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Coronary Artery Disease

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https://www.readbyqxmd.com/read/29781836/relationship-between-left-main-coronary-artery-plaque-burden-and-nonleft-main-coronary-atherosclerosis-results-from-the-prospect-study
#1
Takehisa Shimizu, Gary S Mintz, Bernard De Bruyne, Naim Z Farhat, Shinji Inaba, Yang Cao, Steven P Marso, Giora Weisz, Patrick W Serruys, Gregg W Stone, Akiko Maehara
OBJECTIVES: Whether the severity of left main coronary artery (LMCA) disease reflects LMCA and overall coronary atherosclerotic burden is not known. We aimed to assess nonculprit LMCA disease characteristics and the relationship with atherosclerosis in the rest of the coronary arteries as well as patient outcomes. PATIENTS AND METHODS: In the PROSPECT study, 697 patients with acute coronary syndromes underwent three-vessel gray-scale and radiofrequency intravascular ultrasound after percutaneous coronary intervention...
May 17, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29762146/an-augmented-pd-pa-response-after-contrast-injection-during-intravenous-adenosine-induced-hyperemia
#2
Jelmer Westra, Niels R Holm, Evald H Christiansen, Troels Thim
No abstract text is available yet for this article.
May 14, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29746260/confirmed-coronary-spasm-at-the-culprit-vessel-of-plaque-erosion-in-a-patient-with-new-onset-ventricular-fibrillation
#3
Kazuma Tashiro, Hiroyoshi Mori, Hiromoto Sone, Yousuke Takei, Masahiro Sasai, Atsuo Maeda, Tokutada Sato, Hiroshi Suzuki
No abstract text is available yet for this article.
May 9, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29746261/optical-coherence-tomography-guided-percutaneous-coronary-stenting-for-right-coronary-artery-malperfusion-due-to-acute-type-a-aortic-dissection
#4
Yusaku Shibata, Nobuaki Kobayashi, Noritake Hata, Wataru Shimizu
No abstract text is available yet for this article.
May 8, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29738342/association-between-interleukin-35-polymorphisms-and-coronary-heart-disease-in-the-chinese-zhuang-population-a-case-control-study
#5
Yingzhong Lin, Yan Xue, Xinshun Huang, Jianyong Lu, Zicong Yang, Jing Ye, Shu Zhang, Ling Liu, Yu Liu, Ying Shi
OBJECTIVES: Inflammatory cytokines play an important role in the pathogenesis of cardiovascular disease. Few studies have investigated the association between interleukin-35 (IL-35) genetic variants and the risk of coronary heart disease (CHD). We examined the association between IL-35 polymorphisms and CHD in the Chinese Zhuang population. PATIENTS AND METHODS: A total of 707 CHD patients and 707 age-matched and sex-matched controls were enrolled in this case-control study...
May 5, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29738341/effect-of-pitavastatin-and-atorvastatin-on-regression-of-atherosclerosis-assessed-using-intravascular-ultrasound-a-meta-analysis
#6
Hui Liu, Mingjun Zhang, Delong Li, Jingjing Tian, Xuyang Wang, Jinyu Pan, Dian Liu, Xiaowei Li, Fengshuang An
BACKGROUND: The aim of this study is to compare the efficacy and safety of pitavastatin and atorvastatin using data from randomized-controlled trial pooled together by means of a meta-analysis and decide which is better. METHODS: PubMed, CENTRAL, Web of Knowledge, and ClinicalTrials.gov website were searched for randomized-controlled trials published until October 2016. Eligible studies comparing pitavastatin with atorvastatin head to head and reporting the outcome of low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), glycated hemoglobin, and intravascular ultrasound evaluation were enrolled...
May 5, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29708887/twelve-month-clinical-outcomes-of-acute-non-st-versus-st-segment-elevation-myocardial-infarction-patients-with-reduced-preprocedural-thrombolysis-in-myocardial-infarction-flow-undergoing-percutaneous-coronary-intervention
#7
Ju Yeol Baek, Tae Soo Kang, Seung-Woon Rha, Byoung Geol Choi, Sang Ho Park, Myung Ho Jeong
BACKGROUND: Reduced preprocedural thrombolysis in myocardial infarction (TIMI) flow in patients with ST-segment elevation myocardial infarction (STEMI) is known to be associated with increased mortality. However, clinical implications of reduced preprocedural TIMI flow in patients with non-ST-segment elevation myocardial infarction (NSTEMI) have not been fully elucidated as yet. The aim of the present study was to compare the clinical influence of reduced preprocedural TIMI flows between patients with STEMI and NSTEMI undergoing percutaneous coronary intervention (PCI)...
April 27, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29697483/role-of-optical-coherence-tomography-in-identifying-sub-optimal-stent-positioning-and-predicting-major-adverse-cardiac-events-in-a-comparative-study-with-angiography-a-clio-opci-ii-sub-study
#8
Laura Gatto, Marco Golino, Valeria Marco, Alessio La Manna, Francesco Burzotta, Massimo Fineschi, Giovanni Ruscica, Alessandro Di Giorgio, Alberto Boi, Enrico Romagnoli, Mario Albertucci, Francesco Prati
BACKGROUND: Quantitative coronary angiography (QCA) is the gold standard for evaluating correct stenting, despite its limitation in recognizing features indicative of suboptimal deployment. This subanalysis of the CLI-OPCI II registry addressed the role of optical coherence tomography (OCT) to verify whether suboptimal OCT deployment occurs in the presence of an optimal angiographic result. PATIENTS AND METHODS: We retrospectively analyzed 125 lesions in the 105 patients with major adverse cardiac events of the CLI-OPCI II...
April 24, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29688904/chronic-total-occlusion-intervention-of-the-non-infarct-related-artery-in-acute-myocardial-infarction-patients-the-korean-multicenter-chronic-total-occlusion-registry
#9
Ji Young Park, Byoung Geol Choi, Seung-Woon Rha, Tae Soo Kang, Cheol Ung Choi, Cheol Woong Yu, Hyeon-Cheol Gwon, In-Ho Chae, Hyo-Soo Kim, Hun Sik Park, Seung-Hwan Lee, Moo-Hyun Kim, Seung-Ho Hur, Yangsoo Jang
BACKGROUND: The Korean chronic total occlusion (CTO) registry was collected prospectively from 26 cardiovascular centers since May 2007. The aim of this study is to investigate the impact of a successful staged percutaneous coronary intervention (PCI) of CTO lesions in acute myocardial infarction (AMI) patients on clinical outcomes. PATIENTS AND METHODS: Among 2813 patients who underwent a staged PCI because of CTO lesions, 422 (15%) patients underwent primary PCI because of AMI...
April 23, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29683805/the-effect-of-obesity-on-long-term-survival-and-health-related-quality-of-life-after-coronary-artery-bypass-grafting-a-12-year-follow-up
#10
Matti Hokkanen, Otso Järvinen, Heini Huhtala, Jari Laurikka
OBJECTIVE: The proportion of obese patients undergoing coronary artery bypass graft (CABG) surgery is increasing. In this study, our main objective was to assess the effect of obesity on long-term mortality and changes in quality of life (QoL) after GABG. MATERIALS AND METHODS: Data of 508 patients who underwent isolated GABG were prospectively collected. RAND-36 Health Survey (RAND-36) was used as an indicator of QoL. BMI was used to assess obesity, and the analysis was based primarily on two patient groups: BMI less than 30 kg/m (408 patients) and BMI of at least 30 (100 patients)...
April 20, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29668554/long-term-clinical-outcomes-after-coronary-artery-bypass-graft-versus-everolimus-eluting-stent-implantation-in-chronic-hemodialysis-patients
#11
Yoshitaka Kumada, Hideki Ishii, Toru Aoyama, Daisuke Kamoi, Takashi Sakakibara, Norio Umemoto, Ryuta Ito, Hiroshi Takahashi, Toyoaki Murohara
BACKGROUND: It remains controversial whether coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI) should be optimized to treat coronary artery disease in patients on chronic hemodialysis (HD). Recently, further refinement of drug-eluting stents, such as the everolimus-eluting stent (EES), has led to marked development in this field. We compared long-term clinical outcomes after CABG versus PCI with EES implantation in patients on chronic HD. PATIENTS AND METHODS: We compared 138 patients undergoing CABG and 187 patients treated with EES implantation...
April 17, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29664742/the-orbita-trial-and-the-future-of-percutaneous-coronary-intervention-for-stable-angina
#12
Maayan Konigstein, Ori Ben-Yehuda
No abstract text is available yet for this article.
April 16, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29652673/inflammation-and-coronary-artery-disease-from-pathophysiology-to-canakinumab-anti-inflammatory-thrombosis-outcomes-study-cantos
#13
Mahboob Ali, Sameh Girgis, Atif Hassan, Steven Rudick, Richard C Becker
The worldwide prevalence of cardiovascular disease in general and atherosclerotic coronary artery disease in particular is a health and economic concern of unparalleled proportion. Despite a long history of astute observations beginning in 1575 made by Fallopius, followed by those of von Rokatansky, Virchow, Osler, and Ross, and incremental knowledge of the pathobiology of atherosclerosis to include varying stages of inflammation, response to internally and externally mediated vascular injury, and impaired homeostasis, gaps in the field's understanding persist...
April 12, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29652672/early-discontinuation-of-prasugrel-or-clopidogrel-in-acute-coronary-syndromes-insights-from-the-trilogy-acs-trial
#14
Andrew T Yan, Matthew T Roe, Megan Neely, Derek D Cyr, Harvey White, Keith A A Fox, Dorairaj Prabhakaran, Paul W Armstrong, Erik M Ohman, Shaun G Goodman
BACKGROUND: In the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes (TRILOGY ACS) trial of patients with non-ST-segment elevation acute coronary syndrome managed medically without revascularization, treated with prasugrel versus clopidogrel for less than or equal to 30 months after index acute coronary syndrome, post-hoc analyses showed a divergence of treatment effect in favor of prasugrel after 12 months. Potential influential factors, including a potential late treatment effect after early study drug discontinuation in the intention-to-treat analysis, have not been explored...
April 12, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29649071/predictors-of-early-scaffold-thrombosis-results-from-the-multicenter-prospective-german-austrian-absorb-registry
#15
Jochen Wöhrle, Holger M Nef, Christoph Naber, Stephan Achenbach, Thomas Riemer, Julinda Mehilli, Thomas Münzel, Steffen Schneider, Sinisa Markovic, Julia Seeger, Wolfgang Rottbauer, Thomas Pfannebecker, Gert Richardt, Ralf Zahn, Tommaso Gori, Johannes Kastner, Axel Schmermund, Christian W Hamm
BACKGROUND: In randomized clinical trials, the risk of thrombotic events with the absorb bioresorbable vascular scaffold (BVS) was significantly higher than with metallic drug-eluting stents. We evaluated predictors of scaffold thrombosis in the large-scale, multicenter German-Austrian ABSORB RegIstRy. METHODS AND RESULTS: 3178 patients with treatment of 4252 lesions using 5020 scaffolds were included. Follow-up rate at 6 months was 97.4%. Forty-five (1.42%) patients experienced definite/probable scaffold thrombosis during follow-up...
April 11, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29649070/an-accidentally-crushed-stent-identified-by-optical-coherence-tomography
#16
Rasha Al-Bawardy, Sunu Thomas, Duke Cameron, Ik-Kyung Jang
No abstract text is available yet for this article.
April 11, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29642228/an-observational-study-of-clinical-outcomes-of-everolimus-eluting-bioresorbable-scaffolds-comparing-the-procedural-use-of-optical-coherence-tomography-against-angiography-alone
#17
Stephen Hamshere, Alex Byrne, Oliver Guttmann, Paul Rees, Christos Bourantas, Roshan Weerakody, Andrew Wragg, Charles Knight, Anthony Mathur, Daniel A Jones
OBJECTIVES: The introduction of the bioresorbable vascular scaffold (BVS) has led to new avenues of coronary intervention; however, there have been concerns raised regarding the mechanical properties of BVS and the resulting in-stent thrombosis. We aim to assess whether intracoronary imaging improves outcome in patients following BVS implantation. PATIENTS AND METHODS: All patients undergoing percutaneous coronary intervention using BVS at a single centre between June 2013 and June 2016 were included in this study (n=79)...
April 10, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29621009/percutaneous-coronary-intervention-for-treating-de-novo-lesions-in-small-coronary-vessels-initial-experience-with-the-essential-paclitaxel-coated-balloon
#18
Rosa Alba Abellas-Sequeiros, Javier Benezet, Antonio Agarrado Luna, Jesús Oneto Otero, Jean-Pierre Déry, Tomas Cieza, Robert DeLarochellière, Lluis Duocastella, Alex Gomez, Maria Molina, Lluis Asmarats, Emilie Pelletier-Beaumont, Rishi Puri, Josep Rodés-Cabau
BACKGROUND: Paclitaxel-coated balloon (PCB) coronary angioplasty is an alternative treatment for de-novo coronary lesions in small vessels. This study with the new Essential PCB aimed to evaluate early and mid-term clinical outcomes following angioplasty with the Essential PCB in the treatment of de-novo lesions in small vessels. PATIENTS AND METHODS: We included all patients who underwent PCB angioplasty for treating de-novo coronary lesions in small vessels (reference diameter <2...
April 4, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29620557/impact-of-paclitaxel-coated-balloon-versus-newer-generation-drug-eluting-stent-on-periprocedural-myocardial-infarction-in-stable-angina-patients
#19
Ae-Young Her, Yong Hoon Kim, Scot Garg, Eun-Seok Shin
OBJECTIVES: Periprocedural myocardial infarction (PMI) is reported to be associated with adverse long-term clinical outcomes. This study compared the rates of PMI following treatment of de novo coronary lesions using either a paclitaxel-coated balloon (PCB) or a newer-generation drug-eluting stent (DES). PATIENTS AND METHODS: We compared the incidence of PMI in propensity-matched patients with stable angina pectoris and single-vessel de novo coronary lesions who underwent treatment with a PCB or newer-generation DES...
April 3, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29613857/a-favorable-neointimal-proliferation-healing-process-of-large-drug-eluting-stent-malapposition
#20
Cristina Aurigemma, Francesco Burzotta, Filippo Crea, Carlo Trani
No abstract text is available yet for this article.
April 2, 2018: Coronary Artery Disease
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