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Photodermatology, Photoimmunology & Photomedicine

Juan Pablo Castanedo-Cázares, Juan Diego Cortés-García, Cornelia Fuentes-Ahumada, Karla Martinez-Rosales, Bertha Torres-Álvarez
BACKGROUND/PURPOSE: Vitiligo is the most commonly acquired depigmentation disorder of the skin and is characterized by the destruction of melanocytes. Ultraviolet phototherapy with narrow band (UVB-NB) induces proliferation, differentiation, maturation, and migration of melanocytes. The clinical repigmentation is featured by follicular, marginal, and diffuse patterns. The aim of this study was to observe the process involved in the melanocyte migration and proliferation among these patterns and the unresponsive lesions following UVB-NB phototherapy...
October 5, 2016: Photodermatology, Photoimmunology & Photomedicine
Shoko Tajima, Atsushi Fukunaga, Chikako Nishigori
No abstract text is available yet for this article.
October 5, 2016: Photodermatology, Photoimmunology & Photomedicine
Ronghua Li, Meng Qiao, Xiaoyan Wang, Xintong Zhao, Qing Sun
BACKGROUND: The treatment of vitiligo is still one of the most difficult dermatological challenges, although there are many therapeutic options. Narrow band ultraviolet B (NB-UVB) phototherapy is considered to be a very important modality for generalized vitiligo. OBJECTIVE: The aim of this study was to explore whether a combination of NB-UVB and topical agents would be superior to NB-UVB alone for treating vitiligo. METHODS: We searched the electronic databases such as PUBMED, EMBASE, Cochrane Library and Web of Science...
October 1, 2016: Photodermatology, Photoimmunology & Photomedicine
Chang Taek Oh, Tae-Rin Kwon, Eun Ja Choi, Soon Re Kim, Joon Seok, Seog Kyun Mun, Kwang Ho Yoo, Yeon Shik Choi, Sun Young Choi, Beom Joon Kim
BACKGROUND: Skin hyperpigmentary disorders including postinflammatory hyperpigmentation, melasma, solar lentigines, and conditions like freckles are common. The light-emitting diodes (LEDs) are the latest category of nonthermal and noninvasive phototherapy to be considered in skin pigmentation disorder treatment. PURPOSE: The purpose of this study was to investigate the effects of 660-nm LED on inhibition of melanogenesis. We investigated whether a 660-nm LED affected melanin synthesis in in vitro and in vivo models, and we explored the mechanisms involved...
October 1, 2016: Photodermatology, Photoimmunology & Photomedicine
Beata Mianowska, Joanna Narbutt, Antony Richard Young, Wojciech Fendler, Beata Małachowska, Wojciech Młynarski, Aleksandra Lesiak
BACKGROUND: Seasonal variation in glycated hemoglobin levels has been observed, and sun exposure has been considered as one of the factors associated with this relationship. Fructosamine is a short-time marker of blood protein glycation. AIM: We investigated the effect of seven days of sunbathing on blood fructosamine concentration in healthy volunteers using different ultraviolet radiation (UVR) protections. MATERIALS AND METHODS: Participants were assigned to one of three groups: group A - used a UVA and UVB absorbing sunscreen (N = 15), group B - used a UVB absorbing sunscreen (N = 18), and group C - followed uncontrolled sun protection habits (N = 22)...
September 13, 2016: Photodermatology, Photoimmunology & Photomedicine
Juliette M Hardy, Marie-Claude Marguery, Anne Huynh, Cécile Borel, Pol André Apoil, Laurence Lamant, Emilie Tournier, Chloé Alberto, Céline Pauwels, Marianne Thomas, Juliette Mazereeuw Hautier, Carle Paul, Cristina Bulai Livideanu
Overlap chronic graft-versus-host disease (GVHD) associates both features of acute and chronic GVHD. Trigger factors for chronic GVHD are unclear. We describe two patients who received allogenic haematopoietic stem-cell transplantation, and who later developed overlap chronic GVHD after sun exposure. Available data from in vivo investigations suggest ultraviolet B radiation (UVB) has a beneficial effect on acute and chronic GVHD. The role of sun irradiation as a trigger for isomorphic cutaneous GVHD has been rarely reported in the literature...
September 13, 2016: Photodermatology, Photoimmunology & Photomedicine
Tugba Kevser Uzuncakmak, Ayse Serap Karadag, Emin Ozlu, Necmettin Akdeniz, Bengu Cobanoglu Simsek
No abstract text is available yet for this article.
September 13, 2016: Photodermatology, Photoimmunology & Photomedicine
Marie Moncourier, Safaë Assikar, Ioana Matei, Nicole Souyri, Marion Couture, Emilie Rigot, Stéphanie Delauménie, Christophe Bédane
Solar urticaria (SU) is a rare type of physical urticaria triggered by sun exposure with pathognomonic wheal and flare seen within five to ten minutes of sun exposure. The mechanism of action is a type 1 hypersensibility, Immunoglobulin E mediated, triggered by an unknown photoallergen. Phototesting determines the eliciting action spectrum and the minimal urticaria dose. The first line treatment relay on antihistamines and sun protectors. Other treatment options are phototherapy, plasmapheresis, cyclosporin A, and intravenous immunoglobulin (1)...
September 13, 2016: Photodermatology, Photoimmunology & Photomedicine
María Victoria de Gálvez, José Aguilera, Cristina Sánchez-Roldán, Enrique Herrera-Ceballos
BACKGROUND: Photodermatoses are typically investigated by analyzing the individual or combined effects of ultraviolet A (UVA), ultraviolet B (UVB), and visible light using light sources that simulate portions of the solar spectrum. Infrared radiation (IRR), however, accounts for 40% of incident solar radiation, but its effects are not taken into account in standard phototest protocols. AIMS: To analyze the effects of IRR, alone and combined with UVA and visible light on solar urticaria lesions, with a distinction between infrared A (IRA) and infrared B (IRB)...
September 13, 2016: Photodermatology, Photoimmunology & Photomedicine
Lorena Barboza-Guadagnini, Julio Bassas-Vila, José Aguilera, Carlos Ferrándiz, José-Manuel Carrascosa
No abstract text is available yet for this article.
August 23, 2016: Photodermatology, Photoimmunology & Photomedicine
Ewan Eadie, Ronan M Valentine, Grace Thompson, Kevin Campbell, Harry Moseley
No abstract text is available yet for this article.
August 23, 2016: Photodermatology, Photoimmunology & Photomedicine
Funda Bapur Erduran, Esra Adışen
BACKGROUND: In recent years, excimer light treatments have come to the fore in localized vitiligo because of their high efficacy and safety. OBJECTIVE: We aimed to evaluate the efficacy of 308-nm excimer lamp as a monotherapy and its combination with tacrolimus 0.1% or clobetasol 17-propionate 0.05% ointment in localized vitiligo. METHODS: We performed a retrospective study including a total of 82 patients who were treated with excimer lamp monotherapy (EL group) (n = 30), excimer lamp + topical tacrolimus (EL + T group) (n = 29), or excimer lamp + topical clobetasol 17-propionate (EL + CS group) (n = 23)...
August 23, 2016: Photodermatology, Photoimmunology & Photomedicine
Priyadarshini Sahu, Vijay Kumar Jain, Kamal Aggarwal, Sarabjit Kaur, Surabhi Dayal
BACKGROUND: Phototherapy especially narrow-band UV-B (NBUVB) has been considered as mainstay of therapy in nonsegmental vitiligo (generalized type). Topical tacalcitol has also been claimed to be effective, either as monotherapy or as combination therapy. PURPOSE: Comparison of clinical efficacy and safety of NBUVB in combination with topical tacalcitol vs. NBUVB alone in vitiligo. MATERIAL & METHODS: Thirty patients with symmetrical vitiliginous lesions were enrolled for 24 weeks...
August 23, 2016: Photodermatology, Photoimmunology & Photomedicine
Christina M Ring, Matthew Keller
In recent years, the media has paid increasing attention to the safety and efficacy of sunscreens, generating confusion and fear in the general public and prompting comments from the American Academy of Dermatology and Skin Cancer Foundation. A prominent non-profit organization has made public claims that sunscreens are toxic, can alter hormone levels and cause birth defects and cancer, which have been perpetuated by the media. To ascertain the impact of these media claims on public opinion, we conducted a survey of 109 patients in a general dermatology clinic...
July 14, 2016: Photodermatology, Photoimmunology & Photomedicine
Helen Cordey, Sally Ibbotson
Topical photodynamic therapy (PDT) is a well-established treatment for actinic keratosis, Bowen's disease and superficial basal cell carcinoma and its use has also been explored for a variety of other indications.(1,2,3) Treatment involves application of a pro-drug (either 5-aminolaevulinic acid (ALA) or its methlyester, methylaminolevulinate (MAL)) which is preferentially taken up by dysplastic or neoplastic cells and converted into the active photosensitiser protoporphyrin IX (PPIX). Subsequent activation of PPIX by red light results in the production of cytotoxic oxygen species, inflammation and relatively selective diseased tissue destruction...
July 7, 2016: Photodermatology, Photoimmunology & Photomedicine
S Schubert, P Rieper, A Ohlenbusch, C Seebode, J Lehmann, A Gratchev, S Emmert
BACKGROUND: The nucleotide excision repair (NER) pathway, defective in xeroderma pigmentosum (XP) patients, removes DNA photolesions in order to prevent carcinogenesis. Complementation group C (XP-C) is the most frequent group of XP patients worldwide. METHODS: We analyzed seven XP-C patients clinically and molecular-genetically applying: post-UV cell survival (MTT-assay), quantitative Real-time PCR, sequencing on chromosomal as well as cDNA level, and in silico interpretation of sequencing data...
July 7, 2016: Photodermatology, Photoimmunology & Photomedicine
Avraham Kudish, Anna Marsakova, Irmgard Jahn, Spyridon Gkalpakiotis, Peter Arenberger, Marco Harari
BACKGROUND: Atopic Dermatitis (AD) is a common, chronic and relapsing inflammatory skin disorder. Moderate to severe cases represent an extremely disabling disease, for both children and their parents. Dead Sea Climatotherapy (DSC), recognized as a natural treatment for patients with skin diseases, takes advantage of the selectively scattered ultraviolet irradiation (UV) present at the lowest terrestrial site on the earth. OBJECTIVES: To investigate the impact on short-term results of DSC in moderate to severe AD children from the Czech Republic treated 4 weeks at the Deutsches Medizinisches Zentrum (DMZ), Israel and to correlate their results to the cumulative UVA and UVB irradiation doses received during treatment...
July 5, 2016: Photodermatology, Photoimmunology & Photomedicine
(no author information available yet)
No abstract text is available yet for this article.
July 2016: Photodermatology, Photoimmunology & Photomedicine
Lilla Landeck, Ivone Jakasa, Irena Dapic, René Lutter, Jacob P Thyssen, Lone Skov, Andrea Braun, Michael P Schön, Swen M John, Sanja Kezic, Richard Brans
BACKGROUND/PURPOSE: Urocanic acid (UCA) absorbs ultraviolet (UV)B radiation in the epidermis which may interfere with phototherapy. Therefore, the influence of individual levels of UCA on immune reactivity and vitamin D synthesis induced by narrowband UVB radiation was assessed. METHODS: Twenty-eight subjects with irritant contact dermatitis of the hands were irradiated with suberythemal doses of narrowband UVB radiation on their unaffected lower forearms on three consecutive days...
July 2016: Photodermatology, Photoimmunology & Photomedicine
Mike Climstein, James Furness, Wayne Hing, Joe Walsh
BACKGROUND/PURPOSE: Surfing is one of the most popular outdoor aquatic activities in Australia with an estimated 2.7 million recreational surfers; however, Australia has long been recognized as having the highest incidence of melanoma in the world, and it is the most common type of cancer in young Australians. The aim of this study was to investigate the lifetime prevalence of non-melanoma [basal cell carcinoma (BCC), squamous cell carcinoma (SCC)] and melanoma skin cancers in Australian recreational and competitive surfers...
July 2016: Photodermatology, Photoimmunology & Photomedicine
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