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Photodermatology, Photoimmunology & Photomedicine

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https://www.readbyqxmd.com/read/30414203/topical-treatment-with-a-cathepsin-g-inhibitor-%C3%AE-keto-phosphonic-acid-blocks-ultraviolet-irradiation-induced-basement-membrane-damage-in-hairless-mouse-skin
#1
Novi Kusumaningrum, Jang-Hee Oh, Dong Hun Lee, Chang-Yup Shin, Jee-Hee Jang, Yeon Kyung Kim, Jin Ho Chung
BACKGROUND: Ultraviolet light (UV) exposure contributes various effects to skin including damage of the basement membrane. Cathepsin G (CTSG) belongs to serine protease family and its upregulation is involved in wrinkle formation by chronic UV irradiation. However, the effect of CTSG on the basement membrane damage in skin remains unclear. PURPOSE: To investigate the effects of topical treatment with a CTSG inhibitor, β-keto-phosphonic acid (KPA), on basement membrane damage in chronically UV-irradiated hairless mouse skin...
November 10, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30383894/patient-knowledge-of-fda-mandated-sunscreen-labeling-terminology-a-cross-sectional-survey
#2
Giselle Prado, Ryan M Svoboda, Rebeca W Teplitz, Aaron S Farberg, Darrell S Rigel
BACKGROUND: Insufficient understanding of sunscreen labeling terminology is a barrier to effective use. The FDA issued the "final rule" on sunscreen labeling in 2011, in an effort to promote effective usage. However, relatively little is known about patient knowledge of sunscreen labeling terminology. This study assesses the sunscreen labeling knowledge of dermatology patients, with an emphasis on understanding of the FDA-mandated wording. METHODS: A validated survey was administered to consecutive dermatology office patients...
November 1, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30381854/a-retrospective-cohort-study-of-melanoma-prevalence-stratified-by-body-site-in-a-regional-australian-population-1994-2017-site-specific-protective-mechanisms
#3
D Slape, J Tang, R Lawless, I McCrossin, J W Frew
BACKGROUND: Australia has the highest incidence of cutaneous melanoma worldwide. Previous studies have identified some body areas (forearms and dorsal hands) have lower rates of melanoma than expected when compared with other similarly exposed areas, leading to the suggestion that endogenous immunological protective mechanisms in certain body sites may exist. AIMS AND METHODS: We hypothesise that examination of melanoma by body site in a regional Australian setting, would demonstrate no significant variation in the incidence of melanoma across highly sun exposed areas including the head and neck and upper limbs...
November 1, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30372553/actinic-lichen-planus-triggered-by-drug-photosensitivity
#4
LETTER
M Munera-Campos, G Castillo, C Ferrándiz, J M Carrascosa
A 73-year-old Spanish woman with skin phototype II and a history of hypertension and plaque psoriasis attended our clinic in April 2016 for a mild, pruritic and erythematous dermatosis affecting her face and the dorsal aspect of her forearms. The lesions had developed following exposure to sunlight while the patient was being treated with acitretin for plaque psoriasis. Physical examination showed facial erythema and small erythematous papules on the dorsa of the forearms. No abnormalities were observed in the hair, nails or mucosa...
October 29, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30338865/evaluating-patient-responses-to-omalizumab-in-solar-urticaria
#5
LETTER
L L Griffin, A K Haylett, L E Rhodes
Solar urticaria (SU) is characterised by intense pruritus or burning, erythemal flare and whealing, usually beginning within 5-10 minutes of sun-exposure, with considerable impact on quality of life (QoL)(1). Action spectra commonly involve UVA/visible light, and SU may occur year-round or seasonally. First-line management involves photoprotection and H1 antihistamines, but these frequently fail to control. Second-line options of phototherapy, plasmapheresis, immunosuppressive agents and intravenous immunoglobulins, may be unsuitable, unavailable, or entail prolonged immunosuppression in a chronic disorder, or risks through derivation from pooled human plasma...
October 19, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30312498/skin-cancer-phototype-a-new-classification-directly-related-to-skin-cancer-and-based-on-responses-from-2-869-individuals
#6
Ann-Sofie Sonne Holm-Schou, Peter Alshede Philipsen, Hans Christian Wulf
BACKGROUND/PURPOSE: Fitzpatrick phototype (FST) classification (based on ability to tan and tendency to burn) is widely used for evaluating skin cancer risk; however, it was not developed for that purpose and has been criticised scientifically. The purpose of the present study was a first approach in establishing a new skin cancer phototype (SCP) classification with direct relation to skin cancer risk, based on the questions originally proposed by Fitzpatrick. However, contrary to Fitzpatrick the questions are in the present study kept separate...
October 12, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30290023/low-irradiance-compared-with-conventional-photodynamic-therapy-in-the-treatment-of-actinic-keratoses
#7
Patrick Gholam, Ina Bosselmann, Alexander H Enk, Julika Dick
BACKGROUND: Photodynamic therapy (PDT) is an effective therapy treating photodamaged areas with multiple actinic keratoses (AK). Still pain during therapy is one of the most challenging obstacles for patients. This retrospective study compares pain and efficacy intra-individual in patients using conventional PDT (c-PDT) compared to a low irradiance PDT protocol (li-PDT) with a reduced irradiance to 25% of c-PDT. METHODS: Thirty-one patients were enrolled into this retrospective analysis treated with li-PDT and c-PDT on comparable fields of actinic damage on the forehead or the cheek...
October 5, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30267642/frequency-of-occurrence-of-polymorphic-light-eruption-in-patients-treated-with-photohardening-and-patients-treated-with-phototherapy-for-other-diseases
#8
Alexandra Gruber-Wackernagel, Angelika Hofer, Franz Legat, Peter Wolf
Medical phototherapy can lead to the manifestation of polymorphic light eruption (PLE), though little is known about the frequency of such events. The aim of this Austrian single center study was to retrospectively investigate over a 4-year time period the frequency of PLE in patients prone to the condition and patients with other diseases under phototherapy (mainly narrow-band and broad-band UVB). PLE occurred in 24.3% (18/74) of PLE patients but only 0.7% (3/421) of psoriasis patients under phototherapy (chi-square; p<0...
September 29, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30267591/the-impact-of-positive-antinuclear-antibody-on-narrowband-ultraviolet-b-phototherapy-in-patients-with-vitiligo-a-retrospective-chart-review
#9
Amanda F Nahhas, Nathan T Nartker, Taylor L Braunberger, Gordon Jacobsen, Iltefat H Hamzavi
BACKGROUND/PURPOSE: Screening antinuclear antibody (ANA) is not recommended prior to initiating narrowband ultraviolet B (NBUVB) phototherapy in vitiligo patients, unless concern for photosensitivity exists. Guidelines on prescribing NBUVB phototherapy in vitiligo patients with positive ANA are unavailable, prompting this study to uncover trends. METHODS: This retrospective chart review investigated patients 12 years of age or older with a diagnosis of vitiligo between January 2015 and September 2017, positive serum ANA, and NBUVB phototherapy...
September 29, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30260042/effects-of-extracorporeal-photopheresis-on-serum-levels-of-vitamin-d-preliminary-data-from-a-pilot-study
#10
LETTER
Hannah Kessler, Rodrig Marculescu, Robert Knobler, Christian Jantschitsch
No abstract text is available yet for this article.
September 27, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30251290/comparison-of-uv-protection-properties-of-cotton-fabrics-treated-with-aqueous-and-methanolic-extracts-of-solanum-nigrum-and-amaranthus-viridis-plants
#11
Muhammad Asad Saleem, Ahsan Nazir, Faiza Nazir, Pirah Ayaz, Muhammad Qasim Faizan, Muhammad Usman, Tanveer Hussain
Harmful effects of ultraviolet rays and protection against them have been long discussed. Numerous synthetic dyes, finishes, UV absorbers and Optical brightening agents (OBAs) are present in the market for decades for achieving UV protection through textiles. However, due to environmental impacts of these chemical agents, textile industry is looking for alternatives. In this regard, some natural dyes and plant extracts have shown promising results. However, use of colorless plant extracts as UV protective finishes is still rare...
September 24, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30230620/ultraviolet-b-induced-immunosuppression-is-not-associated-with-rankl-upregulation-in-human-skin
#12
LETTER
Etienne Saint-Cyr Proulx, Shunya Mashiko, Catherine Maari, Chantal Bolduc, Simon Nigen, Marika Sarfati, Robert Bissonnette
Ultraviolet B induced immunosuppression is not associated with RANKL upregulation in human skin. However, expression of amphiregulin is increased by UV-B exposure and its role in UV-induced immunosuppression should be further explored. This article is protected by copyright. All rights reserved.
September 19, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30198587/the-potential-role-of-antioxidants-in-mitigating-skin-hyperpigmentation-resulting-from-ultraviolet-and-visible-light-induced-oxidative-stress
#13
REVIEW
Amanda F Nahhas, Zalfa A Abdel-Malek, Indermeet Kohli, Taylor L Braunberger, Henry W Lim, Iltefat H Hamzavi
Oxidative stress is an integral element that influences a variety of biochemical reactions throughout the body and is known to play a notable role in melanogenesis. Exogenous triggers of oxidative stress, such as ultraviolet radiation (UVR) and visible light (VL), lead to pigment formation through somewhat different pathways, but both share a common endpoint - the potential to generate cosmetically undesirable hyperpigmentation. Though organic and inorganic sunscreens are available to protect against the UVR portion of the electromagnetic spectrum, coverage is lacking to protect against the VL spectrum...
September 10, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30198586/an-international-comparison-of-google-searches-for-sunscreen-sunburn-skin-cancer-and-melanoma-current-trends-and-public-health-implications
#14
Zachary H Hopkins, Aaron M Secrest
BACKGROUND: Google Trends® (GT) offers insight into public interests and behaviors and holds potential for guiding public health campaigns. OBJECTIVES: This study explored international trends in English-speaking countries (United States, United Kingdom, Canada, Australia, New Zealand) in searches for sunscreen, sunburn, skin cancer, and melanoma to better guide skin cancer prevention campaigns. METHODS: Google Trends® was queried for search terms from January 1, 2004 to December 31, 2017...
September 10, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30198585/skin-cancer-projections-and-cost-savings-2014-2045-of-improvements-to-the-danish-sunbed-legislation-of-2014
#15
Brian Køster, Maria K H Meyer, Therese M-L Andersson, Gerda Engholm, Peter Dalum
BACKGROUND: Sunbed use increases the risk of skin cancer. The Danish sunbed-legislation (2014) did not include an age limit. AIM: To model skin cancer incidences and saved costs from potential effects of structural interventions on prevalence of sunbed use. MATERIALS AND METHODS: Survey data from 2015 was collected for 3.999 Danes, representative for the Danish population in regards to age, gender and region. Skin cancer incidences were modelled in the Prevent program, using population projections, historic cancer incidence, sunbed use exposure and relative risk of sunbed use on melanoma...
September 10, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30168611/efficiency-of-methylene-blue-mediated-photodynamic-therapy-vs-intense-pulsed-light-in-the-treatment-of-onychomycosis-in-the-toenails
#16
Enrique Alberdi, Clara Gómez
BACKGROUND: Photodynamic therapy (PDT) or intense pulsed light (IPL) are efficient therapeutic methods in the treatment of superficial skin infections, and thus, they could be good options for onychomycosis treatment, the most common nail disorder. METHODS: Forty patients, affected with different diagnosed types of onychomycosis in nails of the first toe, were randomly divided into two groups of 20 patients to be treated by PDT or IPL. Nail plates were softened with urea 40% by occlusive dressing for 12 hours during 3-7 days before treatments...
August 31, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/30120835/the-enseki-sandbath-a-novel-safe-and-effective-far-infrared-bathing-procedure-for-health
#17
Yoshinori Aragane, Hideaki Higashino
BACKGROUND: Far-infrared (FIR) is well known with various therapeutic benefits. Recently, we have developed a novel FIR bathing system called the Enseki sandbath. In this regard, we focused on physical nature of ceramic to radiate FIR rays when heated adequately. METHODS: A bathtub was filled with ceramic beads and was equipped with computerized system which enabled to supply hot water over the ceramic beads and to drain out when beads were sufficiently heated. This system was used like sandbathing...
August 18, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/29855075/effect-of-ultraviolet-light-on-mood-depressive-disorders-and-well-being
#18
REVIEW
Bistra I Veleva, Rutger L van Bezooijen, Victor G M Chel, Mattijs E Numans, Monique A A Caljouw
BACKGROUND: Human and animal studies have shown that exposure to ultraviolet light can incite a chain of endocrine, immunologic, and neurohumoral reactions that might affect mood. This review focuses on the evidence from clinical trials and observational studies on the effect of ultraviolet light on mood, depressive disorders, and well-being. METHODS: A search was made in PubMed, Embase, Web of Science, Cochrane, Psychinfo, CINAHL, Academic Search Premier and Science Direct, and the references of key papers, for clinical trials and observational studies describing the effect of ultraviolet light applied to skin or eyes on mood, depressive disorders, and well-being...
September 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/29851171/lack-of-detectable-effect-of-narrow-band-ultraviolet-b-on-peripheral-blood-mononuclear-cell-cytokine-expression-in-early-stage-mycosis-fungoides
#19
LETTER
Iris Amitay-Laish, Batya Davidovici, Lilach Moyal, Michael Gurevich, Lehavit Akerman, Emmilia Hodak
No abstract text is available yet for this article.
September 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/29763989/effect-of-polymorphisms-in-il-12b-p40-il-17a-and-il-23-a-g-genes-on-the-response-of-psoriatic-patients-to-narrowband-uvb
#20
LETTER
Randa Youssef, Mona R E Abdel-Halim, Marwa Kamel, Mervat Khorshid, Aya Fahim
No abstract text is available yet for this article.
September 2018: Photodermatology, Photoimmunology & Photomedicine
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