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International Journal of STD & AIDS

Patricia J García, Cesar P Carcamo, Maria Valderrama, Sayda La Rosa, Cerise James, Raul Gutiérrez, Brianna R Lindsay
Genital warts (GW) are mucosal or skin lesions caused by sexual transmission of human papillomavirus (HPV). This study estimates the frequency of GW cases in physicians' clinics and physicians' usual practices of GW referral and diagnosis in Peru. Participants in this study were a convenience sample of 100 physicians in five specialties: primary care (17), gynecology (37), urology (10), dermatology (31), and infectious diseases (5). Physicians completed a survey and daily log of all patients aged 18-60 years seen over ten days in their offices located in Peru...
November 5, 2018: International Journal of STD & AIDS
Sophia Taleghani, Dvora Joseph-Davey, Scott B West, Henry J Klausner, Adriane Wynn, Jeffrey D Klausner
Comprehensive case management of sexually transmitted infections (STIs) includes partner notification. We reviewed the recent literature evaluating the acceptability and efficacy of partner notification strategies (i.e. direct patient referral, provider referral, or expedited partner treatment) for curable STIs in sub-Saharan Africa. We conducted a systematic search following PRISMA guidelines: published January 2008 to June 2017 in the English language, study in sub-Saharan Africa, and discussion of any curable STI with an outcome on partner notification...
November 5, 2018: International Journal of STD & AIDS
Prini Nicholson, Emma Saunsbury, Stefania D'Angelo, Duncan Churchill, Karen Walker-Bone
Gout is the most common inflammatory arthritis worldwide. Its principal risk factor is hyperuricaemia. While gout has been described in HIV patients and numerous more outdated anti-retroviral therapies (ARTs) have been implicated, there have been few recent studies. Our case-control study investigated the prevalence of and risk factors for gout in an established HIV cohort. Cases were identified from database searches using key search terms, with two age- and gender-matched controls. These were compared for demographic factors, co-morbidities, HIV factors and ART exposure...
November 4, 2018: International Journal of STD & AIDS
Emily Mabonga, Rosalind Parkes-Ratanshi, Stefan Riedel, Sheila Nabweyambo, Olive Mbabazi, Chris Taylor, Charlotte Gaydos, Yukari C Manabe
Antimicrobial resistance (AMR) to gonorrhoea is a threat to global health security. There have been concerns expressed that countries with high rates of disease have poor surveillance. The objectives of the study were to determine the AMR patterns of Neisseria gonorrhoeae clinical isolates to antimicrobial agents in patients with HIV or high risk of HIV acquisition, to compare the concordance of disk diffusion and agar dilution as methods for determining AMR to N. gonorrhoeae, and to describe methodological challenges to carrying out AMR testing...
November 4, 2018: International Journal of STD & AIDS
Leire Fernandez-Rollan, Valeria Stuardo A, Susanne Strömdahl
Men who have sex with men (MSM) are disproportionally affected by the HIV epidemic globally. In Chile, HIV prevalence among MSM is estimated at 20%, and condomless anal intercourse is the predominant mode of HIV transmission. This cross-sectional study aimed to estimate a broad array of characteristics in a sample of Chilean MSM including condomless anal intercourse (CLAI), as well as to explore possible associations between these characteristics and CLAI. MSM were recruited through respondent-driven sampling between June and October of 2016...
November 4, 2018: International Journal of STD & AIDS
Mwumvaneza Mutagoma, Laetitia Nyirazinyoye, Dieudonné Sebuhoro, David J Riedel, Joseph Ntaganira
Female sex workers (FSWs) frequently face violence in their working place. This study assessed the physical and sexual violence and associated factors among FSWs in Rwanda. A cross-sectional study was conducted among FSWs in Rwanda in 2015. Venue-Day-Time sampling method was used for recruitment. Descriptive analyses and logistic regression models were computed to assess factors associated with violence. In total, 1978 FSWs were recruited. A large proportion (18.3%) had been sexually abused outside of the family circle, and 37...
November 4, 2018: International Journal of STD & AIDS
Sarah M Michienzi, Christopher A Schriever, Melissa E Badowski
No single-tablet antiretroviral (ARV) regimens (STRs) are approved for patients with human immunodeficiency virus (HIV) and end-stage renal disease (ESRD) on hemodialysis (HD). Based on known pharmacokinetic (PK) properties, abacavir (ABC)/lamivudine (3TC)/dolutegravir (DTG) STR may represent a promising option. This case series presents the safety and efficacy of ABC/3TC/DTG STR in patients with HIV and ESRD on HD. Patients were included if they were HIV-positive, maintained on intermittent HD for ESRD, switched to an ARV regimen containing ABC/3TC/DTG, and had at least one set of virologic data before and after the switch...
October 31, 2018: International Journal of STD & AIDS
Parker Foster, Lori Sokoll, Ji Li, Gary Gerstenblith, Elliot K Fishman, Thomas Kickler, Shaoguang Chen, Hong Tai, Hong Lai, Shenghan Lai
HIV infection and/or antiretroviral therapy may increase the risk of subclinical coronary atherosclerosis. However, patients with chronic kidney disease (CKD) and those without IV access cannot undergo contrast-enhanced coronary CT angiography (CCTA). This study was to explore the relationship between cardiac troponin T (cTnT) levels and the extent of coronary plaque burden, as assessed by CCTA in those with HIV infection. Between June and September 2017, 58 HIV-infected participants were recruited and underwent contrast-enhanced CCTA...
October 31, 2018: International Journal of STD & AIDS
Eileen F Dunne, Sarika Pattanasin, Tareerat Chemnasiri, Anchalee Varangrat, Boonyos Raengsakulrach, Sukwicha Wichuda, Chaiwat Ungsedhapand, Pachara Sirivongrangson, Anupong Chitwarakorn, Timothy H Holtz
We describe participants in the Bangkok Men who have sex with men Cohort Study (BMCS) who sold or bought sex. Men who have sex with men (MSM) and transgender women aged ≥18 years had HIV testing and behavioral data collected at enrollment and every four months. We evaluated report of receiving money or goods for sex (selling sex) or giving money or goods for sex (buying sex) at enrollment using logistic regression models; we also describe sex work over time, and HIV and syphilis incidence among those who report sex work...
October 26, 2018: International Journal of STD & AIDS
Robert Kowalczyk, Krzysztof Nowosielski
Although heterosexual individuals' knowledge of sexually transmitted infections (STIs) has been examined, no studies have been conducted in Poland of the STI knowledge in women who have sex with women (WSW) and women who have sex with women and men (WSWM). We enrolled a group of 146 WSW and 113 WSWM and asked them to complete a study questionnaire that contained items about socioeconomic factors, sexual behaviors, and STI knowledge. The level of STI knowledge among the studied WSW was insufficient. The frequency of correct answers was higher in WSWM...
October 23, 2018: International Journal of STD & AIDS
Andrew Tomkins, Sam Naylor, Emile Morgan
Did not attend (DNA) appointments create a significant impact upon resource and finance efficiency in the NHS. Despite introduction of short-message service (SMS) reminders to our patients, DNA rates remained persistently high. An option to send an SMS to cancel a booked appointment was piloted from 15 January to 16 April 2018 for integrated sexual health and human immunodeficiency virus (HIV) appointments. Absolute monthly mean DNA rates as a proportion of total bookable appointments fell by 2.24% (14.42% pre-intervention [95% CI: 13...
October 23, 2018: International Journal of STD & AIDS
Keenan Withers, Clare Bristow, Minh Nguyen, Chrysovalantis Stafylis, Le M Giang, Jeffrey D Klausner
The SD BIOLINE HIV/Syphilis Duo (SD BIOLINE DUO) rapid test is a dual rapid lateral flow immunoassay that detects antibodies to both human immunodeficiency virus (HIV) and Treponema pallidum (TP) 'syphilis' via fingerprick whole blood. We evaluated the field performance of the SD BIOLINE HIV/Syphilis Duo test among two populations in Hanoi, Vietnam - men who have sex with men (MSM) and pregnant women. We also surveyed factors that influence participants' willingness to test for HIV and syphilis. This test has the potential to increase HIV and syphilis screening in low-resource settings...
October 23, 2018: International Journal of STD & AIDS
Ross D Cranston, Alex Carballo-Diéguez, Holly Gundacker, Barbra A Richardson, Rebecca Giguere, Curtis Dolezal, Aaron Siegel, Ratiya P KunjaraNaAyudhya, Kailazarid Gomez, Jeanna M Piper, Javier R Lama, Ian McGowan
Human papillomavirus (HPV) prevalence varies by population. This study investigated anal HPV type detection risk by country in a population of men who have sex with men (MSM) and transgender women (TW) at risk of HIV. Sexually active HIV-1-uninfected MSM and TW were enrolled at eight sites: four in the United States (US), two in Thailand, one in Peru, and one in South Africa. Baseline anal HPV swabs were collected, and DNA typing was performed. One hundred and ninety-five participants, 76 (42%) from the US, had a mean age of 30...
October 18, 2018: International Journal of STD & AIDS
Heather Farthing, Anamaria Rodriguez, Misha Armstrong, Siddharth Iyengar, Evan Nigh, JoNell Potter, Susanne Doblecki-Lewis
We suggest that people living with HIV (PLWH) may serve as pre-exposure prophylaxis (PrEP) educators for partners when informed about PrEP. Participants in this study were a convenience sample of PLWH at a public hospital in Miami. A cross-sectional survey assessed the frequency of serostatus disclosure, PrEP awareness, and willingness to recommend PrEP to intimate partners. To evaluate stigma surrounding human immunodeficiency virus (HIV), comfort discussing HIV with family, friends and intimate partners was interrogated...
October 9, 2018: International Journal of STD & AIDS
Akarin Hiransuthikul, Supanit Pattanachaiwit, Nipat Teeratakulpisarn, Parinya Chamnan, Panita Pathipvanich, Suchart Thongpaen, Supabhorn Pengnonyang, Deondara Trachunthong, Siriporn Nonenoy, Cheewanan Lertpiriyasuwat, Praphan Phanuphak, Nittaya Phanuphak
We determined subsequent and recurrent sexually transmitted infections (STIs) among men who have sex with men (MSM) and transgender women (TGW) in the Test and Treat cohort. Thai MSM and TGW adults with previously unknown HIV status were enrolled and tested for HIV. Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and syphilis were tested at baseline, month 12, and month 24 to identify subsequent STIs (any STIs diagnosed after baseline) and recurrent STIs (any subsequent STIs diagnosed among those with positive baseline STIs)...
October 9, 2018: International Journal of STD & AIDS
Elizabeth Pearce, Derek J Chan, Don E Smith
Prudent prescribing of antimicrobials is essential in ameliorating the public health problem of antimicrobial resistance. This retrospective audit assesses whether empiric antimicrobial treatment for asymptomatic sexual contacts of sexually transmitted infection is appropriate based on laboratory confirmation.
October 6, 2018: International Journal of STD & AIDS
Azra Khatun, Helen Lotery, Sangeetha Sundaram
Organ transplant recipients are at a higher risk of pre-malignant human papillomavirus-associated lesions due to immunosuppression. The efficacy of immunomodulants such as imiquimod 5% is not yet fully evaluated in this population. We describe a case of vulval intra-epithelial neoplasia in a renal transplant recipient which was successfully treated with topical imiquimod.
October 4, 2018: International Journal of STD & AIDS
Karine Beiruti, Anan Abu Awad, Galina Keigler, Chen Hanna Ryder, Radi Shahien
A previously healthy 35-year-old man suffering from behavioral and mental deterioration for three months was referred to our facility. On admission, the patient was dysphasic and had tonic-clonic seizures. Neurological examination showed mental confusion, euphoric mood, mania, paranoia, and mild motor dysphasia. Magnetic resonance imaging (MRI) was performed twice but no abnormalities were revealed. His acute confusional state, elevated cerebrospinal fluid (CSF) protein, epileptic seizure and electroencephalogram showing intermittent frontal slowness were all suggestive of encephalitis...
September 26, 2018: International Journal of STD & AIDS
Silvia Limonta, Elisa Monge, Michele Montuori, Manuela Morosi, Massimo Galli, Fabio Franzetti
Despite the decline in HIV mortality and morbidity, Pneumocystis jirovecii pneumonia (PJP) is still frequently seen, particularly in patients with a low CD4+ cell count. We present a case series where we analyzed the possible role of lung ultrasound (LUS) in the management of PJP in a real-life clinical setting. We describe the ultrasound findings from a consecutive series of six HIV patients hospitalized for PJP, all with a favorable outcome, and evaluated with LUS at admission in our ward and then repeated this once during the hospitalization...
September 20, 2018: International Journal of STD & AIDS
Mario Puviani, Marco Galluzzo, Marina Talamonti, Sara Mazzilli, Elena Campione, Luca Bianchi, Massimo Milani, Ivano Luppino, Giuseppe Micali
External genital warts (EGW) are the most common viral sexually transmitted infection. Ablative treatments like cryotherapy, curettage, and CO2 laser therapies offer rapid onset of effect, fast clearance, and reduction of virus load. However, these procedures are associated with high recurrence rates (RRs) ranging from 20% to 77% in the short and medium terms and do not provide sustained clearance. After laser therapy removal of EGW, an RR up to 77% has been reported. Topical sinecatechins (TS) 10% is a patient-applied regimen for the treatment of EGW with a low RR (<6...
September 20, 2018: International Journal of STD & AIDS
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