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Photodermatology, Photoimmunology & Photomedicine

Amanda F Nahhas, Zalfa A Abdel-Malek, Indermeet Kohli, Taylor L Braunberger, Henry W Lim, Iltefat H Hamzavi
Oxidative stress is an integral element that influences a variety of biochemical reactions throughout the body and is known to play a notable role in melanogenesis. Exogenous triggers of oxidative stress, such as ultraviolet radiation (UVR) and visible light (VL), lead to pigment formation through somewhat different pathways, but both share a common endpoint - the potential to generate cosmetically undesirable hyperpigmentation. Though organic and inorganic sunscreens are available to protect against the UVR portion of the electromagnetic spectrum, coverage is lacking to protect against the VL spectrum...
September 10, 2018: Photodermatology, Photoimmunology & Photomedicine
Zachary H Hopkins, Aaron M Secrest
BACKGROUND: Google Trends® (GT) offers insight into public interests and behaviors and holds potential for guiding public health campaigns. OBJECTIVES: This study explored international trends in English-speaking countries (United States, United Kingdom, Canada, Australia, New Zealand) in searches for sunscreen, sunburn, skin cancer and melanoma to better guide skin cancer prevention campaigns. METHODS: GT was queried for search terms from 01/01/2004-12/31/2017...
September 10, 2018: Photodermatology, Photoimmunology & Photomedicine
Brian Køster, Maria K H Meyer, Therese M-L Andersson, Gerda Engholm, Peter Dalum
BACKGROUND: Sunbed use increases the risk of skin cancer. The Danish sunbed-legislation (2014) did not include an age limit. AIM: To model skin cancer incidences and saved costs from potential effects of structural interventions on prevalence of sunbed use. MATERIALS AND METHODS: Survey data from 2015 was collected for 3.999 Danes, representative for the Danish population in regards to age, gender and region. Skin cancer incidences were modelled in the Prevent program, using population projections, historic cancer incidence, sunbed use exposure and relative risk of sunbed use on melanoma...
September 10, 2018: Photodermatology, Photoimmunology & Photomedicine
Enrique Alberdi, Clara Gómez
BACKGROUND: Photodynamic therapy (PDT) or Intense Pulsed Light (IPL) are efficient therapeutic methods in the treatment of superficial skin infections and thus they could be good options for Onychomycosis treatment, the most common nail disorder. METHODS: Forty patients, affected with different diagnosed types of Onychomycosis in nails of the first toe, were randomly divided into two groups of 20 patients to be treated by PDT or IPL. Nail plates were softened with urea 40% by occlusive dressing for 12 h during 3-7 days before treatments...
August 31, 2018: Photodermatology, Photoimmunology & Photomedicine
Yoshinori Aragane, Hideaki Higashino
BACKGROUND: Far-infrared (FIR) is well known with various therapeutic benefits. Recently, we have developed a novel FIR bathing system called the Enseki sandbath. In this regard, we focused on physical nature of ceramic to radiate FIR rays when heated adequately. METHODS: A bathtub was filled with ceramic beads and was equipped with computerized system which enabled to supply hot water over the ceramic beads and to drain out when beads were sufficiently heated. This system was used like sandbathing...
August 18, 2018: Photodermatology, Photoimmunology & Photomedicine
Katharina Diehl, Tatiana Görig, Laura Schilling, Rüdiger Greinert, Eckhard W Breitbart, Sven Schneider
BACKGROUND: Sunless tanning products (STPs) are often seen as "healthy alternative" to sunbathing and indoor tanning. However, STP use may entail indirect risks such as overestimating an individual's natural skin type, resulting in risky (natural and artificial) tanning behavior. We aimed to explore STP use in combination with other health-related risk behaviors (eg, smoking), skin cancer risk, risk awareness of ultraviolet radiation, and preventive behavior. METHODS: We used data from the NCAM, a nationwide representative cross-sectional sample (n = 3000, aged 14-45, 48...
August 16, 2018: Photodermatology, Photoimmunology & Photomedicine
Assi Levi, Emmilia Hodak, Claes D Enk, Igor Snast, Dan Slodownik, Moshe Lapidoth
BACKGROUND: Actinic cheilitis (AC) is a common, chronic premalignant condition resulting from protracted sun exposure affecting the vermilion border of the lower lip. Treatment of AC aims at terminating the progression to squamous cell carcinoma by obliterating the primary lesion, and includes ablative methods; nonablative modalities such as cryotherapy, electrodessication, chemical peeling, topical imiquimod and 5-fluorouracil; and photodynamic therapy (PDT). Daylight-activated PDT, in which natural daylight serves as the light source, showed promising results in the treatment of actinic keratoses with substantially less pain than conventional PDT...
July 31, 2018: Photodermatology, Photoimmunology & Photomedicine
Judy Cheng, Rafael Widjajahakim, Susruthi Rajanala, Mayra B C Maymone, Eric Secemsky, Neelam A Vashi
BACKGROUND: Visual imagery has been shown to improve adherence to health messages but has been scarcely investigated in sun-protection campaigns. OBJECTIVE: To determine the effectiveness of photo- and textual-based sun-protective messages in a largely Hispanic population. METHODS: One-hundred forty-five participants received standard of care (SOC) as defined as sun-protective counseling and were then randomized to receive either (a) images of sun-damage, (b) a textual pamphlet about sun damage, or (c) no further messages...
July 29, 2018: Photodermatology, Photoimmunology & Photomedicine
Francesca Larese Filon, Masa Buric, Catharina Fluehler
BACKGROUND: UV exposure is strongly associated with the incidence of non melanoma skin cancers (NMSCs), both basal and squamous cell carcinomas. The aim of our study was to analyze risk perception, UV exposure, preventive habits, and occupation in 126 subjects affected by NMSC and 187 controls. METHODS: Consecutive cases with incident NMSC were recruited in Dermatologic Unit at University of Trieste; controls were recruited in Unit of Occupational Medicine. All had a medical examination to define Fitzpatrick skin type and skin lesions, and filled a standardized questionnaire on sun exposure habits, sun protection, occupational exposures, and sunburns in adulthood and childhood...
July 29, 2018: Photodermatology, Photoimmunology & Photomedicine
Julian Boix-Vilanova, Oriol Corral-Magaña, Ana Martin-Santiago, Juan Escalas
Mycosis Fungoides is the most common cutaneous T-cell lymphoma however, it is rare in children. We present the case of a Folliculotropic Mycosis Fungoides in a 13-year-old boy which initially presented as a plaque on his face and was treated with local PUVA therapy. Afterwards the lesions spread so the treatment was changed to systemic PUVA with good response. Although the experience in the treatment of Mycosis Fungoides in pediatric patients is limited, PUVA therapy seems to be an effective and safe option...
July 14, 2018: Photodermatology, Photoimmunology & Photomedicine
Claudia Nicklas, Rocío Rubio, Consuelo Cárdenas, Ariel Hasson
BACKGROUND: Although progress has been made in the study of photodynamic therapy for acne, studies using current recommended therapies as active comparators are lacking. METHODS: Randomized, controlled trial involving 46 patients with moderate inflammatory facial acne, 23 patients received two sessions of PDT separated by 2 weeks (ALA 20% incubated 1.5 hours before red light irradiation with 37 J/cm2 fluence) and 23 patients received doxycycline 100 mg/d plus adapalene gel 0...
July 11, 2018: Photodermatology, Photoimmunology & Photomedicine
Zhenping Wang, Jae-Eun Choi, Chia-Chi Wu, Anna Di Nardo
BACKGROUND/PURPOSE: Skin commensal bacteria have been described to help orchestrate skin homeostasis, signaling through innate immunity pathways. This study for the first time aimed at studying the relationship between skin commensals and melanocytes after UVB exposure. METHODS: An in vitro UVB radiation model with normal human epidermal melanocytes (NHMs) and skin commensal bacteria supernatant from Staphylococcus epidermidis and Propionibacterium acnes was established...
July 5, 2018: Photodermatology, Photoimmunology & Photomedicine
Barbara Hernando, Elena Sanz-Page, Gerard Pitarch, Laura Mahiques, Francisca Valcuende-Cavero, Conrado Martinez-Cadenas
BACKGROUND/PURPOSE: Recent GWAS studies, mostly performed in populations of North European origin, have identified the genetic loci associated with pigmentation, sun sensitivity, freckling and skin cancer susceptibility. Here, we aimed at addressing the genetic determinants of sunlight sensitivity in Spain, a southern European population. METHODS: Nine SNPs located in 8 pigmentation-related genes (IRF4, TYR, ASP, HERC2, OCA2, BNC2, SLC24A4 and SLC45A2) were genotyped in 456 Spaniards...
July 5, 2018: Photodermatology, Photoimmunology & Photomedicine
Lok Chin Wong, Adawiyah Jamil, Norazirah Md Nor
BACKGROUND: Ethnicity, skin phototype and colour influenced minimal erythema dose (MED). Sun exposure has been postulated to increase MED. We determined immediate pigment darkening dose to UVA (IPDDA), MED and minimal melanogenic dose (MMD) for UVB and UVA, and investigated factors affecting these doses. METHODS: Skin phototype was determined using Fitzpatrick phototype quiz, DSMII ColorMeter measured skin colours, sun exposure quantified using an index (SEI) and phototest performed with MEDlight-Multitester...
June 28, 2018: Photodermatology, Photoimmunology & Photomedicine
Therdpong Tempark, Suparuj Lueangarun, Susheera Chatproedprai, Ratchathorn Panchaprateep, Marisa Pongprutthipan, Siriwan Wananukul
BACKGROUND: Limited data of sun protection knowledge in laser treatment patients exists therefore, preventative information should be provided by dermatologists to minimize harmful effects. OBJECTIVE: To assess sun protection knowledge-behavior and knowledge to prevent adverse events from laser therapy among patients who visited a laser clinic at a tertiary university hospital in Bangkok, Thailand. METHODS: This is a self-reported questionnaire, cross-sectional survey...
June 22, 2018: Photodermatology, Photoimmunology & Photomedicine
Ho-Jin Kim, Ki-Ho Kim
BACKGROUND: Chronic actinic dermatitis (CAD) develops in seasons where there is high sun exposure, such as summer, and can persistent throughout the year in severely affected cases. The authors noted that CAD prevalence increased in relation to climate changes and air pollutants. METHODS: We retrospectively analyzed 294 patients with newly diagnosed CAD between December 2000 and November 2016. We investigated the annual trend of sun hours, humidity, and ground-level ozone and respirable particles (PM10) in Pusan, Korea; correlations between climate change and/or air pollution and the incidence of patient with CAD were analyzed...
June 11, 2018: Photodermatology, Photoimmunology & Photomedicine
Alesia M Jung, Leslie K Dennis, Elizabeth T Jacobs, Georg T Wondrak
BACKGROUND/PURPOSE: Sun sensitivity, a confounder between sun exposure and sun protection, is often overlooked. We examined how sun exposure and sun protection behaviors among indoor workers varied by sun sensitivity. METHODS: Sun exposure and sun protection diaries over a 45-day period from Midwestern United States indoor workers were examined. We categorized sun sensitivity (fair and non-fair complexion) using tanning inability and sunburn tendency. Total exposure (sunrise to sunset) and peak exposure (10 am and 4 pm) lasting at least 60 minutes were examined...
June 11, 2018: Photodermatology, Photoimmunology & Photomedicine
Giedre Bieliauskiene, Peter A Philipsen, Hans Christian Wulf
BACKGROUND/PURPOSE: Skin phototype questionnaires usually ask similar questions, but they differ in how the answers can be given. There is either one combined answer, which includes both tendency to burn and ability to tan, or 2 separate answers about burn and tan, respectively. We tested the reproducibility of different questionnaires and their relation to objectively measured skin phototype. METHOD: A total of 149 participants completed 3 skin phototype questionnaires distributed twice with median 3 months interval: (i) a Fitzpatrick questionnaire (FST-q) with combined answers about tendency to burn and ability to tan, (ii) a detailed questionnaire (Detail-q) with separate answers to 2 detailed questions about burn and tan and (iii) a short questionnaire (Short-q) with separate answers to 2 simplified questions about burn and tan...
June 8, 2018: Photodermatology, Photoimmunology & Photomedicine
Nahla Shihab, Henry W Lim
The increased use of ultraviolet (UV) nail lamps in recent years has generated safety concerns of this device. A UV nail lamp is a source of artificial UVA radiation, often used to dry, harden, and cure the nails at home and in the salon. UVA radiation is known to be mutagenic and can cause damage to the DNA, resulting in cutaneous malignancy. Currently, there are only a few studies that have evaluated UV nail lamp irradiation and its potential carcinogenic risk. We review the literature on UV nail lamps, its safety, effect on nails and hands, and the potential role in increasing the risk of cutaneous malignancy...
June 8, 2018: Photodermatology, Photoimmunology & Photomedicine
Bistra I Veleva, Rutger L van Bezooijen, Victor G M Chel, Mattijs E Numans, Monique A A Caljouw
BACKGROUND: Human and animal studies have shown that exposure to ultraviolet light can incite a chain of endocrine, immunologic, and neurohumoral reactions that might affect mood. This review focuses on the evidence from clinical trials and observational studies on the effect of ultraviolet light on mood, depressive disorders, and well-being. METHODS: A search was made in PubMed, Embase, Web of Science, Cochrane, Psychinfo, CINAHL, Academic Search Premier and Science Direct, and the references of key papers, for clinical trials and observational studies describing the effect of ultraviolet light applied to skin or eyes on mood, depressive disorders, and well-being...
June 1, 2018: Photodermatology, Photoimmunology & Photomedicine
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