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Coronary Artery Disease

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https://www.readbyqxmd.com/read/28926354/neointimal-coverage-of-jailed-side-branches-in-coronary-bifurcation-lesions-an-optical-coherence-tomography-analysis
#1
Teruyoshi Kume, Ryotaro Yamada, Koyama Terumasa, Tomoko Tamada, Koichiro Imai, Kenzo Fukuhara, Yutaka Goryo, Ai Kawamura, Okamoto Hiroshi, Yoji Neishi, Shiro Uemura
OBJECTIVES: The jailed strut at the side-branch (SB) orifice may be a cause of delayed neointimal coverage and SB flow disturbance after single stenting to bifurcation. The aim of this study was to characterize the exact relationship between the jailed strut pattern at the SB orifice immediately after stent implantation and neointimal coverage of the jailed SB orifice in the chronic phase. PATIENTS AND METHODS: A total of 29 bifurcation (left anterior descending coronary artery and diagonal branch) lesions treated by optical coherence tomography-guide single-stent implantation and followed at 18 months after a percutaneous coronary intervention were included in this study...
September 18, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28914638/long-term-risk-and-predictors-of-cardiovascular-death-in-stable-coronary-artery-disease-the-coronor-study
#2
Christophe Bauters, Olivier Tricot, Thibaud Meurice, Nicolas Lamblin
BACKGROUND: There is limited knowledge on the residual risk of cardiovascular death (CVD) in patients with stable coronary artery disease (CAD) who receive modern secondary prevention. Our aim was to analyze the causes of death and to determine predictors of CVD in the 5-year CORONOR registry. METHODS: We studied 4184 consecutive CAD outpatients who were free from any myocardial infarction (MI) or coronary revascularization for more than 1 year at inclusion. Antithrombotics were prescribed in 99%, statins in 92%, inhibitors of renin-angiotensin system in 82%, and β-blockers in 79%; 86% had prior coronary revascularization...
September 13, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28902718/effect-of-drug-coated-balloon-on-stent-restenosis-neointimal-proliferation-and-coronary-dissection-an-optical-coherence-tomography-analysis
#3
Taku Fukushima, Takashi Ashikaga, Shunji Yoshikawa, Yu Hatano, Daisuke Ueshima, Takanobu Yamamoto, Maejima Yasuhiro, Mitsuaki Isobe
AIM: The aim of this study was to assess the acute and mid-term effects of drug-coated balloon (DCB) in terms of the healing process of non-flow-limiting dissections and changes in the neointimal area after DCB treatment using frequency domain optical coherence tomography (FD-OCT). PATIENTS AND METHODS: Thirty-six consecutive patients with in-stent restenosis pretreated with a scoring balloon were evaluated (19 and 17 patients with and without a DCB, respectively)...
September 11, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28885395/recurrent-myocardial-infarction-in-an-aneurysmal-coronary-artery-managed-with-stent-grafts
#4
Marcel A Beijk, Jose P S Henriques, Robbert J de Winter, Jan J Piek
No abstract text is available yet for this article.
September 6, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28885394/pleiotrophin-levels-are-associated-with-improved-coronary-collateral-circulation
#5
Pinar Türker Duyuler, Serkan Duyuler, Murat Gök, Harun Kundi, Canan Topçuoğlu, Ümit Güray
OBJECTIVES: Elucidation of the underlying mechanisms of angiogenesis and arteriogenesis in coronary collateral formation is necessary for new therapies. Pleiotrophin is a secreted multifunctional cytokine and associated with the formation of functional cardiovascular neovascularization in a series of experimental animal models. We aimed to evaluate the serum levels of pleiotrophin in patients with chronic total coronary artery occlusion and poor or good collateral development. METHODS: We included 88 consecutive patients (mean age of the entire population: 63...
September 6, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28885393/the-association-between-red-cell-distribution-width-erythropoietin-levels-and-coronary-artery-disease
#6
Yuanmin Li, Min Li, Yufang Teng, Chen Zhang, Qinghua Liu, Haifeng Hou
BACKGROUND: Red cell distribution width (RDW) is a cardiac marker for risk stratification and prognostic evaluation of coronary artery disease (CAD); however, the underlying mechanism remains unclear. Erythropoietin (EPO), a crucial factor affecting erythropoiesis, has been reported to be a protective molecule regulating the process of myocardial ischemia and relevant damage. No study has as yet reported the relationship between RDW and endogenous EPO in CAD patients. This cross-sectional study aimed to establish the association between endogenous EPO levels and increases in RDW in CAD patients...
September 6, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28857776/cha2ds2-vasc-score-and-exercise-capacity-of-patients-with-coronary-artery-disease-participating-in-cardiac-rehabilitation-programs
#7
Feras Haskiah, Yacov Shacham, Saar Minha, Zach Rozenbaum, David Pereg
BACKGROUND: Exercise based cardiac rehabilitation improves prognosis and quality of life in patients with coronary artery disease. We aimed to investigate whether the CHA2DS2-VASc score may be a predictor of improvement in exercise capacity in acute coronary syndrome (ACS) patients participating in a cardiac rehabilitation program. METHODS: Included were patients following a hospital admission due to ACS and were subsequently referred for an exercise based cardiac rehabilitation during 2010-2015...
August 29, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28834792/antiplatelet-treatment-in-diabetic-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention-a-greek-antiplatelet-registry-substudy
#8
Michalis Hamilos, Stylianos Petousis, Ioanna Xanthopoulou, John Goudevenos, John Kanakakis, George Sitafidis, Manolis Vavouranakis, Emmanuel Skalidis, George Kochiadakis, John Lekakis, Panos E Vardas, Dimitrios Alexopoulos
BACKGROUND AND AIMS: We compared the clinical outcome of diabetic versus nondiabetic patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) in the GReek AntiPlatElet (GRAPE) registry. PATIENTS AND METHODS: GRAPE is a prospective observational study, focusing on contemporary antiplatelet use in moderate-risk to high-risk ACS patients receiving PCI. Major adverse cardiovascular events (MACE), (composite of death, nonfatal myocardial infarction, urgent revascularization, and stroke) and bleeding events (Bleeding Academic Research Consortium definition) at 1 year of follow-up were analyzed using propensity score adjustment...
August 23, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28825931/brachial-ankle-pulse-wave-velocity-as-a-marker-of-adverse-events-following-non-st-elevation-myocardial-infarction-a-new-standard-in-risk-stratification
#9
Eric A Secemsky, Robert W Yeh
No abstract text is available yet for this article.
August 18, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28799980/retrieval-of-a-fractured-angioplasty-guidewire-after-percutaneous-retrograde-revascularization-of-coronary-chronic-total-occlusion
#10
Stefan Baumann, Daniel Rupp, Tobias Becher, Michael Behnes, Maliha Sadick, Martin Borggrefe, Ibrahim Akin
No abstract text is available yet for this article.
August 9, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28777120/multicenter-aids-cohort-study-quantitative-coronary-plaque-progression-study-rationale-and-design
#11
Rine Nakanishi, Wendy S Post, Kazuhiro Osawa, Eranthi Jayawardena, Michael Kim, Nasim Sheidaee, Negin Nezarat, Sina Rahmani, Nicholas Kim, Nicolai Hathiramani, Shriraj Susarla, Frank Palella, Mallory Witt, Michael J Blaha, Todd T Brown, Lawrence Kingsley, Sabina A Haberlen, Christopher Dailing, Matthew J Budoff
BACKGROUND AND AIM: The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. The Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study is a large prospective multicenter study quantifying progression of coronary plaque assessed by serial coronary computed tomography angiography (CTA). PATIENTS AND METHODS: HIV-infected and uninfected men who were enrolled in the Multicenter AIDS Cohort Study Cardiovascular Substudy were eligible to complete a follow-up contrast coronary CTA 3-6 years after baseline...
August 2, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28763313/generalizability-of-excel-and-noble-results-to-a-large-registry-population-with-unprotected-left-main-coronary-artery-disease
#12
Pil Hyung Lee, Se Hun Kang, Seungbong Han, Jung-Min Ahn, Jae Seok Bae, Cheol Hyun Lee, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Duk-Woo Park, Seung-Jung Park
OBJECTIVE: The aim of this study was to determine how trial-based findings of EXCEL and NOBLE might be interpreted and generalizable in 'real-world' settings with comparison of data from the large-scaled, all-comer Interventional Research Incorporation Society-Left MAIN Revascularization (IRIS-MAIN) registry. PATIENTS AND METHODS: We compared baseline clinical and procedural characteristics and also determined how the relative treatment effect of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) was different in EXCEL and NOBLE, compared with those of the multicenter, IRIS-MAIN registry (n=2481)...
July 31, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28746145/treatment-and-outcomes-of-type-2-myocardial-infarction-and-myocardial-injury-compared-with-type-1-myocardial-infarction
#13
Nathaniel R Smilowitz, Pritha Subramanyam, Eugenia Gianos, Harmony R Reynolds, Binita Shah, Steven P Sedlis
BACKGROUND: Type 2 myocardial infarction (MI) is defined by a rise and fall of cardiac biomarkers and evidence of ischemia without unstable coronary artery disease (CAD) because of a mismatch in myocardial oxygen supply and demand. Myocardial injury is similar but does not fulfill the clinical criteria for MI. There is uncertainty in terms of the clinical characteristics, management, and outcomes of type 2 MI and myocardial injury in comparison with type 1 MI. PATIENTS AND METHODS: Patients admitted to a Veterans Affairs tertiary care hospital with a rise and fall in cardiac troponin were identified...
July 25, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28737526/serial-measurements-of-neutrophil-gelatinase-associated-lipocalin-prognostic-value-in-patients-with-st-segment-elevation-myocardial-infarction-treated-with-a-primary-percutaneous-coronary-intervention
#14
Yeong-Min Lim, Jae Youn Moon, Daniel Min, Sang-Hoon Kim, Woo-In Yang, Won-Jang Kim, Jung-Hoon Sung, In Jai Kim, Sang-Wook Lim, Dong-Hun Cha
BACKGROUND: There are no previous data on serial changes in neutrophil gelatinase-associated lipocalin (NGAL) levels in ST-segment elevation myocardial infarction (STEMI) patients before and after a primary percutaneous coronary intervention (pPCI). The aim of the present study was to evaluate the prognostic value of serial NGAL measurements in patients with STEMI treated by pPCI. MATERIALS AND METHODS: We identified 169 STEMI patients who underwent pPCI within 12 h of symptom onset and had plasma NGAL measurements before (pre-NGAL) and 6 h after (post-NGAL) pPCI...
July 21, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28731889/stent-thrombosis-with-bioabsorbable-polymer-drug-eluting-stents-insights-from-the-food-and-drug-administration-database
#15
Abdur R Khan, Avnish Tripathi, Talha A Farid, Bilal Abaid, Deepak L Bhatt, Jon R Resar, Michael P Flaherty
BACKGROUND: SYNERGY, a bioabsorbable polymer-based, everolimus-eluting stent (BP-DES), recently received regulatory approval in the USA for use in percutaneous coronary interventions. Yet, information on the safety of BP-DES in routine clinical practice is limited. Our aim was to compare the safety of the recently approved BP-DES with current durable polymer drug-eluting stents (DP-DES) by analyzing adverse events, namely, stent thrombosis (ST), reported to the Manufacturer and User Facility Device Experience (MAUDE) database...
July 20, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28731888/elevated-plasma-levels-of-mac-2-binding-protein-predict-poor-cardiovascular-outcomes-in-patients-with-acute-coronary-syndrome
#16
Hao Xie, Zhun Zhang, Liming Chen, Pu Zhang, Yuqi Cui, Hang Liu, Hongrui Ma, Yufan Jiang, Ying Wang, Le Yang, Hongpeng Wu, Lianqun Cui
BACKGROUND: Mac-2 binding protein (M2BP) is an inflammatory glycoprotein associated with carotid atherosclerosis and all-cause mortality in patients with suspected coronary artery diseases. We aimed to explore the potential association of plasma M2BP levels with unstable plaque morphology and cardiovascular outcomes in patients with acute coronary syndrome (ACS). PATIENTS AND METHODS: We compared plasma M2BP levels among three groups: 216 patients with ACS, 82 patients with stable angina pectoris, and 50 controls...
July 20, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28727582/rapidly-growing-coronary-artery-aneurysm-associated-with-pericarditis
#17
Hiroyoshi Mori, Kohei Wakabayashi, Hiroshi Suzuki
No abstract text is available yet for this article.
July 19, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28723830/early-versus-delayed-coronary-artery-bypass-graft-surgery-for-patients-with-non-st-elevation-myocardial-infarction
#18
Le Dung Ha, Gbolahan Ogunbayo, Ayman Elbadawi, Odunayo Olorunfemi, Adrian Messerli
BACKGROUND: Although coronary artery bypass graft surgery (CABG) has been proven to have mortality and morbidity benefits in patients with non-ST elevation myocardial infarction and multivessel disease, the appropriate timing of this procedure remains unclear. Therefore, we proposed a propensity score-matched analysis comparing the clinical outcomes between patients who underwent CABG within the first 48 h of admission (early CABG) and patients who underwent CABG after 48 h of admission (delayed CABG)...
July 18, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28723829/prognostic-implication-of-early-ventricular-fibrillation-among-patients-with-st-elevation-myocardial-infarction
#19
Kristel E Medina-Rodríguez, Manuel Almendro-Delia, Ángel García-Alcántara, José J Arias-Garrido, Juan C Rodríguez-Yáñez, Gemma Alonso-Muñoz, Rafael de la Chica-Ruiz-Ruano, Antonio Reina-Toral, Antonio Varela-López, José A Arboleda-Sánchez, Ana M Poullet-Brea, Benito Zaya-Ganfo, Michel Butrón-Calderón, Maria J Cristo-Ropero, Rafael Hidalgo-Urbano, Juan C García-Rubira
OBJECTIVE: The aim of this study was to analyze the prognosis of patients presenting early ventricular fibrillation (VF) in the setting of ST elevation myocardial infarction (STEMI). PATIENTS AND METHODS: Among patients included in the ARIAM (Análisis del Retraso en el Infarto Agudo de Miocardio) registry with the diagnosis of STEMI, those who received primary revascularization and were admitted in the first 12 h were analyzed retrospectively. RESULTS: From January 2007 to January 2012, 8340 patients were included in the STEMI cohort and 680 (8...
July 18, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28708660/a-novel-predictor-of-adverse-outcomes-after-st-elevation-myocardial-infarction-deterioration-of-atrioventricular-conduction
#20
Gilad Margolis, Shafik Khoury
No abstract text is available yet for this article.
July 13, 2017: Coronary Artery Disease
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