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Coronary Artery Disease

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https://www.readbyqxmd.com/read/29140809/stem-cell-therapy-for-acute-myocardial-infarction-on-the-horizon-or-still-a-dream
#1
Kenneth M Fish, Kiyotake Ishikawa, Roger J Hajjar
No abstract text is available yet for this article.
November 14, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29140808/randomized-trial-evaluating-the-effect-of-aged-garlic-extract-with-supplements-versus-placebo-on-adipose-tissue-surrogates-for-coronary-atherosclerosis-progression
#2
Irfan Zeb, Naser Ahmadi, Ferdinand Flores, Matthew J Budoff
AIMS: Increased epicardial adipose tissue (EAT), pericardial adipose tissue (PAT), periaortic adipose tissue (PaAT), and subcutaneous adipose tissue (SAT) are mediators of metabolic risk, and are associated with the severity of coronary artery calcium (CAC). Aged garlic extract (AGE) has been shown to reduce the progression of coronary atherosclerosis. This study evaluates the effect of AGE with supplements (AGE+S) on EAT, PAT, SAT, and PaAT. METHODS: Sixty asymptomatic participants participated in a randomized trial evaluating the effect of AGE+S versus placebo on coronary atherosclerosis progression, and underwent CAC at baseline and after 12 months of treatment...
November 14, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29135483/coronary-periarteritis-associated-with-multivessel-coronary-artery-disease
#3
Kazushi Sakane, Ryoto Hourai, Masahiro Daimon, Koichi Sohmiya, Hiroko Kuwabara, Takahiro Katsumata, Michishige Ozeki, Yoshinobu Hirose, Nobukazu Ishizaka
No abstract text is available yet for this article.
November 10, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29135482/long-term-darapladib-use-does-not-affect-coronary-plaque-composition-assessed-using-multimodality-intravascular-imaging-modalities-a-randomized-controlled-study
#4
Woong Gil Choi, Megha Prasad, Ryan Lennon, Rajiv Gulati, Abhiram Prasad, Lilach O Lerman, Amir Lerman
BACKGROUND: Lipoprotein-associated phospholipase A2 (Lp-PLA2) may play a role in plaque progression and vulnerability. We aimed to define plaque characteristics on multimodality intravascular imaging in patients with coronary endothelial dysfunction in response to long-term inhibition of Lp-PLA2 by darapladib. PATIENTS AND METHODS: This is a double-blinded, randomized study screening 70 patients, and enrolling 54 patients with suspected ischemia, without obstructive disease on angiography and with coronary endothelial dysfunction by invasive assessment...
November 10, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29120880/culprit-versus-multivessel-coronary-intervention-in-st-segment-elevation-myocardial-infarction-a-meta-analysis-of-randomized-trials
#5
Satyanarayana R Vaidya, Arman Qamar, Sameer Arora, Santhosh R Devarapally, Ashok Kondur, Prashant Kaul
BACKGROUND: The 2015 American College of Cardiology/American Heart Association update on primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) recommended PCI of the non-infarct-related artery at the time of primary PCI (class IIb recommendation). Despite evidence supporting complete revascularization in STEMI, its benefit on mortality rates is uncertain. METHODS: We searched all available databases for randomized controlled trials comparing complete multivessel percutaneous coronary intervention (CMV PCI) with infarct-artery-only revascularization in patients with STEMI...
November 8, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29120879/coronary-perforation-to-left-ventricular-cavity-following-stenting-within-a-myocardial-bridge
#6
Belén Rubio-Alonso, Julio García-Tejada, Carolina Granda-Nistal
No abstract text is available yet for this article.
November 8, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29112510/prediction-of-postpercutaneous-coronary-intervention-myocardial-infarction-insights-from-intravascular-imaging-coronary-flow-and-biomarker-evaluation
#7
Stephen P Hoole, Jules Hernández-Sánchez, Adam J Brown, Joel P Giblett, Martin R Bennett, Nick E J West
BACKGROUND: Percutaneous coronary intervention-induced myocardial infarction (PMI) has prognostic significance. Identifying patients at high risk for PMI is desirable as it may alter strategy and facilitate early preventative therapy. We therefore sought to establish whether preprocedural demographic, interventional (plaque characteristics and coronary microcirculatory function), and inflammatory, endothelial damage, and platelet-derived biomarker data could predict the risk of PMI. PATIENTS AND METHODS: We performed target vessel pressure wire to assess fractional flow reserve, index of microcirculatory resistance (IMR) and coronary flow reserve, plaque characterization by virtual histology intravascular ultrasound, and assayed peripheral biomarkers before uncomplicated PCI in 88 patients...
November 6, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29099395/optical-coherence-tomography-for-visualization-of-subintimal-tracking-during-coronary-intervention
#8
Kenji Sadamatsu, Susumu Takase, Hideki Tashiro
No abstract text is available yet for this article.
November 2, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29049089/coronary-endarterectomy-to-facilitate-bypass-surgery-for-patients-with-extensive-stenting-of-the-left-anterior-descending-artery
#9
Gianfranco Filippone, Claudia Calia, Sara R Vacirca, Giovanni Caruana, Maria R Re, Caterina Giardina, Emanuele Lentini, Cesira Palmeri di Villalba, Vincenzo Argano
No abstract text is available yet for this article.
October 30, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29084042/a-comparison-of-intracoronary-treatment-strategies-for-thrombus-burden-removal-during-primary-percutaneous-coronary-intervention-a-coctail-ii-substudy
#10
Laura Gatto, Alessio Di Landro, Enrico Romagnoli, Valeria Marco, Chiara Russo, Tomasz Pawlowski, Francesco Versaci, Ugo Limbruno, Fausto Castriota, Luca Di Vito, Antonio Trivisonno, Francesco Prati
BACKGROUND: Manual thrombus aspiration and local drug delivery of abciximab have been proposed as a strategy to reduce thrombus burden during percutaneous coronary intervention in patients with ST elevation myocardial infarction; however, the effectiveness of these approaches, is uncertain. In this COCTAIL II substudy, we compared the effect of these strategies on prestenting and poststenting thrombus burden assessed by optical coherence tomography. PATIENTS AND METHODS: COCTAIL II trial enrolled patients with ST elevation myocardial infarction randomized to intralesion (IL, by the ClearWay catheter) versus intracoronary (IC, by the guide catheter) abciximab bolus with or without aspiration thrombectomy (AT)...
October 27, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29084041/comparing-the-effectiveness-of-two-different-decision-aids-for-stable-chest-discomfort
#11
Liis Hinsberg, Felisha Marques, Lauren Leavitt, Christine Skubisz, Karen Sepucha, Jason H Wasfy
BACKGROUND: Decision aids (DAs) have been shown to increase decision quality in randomized controlled trials. This study compared the effectiveness of two different decision aids with different modes of delivery. PARTICIPANTS AND METHODS: Patients with angiogram-proven coronary artery disease (CAD) were eligible to participate and randomly assigned to either a booklet/DVD DA or an online DA. Participants completed a survey after viewing the material that assessed patients' knowledge, treatment preferences, use of and satisfaction with the tool, and open-ended reflections on the treatment decision-making process...
October 27, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29084040/insights-into-coronary-collateral-formation-from-a-novel-porcine-semiacute-infarction-model
#12
Florian Krackhardt, Jonathan M Harnoss, Matthias W Waliszewski, Zully Ritter, Susanne Granzow, Dieter Felsenberg, Konrad Neumann, Lilian O Lerman, Philipp Hillmeister, Rolf Gebker, Ingo Paetsch, Fabian Riediger, Peter Bramlage, Ivo R Buschmann
BACKGROUND: For patients with severe ischemic heart disease, complete revascularization by a percutaneous coronary intervention or coronary artery bypass grafting is often not achieved and may still cause residual angina. In case of progressive coronary artery occlusions, therapeutic arteriogenesis constitutes a promising strategy for increasing blood supply to the ischemic myocardium. Whether the formation of collaterals in the hypofused myocardium is angiogenetic in nature or based on preformed coronary artery anastomoses remains debatable...
October 27, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29076827/one-year-imaging-follow-up-of-a-self-expanding-bifurcation-drug-eluting-stent-and-bioresorbable-scaffold-for-a-complex-bifurcation-lesion
#13
Akihiro Nakajima, Hiroyoshi Kawamoto, Sunao Nakamura, Damras Tresukosol
No abstract text is available yet for this article.
October 25, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29068804/low-energy-cardiac-shockwave-therapy-to-suppress-left-ventricular-remodeling-in-patients-with-acute-myocardial-infarction-a-first-in-human-study
#14
Yuta Kagaya, Kenta Ito, Jun Takahashi, Yasuharu Matsumoto, Takashi Shiroto, Ryuji Tsuburaya, Yoku Kikuchi, Kiyotaka Hao, Kensuke Nishimiya, Tomohiko Shindo, Tsuyoshi Ogata, Ryo Kurosawa, Kumiko Eguchi, Yuto Monma, Sadamitsu Ichijo, Kazuaki Hatanaka, Satoshi Miyata, Hiroaki Shimokawa
OBJECTIVE: Although primary percutaneous coronary intervention (PCI) substantially reduces the mortality of patients with acute myocardial infarction (AMI), left ventricular (LV) remodeling after AMI still remains an important issue in cardiovascular medicine. We have previously demonstrated that low-energy cardiac shockwave (SW) therapy ameliorates LV remodeling after AMI in pigs. In this first-in-human study, we examined the feasibility and the effects of the SW therapy on LV remodeling after AMI in humans...
October 24, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29028740/coronary-vasospasm-a-silent-enemy-in-orthotopic-heart-transplant
#15
Arthur Omondi, David Briceno, Pedro A Villablanca
No abstract text is available yet for this article.
October 12, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29028739/association-of-the-syntax-score-ii-with-cardiac-rupture-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-a-primary-percutaneous-coronary-intervention
#16
Ibrahim Rencuzogullari, Metin Çağdaş, Yavuz Karabağ, Süleyman Karakoyun, Mahmut Yesin, Mustafa O Gürsoy, Sabri Seyis, İnanç Artaç, Doğan İliş, Süleyman Ç Efe, İbrahim H Tanboğa
BACKGROUND: Despite advances in reperfusion strategies, medical therapy, and emergent surgery, cardiac rupture (CR) is still a major lethal complication. Numerous parameters have been found to be associated with CR development after a primary percutaneous coronary intervention (pPCI). SYNTAX Score (SS) and SYNTAX Score II (SSII) have been studied in ST-segment elevation myocardial infarction (STEMI) patients, and higher scores have been associated with higher mortality. However, the relationship between CR and SSII is unclear...
October 12, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29028738/multiple-systemic-embolic-events-in-a-patient-undergoing-primary-percutaneous-coronary-intervention-drop-foot-and-syncope-as-an-unusual-presentation-of-subacute-st-elevation-myocardial-infarction
#17
Martin Geyer, Ingo Sagoschen, Thomas Münzel, Philip Wenzel
No abstract text is available yet for this article.
October 12, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29028737/resting-pd-pa-and-haemodynamic-relevance-of-coronary-stenosis-as-evaluated-by-fractional-flow-reserve
#18
Giuseppe De Luca, Monica Verdoia, Lucia Barbieri, Paolo Marino, Harry Suryapranata
BACKGROUND: Fractional flow reserve (FFR) currently represents the gold standard in the evaluation of the haemodynamic relevance of coronary stenoses. However, both intracoronary and intravenous adenosine may be tolerated poorly by some patients. Therefore, considerable interest had been focused in the last few years on new adenosine-free indexes to define the haemodynamic relevance of coronary stenoses. So far, few data have been reported on resting Pd/Pa and its correlation with FFR as evaluated with high-dose intracoronary adenosine administration, which is the aim of the current study...
October 12, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29016382/myocardial-bridging-in-left-main-coronary-artery
#19
Rong Xu, Yong He, Lin-Jun Xie, Meng-Xi Yang, Zhi-Gang Yang, Ying-Kun Guo
No abstract text is available yet for this article.
October 9, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28984637/what-do-we-tell-patients-with-coronary-artery-disease-about-marijuana-use
#20
Sherrie Khadanga, Philip A Ades
No abstract text is available yet for this article.
October 3, 2017: Coronary Artery Disease
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