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International Journal of STD & AIDS

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https://www.readbyqxmd.com/read/29113574/a-novel-sexual-health-referral-pathway-for-patients-presenting-to-the-emergency-department-with-gamma-hydroxybutyrate-or-gamma-butyrolactone-overdose
#1
A Hegazi, S Morton, M Pakianathan, C Cosgrove, R Aroney, E Dore, M Hempling
No abstract text is available yet for this article.
December 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28836892/2017-european-guidelines-for-the-management-of-genital-herpes
#2
Rajul Patel, Oliver J Kennedy, Emily Clarke, Anna Geretti, Arvid Nilsen, Stephan Lautenschlager, John Green, Gilbert Donders, Willem van der Meijden, Mikhail Gomberg, Harald Moi, Elizabeth Foley
Genital herpes is one of the commonest sexually transmitted infections worldwide. Using the best available evidence, this guideline recommends strategies for diagnosis, management, and follow-up of the condition as well as for minimising transmission. Early recognition and initiation of therapy is key and may reduce the duration of illness or avoid hospitalisation with complications, including urinary retention, meningism, or severe systemic illness. The guideline covers a range of common clinical scenarios, such as recurrent genital herpes, infection during pregnancy, and co-infection with human immunodeficiency virus...
December 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28492343/multi-level-risk-factors-associated-with-sex-trading-among-women-living-with-hiv-in-kazakhstan-a-neglected-key-population
#3
Alissa Davis, Tina Jiwatram-Negrón, Sholpan Primbetova, Assel Terlikbayeva, Yelena Bilokon, Lyubov Chubukova, Nabila El-Bassel
Little is known about the prevalence and risk factors associated with sex trading among HIV-positive women. A total of 242 HIV-positive women were recruited in five regions in Kazakhstan. These women completed a survey containing items on socio-demographics, HIV stigma, intimate partner violence, and partner risk behaviors. Multivariate regression was used to examine associations between risk factors and sex trading after controlling for socio-demographic factors. Fifty-six (23.1%) women reported trading sex in the past 90 days...
December 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29027897/congenital-syphilis-in-england-and-amendments-to-the-bashh-guideline-for-management-of-affected-infants
#4
Margaret Kingston, Patrick French, Helen Fifer, Gwenda Hughes, Janet Wilson
No abstract text is available yet for this article.
November 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29027896/molluscum-contagiosum-and-pubic-hair-removal-in-male-patients
#5
Gino Antonio Vena, Nicoletta Cassano
No abstract text is available yet for this article.
November 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28345392/informed-consent-for-opt-in-hiv-testing-via-tablet-kiosk-an-assessment-of-patient-comprehension-and-acceptability
#6
Mitra K Lewis, Yu-Hsiang Hsieh, Charlotte A Gaydos, Stephen C Peterson, Richard E Rothman
Although implementation of HIV testing in the emergency department has met with some success, one commonly cited challenge is the consent process. Kiosks offer one potential strategy to overcome this barrier. This pilot cross-sectional survey study examined patient comprehension of opt-in HIV testing consent and acceptability of using a kiosk to provide consent. Subjects were guided through a simulated consent process using a kiosk and then completed a survey of consent comprehension and acceptability of kiosk use...
November 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28901844/acute-hepatitis-c-in-hiv-uninfected-men-who-have-sex-with-men-who-do-not-report-injecting-drug-use
#7
Colin Fitzpatrick, Nicolas Pinto-Sander, Deborah Williams, Daniel Richardson
No abstract text is available yet for this article.
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28632477/antiretroviral-therapy-adherence-and-self-efficacy-among-people-living-with-hiv-and-a-history-of-drug-use-in-vietnam
#8
Li Li, Chunqing Lin, Sung-Jae Lee, Le Anh Tuan, Nan Feng, Nguyen Anh Tuan
People living with HIV with a history of drug use face additional psychosocial challenges that could compromise their adherence to antiretroviral therapy (ART). This study examined ART treatment adherence and adherence self-efficacy among people living with HIV with a history of drug use in Vietnam. We used cross-sectional baseline data collected between October 2014 and February 2015 from a randomized controlled trial in Vietnam. Of the 900 persons with a history of drug use in the trial, a sample of 109 people living with HIV currently on ART were included in the study...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28632476/extensive-brain-masses-and-cavitary-lung-lesions-associated-with-toxoplasmosis-and-acquired-immunodeficiency-syndrome
#9
Folusakin Ayoade, John Todd, Firas Al-Delfi, John King
Toxoplasmosis is an important cause of enhancing brain lesions in patients with acquired immunodeficiency syndrome (AIDS), and it is typically associated with low CD4-lymphocyte counts. Extensive toxoplasma encephalitis when the CD4-lymphocyte count is above 100 cells/µl is unusual. Cavitary lung lesions are also not typically associated with toxoplasmosis. Here, we present a case of toxoplasmosis associated with extensive brain masses and cavitary lung lesions, both of which improved with directed toxoplasmosis therapy, in an AIDS patient with a CD4 cell count of 120 cells/µl...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28632475/generic-substitution-of-antiretrovirals-patients-and-health-care-providers-opinions
#10
Jennifer A Kieran, Eimear O'Reilly, Siobhan O'Dea, Colm Bergin, Aisling O'Leary
There is interest in introducing generic antiretroviral drugs (ARVs) into high-income countries in order to maximise efficiency in health care budgets. Studies examining patients' and providers' knowledge and attitudes to generic substitution in HIV are few. This was a cross-sectional, observational study with a convenience sample of adult HIV-infected patients and health care providers (HCPs). Data on demographics, knowledge of generic medicine and facilitators of generic substitution were collected. Descriptive and univariate analysis was performed using SPSS V...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28632474/evaluation-of-the-concurrent-use-of-dolutegravir-and-metformin-in-human-immunodeficiency-virus-infected-patients
#11
Anne Masich, Melissa E Badowski, Michelle D Liedtke, Patricia P Fulco
An analysis of the interaction between dolutegravir and metformin was conducted in the HIV ambulatory clinic setting. This was a multicenter, retrospective case series evaluating adult, HIV-infected patients concurrently prescribed dolutegravir and metformin. Historical electronic medical records were utilized to collect case-specific data. Laboratory parameters including serum creatinine (SCr), hemoglobin A1c (HgbA1c), plasma HIV RNA, CD4 cell count, and lactate were reviewed. Adverse drug reactions were assessed using patient-reported gastrointestinal intolerance and hypoglycemic symptoms...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28403692/severe-hypokalemia-due-to-a-possible-drug-drug-interaction-between-vinblastine-and-antiretrovirals-in-a-hiv-infected-patient-with-hodgkin-s-lymphoma
#12
Ezequiel Cordova, Laura Morganti, Andrea Odzak, Florencia Arcondo, Mariana Silva, Marcelo Zylberman, Claudia Rodriguez
A 60-year-old HIV-1 infected woman on antiretroviral therapy (emtricitabine/tenofovir, and ritonavir-boosted atazanavir) developed Hodgkin's lymphoma. The patient initiated ABVD (doxorubicin, bleomycin, vinblastine and dacarbazine) chemotherapy and presented with neutropenia and severe hypokalemia. Hypokalemia was considered as part of a proximal tubular renal dysfunction, and other causes of hypokalemia were excluded. Due to suspicion of drug--drug interactions between antiretrovirals and vinblastine, ritonavir-boosted atazanavir was switched to dolutegravir and the patient continued emtricitabine/tenofovir...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28152664/self-rated-health-and-substance-use-among-individuals-in-hiv-care-in-rio-de-janeiro-brazil-a-cross-sectional-study
#13
Iona K Machado, Paula M Luz, Jordan E Lake, Rodolfo Castro, Luciane Velasque, Jesse L Clark, Valdilea G Veloso, Beatriz Grinsztejn, Raquel B De Boni
Self-rated health (SRH) is associated with morbidity and mortality in HIV-uninfected populations but is understudied in HIV. Substance use may affect SRH in addition to its deleterious effect on HIV disease. This analysis aimed to estimate SRH and substance use prevalence and evaluate factors associated with poor SRH among individuals in HIV care in Rio de Janeiro, Brazil. A convenience sample of HIV-infected adults completed one item of SRH, the Alcohol, Smoking and Substance Involvement Screening Test, and the Patient Health Questionnaire-2 (PHQ-2)...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28134005/chlamydia-trachomatis-neisseria-gonorrhoeae-and-trichomonas-vaginalis-screening-and-treatment-of-pregnant-women-in-port-au-prince-haiti
#14
Claire C Bristow, Patricia Mathelier, Oksana Ocheretina, Daphne Benoit, Jean W Pape, Adriane Wynn, Jeffrey D Klausner
In Haiti, routine screening for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) among pregnant women is not conducted; yet these sexually transmitted infections (STIs) are associated with adverse birth and newborn health outcomes. We aimed to assess the acceptability and feasibility of screening and the prevalence of STIs among pregnant women in Port-au-Prince, Haiti. Pregnant women of at least 18 years of age who attend Haitian Study Group for Kaposi's sarcoma and Opportunistic Infections (GHESKIO) clinics in Port-au-Prince, Haiti provided self-collected vaginal swab specimens...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28120646/prevalence-and-the-associated-risk-factors-of-hiv-stis-and-hbv-among-men-who-have-sex-with-men-in-kunming-china
#15
Xiujie Zhang, Manhong Jia, Min Chen, Hongbing Luo, Huichao Chen, Wei Luo, Wanyue Zhang, Yanling Ma, Chaojun Yang, Yanling Yang, Xiaobin Zhang, Jie Dai, Lijuan Dong, William Cw Wong, Pengfei Zhao, Lin Lu
To investigate the prevalence and the associated risk factors of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and sexually transmitted infections (STIs) among men who have sex with men (MSM) in Kunming, 300 MSM were recruited through community-based organizations between September 2014 and January 2015. The prevalence of HIV, HBsAg, syphilis, Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) were 17.0%, 7.7%, 11.3%, 18.2% and 13.2%, respectively. In the three different anatomic sites (urethra, rectum and pharynx), the prevalence of rectal CT was the highest (15...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28120644/risk-behaviours-and-prevalences-of-hiv-and-sexually-transmitted-infections-among-female-sex-workers-in-various-venues-in-changzhou-china
#16
Yanli Guo, Xiaoguo Xu, Gengfeng Fu, Xiping Huan, Ning Jiang, Yueping Yin, Xiangsheng Chen
Female sex workers (FSWs) play an important role in the heterosexual transmission of HIV and sexually transmitted infections (STIs) in China. We conducted a cross-sectional study of 609 FSWs from various venues in Changzhou to investigate risk behaviours and prevalences of HIV and STIs among FSW subgroups. Structured questionnaires were used in face-to-face interviews to collect information. Blood and cervical specimens were collected to test for HIV, syphilis, Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) infections...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28118803/meta-analysis-of-the-efficacy-of-moxifloxacin-in-treating-mycoplasma-genitalium-infection
#17
Yang Li, Wen-Jing Le, Sai Li, Yu-Ping Cao, Xiao-Hong Su
Mycoplasma genitalium is an important pathogen that is transmitted through sexual contact. For patients diagnosed with M. genitalium infection, the current guidelines recommend 1 g of azithromycin as the first-line treatment. Moxifloxacin is used as a second-line drug due to its remarkable efficacy; however, increased use of moxifloxacin to treat M. genitalium infections has caused the emergence of cases of moxifloxacin treatment failure. This meta-analysis aims to estimate the treatment efficacy of moxifloxacin for M...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28118802/does-community-based-point-of-care-hiv-testing-reduce-late-hiv-diagnosis-a-retrospective-study-in-england-and-wales
#18
Nell Freeman-Romilly, Paula Sheppard, Sarika Desai, Nick Cooper, Michael Brady
The objective of this study was to investigate if patients diagnosed in community clinics have higher baseline CD4 cell counts than those diagnosed in Genitourinary medicine (GUM)/HIV clinics. We undertook a retrospective review of baseline CD4 cell counts for patients receiving a reactive HIV test in community-testing clinics. Eleven local HIV clinics were contacted to determine the baseline CD4 cell counts of these patients. Baseline CD4 cell counts of those diagnosed in the community were compared with mean local GUM/HIV clinic and median national baseline CD4 cell count for their year of diagnosis...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28118801/early-clinical-experience-of-dolutegravir-in-an-hiv-cohort-in-a-larger-teaching-hospital
#19
Sej Todd, P Rafferty, E Walker, M Hunter, W W Dinsmore, C M Donnelly, E J McCarty, S P Quah, C R Emerson
Dolutegravir (DTG) is the third HIV integrase inhibitor (INI) available for prescription in Belfast since July 2014. It has shown high virological efficacy in both treatment-naïve and -experienced patients. We carried out a retrospective case chart analysis of HIV-1-positive adults commenced on DTG between July 2014 and September 2015. Patients were identified from records as either treatment-naïve or antiretroviral therapy (ART) experienced. Outcomes included: (1) virological response (HIV-1 RNA viral load at 0, 4, 8 and 12 weeks), (2) immunological response (CD4+ cell count at 0, 4, 8 and 12 weeks) and (3) tolerability (side effects and discontinuation)...
October 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28114880/factors-associated-with-patients-who-prefer-hiv-self-testing-over-health-professional-testing-in-an-emergency-department-based-rapid-hiv-screening-program
#20
Yu-Hsiang Hsieh, Kaylin J Beck, Richard E Rothman, Megan Gauvey-Kern, Alonzo Woodfield, Stephen Peterson, Danielle Signer, Charlotte A Gaydos
Kiosk-facilitated HIV self-testing has been shown to be accurate and well accepted by emergency department (ED) patients. We investigated factors associated with patients who preferred self-testing over testing performed by health professionals in an ED-based HIV screening program. This opt-in program evaluation studied 332 patients in an inner-city academic ED from February 2012 to April 2012, when a kiosk-based HIV self-testing program was standard of care. The first kiosk in the 2-stage system registered patients and assessed their interest in screening, while the second kiosk gathered demographic and risk factor information and also provided self-testing instructions...
October 2017: International Journal of STD & AIDS
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