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Revista Española de Enfermedades Digestivas

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https://www.readbyqxmd.com/read/28776388/gastroenterology-a-historical-specialty-with-a-great-future
#1
Javier Crespo, Francisco Jorquera Plaza
The specialty of gastroenterology (SGI) deals with the conditions involving the gut (esophagus, stomach, bowels, anorectal region), liver, bile ducts, pancreas, and peritoneum, specifically with their etiology, epidemiology, pathophysiology, semiology, diagnosis, prognosis, prevention, and treatment. As shown by Dr. Curbelo et al. in the present issue of the Spanish Journal of Digestive Diseases (Revista Española de Enfermedades Digestivas), our SGI has progressively grown as a specialty training option, and is now one of the five most commonly requested residency programs...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776387/the-baveno-vi-criteria-for-predicting-esophageal-varices-validation-in-real-life-practice
#2
Mafalda Sousa, Sónia Fernandes, Luísa Proença, Ana Paula Silva, Sónia Leite, Joana Silva, Ana Ponte, Jaime Rodrigues, João Carlos Silva, João Carvalho
BACKGROUND AND AIMS: According to the Baveno VI consensus, patients with liver stiffness < 20 kPa and a platelet count > 150,000 ul have very low risk of clinically significant varices and do not need a screening endoscopy. The aim of this study was to evaluate non-invasive methods as predictors of esophageal varices according to the Baveno VI recommendations, in real life clinical practice. METHODS: Retrospective evaluation of patients with chronic liver disease who underwent transient elastography between January 2013 and December 2015...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776386/post-transfusion-hyperhemolysis-syndrome-following-gastrointestinal-bleeding-secondary-to-prehepatic-portal-hypertension
#3
María de Los Ángeles Mejías Manzano, Álvaro Giráldez Gallego, Yolanda María Sánchez Torrijos
Supportive transfusion represents a basic tool in the management of gastrointestinal (GI) bleeding. However, the use of hemoderivatives is not exempt from risks such as development of hemolysis. We report a case of post-transfusion hyperhemolysis syndrome in a female patient with prehepatic portal hypertension.
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776385/sternal-cutaneous-metastasis-of-hilar-cholangiocarcinoma
#4
Antonio José Fernández López, María Encarnación Tamayo-Rodríguez, María Ángeles Paniza-Mendoza
Subcutaneous metastasis is a rare initial manifestation of visceral tumors, and represent advanced stages with poor prognosis. We report the case of a female patient with a subcutaneous nodule over the sternum, which was ultimately found to be a metastasis of hilar cholangiocarcinoma. Only 20 cases of subcutaneous metastasis from Klatskin tumors have been reported - a rare occurrence with poor survival rates.
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776384/a-case-of-a-mixed-adenoneuroendocrine-tumor-of-the-colon
#5
Joana Ribeiro da Silva, Rolando Taveira Pinho, Antonia Furtado
Neuroendocrine cells often coexist with exocrine neoplasms of the gut and each component is normally present in a variable range. Despite this frequent association, mixed exocrine-neuroendocrine carcinomas are rare. This entity is known as adenoneuroendocrine carcinoma (MANEC) and each of its malignant components represents at least 30%. In contrast, there are only a few reports of another rare association of an adenoma and a well differentiated neuroendocrine tumor (NET) in the colon and rectum. The term mixed adenoneuroendocrine tumor (MANET) was suggested due to its indolent behavior and distinct morphological characteristics with mild to moderate nuclear atypia and low number of mitoses1...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776383/hepatocellular-carcinoma-in-patients-without-advanced-fibrosis-after-eradication-of-hcv-with-antiviral-treatment
#6
Yolanda Sánchez-Torrijos, Jara Eloísa Ternero Vega, Carmen Cepeda Franco
From the last few years, hepatitis C virus and the new direct antiviral treatments are being more and more important. In consequence, case studies like the one we present, the appearance of hepatocelullar carcinoma after its eradication with fibrosis grade 2, are getting special interest. In 2007, our patient was treated with pegylated interferon α-2a and ribavirin, having a sustained virological response after it. In this way, liver fibrosis grade 2 was confirmed by a biopsy. Finally, after corroborating a good liver functioning, the patient was discharged (as, according to the guidebooks, an ultrasound scan of screeing every 6 months was not required)...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776382/neuroendocrine-tumors-of-the-pancreas-keys-issues-in-dealing-with-heterogeneity
#7
Javier A-Cienfuegos, Fernando Rotellar, Miguel Ruiz-Canela
Dear Enrique, I enclose the letter to reply the commenting letter of Modesto Varas. I thought appropiate to reply, in accordance with your proposal. It took me a bit to response because Modesto's letter is quite confusing, but I think positive to have letters on the Journal. If you consider opportune to comment on it, please don't hesitate to let me know. Thank you so much.
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776381/insulin-resistance-and-the-metabolic-syndrome-are-related-to-the-severity-of-steatosis-in-the-pediatric-population-with-obesity
#8
Esther Ubiña-Aznar, Leopoldo Tapia-Ceballos, José Miguel Rosales-Zabal, Rocío Porcel-Chacón, Francisco Poveda-Gómez, Carmen Lozano-Calero, Carmen Ortiz-Cuevas, Francisco Rivas-Ruiz, Andrés Sánchez Cantos, José María Navarro Jarabo
BACKGROUND: To determine the factors associated with an increased risk for severe steatosis (SS) and establish the Homeostatic Model Assessment-Insulin Resistance (HOMA-IR) as a screening tool. METHODS: A cross-sectional study was performed in obese children to assess the relationship between the metabolic syndrome (MetS) and glucose metabolism alterations (GMA) and the risk for severe steatosis. RESULTS: A total of 94 children (51 males) aged from six to 14 years were included...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776380/is-cholecystectomy-the-treatment-of-choice-for-acute-acalculous-cholecystitis-a-systematic-review-of-the-literature
#9
Víctor Soria Aledo, Lorena Galindo Iñíguez, Diego Flores Funes, Milagros Carrasco Prats, Jose Luis Aguayo Albasini
BACKGROUND AND OBJECTIVES: There is currently no consensus with regard to the use of cholecystectomy or percutaneous cholecystostomy as the therapy of choice for acute acalculous cholecystitis. The goal of this study was to review the scientific evidence on the management of these patients according to clinical and radiographic findings. METHODS: A systematic review of the literature from 2000 to 2016 was performed. The databases of PubMed, Índice Médico Español, Cochrane Library and Embase were searched according to the following inclusion criteria: publication language (English or Spanish), adult patients, acalculous etiology and appropriate study design...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776379/evolution-of-the-incidence-of-inflammatory-bowel-disease-in-southern-spain
#10
Federico Argüelles-Arias, Dina Chaaro Benallal, Jose Manuel Benítez, Raúl Perea Amarillo, Eva Iglesias, Luisa Castro Laria, Valle Sánchez García, María Belen Maldonado Pérez, Ángel Vilches, Ángel Caunedo Álvarez, Manuel Romero Gómez
BACKGROUND: The incidence of inflammatory bowel disease is increasing in Europe and in Spain. However, there is no recent data from Southern Spain. OBJECTIVES: To determine the evolution of the hospital incidence of inflammatory bowel disease in Southern Spain. MATERIAL AND METHODS: A retrospective study was performed in two hospitals in Southern Spain. Data was collected from inflammatory bowel disease patients, divided into two periods (1995-2000 and 2001-2014) and compared...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776378/colonic-diverticulosis-and-the-metabolic-syndrome-an-association
#11
Cristina Teixeira, Daniel Trabulo, Suzane Ribeiro, Cláudio Rodrigues Martins, Ana Luísa Alves, Isabelle Cremers, Ana Paula Oliveira
BACKGROUND AND OBJECTIVES: Colonic diverticulosis (CD) is related to advanced age and a lack of dietary fiber. Recently, several studies have shown that metabolic syndrome (MS) is also implicated in the etiopathogenesis of CD. This study aimed to assess the association between MS, obesity and CD. METHODS: This was a prospective study of a one-year duration. The MS was defined according to the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III)...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747060/treatment-persistence-during-therapeutic-sequences-with-adalimumab-and-infliximab-in-the-treatment-of-crohn-s-disease
#12
Carlos Taxonera, Pilar Robledo, Antonio Rodriguez
BACKGROUND AND AIM: Tumor necrosis factor (TNF) inhibitors have demonstrated efficacy and safety in the treatment Crohn's disease (CD). However, the loss of response over time means that they are usually used sequentially. The aim of this study was to compare treatment persistence with different sequences of TNF inhibitors in patients with active luminal CD. METHODS: A Markov model (3-month cycles) was developed to simulate the therapeutic sequences of beginning biological treatment with infliximab or adalimumab, with a time horizon of three years...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747059/rectal-inflammatory-stenosis-secondary-to-chlamydia-trachomatis-a-case-report
#13
Luis Eduardo Pérez Sánchez, Moisés Hernández Barroso, Guillermo Hernández Hernández
The rectal inflammatory originated strictures constitute a rare cause of intestinal obstruction. We present a 30-year-old male patient with a history of HIV and protctitis caused by Chalmydia trachomatis and HSV-2, in which develops a low intestinal obstruction refractory to medical treatment. Surgery was performed with good clinical evolution. The medical treatment constitutes the fundamental basis of the therapy in these patients. Despite that, when fibrotic stenoses are not treatable medical or endoscopically, they often require surgical treatment...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747058/pancreatic-enzyme-replacement-therapy-in-cystic-fibrosis-dose-variability-and-coefficient-of-fat-absorption
#14
Joaquim Calvo-Lerma, Sandra Martínez-Barona, Etna Masip, Victoria Fornés, Carmen Ribes-Koninckx
OBJECTIVES: Pancreatic enzyme replacement therapy (PERT) remains a backbone in the nutritional treatment of cystic fibrosis. Currently, there is a lack of an evidence-based tool that allows dose adjustment. To date, no studies have found an association between PERT dose and fat absorption. Therefore, the aim of the study was to assess the influence of both the PERT dose and the variability in this dose on the coefficient of fat absorption (CFA). METHODS: This is a retrospective longitudinal study of 16 pediatric patients (192 food records) with three consecutive visits to the hospital over a twelve-month period...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747057/prevalence-risk-factors-and-response-to-treatment-of-extra-intestinal-manifestations-in-patients-with-inflammatory-bowel-disease
#15
María Hernández-Tejero, Alicia Granja Navacerrada, Pilar Bernal Checa, Rubén Piqué Becerra, Alicia Algaba García, Iván Guerra Marina, Francisco Javier García-Alonso, Mariano Syed, Fernando Bermejo
INTRODUCTION: Patients with inflammatory bowel disease can experience extra-intestinal manifestations that may cause significant morbidity. AIMS: To describe the prevalence, characteristics, treatment and evolution of extra-intestinal manifestations in inflammatory bowel disease patients treated in our hospital and to identify associated risk factors. METHODS: This was a retrospective, observational, case-control study. All inflammatory bowel disease patients with extra-intestinal manifestations were considered as cases and inflammatory bowel disease patients without extra-intestinal manifestations were considered as controls...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747056/fecal-transplantation-as-a-treatment-for-clostridium-difficile-infection-in-patients-with-ulcerative-colitis
#16
Marta Izquierdo Romero, Pilar Varela Trastoy, Alejo Mancebo Mata
Clostridium difficile (CD) infection is currently the most frequent etiology of nosocomial diarrhea. Besides, its incidence is progressively increasing in ambulatory patients. Inflammatory bowel disease (IBD) is a risk factor of CD infection itself, but also due to the regular immunosuppressive treatment used in these patients. At the present time, fecal transplantation (FT) is a safe and cost-effective alternative if the previous antibiotic treatments have failed. Similar outcomes between patients with IBD and general population have been reported...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747055/cytomegalovirus-cmv-associated-ischemic-colitis-in-an-immunocompetent-patient
#17
Ana Puerta, Pablo Priego, Julio Galindo
Cytomegalovirus (CMV) colitis is a common entity in immunocompromised patients, being rare among immunocompetent individuals. In addition, its association with ischemic colitis is unusual in both groups of population. Rectal bleeding might occur in both entities and, occasionally, urgent surgical treatment may be required, associating high morbility rates. We report one case of cytomegalovirus colitis associated with severe ischemic colitis in a non- immunocompromised patient with favourable response to conservative management with antiviral therapy...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747054/towards-the-centralization-of-digestive-oncologic-surgery-changes-in-activity-techniques-and-outcome
#18
Cristian Tebé, Roger Pla, Josep Alfons Espinàs, Julieta Corral, Elisa Puigdomenech, Josep Maria Borràs, Joan M V Pons, Mireia Espallargues
The objective of the present study was to examine changes in the activity, surgical techniques and results from the process of centralization of complex digestive oncologic surgery in 2005-2012 as compared to 1996-2000. A retrospective cohort study employing the minimum basic data set of hospital discharge (MBDSHD 1996-2012) from public centers in Catalonia (Spain) was performed. The population consisted of individuals aged > 18 who underwent digestive oncologic surgery (esophagus, pancreas, liver, stomach or rectum)...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747053/eluxadoline-in-the-treatment-of-diarrhea-predominant-irritable-bowel-syndrome-the-sepd-perspective
#19
Isabel Vera, F Javier Júdez
Functional gut disorders, including diarrhea-predominant irritable bowel syndrome, are highly prevalent conditions worldwide that significantly impact health economy and patient quality of life, yet lacking fully satisfactory therapeutic options. These circumstances fostered research on various molecules with more specific therapeutic targets, including opioid receptors. Eluxadoline (Allergan's Vibercy® in the USA, Truberzi® in Europe) is a locally-acting mixed - and -opioid receptor agonist, and -opioid receptor antagonist, that was licensed in 2015 by the Food and Drug Administration (FDA) and in 2016 by the European Medicines Agency (EMA) for use in diarrhea-predominant irritable bowel syndrome...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28747052/diagnostic-and-therapeutic-features-of-small-bowel-involvement-in-portal-hypertension
#20
Juan Egea Valenzuela, Tania Fernández Llamas, Ana Victoria García Marín, Fernando Alberca de Las Parras, Fernando Carballo Álvarez
Enteropathy is a lesser known complication of portal hypertension and consists of different changes in the mucosal layer of the small bowel which lead to the appearance of vascular and inflammatory lesions. It can be an important co-factor in the development of anemia in the cirrhotic population, and nowadays an easy and non-invasive diagnosis can be made thanks to capsule endoscopy. However, it is rarely considered in the management of patients with portal hypertension. Some aspects such as pathogenesis or incidence remain unclear and no specific recommendations are included in the guidelines regarding diagnosis or treatment...
July 27, 2017: Revista Española de Enfermedades Digestivas
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