Milagros Fanny Vera Castro, Charles Elias Assmann, Karine Paula Reichert, Priscila Marquezan Coppetti, Naiara Stefanello, Aniélen Dutra da Silva, Vitor Bastianello Mostardeiro, Loren Borba de Jesus, Marcylene Vieira da Silveira, Adriel Antonio Schirmann, Mateus Fracasso, Roberto Marinho Maciel, Vera Maria Melchiors Morsch, Maria Rosa Chitolina Schetinger
This study evaluated the effect of vitamin D3 (VIT D3 ) supplementation on the enzymatic activities and density of ectonucleoside triphosphate diphosphohydrolase (E-NTPDase), ecto-5-nucleotidase (E-5'-NT), adenosine deaminase (ADA), as well as the density of P2 × 7R, P2Y12R, A1R, A2AR receptors, IL-1β, and oxidative parameters in type 2 diabetic rats. Forty male Wistar rats were fed a high carbohydrate-high fat diet (HCHFD) and received an intraperitoneal injection containing a single dose of streptozotocin (STZ, 35 mg/kg)...
February 17, 2024: Journal of Nutritional Biochemistry