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International Psychogeriatrics

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https://www.readbyqxmd.com/read/30426918/a-clinically-translatable-machine-learning-algorithm-for-the-prediction-of-alzheimer-s-disease-conversion-further-evidence-of-its-accuracy-via-a-transfer-learning-approach
#1
Massimiliano Grassi, David A Loewenstein, Daniela Caldirola, Koen Schruers, Ranjan Duara, Giampaolo Perna
ABSTRACTBackground:In a previous study, we developed a highly performant and clinically-translatable machine learning algorithm for a prediction of three-year conversion to Alzheimer's disease (AD) in subjects with Mild Cognitive Impairment (MCI) and Pre-mild Cognitive Impairment. Further tests are necessary to demonstrate its accuracy when applied to subjects not used in the original training process. In this study, we aimed to provide preliminary evidence of this via a transfer learning approach. METHODS: We initially employed the same baseline information (i...
November 14, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30426917/loneliness-interacts-with-family-relationship-in-relation-to-cognitive-function-in-chinese-older-adults
#2
Ada W T Fung, Allen T C Lee, S-T Cheng, Linda C W Lam
ABSTRACTObjectives:Loneliness and social networks have been extensively studied in relation to cognitive impairments, but how they interact with each other in relation to cognition is still unclear. This study aimed at exploring the interaction of loneliness and various types of social networks in relation to cognition in older adults. DESIGN: a cross-sectional study. SETTING: face-to-face interview. PARTICIPANTS: 497 older adults with normal global cognition were interviewed...
November 14, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30426911/is-the-montreal-cognitive-assessment-moca-screening-superior-to-the-mini-mental-state-examination-mmse-in-the-detection-of-mild-cognitive-impairment-mci-and-alzheimer-s-disease-ad-in-the-elderly
#3
Tiago C C Pinto, Leonardo Machado, Tatiana M Bulgacov, Antônio L Rodrigues-Júnior, Maria L G Costa, Rosana C C Ximenes, Everton B Sougey
ABSTRACTObjective:To compare the accuracy of Mini-Mental State Examination (MMSE) and of the Montreal Cognitive Assessment (MoCA) in tracking mild cognitive impairment (MCI) and Alzheimer's Disease (AD). METHOD: A Systematic review of the PubMed, Bireme, Science Direct, Cochrane Library, and PsycInfo databases was conducted. Using inclusion and exclusion criteria and staring with 1,629 articles, 34 articles were selected. The quality of the selected research was evaluated through the Quality Assessment of Diagnostic Accuracy Studies 2 tool (QUADAS-2)...
November 14, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30421697/patterns-of-depressive-symptoms-among-younger-elderly-60-74-years-old-and-older-elderly-%C3%A2-75-years-old-in-jamaica
#4
Roger C Gibson, Kenneth James, Norman K Waldron, Wendel D Abel, Denise Eldemire-Shearer, Kathryn Mitchell-Fearon
ABSTRACTObjectives:We sought to explore factors associated with depressive symptom severity among older persons (≥60 years of age) and to compare the depressive symptoms commonly experienced by older elderly (≥75 years) with those commonly experienced by younger elderly (<75 years). DESIGN: Secondary analysis was conducted on data from a nationally representative survey. SETTING: Four parishes in Jamaica. PARTICIPANTS: A total of 2,943 older community dwellers participated...
November 13, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30421692/the-impact-of-frailty-and-cognitive-impairment-on-quality-of-life-employment-and-social-context-matter
#5
Judith Godin, Joshua J Armstrong, Lindsay Wallace, Kenneth Rockwood, Melissa K Andrew
ABSTRACTBackground:How cognitive impairment and frailty combine to impact on older adults' Quality of Life (QoL) is little studied, but their inter-relationships are important given how often they co-occur. We sought to examine how frailty and cognitive impairment, as well as changes in frailty and cognition, are associated with QoL and how these relationships differ based on employment status and social circumstances. METHODS: Using the Survey of Health, Ageing, and Retirement in Europe data, we employed moderated regression, followed by simple slopes analysis, to examine how the relationships between levels of health (i...
November 13, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30421691/a-systematic-review-and-meta-analysis-of-the-prevalence-and-associations-of-stress-and-burnout-among-staff-in-long-term-care-facilities-for-people-with-dementia
#6
Harry Costello, Sebastian Walsh, Claudia Cooper, Gill Livingston
ABSTRACTBackground:Care home staff stress and burnout may be related to high turnover and associated with poorer quality care. We systematically reviewed and meta-analyzed studies reporting stress and burnout and associated factors in staff for people living with dementia in long-term care. METHODS: We searched MEDLINE, PsycINFO, Web of Science databases, and CINAHL database from January 2009 to August 2017. Two raters independently rated study validity using standardized criteria. We meta-analyzed burnout scores across comparable studies using a random effects model...
November 13, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30417806/a-meta-analysis-of-low-intensity-cognitive-behavioral-therapy-based-interventions-for-dementia-caregivers
#7
Laura Kaddour, Naoko Kishita, Anthony Schaller
ABSTRACTObjectives:This study aimed to review the effectiveness of low-intensity cognitive behavioral therapy (CBT)-based interventions for informal dementia caregivers when compared to non-active control conditions. DESIGN: Literature searches were conducted in databases of published (PsycINFO, MEDLINE, CINAHL, Scopus) and unpublished (Open Grey, ISRCTN registry, ClinicalTrials.gov, ProQuest) literature. Individual meta-analyses were conducted for each outcome variable. Pooled intervention effect estimates were calculated as Hedge's g using a random-effects model...
November 12, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30398134/association-of-age-with-risk-of-major-depression-among-patients-with-chronic-kidney-disease-over-midlife-a-nationwide-cohort-study-in-taiwan
#8
Shih-Feng Chen, Yu-Huei Chien, Pau-Chung Chen, I-Jen Wang
ABSTRACTBackground:The impact of age on the development of depression among patients with chronic kidney disease (CKD) at stages before dialysis is not well known. We aimed to explore the incidence of major depression among predialysis CKD patients of successively older ages through midlife. METHODS: We conducted a retrospective cohort study using the longitudinal health insurance database 2005 in Taiwan. This study investigated 17,889 predialysis CKD patients who were further categorized into study (i...
November 6, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30398132/perceived-burden-among-caregivers-of-patients-with-frontotemporal-degeneration-in-the-united-states
#9
Lilah M Besser, James E Galvin
ABSTRACTBackground:Frontotemporal degeneration (FTD) dementia often begins before age 60 and predominantly presents as four subtypes with prominent features of language, behavior, cognition, and motor symptoms. The early onset and unique symptoms place a distinct burden on caregivers of individuals with FTD versus other dementia types, such as Alzheimer's disease. This is the first known study to examine the domains of the FTD caregiver burden and the caregiver and patient characteristics associated with these domains...
November 6, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30398127/management-of-visual-hallucinations-in-dementia-and-parkinson-s-disease
#10
Peter Swann, John T O'Brien
ABSTRACTObjectives:Visual hallucinations are a common symptom in dementia and Parkinson's disease and have been associated with greater cognitive and functional decline, but optimal management strategies are unclear. We review the frequency and pathogenesis of visual hallucinations in dementia and Parkinson's disease and examine the evidence base for their management. DESIGN: We undertook a systematic review of the visual hallucinations in dementia, searching studies published between January 1980 and July 2017 using PubMed with the search terms visual hallucinations AND review AND (dementia OR parkinson*)...
November 6, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30375304/a-comprehensive-approach-of-the-determinants-of-use-of-care-in-dementia-the-recaredem-recourse-to-care-in-dementia-cross-sectional-study
#11
Laetitia Rullier, Céline Meillon, Valérie Bergua, Clément Pimouguet, Magali Gonzalez-Colaço Harmand, Catherine Helmer, Karine Pérès, Jean-François Dartigues, Hélène Amieva
ABSTRACTBackground:Given the rate of the undiagnosed cases of dementia and the consequences of inappropriate care, understanding the factors that explain the use of medical and health care in dementia is a critical concern. Our objective was to identify the psychosocial and medical determinants of use of care in dementia. METHODS: The study sample consisted of 308 participants: the persons with dementia (n = 99) selected from three French population-based cohorts (i.e. PAQUID, 3C, AMI), their family caregivers (primary, n = 96, and secondary, n = 51), and their general practitioners (n = 62)...
October 30, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30362933/predicting-progression-in-the-late-onset-frontal-lobe-syndrome
#12
Flora T Gossink, Everard Vijverberg, Welmoed Krudop, Philip Scheltens, Max L Stek, Yolande A L Pijnenburg, Annemiek Dols
ABSTRACTA late onset frontal lobe syndrome (LOF) refers to a clinical syndrome with apathy, disinhibition, or stereotypical behavior arising in middle or late adulthood. Diagnostics are challenging, and both clinicians and patients need reliable predictors of progression to improve clinical guidance. In this longitudinal multicenter and genetically screened prospective study, 137 LOF patients with frontal behavior (FBI score≥11) and/or stereotypical behavior (SRI≥10) were included. Progression was defined as institutionalization, death, or progression of frontal or temporal atrophy at magnetic resonance imaging (MRI) after two years of follow up...
October 26, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30355385/social-support-networks-and-psychological-wellbeing-in-community-dwelling-older-ghanaian-cohorts
#13
Razak M Gyasi, David R Phillips, Kabila Abass
ABSTRACTBackground:Social support networks for older persons have been related to health outcomes including differences in psychological wellbeing (PWB). However, the specifics of this relationship remain unclear especially in sub-Saharan Africa. This study investigates the (1) relationship between aspects of social support and PWB among older persons in Ghana and (2) the extent to which this relationship is moderated by their education levels and locational characteristics. METHOD: The study included 1,200 community-residing individuals aged 50 years and older who participated in an Aging, Health, Psychological Wellbeing and Health-seeking Behavior Study (AHPWHB) conducted between July 2016 and February 2017...
October 25, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30355384/visual-memory-tests-enhance-the-identification-of-amnestic-mci-cases-at-greater-risk-of-alzheimer-s-disease
#14
Javier Oltra-Cucarella, Miriam Sánchez-SanSegundo, Darren M Lipnicki, John D Crawford, Richard B Lipton, Mindy J Katz, Andrea R Zammit, Nikolaos Scarmeas, Efthimios Dardiotis, Mary H Kosmidis, Antonio Guaita, Roberta Vaccaro, Ki Woong Kim, Ji Won Han, Nicole A Kochan, Henry Brodaty, José A Pérez-Vicente, Luis Cabello-Rodríguez, Perminder S Sachdev, Rosario Ferrer-Cascales
ABSTRACTObjectives:To investigate whether amnestic mild cognitive impairment (aMCI) identified with visual memory tests conveys an increased risk of Alzheimer's disease (risk-AD) and if the risk-AD differs from that associated with aMCI based on verbal memory tests. PARTICIPANTS: 4,771 participants aged 70.76 (SD = 6.74, 45.4% females) from five community-based studies, each a member of the international COSMIC consortium and from a different country, were classified as having normal cognition (NC) or one of visual, verbal, or combined (visual and verbal) aMCI using international criteria and followed for an average of 2...
October 25, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30353799/reducing-risk-factors-for-cognitive-decline-through-psychological-interventions-a-pilot-randomized-controlled-trial
#15
Viviana M Wuthrich, Ronald M Rapee, Brian Draper, Henry Brodaty, Lee-Fay Low, Sharon L Naismith
ABSTRACTObjectives:Modifiable factors associated with increased risk of cognitive decline include emotional (anxiety, depression), cognitive (low social and mental stimulation), and health factors (smoking, alcohol use, sedentary lifestyle, obesity). Older adults with anxiety and depression may be at heightened risk due to direct and indirect impacts of emotional distress on cognitive decline. DESIGN: Randomized controlled trialSetting:Community sample attending a university clinic. PARTICIPANTS: 27 participants (female = 20) aged over 65 years (M = 72...
October 24, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30353798/the-most-problematic-symptoms-of-prion-disease-an-analysis-of-carer-experiences
#16
Liz Ford, Peter Rudge, Kathy Robinson, John Collinge, Michele Gorham, Simon Mead
ABSTRACTObjectives:Prion diseases are rare dementias that most commonly occur sporadically, but can be inherited or acquired, and for which there is no cure. We sought to understand which prion disease symptoms are most problematic for carers, to inform the development of outcome measures. DESIGN: Self-completed questionnaire with follow-up of a subset of participants by structured interview. SETTING: A nested study in the UK National Prion Monitoring Cohort, a longitudinal observational study...
October 24, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30353796/poisoning-deaths-among-late-middle-aged-and-older-adults-comparison-between-suicides-and-deaths-of-undetermined-intent
#17
Namkee G Choi, Diana M DiNitto, C Nathan Marti, Bryan Y Choi
ABSTRACTBackground:Given the rapid increase in prescription and illicit drug poisoning deaths in the 50+ age group, we examined precipitating/risk factors and toxicology results associated with poisoning deaths classified as suicides compared to intent-undetermined death (UnD) among decedents aged 50+. METHODS: Data were from the 2005-2015 US National Violent Death Reporting System (N = 15,453). χ2 tests and multinomial logistic regression models were used to compare three groups of decedents: suicide decedent who left a suicide note, suicide decedent who did not leave a note, and UnD cases...
October 24, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30334500/a-systematic-review-of-non-pharmacological-interventions-for-bpsd-in-nursing-home-residents-with-dementia-from-a-perspective-of-ergonomics
#18
Gubing Wang, Armagan Albayrak, Tischa J M van der Cammen
ABSTRACTBackground:Non-pharmacological interventions for Behavioral and Psychological Symptoms of Dementia (BPSD) have been developed; however, a systematic review on the effectiveness of this type of intervention from a perspective of ergonomics is lacking. According to ergonomics, the capabilities of Persons with Dementia (PwD) should be considered in the interventions for the outcomes to be reliable. We aimed to systematically review the non-pharmacological interventions for BPSD in nursing home residents with an additional assessment criterion based on ergonomics, specifically, capability consideration...
October 18, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30322425/correlates-of-sedentary-behavior-in-middle-aged-and-old-age-people-with-mild-cognitive-impairment-a-multinational-study
#19
Davy Vancampfort, Brendon Stubbs, Elvira Lara, Mathieu Vandenbulcke, Nathalie Swinnen, Ai Koyanagi
OBJECTIVE: Despite the benefits of being active for people with mild cognitive impairment (MCI) on cognition and the acknowledgement that MCI is a critical period for intervening to prevent dementia, little is known about the actual sedentary levels in people with MCI. This study investigates correlates of sedentary behavior (SB) in people with MCI. DESIGN: This was a cross-sectional study. SETTING: Data from the World Health Organization's Study on Global Ageing and Adult Health were analyzed...
October 16, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30318026/elderly-latino-community-members-make-an-educational-video-an-academic-community-collaboration-to-promote-memory-evaluations
#20
Judith Neugroschl, Margaret C Sewell, Mari Umpierre, Raquel Rodriguez, Laura Meyers, Stephanie Kranes, Carlos Aldrete, Alma Collazo, Licet Valois, Mary Sano
ABSTRACTObjectives:To develop an educational video to reach elderly Latinos in order to improve understanding and encourage evaluation of cognitive changes by 1) using focus groups to identify dementia knowledge gaps, health communication preferences and trusted advisors for health concerns; 2) collaborating with elderly Latino community members to create a video; and 3) collecting survey data regarding community response to the video. DESIGN: Grounded theory qualitative approach using focus groups; collaborative community based model to create the video and anonymous survey at community screenings...
October 15, 2018: International Psychogeriatrics
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