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Current Opinion in Obstetrics & Gynecology

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https://www.readbyqxmd.com/read/28520585/the-role-of-simulation-and-warm-up-in-minimally-invasive-gynecologic-surgery
#1
Janelle K Moulder, Michelle Louie, Tarek Toubia, Lauren D Schiff, Matthew T Siedhoff
PURPOSE OF REVIEW: The purpose of the review is to update the reader on the current literature and recent studies evaluating the role of simulation and warm-up as part of surgical education and training, and maintenance of surgical skills. RECENT FINDINGS: Laparoscopic and hysteroscopic simulation may improve psychomotor skills, particularly for early-stage learners. However, data are mixed as to whether simulation education is directly transferable to surgical skill...
May 16, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28448277/long-term-consequences-of-obesity-on-female-fertility-and-the-health-of-the-offspring
#2
Suchitra Chandrasekaran, Genevieve Neal-Perry
PURPOSE OF REVIEW: Obesity has reached near epidemic levels among reproductive age women with a myriad of consequences. Obesity adversely affects the maternal milieu by creating conditions that decrease fertility and increase the risk of gestational diabetes, hypertensive disease in pregnancy, fetal growth abnormalities and congenital anomalies. The effects of obesity are not limited to pregnancy. Indeed, beyond the immediate postpartum period, obese women maintain a higher prevalence of insulin resistance and cardiovascular disease...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28410349/zika-virus-and-assisted-reproduction
#3
Christina N Cordeiro, Rashda Bano, Chantel I Washington Cross, James H Segars
PURPOSE OF REVIEW: Due to the fact that the Zika virus can be sexually transmitted, there is a potential risk for disease transmission at several stages of assisted reproduction. Such a possibility poses a serious challenge to couples pursing fertility with reproductive technologies. Here, we discuss what is known regarding Zika virus infection with respect to sexual transmission and correlate this knowledge with recent recommendations in the realm of infertility treatment. RECENT FINDINGS: Zika virus can be transmitted from infected men and women through vaginal, oral or anal intercourse...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28362681/dual-ovarian-stimulation-and-random-start-in-assisted-reproductive-technologies-from-ovarian-biology-to-clinical-application
#4
Alberto Vaiarelli, Roberta Venturella, Damiano Vizziello, Francesco Bulletti, Filippo M Ubaldi
PURPOSE OF REVIEW: The opportunity to use gonadotropins to stimulate the growth of antral follicles coming from different follicular waves available in different moment of the menstrual cycle allowed the implementation of innovative protocols in assisted reproductive technologies. The purpose of this review is to explore the possible advantages related to these new controlled ovarian stimulation (COS) strategies. RECENT FINDINGS: Women exhibit major and minor wave patterns of ovarian follicular development during the menstrual cycle, as it is in animal species...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28362680/telemonitoring-in-ivf-icsi
#5
Jan Gerris
PURPOSE OF REVIEW: Traditionally, ovarian stimulation for IVF/intracytoplasmic sperm injection is performed by healthcare professionals, requiring the patient to make frequent visits to these centres. We describe the rationale, research findings and early clinical experience with home-based sonography for IVF patients. RECENT FINDINGS: Published experience indicates that selected patients are able to procure video sequences themselves; they value the empowerment, discretion and decreased stress involved in these visits; partner involvement increases as well...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28333696/a-universal-freeze-all-strategy-why-it-is-not-warranted
#6
Baris Ata, Emre Seli
PURPOSE OF REVIEW: There's some preclinical evidence of an adverse effect of multifollicular growth on endometrial function in assisted reproductive technology cycles. Universal elective frozen embryo transfer (eFET) in an unstimulated cycle is being promoted as a panacea, regardless of patient, and cycle characteristics. We review the clinical evidence on the effectiveness and safety of eFETs. RECENT FINDINGS: Randomized controlled trials (RCTs) comparing fresh and eFET yield contradictory results in terms of live birth rates...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28306561/diving-into-the-oocyte-pool
#7
Stine G Kristensen, Susanne E Pors, Claus Y Andersen
PURPOSE OF REVIEW: The ovarian reserve comprises an enormous surplus of follicles. Despite this, some women produce insufficient numbers of oocytes by conventional fertility treatments. However, recent technical accomplishments may transform assisted reproductive technology (ART) in such a way that oocytes are not necessarily the limiting factor. In this review, we present possible new strategies for enhancing the quantity of mature oocytes, and current views on autologous oocytes as potential sources of mitochondria to lift performance of compromised oocytes...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28306560/growth-hormone-in-ivf-cycles-any-hope
#8
Roger J Hart, Luk Rombauts, Robert J Norman
PURPOSE OF REVIEW: Growth hormone (GH) has been used as an adjunct in ovulation induction and IVF for 25 years, particularly as an adjunct to ovarian stimulation for women who had a previous poor response to stimulation in an IVF cycle. It does not have US Food and Drug Administration approval for this use. Unfortunately, due to the problems inherent with recruiting women who have undergone unsuccessful IVF treatment cycles and their inevitable low live birth rate per initiated cycle, many studies performed to date have been underpowered...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28266934/preimplantation-embryonic-mosaicism-origin-consequences-and-the-reliability-of-comprehensive-chromosome-screening
#9
Diego Marin, Richard T Scott, Nathan R Treff
PURPOSE OF REVIEW: Embryonic mosaicism represents an ongoing challenge for contemporary comprehensive chromosome screening platforms due to the unknown reproductive potential of mosaic embryos and technical difficulties of its detection from a single embryo biopsy. RECENT FINDINGS: Mosaicism in preimplantation embryos is a product of mitotic errors arising primarily from anaphase lag and chromosome nondisjunction. To date, there is high variability among estimations of prevalence of mosaicism in blastocysts, the most recent ranging from 3...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28266933/endometrial-microbiome
#10
Jason M Franasiak, Richard T Scott
PURPOSE OF REVIEW: There have been great improvements in assisted reproduction in the recent decade; however, there are still a significant number of chromosomally normal blastocysts that fail to produce live births. The human microbiome is the totality of the microbes and their genomes that exist in and on the host. The understanding of its impact on health and human disease, particularly in human reproduction, is evolving. RECENT FINDINGS: New technologies have empowered metagenomic sample analysis that allows for more fully characterizing the reproductive tract microbiome...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28266932/should-we-forget-about-embryos-till-day-5
#11
Fernando Bronet, David Agudo
PURPOSE OF REVIEW: To find the way of having more and better blastocyst is essential. How to culture embryos up to blastocyst stage remains critical. RECENT FINDINGS: Several studies show how a blastocyst score can predict the implantation potential. If that score is enough to choose the best blastocyst, as culture conditions would not be affected in these days, we would not need to check early cleavage embryos, even it could be better for the embryo development...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28234769/perinatal-outcomes-after-oocyte-donation-and-in-vitro-fertilization
#12
Mohan S Kamath, Sesh K Sunkara
PURPOSE OF REVIEW: To critically appraise the existing literature on perinatal outcomes following oocyte donation (OD) pregnancies and compare it with autologous in-vitro fertilization (IVF) pregnancies. RECENT FINDINGS: OD pregnancies are at higher risk of developing hypertensive disorders compared with autologous IVF. The risk of preterm birth and low birth weight is higher with singleton and multiple OD compared with autologous IVF pregnancies. There is no increased risk of congenital malformations following OD compared with autologous IVF births...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28212156/impact-of-very-low-anti-m%C3%A3-llerian-hormone-on-pregnancy-success
#13
Alberto Pacheco, María Cruz, Juan Antonio García Velasco
PURPOSE OF REVIEW: Biomarkers are useful tool to help clinicians to estimate the chances of pregnancy of an infertile couple prior to assisted reproductive treatment. One proposed candidate is anti-Müllerian hormone (AMH), but its role as a predictor of reproductive success, especially in patients with low or very low levels, is under discussion. This review highlights recent findings from literature regarding to reproductive outcome in women with very low levels of AMH. RECENT FINDINGS: Although there is a general agreement about the lower pregnancy rates of patients with very low levels of AMH compared with patients with normal AMH levels, the role of AMH as a predictor of success is still under discussion...
June 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28253207/prenatal-diagnosis
#14
Jane Chueh
No abstract text is available yet for this article.
April 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28253206/invasive-therapies-for-primary-post-partum-haemorrhage-as-missed-opportunities-for-medical-prevention
#15
Gilles Kayem, Catherine Deneux-Tharaux
PURPOSE OF REVIEW: Examine the available results from population-based studies to test the hypothesis that differences between countries in medical practices for the management of labour, delivery and early bleeding may lead to a differential risk of post-partum haemorrhage (PPH)-related maternal morbidity and in the need for PPH-related invasive therapies. RECENT FINDINGS: International comparison of ratios of maternal mortality due to PPH shows significant differences between developed countries...
April 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28151755/renal-cystic-disease-and-associated-ciliopathies
#16
Karl O Kagan, Andreas Dufke, Ulrich Gembruch
PURPOSE OF REVIEW: To review disorders that are associated with renal cystic disease during prenatal life and to highlight the strong association between renal cystic disease and ciliopathies. RECENT FINDINGS: There are numerous causative genes for ciliopathies that can present with cystic kidney disease. In the group of single gene ciliopathies, autosomal dominant polycystic kidney disease is by far the most prevalent one. Other examples are autosomal recessive polycystic kidney disease, nephronophthisis, Bardet-Biedl syndrome, Meckel-Gruber syndrome, Joubert syndrome and related disorders as well as X-linked orofaciodigital syndrome type 1, respectively...
April 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28151754/maternal-risks-of-fetal-therapy
#17
Alyaa Al-Refai, Greg Ryan, Tim Van Mieghem
PURPOSE OF REVIEW: Although most fetal disorders can be treated after birth, a few conditions that predictably lead to fetal or neonatal death, or that progress significantly before birth, are ideally treated prenatally. The number of centers offering fetal therapeutic procedures is gradually increasing worldwide. Patients and caregivers should be aware of the potential maternal risks of these interventions. RECENT FINDINGS: For transplacental medical therapy (corticosteroids, antiarrhythmics and immunoglobulins), severe maternal adverse events are rare, when done in expert centers...
April 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28134671/maternal-fetal-medicine
#18
James F Smith
No abstract text is available yet for this article.
April 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28134670/noninvasive-prenatal-diagnosis-for-single-gene-disorders
#19
Stephanie Allen, Elizabeth Young, Benjamin Bowns
PURPOSE OF REVIEW: Noninvasive prenatal diagnosis for single gene disorders is coming to fruition in its clinical utility. The presence of cell-free DNA in maternal plasma has been recognized for many years, and a number of applications have developed from this. Noninvasive prenatal diagnosis for single gene disorders has lagged behind due to complexities of technology development, lack of investment and the need for validation samples for rare disorders. RECENT FINDINGS: Publications are emerging demonstrating a variety of technical approaches and feasibility of clinical application...
April 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28134669/prenatal-imaging-findings-in-fetal-zika-virus-infection
#20
Edward Araujo Júnior, Francisco H C Carvalho, Gabriele Tonni, Heron Werner
PURPOSE OF REVIEW: The aim of this review is to report the most recent observations concerning intrauterine Zika virus (ZIKV) infection and associated neuroimaging. RECENT FINDINGS: ZIKV outbreak in Brazil in 2015 was associated with an impressive registration of cases of congenital microcephaly in women with symptoms suggestive of ZIKV infection. Clinical and laboratory testing for ZIKV and hypothetic etiopathogenetic mechanisms are described. Diagnostic tests on blood, urine and amniotic fluid should be performed in all mothers with symptoms suggestive of intrauterine ZIKV infection...
April 2017: Current Opinion in Obstetrics & Gynecology
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