapy (PDT)...
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
Jing Yang, Xiaohong Guo, Xiaorong Tong, Juan Tao
BACKGROUND: Multi-wavelength lasers are reportedly useful for treating venous lake (VL) in Caucasian patients. However, the same parameters may not be safe for Asian patients with Fitzpatrick skin type (FST) IV. PURPOSE: Report experience with using multi-wavelength laser for VL treatment in Asian patients with FST IV. METHODS: Seventeen episodes of VL in 15 Chinese patients with FST IV were treated. 595-nm pulsed dye (PDL) laser followed by 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser were administered...
May 24, 2017: Photodermatology, Photoimmunology & Photomedicine
Young Jae Kim, Sun Young Choi, Woo Jin Lee, Chong Hyun Won, Sung Eun Chang, Jee Ho Choi, Mi Woo Lee
Hydroa vacciniforme-like lymphoproliferative disease (HVLL) was first described as the coexistence of hydroa vacciniforme and malignant lymphoma in 1986. It was renamed in the 2008 World Health Organization classification system as one of the Epstein-Barr virus (EBV)-associated lymphoproliferative diseases (LPDs) of childhood. HVLL has T cell monoclonality and is considered a rare EBV(+) cutaneous T cell lymphoproliferative disease. HVLL occurs predominantly in children and young adults of Asia and Latin America,(1, 2) and are characterised by papulovesicular eruptions, facial edema, ulceration, and atrophic scars similar to hydroa vacciniforme (HV)...
May 24, 2017: Photodermatology, Photoimmunology & Photomedicine
Jose-Manuel Carrascosa, Nuria Floriach, Elisabet Sala, Jose Aguilera
In recent years, there has been a growing interest in the use of naturally occurring substances with antioxidant and/or photoprotective effects to complement solar filters in strategies designed to minimise the adverse effects of ultraviolet radiation (UVR) because of the potential benefits that could be obtained with such ingredients without interfering with vitamin D synthesis in the skin. This article is protected by copyright. All rights reserved.
May 15, 2017: Photodermatology, Photoimmunology & Photomedicine
Tae In Kim, Hye-Jin Ahn, In Hye Kang, Ki-Heon Jeong, Nack In Kim, Min Kyung Shin
BACKGROUND: Photodynamic therapy (PDT) has been reported as an effective alternative treatment for patients with acne. PURPOSE: To evaluate the efficacy and safety of DL-PDT in moderate to severe acne and to compare outcomes with those of laser-assisted daylight photodynamic therapy. METHODS: Patients were randomly assigned to either a DL-PDT group (D group) or a fractional laser-assisted DL-PDT group (F group). The outcomes were assessed by measuring acne lesion counts and severity grade at 4, 8, 12, and 16 weeks after therapy commenced...
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
Giedre Bieliauskiene, Peter A Philipsen, Hans Christian Wulf
People's UV sensitivity can be predicted by measuring skin pigmentation (1,2). Constitutive pigmentation is often measured on the inner arm (3,4), but the best suited place is on previously sun-unexposed buttocks, where pigmentation is considered to be constant throughout life. However, this anatomical site is not as easily accessible as the inner arm, and it is less convenient to use in large-scale studies. There are indications that pigmentation measurements on buttocks skin and inner arm are not interchangeable (5), and it is unclear if the inner arm can be used for measurement of constitutive pigmentation...
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
T Gracia Cazaña, S González, A Juarranz, Y Gilaberte
Basal cell carcinoma (BCC) is the most common skin cancer, with an incidence rate in Spain of 113.05 cases per 100 000 person-years (CI95%, 89.03-137.08).(1) Pigmented BCCs (pBCCs), is a clinical and histological variant of BCC that exhibits increased pigmentation. pBCCs account for 6.7% to 8.5% of BCCs, and show a racial predilection.(2-3) This article is protected by copyright. All rights reserved.
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
David Rutkowski, Mark D Farrar, Joanne E Osman, Ann R Webb, Lesley E Rhodes
BACKGROUND: Solar UVR is a major cause of skin cancer but also an important source of vitamin D (VitD), essential for musculoskeletal health. Conflicting public health messages may confuse patients with skin cancer prone to further skin cancer. OBJECTIVE: To explore the knowledge, behaviour and attitudes of patients with skin cancer to sunlight exposure and VitD sources. METHODS: Patients (n = 10) previously treated for multiple basal cell cancer in a hospital setting participated in focus group sessions with semi-structured discussions to explore: knowledge of VitD, sun-avoidance behaviour and attitude towards sunlight exposure messages...
April 27, 2017: Photodermatology, Photoimmunology & Photomedicine
Arif Aslam, Lynn Fullerton, Sally Helen Ibbotson
No abstract text is available yet for this article.
April 17, 2017: Photodermatology, Photoimmunology & Photomedicine
Denise Gamé, Juli Bassas, Cristina Grau, Carlos Ferrándiz, José Manuel Carrascosa
Fixed eruptions are a group of inflammatory dermatoses characterized by recurrent episodes of lesions affecting the same site or sites on exposure to a trigger; most are caused by drugs (fixed drug eruption) but foods can also cause this type of reaction (fixed food eruption)(1) . With only a few cases described, fixed sunlight eruption (FSE), characterized primarily by skin lesions that recur at the same anatomic sites upon repeated exposures to sunlight, has been considered to be another variant of these fixed eruptions, with the implication that a drug or food must be involved(2-7) ...
March 31, 2017: Photodermatology, Photoimmunology & Photomedicine
Sophie Momen, Robert Sarkany
No abstract text is available yet for this article.
March 28, 2017: Photodermatology, Photoimmunology & Photomedicine
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Photodermatology, Photoimmunology & Photomedicine
Walter Liszewski, David Gram Naym, Edyta Biskup, Robert Gniadecki
BACKGROUND: Photochemotherapy with psoralen and ultraviolet A (PUVA), with or without adjuvant interferon-α (IFN-α), is a first-line therapy for early-stage mycosis fungoides and other forms of cutaneous T-cell lymphoma (CTCL). However, the mechanism by which PUVA with IFN-α work in CTCL is poorly understood. PURPOSE: To develop a model to investigate the mechanisms of PUVA and PUVA with IFN-α in CTCL cells. METHODS: An in vitro model to study the molecular mechanisms of PUVA was created using two different CTCL cell lines, MyLa, which has functional p53, and HuT-78, in which p53 is inactivated due to a homozygous nonsense mutation...
May 2017: Photodermatology, Photoimmunology & Photomedicine
Roisin A Hambly, Nazish Mansoor, Catherine Quinlan, Zahra Shah, Patsy Lenane, Nicola Ralph, Fergal J Moloney
No abstract text is available yet for this article.
May 2017: Photodermatology, Photoimmunology & Photomedicine
Catherine M Olsen, Louise F Wilson, Adèle C Green, Neela Biswas, Juhi Loyalka, David C Whiteman
BACKGROUND/PURPOSE: There is strong evidence that topical sunscreens, designed to protect against ultraviolet radiation (UVR)-induced erythema, decrease the amount of UVR to which the skin is exposed, but their effectiveness in reducing UVR-induced DNA damage in vivo has not been well quantified. METHODS: We systematically reviewed the published literature (1990-2015) to determine whether sunscreens prevent DNA damage in human skin when applied prior to UVR exposure...
May 2017: Photodermatology, Photoimmunology & Photomedicine
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