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Janet Njelesani, Donald Njelesani
There has been a proliferation of organizations in Zambia touting the mobilization of traditional games as a tool to prevent HIV. However, there is a dearth of evidence on how culturally important activities like traditional games are being incorporated into programing. The purpose of this study was to explore how traditional games are used as a strategy to prevent HIV in Zambia. This qualitative study generated data from 17 case studies of HIV programs operating in Lusaka, Zambia. Observations of the programs were conducted and 44 interviews with program staff were completed...
May 18, 2018: AIDS Care
Ruth C Angrand, Rhoda Sperling, Kinga Roccobono, Lauren M Osborne, Jennifer Jao
"Depression (as noted in chart by a physician)" was compared between HIV infected pregnant women and controls. Perinatally HIV-infected (PHIV), non-perinatally HIV-infected (NPHIV), and HIV-uninfected (HIV-U) pregnant women were all compared using a logistic regression model. Overall, HIV-infected women had higher rates of depression than HIV-U, with PHIV women demonstrating a clinically and statistically significant increased risk compared to HIV-U women [adjusted OR: 15.9, 95% CI = 1.8-143.8]...
May 18, 2018: AIDS Care
Frida Hjalte, Paul S Calara, Anders Blaxhult, Marie Helleberg, Karoline Wallace, Peter Lindgren
People living with HIV have an increased risk of comorbidities with non-communicable diseases such as cardiovascular disease, chronic kidney disease and osteoporotic fractures, compared to the general population. The burden of these comorbidities is expected to rise as the HIV-infected population ages. This development may require additional health care resources and it is relevant to ascertain the costs associated with these comorbidities. The population attributed risk approach was applied to estimate excess costs associated with the higher rates of comorbidities among HIV patients in Denmark and Sweden compared to their respective general populations...
May 18, 2018: AIDS Care
Sarah E Van Pilsum Rasmussen, Macey L Henderson, Juli Bollinger, Shanti Seaman, Diane Brown, Christine M Durand, Dorry L Segev, Jeremy Sugarman
Recent changes to United States law now permit people living with HIV (PLWH) to donate organs to HIV-infected (HIV+) recipients under research protocols. PLWH may have unique motivations for and concerns about living donation and understanding them is critical to ensuring the integrity of this novel approach to organ transplantation. We conducted in-depth interviews with PLWH from an urban HIV clinic who had previously indicated their willingness to be a living donor. Interviews elicited information on their motivations, perceived benefits, and concerns regarding living donation...
May 3, 2018: AIDS Care
Kim Engler, Andras Lènàrt, David Lessard, Isabelle Toupin, Bertrand Lebouché
Suboptimal adherence to antiretroviral therapy (ART) remains common. Patient-centered tools are needed to comprehensively assess adherence barriers in HIV clinical practice. Thus, we conducted a research synthesis to produce a conceptual framework for a new patient-reported outcome measure (PRO) for use in routine HIV care in Canada and France. A PRO's conceptual framework graphically represents the concepts to be measured and the potential relationships between them. Towards ensuring the framework's relevance to the target populations' concerns, qualitative studies with HIV-positive adults on barriers to ART adherence in developed countries were synthesized with thematic analysis, attending to the cross-study prevalence and interrelationships of barrier themes...
May 2, 2018: AIDS Care
Taylor McLinden, Erica E M Moodie, Sam Harper, Anne-Marie Hamelin, Aranka Anema, Wusiman Aibibula, Marina B Klein, Joseph Cox
Injection drug use (IDU) and food insecurity (FI) are highly prevalent among individuals living with HIV-hepatitis C virus (HCV) co-infection. We quantified the association between IDU and FI among co-infected individuals using biannual data from the Canadian Co-infection Cohort (N = 608, 2012-2015). IDU (in the past six months) and IDU frequency (non-weekly/weekly in the past month) were self-reported. FI (in the past six months) and FI severity (marginal FI, moderate FI, and severe FI) were measured using the Household Food Security Survey Module...
May 1, 2018: AIDS Care
Eusébio Chaquisse, Paula Meireles, Sílvia Fraga, Francisco Mbofana, Henrique Barros
The assessment of pregnant women's knowledge about modes of infections transmission is essential to tailor programs to their needs. This study aimed to assess knowledge about human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) among pregnant women in Nampula - Mozambique, a high-risk area for sexually transmitted infections. At their first antenatal visit, women were invited to participate and data were collected by trained nurses at six public health facilities. Knowledge about HIV transmission modes was high but relevant misconceptions remained...
April 27, 2018: AIDS Care
Brian Houle, Sanyu A Mojola, Nicole Angotti, Enid Schatz, F Xavier Gómez-Olivé, Samuel J Clark, Jill R Williams, Chodziwadziwa Kabudula, Stephen Tollman, Jane Menken
There is limited information about sexual behavior among older Africans, which is problematic given high HIV rates among older adults. We use a population-based survey among people aged 15-80+ to examine the prevalence of sexual risk and protective behaviors in the context of a severe HIV epidemic. We focus on variation across the life course, gender and HIV serostatus to compare the similarities and differences of young, middle aged, and older adults. Younger adults continue to be at risk of HIV, with potential partners being more likely to have been diagnosed with an STI and more likely to have HIV, partner change is high, and condom use is low...
April 27, 2018: AIDS Care
Eaden Andu, Brad H Wagenaar, Chris G Kemp, Paul E Nevin, Jane M Simoni, Michele Andrasik, Susan E Cohn, Audrey L French, Deepa Rao
We sought to examine risk and protective factors for Posttraumatic Stress Disorder (PTSD) among African American women living with HIV. This is a cross-sectional analysis of baseline data from a randomized trial of an HIV stigma reduction intervention. We examined data from two-hundred and thirty-nine African American women living with HIV. We examined whether age, marital status, level of education, internalized HIV-related stigma, and social support as potential protective and risk factors for PTSD symptoms using logistic regression...
April 26, 2018: AIDS Care
Yuan-Yuan Wang, Jin Zhao, Qinge Zhang, Yan Zhang, Baolian Bai, Chee H Ng, Gabor S Ungvari, Fu-Jun Jia, Yu-Tao Xiang
To investigate the prevalence of depressive syndrome and their association with demographic and clinical characteristics in Chinese patients infected with the human immunodeficiency virus (HIV). A total of 416 patients with HIV infection were consecutively screened and enrolled in the study. Depressive syndrome was assessed with the Center for Epidemiologic Studies-Depression Scale (CES-D). The proportion of depressive syndrome was 36.3%. Patients with depressive syndrome were younger, and were more likely to have severe anxiety symptoms, religious beliefs and psychological treatment...
April 24, 2018: AIDS Care
Lauren R Pacek, F Joseph McClernon, Olga Rass, Maggie M Sweizter, Matthew W Johnson
Perceived risk of smoking is associated with smoking status, interest in quitting, cessation attempts, and quit success. Research is needed to explore risk perceptions of developing smoking-related disease among persons living with HIV (PLWH). Data came from 267 HIV-positive smokers who completed an online survey assessing perceived health risks associated with (a) generic smoking status; (b) generic non-smoking status; (c) their own personal current smoking; and (d) a hypothetical situation in which they were a non-smoker...
April 22, 2018: AIDS Care
Tiara C Willie, Trace S Kershaw, Tamora A Callands
Gender inequities place women at an increased risk for HIV acquisition, and this association may particularly disenfranchize young pregnant women. Intimate partner violence (IPV) and food insecurity may contribute to gender differences in power, thereby influencing HIV disparities between women and men. Factors influencing gender disparities in HIV are unique and country-specific within sub-Saharan Africa, yet these factors are understudied among women in Liberia. This paper sought to examine the unique contributions and intersections of intimate partner violence (IPV) and food insecurity with HIV-related risk factors among young pregnant women in Liberia...
April 22, 2018: AIDS Care
Nicole J Phillips, Jacqueline Hoare, Dan J Stein, Landon Myer, Heather J Zar, Kevin G F Thomas
Accurate assessment of HIV-associated cognitive disorders in perinatally infected children and adolescents is challenging. Assessments of general intellectual functioning, or global cognition, may not provide information regarding domain-specific strengths and weaknesses, and may therefore fail to detect, impaired trajectories of development within particular cognitive domains. We compare the efficacy of global cognitive scores to that of composite cognitive domain scores in detecting cognitive disorders in a sample of perinatally HIV-infected children, and a demographically matched HIV negative control group, drawn from the Cape Town Adolescent Antiretroviral Cohort (CTAAC) study...
April 22, 2018: AIDS Care
Peter F Rebeiro, Chanelle J Howe, William B Rogers, Sally S Bebawy, Megan Turner, Asghar Kheshti, Catherine C McGowan, Stephen P Raffanti, Timothy R Sterling
Retention in care and viral suppression are critical to delaying HIV progression and reducing transmission. Neighborhood socioeconomic context (NSEC) may affect HIV care receipt. We therefore assessed NSEC's impact on retention and viral suppression in a diverse HIV clinical cohort. HIV-positive adults with ≥1 visit at the Vanderbilt Comprehensive Care Clinic and 5-digit ZIP code tabulation area (ZCTA) information between 2008 and 2012 contributed. NSEC z-score indices used neighborhood-level socioeconomic indicators for poverty, education, labor-force participation, proportion of males, median age, and proportion of residents of black race by ZCTA...
April 20, 2018: AIDS Care
Oluwatosin Olaiya, Lina Nerlander, Christine L Mattson, Linda Beer
Many studies of persons who exchange sex for money or drugs have focused on their HIV acquisition risk, and are often limited to select populations and/or geographical locations. National estimates of exchange sex among people living with HIV (PLWH) who are in medical care, and its correlates, are lacking. To address these gaps, we analyzed data from the Medical Monitoring Project, a surveillance system that produces nationally representative estimates of behavioral and clinical characteristics of PLWH receiving medical care in the United States, to estimate the weighted prevalence of exchange sex overall, and by selected socio-demographic, behavioral and clinical characteristics...
April 20, 2018: AIDS Care
Alfred A Larbi, Freya Spielberg, Nnemdi Kamanu Elias, Erin Athey, Ngozi Ogbuawa, Nancy Murphy
People living with HIV can experience the full benefits of retention when they are continuously engaged in care. Continuous engagement in care promotes improved adherence to ART and positive health outcomes. An infectious disease clinic has implemented a protocol to primarily improve patient retention. The retrospective, facility-based, costing study took place in an infectious disease clinic in Washington DC. Retention was defined in two ways and over a 12-month period. Micro-costing direct measurement methods were used to collect unit costs in time series...
April 18, 2018: AIDS Care
Geoffrey Jobson, Andrew Tucker, Glenn de Swardt, Kevin Rebe, Helen Struthers, James McIntyre, Remco Peters
Gender identity plays a potentially important role contributing to HIV risk among MSM in South Africa. Where studies have included a focus on gender identity, MSM reporting gender non-conformity have been found to have a higher risk of being HIV positive than other MSM. This article examines HIV risk among gender non-conforming MSM in a sample of 316 MSM in Cape Town, South Africa. Reporting gender non-conformity was associated with higher HIV prevalence and increased HIV risk behaviour. Gender non-conformity was also associated with a higher likelihood of being unemployed and reporting low household incomes...
April 18, 2018: AIDS Care
Keira Lowther, Richard Harding, Victoria Simms, Nancy Gikaara, Aabid Ahmed, Zipporah Ali, Hellen Kariuki, Lorraine Sherr, Irene J Higginson, Lucy Selman
We conducted in Kenya a mixed-methods randomised controlled trial (RCT) of a nurse-led palliative care intervention integrated with anti-retroviral therapy (ART) provision for the management of HIV. Here we report qualitative findings showing increased resistance to HIV-associated stigma among trial participants. A mixed method design was chosen to enable identification of the active ingredients of the intervention and exploration of participants' experiences of receiving the intervention. The RCT was conducted from July 2011 to November 2012 in a community hospital in the city of Mombasa, Kenya, with a sample of 120 adults with HIV on ART...
April 17, 2018: AIDS Care
Jefferson Traebert, Eliane Traebert, Fabiana Schuelter-Trevisol, Juan Jose Cortez Escalante, Ione Jayce Ceola Schneider
Although traditional epidemiological information, such as mortality rate and prevalence or incidence rates, is relevant to the understanding of AIDS epidemiology in Brazil, a more complete indicator would be recommended. The aim of this study was to estimate the burden of AIDS and its trends in Brazil from 1980 to 2015. An ecological study using secondary data on mortality, morbidity and demography was carried out. Data were collected from official health information sources. Disability-adjusted life years (DALY) index was estimated by year...
April 6, 2018: AIDS Care
Wang Xiaowen, Guo Guangping, Zhou Ling, Zheng Jiarui, Liang Xiumin, Li Zhaoqin, Luo Hongzhuan, Yang Yuyan, Yang Liyuan, Lu Lin
Pregnant women living with HIV represent one of the most high-priority groups for HIV treatment and health assessment. Although social support has been shown to be a protective factor for improved health-related quality of life (HRQoL), and depression and anxiety have been identified as two major causes of psychological distress among people living with HIV, it is still unclear how social support, anxiety, and depression interact to influence HRQoL. The objective of our study was to demonstrate the nature of predictors, direct effects and mediator effects among social support, anxiety, depression symptoms and HRQoL in pregnant women living with HIV...
April 1, 2018: AIDS Care
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