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Revista Española de Enfermedades Digestivas

Eduardo Espinet Coll, Gontrand López-Nava Breviere, Javier Nebreda Durán, Carlos Marra-López Valenciano, Román Turró Arau, José Miguel Esteban López-Jamar, Miguel Muñoz-Navas
Obesity is a chronic multifactorial, incurable, recurrent, and progressive disease associated with significant physical and psychological complications, and considerable morbidity and mortality. For this reason, the assessment, management, and follow-up of obese patients should take place in the setting of a multidisciplinary unit equipped with adequate human and structural resources. Medical treatment using hygienic-dietary measures, while indispensable, may be insufficient, and surgery, which is reserved for severe or morbid obesity, is not exempt from complications neither is to the liking of many patients...
May 16, 2018: Revista Española de Enfermedades Digestivas
Jesús Espinel Díez, María Eugenia Pinedo, Belén Bernad
Nowadays, some endoscopists believe that knowing a patient has common bile duct stones (CBDS) is not enough. An added value is required that allows the endoscopist performing the endoscopic retrograde cholangiopancreatography (ERCP) to obtain accurate and useful information in order to offer the best management of the condition. The added value of magnetic resonance cholangiopancreatography (MRCP) is attractive and can contribute to the success of the procedure.
May 9, 2018: Revista Española de Enfermedades Digestivas
Eduardo Espinet Coll, Javier Nebreda Durán, Gontrand López-Nava Breviere, Manoel Galvao Neto, José Antonio Gómez Valero, Silvia Bacchiddu, Carmen Vila Lolo, Patricia Díaz Galán, Inmaculada Bautista-Castaño, Antonio Juan-Creix Comamala
INTRODUCTION: many patients that undergo bariatric surgery (Roux-en-Y gastric bypass [RYGB]) may regain some of their weight lost over time. A transoral outlet reduction (TORe) with endoscopic suture could be a valid alternative in these patients. METHODS: this was a retrospective initial series of 13 consecutive patients with weight regain after RYGB and a dilated gastro-jejunal anastomosis (> 15 mm). TORe was performed using an endoscopic transmural suture device (OverStitch-Apollo®), which was used to reduce the anastomosis aperture and also to treat the gastric pouch...
May 9, 2018: Revista Española de Enfermedades Digestivas
Eva Barreiro Alonso, Javier Santamaría Del Tío, Eva María Fonseca Aizpuru
Listeria monocytogenes can cause invasive disease in immunocompromised patients. We have retrospectively reviewed the clinical characteristics, treatment and evolution of the cases of listeriosis registered at our center during a long period of 14 years. Listeria monocytogenes infection is potentially serious with high mortality. Therefore, a high index of suspicion and early directed antibiotic treatment are needed, especially for immunocompromised patients.
May 9, 2018: Revista Española de Enfermedades Digestivas
Weijia Duan, Xiaojuan Ou, Xiaoming Wang, Yu Wang, Xinyan Zhao, Qianyi Wang, Xiaoning Wu, Wei Zhang, Hong Ma, Hong You, Jidong Jia
BACKGROUND: primary biliary cholangitis (PBC) patients with a suboptimal response to ursodeoxycholic acid (UDCA) have a significantly worse survival rate. Fenofibrate has been shown to improve the short-term biochemical response in this group of patients. However, there is limited data available on the safety and efficacy of its long-term use, especially in patients with cirrhosis. Methods:in this retrospective cohort study, fenofibrate was given to PBC patients with a suboptimal response to at least 12 months of UDCA (13-15 mg/kg/d) therapy...
May 9, 2018: Revista Española de Enfermedades Digestivas
Julio Iglesias García, José Lariño-Noia, Ihab Abdulkader Nallib, Björn Lindkvist, J Enrique Domínguez-Muñoz
BACKGROUND: diagnosis of early chronic pancreatitis (CP) is hampered due to the low accuracy of current imaging techniques and the absence of methods for histological confirmation. We aimed to evaluate the efficacy of endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for the histological diagnosis of early CP. METHODS: a prospective, cross-sectional, single-center study was designed. Consecutive patients referred for EUS with a clinical suspicion of CP were evaluated for inclusion into the study...
May 3, 2018: Revista Española de Enfermedades Digestivas
Alicia Martín-Lagos Maldonado, Myriam Del Carmen Herrera Mercader, Cristina Lozano Cejudo
Lymphogranuloma venereum (LGV) is a condition caused by invasive serovars of Chlamydia trachomatis. The classical inguinal presentation that is characterized by the development of transient genital ulcer(s) and inguinal or femoral lymphadenopathy has decreased in our environment. At present, infection by this bacterium has emerged as an important cause of proctitis and proctocolitis in men who have sex with other men. We report the case of a homosexual man with acute proctitis that was complicated by a perirectal abscess secondary to a Chlamydia trachomatis infection...
May 3, 2018: Revista Española de Enfermedades Digestivas
Susana Castaninha, Joao Carlos Lopes, Ana Isabel Lopes
Eosinophilic esophagitis (EoE) is a chronic immune-mediated esophageal disease, with a rising incidence in childhood. The diagnosis is confirmed by esophageal mucosa eosinophil-predominant inflammation. Rare complications, such as intramural esophageal dissection (IED) due to progressive transmural inflammatory and fibrotic process, may occur in young adults. While severe cases can require immediate surgical intervention, conservative management may be also effective, as recently reported by Ibáñez-Sanz et al...
May 3, 2018: Revista Española de Enfermedades Digestivas
Begoña Márquez Argente Del Castillo, José Ramón Olalla Muñoz
Pneumatosis intestinalis refers to lineal or cystic gas collections in the intestinal wall. Pneumatosis cystoides intestinalis (PCI) is a benign primary cause. This is a rare disease characterized by multiple gas cysts in the submucosa or subserosa, principally within the colon.
May 3, 2018: Revista Española de Enfermedades Digestivas
Concepción Núñez, José Antonio Garrote, Eduardo Arranz, José Ramón Bilbao, Fernando Fernández Bañares, Juana Jiménez, Teresa Perucho, Eva Ruiz Casares, Félix Sánchez-Valverde, Nacho Serrano
Coeliac disease (CD) is a chronic autoimmune enteropathy triggered by gluten and related prolamines in genetically predisposed individuals. Although CD is a polygenic disease, there is a strong association with genes of the human leukocyte antigen (HLA) region. Most patients present the HLA-DQ2 heterodimer, specifically the DQ2.5 isoform, which is present in around 90-96% of patients of European ancestry.
May 3, 2018: Revista Española de Enfermedades Digestivas
Eva Martínez-Ojinaga, Manuel Molina, Isabel Polanco, Elena Urcelay, Concepción Núñez
AIMS: celiac disease is a multisystem immune-mediated disease triggered by gluten in genetically susceptible individuals. The HLA-DQ2 and/or HLA-DQ8 heterodimers are encoded by the main genetic predisposing factors and their presence is required for the development of the immunological response that leads to the disease. However, the HLA-conferred risk can differ within different countries. The aim of the study was to analyze the risk of Spanish children to develop celiac disease according to their HLA-DQ genotype...
April 27, 2018: Revista Española de Enfermedades Digestivas
Paula Crespo Escobar, Gemma Castillejo, Eva Martínez-Ojinaga, Ester Donat, Isabel Polanco, María Luisa Mearin, Carmen Ribes-Koninckx
AIM: to evaluate the influence of gluten consumption on celiac disease development and to describe its natural history in the Spanish cohort of the European PreventCD study. METHODS: prospective multi-center double blind study of 225 children that were followed up from birth. All cases were HLA-DQ2/HLA-DQ8 positive with a 1st degree relative with celiac disease and were followed up in three centers from Madrid, Reus and Valencia. Gluten intake was determined between four and ten months according to the protocol...
April 27, 2018: Revista Española de Enfermedades Digestivas
Sónia Bernardo, Ana Rita Gonçalves, Luís Araújo-Correia
The coexistence of systemic sclerosis (SSc) and sarcoidosis is an extremely rare phenomenon; some studies question its existence. We report the case of a male with a diagnosis of sarcoidosis that was admitted due to abdominal distension and pain. After a thorough investigation, he was diagnosed with severe chronic intestinal pseudo-obstruction as a manifestation of SSc.
April 27, 2018: Revista Española de Enfermedades Digestivas
José Lariño-Noia, Daniel de la Iglesia, Julio Iglesias-García, Manuel Macías, Aurelio López Martín, María Luisa Legaz, Juan Vila, Antonio Reyes, Ihab Abdulkader, J Enrique Domínguez-Muñoz
INTRODUCTION: the incidence of cystic pancreatic lesions (CPL) in the asymptomatic population is increasing. Achieving a preoperative diagnosis of CPL still remains a challenge. OBJECTIVES: to evaluate the diagnostic accuracy of the cytological diagnosis of CPL from samples obtained by cytology brush versus standard endoscopic ultrasound fine needle aspiration (EUS-FNA). METHODS: a multicenter, randomized, open-label trial was performed of EUS-cytology brush (EUS-EB) versus EUS-FNA for the cytological diagnosis of CPL...
April 24, 2018: Revista Española de Enfermedades Digestivas
Fernando Geijo Martínez, Ana Sánchez Garrido, Héctor Marcos Prieto, Concepción Piñeiro Pérez, Ana Beatriz Prieto Bermejo, Alberto Álvarez Delgado, Antonio Velasco Guardado, Antonio Rodríguez Pérez
BACKGROUND: constipation-predominant irritable bowel syndrome (C-IBS) is a prevalent, complex and multifactorial disorder that represents a challenge in terms of diagnosis and therapeutic management. OBJECTIVE: to evaluate the effectiveness, safety and treatment satisfaction of linaclotide in C-IBS patients. METHODS: prospective, single-center and observational study conducted in patients diagnosed with C-IBS. The patients were treated with linaclotide (Constella®, Allergan Inc...
April 24, 2018: Revista Española de Enfermedades Digestivas
Iago Justo, Alberto Marcacuzco, Oana-Anisa Nutu, Alejandro Manrique, Jorge Calvo, Óscar Caso, Félix Cambra, Álvaro García-Sesma, Luis Carlos Jiménez-Romero
INTRODUCTION: gallbladder cancer is the most common biliary neoplasm and the sixth most common tumor of the digestive system. The disease has an ominous prognosis, with a 5-year survival rate of approximately 5%. It is usually diagnosed late and surgical resection is the only potential cure. METHODS: a retrospective study was carried out in 92 patients with a pathological diagnosis of gallbladder cancer from January 2000 to January 2016. RESULTS: the mean age of cases was 72 ± 11 years; 64 subjects were females and 28 were males...
April 24, 2018: Revista Española de Enfermedades Digestivas
Pablo Ercoli, Belinda García, Enrique Del Campo, Sergio Pinillos
We report the case of a previously healthy 2-year-old child who presented with significant abdominal distension. After several interventions that proved ineffective, pathologic aerophagia was eventually diagnosed. In pediatrics, pathologic aerophagia is an uncommon disorder that almost exclusively affects children with an underlying neurological condition. It may lead to multiple diagnostic tests and unnecessary aggressive therapies. A recent case report associated aerophagia with a novel concept of abdomino-phrenic dyssynergia...
April 24, 2018: Revista Española de Enfermedades Digestivas
Eduardo Rodrigues-Pinto, Pedro Pereira, Todd H Baron, Guilherme Macedo
BACKGROUND: self-expandable metal stents are often used for the palliative treatment of dysphagia in patients with advanced esophageal cancer and an anticipated limited survival. Due to previous reports of a high rate of adverse event when used long-term, concerns have been raised with regard to the use of self-expandable metal stents in patients with a longer survival. AIM: assess the role of esophageal self-expandable metal stents in patients with advanced esophageal cancer that have survived longer than six months...
April 24, 2018: Revista Española de Enfermedades Digestivas
María Sánchez Azofra, Miriam Romero Portales, Lucia Tortajada Laureiro, Javier García-Samaniego, Pedro Mora Sanz
Hepatitis E virus (HEV) infection is an emerging disease in developed countries with a broad clinical spectrum. In the absence of immunodeficiency or pregnancy, it is a mild and almost asymptomatic condition in most cases. However, extrahepatic manifestations, including neurological conditions, are common and may occasionally lead to permanent neurological sequelae. Herein, we report the case of an immunocompetent patient who was admitted to our hospital with paresthesia and weakness in both the upper extremities associated with anicteric-elevated transaminases...
April 24, 2018: Revista Española de Enfermedades Digestivas
Jesús García-Cano, Miriam Viñuelas Chicano, María Del Moral Martínez, Marta Muñiz Muñoz, Claudio Murillo Matamoros, Miguel Suárez Matías, Laura Valiente González, Teresa Martínez Pérez, Raquel Martínez Fernández, Carmen Julia Gómez Ruiz, José Ignacio Pérez García, Julia Morillas Ariño
INTRODUCTION: the guidewire (GW) may enter the pancreatic duct during common bile duct (CBD) cannulation attempts in endoscopic retrograde cholangiopancreatography (ERCP). After GW passage into the pancreas, the most effective maneuver for CBD cannulation and pancreatitis prevention has not been determined. AIM: to study CBD cannulation and post-ERCP pancreatitis rates when a pancreatic stent is inserted after an unintentional GW cannulation of the pancreatic duct...
April 24, 2018: Revista Española de Enfermedades Digestivas
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