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International Journal of STD & AIDS

Florence Huber, Stephanie Vandentorren, Alice Merceron, Amandine Chaponnay, Gueda Gadio, Vincent About, Agathe Pastre, Mathieu Nacher
In French Guiana, 4.5-5.0% of HIV-infected persons experienced an incarceration between 2007 and 2013. A cross-sectional survey was performed to describe the epidemiology and treatment outcomes of a population of HIV-infected inmates in French Guiana. The study population was patients released between 1/2007 and 12/2013, after >30 days of incarceration (n = 147). A secondary objective aimed to identify its main specificities, relative to both the general inmate population and the nonincarcerated HIV population...
January 10, 2019: International Journal of STD & AIDS
Swagata Tambe, Uddhao Zambare, Chitra Nayak
Syphilis and human immunodeficiency virus (HIV) infections are both transmitted sexually. Co-infection of HIV and syphilis alters the course of both diseases. Clinical presentation of syphilis in patients of HIV may be atypical. HIV-infected individuals are at risk of developing lues maligna, which is characterized by nodulo-ulcerative lesions associated with severe constitutional symptoms. Erythroderma secondary to generalized papulo-squamous lesions of secondary syphilis is also uncommon. Here we report two cases of atypical presentations of secondary syphilis in HIV-positive patients...
January 10, 2019: International Journal of STD & AIDS
S Noe, S Heldwein, H Jaeger, M Page, E Wolf
Hyperparathyroidism has been described in people living with HIV undergoing tenofovir disoproxil fumarate (TDF)-containing antiretroviral therapy (ART), but differences in calcium levels have never been investigated in detail. We aimed to compare the prevalence of hypocalcemia between patients with and without TDF-containing ART. The patients and methods were a retrospective cohort study in HIV-infected adult patients receiving dolutegravir and either abacavir (ABC)/lamivudine (3TC) or TDF/emtricitabine in a single center in Munich, Germany...
January 10, 2019: International Journal of STD & AIDS
T H Holtz, W Wimonsate, P A Mock, S Pattanasin, W Chonwattana, W Thienkrua, W Sukwicha, M E Curlin, A Chitwarakorn, E F Dunne
We describe incident human immunodeficiency virus (HIV) and syphilis trends in men who have sex with men (MSM) and transgender women (TGW) presenting for HIV voluntary counseling and testing (VCT) services and sexually transmitted infection (STI) management at the Silom Community Clinic, Bangkok, Thailand. Clients underwent rapid HIV testing and syphilis rapid plasma reagin (RPR) testing. For incidence analysis, we included clients with >1 follow-up visit. Initial negative HIV with subsequent positive HIV defined incident HIV infection; incident syphilis infection was defined as negative RPR followed by positive RPR (titer ≥1:8) and confirmatory anti- Treponema pallidum antibodies...
January 9, 2019: International Journal of STD & AIDS
Rosalind Parkes-Ratanshi, Ruth Kikonyogo, Yu-Hsiang Hsieh, Edith Nakku-Joloba, Yukari C Manabe, Charlotte A Gaydos, Anne Rompalo
Point-of-care tests (POCTs) offer the opportunity for increased diagnostic capacity in resource-limited settings, where there is lack of electricity, technical capacity, reagents, and infrastructure. Understanding how POCTs are currently used and determining what health care workers (HCWs) need is key to development of appropriate tests. In 2016, we undertook an email survey of 7584 HCWs who had received training at the Infectious Diseases Institute, Uganda, in a wide variety of courses. HCWs were contacted up to three times and asked to complete the survey using Qualtrics software...
January 9, 2019: International Journal of STD & AIDS
K J Graves, A P Ghosh, P J Kissinger, C A Muzny
Trichomonas vaginalis (TV) is a parasitic protozoan responsible for the sexually transmitted infection trichomoniasis. Trichomonas vaginalis virus (TVV) is a nonsegmented, 4.5-5 kbp, double-stranded RNA virus, from the Totiviridae family, which inhabits TV. A capsid protein consisting of 120 subunits is covered in channels aiding in RNA release. TVV is closely associated with the Golgi complex and is transmitted vertically. TVV has four subspecies, TVV1, TVV2, TVV3, and TVV4. The clinical significance of TVV and its effect on the pathogenicity of TV is not well known...
January 9, 2019: International Journal of STD & AIDS
Sangeeta Rana, Neil Macdonald, Patrick French, Jay Jarman, Sheel Patel, Mags Portman, Tara Suchak, Ann Sullivan, John White, Paul Crook
Syphilis rates have been increasing in men who have sex with men (MSM) in London. To describe risk behaviour and refine public health interventions, we conducted prospective enhanced surveillance of new syphilis cases in MSM attending selected London sexual health clinics (SHCs) between October 2016 and January 2017. Sexual health advisors (SHAs) completed 107 questionnaires. Eighteen per cent of respondents reported always using condoms, with lower use in HIV-positive (8%, 4/53) than HIV-negative men (33%, 14/52)...
January 8, 2019: International Journal of STD & AIDS
Dovie L Watson, Chuanhong Liao, Jessica Ridgway, John A Schneider
The objective of this study was to describe the sociodemographic characteristics and behavioral factors that are associated with syphilis seroprevalence in a cohort of young Black men who have sex with men (YBMSM) in Chicago, USA (n = 606). The weighted syphilis seroprevalence in the study population was 29.2% (95% CI 23.9, 35.1). A bivariate probit multiple regression model was used to estimate the outcomes. Characteristics that were positively associated with syphilis seropositivity included being age 19-20, 21-24, and at least age 25 compared to the reference group (age 16-18 years old) (0...
January 8, 2019: International Journal of STD & AIDS
Ming J Lee, Serena Venturelli, Wayne McKenna, Jhia Teh, Ojali Negedu, Katia Eh Florman, Esra Musbahi, Angela C Bailey, Nicola E Mackie, Julie Fox, Sarah Fidler
Following changes in national antiretroviral therapy (ART) guidelines removing the CD4 threshold for initiation of ART, we evaluated the time to ART initiation and reasons for delayed or non-initiation. A retrospective notes review of 292 newly diagnosed HIV-positive individuals attending two London clinics between August 2015 and December 2016 was performed. Two hundred and fifty-four of 292 (87%) individuals started ART. Median time to ART initiation was 29 days (range: 0-514). Thirty of 292 (13%) did not start ART...
January 8, 2019: International Journal of STD & AIDS
Vartika Sharma, Waimar Tun, Avina Sarna, Lopamudra R Saraswati, Minh D Pham, Ibou Thior, Stanley Luchters
Unprotected sex, common among people who inject drugs, puts them and their partners at risk of sexually transmitted infections including human immunodeficiency virus (HIV). This analysis assesses the changes in sexual risk behavior with regular female partners (RFPs), among married men who inject drugs, before and after implementation of a HIV prevention intervention, and identifies correlates of unprotected sex. People who inject drugs (PWID) were assessed at three points: baseline, preintervention follow-up visit (FV)1, and postintervention FV2...
December 12, 2018: International Journal of STD & AIDS
Sari L Reisner, Amaya Perez-Brumer, Catherine E Oldenburg, Kristi E Gamarel, Jowanna Malone, Kingsley Leung, Matthew J Mimiaga, Joshua G Rosenberger, Katie B Biello
Cisgender men (CM) who report transgender women (TW) as sexual partners are an understudied population in the HIV epidemic in Latin America. The current study sought to characterize this group in a 2012 cross-sectional online survey of Latin American CM who were members of a sexual networking website for men who have sex with men (N = 11,847). Multivariable logistic regression models were fit to estimate demographic, behavioral, and psychosocial correlates of having a TW sexual partner and engaging in condomless sex...
December 11, 2018: International Journal of STD & AIDS
J Gini, A Amara, Sujan D Penchala, David J Back, L Else, D Egan, J Chiong, Bala I Harri, Elkanah D Kabilis, Paul P Pama, M Stephen, Saye H Khoo
Herbal medication use amongst people living with human immunodeficiency virus (PLWH) is widespread and understudied. This study aimed to evaluate the prevalence of herbal medicine use amongst PLWH and possible contamination with antiretrovirals (ARVs). Countrywide collection of herbal samples sold by street vendors in Nigeria for the following indications: human immunodeficiency virus (HIV), acquired immune deficiency syndrome, fever and general weakness. Samples were screened using a validated liquid chromatography-mass spectrometry/mass spectrometry method for the presence of the following ARVs: efavirenz, nevirapine, lopinavir, darunavir, ritonavir, atazanavir, emtricitabine, tenofovir and lamivudine...
November 30, 2018: International Journal of STD & AIDS
Johanna Denman, Keith Radcliffe
No abstract text is available yet for this article.
November 30, 2018: International Journal of STD & AIDS
Seth C Kalichman, Catherine Mathews, Ellen Banas, Moira O Kalichman
Stigmatization of HIV infection undermines antiretroviral therapy (ART) adherence. The current study examined strategies that people living with HIV employ to manage their ART in stigmatized environments. We conducted an anonymous survey with 439 patients receiving ART at a community clinic in Cape Town, South Africa. Measures included demographic and health characteristics, ART adherence, stigma experiences, efforts to conceal ART to avoid stigma (stigma-medication management strategies), and beliefs that ART nonadherence itself is stigmatizing...
November 30, 2018: International Journal of STD & AIDS
Swagata Tambe, Uddhao Zambare, Chitra Nayak
No abstract text is available yet for this article.
November 28, 2018: International Journal of STD & AIDS
Danielle Ap Rocha, Cássia de Oliveira Moraes, Adriene F Araújo, Êmille Dos Santos Beltrão, Lainara Castelo Dos Santos, Lígia Menezes da Mata, Antônio Nn Xavier, Renato Dos Santos Reis, Sílvia Cc Soares, Kátia L Torres, José E Levi, Josiane M Mariño
Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection among women. In Brazil, there is no organized screening program for C. trachomatis, and the actual prevalence of infection is unknown. This study aimed to determine the prevalence of C. trachomatis infection in women living in riverside communities in the Amazon, using self-collection employing the Evalyn® Brush and polymerase chain reaction. A total of 299 riverine women aged 18-81 years, mean age 35.7 (±12.8) years, predominantly agricultural workers, with low schooling and living with a partner, participated in this study...
November 28, 2018: International Journal of STD & AIDS
Christina A Muzny, Ashutosh R Tamhane, Ellen F Eaton, Kathryn Hudak, Greer A Burkholder, Jane R Schwebke
Trichomonas vaginalis infection contributes to HIV transmission. The study objective was to determine the incidence and predictors of T. vaginalis reinfection among HIV-infected women in Birmingham, Alabama. A retrospective cohort study of women at an urban HIV clinic from August 2014 to March 2016 with T. vaginalis by nucleic acid amplification test (NAAT) was conducted. Time to first episode of reinfection was evaluated using Kaplan-Meier survival curves. The association of various predictors was evaluated by univariate and multivariable Cox proportional hazards analyses...
November 28, 2018: International Journal of STD & AIDS
Gui-Yuan Xiao, Bin Peng, Ying Hu, Dou Qu, Min-Qing Lai, Yu Gong, Feng-Lan Zhao, Hong Yi, Yu Jia, Wei-Kang Zhou, Shan-Chuan Lei, Sha-Li Wang, Jing Xia, Deng-Zhi Lv, Shan Geng, Rong-Li Bai, Xiao-Ni Zhong
With the objective of investigating the characteristics influencing high-risk sexual behaviours in elderly men (60-74 years of age) in Chongqing, China, a total of 1433 healthy elderly men with sexual intercourse frequencies of one to six times/month who were willing to participate in the questionnaires were studied at four hospitals. We measured serum testosterone levels and performed follow-ups every six months, with a total of 1128 elderly men followed up after two years. We also investigated socio-economic and demographic characteristics (age, education, income, location, marital status and number of marriages), types of sexual partners, age differences with fixed sexual partners, frequency of sexual intercourse, combined basic age-related diseases, sexually transmitted infections (STIs) education, elderly self-care ability and high-risk sexual behaviours (frequency of sexual intercourse and number of sexual partners) using questionnaires...
November 28, 2018: International Journal of STD & AIDS
Cynthia A Graham, Lauren B Towler, Richard A Crosby
Errors and problems associated with male condom use are very prevalent and increase the likelihood of inconsistent and incomplete use, thereby compromising condom effectiveness. The aim of this study was to assess the perceived benefits of a new condom wrapper/integrated applicator designed to reduce barriers to condom use and lessen the likelihood of user errors and problems. After viewing videos depicting features of the wrapper/applicator, participants (N = 547; 62.9% male, M age = 29.2) completed online questionnaires...
November 27, 2018: International Journal of STD & AIDS
Hongfang Liu, Beng-Tin Goh, Taoyuan Huang, Yinghui Liu, Ruzeng Xue, Wujian Ke, Mei Gu, Bin Yang
Early syphilis can rarely cause erythema multiforme-type eruptions as well as triggering erythema multiforme (EM). EM-like lesions in secondary syphilis are characterized by clinical features of EM and laboratory tests consistent with secondary syphilis and the skin histology shows predominantly a plasma cell infiltrate with the presence of treponemes. When EM is triggered by early syphilis, the skin histology shows mixed inflammatory cells usually in the absence of treponemes in the skin lesion. There may also be mixed histology with the presence of treponemes in the absence of a plasma cell infiltrate and vice versa...
November 27, 2018: International Journal of STD & AIDS
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