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Clinical Oncology: a Journal of the Royal College of Radiologists

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https://www.readbyqxmd.com/read/30241798/postgraduate-global-health-competency-profile-for-radiation-oncology
#1
A Oar, M L Yap, D Rodin, A McNiven, J Papadakos, M Giuliani
AIMS: To identify core competencies for postgraduate radiation oncology trainees in global health and cancer that may inform revisions across radiation oncology residency specialty training curricula. MATERIALS AND METHODS: A review of the literature was conducted to identify all potential global health competency items. An international two-phase Delphi process was conducted with experts in oncology. In phase 1, all experts scored, on a nine-point Likert scale, the degree to which they agreed an item should be included in the competency profile...
September 18, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30236641/the-import-low-trial-collaborative-research-accelerates-practice-change-in-breast-radiotherapy
#2
EDITORIAL
A M Kirby, I S Bhattacharya, M Wilcox, J S Haviland
No abstract text is available yet for this article.
September 17, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30224204/the-road-map-for-proton-therapy-reply-to-professor-karol-sikora
#3
LETTER
A Crellin
No abstract text is available yet for this article.
September 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30224203/delivering-functional-imaging-on-the-mri-linac-current-challenges-and-potential-solutions
#4
A Datta, M C Aznar, M Dubec, G J M Parker, J P B O'Connor
Magnetic resonance imaging (MRI) is a highly versatile imaging modality that can be used to measure features of the tumour microenvironment including cell death, proliferation, metabolism, angiogenesis, and hypoxia. Mapping and quantifying these pathophysiological features has the potential to alter the use of adaptive radiotherapy planning. Although these methods are available for use on diagnostic machines, several challenges exist for implementing these functional MRI methods on the MRI-linear accelerators (linacs)...
September 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30224202/guidelines-for-clinical-target-volume-definition-for-perineural-spread-of-major-salivary-gland-cancers
#5
K Armstrong, J Ward, N M Hughes, A Mihai, A Blayney, C Mascott, R Kileen, J Armstrong
AIMS: Postoperative radiotherapy is the standard of care for resected major salivary cancers that are at risk of locoregional recurrence. Of the various histological subtypes, perineural invasion is most common in adenoidcystic carcinomas of the three major salivary glands - parotid, submandibular and sublingual. The clinical target volume (CTV) for these cases must include the relevant cranial nerve pathways at risk. A contouring atlas was devised for delineation of the CTV of the nerves supplying the major salivary glands...
September 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30220613/elective-management-of-the-neck-in-parotid-tumours
#6
B Ng-Cheng-Hin, J Glaholm, Z Awad, D M Gujral
AIMS: Management of the clinically node-negative (cN0) neck for parotid tumours remains controversial. Options include observation, elective neck dissection (END) or elective nodal irradiation (ENI). We reviewed the evidence for ENI on a background of current practice among UK clinical oncologists. MATERIALS AND METHODS: We carried out a systematic search of PubMed between 1 January 1980 and 31 December 2016. Articles on patients treated with parotidectomy and either END or ENI, and studies on nodal patterns of disease, were included...
September 13, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30217480/magnetic-resonance-guided-radiotherapy-can-we-justify-more-expensive-technology
#7
EDITORIAL
A C Tree, R Huddart, A Choudhury
No abstract text is available yet for this article.
September 11, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30213705/radical-s-radiotherapy-post-prostatectomy-current-and-future-practice
#8
EDITORIAL
J McGrane, F Mark, J Troup, C Parker, H Payne
No abstract text is available yet for this article.
September 10, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30213704/survey-on-adaptive-radiotherapy-practice
#9
LETTER
R Krishnatry, J Bhatia, V Murthy, J P Agarwal
No abstract text is available yet for this article.
September 10, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30213703/response-to-the-survival-time-of-8376-male-breast-cancer-patients
#10
LETTER
B A Wan, V Ganesh, L Zhang, P Sousa, L Drost, J Lorentz, D Vesprini, J Lee, E Rakovitch, F-I Lu, A Eisen, C Yee, H Lam, E Chow
No abstract text is available yet for this article.
September 10, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30209010/the-potential-value-of-mri-in-external-beam-radiotherapy-for-cervical-cancer
#11
A Cree, J Livsey, L Barraclough, M Dubec, T Hambrock, M Van Herk, A Choudhury, A McWilliam
The reference standard treatment for cervical cancer is concurrent chemoradiotherapy followed by magnetic resonance imaging (MRI)-guided brachytherapy. Improvements in brachytherapy have increased local control rates, but late toxicity remains high with rates of 11% grade ≥3. The primary clinical target volume (CTV) for external-beam radiotherapy includes the cervix and uterus, which can show significant inter-fraction motion. This means that generous margins are required to cover the primary CTV, increasing the radiation dose to organs at risk and, therefore, toxicity...
September 9, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30209009/the-road-map-for-proton-therapy
#12
LETTER
K Sikora
No abstract text is available yet for this article.
September 9, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30206022/solitary-fibrous-tumour-a-single-institution-retrospective-study-and-further-validation-of-a-prognostic-risk-assessment-system
#13
R B Friis, A Safwat, T Baad-Hansen, N Aggerholm-Pedersen
AIMS: Solitary fibrous tumour (SFT) is a rare mesenchymal-derived neoplasm that can arise in any anatomical location in the body. SFT rarely metastasises, but aggressive behaviour is seen in a minority of cases, and relapses can occur several years after treatment. It would be a clinical advantage if high-risk patients could be identified before treatment. MATERIALS AND METHODS: We retrospectively analysed a population-based cohort of SFT to describe treatment, outcome, prognostic factors and to further validate a previously published risk assessment tool (D-score) based on age, tumour size and mitotic index...
September 8, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30201277/risk-of-death-from-pneumocystis-jirovecii-after-curative-intent-radiotherapy-for-lung-cancer
#14
LETTER
J McAleese, L Mooney, G M Walls, R L Eakin, J Harney, G G Hanna
No abstract text is available yet for this article.
September 7, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30201276/adaptive-radiotherapy-enabled-by-mri-guidance
#15
A Hunt, V N Hansen, U Oelfke, S Nill, S Hafeez
Adaptive radiotherapy (ART) strategies systematically monitor variations in target and neighbouring structures to inform treatment-plan modification during radiotherapy. This is necessary because a single plan designed before treatment is insufficient to capture the actual dose delivered to the target and adjacent critical structures during the course of radiotherapy. Magnetic resonance imaging (MRI) provides superior soft-tissue image contrast over current standard X-ray-based technologies without additional radiation exposure...
September 7, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30197096/the-challenges-of-using-mri-during-radiotherapy
#16
A McWilliam, B Rowland, M van Herk
In this article we aim to introduce the main considerations in integrating magnetic resonance imaging (MRI) into the radiotherapy workflow. We will cover the use of MRI for improved delineation, considerations regarding MRI-only workflows, and the potential of functional imaging techniques. The challenges of implementing each of these will be discussed to ensure safe usage in radiotherapy.
September 6, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30197095/magnetic-resonance-image-guided-radiotherapy-mrigrt-a-4-5-year-clinical-experience
#17
L E Henke, J A Contreras, O L Green, B Cai, H Kim, M C Roach, J R Olsen, B Fischer-Valuck, D F Mullen, R Kashani, M A Thomas, J Huang, I Zoberi, D Yang, V Rodriguez, J D Bradley, C G Robinson, P Parikh, S Mutic, J Michalski
AIMS: Magnetic resonance image-guided radiotherapy (MRIgRT) has been clinically implemented since 2014. This technology offers improved soft-tissue visualisation, daily imaging, and intra-fraction real-time imaging without added radiation exposure, and the opportunity for adaptive radiotherapy (ART) to adjust for anatomical changes. Here we share the longest single-institution experience with MRIgRT, focusing on trends and changes in use over the past 4.5 years. MATERIALS AND METHODS: We analysed clinical information, including patient demographics, treatment dates, disease sites, dose/fractionation, and clinical trial enrolment for all patients treated at our institution using MRIgRT on a commercially available, integrated 0...
September 6, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30195605/mri-linear-accelerator-radiotherapy-systems
#18
G P Liney, B Whelan, B Oborn, M Barton, P Keall
The desire to utilise soft-tissue image guidance at the time of radiation treatment has led to the development of several hybrid magnetic resonance imaging (MRI) linear accelerators (linacs). These systems have the potential to realise the benefits of MRI on the treatment table with the ability of real-time motion management and adaption on a patient-specific basis. There are several MRI-linacs currently being implemented covering both low and high magnetic field strength and two beam-field orientations. Clinical trials have only recently begun with this technology, but their future use as standard radiotherapy practice seems assured...
September 5, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30078523/evaluation-of-a-novel-field-placement-algorithm-for-locoregional-breast-cancer-radiotherapy-including-the-internal-mammary-chain
#19
A Ranger, A Dunlop, P Shah, K Amin, D Henderson, F R Bartlett, C Knowles, B Brigden, C Lacey, E Donovan, E Harris, A M Kirby
AIMS: Irradiation of the internal mammary chain (IMC) is increasing following recently published data, but the need for formal delineation of lymph node volumes is slowing implementation in some healthcare settings. A field-placement algorithm for irradiating locoregional lymph nodes including the IMC could reduce the resource impact of introducing irradiation of the IMC. This study describes the development and evaluation of such an algorithm. MATERIALS AND METHODS: An algorithm was developed in which six points representing lymph node clinical target volume borders (based on European Society for Radiotherapy and Oncology consensus nodal contouring guidelines) were placed on computed tomography-defined anatomical landmarks and used to place tangential and nodal fields...
August 2, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/30075902/the-role-of-magnetic-resonance-imaging-in-brachytherapy
#20
H Tharmalingam, R Alonzi, P J Hoskin
The application of magnetic resonance imaging (MRI) in image-guided brachytherapy has expanded rapidly over the past two decades. In cervix cancer, significant improvements in overall survival, local control and long-term morbidity have been shown in patients treated with MRI-guided brachytherapy, changing clinical practice and directing an international approach to standardise the technique; unifying adaptive target volume definition and dose reporting. MRI-guided prostate brachytherapy has significantly improved the accuracy of tumour and organ-at-risk delineation, facilitating targeted implantation and dose optimisation...
July 31, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
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