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AIDS Care

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https://www.readbyqxmd.com/read/28158952/a-qualitative-study-of-thai-hiv-positive-young-men-who-have-sex-with-men-and-transgender-women-demonstrates-the-need-for-ehealth-interventions-to-optimize-the-hiv-care-continuum
#1
Tarandeep Anand, Chattiya Nitpolprasert, Stephen J Kerr, Kathryn E Muessig, Sangusa Promthong, Nitiya Chomchey, Lisa B Hightow-Weidman, Prachya Chaiyahong, Praphan Phanuphak, Jintanat Ananworanich, Nittaya Phanuphak
In Thailand, young men who have sex with men (YMSM) and transgender women (TG) are disproportionately affected by HIV and have suboptimal care continuum outcomes. Although Thai YMSM and young TG are early adopters of emerging technologies and have high Internet and technology access and utilization, the potential of technology has not been harnessed to optimize the HIV treatment cascade. We interviewed 18 behaviorally HIV-infected YMSM and young TG regarding care challenges, identified how eHealth could address care needs, and elicited preferences for eHealth interventions...
February 3, 2017: AIDS Care
https://www.readbyqxmd.com/read/28150510/quality-of-life-in-an-italian-cohort-of-people-living-with-hiv-in-the-era-of-combined-antiretroviral-therapy-evidence-from-i-a-n-u-a-study-investigation-on-antiretroviral-therapy
#2
A Venturini, G Cenderello, A Di Biagio, B Giannini, M Ameri, M Giacomini, M Montefiori, M Setti, G Mazzarello, C Merlano, P Orcamo, C Viscoli, G Cassola
The aims of this study were to assess the Health Related Quality of Life (HRQoL) of People Living with HIV/AIDS (PLWHA) who attend outpatient services in Genoa, Italy, and to evaluate the relationship between HRQoL and clinical factors, primarily: CD4+ cell count, viral load and HIV-Hepatitis C Virus (HCV) coinfection. A cross-sectional study was performed involving a sample of 943 consecutive patients. Firstly the EuroQol-Five Dimensions-Three Level (EQ-5D-3L) self-reported questionnaire was used to evaluate HRQoL, while socio-demographic information was collected using a separate self-administered questionnaire...
February 2, 2017: AIDS Care
https://www.readbyqxmd.com/read/28150501/effectiveness-of-peer-led-interventions-to-increase-hiv-testing-among-men-who-have-sex-with-men-a-systematic-review-and-meta-analysis
#3
Sylvia Shangani, Daniel Escudero, Kipruto Kirwa, Abigail Harrison, Brandon Marshall, Don Operario
HIV testing constitutes a key step along the continuum of HIV care. Men who have sex with men (MSM) have low HIV testing rates and delayed diagnosis, especially in low-resource settings. Peer-led interventions offer a strategy to increase testing rates in this population. This systematic review and meta-analysis summarizes evidence on the effectiveness of peer-led interventions to increase the uptake of HIV testing among MSM. Using a systematic review protocol that was developed a priori, we searched PubMed, PsycINFO and CINAHL for articles reporting original results of randomized or non-randomized controlled trials (RCTs), quasi-experimental interventions, and pre- and post-intervention studies...
February 2, 2017: AIDS Care
https://www.readbyqxmd.com/read/28147708/tolerability-of-central-nervous-system-symptoms-among-hiv-1-infected-efavirenz-users-analysis-of-patient-electronic-medical-record-data
#4
Lisa Rosenblatt, Michael S Broder, Tanya G K Bentley, Eunice Chang, Sheila R Reddy, Elya Papoyan, Joel Myers
Efavirenz (EFV) is a non-nucleoside reverse transcriptase inhibitor indicated for treatment of HIV-1 infection. Despite concern over EFV tolerability in clinical trials and practice, particularly related to central nervous system (CNS) adverse events, some observational studies have shown high rates of EFV continuation at one year and low rates of CNS-related EFV substitution. The objective of this study was to further examine the real-world rate of CNS-related EFV discontinuation in antiretroviral therapy naïve HIV-1 patients...
February 1, 2017: AIDS Care
https://www.readbyqxmd.com/read/28147705/-it-s-about-my-life-facilitators-of-and-barriers-to-isoniazid-preventive-therapy-completion-among-people-living-with-hiv-in-rural-south-africa
#5
Karen B Jacobson, Linda Niccolai, Nonhle Mtungwa, Anthony P Moll, Sheela V Shenoi
Despite the recent rollout of Isoniazid Preventive Therapy (IPT) to prevent TB in people living with HIV in South Africa, adherence and completion rates are low. To explore barriers to IPT completion in rural KwaZulu-Natal, South Africa, we conducted individual semi-structured interviews among 30 HIV patients who had completed or defaulted IPT. Interview transcripts were analyzed according to the framework method of qualitative analysis. Facilitators of IPT completion included knowledge of TB and IPT, accepting one's HIV diagnosis, viewing IPT as similar to antiretroviral therapy, having social support in the community and the clinic, trust in the healthcare system, and desire for health preservation...
February 1, 2017: AIDS Care
https://www.readbyqxmd.com/read/28147704/pre-exposure-prophylaxis-prescribing-and-retention-in-care-among-heterosexual-women-at-a-community-based-comprehensive-sexual-health-clinic
#6
Oni J Blackstock, Viraj V Patel, Uriel Felsen, Connie Park, Sachin Jain
In the United States, heterosexual women account for 20% of new HIV infections. As a user-controlled HIV prevention method, pre-exposure prophylaxis (PrEP) has substantial potential to reduce new infections among women. However, among women, PrEP is vastly underutilized. To guide efforts to increase women-at-risk's PrEP use, we sought to describe the characteristics of women prescribed PrEP as well as their retention in PrEP care. We conducted a chart review of women who received care at a comprehensive sexual health clinic within a large urban health care system...
February 1, 2017: AIDS Care
https://www.readbyqxmd.com/read/28132544/growing-challenges-for-hiv-programmes-in-asia-clinic-population-trends-2003-2013
#7
Nicole L De La Mata, Nagalingeswaran Kumarasamy, Penh Sun Ly, Oon Tek Ng, Kinh Van Nguyen, Tuti Parwati Merati, Man Po Lee, Cuong Duy Do, Jun Yong Choi, Jeremy L Ross, Matthew G Law
The scale-up of antiretroviral therapy (ART) has led to a substantial change in the clinical population of HIV-positive patients receiving care. We describe the temporal trends in the demographic and clinical characteristics of HIV-positive patients initiating ART in 2003-13 within an Asian regional cohort. All HIV-positive adult patients that initiated ART between 2003 and 2013 were included. We summarized ART regimen use, age, CD4 cell count, HIV viral load, and HIV-related laboratory monitoring rates during follow-up by calendar year...
January 29, 2017: AIDS Care
https://www.readbyqxmd.com/read/28132520/pregnancy-and-linkage-to-care-among-women-diagnosed-with-hiv-infection-in-61-cdc-funded-health-departments-in-the-united-states-2013
#8
Lauren F FitzHarris, Natasha D Hollis, Steven R Nesheim, Julia L Greenspan, Erica K Dunbar
Timely linkage to HIV care (LTC) following an HIV diagnosis is especially important for pregnant women with HIV to prevent perinatal transmission and improve maternal health. However, limited data are available on LTC among U.S. pregnant women. Our analysis aimed to identify HIV diagnoses among childbearing age (CBA) women (15-44 years old) by pregnancy status and to compare LTC of HIV-infected pregnant women to HIV-infected non-pregnant women. We analyzed 2013 CDC-funded HIV testing data from 61 health departments and 151 directly funded community-based organizations among CBA women...
January 29, 2017: AIDS Care
https://www.readbyqxmd.com/read/28132519/alcohol-use-and-immune-reconstitution-among-hiv-infected-patients-on-antiretroviral-therapy-in-nairobi-kenya
#9
Anthony Cagle, Christine McGrath, Barbra A Richardson, Dennis Donovan, Sameh Sakr, Nelly Yatich, Richard Ngomoa, Agnes Chepngeno Langat, Grace John-Stewart, Michael H Chung
Studies on the effects of alcohol use on HIV disease progression have been contradictory, with at least one study finding a positive effect of low alcohol consumption on CD4 count. In addition, most such studies have taken place in the developed West. We investigated the association between alcohol use and immune reconstitution through CD4 count response among HIV-infected individuals on antiretroviral therapy (ART) at an urban sub-Saharan African clinic. This was a retrospective cohort study of treatment-naïve HIV-infected adults initiating ART in Nairobi, Kenya and followed for 12 months between January 2009 and December 2012...
January 29, 2017: AIDS Care
https://www.readbyqxmd.com/read/28132516/using-a-social-ecological-framework-to-characterize-the-correlates-of-hiv-among-men-who-have-sex-with-men-in-lom%C3%A3-togo
#10
Horacio Ruiseñor-Escudero, Ashley Grosso, Sosthenes Ketende, Vincent Pitche, Anato Simplice, Jules Tchalla, Dometo Sodji, Ben Liestman, Laurent Kapesa, Stefan Baral
In the mixed and concentrated HIV epidemics of West Africa, the relative disproportionate burden of HIV among men who have sex with men (MSM) compared to other reproductive-age men is higher than that observed in Southern and Eastern Africa. Our aim is to describe the correlates of HIV infection among MSM living in Lomé, Togo, using the Modified Social Ecological Model (MSEM). A total of 354 MSM ≥18 years of age were recruited using respondent driven sampling (RDS) for a cross-sectional survey in Lomé, Togo...
January 29, 2017: AIDS Care
https://www.readbyqxmd.com/read/28127989/psychiatric-symptom-burden-in-older-people-living-with-hiv-with-and-without-cognitive-impairment-the-ucsf-hiv-over-60-cohort-study
#11
Benedetta Milanini, Stephanie Catella, Brandon Perkovich, Pardis Esmaeili-Firidouni, Lauren Wendelken, Robert Paul, Meredith Greene, Robin Ketelle, Victor Valcour
Psychiatric comorbidities are common in people living with HIV (PLWH) and adversely affect life satisfaction, treatment adherence and disease progression. There are few data to inform the burden of psychiatric symptoms in older PLWH, a rapidly growing demographic in the U.S. We performed a cross-sectional analysis to understand the degree to which symptom burden was associated with cognitive disorders in PLWH over age 60. Participants completed a standardized neuropsychological battery and were assigned cognitive diagnoses using Frascati criteria...
January 27, 2017: AIDS Care
https://www.readbyqxmd.com/read/28127988/staphylococcus-aureus-nasal-colonization-among-hiv-infected-adults-in-botswana-prevalence-and-risk-factors
#12
Michael J A Reid, Andrew P Steenhoff, Naledi Mannathoko, Charles Muthoga, Erin McHugh, Eric L Brown, Rebecca S B Fischer
We sought to determine the clinical and epidemiologic determinants of Staphylococcus aureus nasal colonization in HIV-infected individuals at two outpatient centers in southern Botswana. Standard microbiologic techniques were used to identify S. aureus and methicillin-resistant S. aureus (MRSA). In a sample of 404 HIV-infected adults, prevalence of S. aureus nasal carriage was 36.9% (n = 152) and was associated with domestic overcrowding and lower CD4 cell count. MRSA prevalence was low (n = 13, 3.2%), but more common among individuals with asthma and eczema...
January 27, 2017: AIDS Care
https://www.readbyqxmd.com/read/28127987/factors-associated-with-medication-adherence-in-patients-with-human-immunodeficiency-virus-in-south-korea
#13
Hye Jin Yang, Ji Hwan Bang
This study aimed to identify the factors associated with medication adherence in human immunodeficiency virus (HIV) patients in South Korea. A cross-sectional study was conducted from six hospitals participating in the Nationwide Specialized Counseling Program for HIV infected patients from 22 February to 10 May 2010. A total of 300 HIV patients have completed a self-administered questionnaire. Among 300 patients, 230 patients had above 95% medication adherence. Binary logistic regression analysis revealed that having medical insurance (p = ...
January 27, 2017: AIDS Care
https://www.readbyqxmd.com/read/28114801/association-of-cd4-t-cell-subpopulations-and-psychological-stress-measures-in-women-living-with-hiv
#14
Kristina E Rehm, Deborah Konkle-Parker
Psychological stress is a known immunomodulator. In individuals with HIV, depression, the most common manifestation of increased psychological stress, can affect immune function with lower CD4+ T cell counts correlating with higher levels of depression. It is unknown how other forms of psychological stress can impact immune markers in people living with HIV. We conducted a cross-sectional study to determine how CD4+ T cell subpopulations correlated with different forms of psychological stress. We recruited 50 HIV-positive women as part of the Women's Interagency HIV Study...
January 24, 2017: AIDS Care
https://www.readbyqxmd.com/read/28114813/reproductive-health-counseling-delivered-to-women-living-with-hiv-in-the-united-states
#15
Runa H Gokhale, Heather Bradley, John Weiser
Advances in antiretroviral therapy (ART) and reproductive technologies have made transmission of HIV to partners and infants almost completely preventable. Comprehensive reproductive health counseling (CRHC) is an important component of care for women living with HIV, but few women report discussing reproductive health with an HIV care provider. We surveyed a probability sample of U.S. HIV care providers during 2013-2014. Of 2023 eligible providers, 1234 responded (64% adjusted provider response rate). We estimated the percentage delivering CRHC to their female patients...
January 23, 2017: AIDS Care
https://www.readbyqxmd.com/read/28114789/evaluation-of-opt-out-inpatient-hiv-screening-at-an-urban-teaching-hospital
#16
Georgina Osorio, Martin Hoenigl, Jennifer Quartarolo, Khamisah Barger, Sheldon R Morris, Sharon L Reed, Joshua Lee, Susan J Little
This study evaluated opt-out inpatient HIV screening delivered by admitting physicians, and compared number of HIV tests and diagnoses to signs and symptoms-directed HIV testing (based on physician orders) in the emergency department (ED). The opt-out inpatient HIV screening program was conducted over a one year period in patients who were admitted to the 386-bed University of California San Diego (UCSD) teaching hospital. Numbers of HIV tests and diagnoses were compared to those observed among ED patients who underwent physician-directed HIV testing during the same time period...
January 23, 2017: AIDS Care
https://www.readbyqxmd.com/read/28110552/factors-associated-with-the-quality-of-life-of-people-living-with-hiv-in-finland
#17
Nuno Nobre, Marco Pereira, Risto P Roine, Harri Sintonen, Jussi Sutinen
In recent years, the concept of quality of life (QoL) has received significant attention in the HIV/AIDS literature. In Finland, however, the factors associated with the QoL of people living with HIV/AIDS (PLWHA) still remain unknown. The aim of this study was to identify the sociodemographic and HIV-related factors associated with the different domains of QoL of PLWHA in Finland. The sample of this cross-sectional study consisted of 453 HIV-infected patients (Mean age = 46.5 years; 76.5% male) followed at the Infectious Disease Clinic of Helsinki University Hospital...
January 23, 2017: AIDS Care
https://www.readbyqxmd.com/read/28110546/social-cultural-factors-of-hiv-related-stigma-among-the-chinese-general-population-in-hong-kong
#18
Tien Ee Dominic Yeo, Tsz Hang Chu
HIV-related stigma in the wider community compounds the suffering of people living with HIV (PLWH) and hampers effective HIV prevention and care. This study examines the level of public stigma toward PLWH in Hong Kong and associated social-cultural factors. A telephone survey was conducted in June-July 2016 with 1080 Chinese adults aged 18-94 randomly selected from the general population. The results indicate substantial degree of public stigma toward PLWH. Overall, 58.1% of the participants endorsed at least one statement indicating negative social judgment of PLWH...
January 23, 2017: AIDS Care
https://www.readbyqxmd.com/read/28107805/effectiveness-of-an-sms-based-maternal-mhealth-intervention-to-improve-clinical-outcomes-of-hiv-positive-pregnant-women
#19
Jesse Coleman, Kate C Bohlin, Anna Thorson, Vivian Black, Patricia Mechael, Josie Mangxaba, Jaran Eriksen
We conducted a retrospective study to investigate the effectiveness of an mHealth messaging intervention aiming to improve maternal health and HIV outcomes. Maternal health SMSs were sent to 235 HIV-infected pregnant women twice per week in pregnancy and continued until the infant's first birthday. The messages were timed to the stage of the pregnancy/infant age and covered maternal health and HIV-support information. Outcomes, measured as antenatal care (ANC) visits, birth outcomes and infant HIV testing, were compared to a control group of 586 HIV-infected pregnant women who received no SMS intervention...
January 20, 2017: AIDS Care
https://www.readbyqxmd.com/read/28107796/social-and-structural-factors-related-to-hiv-risk-among-truck-drivers-passing-through-the-iringa-region-of-tanzania
#20
Anjalee Kohli, Deanna Kerrigan, Heena Brahmbhatt, Samuel Likindikoki, Justin Beckham, Ard Mwampashi, Jessie Mbwambo, Caitlin E Kennedy
Truck drivers and their assistants have been identified as groups at higher risk for HIV infection. We sought to identify and describe the social and structural factors that may contribute to HIV risk among truck drivers who visit rest stops in Iringa, Tanzania, a region characterized by high levels of migration and mobility. This analysis was part of a comprehensive strategic assessment to examine HIV risk factors in Iringa. This analysis focuses on 11 in-depth interviews with truck drivers and a transport owner...
January 20, 2017: AIDS Care
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