journal
MENU ▼
Read by QxMD icon Read
search

Clinical Oncology: a Journal of the Royal College of Radiologists

journal
https://www.readbyqxmd.com/read/27916340/the-benefits-of-providing-external-beam-radiotherapy-in-low-and-middle-income-countries
#1
M L Yap, T P Hanna, J Shafiq, J Ferlay, F Bray, G P Delaney, M Barton
More than half of all cancer diagnoses worldwide occur in low- and middle-income countries (LMICs) and the incidence is projected to rise substantially within the next 20 years. Radiotherapy is a vital, cost-effective treatment for cancer; yet there is currently a huge deficit in radiotherapy services within these countries. The aim of this study was to estimate the potential outcome benefits if external beam radiotherapy was provided to all patients requiring such treatment in LMICs, according to the current evidence-based guidelines...
December 1, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27914679/postgraduate-education-in-radiation-oncology-in-low-and-middle-income-countries
#2
J G Eriksen
Radiation therapy is one of the most cost-effective ways to treat cancer patients on both a curative and palliative basis in low- and middle-income countries (LMICs). Despite this, the gap in radiation oncology capacity is enormous and is even increasing due to a rapid rise in the incidence of cancer cases in LMICs. The urgent need for radiotherapy resources in terms of bunkers and megavoltage machines is important, but equally important is the tremendous lack of properly educated health care professionals...
November 30, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27913106/innovations-in-radiotherapy-technology
#3
I J Feain, L Court, J R Palta, S Beddar, P Keall
Many low- and middle-income countries, together with remote and low socioeconomic populations within high-income countries, lack the resources and services to deal with cancer. The challenges in upgrading or introducing the necessary services are enormous, from screening and diagnosis to radiotherapy planning/treatment and quality assurance. There are severe shortages not only in equipment, but also in the capacity to train, recruit and retain staff as well as in their ongoing professional development via effective international peer-review and collaboration...
November 29, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27908503/cobalt-60-machines-and-medical-linear-accelerators-competing-technologies-for-external-beam-radiotherapy
#4
B J Healy, D van der Merwe, K E Christaki, A Meghzifene
Medical linear accelerators (linacs) and cobalt-60 machines are both mature technologies for external beam radiotherapy. A comparison is made between these two technologies in terms of infrastructure and maintenance, dosimetry, shielding requirements, staffing, costs, security, patient throughput and clinical use. Infrastructure and maintenance are more demanding for linacs due to the complex electric componentry. In dosimetry, a higher beam energy, modulated dose rate and smaller focal spot size mean that it is easier to create an optimised treatment with a linac for conformal dose coverage of the tumour while sparing healthy organs at risk...
November 28, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27894673/treatment-related-death-in-cancer-patients-treated-with-immune-checkpoint-inhibitors-a-systematic-review-and-meta-analysis
#5
O Abdel-Rahman, D Helbling, J Schmidt, U Petrausch, A Giryes, A Mehrabi, O Schöb, M Mannhart, H Oweira
AIMS: We carried out a meta-analysis to determine the risk of treatment-related death associated with immune checkpoint inhibitor use in cancer patients. MATERIALS AND METHODS: We examined data from the Medline and Google Scholar databases. We also examined original studies and review articles for cross-references. Eligible studies included randomised phase II and phase III trials of patients with cancer treated with ipilimumab, pembrolizumab; nivolumab; tremelimumab and atezolizumab...
November 25, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27890346/the-uk-heartspare-study-stage-ii-multicentre-evaluation-of-a-voluntary-breath-hold-technique-in-patients-receiving-breast-radiotherapy
#6
F R Bartlett, E M Donovan, H A McNair, L A Corsini, R M Colgan, P M Evans, L Maynard, C Griffin, J S Haviland, J R Yarnold, A M Kirby
AIMS: To evaluate the feasibility and heart-sparing ability of the voluntary breath-hold (VBH) technique in a multicentre setting. MATERIALS AND METHODS: Patients were recruited from 10 UK centres. Following surgery for early left breast cancer, patients with any heart inside the 50% isodose from a standard free-breathing tangential field treatment plan underwent a second planning computed tomography (CT) scan using the VBH technique. A separate treatment plan was prepared on the VBH CT scan and used for treatment...
November 24, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27847135/medical-physics-challenges-for-the-implementation-of-quality-assurance-programmes-in-radiation-oncology
#7
A Meghzifene
The importance of quality assurance in radiation therapy, as well as its positive consequences on patient treatment outcome, is well known to radiation therapy professionals. In low- and middle-income countries, the implementation of quality assurance in radiation therapy is especially challenging, due to a lack of staff training, a lack of national guidelines, a lack of quality assurance equipment and high patient daily throughput. According to the International Atomic Energy Agency (IAEA) Directory of Radiotherapy Centres, the proportion of linear accelerators compared with Co-60 machines has increased significantly in recent years in low- and middle-income countries...
November 12, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27839942/training-in-clinical-oncology-and-the-transition-from-trainee-to-consultant-results-of-the-royal-college-of-radiologists-2015-post-certificate-of-completion-of-training-survey
#8
J Dickson, D Liu, D Bloomfield
AIMS: To seek feedback from clinical oncologists as to their experiences of specialty training and, where applicable, the transition to working as a consultant in the National Health Service. MATERIALS AND METHODS: All clinical oncologists gaining a Certificate of Completion of Training between 1 July 2012 and 30 June 2014 were identified through records held by the Royal College of Radiologists and approached in May 2015 to take part in an online survey. RESULTS: The survey was completed by 38 of 80 clinical oncologists invited to take part (48% response rate)...
November 10, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27838135/the-impact-of-systemic-therapy-beyond-first-line-treatment-for-advanced-cervical-cancer
#9
J McLachlan, S Boussios, A Okines, D Glaessgen, S Bodlar, R Kalaitzaki, A Taylor, S Lalondrelle, M Gore, S Kaye, S Banerjee
AIMS: Despite recent advances in the primary and secondary prevention of cervical cancer, a significant number of women present with or develop metastatic disease. There is currently no consensus on the standard of care for second-line systemic treatment of recurrent/metastatic cervical cancer. The purpose of this study was to evaluate the second-line systemic therapy used and the associated outcomes in a single cancer centre. MATERIALS AND METHODS: A retrospective review of patients with cervical cancer who received one or more lines of treatment for recurrent or metastatic cervical cancer at the Royal Marsden Hospital between 2004 and 2014 was carried out...
November 9, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27829531/patterns-of-referral-to-radiation-oncology-among-patients-with-bladder-cancer-a-population-based-study
#10
J S Quirt, D R Siemens, K Zaza, W J Mackillop, C M Booth
AIMS: Radical radiotherapy is a reasonable alternative to cystectomy for some patients with invasive bladder cancer, and postoperative radiotherapy may be indicated in patients at high risk of local recurrence. Here we describe pre- and postoperative radiation oncology consultation among patients with bladder cancer in Ontario. MATERIALS AND METHODS: Records of radiotherapy and surgery were linked to the Ontario Cancer Registry (OCR) to identify all patients who received treatment with curative intent for bladder cancer between 1994 and 2008...
November 6, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27815039/standardisation-of-target-volume-delineation-for-carotid-sparing-intensity-modulated-radiotherapy-in-early-glottis-cancer
#11
D M Gujral, M Long, J W G Roe, K J Harrington, C M Nutting
AIMS: Recently, carotid-sparing intensity-modulated radiotherapy (IMRT) for early laryngeal glottis (T1/T2N0M0) cancer has generated interest in the hope of avoiding long-term carotid toxicity, as well as concerns relating to geographical misses and long-term normal tissue toxicity. The aim of this review was to summarise the current literature on carotid-sparing IMRT for early glottis cancer, with particular focus on definitions of target volumes and the carotid arteries as organs at risk...
November 1, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27810119/initial-results-from-the-royal-college-of-radiologists-uk-national-audit-of-anal-cancer-radiotherapy-2015
#12
R Muirhead, K Drinkwater, S M O'Cathail, R Adams, R Glynne-Jones, M Harrison, M A Hawkins, D Sebag-Montefiore, D C Gilbert
AIMS: UK guidance was recently developed for the treatment of anal cancer using intensity-modulated radiotherapy (IMRT). We audited the current use of radiotherapy in UK cancer centres for the treatment of anal cancer against such guidance. We describe the acute toxicity of IMRT in comparison with patient population in the audit treated with two-phase conformal radiotherapy and the previous published data from two-phase conformal radiotherapy, in the UK ACT2 trial. MATERIALS AND METHODS: A Royal College of Radiologists' prospective national audit of patients treated with radiotherapy in UK cancer centres was carried out over a 6 month period between February and July 2015...
October 31, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27789128/should-we-perform-genetic-testing-on-men-with-metastatic-prostate-cancer
#13
LETTER
C Mikropoulos
No abstract text is available yet for this article.
October 25, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27780695/real-time-image-guided-adaptive-predictive-prostate-radiotherapy-using-rectal-diameter-as-a-predictor-of-motion
#14
R Oates, A Brown, A Tan, F Foroudi, M Lim Joon, M Schneider, A Herschtal, T Kron
AIMS: To investigate a relationship between maximum rectal diameter (MRD) on pre-treatment cone beam computed tomography (CBCT) and intra-fraction prostate motion, in the context of an adaptive image-guided radiotherapy (IGRT) method. MATERIALS AND METHODS: The MRD was measured on 2125 CBCTs from 55 retrospective patient datasets and related to prostate displacement from intra-fraction imaging. A linear regression model was developed to determine a threshold MRD associated with a high probability of small prostate displacement...
October 22, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27780694/stereotactic-ablative-radiotherapy-versus-low-dose-rate-brachytherapy-or-external-beam-radiotherapy-propensity-score-matched-analyses-of-canadian-data
#15
A Loblaw, T Pickles, J Crook, A-G Martin, E Vigneault, L Souhami, F Cury, J Morris, C Catton, H Lukka, P Cheung, P Sethukavalan, A Warner, Y Yang, G Rodrigues
AIMS: To compare biochemical failure-free survival (BFFS) and overall survival for prostate cancer treated with stereotactic ablative radiotherapy (SABR), low dose rate (LDR) brachytherapy or external beam radiotherapy (EBRT) using a large Canadian multi-institutional database. MATERIALS AND METHODS: Patients with low risk localised prostate cancer treated with SABR, LDR or EBRT and no androgen deprivation therapy were selected. Propensity score matching was used to create two sets of matched cohorts with LDR and EBRT serving as control groups...
October 22, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27780693/validation-of-a-magnetic-resonance-imaging-based-auto-contouring-software-tool-for-gross-tumour-delineation-in-head-and-neck-cancer-radiotherapy-planning
#16
T Doshi, C Wilson, C Paterson, C Lamb, A James, K MacKenzie, J Soraghan, L Petropoulakis, G Di Caterina, D Grose
AIMS: To carry out statistical validation of a newly developed magnetic resonance imaging (MRI) auto-contouring software tool for gross tumour volume (GTV) delineation in head and neck tumours to assist in radiotherapy planning. MATERIALS AND METHODS: Axial MRI baseline scans were obtained for 10 oropharyngeal and laryngeal cancer patients. GTV was present on 102 axial slices and auto-contoured using the modified fuzzy c-means clustering integrated with the level set method (FCLSM)...
October 22, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27777147/hypofractionation-for-prostate-cancer-time-to-change
#17
D Dearnaley, I Syndikus, S Gulliford, E Hall
No abstract text is available yet for this article.
October 22, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27777146/the-rapid-access-palliative-ambulatory-radiotherapy-clinic-as-an-educational-tool-experience-of-leeds-cancer-centre
#18
F Slevin, S Namini, L Owen, E Dugdale, C Fosker, S Ramasamy, R Turner, C Coyle, G Radhakrishna
No abstract text is available yet for this article.
October 21, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27777145/characterisation-of-lesions-after-stereotactic-radiosurgery-for-brain-metastases-impact-of-delayed-contrast-magnetic-resonance-imaging
#19
S Wagner, H Gufler, G Eichner, H Lanfermann
AIMS: To investigate if brain metastases and radiation injuries after stereotactic radiosurgery (SRS) have different signal intensity (SI) time courses up to 55 min after contrast agent application and if delayed contrast magnetic resonance imaging (MRI) contributes to improve diagnostic accuracy. MATERIALS AND METHODS: Thirty-four consecutive patients treated with SRS for cerebral metastases were prospectively enrolled in the study. T1-weighted images were acquired on a 3-Tesla MR unit at three time points, at 2 (TP1), 15 (TP2) and 55 (TP3) min after administering contrast agent...
October 21, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27746041/breaking-the-glass-ceiling-for-women-in-academic-clinical-oncology-in-the-uk-a-personal-view
#20
C Faivre-Finn
No abstract text is available yet for this article.
October 14, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
journal
journal
30372
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"