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Phlebology

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https://www.readbyqxmd.com/read/28166694/novel-developments-in-foam-sclerotherapy-focus-on-varithena%C3%A2-polidocanol-endovenous-microfoam-in-the-management-of-varicose-veins
#1
Phoebe Star, David E Connor, Kurosh Parsi
Scope Varithena® is a recently approved commercially available drug/delivery unit that produces foam using 1% polidocanol for the management of varicose veins. The purpose of this review is to examine the benefits of foam sclerotherapy, features of the ideal foam sclerosant and the strengths and limitations of Varithena® in the context of current foam sclerotherapy practices. Method Electronic databases including PubMed, Medline (Ovid) SP as well as trial registries and product information sheets were searched using the keywords, 'Varithena', 'Varisolve', 'polidocanol endovenous microfoam', 'polidocanol' and/or 'foam sclerotherapy/sclerosant'...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28164739/corrigendum
#2
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28134021/endovenous-laser-treatment-of-groin-and-popliteal-varicose-veins-recurrence
#3
Alvise Cavallini, Daniela Marcer, Salvatore Ferrari Ruffino
Objectives Recurrent varicose veins following surgery is a common, complex and costly problem in vascular surgery. Treatment for RVV is technically more difficult to perform and patient satisfaction is poorer than after primary interventions. Nevertheless, traditional vein surgery has largely been replaced by percutaneous office-based procedures, and the patients with recurrent varicose veins have not benefited from the same advantages. In this paper, we propose an endovascular laser treatment that allows reducing the invasiveness and complications in case of SFJ and SPJ reflux after ligation and stripping of the great and small saphenous vein...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28134020/femoral-vein-valve-incompetence-as-a-risk-factor-for-junctional-recurrence
#4
Sergio Gianesini, Savino Occhionorelli, Erica Menegatti, Anna Maria Malagoni, Mirko Tessari, Paolo Zamboni
Background Recurrent varicose veins occur up to 80% of procedures. The sapheno-femoral junction can be involved in more than 50% of cases. A detailed pathophysiological explanation of the phenomenon is still missing. The aim of the present work is to evaluate the role of femoral vein incompetence as risk factor for sapheno-femoral junction recurrence. Methods Three-hundred-eighty-one patients presenting an incompetent great saphenous vein system and eventually also an incompetent femoral tract (C2-6EpAsdPr) underwent a great saphenous vein high ligation with flush ligation also of the incompetent tributaries along the leg, sparing the saphenous trunk...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28134019/superficial-vein-thrombosis-in-non-varicose-veins-of-the-lower-limbs-and-thrombophilia
#5
Gabriella Lucchi, Salvino Bilancini, Sandro Tucci, Massimo Lucchi
Objectives Superficial vein thrombosis in non-varicose veins of the lower limbs is rather frequent and may be underestimated. This study aims to evaluate the prevalence of inherited or acquired thrombophilia in a sample of outpatients with the disease. Method An observational study was conducted on 73 consecutive superficial vein thrombosis patients tested for inherited or acquired thrombophilia. Results Sixty of 73 patients with superficial vein thrombosis completed the testing protocol, while 13 dropped out; 46 of 60 patients were found to have a thrombophilia (76...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28121229/post-thrombotic-syndrome-following-deep-vein-thrombosis-in-paediatric-patients
#6
Klara Vosicka, Mahim I Qureshi, Susan E Shapiro, Chung S Lim, Alun H Davies
Background Although well characterised in adults, less is known about post-thrombotic syndrome in children. In this review, current knowledge regarding paediatric post-thrombotic syndrome is summarised, with particular emphasis on pathophysiology, aetiology, diagnosis and management. Methods A Medline literature review was performed using search terms 'post thrombotic syndrome', 'post phlebitic syndrome', paediatric and children. Relevant articles were identified and included for summation analysis. Results The incident of paediatric venous thromboembolism is rising...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28114848/improvement-in-patient-reported-outcomes-of-varicose-veins-following-treatment-with-polidocanol-endovenous-microfoam
#7
Brajesh K Lal, Rajiv Mallick, David Wright
Objective To evaluate the relationship between patient-reported symptoms and functional and psychological impact of varicose veins following treatment with polidocanol endovenous microfoam (PEM) 1%. Methods Data were pooled from two randomized trials on VV treatment. Wilson-Cleary health outcomes path model was applied to evaluate impact of VVSymQ® symptom score improvement on modified VEINES-QOL/Sym functional and psychological scores. Change scores were evaluated for (i) PEM 1% versus placebo groups and (ii) quartiles of symptom improvement...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28094663/high-pressure-low-flow-remodeling-of-the-rat-saphenous-vein-wall
#8
Judit R Hetthéssy, Anna-Mária Tőkés, Sándor Kérész, Petra Balla, Gabriella Dörnyei, Emil Monos, György L Nádasy
Objective To better understand factors that may play a role in the development of varicosities. Methods We induced combined flow-pressure disturbance in the saphenous system of the rat by performing chronic partial clipping of the main branch. Biomechanical and quantitative histological testing was undertaken. Results A rich microvenous network developed. Bloodflow decreased to 0.65 ± 0.18 µl/s (control side, 3.5 ± 1.4 µl/s) and pressure elevated to 6.8 ± 0.7 mmHg (control side, 2.3 ± 0...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28092206/impact-of-uk-nice-clinical-guidelines-168-on-referrals-to-a-specialist-academic-leg-ulcer-service
#9
Huw Ob Davies, Matthew Popplewell, Gareth Bate, Lisa Kelly, Katy Darvall, Andrew W Bradbury
Background Leg ulcers are a common cause of morbidity and disability and result in significant health and social care expenditure. The UK National Institute for Health and Care Excellence (NICE) Clinical Guideline (CG)168, published in July 2013, sought to improve care of patients with leg ulcers, recommending that patients with a break in the skin below the knee that had not healed within two weeks be referred to a specialist vascular service for diagnosis and management. Aim Determine the impact of CG168 on referrals to a leg ulcer service...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28092205/effect-of-polidocanol-foam-administration-into-rat-peripheral-veins-on-pulmonary-parenchyma
#10
Melissa A de Moraes Silva, Rimarcs G Ferreira, Seleno G de Jesus-Silva, Rodolfo S Cardoso, Fausto Miranda
Background Sclerotherapy has been gaining increased acceptance and popularity as an effective therapy for the treatment of varicose veins. This attention has fed growing interest into the safety and potential complications of this procedure. There is no evidence of pulmonary complications from foam sclerotherapy in humans; however, animal studies have shown possible damage. The aim of this study is to show the changes in rat pulmonary parenchyma after the injection of 1% polidocanol Tessari foam into the peripheral vein using histological analysis of the inflammatory and fibrosis processes...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28084901/lower-limbs-venous-kinetics-and-consequent-impact-on-drainage-direction
#11
Sergio Gianesini, Francesco Sisini, Giovanni Di Domenico, Joel Secchiero, Anna Maria Malagoni, Erica Menegatti, Mauro Gambaccini, Paolo Zamboni
Background Literature concerning the lower limbs physiological venous haemodynamics is still lacking of reference velocity values and consequent impact on drainage direction. Aim of the present study is to assess the flow velocities in the different venous compartments, evaluating the possible Venturi effect role, thus finding clues for the identification of the physical model governing the flow direction. Methods Thirty-six lower limbs underwent a velocity and diameters echo-color-Doppler assessment in several anatomical point of analysis along both the deep and superficial venous systems...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28081661/patients-and-physicians-agree-only-partially-in-symptoms-and-clinical-findings-before-and-after-treatment-for-varicose-veins
#12
Lotte Klitfod, Henrik Sillesen, Leif Panduro Jensen
Objective Quality improvement in surgery has mainly been based on clinical database outcomes. This study compared variables from the patient-reported Aberdeen Varicose Vein Questionnaire with the Danish Clinical Vein Database, in order to reveal agreements and differences in symptoms and clinical findings. Methods In the period January-March 2011, 379 legs in 287 patients treated for varicose veins were registered in the Danish Clinical Vein Database and compared to the Aberdeen Varicose Vein Questionnaire...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28081660/valsalva-maneuver-in-phlebologic-practice
#13
Stefano Ricci, Leo Moro, Girolamo C Minotti, Raffaele A Incalzi, Marianne De Maeseneer
Forced expiration against an airway obstruction was originally described as a method for inflating the Eustachian tubes and is accredited to Antonio Maria Valsalva (1666-1723). The Valsalva maneuver is commonly applied for different diagnostic purposes. Its use for phlebologic diagnosis is the object this review. Venous reflux is the most frequent pathophysiologic mechanism in chronic venous disease. Reflux is easily visualized by duplex ultrasound when properly elicited, in standing position. A simple way to elicit reflux is the so-called "compression-release maneuver": by emptying the muscle reservoir, it determines a centrifugal gradient, dependent on hydrostatic pressure, creating an aspiration system from the superficial to the deep system...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28077026/a-case-control-study-of-risk-factors-of-chronic-venous-ulceration-in-patients-with-varicose-veins
#14
Gohar Abelyan, Lusine Abrahamyan, Gayane Yenokyan
Background/objectives Venous ulcers carry psychological and high financial burden for patients, causing depression, pain, and limitation of mobility. The study aimed to identify factors associated with an increased risk of venous ulceration in patients with varicose veins in Armenia. Methods A case-control study design was utilized enrolling 80 patients in each group, who underwent varicose treatment surgery in two specialized surgical centers in Armenia during 2013-2014 years. Cases were patients with varicose veins and venous leg ulcers...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28073316/clinical-implications-of-the-anatomical-variation-of-deep-venous-thrombosis
#15
Ayman El-Menyar, Mohammad Asim, Gaby Jabbour, Hassan Al-Thani
Introduction Little is known about the anatomic variation and its implication in patients with lower limb deep venous thrombosis (DVT). We studied the clinical presentation, site of thrombosis and risk factors based on the anatomic distribution of lower limb DVT. Methods A retrospective analysis of clinically suspected DVT cases was conducted between 2008 and 2012. DVT was categorized by the location of the thrombosed segment and limb involved. The DVT anatomic segments were assessed according to left-to-right ratio, predisposing factors and clinical presentations...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28056702/management-of-venous-ulcers-according-to-their-anatomical-relationship-with-varicose-veins
#16
Yun-Nan Lin, Tung-Ying Hsieh, Shu-Hung Huang, Chia-Ming Liu, Kao-Ping Chang, Sin-Daw Lin
Background Adequately excising varicose and incompetent perforating veins is necessary for reducing their recurrence rate of venous ulcer. Method In total, 66 venous ulcers (C6) in 1083 legs with primary varicose veins were managed through endoscopic-assisted surgery. In an endoscopic operative view, the nonvaricose, varicose, and incompetent perforating veins were clearly visualized and precisely dissected. The varicose and incompetent perforating veins were divided and completely excised. Result The varicose veins were traced to the base or periphery of the 55 ulcers...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28056701/rivaroxaban-vs-warfarin-on-extended-deep-venous-thromboembolism-treatment-a-cost-analysis
#17
Adem I Diken, Adnan Yalçınkaya, Muhammet O Hanedan, Mehmet E Erol, Özlem Ercen Diken
Background Standard treatment for deep venous thromboembolism involves parenteral anticoagulation overlapping with a vitamin K antagonist, an approach that is effective but associated with limitations including the need for frequent coagulation monitoring. The direct oral anticoagulant rivaroxaban is similarly effective to standard therapy as a single-drug treatment for venous thromboembolism and does not require routine coagulation monitoring. The aim of this analysis was to project the long-term costs and outcomes for rivaroxaban compared to standard of care (tinzaparin/warfarin)...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28056700/the-current-status-of-air-plethysmography-in-evaluating-non-thrombotic-iliac-vein-lesions
#18
Christopher R Lattimer, Erika Mendoza, Evi Kalodiki
No abstract text is available yet for this article.
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28056699/functional-chronic-venous-disease-a-systematic-review
#19
Raffaele Serra, Michele Andreucci, Giovanni De Caridi, Mafalda Massara, Pasquale Mastroroberto, Stefano de Franciscis
Objectives Functional chronic venous disease is an underestimated syndrome quite present in the general population. It affects up to 20% of the general population and is based on the presence of venous symptoms without instrumental evidence of anatomic and morphologic damage. The aim of this review article is to provide the reader with the most updated information on this phenomenon. Methods Medline and Scopus databases were searched without time limit using the key-word: 'Functional chronic venous disease of legs', C0s patients...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28056698/effective-anti-dvt-prophylaxis-in-patients-undergoing-endovenous-treatment-of-varicose-veins
#20
Isaac K Nyamekye
No abstract text is available yet for this article.
January 1, 2017: Phlebology
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