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Clinical Oncology: a Journal of the Royal College of Radiologists

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https://www.readbyqxmd.com/read/28712786/the-relationship-between-hot-flashes-and-testosterone-recovery-after-12-months-of-androgen-suppression-for-men-with-localised-prostate-cancer-in-the-ascende-rt-trial
#1
M Dosani, W J Morris, S Tyldesley, T Pickles
AIMS: This study describes the proportion of men who experienced hot flashes (flashes), and the testosterone level at onset, peak frequency and cessation of flashes after 12 months of androgen deprivation therapy (ADT) in men undergoing curative-intent external beam radiation therapy (± brachytherapy boost). We also aimed to characterise testosterone recovery in this population. MATERIALS AND METHODS: This was a pre-specified secondary analysis of the ASCENDE-RT clinical trial...
July 13, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28711307/medical-error-a-patient-s-perspective
#2
EDITORIAL
E D Naessens
No abstract text is available yet for this article.
July 13, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28711306/can-the-aviation-industry-be-useful-in-teaching-oncology-about-safety
#3
J M Davies, G Delaney
Healthcare practitioners have long considered aviation as a domain from which much can be learned about safety. Over the past 30 years, attempts have been made to apply aviation safety-related concepts to healthcare. Although some applications have been successful, a few decades later, many healthcare safety experts have learned that the appeal of the aviation-healthcare analogy is an illusion. Both domains are so basically dissimilar that simple adoption of aviation concepts will not be successful. However, what has succeeded is healthcare's adaptation of specific aviation safety concepts...
July 12, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28693823/feasibility-of-hippocampal-avoidance-radiotherapy-for-glioblastoma
#4
K Thippu Jayaprakash, K Wildschut, R Jena
With improvements in survival for good performance status patients and in specific molecular subtypes of glioblastoma, some patients will survive to develop significant neurocognitive dysfunction. This retrospective planning study quantified hippocampal radiation doses in patients with glioblastoma receiving radical chemo-radiotherapy and compared this with the radiation doses that showed clinical correlation with neurocognitive dysfunction, and evaluated the potential for clinically meaningful hippocampal dose reduction using helical TomoTherapy(®)...
July 7, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28687408/development-of-postoperative-radiotherapy-for-breast-cancer-uk-consensus-statements-a-model-of-patient-clinical-and-commissioner-engagement
#5
EDITORIAL
D J Bloomfield
No abstract text is available yet for this article.
July 4, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28669449/neoadjuvant-therapy-in-early-breast-cancer-treatment-considerations-and-common-debates-in-practice
#6
H Cain, I R Macpherson, M Beresford, S E Pinder, J Pong, J M Dixon
Neoadjuvant treatment offers a number of benefits for patients with early breast cancer, and is an important option for consideration by multidisciplinary teams. Despite literature showing its efficacy, the use of neoadjuvant therapy varies widely. Here we discuss the clinical evidence supporting the use of neoadjuvant therapy in early stage breast cancer, including patient selection, monitoring response, surgery and radiotherapy considerations, with the aim of assisting multidisciplinary teams to determine patient suitability for neoadjuvant treatment...
June 29, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28666763/is-the-current-american-society-of-clinical-oncology-guidance-on-axillary-management-generalisable-for-symptomatic-or-unscreened-breast-cancers
#7
LETTER
S Chatterjee, S Agrawal, C Nallathambi, R Ahmed
No abstract text is available yet for this article.
June 28, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28662793/medical-error-the-perspective-of-the-clinician-and-the-director-of-a-department-involved-in-an-error
#8
EDITORIAL
G P Delaney, G Papadatos
No abstract text is available yet for this article.
June 27, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28662794/lessons-learnt-from-past-incidents-and-accidents-in-radiation-oncology
#9
T Knöös
The purpose of this report is to review and compile what have been and can be learnt from incidents and accidents in radiation oncology, especially in external beam and brachytherapy. Some major accidents from the last 20 years will be discussed. The relationship between major events and minor or so-called near misses is mentioned, leading to the next topic of exploring the knowledge hidden among them. The main lessons learnt from the discussion here and elsewhere are that a well-functioning and safe radiotherapy department should help staff to work with awareness and alertness and that documentation and procedures should be in place and known by everyone...
June 26, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28652093/prediction-of-90-day-and-overall-survival-after-chemoradiotherapy-for-lung-cancer-role-of-performance-status-and-body-composition
#10
J C S Bowden, L J Williams, A Simms, A Price, S Campbell, M T Fallon, K C H Fearon
AIMS: If appropriate patients are to be selected for lung cancer treatment, an understanding of who is most at risk of adverse outcomes after treatment is needed. The aim of the present study was to identify predictive factors for 30 and 90 day mortality after chemoradiotherapy (CRT), and factors that were prognostic for overall survival. MATERIALS AND METHODS: A retrospective cohort study of 194 patients with lung cancer who had undergone CRT in South East Scotland from 2008 to 2010 was undertaken...
June 23, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28652092/upfront-docetaxel-in-the-post-stampede-world-lessons-from-an-early-evaluation-of-non-trial-usage-in-hormone-sensitive-prostate-cancer
#11
LETTER
A Patrikidou, M Uccello, A Tree, C Parker, G Attard, R Eeles, V Khoo, N van As, R Huddart, D Dearnaley, A Reid
No abstract text is available yet for this article.
June 23, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28648744/safety-in-radiotherapy-mini-series
#12
EDITORIAL
G P Delaney
No abstract text is available yet for this article.
June 22, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28647432/peer-assisted-learning-intensity-modulated-radiotherapy-transition-in-developing-countries
#13
I Mohamad, A Salem, T Abu Hejleh, S Wadi-Ramahi, M Qandeel, S El Khatib, W Asha, S Mhied, O Al Saraireh, W Al-Gargaz, H Abdulelah, A Hosni, A Al Mousa
Intensity-modulated radiotherapy (IMRT) is not widely used in developing countries due to technical challenges and a lack of expertise and resources. We outline head and neck cancer IMRT implementation challenges and highlight how improvised solutions allowed successful IMRT transition in Jordan. This article showcases a 'peer-assisted learning' model, promoting IMRT transition in other developing countries. Unlike the 'top-down' approach, this model is uncommonly addressed in oncology journals. Developing countries could benefit from this article to enhance the adoption of modern radiotherapy technology...
June 21, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28633969/single-fraction-radiotherapy-should-be-the-standard-of-care-for-palliation-of-cancer-symptoms-in-patients-with-limited-life-expectancy
#14
LETTER
J M Price, T Wolfe, E Shawcroft, S Sundar
No abstract text is available yet for this article.
June 17, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28610760/iatrogenic-kaposi-s-sarcoma-a-retrospective-cohort-study-in-an-italian-tertiary-care-centre
#15
L Brambilla, A Tourlaki, G Genovese
AIMS: Kaposi's sarcoma (KS) is a lymphoangioproliferative multicentric disorder. Among its four distinct clinical variants, iatrogenic KS (iKS) typically affects patients who have received immunosuppressant regimens for organ transplants, proliferative disorders, or immune-mediated diseases. The aim of the current study was to examine the characteristics of a cohort of patients with iKS, evaluating the differences in terms of epidemiological and clinical features, management and outcomes between organ transplant recipients (OTR) and patients immunosuppressed for other medical conditions...
June 10, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28602357/postgraduate-training-in-a-low-and-middle-income-country-sharing%C3%A2-experience-from-a-joint-commission-international-accreditation-accredited-university-hospital
#16
LETTER
M U Karim, A Nadeem Abbasi, N Ali, A Hafiz, B M Qureshi, B Mir
No abstract text is available yet for this article.
June 8, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28595873/borderline-sarcomas-and-smooth-muscle-tumours-of-uncertain-malignant-potential
#17
S Prewett, G Horan, H Hatcher, T Ajithkumar
Borderline sarcomas and smooth muscle tumours of uncertain malignant potential (STUMP) have an unpredictable clinical behaviour with frequent local recurrences and rarely, metastases. We review the current management of common subtypes of borderline sarcomas and STUMP.
June 5, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28592379/comprehensive-geriatric-assessment-in-men-aged-70-years-or-older-with-localised-prostate-cancer-undergoing-radical-radiotherapy
#18
G E C Osborne, S A Appleyard, D C Gilbert, C I Jones, C Lorimer, M Villanueva, E Peasgood, A Robinson, A Nikapota, A Ring
AIMS: Treatment decisions for men aged 70 years or over with localised prostate cancer need to take into account the risk of death from competing causes and fitness for the proposed treatment. Objective assessments such as those included in a comprehensive geriatric assessment (CGA) might help to inform the decision-making process. The aim of this study was to describe the CGA scores of a cohort of older men with prostate cancer, evaluate potential screening tools in this population and assess whether any CGA component predicts significant acute radiotherapy toxicity...
June 4, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28583345/multidisciplinary-management-of-sarcomas-where-are-we-now
#19
EDITORIAL
T V Ajithkumar, H Hatcher
No abstract text is available yet for this article.
June 2, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28552518/systemic-treatments-in-soft-tissue-sarcomas
#20
H Hatcher, C Benson, T Ajithkumar
Systematic treatment of adult-type soft tissue sarcoma is evolving. Its role in the neoadjuvant setting is currently experimental, whereas the data on adjuvant chemotherapy are inconclusive. Nevertheless, in clinical practice, neoadjuvant and adjuvant chemotherapy may be considered on an individual basis after multidisciplinary discussion. Systemic therapy has a well-established role in the management of locally advanced and metastatic disease and histology-based treatment approaches are being studied.
May 26, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
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