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Indian Journal of Nephrology

H S Mahapatra, L Pursnani, H Verma, M Bhardwaj
No abstract text is available yet for this article.
May 2018: Indian Journal of Nephrology
S Nayak, M Sharma, A Kataria, S C Tiwari, A Rastogi, A Mukund
No abstract text is available yet for this article.
May 2018: Indian Journal of Nephrology
M C Abdulla, S Sathyan, Z Shemin, N Mampilly
No abstract text is available yet for this article.
May 2018: Indian Journal of Nephrology
S Sandal, K Tiewsoh, N Hansdak, B Parajuli
No abstract text is available yet for this article.
May 2018: Indian Journal of Nephrology
H Vora, B Kulkarni, S Singh, N Kulkarni
Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis in a patient of scleroderma is very rare. Very few cases have been reported in English literature. We report a case of a 58-year-old male with long-standing limited cutaneous scleroderma (Scl-70 positive) presenting with normotensive scleroderma renal crisis. Perinuclear ANCA with antimyeloperoxidase antibody was found to be strongly positive. Renal biopsy showed pauci immune-necrotizing crescentic glomerulonephritis. We believe that this case report will be helpful in understanding clinical features of normotensive ANCA-associated glomerulonephritis in scleroderma patients...
May 2018: Indian Journal of Nephrology
S V Vyahalkar, N M Dedhia, M M Bahadur, G S Sheth, V K Joglekar, V M Sawardekar, S S Khan, S M Shaikh
Hyperoxaluria and resultant oxalate nephropathy are infrequently reported causes of irreversible renal failure. A rapid decline in renal function in an otherwise insidiously progressive oxalate nephropathy may be triggered by various superimposed insults like the use of nephrotoxic drugs. We present the case of a patient with rapidly progressive renal failure due to oxalate nephropathy that lead to a retrospective diagnosis of chronic pancreatitis. This case highlights the importance of timely assessment for enteric hyperoxaluria in patients with unexplained renal failure of tubulointerstitial nature...
May 2018: Indian Journal of Nephrology
D N Gera, J Patel, K Patel, V B Kute
Deep vein thrombosis, renal vein thrombosis, and cerebral venous sinus thrombosis in children are frequently described complications of nephrotic syndrome (NS). Early diagnosis and treatment with anticoagulants is the key for a good outcome. There are a few reported cases of portal vein and superior mesenteric thrombosis in adults in association with NS. Here, we describe two cases of portal vein thrombosis with variable extent of involvement of superior mesenteric vein in association with relapse of NS. A high degree of suspicion, ultrasonography of the abdomen along with Doppler study of abdominal vessels, and computed tomography angiography can only pick up such unusual sites of thrombosis and facilitate early management...
May 2018: Indian Journal of Nephrology
N Prasad, R Manjunath, D Bhadauria, R S K Marak, R K Sharma, V Agarwal, M Jain, A Gupta
Invasive fungal infection is a complication seen in immunocompromised patients. A disseminated fungal infection has a high rate of mortality. Although disseminated infection is known to be seen in most organs, thyroid involvement is rarely reported. Hence, we report a fatal case of thyroid mucormycosis which resulted into laryngeal nerve paralysis and death of a renal allograft recipient.
May 2018: Indian Journal of Nephrology
R Goli, Sree Bhushan Raju, M S Uppin
Monoclonal gammopathy of renal significance (MGRS) can present with myriad of morphological features. We report a case of MGRS in a 46-year-old man who presented with nephrotic-range proteinuria and renal insufficiency. Renal biopsy showed amorphous eosinophilic periodic acid-Schiff positive deposits in capillary loops and lamda light chain positivity on immunofluorescence, suggestive of cyoglobulinemic glomerulonephritis. Serum cryoglobulins were positive. Serum immunoelectrophoresis and immunofixation showed a M band of 0...
May 2018: Indian Journal of Nephrology
G Anvesh, S B Raju, K Prasad, A Sharma, M Surendra
Waardenburg syndrome (WS) is a rare genetic disorder characterized by varying degrees of hearing loss, pigmentary anomalies, and defects of other neural crest cell-derived structures. The association of WS with renal anomalies has been described in the literature. However, nephrotic syndrome is a very rare association with WS, and only one case has been reported in the literature. We report a case of WS2 associated with biopsy-proven nephrotic syndrome (minimal change disease).
May 2018: Indian Journal of Nephrology
N Prasad, M R Patel, A Pandey, A Jaiswal, D Bhadauria, A Kaul, R K Sharma, S Mohindra, G Pandey, A Goel, A Gupta
Hepatitis C virus (HCV) infection in renal allograft recipient is associated with increased morbidity and mortality. At present, only few studies related to treatment and outcomes of HCV-infected renal allograft recipients with DAAs have been published. We aimed the study to assess the efficacy and safety of sofosbuvir-based regimens in HCV-infected renal allograft recipients. We analyzed data of 22 eligible HCV-infected renal allograft recipients (14 genotype-3, 6 genotype-1, one each genotype-2 and 4) who were treated with DAAs at our institute...
May 2018: Indian Journal of Nephrology
M Trivedi, A Pasari, A R Chowdhury, A Abraham-Kurien, R Pandey
Focal segmental glomerulosclerosis (FSGS) is a disease that is defined entirely by its histopathological appearance. The recent Columbian classification has grouped this disease into various types based on the light microscopic description. There is a paucity of data describing the distribution of its various subtypes from the Indian subcontinent. This study was undertaken with the aim to throw light on the epidemiology and clinical features of primary FSGS in Eastern India. This retrospective study includes our cohort of biopsy-proven FSGS who presented to us from June 2009 to July 2011 and the analysis of their presenting clinical and histopathological features from our center in East India...
May 2018: Indian Journal of Nephrology
N Singh, R Nada, A Rawat, A Sharma, S K Sinha, R Ramachandran, V Kumar, H S Kohli, K L Gupta, M Rathi
IgG4-related kidney disease (IgG4 RKD) is increasingly reported with varied manifestations. The present study was carried out to study the spectrum of IgG4 RKD. All patients with renal manifestation associated with conditions known to be associated with IgG4-related diseases (IgG4 RDs), or renal imaging or histology suggestive of IgG4 RKD were included and evaluated further. Patients with known extrarenal IgG4RD were also screened for renal involvement. Out of 40 patients screened over a period of 15 months, IgG4 RKD was diagnosed in 8...
May 2018: Indian Journal of Nephrology
M Mantan, R Grover, S Kaushik, S Yadav
Corticosteroids form the mainstay of therapy for all forms of nephrotic syndrome. The long-term use of this medication is associated with serious side effects including adrenocortical suppression. The primary objective of this study was to identify adrenocortical suppression (assessed by single morning serum cortisol levels) in children with nephrotic syndrome on treatment with low-dose alternate day steroids. This cross-sectional study was conducted in the Department of Pediatrics in a tertiary care hospital from January 2014 to January 2015...
May 2018: Indian Journal of Nephrology
P J Koshy, R Parthsarathy, M Mathew, R Prabakaran, S Kuruvilla, G Abraham
The adult population above the age of 60 years has significantly increased in India, with a life expectancy of 68.4 years in 2016. Data regarding the renal histopathology in these patients are scarce though the number of native kidney biopsies done in this subset of population is increasing. The present study is a retrospective analysis of 231 biopsies from a total of 700 biopsies, from patients above 60 years of age (M = 65.8%; F = 34.2%) with a mean age of 64 ± 6.03 years. The indications for kidney biopsy included nephrotic syndrome (NS) (30...
May 2018: Indian Journal of Nephrology
S Derakhshan, M Pourzare, D Roshani
Escherichia coli is the major causative pathogen of urinary tract infection (UTI) in humans. Virulence and drug resistance play important roles in the pathogenesis of E. coli infections. The aims were to investigate the presence of uropathogenic virulence genes and to evaluate a relationship between antibiotic resistance and virulence in E. coli from UTI. A total of 132 E. coli were collected between April and June 2015 in two hospitals of Sanandaj, Iran. Isolates were examined for susceptibility to 16 antibiotic disks using the disk diffusion method and for possession of virulence genes by polymerase chain reaction...
May 2018: Indian Journal of Nephrology
Y Naresh, N Srinivas, Kiranmayi S Vinapamula, P Pullaiah, P V L N Srinivasa Rao, V Sivakumar
Carbamylated hemoglobin (CarHb) was found to have a potential role in the differentiation of patients with acute kidney injury (AKI) from chronic kidney disease (CKD). This study was aimed at the evaluation of the diagnostic performance and usefulness of CarHb in the differentiation of AKI from CKD. Forty patients with renal disease and twenty age- and sex-matched healthy controls were included in the study. Urea, creatinine, Hb, and CarHb were measured in all the subjects. Patients with AKI and CKD were found to have significantly increased levels of CarHb when compared to controls ( P < 0...
May 2018: Indian Journal of Nephrology
T J Vachharajani
No abstract text is available yet for this article.
May 2018: Indian Journal of Nephrology
Y K Wen
No abstract text is available yet for this article.
March 2018: Indian Journal of Nephrology
G Li Cavoli, O Schillaci, C Zagarrigo, F Servillo, T V Li Cavoli, M Palmeri, U Rotolo
No abstract text is available yet for this article.
March 2018: Indian Journal of Nephrology
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