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European Journal of Gastroenterology & Hepatology

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https://www.readbyqxmd.com/read/29049129/transjugular-intrahepatic-portosystemic-shunt-placement-before-abdominal-intervention-in-cirrhotic-patients-with-portal-hypertension-lessons-from-a-pilot-study
#1
Nadim Fares, Marie-Angèle Robic, Jean-Marie Péron, Fabrice Muscari, Philippe Otal, Bertrand Suc, Jean-Pierre Vinel, Christophe Bureau
BACKGROUND: Abdominal interventions are usually contraindicated in patients with cirrhosis and portal hypertension because of increased morbidity and mortality. Decreasing portal pressure with transjugular intrahepatic portosystemic shunt (TIPS) may improve patient outcomes. We report our experience with patients treated by neoadjuvant TIPS to identify those who would most benefit from this two-step procedure. PATIENTS AND METHODS: All patients treated by dedicated neoadjuvant TIPS between 2005 and March 2013 in two tertiary referral hospitals were included...
October 18, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29049128/changing-pathological-diagnosis-from-hyperplastic-polyp-to-sessile-serrated-adenoma-systematic-review-and-meta-analysis
#2
Yaron Niv
The WHO published a new classification of colonic polyps in 2010, including the group of serrated polyps, which can be divided into hyperplastic polyps (HP), traditional serrated adenomas, and sessile serrated adenomas (SSA) or polyps. To assess the rate of re-diagnosis of HP to SSA and to look for possible predictors for changing the diagnosis. English Medical literature searches were performed for 'reassessment' OR 'reclassification' AND 'hyperplastic polyp' OR 'sessile serrated adenoma' till 31 January 2017...
October 18, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29049127/hepatitis-c-virus-infection-and-risk-of-parkinson-s-disease-a-systematic-review-and-meta-analysis
#3
Karn Wijarnpreecha, Supavit Chesdachai, Veeravich Jaruvongvanich, Patompong Ungprasert
BACKGROUND/OBJECTIVE: Hepatitis C virus (HCV) infection is one of the most common infections worldwide. Recent epidemiologic studies have suggested that patients with HCV infection might be at an increased risk of Parkinson's disease. However, the data on this relationship remain inconclusive. This meta-analysis was conducted with the aim to summarize all available evidence. PATIENTS AND METHODS: A literature search was performed using MEDLINE and EMBASE database from inception to May 2017...
October 18, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29049126/shear-wave-elastography-for-the-assessment-of-liver-fibrosis-in-liver-transplant-recipients-treated-for-hepatitis-c-virus-recurrence
#4
David Korda, Zsuzsanna M Lenard, Zsuzsanna Gerlei, Zsuzsanna Jakab, Anita Haboub-Sandil, Laszlo Wagner, Marina Varga, Orsolya Cseprekal, Adrienn Marton, Denes Horvathy, Szabolcs Takacs, Attila Doros, Zoltan Mathe
OBJECTIVES: Direct-acting antiviral agents have revolutionized hepatitis C therapy, and are also found to be effective in the liver transplant setting. The extent of liver fibrosis influences patient management and is used to monitor therapeutic effects. Shear-wave elastography (SWE) is a relatively new imaging-based method that has not yet been studied extensively in liver transplant patients. Our aim was to study the effect of direct-acting antivirals in heaptitis C recurrence on liver stiffness determined by SWE...
October 18, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29035910/new-predictive-factors-of-poor-response-to-therapy-in-autoimmune-hepatitis-role-of-mean-platelet-volume
#5
Ahmed Abdel-Razik, Nasser Mousa, Sahar Zakaria, Rania Elhelaly, Rasha Elzehery, Khaled Zalata, Mahmoud Awad, Ahmed A Eldeeb, Mostafa Abdelsalam
BACKGROUND AND OBJECTIVES: The response to immunosuppressive therapy in autoimmune hepatitis (AIH) is a matter of debate. The aim of this work is to identify the histological, biochemical, and clinical predictive factors of incomplete response/treatment failure to the standard treatment (prednisone with or without azathioprine) in a well-characterized series of AIH Egyptian patients. PATIENTS AND METHODS: Of 49 AIH patients, only 36 patients completed this retrospective cohort study...
October 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29023321/antipsychotic-medication-and-oropharyngeal-dysphagia-systematic-review
#6
Marta Miarons Font, Laia Rofes Salsench
The association between antipsychotics (also known as neuroleptics) and oropharyngeal dysphagia (OD) has been suggested in several case reports. The purpose of this systematic review was to examine the effect of antipsychotic medication on OD. A systematic literature search was carried out according to PRISMA guidelines using the electronic databases Pubmed and Embase. In Pubmed, we used the MeSH terms 'antipsychotic agents' OR 'tranquilizing agents' combined with 'deglutition disorders' OR 'deglutition'. In Embase, we used the Emtree terms 'neuroleptic agents' combined with 'swallowing' OR 'dysphagia'...
October 11, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29023320/favorable-liver-cancer-mortality-to-incidence-ratios-of-countries-with-high-health-expenditure
#7
Chi-Chih Wang, Ming-Chang Tsai, Cheng-Ming Peng, Hsiang-Lin Lee, Hsuan-Yi Chen, Tzu-Wei Yang, Wen-Wei Sung, Chun-Che Lin
OBJECTIVE: Health expenditure is a marker associated with an advanced healthcare system, which contributes toward the good prognosis of patients. Mortality-to-incidence ratios (MIRs) are one of the predictors that reflect the prognosis of cancer patients. There remains some uncertainty on the correlation of MIRs of liver cancer with the health expenditure of countries. METHODS: We therefore analyzed the correlation of MIRs from the GLOBOCAN 2012 database with the WHO rankings and the total expenditures on health/gross domestic product from WHO by linear regression analyses...
October 11, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29023319/comparison-of-fenofibrate-and-pioglitazone-effects-on-patients-with-nonalcoholic-fatty-liver-disease
#8
Malek Yaghoubi, Sattar Jafari, Behnam Sajedi, Sepehr Gohari, Samira Akbarieh, Amir H Heydari, Maryam Jameshoorani
INTRODUCTION: Nonalcoholic fatty liver disease (NAFLD) is known to be a health-related problem; there is no proven treatment for NAFLD. However, a wide range of possible therapies have been proposed and studied. In the current study, we aimed to compare the therapeutic effects of fenofibrate and pioglitazone on NAFLD. PATIENTS AND METHODS: In this randomized clinical trial study (ethic number: ZUMS.REC.1393.133), patients with NAFLD and alanine aminotransferase in range of 1-1...
October 11, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29023318/comparison-of-gut-directed-hypnotherapy-and-unspecific-hypnotherapy-as-self-help-format-in-children-and-adolescents-with-functional-abdominal-pain-or-irritable-bowel-syndrome-a-randomized-pilot-study
#9
Marco D Gulewitsch, Angelika A Schlarb
OBJECTIVE: Psychosocial treatments for chronic abdominal pain in childhood or adolescence are effective, but time consuming and hardly available. In the present study, gut-directed hypnotherapy (GDHT) and unspecific hypnotherapy (UHT) were compared to evaluate the feasibility and efficacy of a hypnotherapeutic self-help intervention. PARTICIPANTS AND METHODS: Children/adolescents between 6 and 17 years of age with chronic abdominal pain were randomized to GDHT or UHT...
October 11, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29016470/efficacy-of-branched-chain-amino-acid-supplementation-and-walking-exercise-for-preventing-sarcopenia-in-patients-with-liver-cirrhosis
#10
Atsushi Hiraoka, Kojiro Michitaka, Daisuke Kiguchi, Hirofumi Izumoto, Hidetaro Ueki, Miho Kaneto, Shogo Kitahata, Toshihiko Aibiki, Tomonari Okudaira, Hideomi Tomida, Yuji Miyamoto, Hiroka Yamago, Yoshifumi Suga, Ryuichiro Iwasaki, Kenichiro Mori, Hideki Miyata, Eiji Tsubouchi, Masato Kishida, Tomoyuki Ninomiya, Shigeru Kohgami, Masashi Hirooka, Yoshio Tokumoto, Masanori Abe, Bunzo Matsuura, Yoichi Hiasa
BACKGROUND/AIM: Sarcopenia is recognized as a condition related to quality of life and prognosis in patients with chronic liver disease, although no useful strategy for improving muscle volume and strength has been established. Here, we evaluated the efficacy of supplementation with branched-chain amino acid (BCAA) administration and walking exercise. PATIENTS AND METHODS: From December 2015 to July 2016, 33 Japanese outpatients with liver cirrhosis were enrolled (median: 67 years, HCV : HBV : alcohol : others=26 : 2 : 2 : 3, male : female=13 : 20, Child-Pugh A : B=30 : 3)...
October 9, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28984679/influence-of-laboratory-related-and-endoscopy-related-factors-on-the-assessment-of-serum-pepsinogens-and-gastrin-17
#11
Elisabetta Goni, Marino Venerito, Christian Schulz, Jochen Weigt, Cosima Langner, Alexander Link, Peter Malfertheiner
BACKGROUND AND AIM: Serum pepsinogen I (PGI) and pepsinogen II (PGII) are noninvasive parameters in the detection of atrophic gastritis. The diagnostic add-on value of serum gastrin-17 (G-17) remains uncertain. The aim of this study was to assess the stability of these serum parameters over time and to evaluate the influence of clinical factors, such as upper gastrointestinal (GI) endoscopy and bowel cleansing, on serum PGI, PGII, and G-17 assessment. PATIENTS AND METHODS: A prospective study was carried out in healthy individuals and patients...
October 3, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28984678/effect-of-branched-chain-amino-acid-supplements-on-muscle-strength-and-muscle-mass-in-patients-with-liver-cirrhosis
#12
Haruki Uojima, Seiko Sakurai, Hisashi Hidaka, Takeshi Kinbara, Ji Hyun Sung, Chikamasa Ichita, Shinnosuke Tokoro, Sakue Masuda, Akiko Sasaki, Kazuya Koizumi, Hideto Egashira, Makoto Kako, Shuzo Kobayashi
OBJECTIVE: The aim of this study was to assess the effect of branched-chain amino acid (BCAA) supplements on muscle strength and muscle mass in patients with liver cirrhosis. PATIENTS AND METHODS: We carried out a single-center, prospective study of adult cirrhotic patients receiving nutrition therapy at Shonan Kamakura General Hospital. A 28-day pretreatment observation period was followed by a 24-week treatment period. Patients who fulfilled the treatment criteria received one package of oral BCAA supplement powder twice a day and the response was evaluated...
October 3, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28957872/utility-of-post-liver-transplantation-meld-and-delta-meld-in-predicting-early-and-late-mortality
#13
Talaat Zakareya, Mohammed Abbasy, Wael Abdel-Razek, Hussein Elsiesy, Faisal Abal Khail, Mohammed Al Sebayel, Imam Waked
INTRODUCTION: The performance of early post-liver transplantation (post-LT) model for end-stage liver disease (MELD) or even its dynamic changes over time (ΔMELD) in predicting the mortality after LT is still controversial. AIM: The aim of this study was to assess the ability of absolute and ΔMELD calculated at days 7 and 30 after LT to predict 1- and 5-year mortality. PATIENTS AND METHODS: Data of 209 consecutive patients who underwent LT in two centers were reviewed...
September 27, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28957871/comparison-of-correlations-between-lipid-profile-and-different-computed-tomography-fatty-liver-criteria-in-the-setting-of-incidentally-noted-fatty-liver-on-computed-tomography-examinations
#14
Anugayathri Jawahar, Beverly Gonzalez, Neelam Balasubramanian, William Adams, Ari Goldberg
PURPOSE: The aim of this study was to compare the correlations between computed tomography (CT) criteria for hepatic steatosis and lipid profile values when hepatic steatosis is incidentally detected. PARTICIPANTS AND METHODS: This is an institutional Review Board-approved, HIPPA-compliant, retrospective study of abdominal CT scans in 200 randomly selected patients who had either nonenhanced CT (NECT) or contrast-enhanced CT (CECT) studies with reported fatty liver...
September 27, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28953003/vitamin-b12-deficiency-in-inflammatory-bowel-disease-a-prospective-observational-pilot-study
#15
Robert Battat, Uri Kopylov, Joshua Byer, Maida J Sewitch, Elham Rahme, Hacene Nedjar, Elana Zelikovic, Serge Dionne, Talat Bessissow, Waqqas Afif, Paula J Waters, Ernest Seidman, Alain Bitton
BACKGROUND AND AIM: Diagnostic and management guidelines for vitamin B12 (cobalamin, Cbl) deficiency in inflammatory bowel disease (IBD) are lacking. True deficiency is defined as Cbl concentrations below reference range combined with elevated methylmalonic acid (MMA) concentrations. Studies analyzing Cbl status in IBD use only Cbl concentrations without confirmatory MMA. This study aims to determine the proportion of IBD patients with Cbl concentrations below reference range and their predisposing clinical and genetic characteristics...
September 25, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28953002/sofosbuvir-and-daclatasvir-plus-ribavirin-treatment-improve-liver-function-parameters-and-clinical-outcomes-in-egyptian-chronic-hepatitis-c-patients
#16
Mohamed S Mohamed, Amr S Hanafy, Mohamed A A Bassiony, Samia Hussein
BACKGROUND AND AIMS: Interferon-free direct-acting antivirals (DAA) combination therapies, including sofosbuvir (SOF) and daclatasvir (DCV) therapy, eradicate chronic hepatitis C virus (HCV) in a high percentage of patients, but its impact on improvements in liver function is unclear. The aim of this study was to investigate the changes in clinical and biochemical parameters reflecting liver function and general status in those who achieved HCV eradication by DAA. PATIENTS AND METHODS: From March 2016 to October 2016, 374 chronic hepatitis C patients were enrolled for this prospective, observational study and received SOF, DCV with ribavirin, to evaluate the changes in liver function parameters, international normalized ratio, complete blood count, model for end-stage liver disease, and Child-Turcotte-Pugh scores after achieving a sustained virological response 12 weeks after treatment...
September 25, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28914695/autoimmune-acute-liver-failure-and-seronegative-autoimmune-liver-disease-in-children-are-they-different-from-classical-disease
#17
Vikas Jain, Anshu Srivastava, Surender K Yachha, Niraj Kumari, Rachana Kathuria, Moinak S Sarma, Ujjal Poddar, Narendra Krishnani
OBJECTIVES: Presentation as autoimmune acute liver failure (AI-ALF) and seronegative autoimmune liver disease (SN-AILD) represents two uncommon variants of AILD. We compared the clinical profile and outcome of AI-ALF with autoimmune-non-acute liver failure (AI-non-ALF) and also SN-AILD with seropositive autoimmune liver disease (SP-AILD). MATERIALS AND METHODS: Children managed as AI-ALF and AI-non-ALF including SN-AILD and SP-AILD were enrolled and compared. AI-non-ALF was diagnosed by simplified diagnostic criteria and AI-ALF by Pediatric Acute Liver Failure Study Group criteria with positive autoantibody, exclusion of other etiologies, elevated immunoglobulin G and histology when available...
September 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28914694/the-association-of-nonalcoholic-steatohepatitis-and-obstructive-sleep-apnea
#18
Mohammad M Asfari, Fadi Niyazi, Rocio Lopez, Srinivasan Dasarathy, Arthur J McCullough
BACKGROUND AND AIM: The association between obstructive sleep apnea (OSA) and abnormal liver enzymes has been reported in multiple studies. The existing literature regarding the relationship between OSA and nonalcoholic steatohepatitis (NASH) is conflicting. Thus we aimed to determine the relationship between OSA and NASH from a large database. PATIENTS AND METHODS: A cross-sectional study was performed using the 2012 Nationwide Inpatient Sample. We identified adult patients (18-90 years) who had a diagnosis of OSA using the International Classification of Diseases 9th version codes...
September 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28953583/helicobacter-pylori-among-patients-with-cirrhosis-incidence-or-prevalence
#19
Rinaldo Pellicano
No abstract text is available yet for this article.
November 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28953582/the-relationship-between-postoperative-complications-and-long-term-survival-after-liver-resection-of-hepatocellular-carcinoma
#20
Zheng Wang, Yi-Sheng Huang, Jun Han, Chao Li, Tian Yang
No abstract text is available yet for this article.
November 2017: European Journal of Gastroenterology & Hepatology
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