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HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery

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https://www.readbyqxmd.com/read/27847403/pancreatic-cancer-80-years-of-surgery-percentage-and-repetitions
#1
REVIEW
Birgir Gudjonsson
Objective. The incidence of pancreatic cancer is estimated to be 48,960 in 2015 in the US and projected to become the second and third leading causes of cancer-related deaths by 2030. The mean costs in 2015 may be assumed to be $79,800 per patient and for each resection $164,100. Attempt is made to evaluate the results over the last 80 years, the number of survivors, and the overall survival percentage. Methods. Altogether 1230 papers have been found which deal with resections and reveal survival information...
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/27803512/evaluation-of-early-cholecystectomy-versus-delayed-cholecystectomy-in-the-treatment-of-acute-cholecystitis
#2
Miguel Sánchez-Carrasco, Juan C Rodríguez-Sanjuán, Fernando Martín-Acebes, Francisco J Llorca-Díaz, Manuel Gómez-Fleitas, Rocío Zambrano Muñoz, F Javier Sánchez-Manuel
Objective. To evaluate if early cholecystectomy (EC) is the most appropriate treatment for acute cholecystitis compared to delayed cholecystectomy (DC). Patients and Methods. A retrospective cohort study of 1043 patients was carried out, with a group of 531 EC cases and a group of 512 DC patients. The following parameters were recorded: (1) postoperative hospital morbidity, (2) hospital mortality, (3) days of hospital stay, (4) readmissions, (5) admission to the Intensive Care Unit (ICU), (6) type of surgery, (7) operating time, and (8) reoperations...
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/27738384/intraoperative-fluid-excess-is-a-risk-factor-for-pancreatic-fistula-after-partial-pancreaticoduodenectomy
#3
Helge Bruns, Veronika Kortendieck, Hans-Rudolf Raab, Dalibor Antolovic
Background. After pancreaticoduodenectomy (PD), pancreatic fistulas (PF) are a frequent complication. Infusions may compromise anastomotic integrity. This retrospective analysis evaluated associations between intraoperative fluid excess and PF. Methods. Data on perioperative parameters including age, sex, laboratory findings, histology, infusions, surgery time, and occurrence of grade B/C PF was collected from all PD with pancreaticojejunostomy (PJ) performed in our department from 12/2011 till 02/2015. The glomerular filtration rate (GFR), infusion rate, and the ratio of both and its association with PF were calculated...
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/27418717/hepatectomy-based-on-future-liver-remnant-plasma-clearance-rate-of-indocyanine-green
#4
Yuichiro Uchida, Hiroaki Furuyama, Daiki Yasukawa, Hiroto Nishino, Yasuhisa Ando, Toshiyuki Hata, Takafumi Machimoto, Tsunehiro Yoshimura
Background. Hepatectomy, an important treatment modality for liver malignancies, has high perioperative morbidity and mortality rates. Safe, comprehensive criteria for selecting patients for hepatectomy are needed. Since June 2011, we have used a cut-off value of ≧ 0.05 for future liver remnant plasma clearance rate of indocyanine green as a criterion for hepatectomy. The aim of this study was to verify the validity of this criterion. Methods. From June 2011 to December 2015, 212 hepatectomies were performed in Tenri Yorozu Hospital...
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/27147813/extended-perioperative-antibiotic-coverage-in-conjunction-with-intraoperative-bile-cultures-decreases-infectious-complications-after-pancreaticoduodenectomy
#5
Amir H Fathi, Terence Jackson, Mehdi Barati, Babak Eghbalieh, Kelly A Siegel, Christopher T Siegel
Background. Bile contamination from the digestive tract is a well-known risk factor for postoperative complications. Despite the literature concerning prevalence of bacterobilia and fungobilia in patients with biliary pathologies, there are no specific recommendations for perioperative antimicrobial coverage for biliary/pancreatic procedures. We evaluated the effect of at least 72 hours of perioperative broad spectrum antibiotic coverage on outcomes of pancreaticoduodenectomy (PD). Materials and Methods. A retrospective review of all patients at Case Medical Center of Case Western Reserve University undergoing PD procedure, from 2006 to 2011, was performed (n = 122)...
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/27143815/quality-of-life-in-hepatocellular-carcinoma-patients-treated-with-transarterial-chemoembolization
#6
REVIEW
Saleem Ahmed, Nurun Nisa de Souza, Wang Qiao, Meidai Kasai, Low Jee Keem, Vishal G Shelat
Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers worldwide. Majority of patients with HCC are diagnosed in the advanced stages of disease and hence they are only suitable for palliative therapy. TACE (transarterial chemoembolization) is the most commonly used treatment for unresectable HCC. It is however unclear if TACE improves the quality of life (QoL) in patients with HCC. The aim of this review is to evaluate the impact of TACE on QoL of HCC patients.
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/27122655/diagnostic-laparoscopy-with-ultrasound-still-has-a-role-in-the-staging-of-pancreatic-cancer-a-systematic-review-of-the-literature
#7
REVIEW
Jordan Levy, Mehdi Tahiri, Tsafrir Vanounou, Geva Maimon, Simon Bergman
Background. The reported incidence of noncurative laparotomies for pancreatic cancer using standard imaging (SI) techniques for staging remains high. The objectives of this study are to determine the diagnostic accuracy of diagnostic laparoscopy with ultrasound (DLUS) in assessing resectability of pancreatic tumors. Study Design. We systematically searched the literature for prospective studies investigating the accuracy of DLUS in determining resectability of pancreatic tumors. Results. 104 studies were initially identified and 19 prospective studies (1,573 patients) were included...
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/26884642/the-role-of-eugenol-in-the-prevention-of-acute-pancreatitis-induced-acute-kidney-injury-experimental-study
#8
Charalampos Markakis, Alexandra Tsaroucha, Apostolos E Papalois, Maria Lambropoulou, Eleftherios Spartalis, Christina Tsigalou, Konstantinos Romanidis, Constantinos Simopoulos
Aim. Acute pancreatitis is an inflammatory intra-abdominal disease, which takes a severe form in 15-20% of patients and can result in high mortality especially when complicated by acute renal failure. The aim of this study is to assess the possible reduction in the extent of acute kidney injury after administration of eugenol in an experimental model of acute pancreatitis. Materials and Methods. 106 male Wistar rats weighing 220-350 g were divided into 3 groups: (1) Sham, with sham surgery; (2) Control, with induction of acute pancreatitis, through ligation of the biliopancreatic duct; and (3) Eugenol, with induction of acute pancreatitis and eugenol administration at a dose of 15 mg/kg...
2016: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/26663981/hepatocellular-carcinoma-in-the-pediatric-population-a-population-based-clinical-outcomes-study-involving-257-patients-from-the-surveillance-epidemiology-and-end-result-seer-database-1973-2011
#9
Christine S M Lau, Krishnaraj Mahendraraj, Ronald S Chamberlain
Introduction. Hepatocellular carcinoma (HCC) is a rare pediatric cancer accounting for 0.5% of all pediatric malignancies. This study examines a large cohort of HCC patients in an effort to define the factors impacting clinical outcomes in pediatric HCC patients compared to adults. Methods. Demographic and clinical data on 63,771 HCC patients (257 pediatric patients ≤ 19 and 63,514 adult patients age ≥ 20) were abstracted from the SEER database (1973-2011). Results. HCC was more common among males (59.5% pediatric and 75...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/26491217/preoperative-diagnostic-angiogram-and-endovascular-aortic-stent-placement-for-appleby-resection-candidates-a-novel-surgical-technique-in-the-management-of-locally-advanced-pancreatic-cancer
#10
N Trabulsi, J S Pelletier, C Abraham, T Vanounou
Background. Pancreatic adenocarcinoma of the body and tail usually presents late and is typically unresectable. The modified Appleby procedure allows resection of pancreatic body carcinoma with celiac axis (CA) invasion. Given that the feasibility of this technique is based on the presence of collateral circulation, it is crucial to confirm the presence of an anatomical and functional collateral system. Methods. We here describe a novel technique used in two patients who were candidates for Appleby resection...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/26457000/effect-of-the-human-amniotic-membrane-on-liver-regeneration-in-rats
#11
Mesut Sipahi, Sevinç Şahin, Ergin Arslan, Hasan Börekci, Bayram Metin, Nuh Zafer Cantürk
Introduction. Operations are performed for broader liver surgery indications for a better understanding of hepatic anatomy/physiology and developments in operation technology. Surgery can cure some patients with liver metastasis of some tumors. Nevertheless, postoperative liver failure is the most feared complication causing mortality in patients who have undergone excision of a large liver mass. The human amniotic membrane has regenerative effects. Thus, we investigated the effects of the human amniotic membrane on regeneration of the resected liver...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/26420916/the-surgical-management-of-concomitant-gallbladder-and-common-bile-duct-stones
#12
J H Darrien, K Connor, A Janeczko, J J Casey, S Paterson-Brown
Background. The management of choledocholithiasis has evolved from open common bile duct exploration (OCBDE) to therapeutic endoscopic retrograde cholangiopancreatography (ERCP) to laparoscopic common bile duct exploration (LCBDE). Each entails a degree of difficulty. Aim. To review 5-year results of bile duct exploration in an UGI unit. Methods. Common bile duct explorations (CBDEs) performed between January 2008 and January 2013 were identified from a prospectively collected clinical audit system and results reviewed retrospectively...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/26351405/feasibility-of-comparing-the-results-of-pancreatic-resections-between-surgeons-a-systematic-review-and-meta-analysis-of-pancreatic-resections
#13
REVIEW
Kurinchi Gurusamy, Clare Toon, Bhavisha Virendrakumar, Steve Morris, Brian Davidson
Background. Indicators of operative outcomes could be used to identify underperforming surgeons for support and training. The feasibility of identifying HPB surgeons with poor operative performance ("outliers") based on the results of pancreatic resections is not known. Methods. A systematic review of Medline, Embase, and the Cochrane library was performed to identify studies on pancreatic resection including at least 100 patients and published between 2004 and 2014. Proportions that lay outside the upper 95% and 99...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/26106254/assessment-of-liver-remnant-using-icg-clearance-intraoperatively-during-vascular-exclusion-early-experience-with-the-aliive-technique
#14
Lawrence Lau, Christopher Christophi, Mehrdad Nikfarjam, Graham Starkey, Mark Goodwin, Laurence Weinberg, Loretta Ho, Vijayaragavan Muralidharan
Background. The most significant risk following major hepatectomy is postoperative liver insufficiency. Current preoperative assessment of the future liver remnant relies upon assumptions which may not be valid in the setting of advanced resection strategies. This paper reports the feasibility of the ALIIVE technique which assesses the liver remnant with ICG clearance intraoperatively during vascular exclusion. Methods. 10 patients undergoing planned major liver resection (hemihepatectomy or greater) were recruited...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/25918455/the-changing-spectrum-of-surgically-treated-cystic-neoplasms-of-the-pancreas
#15
Jennifer K Plichta, Jacqueline A Brosius, Sam G Pappas, Gerard J Abood, Gerard V Aranha
Introduction. While the incidence of pancreatic cystic lesions has steadily increased, we sought to evaluate the changes in their surgical management. Methods. Patients with pancreatic cystic lesions who underwent surgical resection from 2003 to 2013 were identified. Clinicopathologic factors were analyzed and compared to a similar cohort from 1992 to 2002. Results. There were 134 patients with pancreatic cystic lesions who underwent surgical resection from 2003 to 2013, compared to 73 from 1992 to 2002. The most common preoperative imaging was a CT scan, although 66% underwent EUS and 63% underwent biopsy...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/25873753/surgery-for-cystic-pancreatic-lesions-in-the-post-sendai-era-a-single-institution-experience
#16
Jörg Kleeff, Christoph Michalski, Bo Kong, Mert Erkan, Susanne Roth, Jens Siveke, Helmut Friess, Irene Esposito
Introduction. The management of cystic pancreatic lesions has changed in recent years as a result of increasing knowledge of their biological behaviour, better diagnostic options, and international guidelines. Methods. Retrospective analysis of a cohort of 86 patients operated for cystic pancreatic lesions during a seven-year period (2007-2014). Results. Final histopathology revealed 53 intraductal papillary mucinous neoplasms (19 branch duct IPMNs, 15 mixed type IPMNs, and 19 main duct IPMNs), 14 serous and 13 mucinous cystic neoplasms, 3 solid pseudopapillary neoplasms, and 3 other lesions...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/25788760/the-impact-of-changed-strategies-for-patients-with-cholangiocarcinoma-in-this-millenium
#17
Per Lindnér, Magnus Rizell, Lo Hafström
Background. Cholangiocarcinoma is a cancer with a poor prognosis. In this millennium there are new diagnostic and therapeutic strategies for these patients. Aim. The aim of this study was to find if these changes influenced survival of individuals with proximal cholangiocarcinoma. Material. 627 individuals with a diagnosis of cholangiocarcinoma (not including distal common duct cancer) during the period from 2000 to 2011 were registered in Sweden's Western Region. The material was divided into three consecutive time periods...
2015: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/25548432/laparoscopic-versus-open-liver-resection-differences-in-intraoperative-and-early-postoperative-outcome-among-cirrhotic-patients-with-hepatocellular-carcinoma-a-retrospective-observational-study
#18
Antonio Siniscalchi, Giorgio Ercolani, Giulia Tarozzi, Lorenzo Gamberini, Lucia Cipolat, Antonio D Pinna, Stefano Faenza
Introduction. Laparoscopic liver resection is considered risky in cirrhotic patients, even if minor surgical trauma of laparoscopy could be useful to prevent deterioration of a compromised liver function. This study aimed to identify the differences in terms of perioperative complications and early outcome in cirrhotic patients undergoing minor hepatic resection for hepatocellular carcinoma with open or laparoscopic technique. Methods. In this retrospective study, 156 cirrhotic patients undergoing liver resection for hepatocellular carcinoma were divided into two groups according to type of surgical approach: laparoscopy (LS group: 23 patients) or laparotomy (LT group: 133 patients)...
2014: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/25505821/primary-leiomyoma-of-the-liver-a-review-of-a-rare-tumour
#19
REVIEW
Ayodeji Oluwarotimi Omiyale
Context. Primary leiomyoma of the liver is a rare tumour with uncertain pathogenesis with similar presentation with other tumours of the liver. Little is known about its clinical course. Objectives. To review the literature for case reports of primary leiomyoma of the liver. Methods. Extensive literature search was carried out for case reports of primary leiomyoma of the liver. Results. A total of 36 cases of primary leiomyoma of the liver were reviewed. The mean age of presentation is 43 years with slight female sex affectation; females accounted for 55...
2014: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
https://www.readbyqxmd.com/read/25505820/risk-factors-associated-with-reoperation-for-bleeding-following-liver-transplantation
#20
Maxwell A Thompson, David T Redden, Lindsey Glueckert, A Blair Smith, Jack H Crawford, Keith A Jones, Devin E Eckhoff, Stephen H Gray, Jared A White, Joseph Bloomer, Derek A DuBay
Introduction. This study's objective was to identify risk factors associated with reoperation for bleeding following liver transplantation (LTx). Methods. A retrospective study was performed at a single institution between 2001 and 2012. Operative reports were used to identify patients who underwent reoperation for bleeding within 2 weeks following LTx (operations for nonbleeding etiologies were excluded). Results. Reoperation for bleeding was observed in 101/928 (10.8%) of LTx patients. The following characteristics were associated with reoperation on multivariable analysis: recipient MELD score (OR 1...
2014: HPB Surgery: a World Journal of Hepatic, Pancreatic and Biliary Surgery
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