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Coronary Artery Disease

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https://www.readbyqxmd.com/read/28207567/relationship-between-r-wave-peak-time-and-no-reflow-in-st-elevation-myocardial-infarction-treated-with-a-primary-percutaneous-coronary-intervention
#1
Metin Çağdaş, Süleyman Karakoyun, İbrahim Rencüzoğullari, Yavuz Karabağ, Mahmut Yesin, Mahmut Uluganyan, Mustafa O Gürsoy, İnanç Artaç, Doğan İliş, Süleyman Ç Efe, Onur Taşar
Coronary no-reflow (NR) is observed in nearly half of ST segment elevation myocardial infarction (STEMI) patients who undergo a primary percutaneous coronary intervention (pPCI) despite epicardial coronary vessel patency. Several methods used to define NR include thrombolysis in myocardial infarction grade, corrected thrombolysis in myocardial infarction frame count, myocardial blush grade, ST-segment resolution, contrast echocardiography, and MRI. The aim of our study was to evaluate the relationship between NR and R-wave peak time (RWPT) measured from infarct-related artery leads METHOD: We enrolled 282 consecutive STEMI patients treated with pPCI in Kafkas University Hospital from January 2014 to January 2015...
February 15, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28121665/body-mass-index-carotid-plaque-and-clinical-outcomes-in-patients-with-coronary-artery-disease
#2
Hyun Woong Park, Ki-Hong Kim, In Girl Song, Taek-Geun Kwon, Wan Ho Kim, Jang-Ho Bae
OBJECTIVES: We evaluated the relationship among BMI, carotid sonographic findings, and long-term (5 years) cardiovascular events in Asian patients with coronary artery disease (CAD). PATIENTS AND METHODS: The study population consisted of 1342 consecutive patients with CAD, who were stratified into four groups according to weight status, as defined by the WHO for the Asian population: underweight (group I: BMI<18.5 kg/m, n=38); normal weight (group II: 18.5≤BMI<23...
January 31, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28118185/comparison-of-plaque-morphology-between-peripheral-and-coronary-artery-disease-from-the-clarity-and-adapt-des-ivus-substudies
#3
Da Yin, Mitsuaki Matsumura, John Rundback, Jason A Yoho, Bernhard Witzenbichler, Gregg W Stone, Gary S Mintz, Akiko Maehara
OBJECTIVE: The aim of this study was to help understand the different outcomes when treating peripheral arterial disease (PAD) versus coronary artery disease (CAD). We compared plaque morphology between PAD and CAD using intravascular ultrasound. METHODS: Complete Lesion Assessment with ffR and IVUS TechnologY (CLARITY) was a prospective, multicenter trial that enrolled 50 PAD patients with a lower extremity wound fed by a tibial or a peroneal artery with diameter stenosis more than 50%...
January 21, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28085708/coronary-spasm-induced-recurrent-ventricular-fibrillation-insights-into-possible-mechanisms-by-a-multimodality-approach
#4
Stephane Fournier, Juan F Iglesias, Valentina Garelli, Marie Guinat, Catalina Trana, Olivier Muller, Pier-Giorgio Masci, Patrizio Pascale, Sarah Hugelshofer, Sophie Degrauwe, Christan Roguelov, Eric Eeckhout, Andrea Zuffi
No abstract text is available yet for this article.
January 12, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28072597/reperfusion-injury-in-st-segment-elevation-myocardial-infarction-the-final-frontier
#5
Gjin Ndrepepa, Roisin Colleran, Adnan Kastrati
ST-segment elevation myocardial infarction is a major cause of morbidity and mortality worldwide. Reperfusion injury (RI) following the opening of an occluded coronary artery mitigates the effect of reperfusion by further accentuating ischemic damage and increasing infarct size. Experimental studies have shown that nearly 50% of final infarct size is attributable to RI, an elusive phenomenon that remains resistant to treatment. This review proposes a hypothesis to explain the failure of strategies that have been used in an attempt to prevent RI...
January 7, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28059849/is-age-an-important-factor-for-vascular-response-to-statin-therapy-a-serial-optical-coherence-tomography-and-intravascular-ultrasound-study
#6
Jiannan Dai, Jingbo Hou, Lei Xing, Haibo Jia, Sining Hu, Tsunenari Soeda, Yoshiyasu Minami, Daniel Ong, Rocco Vergallo, Shaosong Zhang, Hang Lee, Bo Yu, Ik-Kyung Jang
OBJECTIVE: Age-related structural and functional changes in vessel wall may affect the time course of vascular response to statin therapy. In this study, we sought to compare the response of lipid-rich plaque to statin therapy in elderly versus younger patients using optical coherence tomography and intravascular ultrasound. PATIENTS AND METHODS: Sixty-nine patients who underwent serial optical coherence tomography and intravascular ultrasound at the time point of baseline, 6, and 12 months were divided into two groups according to median age: group A (age<57 years, n=35) and group B (age≥57 years, n=34)...
January 4, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28045697/findings-of-optical-frequency-domain-imaging-and-coronary-angioscopy-in-a-lesion-with-spontaneous-recanalization-identified-by-serial-coronary-angiography
#7
Kazuoki Dai, Yasuhisa Nakao, Yusuke Kobayashi, Yuki Ikegami, Arinori Takeuchi, Ayako Harima, Tadanao Higaki, Kuniomi Oi, Tomoharu Kawase, Yasuharu Nakama, Kazuyoshi Suenari, Kenji Nishioka, Koyu Sakai, Masaya Otsuka, Yuji Shimatani, Yoshiko Masaoka, Nobuo Shiode, Ichiro Inoue, Masaharu Ishihara
No abstract text is available yet for this article.
December 29, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/28005559/the-impact-of-blood-pressure-variability-on-coronary-plaque-vulnerability-in-stable-angina-an-analysis-using-optical-coherence-tomography
#8
Rie Aoyama, Hitoshi Takano, Keishi Suzuki, Yoshiaki Kubota, Keisuke Inui, Yukichi Tokita, Wataru Shimizu
BACKGROUND: Blood pressure variability (BPV), especially visit-to-visit BPV, has been reported to be a risk factor for cardiovascular disease. The impact of BPV on coronary plaque vulnerability remains uncertain. The aim of this study was to investigate the relationship between BPV and coronary plaque vulnerability. PATIENTS AND METHODS: From August 2013 to May 2014, 36 patients with both hypertension and stable angina pectoris who underwent a percutaneous coronary intervention guided by frequency-domain optical coherence tomography were investigated retrospectively...
December 21, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/28005558/residual-thromboxane-activity-and-oxidative-stress-influence-on-mortality-in-patients-with-stable-coronary-artery-disease
#9
Anupama Vasudevan, Teodoro Bottiglieri, Kristen M Tecson, Mohanakrishnan Sathyamoorthy, Jeffrey M Schussler, Carlos E Velasco, Luis R Lopez, Caren Swift, Margarita Peterson, Jeanna Bennett-Firmin, Raphael Schiffmann, Peter A McCullough
BACKGROUND: Aspirin use is effective in the prevention of cardiovascular disease; however, not all patients are equally responsive to aspirin. Oxidative stress reflected by F2-isoprostane [8-iso-prostaglandin-F2α (8-IsoPGF2α)] is a potential mechanism of failure of aspirin to adequately inhibit cyclooxygenase-1. The objective was to examine the relation between all-cause mortality and the concentrations of urinary 11-dehydro thromboxane B2 (11dhTxB2) and 8-IsoPGF2α in patients with stable coronary artery disease (CAD)...
December 21, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/27926579/the-influence-of-coronary-plaque-morphology-assessed-by-optical-coherence-tomography-on-final-microvascular-function-after-stenting-in-patients-with-st-elevation-myocardial-infarction
#10
Giovanni L De Maria, Niket Patel, Mathias Wolfrum, Gregor Fahrni, George Kassimis, Italo Porto, Sam Dawkins, Robin P Choudhury, John C Forfar, Bernard D Prendergast, Keith M Channon, Rajesh K Kharbanda, Hector M Garcia-Garcia, Adrian P Banning
OBJECTIVES: The index of microcirculatory resistance (IMR) provides a reproducible assessment of the status of coronary microvasculature in patients with ST-elevation myocardial infarction (STEMI). Frequency-domain optical coherence tomography (FD-OCT) enables detailed assessment of the morphology of coronary plaque.We sought to determine the influence of the initial culprit coronary plaque anatomy within the infarct-related artery on IMR after stenting in STEMI. PATIENTS AND METHODS: In 25 STEMI patients IMR was measured immediately before and after stent implantation...
December 6, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/27906703/left-ventricular-ejection-fraction-and-mortality-in-patients-with-st-elevation-myocardial-infarction-and-bundle-branch-block
#11
M Yldau van der Ende, Minke H T Hartman, Tom Hendriks, Hindrik W van der Werf, Erik Lipsic, Pim van der Harst
BACKGROUND: The aim of our study is to assess the effect of bundle branch block (BBB) on mortality and left ventricular ejection fraction (LVEF) in ST-elevation myocardial infarction (STEMI) patients treated in the current era of percutaneous reperfusion therapy. PATIENTS AND METHODS: In this retrospective cohort study, a total of 1123 STEMI patients treated in the University Medical Center Groningen from January 2011 until May 2013 were included. The follow-up duration was 2-4 years...
November 30, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/28125542/nicorandil-for-maximal-hyperemia-a-theoretical-advantage-awaiting-clinical-significance
#12
Osung Kwon, Duk-Woo Park
No abstract text is available yet for this article.
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28125541/cardiovascular-risk-following-widowhood-increasing-clarity-from-new-research-models
#13
Roger W Bartrop
No abstract text is available yet for this article.
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28045698/the-influence-of-metabolic-syndrome-and-diabetes-mellitus-on-the-n-terminal-pro-b-type-natriuretic-peptide-level-and-its-prognostic-performance-in-patients-with-coronary-artery-disease
#14
Fang-Yang Huang, Yong Peng, Xue-Xue Deng, Bao-Tao Huang, Tian-Li Xia, Yi-Yue Gui, Rui-Shuang Liu, Yong Yang, Xiao-Bo Pu, Shi-Jian Chen, Fei Chen, Ye Zhu, Mao Chen
OBJECTIVES: Our aim was to investigate whether the presence of metabolic syndrome (MetS) and diabetes mellitus (DM) influenced the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level and its prognostic performance in coronary artery disease (CAD). PATIENTS AND METHODS: The present study enrolled a total of 1638 CAD patients. Multivariate regression analyses were carried out to relate NT-proBNP to metabolic components, nondiabetic MetS, DM, and MetS score...
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/27922522/chronic-kidney-disease-predicts-coronary-plaque-vulnerability-an-optical-coherence-tomography-study
#15
Jiannan Dai, Lei Xing, Jingbo Hou, Haibo Jia, Sining Hu, Jinwei Tian, Lin Lin, Lulu Li, Yinchun Zhu, Gonghui Zheng, Shaosong Zhang, Bo Yu, Ik-Kyung Jang
OBJECTIVE: The addition of cystatin C to creatinine in calculating the estimated glomerular filtration rate (eGFR) is known to improve the risk prediction for cardiovascular events. We sought to investigate the associations between eGFRs calculated by three Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations and coronary plaque phenotype by optical coherence tomography. PATIENTS AND METHODS: We analyzed 181 nonculprit plaques from 116 coronary artery disease patients...
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/27906702/diagnostic-accuracy-of-intraluminal-blood-speckle-intensity-on-intravascular-ultrasound-for-physiological-assessment-of-coronary-artery-stenosis
#16
Yuichi Saito, Hideki Kitahara, Takashi Nakayama, Yoshihide Fujimoto, Yoshio Kobayashi
OBJECTIVES: The difference in intraluminal intensity of blood speckle (IBS) on integrated backscatter intravascular ultrasound (IVUS) across the coronary stenosis was reportedly correlated with fractional flow reserve (FFR) in the left descending coronary artery. The aim of this study was to investigate the novel physiological assessment using IVUS in all coronary arteries. PATIENTS AND METHODS: Fifty-four patients with 57 coronary lesions underwent both FFR and IVUS...
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/27879518/three-month-evaluation-of-strut-healing-using-a-novel-optical-coherence-tomography-analytical-method-following-bioresorbable-polymer-everolimus-eluting-stent-implantation-in-humans-the-timeless-study
#17
Boris Vesga, Hector Hernandez, Miguel Moncada, Pawel Gasior, Sergio Higuera, Antonio Dager, Camilo Arana, Juan A Delgado, Philippe Généreux, Akiko Maehara, Juan F Granada
AIMS: Bioresorbable polymer drug-eluting stent technologies have been considered to have the potential to enhance vascular healing by reducing polymer exposure to the vessel wall, potentially allowing the earlier discontinuation of dual antiplatelet therapy. At present, the early vascular healing response to this type of technologies is still unclear. PATIENTS AND METHODS: The TIMELESS study is a multicenter, prospective, single-arm study that enrolled real-world patients undergoing percutaneous coronary intervention...
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/27845998/bioresorbable-scaffolds-compared-with-everolimus-eluting-stents-for-the-treatment-of-chronic-coronary-total-occlusion-clinical-and-angiographic-results-of-a-matched-paired-comparison
#18
Christine Kugler, Sinisa Markovic, Wolfgang Rottbauer, Jochen Wöhrle
OBJECTIVES: Data on bioresorbable vascular scaffolds for recanalization of chronic total occlusions (CTOs) are limited. We compared the bioresorbable scaffold Absorb with everolimus-eluting stents for the treatment of true CTO. METHODS: After recanalization of CTO, 15 lesions treated with the bioresorbable scaffold Absorb were matched with 15 lesions receiving everolimus-eluting stent (EES) (http://www.clinicaltrials.gov NCT02162082). Match criteria were presence of diabetes mellitus, total device length and maximal device diameter...
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/27845997/impact-of-diabetes-duration-on-3-year-clinical-outcomes-following-coronary-revascularization
#19
Hai-Yang Gao, Er-Li Zhang, Qing-Rong Liu, Hong-Qiu Gu, Heng Zhang, Zhe Zheng, Yue-Jin Yang, Run-Lin Gao, Yong-Jian Wu
OBJECTIVE: The aim of this study was to evaluate the impact of diabetes duration on long-term clinical outcomes after drug-eluting stent (DES) implantation or coronary artery bypass grafting (CABG). METHODS: A total of 820 diabetic patients treated with initial DES (n=451) or CABG (n=369) were consecutively enrolled in this single-center follow-up study. The main outcomes included major adverse cardiac events and major adverse cardiac or cerebrovascular events (MACCEs)...
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/27845996/acute-coronary-syndromes-in-patients-with-hiv
#20
Valmiki K Seecheran, Stanley L Giddings, Naveen A Seecheran
Highly active antiretroviral treatment (HAART) has considerably increased the life expectancy of patients infected with HIV. Coronary artery disease is a leading cause of mortality in patients infected with HIV. This is primarily attributed to their increased survival, HAART-induced metabolic derangements, and to HIV itself. The pathophysiology of atherosclerosis in HIV is both multifactorial and complex - involving direct endothelial injury and dysfunction, hypercoagulability, and a significant contribution from traditional cardiac risk factors...
March 2017: Coronary Artery Disease
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