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Clinical Oncology: a Journal of the Royal College of Radiologists

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https://www.readbyqxmd.com/read/28811150/best-practice-recommendations-for-the-retention-of-radiotherapy-records
#1
E Lockhart, K Bak, L J Schreiner, D C Hodgson, E Gutierrez, P Warde, M B Sharpe
This paper offers best practice recommendations for the maintenance and retention of radiotherapy health records and technical information for cancer programmes. The recommendations are based on a review of the published and grey literature, feedback from key informants from seven countries and expert consensus. Ideally, complete health records should be retained for 5 years beyond the patient's lifetime, regardless of where they are created and maintained. Technical information constituting the radiotherapy plan should also be retained beyond the patient's lifetime for 5 years, including the primary images, contours of delineated targets and critical organs, dose distributions and other radiotherapy plan objects...
August 12, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28807361/challenges-to-treating-older-glioblastoma-patients-the-influence-of-clinical-and-tumour-characteristics-on-survival-outcomes
#2
C F Lorimer, C Hanna, F Saran, A Chalmers, J Brock
AIMS: There is now evidence to support giving single-agent chemotherapy, radiotherapy or hypofractionated concurrent chemoradiotherapy to older patients with glioblastoma (GBM). However, the clinical basis on which treatment decisions are made is under-researched and not standardised. This retrospective, multicentre study assessed whether pre-morbid characteristics or tumour imaging features could predict for overall survival in a cohort of older patients with GBM. MATERIALS AND METHODS: Patients aged > 70 years, diagnosed with GBM at three neuro-oncology centres from 2010 to 2015 were retrospectively analysed...
August 11, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28807360/introducing-the-cancer-research-uk-advanced-radiotherapy-technologies-network-art-net
#3
EDITORIAL
K Harrington, E Hall, M Hawkins, A Henry, R MacKay, T Maughan, A McDonald, C Nutting, U Oelfke, D Sebag-Montefiore, R A Sharma, M van Herk, C Faivre-Finn
No abstract text is available yet for this article.
August 11, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28803687/predictors-of-asymptomatic-radiation-induced-abdominal-atherosclerosis
#4
L Cella, R Liuzzi, P Romanelli, M Conson, V D'Avino, M Ottaviano, V Damiano, G Palmieri, R Pacelli, M Mancini
AIMS: To identify predictors of asymptomatic radiation-induced abdominal atherosclerosis in patients treated with radiotherapy and evaluated by abdominal vascular ultrasonography. MATERIALS AND METHODS: Forty-two testicular classic seminoma patients (median age 34 years, range 16-56) undergoing radical inguinal orchiectomy were analysed. Twenty-six patients underwent post-surgery radiotherapy (median total dose 25 Gy, range 25-43), two of them also received chemotherapy (CHT) and 16 patients were treated with surgery alone or by surgery followed by CHT (control group)...
August 10, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28803686/are-cyclin-dependent-kinase-4-6-inhibitors-needed-for-all-oestrogen-receptor-positive-metastatic-breast-cancers
#5
EDITORIAL
S R D Johnston
No abstract text is available yet for this article.
August 10, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28781199/data-mining-in-oncology-the-ukcat-project-and-the-practicalities-of-working-with-routine-patient-data
#6
EDITORIAL
G Price, M van Herk, C Faivre-Finn
No abstract text is available yet for this article.
August 3, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28780009/treatment-variation-of-sequential-versus-concurrent-chemoradiotherapy-in-stage-iii-non-small-cell-lung-cancer-patients-in-the-netherlands-and-belgium
#7
I Walraven, R A Damhuis, M G Ten Berge, M Rosskamp, L van Eycken, D de Ruysscher, J S A Belderbos
AIMS: Concurrent chemoradiotherapy (CCRT) is considered the standard treatment regimen in non-surgical locally advanced non-small cell lung cancer (NSCLC) patients and sequential chemoradiotherapy (SCRT) is recommended in patients who are unfit to receive CCRT or when the treatment volume is considered too large. In this study, we investigated the proportion of CCRT/SCRT in the Netherlands and Belgium. Furthermore, patient and disease characteristics associated with SCRT were assessed...
August 2, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28780008/the-role-of-positron-emission-tomography-computed-tomography-imaging-in-head-and-neck-cancer-after-radical-chemoradiotherapy-a-single-institution-experience
#8
C Nelissen, J Sherriff, T Jones, P Guest, S Colley, P Sanghera, A Hartley
AIMS: Positron emission tomography/computed tomography (PET/CT) is used to restage head and neck cancer 3 months after chemoradiotherapy. The purpose of this study was to determine the negative predictive value (NPV) of a scan reported as having no abnormal uptake and the positive predictive values (PPV) for different maximum standardised uptake value (SUVmax) thresholds. MATERIALS AND METHODS: Patients with squamous cell carcinoma of the oro-/hypopharynx/larynx (n = 206) were included...
August 2, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28739028/incident-learning-systems-for-radiation-oncology-development-and-value-at-the-local-national-and-international-level
#9
T Pawlicki, M Coffey, M Milosevic
AIMS: To discuss the background for incident reporting and learning systems, as well as the infrastructure and operational aspects to run them. MATERIALS AND METHODS: Information from peer-reviewed literature, online resources and the authors' experience synthesised into a concise understanding of the topic. RESULTS: Incident learning systems can be local, national or international, each having the same basic goals but facilitating different audiences and environments...
July 21, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28728883/long-term-survival-outcomes-of-primary-breast-cancer-in-women-with-or-without-preoperative-magnetic-resonance-imaging-a%C3%A2-matched-cohort-study
#10
W J Choi, J H Cha, H H Kim, H J Shin, E Y Chae, K H Jung, J-H Ahn, S-B Kim, B H Son, S H Ahn
AIMS: To investigate whether preoperative magnetic resonance imaging (MRI) in patients with primary breast cancer is predictive of disease-free (DFS) and overall survival and to determine the prognostic factors indicating survival. MATERIALS AND METHODS: This retrospective study was approved by the institutional review board and the requirement for informed consent was waived. From 2009 to 2010, 828 women with primary breast cancer and preoperative MRI were matched with 1613 women without such imaging...
July 17, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28712786/the-relationship-between-hot-flashes-and-testosterone-recovery-after-12-months-of-androgen-suppression-for-men-with-localised-prostate-cancer-in-the-ascende-rt-trial
#11
M Dosani, W J Morris, S Tyldesley, T Pickles
AIMS: This study describes the proportion of men who experienced hot flashes (flashes), and the testosterone level at onset, peak frequency and cessation of flashes after 12 months of androgen deprivation therapy (ADT) in men undergoing curative-intent external beam radiation therapy (± brachytherapy boost). We also aimed to characterise testosterone recovery in this population. MATERIALS AND METHODS: This was a pre-specified secondary analysis of the ASCENDE-RT clinical trial...
July 13, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28711307/medical-error-a-patient-s-perspective
#12
EDITORIAL
E D Naessens
No abstract text is available yet for this article.
July 13, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28711306/can-the-aviation-industry-be-useful-in-teaching-oncology-about-safety
#13
J M Davies, G Delaney
Healthcare practitioners have long considered aviation as a domain from which much can be learned about safety. Over the past 30 years, attempts have been made to apply aviation safety-related concepts to healthcare. Although some applications have been successful, a few decades later, many healthcare safety experts have learned that the appeal of the aviation-healthcare analogy is an illusion. Both domains are so basically dissimilar that simple adoption of aviation concepts will not be successful. However, what has succeeded is healthcare's adaptation of specific aviation safety concepts...
July 12, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28693823/feasibility-of-hippocampal-avoidance-radiotherapy-for-glioblastoma
#14
K Thippu Jayaprakash, K Wildschut, R Jena
With improvements in survival for good performance status patients and in specific molecular subtypes of glioblastoma, some patients will survive to develop significant neurocognitive dysfunction. This retrospective planning study quantified hippocampal radiation doses in patients with glioblastoma receiving radical chemo-radiotherapy and compared this with the radiation doses that showed clinical correlation with neurocognitive dysfunction, and evaluated the potential for clinically meaningful hippocampal dose reduction using helical TomoTherapy(®)...
July 7, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28687408/development-of-postoperative-radiotherapy-for-breast-cancer-uk-consensus-statements-a-model-of-patient-clinical-and-commissioner-engagement
#15
EDITORIAL
D J Bloomfield
No abstract text is available yet for this article.
July 4, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28669449/neoadjuvant-therapy-in-early-breast-cancer-treatment-considerations-and-common-debates-in-practice
#16
H Cain, I R Macpherson, M Beresford, S E Pinder, J Pong, J M Dixon
Neoadjuvant treatment offers a number of benefits for patients with early breast cancer, and is an important option for consideration by multidisciplinary teams. Despite literature showing its efficacy, the use of neoadjuvant therapy varies widely. Here we discuss the clinical evidence supporting the use of neoadjuvant therapy in early stage breast cancer, including patient selection, monitoring response, surgery and radiotherapy considerations, with the aim of assisting multidisciplinary teams to determine patient suitability for neoadjuvant treatment...
June 29, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28666763/is-the-current-american-society-of-clinical-oncology-guidance-on-axillary-management-generalisable-for-symptomatic-or-unscreened-breast-cancers
#17
LETTER
S Chatterjee, S Agrawal, C Nallathambi, R Ahmed
No abstract text is available yet for this article.
June 28, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28662794/lessons-learnt-from-past-incidents-and-accidents-in-radiation-oncology
#18
T Knöös
The purpose of this report is to review and compile what have been and can be learnt from incidents and accidents in radiation oncology, especially in external beam and brachytherapy. Some major accidents from the last 20 years will be discussed. The relationship between major events and minor or so-called near misses is mentioned, leading to the next topic of exploring the knowledge hidden among them. The main lessons learnt from the discussion here and elsewhere are that a well-functioning and safe radiotherapy department should help staff to work with awareness and alertness and that documentation and procedures should be in place and known by everyone...
June 26, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28652093/prediction-of-90-day-and-overall-survival-after-chemoradiotherapy-for-lung-cancer-role-of-performance-status-and-body-composition
#19
J C S Bowden, L J Williams, A Simms, A Price, S Campbell, M T Fallon, K C H Fearon
AIMS: If appropriate patients are to be selected for lung cancer treatment, an understanding of who is most at risk of adverse outcomes after treatment is needed. The aim of the present study was to identify predictive factors for 30 and 90 day mortality after chemoradiotherapy (CRT), and factors that were prognostic for overall survival. MATERIALS AND METHODS: A retrospective cohort study of 194 patients with lung cancer who had undergone CRT in South East Scotland from 2008 to 2010 was undertaken...
June 23, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28652092/upfront-docetaxel-in-the-post-stampede-world-lessons-from-an-early-evaluation-of-non-trial-usage-in-hormone-sensitive-prostate-cancer
#20
LETTER
A Patrikidou, M Uccello, A Tree, C Parker, G Attard, R Eeles, V Khoo, N van As, R Huddart, D Dearnaley, A Reid
No abstract text is available yet for this article.
June 23, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
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