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International Journal of Impotence Research

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https://www.readbyqxmd.com/read/28904397/study-of-the-link-between-dopamine-transporter-gene-polymorphisms-and-response-to-paroxetin-and-escitalopram-in-patients-with-lifelong-premature-ejaculation
#1
T K Eltonsi, T M Tawfik, L A Rashed, S F GamalEl Din, M A Mahmoud
We evaluated the role of dopamine (DA) transporter gene polymorphism in lifelong premature ejaculation (LPE) and its role in determining the response to paroxetine and escitalopram. Eighty consecutive patients and controls were recruited. Sixty of them suffered from LPE. They were divided into two equal groups. One group received paroxetine 20 mg daily for 3 months and the other one received ecistalopram 20 mg daily for 3 months. Their wives were instructed to measure the intra-vaginal ejaculation latency time using stopwatch...
September 14, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28835714/surgical-outcomes-from-limiting-the-use-of-nonabsorbable-suture-in-tunica-albuginea-plication-for-peyronie-s-disease
#2
D Papagiannopoulos, J Phelps, E Yura, L A Levine
Tunica albuginea plication (TAP) surgery for Peyronie's disease (PD) is classically described using nonabsorbable suture. Many patients are aware of nodularity at the suture sites (50-88%), and some find them painful (10-33%). We explore whether limiting permanent sutures provides a durable correction of curve and report the incidence of bothersome nodules. Beginning in 2007, we modified our TAP procedure to limit the use of permanent sutures. We reviewed all patients who underwent TAP procedures from 2007 to 2014 at our institution...
August 24, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28814813/sexual-dysfunction-among-diabetics-and-its-impact-on-the-sqol-of-their-partners
#3
W K B A Owiredu, H Alidu, N Amidu, C Obirikorang, C K Gyasi-Sarpong, A T Bawah, P P M Dapare, A T Luuse
Sexual dysfunction (SD) has long been known to affect a significant number of people worldwide with serious implications and limitations on sexual expression and fulfillment. This may affect the sexual quality of life (SQoL) of individuals and their partners. A cross-sectional study was conducted among diabetic patients and their partners who visited the Tema General Hospital. A total of 130 and 116 diabetic males and females and their partners were interviewed. Male and female diabetic participants and partners were evaluated using the Golombuk Rust Inventory for Sexual Satisfaction-Male (GRISS-M)/SQoL-M and GRISS-Female/SQoL-F, respectively...
August 17, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28814812/transurethral-resection-of-the-prostate-turp-vs-greenlight-photoselective-vaporization-of-benign-prostatic-hyperplasia-analysis-of-bph6-outcomes-after-1-year-of-follow-up
#4
S Cimino, S Voce, F Palmieri, V Favilla, T Castelli, S Privitera, R Giardina, G Reale, G I Russo, G Morgia
The surgical treatment of benign prostatic obstruction is changing over the time, thanks the increase evidence about the successful role of laser techniques in this surgery. We aimed to compare prostatic GreenLight photovaporization (PVP) to bipolar transurethral resection of the prostate (TURP) with regard to lower urinary tract symptoms (LUTS) improvement through the evaluation of BPH6. We enrolled 220 consecutive subjects affected by LUTS. We performed a propensity score matching using prostate volume, peak flow and International Prostate Symptoms Score (IPSS)...
August 17, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28794519/the-effects-of-mirna-145-on-the-phenotypic-modulation-of-rat-corpus-cavernosum-smooth-muscle-cells
#5
J Luo, L Liu, Z Wu, G Chen, E Li, L Luo, F Li, S Zhao, A Wei, Z Zhao
To investigate the effect of miR-145 on the phenotypic modulation in rat corpus cavernosum smooth muscle cells. Corpus cavernosum smooth muscle cells were treated with either miR-145 mimics or miR-145 negative control. Cell proliferation were analyzed by the MTS assay and colony formation assay. Wound healing assay were performed to detect the effect of miR-145 on cell migration. The mRNA and protein levels of phenotype marker proteins were assessed by quantitative real-time polymerase chain reaction and western blotting...
August 10, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28747647/delivery-of-intracavernosal-therapies-using-needle-free-injection-devices
#6
D O'Kane, L Gibson, J du Plessis, A Davidson, D Bolton, N Lawrentschuk
ED affects a significant proportion of males worldwide. With an ever-aging population the prevalence of ED is predicted to double in the next decade. Oral PDE-5 inhibitors are the first-line treatment for ED and have revolutionised its management. These agents are however ineffective in some men. Intracavernosal injection (ICI) of vasoactive agents is an effective second-line therapy for ED. Despite proven efficacy, needle phobia and anxiety with self-needling limit the use of intracavernosal (IC) therapies...
July 27, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28701798/cognitive-behavioral-therapy-as-an-adjunct-treatment-for-pakistani-men-with-ed
#7
S Khan, A Amjad, D Rowland
The goal of this study was to determine potential positive effects of cognitive behavioral therapy (CBT) on Pakistani men with ED who were undergoing treatment with a PDE-5 inhibitor. We used a pre-post research design comparing men with and without adjunctive CBT. Men in the two groups were compared to determine whether CBT improved sexual function, as measured by the International Index of Erectile Function (IIEF). A total of 60 individuals diagnosed with ED completed the study. Participants were systematically assigned to one of two groups, the CBT group or the control group...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28659632/assessment-of-erectile-dysfunction-and-associated-psychological-distress-in-chinese-men-with-type-2-diabetes-mellitus
#8
S Chen, D Peng, X Xu, J Gao, F Dai, C Zuo, Q Zhang
To estimate the prevalence of erectile dysfunction (ED) and the level of psychological distress and to assess the inter-associations of them among type 2 diabetic men, a cross-sectional observational study of 335 men with type 2 diabetes and 284 men without diabetes from a hospital in Hefei city, Anhui province, China, was conducted. The erectile function was assessed using the five-item version of the International Index of Erectile Function scale (IIEF-5). The evaluation of psychological distress was completed using a self-administered questionnaire, the Symptom Checklist 90-Revised (SCL-90-R)...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28659631/a-retrospective-analysis-of-risk-factors-for-ipp-reservoir-entry-into-the-peritoneum-after-abdominal-wall-placement
#9
M S Gross, D S Stember, B B Garber, P E Perito
Placement of an inflatable penile prosthesis (IPP) is the most effective treatment modality for men with ED refractory to medical management. We have previously demonstrated a protocol for IPP reservoir placement within the abdominal wall musculature, which was shown to be a safer location than traditional placement in the retropubic space of Retzius. The aim of this study was to review our complications with IPP reservoir entry into the peritoneum after abdominal wall placement of the reservoir. We retrospectively reviewed our two patients with peritoneal entry of the reservoir after posterior to transversalis fascia and anterior to transversalis fascia placement during virgin and compromised IPP cases, respectively...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28659630/relationship-between-sexual-position-and-severity-of-penile-fracture
#10
R Barros, L Schulze, A A Ornellas, L Koifman, L A Favorito
The objective of the study was to evaluate the relationship between the sexual position and severity of penile fracture (PF). We studied 90 patients with PF. The mechanism of injury and the sexual position was assessed. We divided our sample by the etiology of the fracture in six groups: (a) masturbation or penile manipulation; (b) 'man-on-top' position; (c) 'doggy style' position; (d) 'woman-on-top' position; (d) blunt trauma; and (e) 'rolling over' fracture. We used the χ(2)-test for contingency analysis of the populations under study (P<0...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28539643/myostatin-a-profibrotic-factor-and-the-main-inhibitor-of-striated-muscle-mass-is-present-in-the-penile-and-vascular-smooth-muscle
#11
I Kovanecz, M Masouminia, R Gelfand, D Vernet, J Rajfer, N F Gonzalez-Cadavid
Myostatin is present in striated myofibers but, except for myometrial cells, has not been reported within smooth muscle cells (SMC). We investigated in the rat whether myostatin is present in SMC within the penis and the vascular wall and, if so, whether it is transcriptionally expressed and associated with the loss of corporal SMC occurring in certain forms of erectile dysfunction (ED). Myostatin protein was detected by immunohistochemistry/fluorescence and western blots in the perineal striated muscles, and also in the SMC of the penile corpora, arteries and veins, and aorta...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28469181/expression-and-distribution-of-the-transient-receptor-potential-cationic-channel-a1-trpa1-in-the-human-clitoris-comparison-to-male-penile-erectile-tissue
#12
S Ückert, K Albrecht, A Bannowsky, M Sohn, M A Kuczyk, P Hedlund
The transient receptor potential cationic channel ankyrin 1 (TRPA1) is a channel protein assumed to act in various human tissues as mechano- and pain sensor and play a role in neurotransmission. The expression of TRPA has already been investigated in the human prostate and urethra, however, only very few studies have addressed the expression and distribution in the male and female genital tract. The present study aimed to investigate by means of immunohistochemistry (double-labeling technique, laser fluorescence microscopy) in the human clitoris and penile erectile tissue the localization of TRPA1 in relation to nNOS, the vasoactive intestinal polypeptide (VIP) and vesicular acetylcholine transporter (VAChT)...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424506/long-term-outcomes-of-ams-spectra%C3%A2-penile-prosthesis-implantation-and-satisfaction-rates
#13
F Akdemir, E Okulu, Ö Kayıgil
The aim of this study was to evaluate the surgical implantation techniques of AMS Spectra malleable penile prosthesis, its intraoperative and postoperative complications, and the rates of patient and partner satisfaction. Forty-six patients on whom AMS Spectra malleable penile prosthesis implantation was performed between 2009 and 2014 were retrospectively examined. Any complications seen intraoperatively and postoperatively were determined. International Index of Erectile Function (IIEF)-5, total IIEF erectile function domain scores were calculated preoperatively...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424505/usefulness-of-serum-fetuin-a-level-as-a-marker-of-erectile-dysfunction
#14
W Kandeel, W El-Shaer, A Sebaey, A A Abou-Taleb, A Fathy, B Elmohamady, A I Mansour
This study aimed to evaluate the correlation between serum levels of fetuin-A and the presence and severity of erectile dysfunction (ED) in Egyptian population. The study was performed on 60 ED patients and 20 age-matched healthy controls. A comprehensive medical history and complete physical examination were obtained and performed in all participants. ED and its severity were assessed via International Index of Erectile Function (IIEF-5). Doppler ultrasound, fasting blood glucose level, complete lipid profile, serum total testosterone (TT) and serum fetuin-A were performed...
September 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28446800/oxidative-stress-evoked-damages-on-rat-sperm-and-attenuated-antioxidant-status-on-consumption-of-aspartame
#15
I Ashok, P S Poornima, D Wankhar, R Ravindran, R Sheeladevi
Although several studies on toxic effect of aspartame metabolite have been studied, controversial reports over the use of aspartame owing to the fact that it releases methanol as one of its metabolite during metabolism exist. This present study is proposed to investigate whether aspartame (40 mg kg(-1) b.wt) administration for 90 days could induce oxidative stress and alter antioxidant status of epididymal sperm in Wistar strain male albino rats. To mimic the human methanol metabolism, methotrexate (MTX)-treated rats were included to study the effects of aspartame...
July 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424503/sexuality-education-in-japanese-medical-schools
#16
M Shirai, A Tsujimura, A Abdelhamed, S Horie
The present study aimed to investigate current sexuality education in Japanese medical schools and the impact of position title in the Japanese Society for Sexual Medicine (JSSM). Questionnaires were mailed to urology departments in all Japanese medical schools. The responses were evaluated according to four factors: the number of lecture components, curriculum hours, degree of satisfaction with the components and degree of satisfaction with the curriculum hours. We also investigated differences in these four factors among three groups: Directors, Council members and non-members of the JSSM...
July 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424502/significance-of-serum-endothelial-cell-specific-molecule-1-endocan-level-in-patients-with-erectile-dysfunction-a-pilot-study
#17
M Karabakan, A Bozkurt, S Akdemir, M Gunay, E Keskin
This study aimed to measure the serum endocan level of patients with erectile dysfunction (ED) and to investigate the possible association between the Endothelial-specific molecule-1 (Endocan) level and ED. Twenty healthy and sixty-four male patients included in the study were divided into four groups: severe ED (19 patients), moderate ED (24 patients), mild ED (21 patients) and control group (20 healthy men). The erectile function of all the patients was evaluated using the International Index of Erectile Function-5 (IIEF-5) questionnaire...
July 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424501/translation-and-validation-of-the-greek-version-of-the-female-sexual-function-index-questionnaire
#18
A Zachariou, M Filiponi, P S Kirana
The clinical evaluation of female sexual dysfunctions should be supplemented by validated questionnaires; however, there is no specific instrument available in Greek language. The study was designed to linguistically validate the Greek version of Female Sexual Function Index (FSFI). Ninety-nine healthy women and eighteen women with a sexual dysfunction were recruited through a survey and were asked to voluntarily complete the FSFI questionnaire in Greek (FSFI-Gr) at baseline and after 2 weeks. We assessed validity, internal consistency reliability and test-retest reliability of the FSFI greek version...
July 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424500/percutaneous-transluminal-coronary-angioplasty-for-acute-myocardial-infarction-the-impact-on-sexual-function-in-men
#19
C Goławski, M Dłużniewski, E Kostarska-Srokosz, K Nowosielski, J Syska-Sumińska, M Chmielewski, R Kowalczyk
The aim of this study was to evaluate changes in men's sexual function after percutaneous transluminal coronary angioplasty (PTCA) treatment for acute myocardial infarction (MI). Sixty men aged 18-70 years old were included in the study. All patients had acute MI and underwent PTCA. They underwent two post PCTA visits: 3 days and between 4 and 6 months after PTCA. During the first and second visit a standard medical interview was carried out and sexual function data collected using Changes in Sexual Functioning Questionnaire and International Index of Erectile Function (IIEF-15)...
July 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28424499/tamsulosin-for-treatment-of-lower-urinary-tract-symptoms-in-women-a-systematic-review-and-meta-analysis
#20
H L Zhang, Z G Huang, Y Qiu, X Cheng, X Q Zou, T T Liu
Tamsulosin has been used for the off-label treatment of lower urinary tract symptoms (LUTS) in women. Over the past few years, several randomized controlled trials (RCTs) have reported the clinical effectiveness and safety of tamsulosin for LUTS in women. Therefore, the aim of the present study was to perform a meta-analysis to evaluate the safety and efficacy of tamsulosin in treating LUTS in women, which may resolve some of the current controversies over use of the drug and provide more reliable evidence for the use of tamsulosin...
July 2017: International Journal of Impotence Research
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