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Journal of Dermatological Treatment

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https://www.readbyqxmd.com/read/28322070/enhancing-clinical-communication-in-dermatologists-a-personalized-educational-intervention
#1
Zoi Tsimtsiou, Charitini Stavropoulou, Noni Papastefanou, Christos Lionis
OBJECTIVES: Effective communication is a vital component of patient-centered consultations with favourable treatment outcomes. This study aimed in testing the effectiveness of a personalized, communication training program for dermatologists in their practices. METHODS: Fifteen dermatologists were offered the educational intervention NO.TE.S. (Non Technical Skills). Depending on the dermatologists' needs, seven to nine sessions with a 60-minute duration were performed, focusing on: patient-centered care, principles of Neurolinguistic Programming, a guide to the medical interview, principles of motivational interviewing and self-care...
March 21, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28320220/a-combination-of-yiqiqubai-granule-and-308-nm-excimer-laser-in-treatment-of-segmental-vitiligo-a-prospective-study-of-233-patients
#2
Chengzhong Zhang, Le Zhou, Jie Huang, Weimin Shi
OBJECTIVE: To study the effect of Yiqiqubai granule combined with 308-nm excimer laser treatment for segmental vitiligo (SV). METHODS: A prospective research was performed in 233 patients with SV treated in Shanghai General Hospital from 11 February 2015 to 25 August 2016, they were divided into group A (n = 75), group B (n = 78) and group C (n = 80) according to the random number table. Group A was treated with Yiqiqubai granule, group B treated with 308-nm excimer laser and group C treated with combined treatments...
March 21, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28320227/sublingual-immunotherapy-in-patients-with-latex-allergy-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#3
Kannan Sridharan, Gowri Sivaramakrishnan
Latex allergy (LA) is a commonly observed entity for which sublingual immunotherapy (SLIT) has been shown to be effective in many small randomized clinical trials. The present study was conducted with an aim of systematically reviewing the existing literature on the efficacy and safety of SLIT in patients with LA and to apply the principles of meta-analysis. A search for randomized controlled trials with appropriate search strategy in PubMed and CENTRAL was conducted. Studies with documented clinical history of LA and SLIT administered in any dose, duration and regimen compared with placebo were included...
March 20, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28320215/correction-to-psoriasis-patients-with-psoriasis-area-and-severity-index-pasi-90-response-achieve-greater-health-related-quality-of-life-improvements-than-those-with-pasi-75-89-response-results-from-two-phase-3-studies-of-secukinumab
#4
https://www.readbyqxmd.com/read/28320213/rethinking-costs-of-psoriasis-10-of-patients-account-for-nearly-40-of-healthcare-expenditures-among-enrollees-with-psoriasis-in-a-u-s-health-plan
#5
April W Armstrong, Yang Zhao, Vivian Herrera, Yunfeng Li, Tim Bancroft, Michael Hull, Aylin Altan
OBJECTIVE: To examine characteristics, healthcare utilization and costs among patients with psoriasis who have high medical costs. METHODS: This is a retrospective study of patients with psoriasis with continuous enrollment from 1 January 2011 to 31 December 2013 in a large US health plan. Total paid 2012 healthcare costs excluding biologics (to identify costliest not due to biologic costs) were used to create cohorts representing the top 10% (T10) and bottom 90% (B90) of expenditures...
March 20, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28318360/axillary-hyperhidrosis-a-focused-review
#6
Jason E Sammons, Amor Khachemoune
Axillary hyperhidrosis is characterized by an increased amount of sweat production, localized to the armpits, to compensate for environmental conditions and to control thermoregulation. It affects about 3.12% of the US population. It has a significant effect on one's psychological and physical health, as well as one's occupational life. The objective of this paper is to review the epidemiology, clinical presentation, pathophysiology, histology, and genetics, and management and treatment of axillary hyperhidrosis...
March 20, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28318351/retinoids-a-journey-from-the-molecular-structures-and-mechanisms-of-action-to-clinical-uses-in-dermatology-and-adverse-effects
#7
Samar Khalil, Tara Bardawil, Carla Stephan, Nadine Darwiche, Ossama Abbas, Abdul Ghani Kibbi, Georges Nemer, Mazen Kurban
Retinoids are a class of compounds derived from vitamin A or have structural and/or functional similarity with vitamin A. They are classified into three generations based on their molecular structures. Inside the body, retinoids bind to several classes of proteins including retinoid-binding proteins and retinoid nuclear receptors. This eventually leads to the activation of specific regulatory regions of DNA - called the retinoic acid response elements - involved in regulating cell growth, differentiation and apoptosis...
March 20, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28301978/is-photodynamic-therapy-a-relevant-therapeutic-option-in-refractory-benign-familial-pemphigus-hailey-hailey-disease-a-series-of-8-patients
#8
M Alsahli, A Debu, C Girard, D Bessis, A Du Thanh, B Guillot, O Dereure
INTRODUCTION/BACKGROUND: Treatment of benign familial pemphigus or Hailey-Hailey disease (HHD), a rare inherited condition associated with a significant impairment of quality of life, is often challenging and disappointing with frequent relapses and infectious complications. Topical photodynamic therapy (PDT) may offer new perspectives in this difficult setting Material and methods: Eight patients with long-lasting HHD lesions refractory to multiple treatments were treated on at least one involved site with PDT using methyl-amino levulinate with a standardized protocol of 3 sessions of irradiation separated by 3-week intervals...
March 17, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28285560/prospective-pilot-study-on-combined-use-of-pulsed-dye-laser-and-1-topical-rapamycin-for-treatment-of-non-facial-cutaneous-capillary-malformation
#9
Eun Jin Doh, Jungyoon Ohn, Min Ji Kim, Young Gull Kim, Soyun Cho
BACKGROUND: The regeneration or revascularization of blood vessels after pulsed dye laser (PDL) treatment is one of the causes of treatment failures of cutaneous capillary malformations (CM). Recently, topical administration of rapamycin was introduced as a possible adjunctive therapeutic option to minimize post-laser revascularization in facial CM. OBJECTIVES: We evaluated the effect of combined use of 1% topical rapamycin with PDL compared to PDL alone in cutaneous CM of trunk or extremities and tried to identify the optimal duration of topical rapamycin application...
March 13, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28274164/impact-of-immunogenicity-on-response-to-anti-tnf-therapy-in-moderate-to-severe-plaque-psoriasis-results-of-the-predir-study
#10
Mariano Ara-Martín, Pedro Herranz Pinto, Dora Pascual-Salcedo
PURPOSE: This study was conducted to examine the relationship between loss of clinical response to anti-tumor necrosis factor (TNF) therapy and the production of anti-drug antibodies (ADAs) and the potential effects of biologic immunogenicity. MATERIALS AND METHODS: This observational, non-interventional, cross-sectional study included patients with moderate-to-severe plaque psoriasis and secondary failure of adalimumab, etanercept and infliximab who were seen in the clinical practice setting...
March 8, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28271918/platelet-rich-plasma-for-treatment-of-nonscarring-hair-loss-systematic-review-of-literature
#11
Azin Ayatollahi, Hamed Hosseini, Jaleh Gholami, Babak Mirminachi, FaridHossein Firooz, Alireza Firooz
BACKGROUND: Although there are many studies showing the role of platelet rich plasma (PRP) in bone grafts, teeth osteosynthesis, and wound healing, there have been little peer reviewed studies about the safety and efficacy of PRP application in the treatment of hair loss. MATERIALS AND METHODS: In this systematic review, we searched Ovid Medline, Scopus and Web of Knowledge till November 2015 for human studies evaluating the efficacy of PRP for the treatment of noncicatricial alopecia...
March 8, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28266882/high-grade-follicular-lymphoma-in-a-patient-receiving-adalimumab-and-methotrexate-for-pityriasis-rubra-pilaris
#12
E Nic Dhonncha, K Fadalla, B Moriarty, D Gibbons, C D Collins, A Fabre, P Collins
No abstract text is available yet for this article.
March 7, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28266243/psoriasis-patients-with-psoriasis-area-and-severity-index-pasi-90-response-achieve-greater-health-related-quality-of-life-improvements-than-those-with-pasi-75-89-response-results-from-two-phase-3-studies-of-secukinumab
#13
Boni E Elewski, Lluís Puig, Margaret Mordin, Isabelle Gilloteau, Bintu Sherif, Todd Fox, Ari Gnanasakthy, Charis Papavassilis, Bruce E Strober
BACKGROUND: The emergence of new biological therapies showing high and sustained level of Psoriasis Area and Severity Index (PASI) 90 response has provided the possibility of both greater skin clearance and increased quality of life (QOL). OBJECTIVE: To evaluate the association of greater response in skin clearance with improvements in skin-related QOL up to 52 weeks. METHODS: Subjects achieving various levels of skin clearance (PASI 90-100 or PASI 75-89) and Dermatology Life Quality Index (DLQI) (0/1) response were compared using ERASURE and FIXTURE trial data...
March 7, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28264612/a-dose-finding-trial-with-a-novel-ingenol-derivative-ingenol-disoxate-leo-43204-for-field-treatment-of-actinic-keratosis-on-full-face-or-250cm-2-on-the-chest
#14
Marc Bourcier, Linda Stein Gold, Lyn Guenther, Camilla M Andreassen, Johan Selmer, Gary Goldenberg
PURPOSE: Actinic keratoses (AKs) may progress to squamous cell carcinoma and can occur in cancerized fields as sub-clinical and clinically visible lesions. Ingenol disoxate gel is a topical field therapy for AK. This Phase I/II trial aimed to assess the safety and efficacy of ingenol disoxate on full face or chest in patients with AKs. MATERIALS AND METHODS: Part 1 was a phase-I, open-label, dose-escalation trial investigating the maximum tolerated dose of ingenol disoxate...
March 7, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28147886/development-and-psychometric-evaluation-of-the-self-assessment-of-psoriasis-symptoms-saps-clinical-trial-and-the-saps-real-world-patient-reported-outcomes
#15
April W Armstrong, Benjamin Banderas, Catherine Foley, Jonathan Stokes, Murali Sundaram, Alan L Shields
OBJECTIVE: The Self-Assessment of Psoriasis Symptoms- Clinical Trials (SAPS-CT), and SAPS- Real World (SAPS-RW) were simultaneously created to assess the experience of plaque psoriasis in two unique contexts. METHODS: Qualitative and quantitative research was conducted in four phases: concept elicitation; questionnaire construction; content evaluation; and psychometric evaluation. RESULTS: Following concept elicitation, 18 concepts were selected to inform questionnaire construction of the SAPS-CT and -RW...
February 2, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28147884/atlas-of-genodermatoses-second-edition-a-colorful-review-of-genodermatoses
#16
Erin T Landis
No abstract text is available yet for this article.
February 2, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28145790/interleukin-31-pathway-and-its-role-in-atopic-dermatitis-a-systematic-review
#17
Mohammed D Saleem, Elias Oussedik, Veronica D'Amber, Steven R Feldman
BACKGROUND: Atopic dermatitis, a chronic inflammatory disease, has a lifetime prevalence of 10-20%. Atopic dermatitis reduces quality of life, primarily due to pruritus. Interleukin-31 and its target receptor are newly discovered entities that are involved in pruritus. PURPOSE: To summarize the current understanding of interleukin-31 and its role in atopic dermatitis, potential therapeutic interventions, and future prospects. METHODS: A systematic review was designed to identify articles related to interleukin-31 and its role in pruritus...
February 1, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28142293/a-case-report-of-coup-de-sabre-patient-with-hair-transplantation
#18
Yeqin Dai, Ai-E Xu, Junhua He
BACKGROUND: Treatment of coup de sabre must remain conservative until the disease is no longer in an active state. When activity has ceased, some operative intervention is safe and effective for the correction of deformity. While hair transplantation showed high survival rates for the correction of cicatricial alopecia, it has rarely reported to be performed for the correction of coup de sabre. OBJECTIVE: To assess the therapeutic possibility of hair transplantation for the correction of coup de sabre...
January 31, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28132580/real-world-outcomes-in-2-646-psoriasis-patients-one-in-five-has-pasi-%C3%A2-10-and-or-dlqi-%C3%A2-10-under-ongoing-systemic-therapy
#19
J M Norlin, P S Calara, U Persson, M Schmitt-Egenolf
Background Although biologics introduced a new era in psoriasis care when available a decade ago, it is unclear to what extent the available systemic treatments treat patients adequately. Objective To analyse the clinical severity and quality of life of the psoriasis population in Sweden treated with systemics. Methods Data included 2,646 patients from the Swedish Registry for Systemic Treatment of Psoriasis. Average Psoriasis Area and Severity Index (PASI), Dermatology Life Quality Index (DLQI), and EQ-5D were reported...
January 30, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28132575/dermatologic-radiotherapy-in-the-treatment-of-extensive-basal-cell-carcinomas-a-retrospective-study
#20
R Piccinno, S Benardon, F M Gaiani, M Rozza, M Caccialanza
BACKGROUND: The increase of the number of new cases for year of basal cell carcinoma (BCC) has brought also an increase of BCC difficult to treat (extensive, locally advanced and high risk forms). OBJECTIVE: To evaluate retrospectively the results obtained with dermatologic radiotherapy (RT) for better defining the indications respect to new emerging treatments. METHODS: A series of extensive 115 BCC treated with RT from 1977 to 2014 were selected for the study, since endowed with histological diagnosis on the amount of 181 extensive BCC...
January 29, 2017: Journal of Dermatological Treatment
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