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Nick Morrison, Raghu Kolluri, Michael Vasquez, Monte Madsen, Andrew Jones, Kathleen Gibson
OBJECTIVE: To evaluate the 36-month efficacy and safety of cyanoacrylate closure for the treatment of incompetent great saphenous veins in comparison with radiofrequency ablation. METHODS: In this multicenter, prospective, randomized controlled trial, 222 symptomatic subjects with incompetent great saphenous veins were assigned to either cyanoacrylate closure or radiofrequency ablation. The primary endpoint, complete closure of the target great saphenous vein, was determined using duplex ultrasound examination starting from three-month visit...
November 7, 2018: Phlebology
Evangelos Dimakakos, Konstantinos Livanios, Ioannis Gkiozos, Adriani Harpidou, Eleutheria Ntalakou, Llias Kainis, Konstantinos Syrigos
No abstract text is available yet for this article.
November 7, 2018: Phlebology
Mark S Whiteley, Emma B Dabbs, Eluned L Davis, Previn Diwakar
No abstract text is available yet for this article.
November 4, 2018: Phlebology
Paul K Thibault
BACKGROUND: The objective of this review is to describe the diagnosis of neck vein obstruction and the possible role of chronic persistent Chlamydophila pneumoniae infection in producing the syndrome of chronic cerebrospinal venous obstruction. METHOD: The normal patterns of flow in the neck veins are described and guidelines for interpretation of the quantitative duplex ultrasound examination of the extracranial neck veins are developed. RESULT: An infective cause of neck vein obstruction is proposed and from a literature search of the role of the obligate intracellular bacterium Chlamydophila pneumoniae in vascular and chronic diseases, a diagnostic protocol for confirming chronic persistent Chlamydophila pneumoniae infection, which includes the quantitative duplex ultrasound examination and specific blood tests are suggested...
October 25, 2018: Phlebology
Benjamin J Langridge, Richard J Goodall, Sarah Onida, Joseph Shalhoub, Alun H Davies
No abstract text is available yet for this article.
October 25, 2018: Phlebology
Paolo Zamboni, Alessia Giaquinta, Erika Rimondi, Massimo Pedriali, Eugenio Scanziani, Pietro Riccaboni, Massimiliano Veroux, Paola Secchiero, Pierfrancesco Veroux
Objective To investigate the biological effects of a novel endovenous scaffold in a porcine model. Methods Petalo is a compliant venous scaffold implanted into the internal jugular veins of 12 healthy pigs. The pigs were sacrificed at one, two, three, and six months, respectively. Microscopic investigations were performed at two blinded laboratories. Results Neo-intima formation progressively covering up the stent metallic bars was observed. The inflammatory response of the venous wall showed a peak after three months by the implant, followed by marked reduction after six months...
October 18, 2018: Phlebology
Kenneth Myers
Introduction The syringe has become an indispensable instrument for many aspects of interventional medicine and everyday practice. Methods To trace the evolution of the syringe from ancient times to the present, using the internet for past documentation and the literature. Conclusion The syringe has long been used for aspiration, irrigation and infusion. This developed into injections for early transfusion, anaesthesia and surgical procedures including venous sclerotherapy. Syringes have been adapted for use to inject specific drugs...
October 18, 2018: Phlebology
Murat Sargin, Muge Mete Tasdemir, Huseyin Kuplay, Sevinc Bayer Erdogan, Nehir Tandogar, Serdar Akansel, Erol Kurc, Gokcen Orhan, Serap Aykut Aka
Objective To evaluate the international normalized ratio (INR) monitoring patterns in patients with deep vein thrombosis. Methods Of 32,012 patients with ≥1 outpatient INR measurement and 42,582 patients with confirmed deep vein thrombosis diagnosis registered to our hospital between 1 January 2010 and 31 December 2013, 6720 records were identified to have both deep vein thrombosis and international normalized ratio measurement, and 4.377 out of 6.720 single patient records were determined to be statistically analyzable...
October 18, 2018: Phlebology
Saima Ahmad, Fahd Kamal Akhtar
Purpose To present a case series of percutaneous sclerotherapy of para-orbital and orbital venous malformations. Method Seven patients with venous malformations in the orbital and para-orbital region were reviewed. Puncture venogram was performed on all patients and image guided bleomycin injections using biplane digital subtraction in angiography suite. Results Average age of patients at the time of the procedure was 22 years old with the youngest being five years of age and the oldest being 50 years. Follow-ups ranged from 3 months to 18 months and the average follow-up duration was 13 months...
October 18, 2018: Phlebology
Garrett Easson, Megan Laughlin, Hanna Jensen, Kevin Haney, Marc Girardot, Morten Jensen
Objectives The purpose of this study is to test venous valve performance and identify differences between native tissue and replacement devices developed with traditional tissue treatment methods using a new in vitro model with synchronized hemodynamic parameters and high-speed valve image acquisition. Methods An in vitro model mimicking the venous circulation to test valve performance was developed using hydrostatic pressure driven flow. Fresh and glutaraldehyde-treated vein segments were placed in the setup and opening/closing of the valves was captured by a high-speed camera...
October 18, 2018: Phlebology
Kenneth Myers
Introduction Sclerotherapy in all its current forms is based on experience going back to the 1850s. Methods To trace the evolution of sclerotherapy over the past 250 years, using the internet for past documentation and the literature. Conclusion Sclerotherapy principles were established long ago, although current modifications have been made possible by the introduction of detergent sclerosants and ultrasound guidance.
October 18, 2018: Phlebology
Huw Ob Davies, Matthew Popplewell, Gareth Bate, Ronan P Ryan, Tom P Marshall, Andrew W Bradbury
Background NICE Clinical Guidelines (CG) 168, published in July 2013, recommend specialist vascular referral for all leg ulcers, defined as a break in the skin below the knee that has not healed within two weeks. Aim To examine the impact of CG168 on the primary care management of leg ulcers using The Health Improvement Network database. Methods An eligible population of approximately two million adult patients was analysed over two 18-month periods before and after publication of CG168. Those with a new diagnosis of leg ulcers in each time period were analysed in terms of demographics, specialist referral and superficial venous ablation...
October 18, 2018: Phlebology
Pulkit Rastogi, Narender Kumar, Jasmina Ahluwalia, Reena Das, Neelam Varma, Vikas Suri, Harikishan Senee
Introduction Deep vein thrombosis is a multifactorial disease with many acquired and genetic risk factors. Polymorphism in the APOE gene is an upcoming potential pathogenic factor whose role is unclear in deep vein thrombosis. Methods An equal number of deep vein thrombosis cases and controls (N = 100, each) were investigated for APOE gene polymorphisms along with known acquired and hereditable thrombophilic risk factors. APOE genotyping was done by polymerase chain reaction. Results The ε3/ε4 and ε2/ε3 APOE genotypes were commoner in deep vein thrombosis cases than controls but not statistically significant ( ε3/ε4 → 18% versus 11%, OR = 1...
October 3, 2018: Phlebology
Kathleen Gibson, Renee Minjarez, Krissa Gunderson, Brian Ferris
Purpose Studies examining cyanoacrylate closure of saphenous veins with the VenaSeal™ System have not allowed concomitant procedures for tributaries at the time of the index procedure. Outside of clinical trials, however, concomitant procedures are frequently performed in conjunction with endovenous ablation. We report on the frequency of need for saphenous tributary treatment three months after cyanoacrylate closure of the treatment of great saphenous vein, small saphenous vein, and/or accessory saphenous vein...
September 18, 2018: Phlebology
Isaac K Nyamekye
Background Thermal ablation, usually performed with tumescent local anaesthesia (TLA), is the preferred method for varicose veins treatment. Tumescent local anaesthesia is always cited; however, little detail of the procedure is presented in publications. This retrospective audit of clinical tumescent local anaesthesia practice aims to provide detailed information on an important aspect of endovenous practice. Methods Patients who underwent three types of endothermal treatment (Venefit, Radiofrequency Induce Thermal Therapy and Endovenous Laser Ablation) to a single saphenous trunk using tumescent local anaesthesia were assessed...
September 18, 2018: Phlebology
Haijie Che, Jingjun Jiang, Hao Liu, Jichang Wei, Xiaoming Zhang
Background Iliofemoral vein stenosis or occlusion is a common cause of severe chronic venous insufficiency. Endovascular venous stenting has become a preferred treatment because it is minimally invasive and has a high safety profile. Despite the wide application of the wallstent, it is not specifically designed for veins. There are currently few studies on braided stents in the field of veins. We designed a novel braided vein stent, which has higher radial resistive force and more optimized looped ends structure compared with the wallstent...
September 18, 2018: Phlebology
Paul Thibault
No abstract text is available yet for this article.
September 14, 2018: Phlebology
Omar Rodriguez-Acevedo, Kristen E Elstner, Kui Martinic, Rn Isabelle Ibrahim, Rodrigo Tomazini Martins, Fernando Arduini, Nabeel Ibrahim
Background Recurrence rates and patterns after endovenous radiofrequency ablation (ERFA) are poorly documented. Objective To assess the incidence and anatomical recurrence patterns of saphenous vein reflux after ERFA. Method Two hundred patients previously treated with ERFA were recalled for clinical assessment and venous-duplex ultrasound at three years post-treatment. Results A total of 106 patients (68F, 38M) with a mean age of 49.4 years (SD +11.5y) were assessed. Mean follow-up was 42.1 months (SD + 20...
September 12, 2018: Phlebology
Alastair Lewis
No abstract text is available yet for this article.
September 10, 2018: Phlebology
Álvaro Ayala, Jose D Guerra, Jorge H Ulloa, Lowell Kabnick
Objectives To describe compliance rates of compression therapy in a cohort of patients with chronic venous disease and also to describe frequent causes of non-compliance. Methods A total of 889 patients with primary chronic venous disease were prescribed compression therapy after being evaluated by vascular surgeons. Subjects had a first visit during which time compression therapy was prescribed in addition to a follow-up visit. Strength of compression, type, prescription duration, and reasons of non-compliance were queried at follow-up...
September 6, 2018: Phlebology
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