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Photodermatology, Photoimmunology & Photomedicine

Suteeraporn Chaowattanapanit, Charoen Choonhakarn, Chingching Foocharoen, Narachai Julanon
Systemic scleroderma-also known as systemic sclerosis (SSc)-is a chronic systemic connective tissue disease characterized by collagen deposition in cutaneous and internal organs, leading to skin sclerosis and multiple organ fibrosis. The pathogenesis is complex and remains poorly understood. Treatment is based on organ involvement and requires a multidisciplinary approach. Skin sclerosis can cause disability, leading to decreasing quality of life. Various systemic anti-fibrotic therapies have been used; however, most have unsatisfactory results...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
Sonja Radakovic, Adrian Tanew
BACKGROUND: Actinic cheilitis (AC) is a common disease caused by chronic ultraviolet exposure. OBJECTIVE: Alacare is a self-adhesive, skin coloured 5-aminolaevulinic acid (ALA) patch that has been developed for the treatment of mild to moderate actinic keratosis (AK). Considering the good results in the treatment of AK, the standardized delivery of ALA and the simple application Alacare patch PDT appears as an interesting treatment option for AC. METHODS: We retrospectively assessed the efficacy, tolerability and cosmetic outcome of Alacare patch PDT in eleven patients with AC...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
Ashley Sample, Yu-Ying He
Melanoma is the deadliest form of skin cancer and its incidence is rising, creating a costly and significant clinical problem. Exposure to ultraviolet (UV) radiation, namely UVA (315-400 nm) and UVB (280-315 nm), is a major risk factor for melanoma development. Cumulative UV radiation exposure from sunlight or tanning beds contributes to UV-induced DNA damage, oxidative stress, and inflammation in the skin. A number of factors, including hair color, skin type, genetic background, location, and history of tanning, determine the skin's response to UV radiation...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
Rashi Minocha, Diona L Damian, Gary M Halliday
Ultraviolet radiation (UVR) causes DNA damage in melanocytes by producing photolesions such as cyclobutane pyrimidine dimers and 8-oxo-7-hydrodeoxyguanosine. The production of reactive oxygen species by UVR also induces inflammatory cytokines that, together with the inherent immunosuppressive properties of UVR, propagate carcinogenesis. Nicotinamide (Vitamin B3 ) enhances DNA repair, modulates the inflammatory environment produced by UVR and reduces UV-induced immunosuppression. As nicotinamide reduces the incidence of actinic keratoses and non-melanoma skin cancers in high-risk individuals, and enhances repair of DNA damage in melanocytes, it is a promising agent for the chemoprevention of melanoma in high-risk populations...
July 5, 2017: Photodermatology, Photoimmunology & Photomedicine
Alessia Pacifico, Giovanni Leone, Giovanni Damiani, Carmela Ferraro, Paolo Iacovelli, Andrea Paro Vidolin, Luca Muscardin
Neoplasms of histiocytes, as well as of dendritic cells-derived, are rare entities and all of them derived from a common medullar progenitor CD34(+) . Recently, histiocytosis were grouped and re-classified in the following entities: histiocytic sarcoma, tumours derived from Langerhans cells, interdigitating dendritic cell sarcoma and the follicular dendritic cell sarcoma; furthermore, two more rare entities have been described:fibroblastic reticular cell tumour and the indeterminate dendritic cell tumour. This article is protected by copyright...
June 29, 2017: Photodermatology, Photoimmunology & Photomedicine
Jean-Claire P Dillon, ChiAyrsh Ford, Linda S Hynan, Amit G Pandya
Narrowband ultraviolet B (NB-UVB) phototherapy is an effective treatment for vitiligo, resulting in up to 75% repigmentation in 9 months, however, compliance is often poor due to the economic burden and inconvenience associated with this form of therapy. Home phototherapy has been shown to be an effective treatment for a variety of skin conditions, including vitiligo. Despite this evidence, home phototherapy for vitiligo is considered experimental and investigational by health insurance providers. This article is protected by copyright...
June 29, 2017: Photodermatology, Photoimmunology & Photomedicine
Tasneem F Mohammad, Narumol Silpa-Archa, James L Griffith, Henry W Lim, Iltefat H Hamzavi
Vitiligo is a disorder characterized by the development of depigmented macules and patches. Narrowband ultraviolet B phototherapy is a standard of care treatment and is used both as monotherapy and in combination with other treatment modalities to induce repigmentation. Although phototherapy is safe and effective, its use is limited due to the significant time commitment required and associated costs. Home phototherapy is a safe and effective alternative to make phototherapy more accessible to patients. However, it is often underutilized due to lack of physician experience and comfort as well as misconceptions regarding its safety and efficacy...
June 16, 2017: Photodermatology, Photoimmunology & Photomedicine
Ishita Dua, Kamal Aggarwal, V K Jain
BACKGROUND: Vitamin D analogues and NBUVB phototherapy are both well-established modalities of treatment in psoriasis. The objective of this open label, intra individual, left right study was to compare two different Vitamin D analogues, calcipotriol and tacalcitol, in combination with NBUVB phototherapy in chronic stable plaque psoriasis. METHODS: Thirty patients with stable plaque psoriasis were enrolled for a 12 week clinical trial. The target lesion on left side was treated topically with tacalcitol ointment once daily, while that on the right side was treated with calcipotriol ointment twice daily...
June 11, 2017: Photodermatology, Photoimmunology & Photomedicine
Luc Duteil, Jane Esdaile, Yves Maubert, Anne-Claire Cathelineau, Anne Bouloc, Catherine Queille-Roussel, Thierry Passeron
BACKGROUND: Until now, photoprotection of human skin has involved the development of sunscreens effective in the ultraviolet (UV) domain. During the last ten years, several studies have shown that besides the well-known damaging effects of UV, visible (400-700 nm) and even infrared light (> 700 nm) can induce damage which contributes to photoaging. Furthermore, many photodermatoses are also known to be triggered by visible light (VL). OBJECTIVE/METHOD: An in vivo method is proposed to assess the protective efficacy of sunscreens in the VL domain...
June 11, 2017: Photodermatology, Photoimmunology & Photomedicine
Catriona P Harkins, Alex J Waters, Robert S Dawe, James Ferguson, Sally H Ibbotson
Polymorphic light eruption (PLE) affects 18% of people in Northern Europe. It is characterised by a delayed-onset pruritic photo-exposed site papular eruption after sun exposure.There is considerable heterogeneity in presentation, morphology and severity. This article is protected by copyright. All rights reserved.
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
Daniel Morgado-Carrasco, José Riera-Monroig, Xavier Fustà-Novell, Sebastian Podlipnik, Paula Aguilera
Aquagenic pruritus (AP) is a rare skin disease of unknown aetiology characterized by the abrupt onset of pruritus without visible cutaneous lesions after contact with water or humidity. AP can have a severe impact on the patient's quality of life. Although AP is mostly idiopathic, it can be associated with polycythemia vera, other hematologic disorders and medications (1). Treatment is challenging and often disappointing, and may consist in topical agents such as capsaicin 0.025-1.0%, alkaline baths and glycerol trinitrate 2%...
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
X Fustà-Novell, S Podlipnik, A Combalia, D Morgado-Carrasco, J Ferrando, J M Mascaró, P Aguilera
BACKGROUND: Porokeratosis ptychotropica (PP) is a rare variant of porokeratosis with a special predisposition to affect body folds, particularly the intergluteal cleft. This disease is resistant to most topical and systemic treatments reported, as shown in the review of the literature we provide here. Itching and discomfort are often a difficult problem to solve. PATIENTS AND METHODS: Two patients with PP that had not responded to multiple topical treatments were treated with photodynamic therapy (PDT)...
June 5, 2017: Photodermatology, Photoimmunology & Photomedicine
Jing Yang, Xiaohong Guo, Xiaorong Tong, Juan Tao
BACKGROUND: Multi-wavelength lasers are reportedly useful for treating venous lake (VL) in Caucasian patients. However, the same parameters may not be safe for Asian patients with Fitzpatrick skin type (FST) IV. PURPOSE: Report experience with using multi-wavelength laser for VL treatment in Asian patients with FST IV. METHODS: Seventeen episodes of VL in 15 Chinese patients with FST IV were treated. 595-nm pulsed dye (PDL) laser followed by 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser were administered...
May 24, 2017: Photodermatology, Photoimmunology & Photomedicine
Young Jae Kim, Sun Young Choi, Woo Jin Lee, Chong Hyun Won, Sung Eun Chang, Jee Ho Choi, Mi Woo Lee
Hydroa vacciniforme-like lymphoproliferative disease (HVLL) was first described as the coexistence of hydroa vacciniforme and malignant lymphoma in 1986. It was renamed in the 2008 World Health Organization classification system as one of the Epstein-Barr virus (EBV)-associated lymphoproliferative diseases (LPDs) of childhood. HVLL has T cell monoclonality and is considered a rare EBV(+) cutaneous T cell lymphoproliferative disease. HVLL occurs predominantly in children and young adults of Asia and Latin America,(1, 2) and are characterised by papulovesicular eruptions, facial edema, ulceration, and atrophic scars similar to hydroa vacciniforme (HV)...
May 24, 2017: Photodermatology, Photoimmunology & Photomedicine
Jose-Manuel Carrascosa, Nuria Floriach, Elisabet Sala, Jose Aguilera
In recent years, there has been a growing interest in the use of naturally occurring substances with antioxidant and/or photoprotective effects to complement solar filters in strategies designed to minimise the adverse effects of ultraviolet radiation (UVR) because of the potential benefits that could be obtained with such ingredients without interfering with vitamin D synthesis in the skin. This article is protected by copyright. All rights reserved.
May 15, 2017: Photodermatology, Photoimmunology & Photomedicine
Tae In Kim, Hye-Jin Ahn, In Hye Kang, Ki-Heon Jeong, Nack In Kim, Min Kyung Shin
BACKGROUND: Photodynamic therapy (PDT) has been reported as an effective alternative treatment for patients with acne. PURPOSE: To evaluate the efficacy and safety of DL-PDT in moderate to severe acne and to compare outcomes with those of laser-assisted daylight photodynamic therapy. METHODS: Patients were randomly assigned to either a DL-PDT group (D group) or a fractional laser-assisted DL-PDT group (F group). The outcomes were assessed by measuring acne lesion counts and severity grade at 4, 8, 12, and 16 weeks after therapy commenced...
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
Giedre Bieliauskiene, Peter A Philipsen, Hans Christian Wulf
No abstract text is available yet for this article.
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
Tamara Gracia-Cazaña, Salvador González, Angeles Juarranz, Yolanda Gilaberte
No abstract text is available yet for this article.
May 13, 2017: Photodermatology, Photoimmunology & Photomedicine
David Rutkowski, Mark D Farrar, Joanne E Osman, Ann R Webb, Lesley E Rhodes
BACKGROUND: Solar UVR is a major cause of skin cancer but also an important source of vitamin D (VitD), essential for musculoskeletal health. Conflicting public health messages may confuse patients with skin cancer prone to further skin cancer. OBJECTIVE: To explore the knowledge, behaviour and attitudes of patients with skin cancer to sunlight exposure and VitD sources. METHODS: Patients (n = 10) previously treated for multiple basal cell cancer in a hospital setting participated in focus group sessions with semi-structured discussions to explore: knowledge of VitD, sun-avoidance behaviour and attitude towards sunlight exposure messages...
April 27, 2017: Photodermatology, Photoimmunology & Photomedicine
Thomas M Rünger, Li-Fang Wang, Cheng-Che E Lan
No abstract text is available yet for this article.
July 2017: Photodermatology, Photoimmunology & Photomedicine
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