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Journal of Cardiovascular Electrophysiology

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https://www.readbyqxmd.com/read/28497899/replacing-warfarin-with-a-novel-oral-anticoagulant-risk-of-recurrent-bleeding-and-stroke-in-patients-with-warfarin-ineligible-or-failure-in-patients-with-atrial-fibrillation-the-roar-study
#1
Mohit K Turagam, Valay Parikh, Muhammad R Afzal, Rakesh Gopinnathanair, Madhav Lavu, Arun Kanmanthareddy, Jayasree Pillarisetti, Madhu Reddy, Donita Atkins, Sudharani Bommana, Melissa Jaeger, Courtney Jeffery, Sanghamitra Mohanty, Pasquale Santangeli, Jie Cheng, Luigi Dibiase, Calambur Narasimhan, Andrea Natale, Dhanunjaya Lakkireddy
BACKGROUND: A significant proportion of patients treated with warfarin for atrial fibrillation (AF) become warfarin ineligible (WI) due to major bleeding events (MBE) or systemic thromboembolism (STE). We report a large multicenter real-world experience of the use of DOACs in these WI patients. METHODS: We report the outcomes of 263 WI patients treated with DOACs. The primary objective was to evaluate clinical outcomes of STE and MBE with DOACs. Secondary objective was to assess clinical predictors of repeat MBE and STE on DOACs...
May 12, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28497857/validation-of-electrical-ostial-pulmonary-vein-isolation-verified-with-a-spiral-inner-lumen-mapping-catheter-during-second-generation-cryoballoon-ablation
#2
Shinsuke Miyazaki, Takatsugu Kajiyama, Tomonori Watanabe, Hiroshi Taniguchi, Hiroaki Nakamura, Rikuta Hamaya, Shigeki Kusa, Miyako Igarashi, Hitoshi Hachiya, Kenzo Hirao, Yoshito Iesaka
BACKGROUND: Achieve catheters are cryoballoon guidewires that enable pulmonary vein (PV) potential mapping. The single catheter approach in conjunction with the Achieve catheter is currently standard practice in second-generation cryoballoon ablation, yet circumferential mapping catheters are the gold standard for evaluating PV isolation (PVI). The study sought to validate the ostial PVI verified by an Achieve catheter alone. METHODS: One-hundred fifty-one paroxysmal atrial fibrillation patients undergoing PVI using exclusively 28-mm second-generation cryoballoons were enrolled...
May 12, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28485545/substrate-dependent-risk-stratification-for-implantable-cardioverter-defibrillator-therapies-using-cardiac-magnetic-resonance-imaging-the-importance-of-t1-mapping-in-non-ischemic-patients
#3
Simon Claridge, Silvia Mennuni, Thomas Jackson, Jonathan M Behar, Bradley Porter, Benjamin Sieniewicz, Julian Bostock, Mark O'Neill, Francis Murgatroyd, Jaswinder Gill, Gerald Carr-White, Amedeo Chiribiri, Reza Razavi, Zhong Chen, Christopher Aldo Rinaldi
INTRODUCTION: The role of implantable cardioverter defibrillators in non-ischemic cardiomyopathy is unclear and better risk-stratification is required. We sought to determine if T1 mapping predicts appropriate defibrillator therapy in patients with non-ischemic cardiomyopathy. We studied a mixed cohort of ischemic and non-ischemic patients to determine whether different CMR applications (T1 mapping, late gadolinium enhancement and Grayzone) were selectively predictive of therapies for the different arrhythmic substrates...
May 9, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28485517/selectivity-who-really-should-be-offered-af-ablations
#4
EDITORIAL
Jane Chen
No abstract text is available yet for this article.
May 9, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28485513/first-description-of-a-double-wall-balloon-breach-during-cryoballoon-ablation-for-atrial-fibrillation
#5
Keith Suarez, Javier Banchs, Hae W Lim, James N Black
Balloon breach during cryoablation: To date, this is the first published report of a double-wall breach while using the cryoballoon ablation catheter during the treatment of a patient with atrial fibrillation; however, there have been previous balloon breaches in both the second and third-generation cryoballoon ablation catheter usage. In this report, we describe the case of a double-wall balloon breach and the intraoperative care that was necessary to stabilize the patient. Additionally, we review other known cases of double-wall balloon breaches, and we examine the safety systems of the cryoballoon catheter that mitigate some of the potential patient complications...
May 9, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28485510/longstanding-persistent-accelerated-idioatrial-rhythm-benign-sinus-node-like-rhythm-or-insidious-rhythm
#6
Hailei Liu, Chao Zhu, Bing Yang, Weizhu Ju, Hongwu Chen, Fengxiang Zhang, Kai Gu, Mingfang Li, Pipin Kojodjojo, Minglong Chen
INTRODUCTION: Detailed description of longstanding persistent accelerated idioatrial rhythm (AIAR) is lacking. This observational study investigated the clinical manifestations, electrophysiological characteristics, diagnosis, treatment and prognosis of this unusual arrhythmia. METHODS AND RESULTS: Fifteen patients (11 males; average age 25.9±15.7 years) suspected with longstanding persistent AIAR were enrolled in our study. All patients had ECG, 24-hour Holter monitoring, isoproterenol provocation test, echocardiogram, and exercise treadmill test...
May 9, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28471545/eleven-year-trends-of-inpatient-pacemaker-implantation-in-patients-diagnosed-with-sick-sinus-syndrome
#7
Avirup Guha, Xiao Xiang, Devin Haddad, Benjamin Buck, Xu Gao, Michael Dunleavy, Ellen Liu, Dilesh Patel, Vadim V Fedorov, Emile G Daoud
BACKGROUND: Pacemakers (PM) are used for managing sick sinus syndrome (SSS). This study evaluates predictors and trends of PM implantation for SSS. METHODS: Patients were identified from the National Inpatient Sample dataset (2003-13). Included patients were ≥18 years old, had a diagnosis of sinus node dysfunction and atrial arrhythmia (i.e., SSS). Patients who died, transferred out, who had prior device or had a defibrillator or resynchronization therapy device implanted were excluded...
May 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28471068/stellate-ganglion-blockade-and-bilateral-cardiac-sympathetic-denervation-in-patients-with-life-threatening-ventricular-arrhythmias
#8
Ricardo Cardona-Guarache, Santosh K Padala, Luis Velazco-Davila, Anthony Cassano, Antonio Abbate, Kenneth A Ellenbogen, Jayanthi Koneru
Autonomic modulation is being increasingly employed as a strategy to treat ventricular arrhythmias refractory to beta-blockers, antiarrhythmic drugs and catheter-based ablation procedures. We report 6 patients with refractory ventricular tachycardia (VT) or ventricular fibrillation (VF) treated with stellate ganglion blockade (SGB) and/or bilateral cardiac sympathetic denervation (CSD). Our case series emphasizes the concept that the cardiac sympathetic nerves are important targets in the management of ventricular arrhythmias...
May 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28471039/catheter-ablation-of-pulmonary-sinus-cusp-derived-ventricular-arrhythmias-by-the-reversed-u-curve-technique
#9
EDITORIAL
Christian-Hendrik Heeger, Karl-Heinz Kuck, Feifan Ouyang
No abstract text is available yet for this article.
May 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28471019/type-and-rate-of-atrial-fibrillation-termination-due-to-rotational-activity-ablation-combined-with-pulmonary-vein-isolation
#10
Zsuzsanna Kis, Dominic A Theuns, Rohit Bhagwandien, Sip Wijchers, Sing-Chien Yap, Tamas Szili-Torok
BACKGROUND: There remains controversy about the optimal ablation technique and termination rate of atrial fibrillation (AF) during catheter ablation in patients with persistent AF. The aim of this study was to determine the rate and timing of AF termination during combined pulmonary vein isolation (PVI) and focal impulse and rotor modulation (FIRM)-guided ablation of rotational activity (RoAc). METHODS: This single-center, prospective cohort study enrolled 38 consecutive patients (63% male, mean age 63 ± 11 years) with persistent AF (mean left atrial size: 46 ± 7 mm), who underwent FIRM mapping and ablation of the identified RoAcs followed by PVI...
May 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28471012/effects-of-epicardial-versus-transvenous-left-ventricular-lead-placement-on-left-ventricular-function-and-cardiac-perfusion-in-cardiac-resynchronisation-therapy-a-randomized-clinical-trial
#11
Vincent F van Dijk, Jim Fanggiday, Jippe C Balt, Maurits C E F Wijffels, Edgar J Daeter, J C Kelder, Lucas V A Boersma
INTRODUCTION: Optimal left ventricular (LV) lead position in patients undergoing cardiac resynchronization therapy(CRT) is crucial to achieve an optimal effect on hemodynamics. Due to various difficulties, up to 30% of transvenous LV lead placements fail, or a suboptimal position is achieved. Surgical epicardial LV lead placement could be performed at a position anticipated to be the optimal site. This could have a more favorable effect, which may be expressed by increased improvement in left ventricular ejection fraction(LVEF) and cardiac perfusion...
May 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28470984/application-of-the-2015-acc-aha-hrs-guidelines-for-risk-stratification-for-sudden-death-in-adult-patients-with-asymptomatic-pre-excitation
#12
Manoj N Obeyesekere, George J Klein
The management of the asymptomatic pre-excited patient largely hinges on risk stratification and individual patient considerations and choice. A high threshold to treat patients may lead to a small overall risk of death while a low threshold clearly leads to increased invasive testing and ablation with associated cost and procedural risk. A firm recommendation to uniformly assess all by electrophysiology study or, alternatively, reassure all is inappropriate and unjustified by data as reflected in the recent guideline recommendations...
May 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28470974/v-a-when-the-paradigm-fails
#13
Giuseppe Picciolo, Pasquale Crea, Francesco Luzza, Giuseppe Oreto
No abstract text is available yet for this article.
May 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28467672/treatment-of-pulmonary-sinus-cusp-derived-ventricular-arrhythmia-with-reversed-u-curve-catheter-ablation
#14
Yufan Yang, Qiming Liu, Zhenjiang Liu, Shenghua Zhou
BACKGROUND: The origin of pulmonary sinus cusp (PSC)-derived ventricular arrhythmia (VA) is a highly specialized anatomical structure; therefore, insertion of the radiofrequency ablation catheter tip to the target site to ensure safe ablation is a major challenge for clinicians. PURPOSE: To summarize ablation methods, and provide valuable experience for the treatment of pulmonary sinus cusp-derived VA with ablation. METHODS: A retrospective analysis and summary of the clinical data of 15 patients undergoing catheter ablation for pulmonary sinus cusp-derived VA in Cardiac Intervention Therapy Center, The Second Xiangya Hospital of Central South University between January 2013 and July 2015 was conducted...
May 3, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28467667/technological-advances-to-improve-the-fidelity-of-maps-created-using-multi-electrode-fast-automated-mapping-to-guide-catheter-ablation-of-atrial-fibrillation
#15
LETTER
Jackson J Liang, Sanjay Dixit
No abstract text is available yet for this article.
May 3, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28467658/bipolar-voltage-analysis-with-multi-electrode-mapping
#16
LETTER
Vivek Chaturvedi, Baptiste Maille, Dhiraj Gupta
No abstract text is available yet for this article.
May 3, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28467653/electrophysiologic-effects-of-adenosine-vs-atp
#17
LETTER
Amir Pelleg
No abstract text is available yet for this article.
May 3, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28467647/prediction-of-optimal-cardiac-resynchronization-by-vectors-extracted-from-electrograms-in-dyssynchronous-canine-hearts
#18
Elien B Engels, Marc Strik, Lars B van Middendorp, Marion Kuiper, Kevin Vernooy, Frits W Prinzen
INTRODUCTION: Proper optimization of atrioventricular (AV) and interventricular (VV) intervals can improve the response to cardiac resynchronization therapy (CRT). It has been demonstrated that the area of the QRS complex (QRSarea) extracted from the vectorcardiogram can be used as a predictor of optimal CRT-device settings. We explored the possibility of extracting vectors from the electrograms (EGMs) obtained from pacing electrodes and of using these EGM-based vectors (EGMVs) to individually optimize acute haemodynamic CRT response...
May 3, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28467627/response-to-letter-to-editor
#19
LETTER
Sandeep Prabhu, Peter M Kistler
No abstract text is available yet for this article.
May 3, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28452189/qt-prolongation-by-dexamphetamine-does-experience-matter
#20
Anouk Schrantee, Lena Václavů, Liesbeth Reneman, Hein J Verberne, Jan Booij, Hanno L Tan
INTRODUCTION: Case reports of life-threatening cardiac arrhythmias and sudden cardiac arrest (SCA) among amphetamine users have raised serious concerns about the cardiac safety of this class of drugs. This is important in light of the high prevalence of dexamphetamine (dAMPH) prescription for attention-deficit/hyperactivity disorder (ADHD), and its rising use as a recreational drug. The objective was to investigate electrocardiogram (ECG) parameters upon intravenous administration of a single dAMPH dose in habitual recreational dAMPH users (users) and healthy gender/age/IQ-matched controls (non-users)...
April 27, 2017: Journal of Cardiovascular Electrophysiology
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