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Revista Española de Enfermedades Digestivas

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https://www.readbyqxmd.com/read/30449124/expanding-the-mutational-spectrum-of-the-abcb4-gene-in-inherited-adult-cholestatic-liver-disorders-with-four-novel-pathogenic-variants-case-reports
#1
Minh Tuan Huynh, Jean-Louis Delaunay, Laure Muller, Christophe Corpechot, Cong Toai Tran, Véronique Barbu
Low phospholipid-associated cholelithiasis and intrahepatic cholestasis of pregnancy are two MDR3-related inherited liver disorders caused by biallelic or monoallelic ABCB4 loss-of-function variants. Low phospholipid-associated cholelithiasis is clinically characterized by the early onset of symptomatic cholelithiasis in young adults while intrahepatic cholestasis of pregnancy is a distinct clinical entity associated with adverse fetal outcomes. Of note, patients carrying ABCB4 sequence variations commonly exhibit phenotypic expression over a wide continuum due to environmental and hormonal contributing factors and genetic modifiers...
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449123/pelvic-hydatidosis-an-exceptional-location
#2
Alba Manuel Vázquez, Raquel Latorre Fragua, Luis Gijón de la Santa, José Manuel Ramia
Hydatid disease is a zoonosis, still endemic in some Spanish geographical areas. Extrahepatic-extrapulmonary lesions account for only 10%, with pelvic lesions being exceptional. We present two patients with pelvic hydatidosis, with or without concomitant liver injury. Treatment depends on the cyst, location and symptoms. Surgery is mandatory if there is any complication.
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449122/healing-of-autoimmune-hepatitis-associated-with-hepatitis-c-virus-infection-treated-with-direct-acting-antivirals
#3
Laura López Couceiro, Elena Gómez Domínguez, Raquel Muñoz Gómez, Gregorio Castellano Tortajada, Carolina Ibarrola de Andrés, Inmaculada Fernández Vázquez
The use of direct-acting antivirals (DAA) for the hepatitis C virus (HCV) has yielded a significant improvement in the treatment of autoimmune hepatitis (AIH) associated with HCV infection. Interferon was the cornerstone of HCV therapy before the introduction of these agents into the clinical practice. Herein, we report the case of an HCV-infected patient who developed an interferon-induced AIH and since then, has received immunosuppressive therapy. Administration of DAA resulted in a sustained virologic response (SVR) and clinical AIH remission which allowed a discontinuation of immunosuppressive treatment...
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449121/subtotal-cholecystectomy-versus-cholecystostomy
#4
Sayantan Bhattacharya
Emergency laparoscopic cholecystectomy (LC) is associated with a higher morbidity and mortality, as compared to elective LC. A two-fold increase in 30-day re-admission after LC was associated with two or more pre-operative admissions with symptoms of cholecystitis, as opposed to index-admission-LC (IALC). This was presumably because of more inflammation due to repeated attacks of cholecystitis in the former cohort, making gallbladders more "difficult". Inflamed gallbladders with higher Nassar-scores (scores 3 and 4) also have significantly raised complication rates...
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449120/colon-perforation-due-to-fistulization-of-a-pancreatic-pseudocyst
#5
María Del Mar Díaz Alcázar, Joaquín García Márquez, Adelina García Robles, Beatriz Zuñiga de Mora Figueroa
We present a computed tomography image of a patient with acute necrotizing pancreatitis due to alcohol, who developed several pseudocysts, one of which fistulized into the colon.
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449119/evaluation-of-the-medical-economics-and-safety-two-methods-for-the-endoscopic-removal-of-jujube-pits
#6
Chunmei Guo, Jing Wu, Haiyan He, Hong Liu, Yadan Wang, Nan Wei, Canghai Wang, Wu Lin, Hui Su
OBJECTIVE: to evaluate the medical economics and safety of two methods for the endoscopic removal of jujube pits, one with a transparent cap combined with a stone basket and the other with a transparent cap combined with foreign body forceps. METHODS: consecutive patients with a suspected jujube pit ingestion in the esophagus between January 2008 and December 2017 were enrolled into the study. Fifty-three patients who met the criteria were divided into two groups...
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449118/prognostic-differences-between-lymphoepithelioma-like-colon-carcinoma-and-colon-adenocarcinoma
#7
Inmaculada Lendínez Romero, Cristina González Puga, Pedro García Saura
Lymphoepithelioma-like colon carcinoma (LELC) is rare. The Epstein-Barr virus (EBV) hasn´t been implicated in the pathogenesis of LELC of the colon, but they may in fact be more strongly associated with MSI. Its treatment is identical to adenocarcinoma. However, lymphocyte infiltration and microsatellite instability have been associated with better prognosis.
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449117/supraumbilical-skin-necrosis-after-repeat-transarterial-chemoembolization
#8
Jasone Larrea Oleaga, Mikel Prieto Calvo, Mikel Gastaca Mateo
Transcatheter arterial chemoembolization TACE is an effective treatment for stage BCLC-B hepatocellular carcinoma (1). The development of skin lesions in the supraumbilical region is an unusual complication following this procedure. We report the case of an 80-year-old male with alcoholic liver cirrhosis, portal hypertension PHT (Child-Pugh A) and multifocal hepatocellular carcinoma. The patient had already undergone four radiofrequency ablations, one alcoholization procedure and four TACEs via femoral access...
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449116/influence-of-infant-feeding-on-the-excretion-of-gluten-immunopeptides-in-feces
#9
Libia Quero Acosta, Cristoba Coronel Rodríguez, Federico Argüelles Martín
INTRODUCTION: the secretion of antigens from the diet into breast milk has been extensively documented. The transfer of gliadin could be critical for the development of an immune response. OBJECTIVES: to investigate the presence of immunogenic gluten peptides in the feces of infants fed with different diets. MATERIAL AND METHODS: a blind, prospective, controlled, collaborative study was performed in three hospitals, between September 2016 and January 2017...
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449115/treatment-of-gastric-gist-using-endoscopic-techniques-combined-with-the-application-of-endoloop-and-intralesional-cyanoacrylate-in-a-non-surgical-patient
#10
Gabriel Mosquera-Klinger, Carlos de la Serna Higuera, Manuel Pérez-Miranda
We present the case of a 79-year-old patient with multiple cardiovascular morbidities, classified as ASA III (American Society of Anesthesiology). An upper digestive endoscopy was performed due to chronic anemia and a subepithelial lesion was identified in the subcardial region of 30 x 25 mm, without other relevant findings.
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449114/a-foreign-body-in-the-small-bowel-a-rare-entity-of-acute-abdomen
#11
Antonio Garrido Serrano, Paula Fernández Álvarez
Acute abdomen secondary to intestinal impactation due to ingestion of foreign body is a rare entity. We report a 73-year-old male patient who presented ileal perforation due to ingestion of a fishbone.
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30449113/black-stomach-acute-gastric-wall-ischemia-due-to-polycythemia-of-an-unknown-origin
#12
Richard Azevedo, Flávio Pereira, Ana Caldeira
Acute ischemia of the gastric mucosa, resulting in a black stomach, is a very rare event given the blood supply of the stomach, with a rich collateral blood flow system. We present the case of a 65-year-old man, with polycythemia of unknown origin under investigation, presented to the emergency department with a history of diffuse abdominal pain and hematemesis. Blood tests revealed a hemoglobin level of 22 g/dL.Upper endoscopy revealed a black ulcerated gastric mucosa compatible with acute necrosis of the corpus and antrum of the stomach ...
November 19, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30421959/endoscopic-sump-syndrome-secondary-to-eus-guided-choledocho-duodenostomy-with-a-lumen-apposing-metal-stent
#13
Gabriel Mosquera-Klinger, Carlos de la Serna Higuera, Manuel Pérez-Miranda
Sump syndrome (SS) is associated with choledocho-duodenostomy (CDD) dysfunction, which occurs due to accumulation of detritus, biliary mud and food remains in the suprapapillary distal common bile duct. The prevalence is low after CDD. Currently, biliary drainage endoscopic ultrasound (EUS)-guided with a lumen-apposing metal stent (LAMS) is a new minimally invasive alternative for biliary stenosis for patients in whom endoscopy retrograde cholangial-pancreatography (ERCP) is not feasible. CDD via EUS-guided LAMS is increasing...
November 13, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30421958/perforated-emphysematous-cholecystitis-and-streptococcus-bovis
#14
Ismael Mora-Guzmán, Elena Martín-Pérez
Streptococcus bovis is an uncommon cause of biliary tract infection, being acute cholecystitis including this microorganism extremely rare. This entity is more frequent in older patients with cardiovascular disease, diabetes, hepatitis, or neoplasms as colon cancer.
November 13, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30421957/klatskin-tumors-and-klatskin-mimicking-lesions-our-22-year-experience
#15
Konstantinos Tsalis, Styliani Parpoudi, Dimitrios Kyziridis, Orestis Ioannidis, Natalia Antigoni Savvala, Nikolaos Antoniou, Savvas Symeonidis, Dimitrios Konstantaras, Ioannis Mantzoros, Manousos-Georgios Pramateftakis, Efstathios Kotidis, Stamatios Angelopoulos
Background and study purpose: Hilar cholangiocarcinoma, also known as Altemeier-Klatskin tumor, is a rare malignancy that arises in the confluence of the hepatic ducts of the porta hepatis. The prognosis is rather poor. Several lesions mimic these tumors and lead to a misdiagnosis, resulting in radical hepatic resections. These lesions are known as Klatskin-mimicking lesions. We present our experience with the diagnosis and treatment of pathological lesions that can mimic a perihilar cholangiocarcinoma and establish an algorithm of treatment Methods: For the current retrospective study, a prospectively established bile-duct tumor database was analyzed by selecting patients with a preoperative diagnosis of perihilar cholangiocarcinoma...
November 13, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30421956/consensus-document-on-exclusion-diets-in-irritable-bowel-syndrome-ibs
#16
Francesc Casellas, Rosa Burgos, Ascensión Marcos, Javier Santos, Constanza Ciriza de Los Ríos, Álvaro García Manzanares, Isabel Polanco, María Puy Portillo, Antonio Villarino, Beatriz Lema Marqués, María Del Carmen Vázquez Alférez
This paper summarizes the contents of a consensus document on exclusion diets in irritable bowel disease that was developed by a task force from SEPD, FEAD, SENPE, FESNAD, SEÑ, SEEN, SEGHNP, SEDCA and ADENYD. The complete document is available at the FEAD and in SENPE websites. Irritable bowel syndrome is a highly prevalent functional digestive disorder where, in addition to drugs, therapy includes diet and acquisition of healthy habits as basic elements for its control. In order to facilitate dietary counseling for these patients in daily practice, the present consensus document on the role of exclusion diets was developed...
November 13, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30421955/hepatitis-b-virus-in-patients-with-chronic-hepatitis-c-treated-with-direct-antiviral-agents
#17
María Luisa Gutiérrez García, María Luisa Manzano Alonso, Juan Ángel Ferrer Rosique, Raquel Muñoz Gómez, Sonia Alonso López, Inmaculada Fernández Álvarez, Conrado M Fernández Rodríguez
INTRODUCTION: cases of hepatitis B virus (HBV) reactivation have been reported in patients with hepatitis C virus (HCV) treated with direct antiviral agents (DAA). OBJECTIVES AND METHODS: the main objectives of the present study are: a) to determine the prevalence of HBV/HCV coinfection in HCV patients treated with DAAs in the Autonomous Community of Madrid (CM) and also to determine the incidence and clinical relevance of HBV reactivation; and b) to determine the HBV screening rates in HCV patients in our region...
November 13, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30424678/a-descriptive-monitoring-study-of-a-non-anesthetist-sedation-quality-program
#18
Rafael Cabadas Avión, María Sonsoles Leal Ruiloba, Santiago Vázquez López, María Ojea Cendón, Ismail Wi Hijazi, María Aurora Baluja González, Julián Álvarez-Escudero
INTRODUCTION: sedation substantially improves the quality of digestive endoscopy procedures but may result in severe complications. METHODS: a joint commission-based multidisciplinary protocol was used to define a protocol for sedation by non-anesthesiologists. ASA 4 patients were excluded, as well as patients with a difficult airway, complex procedures and deep sedation. Quality based on the analysis of 9 indicators were monitored. Incomplete procedures were also monitored in order to assess efficacy...
November 12, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30404529/cystic-tumors-of-the-pancreas-an-update-of-the-surgical-experience-in-a-single-institution
#19
Luis Hurtado Pardo, Javier A Cienfuegos, Javier Antoñanzas, Alberto Benito, Pablo Panadero, Joseba Salguero, Pablo Martí-Cruchaga, Gabriel Zozaya, Víctor Valentí, Fernando Pardo, Fernando Rotellar, José Luis Hernández Lizoáin
BACKGROUND: the aim of the present study was to analyze the clinicopathological features of patients undergoing pancreatic surgical resections due to cystic neoplasms of the pancreas. MATERIAL AND METHODS: demographic data, form of presentation, radiologic images and location of the tumors within the pancreas were analyzed. Data was also collected on the type of surgery (open/laparoscopic), postoperative complications and their severity and oncologic outcomes. RESULTS: eighty-two pancreatic resections were performed...
November 8, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30404528/clinicopathologic-factors-associated-with-recurrence-and-long-term-survival-in-node-negative-advanced-gastric-cancer-patients
#20
Bochao Zhao, Xinyu Huang, Jiale Zhang, Rui Luo, Huiwen Lu, Huimian Xu, Baojun Huang
BACKGROUND: despite a better prognosis in node-negative advanced gastric cancer (GC), a proportion of patients have a tumor recurrence within five years and eventually die due to cancer-related causes. The present study aimed to evaluate the predictive factors of tumor recurrence and long-term survival in node-negative advanced GC. METHODS: a total of 646 node-negative advanced GC patients who underwent a curative gastrectomy in our institution were included in the study...
November 8, 2018: Revista Española de Enfermedades Digestivas
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