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Photodermatology, Photoimmunology & Photomedicine

Julian Boix-Vilanova, Juan Escalas, Ana Martin-Santiago, Oriol Corral-Magaña
Mycosis fungoides (MF) is the most common cutaneous T cell lymphoma (CTCL). Generally it affects patients over 50 years of age being rare in children. Its clinical presentation is very heterogeneous with several clinicopathological variants. The treatment of MF depends on its stage, variant and the characteristics of the patient. This article is protected by copyright. All rights reserved.
July 14, 2018: Photodermatology, Photoimmunology & Photomedicine
C Nicklas, R Rubio, C Cárdenas, A Hasson
BACKGROUND: Although progress has been made in the study of photodynamic therapy for acne, studies using current recommended therapies as active comparators are lacking. METHODS: Randomized, controlled trial involving 46 patients with moderate inflammatory facial acne, 23 patients received two sessions of PDT separated by 2 weeks (ALA20% incubated 1.5 hours before red light irradiation with 37J/cm2 fluence) and 23 patients received doxycycline 100mg/day plus adapalene gel 0...
July 11, 2018: Photodermatology, Photoimmunology & Photomedicine
Zhenping Wang, Jae-Eun Choi, Chia-Chi Wu, Anna Di Nardo
BACKGROUND/PURPOSE: Skin commensal bacteria have been described to help orchestrate skin homeostasis, signaling through innate immunity pathways. This study for the first time aimed at studying the relationship between skin commensals and melanocytes after UVB exposure. METHODS: An in vitro UVB radiation model with normal human epidermal melanocytes (NHMs) and skin commensal bacteria supernatant from S. epidermidis and P. acnes was established. Melanocytes DNA damage, cyclobutane pyrimidine dimers (CPD), and cellular proliferation marker Ki-67 were measured by ELISA and immunofluorescence staining...
July 5, 2018: Photodermatology, Photoimmunology & Photomedicine
Barbara Hernando, Elena Sanz-Page, Gerard Pitarch, Laura Mahiques, Francisca Valcuende-Cavero, Conrado Martínez-Cadenas
BACKGROUND/PURPOSE: Recent GWAS studies, mostly performed in populations of North European origin, have identified the genetic loci associated with pigmentation, sun sensitivity, freckling, and skin cancer susceptibility. Here we aimed at addressing the genetic determinants of sunlight sensitivity in Spain, a southern European population. METHODS: Nine SNPs located in 8 pigmentation-related genes (IRF4, TYR, ASP, HERC2, OCA2, BNC2, SLC24A4 and SLC45A2) were genotyped in 456 Spaniards...
July 5, 2018: Photodermatology, Photoimmunology & Photomedicine
Lok Chin Wong, Adawiyah Jamil, Norazirah Md Nor
BACKGROUND: Ethnicity, skin phototype and colour influenced minimal erythema dose (MED). Sun exposure has been postulated to increase MED. We determined immediate pigment darkening dose to UVA (IPDDA), MED and minimal melanogenic dose (MMD) for UVB and UVA, and investigated factors affecting these doses. METHODS: Skin phototype was determined using Fitzpatrick phototype quiz, DSMII ColorMeter measured skin colours, sun exposure quantified using an index (SEI) and phototest performed with MEDlight-Multitester...
June 28, 2018: Photodermatology, Photoimmunology & Photomedicine
Therdpong Tempark, Suparuj Lueangarun, Susheera Chatproedprai, Ratchathorn Panchaprateep, Marisa Pongprutthipan, Siriwan Wananukul
BACKGROUND: Limited data of sun protection knowledge in laser treatment patients exists therefore, preventative information should be provided by dermatologists to minimize harmful effects. OBJECTIVE: To assess sun protection knowledge-behavior and knowledge to prevent adverse events from laser therapy among patients who visited a laser clinic at a tertiary university hospital in Bangkok, Thailand. METHODS: This is a self-reported questionnaire, cross-sectional survey...
June 22, 2018: Photodermatology, Photoimmunology & Photomedicine
Ho-Jin Kim, Ki-Ho Kim
BACKGROUND: Chronic actinic dermatitis (CAD) develops in seasons where there is high sun exposure, such as summer, and can persistent throughout the year in severely affected cases. The authors noted that CAD prevalence increased in relation to climate changes and air pollutants. METHODS: We retrospectively analyzed 294 patients with newly diagnosed CAD between December 2000 and November 2016. We investigated the annual trend of sun hours, humidity, and ground-level ozone and respirable particles (PM10) in Pusan, Korea; correlations between climate change and/or air pollution and the incidence of patient with CAD were analyzed...
June 11, 2018: Photodermatology, Photoimmunology & Photomedicine
Alesia M Jung, Leslie K Dennis, Elizabeth T Jacobs, Georg T Wondrak
BACKGROUND/PURPOSE: Sun sensitivity, a confounder between sun exposure and sun protection, is often overlooked. We examined how sun exposure and sun protection behaviors among indoor workers varied by sun sensitivity. METHODS: Sun exposure and sun protection diaries over a 45-day period from Midwestern United States indoor workers were examined. We categorized sun sensitivity (fair and non-fair complexion) using tanning inability and sunburn tendency. Total exposure (sunrise to sunset) and peak exposure (10 am and 4 pm) lasting at least 60 minutes were examined...
June 11, 2018: Photodermatology, Photoimmunology & Photomedicine
Giedre Bieliauskiene, Peter A Philipsen, Hans Christian Wulf
BACKGROUND/PURPOSE: Skin phototype questionnaires usually ask similar questions, but they differ in how the answers can be given. There is either one combined answer, which includes both tendency to burn and ability to tan, or 2 separate answers about burn and tan, respectively. We tested the reproducibility of different questionnaires and their relation to objectively measured skin phototype. METHOD: A total of 149 participants completed 3 skin phototype questionnaires distributed twice with median 3 months interval: (i) a Fitzpatrick questionnaire (FST-q) with combined answers about tendency to burn and ability to tan, (ii) a detailed questionnaire (Detail-q) with separate answers to 2 detailed questions about burn and tan and (iii) a short questionnaire (Short-q) with separate answers to 2 simplified questions about burn and tan...
June 8, 2018: Photodermatology, Photoimmunology & Photomedicine
Nahla Shihab, Henry W Lim
The increased use of ultraviolet (UV) nail lamps in recent years has generated safety concerns of this device. A UV nail lamp is a source of artificial UVA radiation, often used to dry, harden, and cure the nails at home and in the salon. UVA radiation is known to be mutagenic and can cause damage to the DNA, resulting in cutaneous malignancy. Currently, there are only a few studies that have evaluated UV nail lamp irradiation and its potential carcinogenic risk. We review the literature on UV nail lamps, its safety, effect on nails and hands, and the potential role in increasing the risk of cutaneous malignancy...
June 8, 2018: Photodermatology, Photoimmunology & Photomedicine
Bistra I Veleva, Rutger L van Bezooijen, Victor G M Chel, Mattijs E Numans, Monique A A Caljouw
BACKGROUND: Human and animal studies have shown that exposure to ultraviolet light can incite a chain of endocrine, immunologic, and neurohumoral reactions that might affect mood. This review focuses on the evidence from clinical trials and observational studies on the effect of ultraviolet light on mood, depressive disorders, and well-being. METHODS: A search was made in PubMed, Embase, Web of Science, Cochrane, Psychinfo, CINAHL, Academic Search Premier and Science Direct, and the references of key papers, for clinical trials and observational studies describing the effect of ultraviolet light applied to skin or eyes on mood, depressive disorders, and well-being...
June 1, 2018: Photodermatology, Photoimmunology & Photomedicine
Iris Amitay-Laish, Batya Davidovici, Lilach Moyal, Michael Gurevich, Lehavit Akerman, Emmilia Hodak
No abstract text is available yet for this article.
May 31, 2018: Photodermatology, Photoimmunology & Photomedicine
Randa Youssef, Mona R E Abdel-Halim, Marwa Kamel, Mervat Khorshid, Aya Fahim
No abstract text is available yet for this article.
May 15, 2018: Photodermatology, Photoimmunology & Photomedicine
Oscar Zaar, Alexandra Sjöholm Hylén, Martin Gillstedt, John Paoli
BACKGROUND: Photodynamic therapy (PDT) can be used to treat large fields of actinic keratoses (AKs) with high clearance rates. A notable downside is the amount of pain that accompany the treatment. This study aimed to optimize the illumination protocol during conventional PDT in order to reduce pain without compromising treatment effectiveness. METHODS: In this prospective, randomized study with a split-face design, patients with, symmetrically distributed AKs were included...
May 12, 2018: Photodermatology, Photoimmunology & Photomedicine
Anke König, Svenja Missalla, Eva M Valesky, August Bernd, Roland Kaufmann, Stefan Kippenberger, Nadja N Zöller
No abstract text is available yet for this article.
April 26, 2018: Photodermatology, Photoimmunology & Photomedicine
Akimichi Morita
No abstract text is available yet for this article.
May 2018: Photodermatology, Photoimmunology & Photomedicine
Keiichi Hiramoto, Yurika Yamate, Satoshi Yokoyama
BACKGROUND: Ultraviolet (UV) B irradiation has been shown to improve atopic dermatitis (AD). However, the relationship between UVB eye irradiation and AD is not known. This issue was addressed using a mouse model of AD. METHODS: The eyes of NC/Nga mice were irradiated with UVB at a dose of 1.0 kJ/m2 using a 20SE sunlamp for the duration of the experimental period. RESULTS: AD symptoms deteriorated upon UVB eye irradiation. The levels of adrenocorticotropic hormone (ACTH) in the plasma and nucleotide-binding domain and leucine-rich-containing family, pyrin domain-containing (NLRP)3 and neutrophil markers in the skin were increased in UVB-irradiated mice...
May 2018: Photodermatology, Photoimmunology & Photomedicine
Zohaib Akram, Fawad Javed, Mervyn Hosein, Mohammed A Al-Qahtani, Fayez Alshehri, Ahmed I Alzahrani, Fahim Vohra
BACKGROUND: The aim of this systematic review was to assess the efficacy of photodynamic therapy (PDT) in the treatment of symptomatic oral lichen planus (OLP). METHODS: This systematic review aimed to address the following focused question: "Is PDT effective in the treatment of symptomatic OLP?" Indexed databases such as MEDLINE, EMBASE, and CENTRAL were searched up to and including August 2017. RESULTS: Six clinical studies were included...
May 2018: Photodermatology, Photoimmunology & Photomedicine
Daniel Morgado-Carrasco, Xavier Fustà-Novell, Sebastian Podlipnik, Andrea Combalia, Paula Aguilera
BACKGROUND: Solar urticaria (SU) is a rare photodermatosis. Treatment is challenging, and outcomes are often disappointing. Omalizumab is an anti-IgE, currently approved for treatment of chronic spontaneous urticaria. We sought to evaluate therapy with omalizumab in refractory SU and describe predictive factors for response. MATERIALS/METHODS: Patients with refractory SU under treatment with omalizumab were included in this study. Clinical outcome was evaluated using the Urticaria Activity Score 7 (UAS7), Dermatology Life Quality Index (DLQI) and Pruritus Visual Analogue Scale (VAS)...
May 2018: Photodermatology, Photoimmunology & Photomedicine
Denise Falcone, Natallia E Uzunbajakava, Frank van Abeelen, Gerrit Oversluizen, Malou Peppelman, Piet E J van Erp, Peter C M van de Kerkhof
BACKGROUND/PURPOSE: While growing evidence supports the therapeutic effect of 453 nm blue light in chronic inflammatory skin diseases, data on its effects on acutely perturbed human skin are scarce. In this study, we investigated the impact of 453 nm narrow-band LED light on healthy skin following acute perturbation. METHODS: Tape stripping and histamine iontophoresis were performed on the forearm of 22 healthy volunteers on 2 consecutive weeks. In 1 week, challenges were followed by irradiation for 30 minutes...
May 2018: Photodermatology, Photoimmunology & Photomedicine
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