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Cytopathology: Official Journal of the British Society for Clinical Cytology

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https://www.readbyqxmd.com/read/29457294/cytology-of-cerebrospinal-fluid-involvement-in-systemic-anaplastic-large-cell-lymphoma
#1
P Dehuri, C Bhandary, D Gochhait, B H Srinivas, D Basu, N Siddaraju
No abstract text is available yet for this article.
February 19, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29457291/does-sedation-offer-better-outcomes-than-local-anaesthesia-for-thyroid-fna-in-adult-patients
#2
R M Kholmatov, H S Khadra, F Murad, T M Ahmed, A B Sholl, E Kandil
OBJECTIVE: To examine the potential benefits of sedation in adults undergoing fine needle aspiration (FNA) of thyroid nodules. METHODS: This retrospective study compared the outcomes of sedated and non-sedated FNA patients. RESULTS: A total of 860 patients underwent 1698 FNAs of thyroid nodules. The mean patient age was 52.4±14.4 years, and 80.2% of patients were women. The non-sedated group consisted of 782 patients with 1543 (93.5%) FNA procedures...
February 18, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29405522/fna-of-peri-implant-seroma-of-the-breast
#3
J Hatem, J D Tobey, M P Solomon, G H Yu
No abstract text is available yet for this article.
February 6, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29388266/adenocarcinoma-predominant-pattern-subtyping-and-nuclear-grading-in-cytology-is-there-a-role-in-prognostication-of-advanced-pulmonary-adenocarcinomas
#4
A Nambirajan, H Kaur, K Jangra, K Kaur, K Madan, S R Mathur, V K Iyer, D Jain
INTRODUCTION: Primary lung adenocarcinomas (ADs) show varied architectural patterns, and pattern-based subtyping of ADs is currently recommended due to prognostic implications. Predicting AD patterns on cytology is challenging; however, cytological nuclear features appear to correlate with histological grade and survival in early stage lung ADs. The feasibility and value of AD pattern prediction and nuclear grading on cytology in advanced lung ADs is not known. We aimed to predict patterns and analyse nuclear features on cytology and evaluate their role in prognostication...
February 1, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29363841/a-combined-test-using-both-cell-sediment-and-supernatant-cell-free-dna-in-pleural-effusion-shows-increased-sensitivity-in-detecting-activating-egfr-mutation-in-lung-cancer-patients
#5
A Kawahara, C Fukumitsu, K Azuma, T Taira, H Abe, Y Takase, K Murata, E Sadashima, S Hattori, Y Naito, J Akiba
INTRODUCTION: The aim of this study was to examine whether a combined test using both cell sediment and supernatant cytology cell-free DNA (ccfDNA) is more useful in detecting EGFR mutation than using cell sediment DNA or supernatant ccfDNA alone in pleural effusion of lung cancer patients. METHODS: A total of 74 lung adenocarcinoma patients with paired samples between primary tumour and corresponding metastatic tumour with both cell sediment and supernatant ccfDNA of pleural effusion cytology were enrolled in this study...
January 24, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29350424/prevalence-of-high-grade-cervical-intraepithelial-neoplasia-in-women-with-persistent-high-risk-hpv-genotypes-and-negative-cytology
#6
M Macdonald, J Crossley, K Ellis, N Dudding, R Lyon, J H F Smith, J A Tidy, J E Palmer
INTRODUCTION: Primary HPV screening will be implemented into the English Cervical Screening Programme by 2019. Its impact upon women referred to colposcopy, with negative cytology but persistently positive high-risk HPV (hrHPV), remains unreported from UK Sentinel sites. HPV primary screening was introduced in Sheffield, UK in April 2013; this paper reports its impact on the service. METHODS: A retrospective cohort study was performed from June 2014 to July 2016 at the Jessop Wing Colposcopy Unit, Sheffield...
January 19, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29280216/contribution-of-cervical-cytology-in-the-diagnostic-work-up-of-patients-with-endometrial-cancer
#7
L C M Amkreutz, J M A Pijnenborg, D W L Joosten, H J M M Mertens, S M J Van Kuijk, M J A Engelen, M Bergmans, W E Nolting, R F P M Kruitwagen
INTRODUCTION: Abnormal cervical cytology in patients with endometrial cancer (EC) has been associated with poor outcome. The aim of this study was to evaluate whether cervical cytology could contribute to an improved preoperative identification of high-grade EC (serous, clear cell, carcinosarcoma, high-grade endometrioid EC) in final histology. METHODS: A retrospective cohort study was performed in five hospitals in the Netherlands. A total of 554 patients with EC that underwent primary surgical treatment between 2002 and 2010 were included...
December 27, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29280203/improving-the-cytological-diagnosis-of-high-grade-serous-carcinoma-in-ascites-with-a-panel-of-complementary-biomarkers-in-cell-blocks
#8
X Zhang, L Chen, Y Liu, Y Xu, X Zhang, Y Shi, C Wang, P L Zhang, Y Liu
INTRODUCTION: Precise cytological diagnosis of pelvic high-grade serous carcinoma (HGSC) in ascites is important for tumour staging, therapeutic decision-making and prognostic evaluation. However, it can often be difficult to distinguish metastatic HGSC cells from reactive mesothelial cells based on morphology alone. Immunocytochemical analysis of ascites cell blocks has been used to obtain accurate diagnosis and provide a reliable basis for treatment decisions in the clinic. This study was performed to determine whether a panel of antibodies is necessary to achieve high specificity and sensitivity for the identification of HGSC cells...
December 27, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29251368/the-paris-system-for-urine-cytology-in-upper-tract-urothelial-specimens-a-comparative-analysis-with-biopsy-and-surgical-resection
#9
X Zheng, Q Si, D Du, M Harshan, Z Zhang, K Haines, W Shi, D C Chhieng
INTRODUCTION: The Paris System (TPS) has recently been used in classification of urinary tract cytological specimens. Upper urinary tract (UUT) specimens are cytologically challenging. The utility of TPS was investigated in evaluating UUT specimens and its correlation with subsequent histological follow-up. METHOD: From 2014 to 2017, 324 cytology cases of UUT from 179 patients were retrieved. Concurrent or subsequent biopsy or resection within a 2-month period was available in 125 cases from 74 patients...
December 18, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29251367/thyroid-fna-diagnostics-in-a-real-life-setting-experiences-of-the-implementation-of-the-bethesda-system-in-finland
#10
I Paajanen, S Metso, P Jaatinen, I Kholová
INTRODUCTION: The Bethesda system is widely accepted for thyroid FNA diagnostics, but has scarcely been analysed in relation to clinical background data. Our aim was to analyse the thyroid FNA diagnostic process in view of clinical data, and to assess the validity of the Bethesda system during the first year of implementation. METHODS: There were 415 thyroid FNAs taken from 363 patients during October 2011-September 2012 in the Pirkanmaa Hospital District, Finland...
December 18, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29218750/pelvic-lymphangioleiomyomatosis-diagnosed-by-fna-of-cyst-fluid
#11
LETTER
S T Gokaslan, K S Carrick
No abstract text is available yet for this article.
December 8, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29207443/carcinoid-tumour-of-soft-tissue-primary-or-metastasis
#12
D Gochhait, S Umamahesweran, P Dehuri, P C Toi, R Govindarajalou, M Ponnusamy
No abstract text is available yet for this article.
December 5, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29205596/detection-and-analysis-of-abnormal-nuclear-changes-in-oral-cytological-smears-by-papanicolaou-staining
#13
LETTER
R Nag, H Raza, S Kumar, R Seal, A Banerjee, R R Paul, M Pal, J Chatterjee, R K Das
No abstract text is available yet for this article.
December 5, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29205587/the-impact-of-repeat-fna-in-non-diagnostic-and-indeterminate-thyroid-nodules-a-5-year-single-centre-experience
#14
M A Saieg, B Barbosa, J Nishi, A Ferrari, F Costa
INTRODUCTION: FNA is a well-established method for the preoperative diagnosis of thyroid nodules, but limitations still reside among non-diagnostic and indeterminate samples. The objective of the present study was to assess the impact of repeat FNA in thyroid nodules primarily classified as non-diagnostic and indeterminate, with the evaluation of the diagnostic resolution rate after the reassessment of the nodule. METHODS: We retrospectively collected all cases of thyroid FNA at our institution in the last 5 years that had one or more repeat aspirations of the same nodule, calculating the percentage of samples with change in the diagnostic category...
December 4, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29193477/outcomes-of-endoscopic-ultrasound-guided-pancreatic-fnac-diagnosis-for-solid-and-cystic-lesions-at-manchester-royal-infirmary-based-upon-the-papanicolaou-society-of-cytopathology-pancreaticobiliary-terminology-classification-scheme
#15
P K Wright, D A Shelton, M R Holbrook, S A Thiryayi, N Narine, D Slater, D N Rana
OBJECTIVE: To compare endoscopic ultrasound (EUS)-FNAC diagnosis of pancreatic lesions with patient outcome based upon the Papanicolaou Society of Cytopathology pancreaticobiliary terminology classification scheme diagnostic categories: Panc 1 (non-diagnostic); Panc 2 (negative for malignancy/neoplasia); Panc 3 (atypical); Panc 4B (neoplastic, benign); Panc 4O (neoplastic, other); Panc 5 (suspicious of malignancy); and Panc 6 (positive/malignant). METHODS: All EUS-FNA pancreas specimens taken at Manchester Royal Infirmary in 2015 were prospectively classified according to the above scheme at the time of cytology reporting and data recorded prospectively...
November 29, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29193452/finnish-cytotechnologists-views-on-the-competencies-of-newly-graduated-biomedical-scientists-in-clinical-cytology
#16
E Liikanen
OBJECTIVE: This study asked 40 cytotechnologists for their views on the competencies of newly graduated biomedical scientists in clinical cytology during the national conference of the Finnish Association of Cytotechnologists in November 2015. METHODS: The questionnaire mainly consisted of statements that were scored on a five-point Likert-scale, where 1 was not important and 5 was very important. It covered five sections of clinical cytology: sampling and techniques, gynaecological screening, non-gynaecological screening, safety and quality management, and miscellaneous...
November 29, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29165889/rosettes-in-papillary-carcinoma-of-thyroid-a-rare-cytomorphological-indicator-of-aggressive-variants
#17
LETTER
A Nambirajan, S Batool, P Mandal, T Nakra, S Agarwal, D Jain
No abstract text is available yet for this article.
December 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29165888/molecular-pathology-and-thyroid-fna
#18
REVIEW
D N Poller, S Glaysher
This review summarises molecular pathological techniques applicable to thyroid FNA. The molecular pathology of thyroid tumours is now fairly well understood. Molecular methods may be used as a rule-in test for diagnosis of malignancy in thyroid nodules, eg BRAF V600E point mutation, use of a seven-gene mutational panel (BRAF V600E, RAS genes, RET/PTC or PAX8/PPARG rearrangement), or as a comprehensive multigene next-generation sequencing panel, eg ThyroSeq v2. Molecular methods can also be applied as rule-out tests for malignancy in thyroid nodules, eg Afirma or ThyroSeq v2 or as markers of prognosis, eg TERT promoter mutation or other gene mutations including BRAF V600E, TP53 and AKT1, and as tests for newly defined tumour entities such as non-invasive follicular thyroid neoplasm with papillary like nuclei, or as a molecular marker(s) for targeted therapies...
December 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29165887/this-month-s-cytopathology
#19
EDITORIAL
D N Poller
No abstract text is available yet for this article.
December 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29165886/pre-operative-features-of-non-invasive-follicular-thyroid-neoplasms-with-papillary-like-nuclear-features-an-analysis-of-their-cytological-gene-expression-classifier-and-sonographic-findings
#20
S J Song, V A LiVolsi, K Montone, Z Baloch
OBJECTIVE: To investigate the corresponding cytological diagnoses, Gene Expression Classifier (GEC) results and ultrasound features of thyroid nodules diagnosed as non-invasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP), as well as any coexisting pathology. METHODS: We performed a retrospective review of thyroid nodules histologically diagnosed as NIFTP at our institution between 1st April 2016 and 1st April 2017. The following data points were collected: demographics, nodule size, ultrasound features, cytological diagnosis, GEC results, origin of sample (in-house vs outside hospital) and any additional pathology identified in the resection specimen...
December 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
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