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Journal of Cardiovascular Electrophysiology

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https://www.readbyqxmd.com/read/28639747/the-effect-of-activation-rate-on-left-atrial-bipolar-voltage-in-patients-with-paroxysmal-atrial-fibrillation
#1
Steven E Williams, Nick Linton, Louisa O'Neill, James Harrison, John Whitaker, Rahul Mukherjee, Christopher A Rinaldi, Jaswinder Gill, Steven Niederer, Matthew Wright, Mark O'Neill
INTRODUCTION: Bipolar voltage is used during electroanatomic mapping to define abnormal myocardium, but the effect of activation rate on bipolar voltage is not known. We hypothesized that bipolar voltage may change in response to activation rate. By examining corresponding unipole signals we sought to determine the mechanisms of such changes. METHODS AND RESULTS: LA extrastimulus mapping was performed during CS pacing in 10 patients undergoing 1(st) time paroxysmal atrial fibrillation ablation...
June 22, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28639728/prospective-use-of-ablation-index-targets-improves-clinical-outcomes-following-ablation-for-atrial-fibrillation
#2
Ahmed Hussein, Moloy Das, Vivek Chaturvedi, Issa Khalil Asfour, Niji Daryanani, Maureen Morgan, Christina Ronayne, Matthew Shaw, Richard Snowdon, Dhiraj Gupta
AIMS: Late recovery of ablated tissue leading to reconnection of pulmonary veins remains common following radiofrequency catheter ablation for AF. Ablation Index (AI), a novel ablation quality marker, incorporates contact force (CF), time and power in a weighted formula. We hypothesized that prospective use of our previously-published derived AI targets would result in better outcomes when compared to CF-guided ablation. METHODS: 89 consecutive drug-refractory AF patients (49% paroxysmal) underwent AI-guided ablation (AI-group)...
June 22, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28635186/catheter-ablation-of-atrial-fibrillation-with-box-isolation-of-fibrotic-areas-lessons-on-fibrosis-distribution-and-extent-clinical-characteristics-and-their-impact-on-long-term-outcome
#3
Doreen Schreiber, Andreas Rieger, Fabian Moser, Hans Kottkamp
INTRODUCTION: The BIFA concept (box isolation of fibrotic areas) supplementing pulmonary vein isolation (PVI) was implemented in atrial fibrillation (AF) patients with fibrotic atrial cardiomyopathy (FACM) to improve catheter ablation outcomes. METHODS AND RESULTS: 92 patients with FACM underwent PVI+BIFA. We investigated patient characteristics (58 persistent/34 paroxysmal,68±8y,LA 44±7mm,CHA2 DS2 -VASc 2.6±1.3,FACM I:15.2%,II:53.3%,III:26.1%,IV:5.4%), periprocedural data concerning fibrosis extent/distribution and their impact on outcome...
June 21, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28635147/life-threatening-aortic-dissection-with-cardiac-tamponade-during-catheter-ablation-for-ventricular-tachycardia-originating-from-left-coronary-cusp
#4
Kenji Kuroki, Akira Sato, Fumi Yamagami, Akihiko Nogami, Kazutaka Aonuma
No abstract text is available yet for this article.
June 21, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28626989/electrical-isolation-of-the-left-atrial-appendage-by-maze-like-catheter-substrate-modification-a-reproducible-strategy-for-pulmonary-vein-isolation-non-responders
#5
Stefano Bordignon, Laura Perrotta, Daniela Dugo, Fabrizio Bologna, Takahiko Nagase, Alexander Fuernkranz, Kr Julian Chun, Boris Schmidt
INTRODUCTION: The ablation strategy for atrial fibrillation (AF) despite pulmonary vein isolation (PVI) is controversial. Left atrial appendage isolation (LAAI) may contribute to improve outcome. We describe an ablation approach ("Maze-like"-LAAI) that (1) modifies the underlying LA substrate by linear ablation (2) eliminates the LAA as a putative AF trigger site and (3) incorporates an unambiguous procedural endpoint. The role of LAA closure (LAAC) after LAAI was investigated. METHODS: Patients with atrial tachyarrhythmias non-responsive to PVI underwent a LAAI ablation procedure...
June 19, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28608980/safety-and-feasibility-of-percutaneous-skin-closure-using-purse-string-suture-compared-with-compression-bandage-after-pulmonary-vein-isolation
#6
Ersan Akkaya, Alexander Berkowitsch, Sergej Zaltsberg, Nikolas Deubner, Harald Greiss, Andreas Hain, Christian W Hamm, Johannes Sperzel, Thomas Neumann, Malte Kuniss
INTRODUCTION: This observational study was designed to analyze the safety and feasibility of percutaneous skin closure using a purse-string suture and compare it with the use of a compression bandage after pulmonary vein isolation. METHODS AND RESULTS: A total of 407 patients undergoing pulmonary vein isolation (217 with radiofrequency and 190 with cryoballoon ablation) were treated with either purse-string sutures or compression bandages. The purse-string suture was applied after ablation before withdrawal of the sheaths...
June 13, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28608977/treating-cardiac-dysrhythmias-by-targeting-the-neck-off-target-or-on-the-right-track
#7
EDITORIAL
Marat Fudim, Jonathan P Piccini
No abstract text is available yet for this article.
June 13, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28603943/tachycardia-dependent-brugada-phenocopy-due-to-hyperkalemia
#8
Raed Abu Shama, Antoni Bayes de Luna, Adrian Baranchuk
No abstract text is available yet for this article.
June 12, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28603904/myths-and-legends-of-right-ventricular-septal-pacing
#9
EDITORIAL
Jo-Jo Hai, Hung-Fat Tse
No abstract text is available yet for this article.
June 12, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28597532/substrate-characterization-and-catheter-ablation-in-patients-with-scar-related-ventricular-tachycardia-using-ultra-high-density-3d-mapping
#10
Jana M Nührich, Lukas Kaiser, Ruken Özge Akbulak, Benjamin N Schäffer, Christian Eickholt, Michael Schwarzl, Pawel Kuklik, Julia Moser, Mario Jularic, Stephan Willems, Christian Meyer
BACKGROUND: Ablation of scar-related ventricular tachycardia (VT), especially in non-inducible VT or hemodynamically unstable patients, can be challenging. Thus, we evaluated feasibility of an ultra high-density 3D-mapping approach to characterize the ventricular substrate and, if possible, to map VT. METHODS AND RESULTS: Twenty-two patients (67±2 years, mean LV-EF 36±3%) with both ischemic and non-ischemic cardiomyopathy and documented VT underwent mapping and catheter ablation using a 64-electrode mini-basket catheter...
June 8, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28570022/slow-antegrade-excitation-and-delayed-retrograde-activation-through-an-inexcitable-zone-a-basis-for-arrhythmia-formation-in-infarcted-myocardium-ex-vivo
#11
Eugene Patterson, Benjamin J Scherlag
INTRODUCTION: The electrophysiologic mechanism for rate-dependent PVBs associated with double potentials (DPs) was investigated in infarcted canine hearts using bipolar and intracellular microelectrode recordings. METHODS AND RESULTS: Dogs exhibiting rate-related ventricular ectopic beats (coupling interval, 390 ± 54 milliseconds) during sinus rhythm or atrial pacing were studied 4-5 days (N = 63) or 25 days (N = 16) following anterior descending coronary artery ligation...
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28570019/clinical-assessment-of-cryoballoon-ablation-in-cases-with-atrial-fibrillation-and-a-left-common-pulmonary-vein
#12
Takatoshi Shigeta, Kaoru Okishige, Yasuteru Yamauchi, Hideshi Aoyagi, Tomofumi Nakamura, Mitsumi Yamashita, Takuro Nishimura, Naruhiko Ito, Yusuke Tsuchiya, Mitsutoshi Asano, Tsukasa Shimura, Hidetoshi Suzuki, Manabu Kurabayashi, Takehiko Keida, Tetsuo Sasano, Kenzo Hirao
INTRODUCTION: Pulmonary vein isolation (PVI) using a cryoballoon (CB) is a useful tool for treating atrial fibrillation (AF); however, the clinical efficacy of the CB has never been fully investigated in patients with a left common pulmonary vein (LCPV). METHODS AND RESULTS: Three hundred twenty-four consecutive paroxysmal AF patients underwent PVI with a CB. Three-dimensional computed tomography was performed in all patients before the ablation. The clinical outcomes of the AF ablation between patients with (Group A) and without an LCPV (Group B) were compared...
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28569440/small-reentry-in-a-mega-coronary-sinus-anatomical-and-high-density-activation-mapping
#13
Hussam Ali, Sara Foresti, Riccardo Cappato
No abstract text is available yet for this article.
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28569435/the-new-kids-on-the-block-of-arrhythmogenic-disorders-short-qt-syndrome-and-early-repolarization
#14
REVIEW
Andrea Mazzanti, Katherine Underwood, Dmitriy Nevelev, Shanna Kofman, Silvia G Priori
Short QT Syndrome (SQTS) is a one of the rarest inheritable cardiac channelopathy, characterized by an accelerated cardiac repolarization, which is also the substrate for the development of life-threatening ventricular arrhythmias. Up to this date, fewer than 200 SQTS cases have been reported in the literature worldwide. Patients with SQTS may experience a cardiac arrest as early as in the neonatal period or as late as 80 years old. The cumulative probability of experiencing a cardiac arrest by the fifth decade of life approaches 40%, highlighting the importance of early recognition and management...
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28569424/single-incision-percutaneous-pericardial-icd-lead-placement-in-a-piglet-model
#15
Bradley C Clark, Justin D Opfermann, Tanya D Davis, Axel Krieger, Charles I Berul
INTRODUCTION: Our group has demonstrated the feasibility of percutaneous pericardial ICD lead placement in a piglet model utilizing direct visualization from a lateral thoracoscopic approach. Development of a novel delivery tool that incorporates visualization allows for the procedure to be performed with a 1 cm subxiphoid incision. METHODS AND RESULTS: A 1 cm incision is made in the subxiphoid area and a novel self-anchoring delivery tool is inserted. A rigid thoracoscope and needle are inserted into two crossed working channels of the tool...
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28569422/role-of-contact-force-guided-radiofrequency-catheter-ablation-for-treatment-of-atrial-fibrillation-a-systematic-review-and-meta-analysis
#16
Hui Lin, Yi-He Chen, Jian-Wen Hou, Zhao-Yang Lu, Yin Xiang, Yi-Gang Li
INTRODUCTION: CF-sensing catheter emerged as a novel ablation technology and was increasingly used in clinical practice. Nonetheless, available evidence of efficacy and safety comparison between CF-guided RF catheter ablation and non-CF-guided ablation for treatment of AF was still lacking. METHODS AND RESULTS: Twenty-two eligible studies were included after systematic review through the MEDLINE, Google Scholar, the Cochrane Library and PubMed databases. AF/atrial tachycardia-free survival was markedly improved in CF-guided catheter ablation compared with non-CF-guided ablation at a median 12-month follow-up (RR: 1...
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28569421/autonomic-nervous-system-modulation-and-clinical-outcome-after-pulmonary-vein-isolation-using-the-second-generation-cryoballoon
#17
Shinsuke Miyazaki, Hiroaki Nakamura, Hiroshi Taniguchi, Hitoshi Hachiya, Takatsugu Kajiyama, Tomonori Watanabe, Miyako Igarashi, Sadamitsu Ichijo, Kenzo Hirao, Yoshito Iesaka
BACKGROUND: The intrinsic cardiac autonomic nervous system (ANS) plays a significant role in atrial fibrillation (AF) mechanisms. This study evaluated the incidence and impact of intraprocedural vagal reactions and ANS modulation by pulmonary vein isolation (PVI) using second-generation cryoballoons on outcomes. METHODS: One hundred three paroxysmal AF patients underwent PVI with one 28-mm second-generation balloon. The median follow-up was 15.0 (12.0-18.0) months...
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28569383/atrial-fibrillation-cognition-and-dementia-a-review
#18
REVIEW
Summer Aldrugh, Mayank Sardana, Nils Henninger, Jane S Saczynski, David D McManus
Atrial fibrillation (AF) is one of the most common types of cardiac arrhythmia, particularly among older adults. AF confers a 5-fold risk for thromboembolic stroke as well as a 2-fold higher risk for congestive heart failure, morbidity, and mortality. Although stroke remains an important and impactful complication of AF, recent studies have shown that AF is independently associated with other neurological disorders, including cognitive impairment and dementia, even after adjusting for prior ischemic stroke...
June 1, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28544109/express-with-caution-epitope-tags-and-cdna-variants-effects-on-herg-channel-trafficking-half-life-and-function
#19
Marika L Osterbur Badhey, Alexander C Bertalovitz, Thomas V McDonald
INTRODUCTION: Genetic mutations in KCNH2, which encodes hERG, the alpha subunit of the potassium channel responsible for the IKr current, cause long QT syndrome (LQTS), an inherited cardiac arrhythmia disorder. Electrophysiology techniques are used to correlate genotype with molecular phenotype to determine which mutations identified in patients diagnosed with LQTS are disease causing, and which are benign. These investigations are usually done using heterologous expression in cell lines, and often, epitope fusion tags are used to enable isolation and identification of the protein of interest...
May 24, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28543955/percutaneous-trans-hepatic-route-for-dual-chamber-pacemaker-implantation-in-a-patient-with-post-glenn-operation
#20
Jiafu Wei, Ying Xu, Yuan Fang
No abstract text is available yet for this article.
May 24, 2017: Journal of Cardiovascular Electrophysiology
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