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Indian Journal of Nephrology

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https://www.readbyqxmd.com/read/27795642/incidence-of-diabetes-and-hypertension-in-indigenous-amerindian-village-in-guyana-south-america
#1
R M Jindal, R Soni, K Mehta, T G Patel
No abstract text is available yet for this article.
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795641/outreach-activities-for-kidney-diseases-in-children
#2
U Ali, P Shanbag
No abstract text is available yet for this article.
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795640/large-hemorrhagic-ovarian-cyst-in-postmenopausal-patient-with-autosomal-dominant-polycystic-kidney-disease
#3
V V Mishra, S Nanda, R Agarwal, R Aggarwal
No abstract text is available yet for this article.
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795639/mega-fistula
#4
B Sangeetha, V Chaitanya, M H Reddy, A C V Kumar, R Ram, V Sivakumar
No abstract text is available yet for this article.
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795638/bilateral-nephrocalcinosis-in-primary-hyperoxaluria-type-1
#5
C A Mansoor, A Jemshad, D S Milliner, N K N Bhushan
No abstract text is available yet for this article.
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795637/septicemic-melioidosis-in-a-transplant-recipient-causing-graft-dysfunction
#6
S Sathiavageesan
Melioidosis, an infectious disease caused by Burkholderia pseudomallei, is endemic in the Northern Australia and South-East Asia. It is an emerging disease in the Indian subcontinent. Melioidosis tends to run a potentially lethal course in immunocompromised individuals and data in renal transplantation are scarce. The clinical presentation of melioidosis is diverse, mimicking several other infectious diseases. Diagnosis could be delayed in transplant recipients. Choice and duration of antimicrobial therapy, management of immunosuppression, and patient and graft outcomes are other issues to be addressed...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795636/two-consecutive-recurrences-of-crescentic-immunoglobulin-a-nephropathy-in-a-renal-transplant-recipient
#7
N Gopalakrishnan, S Murugananth, T Dineshkumar, J Dhanapriya, R Sakthirajan, T Balasubramaniyan
We report a 21-year-old male who developed end-stage renal disease, probably due to immunoglobulin A nephropathy (IgAN), received a renal transplant from his mother, which was lost due to crescentic IgAN after 18 months. Two years later, he received a second transplant from a deceased donor. He developed rapidly progressive graft dysfunction 3 years later. Allograft biopsy revealed crescentic IgAN, which was successfully treated with intravenous steroids and cyclophosphamide. Recurrence of IgAN in two successive allografts in one patient has not been reported previously...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795635/collapsing-glomerulopathy-associated-with-pulmonary-tuberculosis
#8
N D Srinivasaprasad, G Chandramohan, V Praveen, M E Fernando
Collapsing glomerulopathy (CG) usually presents with reduced glomerular filtration rate, heavy proteinuria and has unfavorable prognosis. Numerous associations with CG are found. We encountered a case of CG associated with pulmonary tuberculosis presenting with proteinuria and dialysis-requiring severe renal failure. Our patient made partial recovery of his renal function and became dialysis-independent after antituberculous therapy and oral steroids. Long-term follow-up is needed to assess the progression of the disease...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795634/complete-remission-of-nephrotic-syndrome-and-acute-kidney-injury-in-crescentic-iga-nephropathy-role-of-mycophenolate-sodium
#9
D Bhandari, K D Jhaveri, H H Shah
Optimal therapy and prognosis of crescentic-IgA nephropathy (C-IgAN) are not known. Reported treatment options for C-IgAN include combination of corticosteroids and cyclophosphamide for 6 months. The role of mycophenolate sodium in C-IgAN is unknown. We report a case of C-IgAN that was successfully treated with combination immunosuppressive therapy.
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795633/renal-infarct-following-varicella-infection
#10
D Arora, A Jairam, D Mahapatra
Renal infarction usually occurs against a background of heart disease or a thromboembolic tendency and rarely is associated with infections. Here we present a case of a young boy who reported with painless gross hematuria following primary Varicella infection and was found to have an isolated renal infarct.
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795632/a-novel-heterozygous-missense-mutation-in-uromodulin-gene-in-an-indian-family-with-familial-juvenile-hyperuricemic-nephropathy
#11
D Saxena, P Srivastava, S R Phadke
Familial juvenile hyperuricemic nephropathy (FJHN), characterized by early-onset hyperuricemia, reduced fractional excretion of uric acid, and chronic renal failure is caused due to mutation in uromodulin (UMOD) gene. We identified a novel mutation in a family with multiple members affected with FJHN. Ten coding exons of UMOD gene in three family members with clinical and biochemical features of FJHN and one unaffected family member were sequenced, and sequence variants were analyzed for the pathogenicity by bioinformatics studies...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795631/clinicopathological-correlates-of-chronic-kidney-disease-of-unknown-etiology-in-sri-lanka
#12
M Selvarajah, P Weeratunga, S Sivayoganthan, N Rathnatunga, S Rajapakse
Chronic kidney disease of unknown etiology (CKDu) is a major healthcare issue in Sri Lanka. This study included 125 consecutive patients with a diagnosis of CKDu undergoing renal biopsy at one hospital from 2008 to 2012. Associations between renal outcome parameters, epidemiological data, and histopathological findings were examined and regression models constructed based on univariate associations with outcome variables as serum creatinine >1.2 and stage of CKD >3. The mean patient age was 46.21 years (standard deviation = 11...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795630/high-hemodialysis-vascular-access-flow-and-impaired-right-ventricular-function-in-chronic-hemodialysis-patients
#13
S Yilmaz, M Yetim, B K Yilmaz, T Dogan, E Aksoy, N Yuksel, I Dogan
There are limited data showing right ventricular preload increase due to high-flow arteriovenous fistulas (AVFs). This cross-sectional study investigated whether high AVF flow had an impact on right ventricular function in patients undergoing hemodialysis. Sixty-four patients aged between 18 and 85 years who were on routine hemodialysis with >2 hemodialysis sessions per week for at least 3 months via an AVF were studied. Patients with inadequate flow fistulas, severe chronic obstructive pulmonary disease, history of pulmonary embolism, primary pulmonary hypertension, severe mitral, aortic or pulmonary regurgitation, and/or stenosis were excluded...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795629/clinicopathological-correlation-and-treatment-response-of-primary-focal-segmental-glomerulosclerosis-in-adults-and-adolescents
#14
J Dhanapriya, T Dineshkumar, N Gopalakrishnan, R Sakthirajan, T Balasubramaniyan
The incidence of focal segmental glomerulosclerosis (FSGS) is approximately 10% in children <6 years, 20% in adolescents, and 20-25% in adults. A retrospective observational study was done to document clinicopathological correlation, treatment response, and risk factors in the progression of chronic kidney disease (CKD) of primary FSGS in adults and adolescents. A total of 170 patients were studied with a mean follow-up of 4.32 ± 1.2 years. FSGS not otherwise specified was the most common subtype (56%) followed by tip variant (24%)...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795628/swan-neck-versus-straight-peritoneal-dialysis-catheter-long-term-effect-on-patient-and-method-survival
#15
V Filiopoulos, D Biblaki, L Takouli, A Dounavis, D Hadjiyannakos, D Vlassopoulos
Peritoneal dialysis (PD) is limited mainly by a higher technique failure rate as compared to hemodialysis (HD), catheter malfunction being an important reason. Intra- and extra-peritoneal catheter configuration may be associated with mechanical and infectious complications affecting method survival. We report our experience with two extra-peritoneal catheter configurations: the straight and the swan-neck (SN) catheters. A total of 85 consecutive patients, 58 males and 27 females were included in the study. Among them, 26 were diabetics; 52 were treated with automated PD (APD) and 33 with continuous ambulatory PD (CAPD)...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795627/hemodialysis-among-pregnancy-related-acute-kidney-injury-patients-a-single-center-experience-in-north-western-nigeria
#16
A M Makusidi, H M Liman, A Yakubu, M Hassan, M D Isah, A Chijioke
Pregnancy related acute kidney injury (PRAKI) patients that underwent hemodialysis (HD) between May 2007 and April 2015 were studied with specific reference to clinical features, laboratory values, duration of pregnancy at the diagnosis of acute kidney injury and outcome. It involved 38 patients aged between 15 and 30 years. The main clinical features were fever, edema and oliguria. The leading etiological factors included ante/postpartum hemorrhage, septic abortion, and toxemia of pregnancy. The majority of cases occurred during the third trimester...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795626/anti-glomerular-basement-membrane-crescentic-glomerulonephritis-a-report-from-india-and-review-of-literature
#17
A Gupta, V Agrawal, A Kaul, R Verma, R Pandey
Anti-glomerular basement membrane (anti-GBM) disease is an autoimmune disease that most commonly presents as rapidly progressive glomerulonephritis with or without pulmonary involvement. It is characterized by the presence of antibodies directed to antigenic targets within glomerular and alveolar basement membranes. This study was performed to evaluate the clinicopathological features and outcome in anti-GBM crescentic glomerulonephritis (CrGN) at a tertiary care center in North India over a period of 9 years (January 2004 to December 2012)...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795625/a-prospective-audit-of-complications-in-100-consecutive-pediatric-percutaneous-renal-biopsies-done-under-real-time-ultrasound-guidance
#18
R Sinha, B Maji, B Sarkar, S Meur
Despite being a common procedure, percutaneous renal biopsy (PRB) carries the potential for complications. The British Association of Paediatric Nephrologist (BAPN) has published standards for pediatric PRB. As Indian data are scarce, we conducted a prospective audit of 100 consecutive pediatric renal biopsies (60% males) under real-time ultrasound guidance. Nephrotic syndrome was the most common indication for PRB (68%) with minimal change disease (30%) and focal segmental glomerulosclerosis (25%) being the most common histopathological lesions...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795624/rifampicin-and-anti-hypertensive-drugs-in-chronic-kidney-disease-pharmacokinetic-interactions-and-their-clinical-impact
#19
A Agrawal, S K Agarwal, T Kaleekal, Y K Gupta
Patients on dialysis have an increased incidence of tuberculosis (TB). Rifampicin, a first-line antitubercular therapy (ATT) drug, is a potent inducer of hepatic cytochrome P450 (CYP). There is potential for pharmacokinetic interaction between rifampicin and anti-hypertensives that are CYP substrates: amlodipine and metoprolol. Therefore, hypertensive patients receiving rifampicin-based ATT are at risk for worsening of hypertension. However, this hypothesis has not yet been systematically studied. In this prospective study, hypertensive CKD 5D patients with TB were followed after rifampicin initiation...
September 2016: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/27795623/rituximab-in-the-treatment-of-refractory-late-acute-antibody-mediated-rejection-our-initial-experience
#20
M Surendra, S B Raju, N Raju, S Chandragiri, K K Mukku, M S Uppin
Antibody-mediated rejection (AMR) is not uncommon after renal transplantation and is harder to handle compared to cell-mediated rejection. When refractory to conventional therapies, rituximab is an attractive option. This study aims to examine the effectiveness of rituximab in refractory late acute AMR. This is a retrospective study involving nine renal transplant recipients. Four doses of rituximab were administered at weekly interval for 4 weeks, at a dose of 375 mg/m(2). The mean age of patients was 35.3 ± 7...
September 2016: Indian Journal of Nephrology
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