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International Psychogeriatrics

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https://www.readbyqxmd.com/read/28816110/reduced-beta-amyloid-sensitivity-for-platelet-monocyte-aggregates-in-edta-blood-of-alzheimer-patients
#1
Michaela Defrancesco, Josef Marksteiner, Christian Humpel
Alzheimer´s disease (AD) is a severe neurodegenerative brain disorder characterized by beta-amyloid plaques, Tau pathology, inflammation, neurodegeneration, and cerebrovascular dysfunction. Besides that, alterations in monocytes and platelets have been reported in the blood of Alzheimer patients. In the present study, we measured circulating levels of platelet-monocyte aggregates in EDTA blood of cognitively healthy participants and 40 AD patients, and examined their changes induced by stimulation with beta-amyloid peptides...
August 17, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28805186/improving-the-social-health-of-community-dwelling-older-people-living-with-dementia-through-a-reablement-program
#2
Yun-Hee Jeon, Lindy Clemson, Sharon L Naismith, Loren Mowszowski, Niki McDonagh, Margaret Mackenzie, Caitlin Dawes, Luisa Krein, Sarah L Szanton
Psychological, neurological, and social impairments caused by dementia may limit the person's everyday living and experiences, but their capacity to enjoy a meaningful life is still retained. Increasingly, evidence has been shown the importance of reablement approaches to care in maximizing the older person's independence, health, and well-being through increased engagement in their daily, physical, social, and community activities. However, there is a major knowledge gap in providing reablement for people living with dementia...
August 14, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28803564/international-psychogeriatrics-paper-of-the-year-2016
#3
Nicola T Lautenschlager
Since 2014, the year in which International Psychogeriatrics celebrated 25 years of existence, International Psychogeriatrics has featured a "paper of the month" (POM) category. Chosen by the editorial team which ranks available new International Psychogeriatrics manuscripts from the categories "original research articles" and "reviews," a POM is identified representing high scientific quality and clinical relevance. Each POM is accompanied by a short commentary highlighting its findings and relevance. For the year 2016 this resulted in twelve papers of the month of which nine were original research articles and three were systematic reviews or meta-analyses...
August 14, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28797309/aging-well-on-the-autism-spectrum-the-perspectives-of-autistic-adults-and-carers
#4
Ye In Jane Hwang, Kitty-Rose Foley, Julian N Trollor
BACKGROUND: "Aging well" is an increasingly popular concept in gerontology. Adults with disabilities such as autism spectrum disorder represent a demographically substantial population, yet remain excluded from existing conceptualizations of aging well. This qualitative study aimed to explore what it means for autistic adults to "age well" from the perspectives of autistic adults and carers. METHODS: Twenty-four semi-structured interviews were conducted with 15 autistic adults (mean age 50...
August 11, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28784193/do-services-meet-the-needs-of-people-with-dementia-and-carers-living-in-the-community-a-scoping-review-of-the-international-literature
#5
Claire Morrisby, Annette Joosten, Marina Ciccarelli
BACKGROUND: Providing effective support to the increasing number of people with dementia to remain at home is a challenge for families, health professionals, service providers, and governments worldwide. The aim of this paper was to summarize and disseminate the current international research evidence on the met and unmet needs of people with dementia and their carers, to inform researchers and policy-makers. METHOD: A scoping review methodology was used to guide a search of studies published between 2004 and 2015 using specified search terms; 27 studies relevant to the aim were included...
August 8, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28784191/person-centered-care-and-engagement-via-technology-of-residents-with-dementia-in-aged-care-facilities
#6
Anita M Y Goh, Samantha M Loi, Alissa Westphal, Nicola T Lautenschlager
Touchscreen technology (TT) is a resource that can improve the quality of life of residents with dementia, and care staff, in residential aged care facilities (RACF) through a person-centered care approach. To enable the use of TTs to engage and benefit people with dementia in RACFs, education is needed to explore how these devices may be used, what facilitates use, and how to address barriers. We sought to provide education and explore RACF staff views and barriers on using TT to engage their residents with dementia...
August 8, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28780910/drug-related-problems-in-community-dwelling-primary-care-patients-screened-positive-for-dementia
#7
D Wucherer, J R Thyrian, T Eichler, J Hertel, I Kilimann, S Richter, B Michalowsky, I Zwingmann, A Dreier-Wolfgramm, C A Ritter, S Teipel, W Hoffmann
BACKGROUND: Older people have a higher risk of drug-related problems (DRPs). However, little is known about the prevalence of DRPs in community-dwelling people who screened positive for dementia. Our study aimed to determine (1) the prevalence and types of DRPs and (2) the socio-demographic and clinical variables associated with DRPs in people screened positive for dementia in primary care. METHODS: The Dementia: life- and person-centered help in Mecklenburg-Western Pomerania (DelpHi-MV) study is a general practitioner (GP)-based cluster-randomized controlled intervention study to implement and evaluate an innovative concept of collaborative dementia care management in the primary care setting in Germany...
August 7, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28766474/a-systematic-review-of-interventions-to-prevent-suicidal-behaviors-and-reduce-suicidal-ideation-in-older-people
#8
Chukwudi Okolie, Michael Dennis, Emily Simon Thomas, Ann John
BACKGROUND: Older people have a high risk of suicide but research in this area has been largely neglected. Unlike for younger age groups, it remains unclear what strategies for prevention exist for older adults. This systematic review assesses the effectiveness of interventions to prevent suicidal behavior and reduce suicidal ideation in this age group. METHODS: MEDLINE, EMBASE, PsycINFO, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched for relevant publications from their dates of inception until 1 April 2016...
August 2, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28766467/sleep-and-mood-in-older-adults-coinciding-changes-in-insomnia-and-depression-symptoms
#9
Michael J Li, Afton Kechter, Richard E Olmstead, Michael R Irwin, David S Black
The aim of this analysis was to test if changes in insomnia symptoms and global sleep quality are associated with coinciding changes in depressed mood among older adults. We report on results yielded from secondary analysis of longitudinal data from a clinical trial of older adults (N = 49) aged 55 to 80 years who reported at least moderate levels of sleep problems. All measures were collected at baseline and after the trial ten weeks later. We computed change scores for two separate measures of disturbed sleep, the Athens Insomnia Scale (AIS) and the Pittsburgh Sleep Quality Index (PSQI), and tested their association with change in depressed mood (Beck Depression Inventory-II; BDI-II) in two separate linear regression models adjusted for biological covariates related to sleep (sex, age, body mass index, and NF-κB as a biological marker previously correlated with insomnia and depression)...
August 2, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28760167/measurement-invariance-across-educational-levels-and-gender-in-12-item-zarit-burden-interview-zbi-on-caregivers-of-people-with-dementia
#10
Chung-Ying Lin, Li-Jung Elizabeth Ku, Amir H Pakpour
BACKGROUND: The Zarit Burden Interview (ZBI) is a commonly used self-report to assess caregiver burden. A 12-item short form of the ZBI has been developed; however, its measurement invariance has not been examined across some different demographics. It is unclear whether different genders and educational levels of a population interpret the ZBI items similarly. Therefore, this study aimed to examine the measurement invariance of the 12-item ZBI across gender and educational levels in a Taiwanese sample...
August 1, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28756788/what-is-good-communication-for-people-living-with-dementia-a-mixed-methods-systematic-review
#11
Sarah Alsawy, Warren Mansell, Phil McEvoy, Sara Tai
BACKGROUND: Many strategies have been recommended to support caregivers in communicating with people who live with dementia. However, less is known about what makes communication a good and meaningful experience from the perspective of people with dementia. Understanding this may enhance the person with dementia's sense of connectedness, strengthen their relationships, and facilitate person-centered care. The current review aimed to evaluate research that examined experiences of communication in people living with dementia...
July 31, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28737120/psychometric-properties-of-the-perceived-stress-scale-in-a-sample-of-german-dementia-patients-and-their-caregivers
#12
Friederike Deeken, Andreas Häusler, Johanna Nordheim, Michael Rapp, Nina Knoll, Nina Rieckmann
BACKGROUND: The aim of the present study was to investigate the psychometric characteristics of the Perceived Stress Scale (PSS) in a sample of dementia patients and their spousal caregivers. METHODS: We investigated the reliability and validity of the 14-item PSS in a sample of 80 couples, each including one spouse who had been diagnosed with mild to moderate dementia (mean age 75.55, SD = 5.85, 38.7% female) and one spousal caregiver (mean age 73.06, SD = 6.75, 61...
July 24, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28737118/subjective-cognitive-decline-is-longitudinally-associated-with-lower-health-related-quality-of-life
#13
Susanne Roehr, Tobias Luck, Alexander Pabst, Horst Bickel, Hans-Helmut König, Dagmar Lühmann, Angela Fuchs, Steffen Wolfsgruber, Birgitt Wiese, Siegfried Weyerer, Edelgard Mösch, Christian Brettschneider, Tina Mallon, Michael Pentzek, Michael Wagner, Silke Mamone, Jochen Werle, Martin Scherer, Wolfgang Maier, Frank Jessen, Steffi G Riedel-Heller
BACKGROUND: Subjective cognitive decline (SCD), the potentially earliest notable manifestation of preclinical Alzheimer's disease and other dementias, was consistently associated with lower quality of life in cross-sectional studies. The aim of this study was to investigate whether such an association persists longitudinally - particularly with health-related quality of life (HRQoL) in older individuals without cognitive impairment. METHODS: Data were derived from follow-up 2-6 of the prospective Germany Study on Ageing, Cognition and Dementia in Primary Care (AgeCoDe) covering a total six-year observation period...
July 24, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28737117/prevalence-and-correlates-of-traumatic-brain-injury-tbi-in-older-adults-results-from-the-well-being-of-the-singapore-elderly-wise-study
#14
Laxman Cetty, Edimansyah Abdin, Janhavi Ajit Vaingankar, Anitha Jeyagurunathan, Boon Yiang Chua, Louisa Picco, Martin Prince, Siow Ann Chong, Mythily Subramaniam
BACKGROUND: Older adults are among the most susceptible to sustain traumatic brain injury (TBI). The study aimed to determine the (1) prevalence of TBI among older adults in Singapore, and (2) socio-demographic, lifestyle, and clinical correlates of TBI. METHODS: Data were extracted from the cross-sectional, Well-being of the Singapore Elderly (WiSE) study. The study included 2,565 participants aged 60 years and above (Mean = 72.75, SD = 9.54). Information on TBI, socio-demographic, and lifestyle factors were collected using participant self-report and verified with the informant report where necessary...
July 24, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28724467/differential-associations-between-sensory-loss-and-neuropsychiatric-symptoms-in-adults-with-and-without-a-neurocognitive-disorder
#15
Kim M Kiely, Moyra E Mortby, Kaarin J Anstey
BACKGROUND: To investigate the differential associations between sensory loss and neuropsychiatric symptoms among older adults with and without diagnosed neurocognitive disorder. METHODS: The sample comprised 1,393 adults (52.3% men) aged between 72 and 79 years from a community-based cohort study. There were 213 cases of mild and 64 cases of major neurocognitive disorders. The main outcome was number of informant reported symptoms on the Neuropsychiatric Inventory (NPI)...
July 20, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28720165/bdnf-val66met-in-preclinical-alzheimer-s-disease-is-associated-with-short-term-changes-in-episodic-memory-and-hippocampal-volume-but-not-serum-mbdnf
#16
Yen Ying Lim, Stephanie Rainey-Smith, Yoon Lim, Simon M Laws, Veer Gupta, Tenielle Porter, Pierrick Bourgeat, David Ames, Christopher Fowler, Olivier Salvado, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Xin Fu Zhou, Ralph N Martins, Paul Maruff
BACKGROUND: The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism Met allele exacerbates amyloid (Aβ) related decline in episodic memory (EM) and hippocampal volume (HV) over 36-54 months in preclinical Alzheimer's disease (AD). However, the extent to which Aβ+ and BDNF Val66Met is related to circulating markers of BDNF (e.g. serum) is unknown. We aimed to determine the effect of Aβ and the BDNF Val66Met polymorphism on levels of serum mBDNF, EM, and HV at baseline and over 18-months...
July 19, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28720164/the-detection-diagnosis-and-impact-of-cognitive-impairment-among-inpatients-aged-65-years-and-over-in-an-irish-general-hospital-a-prospective-observational-study
#17
Clodagh Power, Richard Duffy, Helena Bates, Mike Healy, Petrina Gleeson, Brian A Lawlor, Elaine Greene
BACKGROUND: The diagnosis of dementia remains inadequate, even within clinical settings. Data on rates and degree of impairment among inpatients are vital for service planning and the provision of appropriate patient care as Ireland's population ages. METHODS: Every patient aged 65 years and over admitted over a two-week period was invited to participate. Those who met inclusion criteria were screened for delirium then underwent cognitive screening. Demographic, functional, and outcome data were obtained from medical records, participants, and family...
July 19, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28720158/costs-and-quality-of-life-in-community-dwelling-patients-with-alzheimer-s-disease-in-spain-results-from-the-geras-ii-observational-study
#18
Javier Olazarán, Luis Agüera-Ortiz, Josep María Argimón, Catherine Reed, Antonio Ciudad, Paula Andrade, Tatiana Dilla
BACKGROUND: Country-specific data on resource use and costs associated with Alzheimer's disease (AD) help inform governments about the increasing need for medical and financial support as the disease increases in prevalence. METHODS: GERAS II, a prospective observational study, assessed resource use, costs, and health-related quality of life (HRQoL) among patients with AD and their caregivers in Spain. Community-dwelling patients aged ≥55 years with probable AD, and their primary caregivers, were recruited by study investigators during routine clinical practice and assessed as having mild, moderate, or moderately severe/severe (MS/S) AD dementia based on patient Mini-Mental State Examination scores...
July 19, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28716162/changing-our-thinking-about-changing-their-thinking-in-older-adulthood
#19
Viviana M Wuthrich
It is well-established that as people age, deterioration in cognitive abilities including processing speed, memory, and cognitive flexibility occurs, although vast individual differences occur in the rate and consequences of this decline (Christensen, 2001). Anxiety and depression in late life are also associated with specific cognitive deficits in memory and executive functioning that may impact on new learning (Yochim et al., 2013). Therefore, it is possible that cognitive changes make it more difficult for older adults to learn how to change their thinking particularly in the context of psychological therapy...
July 18, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28714428/are-newly-added-and-lost-confidants-in-later-life-related-to-subsequent-mental-health
#20
Ella Schwartz, Howard Litwin
BACKGROUND: This study examined internal changes in the personal social networks of older people and the relationship between these changes and mental health over time. It focused on two key aspects: emotional closeness and contact frequency with lost and newly added confidants. METHODS: The study was based on data from the fourth (2011) and sixth (2015) waves of the Survey of Health, Ageing and Retirement in Europe (SHARE). The study sample consisted of respondents aged 65 years and older who participated in both waves (n = 14,101)...
July 17, 2017: International Psychogeriatrics
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