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Clinical Oncology: a Journal of the Royal College of Radiologists

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https://www.readbyqxmd.com/read/29773446/effects-of-preparatory-coaching-and-home-practice-for-deep-inspiration-breath-hold-on-cardiac-dose-for-left-breast-radiation-therapy
#1
A Kim, A M Kalet, N Cao, D S Hippe, L C Fang, L Young, J Meyer, E V Lang, N A Mayr
AIMS: Deep inspiration breath hold (DIBH) reduces cardiac radiation exposure by creating cardiac-chest wall separation in breast cancer radiotherapy. DIBH requires sustaining chest wall expansion for up to 40 s and involves complex co-ordination of thoraco-abdominal muscles, which may not be intuitive to patients. We investigated the effect of in-advance preparatory DIBH coaching and home practice on cardiac doses. MATERIALS AND METHODS: Successive patients from 1 February 2015 to 31 December 2016 with left-sided breast cancer who underwent tangential field radiotherapy utilising the DIBH technique were included...
May 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29753663/medicine-s-achilles-heel-errors-and-variations
#2
LETTER
Shing Fung Lee
No abstract text is available yet for this article.
May 9, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29753662/clinical-value-of-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-response-evaluation-after-primary-treatment-of-advanced-epithelial-ovarian-cancer
#3
J Hynninen, M Laasik, T Vallius, J Kemppainen, S Grönroos, J Virtanen, J Casado, S Hautaniemi, S Grenman, M Seppänen, A Auranen
AIMS: To prospectively evaluate the use of 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (18 F-FDG-PET/CT) in the definition of the treatment response after primary treatment of advanced epithelial ovarian cancer (EOC). MATERIALS AND METHODS: Forty-nine patients with advanced EOC had an 18 F-FDG PET/CT scan before and after primary treatment. The treatment response was defined with the currently used radiological and serological Response Criteria in Solid Tumors (RECIST1...
May 9, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29743148/when-should-surgery-be-used-for-recurrent-ovarian-carcinoma
#4
M Bommert, P Harter, F Heitz, A du Bois
Cytoreductive surgery is an important column in the treatment of primary ovarian cancer. Surgical outcome is one of the most important prognostic factors and one of the few prognostic variables that can be influenced by therapists. Retrospective studies suggested that only complete cytoreduction was associated with a benefit. Therefore, definition of predictors of complete resection is of the utmost importance to avoid surgical burden in patients with both limited benefit of the procedure and limited overall life expectancy...
May 7, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29735311/inadequate-rates-of-brca-testing-with-its-negative-consequences-for-women-with-epithelial-ovarian-cancer-and-their-families-an-overview-of-the-literature
#5
P J Hoskins
Fifteen per cent of women with epithelial ovarian cancer possess inherited mutations in the BRCA genes. Knowledge of her BRCA status is important to her and her family. Poly(ADP-ribose) polymerase (PARP) inhibitors provide a new therapeutic option for her. For her family it provides the opportunity for the prevention of what otherwise is often a lethal disease. To access these opportunities, the mandatory first step is testing the woman with the cancer. However, referral rates for genetic counselling and subsequent BRCA testing are low, in the of 10-30% range...
May 5, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29731385/image-guided-adaptive-brachytherapy-for-cervix-cancer-a-story-of-successful-collaboration-within-the-gec-estro-gyn-network-and-the-embrace-studies
#6
EDITORIAL
L T Tan, K Tanderup, P Hoskin, R Cooper, R Pötter
No abstract text is available yet for this article.
May 3, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29716767/radiobiology-of-acute-rectal-toxicity
#7
LETTER
B J Masters, A Pascoe, G Walker, S Sundar
No abstract text is available yet for this article.
April 28, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29709254/systematic-outcome-documentation-and-potential-impact-of-new-international-delineation-guidelines-for-head-and-neck-contouring-peer-review
#8
LETTER
C Fong, J Good, M Hickman, A Hartley, P Sanghera
No abstract text is available yet for this article.
April 27, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29706398/whole-brain-radiotherapy-in-metastatic-non-small-cell-lung-cancer-the-debate-should-continue
#9
LETTER
L Solway, Q Ghafoor, R Stevenson, S Watkins, S Yahya
No abstract text is available yet for this article.
April 26, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29691126/outcome-and-prognostic-impact-of-surgical-staging-in-serous-tubal-intraepithelial-carcinoma-a-cohort-study-and-systematic-review
#10
N M A Van der Hoeven, K Van Wijk, S E Bonfrer, J J Beltman, L A Louwe, C D De Kroon, C J Van Asperen, K N Gaarenstroom
The optimal management of breast cancer susceptibility gene (BRCA)1/2 carriers with isolated serous tubal intraepithelial carcinoma (STIC) found at risk-reducing salpingo-oophorectomy (RRSO) is unclear. The prevalence of occult carcinoma and STIC in a consecutive series of BRCA1/2 carriers undergoing RRSO is reported. The outcome of staging procedures in BRCA1/2 carriers with isolated STIC at RRSO as well as the relationship between staging, chemotherapy treatment and risk of recurrence was assessed via a systematic review of the literature...
April 21, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29680734/hospital-choice-in-cancer-care-a-qualitative-study
#11
A Aggarwal, S Bernays, H Payne, J van der Meulen, C Davis
AIMS: There is limited evidence about how patients respond to hospital choice policies, the factors that inform and influence patient choices or how relevant these policies are to cancer patients. This study sought to evaluate hospital choice policies from the perspective of men who received treatment for prostate cancer in the English National Health Service. MATERIALS AND METHODS: Semi-structured interviews were undertaken with a purposive sample of 25 men across England...
April 19, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29680735/glioma-re-irradiation-and-neurocognitive-dysfunction
#12
LETTER
A L K Ho, R Jena
No abstract text is available yet for this article.
April 18, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29655554/uk-consensus-on-normal-tissue-dose-constraints-for-stereotactic-radiotherapy-reply-to-ghafoor-et-al
#13
LETTER
G G Hanna, F McDonald, L Murray, S Harrow, D Landau, M Ahmed, K N Franks
No abstract text is available yet for this article.
April 11, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29653749/women-s-free-text-comments-on-their-quality-of-life-an-exploratory-analysis-from-the-uk-standardisation-of-breast-radiotherapy-start-trials-for-early-breast-cancer
#14
J Mills, J S Haviland, C Moynihan, J M Bliss, P Hopwood
AIMS: Exploratory analysis of patients' unsolicited written comments in the first 2 years of the Standardisation of Breast Radiotherapy (START) trial quality of life study highlighted a potential effect of non-treatment-related problems on the ratings and interpretation of patient self-reported questionnaires. At 5 years of follow-up all eligible subjects were invited to write comments to further explore these findings. MATERIALS AND METHODS: Using inductive qualitative methods informed by the exploratory analysis, comments were allocated to relevant themes...
April 10, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29653748/cervical-spine-fractures-in-patients-undergoing-palliative-radiotherapy-to-the-cervical-spine-implications-for-practice
#15
LETTER
C Shelley, M Gore, S Tan, K Thomas, R Eeles
No abstract text is available yet for this article.
April 10, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29627271/biology-is-the-king
#16
LETTER
B D Yıldız, B Saylam, S Er, M Tez
No abstract text is available yet for this article.
April 4, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29627270/re-irradiation-of-the-brain
#17
LETTER
P Windsor
No abstract text is available yet for this article.
April 4, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29615284/external-beam-radiotherapy-in-the-treatment-of-gastroenteropancreatic-neuroendocrine-tumours-a-systematic-review
#18
D L Chan, R Thompson, M Lam, N Pavlakis, J Hallet, C Law, S Singh, S Myrehaug
AIMS: External beam radiotherapy (EBRT) is infrequently used to treat gastroenteropancreatic neuroendocrine tumours (GEPNETS), with little published data to date. We carried out a systematic review to assess the activity of EBRT for GEPNETS. MATERIALS AND METHODS: Major databases were searched for papers including at least five patients treated with contemporary EBRT techniques. Eligible studies underwent dual independent review. The primary end points were response rate for lesions treated with definitive intent and recurrence-free survival for primary lesions treated with neoadjuvant or adjuvant intent...
March 31, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29602584/stomach-dose-volume-predicts-acute-gastrointestinal-toxicity-in-chemoradiotherapy-for-locally-advanced-pancreatic-cancer
#19
D L P Holyoake, D R Warren, C Hurt, M Aznar, M Partridge, S Mukherjee, M A Hawkins
AIMS: Gastrointestinal toxicity impedes dose escalation in chemoradiotherapy for hepatobiliary malignancies. Toxicity risk depends on clinical and radiotherapy metrics. We aimed to identify predictive factors using data from two prospective phase II clinical trials of locally advanced pancreatic cancer (LAPC). MATERIALS AND METHODS: Ninety-one patients with available data from the ARCII (59.4 Gy in 33 fractions with gemcitabine, cisplatin and nelfinavir, n = 23) and SCALOP (50...
March 27, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29580696/outcomes-in-patients-treated-with-post-mastectomy-chest-wall-radiotherapy-without-the-routine-use-of-bolus
#20
M L Yap, M Tieu, J Sappiatzer, T Panzarella, J Cuartero, D McCready, A Fyles
AIMS: The use of bolus in post-mastectomy radiotherapy (PMRT) varies significantly between institutions. We report on chest wall recurrence and acute toxicity rates for PMRT patients treated with selective use of bolus. MATERIALS AND METHODS: We analysed PMRT patients who received adjuvant chest wall radiotherapy for invasive breast cancer between 2004 and 2009. Patient, tumour and cancer outcomes were collected from a prospective database, with additional radiotherapy and acute toxicity details supplemented retrospectively...
March 23, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
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