journal
MENU ▼
Read by QxMD icon Read
search

Critical Reviews in Microbiology

journal
https://www.readbyqxmd.com/read/28071145/bacteriophages-and-their-derivatives-for-the-treatment-and-control-of-food-producing-animal-infections
#1
Carla Carvalho, Ana Rita Costa, Filipe Silva, Ana Oliveira
Nowadays, the world is facing an increasing emergence of antibiotic resistant bacteria. Simultaneously, the banning of some existing antibiotics and the lack of development of new antimicrobials have created an urgent need to find new alternatives against animal infections. Bacteriophages (phages) are naturally occurring predators of bacteria, ubiquitous in the environment, with high host specificity and harmless to animals. For these reasons, phages and their derivatives are being considered valuable antimicrobial alternatives and an opportunity to reduce the current use of antibiotics in agri-food production, increasing animal productivity and providing environmental protection...
January 10, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28068855/iron-oxide-nanoparticles-in-modern-microbiology-and-biotechnology
#2
Ranmadugala Dinali, Alireza Ebrahiminezhad, Merilyn Manley-Harris, Younes Ghasemi, Aydin Berenjian
Iron oxide nanoparticles (IONs) are one of the most developed and used nanomaterials in biotechnology and microbiology. These particles have unique physicochemical properties, which make them unique among nanomaterials. Therefore, many experiments have been conducted to develop facile synthesis methods for these particles and to make them biocompatible. Various effects of IONs on microorganisms have been reported. Depending on the microbial strain and nanoparticle (NP) concentration, IONs can stimulate or inhibit microbial growth...
January 10, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28068853/chronic-lung-disease-in-common-variable-immune-deficiency-cvid-a-pathophysiological-role-for-microbial-and-non-b-cell-immune-factors
#3
Denver Mooney, David Edgar, Gisli Einarsson, Damian Downey, Stuart Elborn, Michael Tunney
One of the most common and most severe forms of primary antibody deficiency encountered in the clinical setting is a heterogeneous group of syndromes termed common variable immune deficiency (CVID). This disorder is characterized by reduced immunoglobulin production and increased susceptibility to infection, particularly of the respiratory tract. Infection and subsequent immunological/inflammatory processes may contribute to the development of pulmonary complications such as bronchiectasis and interstitial lung disease...
January 10, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28033847/impact-of-polymicrobial-biofilms-in-catheter-associated-urinary-tract-infections
#4
Andreia S Azevedo, Carina Almeida, Luís F Melo, Nuno F Azevedo
Recent reports have demonstrated that most biofilms involved in catheter-associated urinary tract infections are polymicrobial communities, with pathogenic microorganisms (e.g. Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae) and uncommon microorganisms (e.g. Delftia tsuruhatensis, Achromobacter xylosoxidans) frequently co-inhabiting the same urinary catheter. However, little is known about the interactions that occur between different microorganisms and how they impact biofilm formation and infection outcome...
December 30, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28033730/the-proteasome-of-the-differently-diverged-eukaryote-giardia-lamblia-and-its-role-in-remodeling-of-the-microtubule-based-cytoskeleton
#5
Atrayee Ray, Srimonti Sarkar
Giardia lamblia is the causative agent of the diarrheal disease giardiasis, against which only a limited number of drugs are currently available. Increasing reports of resistance to these drugs makes it necessary to identify new cellular targets for designing the next generation of anti-giardial drugs. Towards this goal, therapeutic agents that target the parasitic cellular machinery involved in the functioning of the unique microtubule-based cytoskeleton of the Giardia trophozoites are likely to be effective as microtubule function is not only important for the survival of trophozoites within the host, but also their extensive remodeling is necessary during the transition from trophozoites to cysts...
December 30, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27960617/nuclear-dna-replication-and-repair-in-parasites-of-the-genus-leishmania-exploiting-differences-to-develop-innovative-therapeutic-approaches
#6
Graciela Uzcanga, Eliana Lara, Fernanda Gutiérrez, Doyle Beaty, Timo Beske, Rommy Teran, Juan-Carlos Navarro, Philippe Pasero, Washington Benítez, Ana Poveda
Leishmaniasis is a common tropical disease that affects mainly poor people in underdeveloped and developing countries. This largely neglected infection is caused by Leishmania spp, a parasite from the Trypanosomatidae family. This parasitic disease has different clinical manifestations, ranging from localized cutaneous to more harmful visceral forms. The main limitations of the current treatments are their high cost, toxicity, lack of specificity, and long duration. Efforts to improve treatments are necessary to deal with this infectious disease...
December 14, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27936989/the-regulatory-mechanism-of-fungal-elicitor-induced-secondary-metabolite-biosynthesis-in-medical-plants
#7
Xin Zhai, Min Jia, Ling Chen, Cheng-Jian Zheng, Khalid Rahman, Ting Han, Lu-Ping Qin
A wide range of external stress stimuli trigger plant cells to undergo complex network of reactions that ultimately lead to the synthesis and accumulation of secondary metabolites. Accumulation of such metabolites often occurs in plants subjected to stresses including various elicitors or signal molecules. Throughout evolution, endophytic fungi, an important constituent in the environment of medicinal plants, have known to form long-term stable and mutually beneficial symbiosis with medicinal plants. The endophytic fungal elicitor can rapidly and specifically induce the expression of specific genes in medicinal plants which can result in the activation of a series of specific secondary metabolic pathways resulting in the significant accumulation of active ingredients...
December 10, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27931152/planting-the-seed-origins-composition-and-postnatal-health-significance-of-the-fetal-gastrointestinal-microbiota
#8
Lisa F Stinson, Matthew S Payne, Jeffrey A Keelan
It has long been assumed that establishment of the fetal microbiome commences with the birthing process. However, recent studies have found bacterial DNA in umbilical cord blood, placenta, amniotic fluid, meconium, and fetal membranes in healthy normal pregnancies, leading to suggestions that the seeding of the fetal microbiome may commence in utero long before delivery. The origins of the microbiota of the fetal gastrointestinal (GI) tract have not yet been conclusively determined, although bacterial translocation from the maternal circulation, or ascension from the vagina, are both likely to be contributing pathways...
December 8, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27931136/iminosugars-promising-therapeutics-for-influenza-infection
#9
Beatrice Ellen Tyrrell, Andrew Cameron Sayce, Kelly Lyn Warfield, Joanna Louise Miller, Nicole Zitzmann
Influenza virus causes three to five million severe respiratory infections per year in seasonal epidemics, and sporadic pandemics, three of which occurred in the twentieth century and are a continuing global threat. Currently licensed antivirals exclusively target the viral neuraminidase or M2 ion channel, and emerging drug resistance necessitates the development of novel therapeutics. It is believed that a host-targeted strategy may combat the development of antiviral drug resistance. To this end, a class of molecules known as iminosugars, hydroxylated carbohydrate mimics with the endocyclic oxygen atom replaced by a nitrogen atom, are being investigated for their broad-spectrum antiviral potential...
December 8, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27869522/current-aspects-of-salmonella-contamination-in-the-us-poultry-production-chain-and-the-potential-application-of-risk-strategies-in-understanding-emerging-hazards
#10
Kalavathy Rajan, Zhaohao Shi, Steven C Ricke
One of the leading causes of foodborne illness in poultry products is Salmonella enterica. Salmonella hazards in poultry may be estimated and possible control methods modeled and evaluated through the use of quantitative microbiological risk assessment (QMRA) models and tools. From farm to table, there are many possible routes of Salmonella dissemination and contamination in poultry. From the time chicks are hatched through growth, transportation, processing, storage, preparation, and finally consumption, the product could be contaminated through exposure to different materials and sources...
November 21, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27869519/a-post-planktonic-era-of-in-vitro-infectious-models-issues-and-changes-addressed-by-a-clinically-relevant-wound-like-media
#11
Urvish Trivedi, Jonas S Madsen, Kendra P Rumbaugh, Randall D Wolcott, Mette Burmølle, Søren J Sørensen
Medical science is pitted against an ever-increasing rise in antibiotic tolerant microorganisms. Concurrently, during the past decade, biofilms have garnered much attention within research and clinical practice. Although the significance of clinical biofilms is becoming very apparent, current methods for diagnostics and direction of therapy plans in many hospitals do not reflect this knowledge; with many of the present tools proving to be inadequate for accurately mimicking the biofilm phenomenon. Based on current findings, we address some of the fundamental issues overlooked by clinical labs: the paradigm shifts that need to occur in assessing chronic wounds; better simulation of physiological conditions in vitro; and the importance of incorporating polymicrobial populations into biofilm models...
November 21, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27869515/vi-capsular-polysaccharide-synthesis-virulence-and-application
#12
Xiaomei Hu, Zhijin Chen, Kun Xiong, Jing Wang, Xiancai Rao, Yanguang Cong
Vi capsular polysaccharide, a linear homopolymer of α-1,4-linked N-acetylgalactosaminuronate, is characteristically produced by Salmonella enterica serovar Typhi. The Vi capsule covers the surface of the producing bacteria and serves as an virulence factor via inhibition of complement-mediated killing and promoting resistance against phagocytosis. Furthermore, Vi also represents a predominant protective antigen and plays a key role in the development of vaccines against typhoid fever. Herein, we reviewed the latest advances associated with the Vi polysaccharide, from its synthesis and transport within bacterial cells, mechanisms involved in virulence, immunological characteristics, and applications in vaccine, as well as its purification and detection methods...
November 21, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27868469/critical-review-on-biofilm-methods
#13
Joana Azeredo, Nuno F Azevedo, Romain Briandet, Nuno Cerca, Tom Coenye, Ana Rita Costa, Mickaël Desvaux, Giovanni Di Bonaventura, Michel Hébraud, Zoran Jaglic, Miroslava Kačániová, Susanne Knøchel, Anália Lourenço, Filipe Mergulhão, Rikke Louise Meyer, George Nychas, Manuel Simões, Odile Tresse, Claus Sternberg
Biofilms are widespread in nature and constitute an important strategy implemented by microorganisms to survive in sometimes harsh environmental conditions. They can be beneficial or have a negative impact particularly when formed in industrial settings or on medical devices. As such, research into the formation and elimination of biofilms is important for many disciplines. Several new methodologies have been recently developed for, or adapted to, biofilm studies that have contributed to deeper knowledge on biofilm physiology, structure and composition...
November 21, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27824282/marine-sponge-associated-bacteria-as-a-potential-source-for-polyhydroxyalkanoates
#14
Ganesan Sathiyanarayanan, Ganesan Saibaba, George Seghal Kiran, Yung-Hun Yang, Joseph Selvin
Marine sponges are filter feeding porous animals and usually harbor a remarkable array of microorganisms in their mesohyl tissues as transient and resident endosymbionts. The marine sponge-microbial interactions are highly complex and, in some cases, the relationships are thought to be truly symbiotic or mutualistic rather than temporary associations resulting from sponge filter-feeding activity. The marine sponge-associated bacteria are fascinating source for various biomolecules that are of potential interest to several biotechnological industries...
November 8, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27822973/malodorous-volatile-organic-sulfur-compounds-sources-sinks-and-significance-in-inland-waters
#15
Susan B Watson, Friedrich Jüttner
Volatile Organic Sulfur Compounds (VOSCs) are instrumental in global S-cycling and greenhouse gas production. VOSCs occur across a diversity of inland waters, and with widespread eutrophication and climate change, are increasingly linked with malodours in organic-rich waterbodies and drinking-water supplies. Compared with marine systems, the role of VOSCs in biogeochemical processes is far less well characterized for inland waters, and often involves different physicochemical and biological processes. This review provides an updated synthesis of VOSCs in inland waters, focusing on compounds known to cause malodours...
November 8, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27822970/overlapping-riboflavin-supply-pathways-in-bacteria
#16
Víctor Antonio García-Angulo
Riboflavin derivatives are essential cofactors for a myriad of flavoproteins. In bacteria, flavins importance extends beyond their role as intracellular protein cofactors, as secreted flavins are a key metabolite in a variety of physiological processes. Bacteria obtain riboflavin through the endogenous riboflavin biosynthetic pathway (RBP) or by the use of importer proteins. Bacteria frequently encode multiple paralogs of the RBP enzymes and as for other micronutrient supply pathways, biosynthesis and uptake functions largely coexist...
November 8, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27800700/t-cell-exhaustion-in-tuberculosis-pitfalls-and-prospects
#17
Nargis Khan, Aurobind Vidyarthi, Mohammed Amir, Khurram Mushtaq, Javed Naim Agrewala
T-cells play an important role in immunity but when these cells are overexposed to specific antigens, their function may decline. This state is usually referred to as exhaustion and the T-cells show reduced proliferation and functions such as cytokine release. T-cell exhaustion has been observed in several cancers as well as in chronic infections such as tuberculosis (TB). In chronic Mycobacterium tuberculosis (Mtb) infection, T-cells may express the exhaustion phenotype and show a progressive loss of secretion of IL-2, IFN-γ and TNF-α...
November 1, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27800699/current-and-next-generation-bluetongue-vaccines-requirements-strategies-and-prospects-for-different-field-situations
#18
Femke Feenstra, Piet A van Rijn
Bluetongue virus (BTV) causes the hemorrhagic disease bluetongue (BT) in ruminants. The best way to control outbreaks is vaccination. Currently, conventionally modified-live and inactivated vaccines are commercially available, which have been successfully used to control BT, but nonetheless have their specific shortcomings. Therefore, there is a need for improved BT vaccines. The ideal BT vaccine is efficacious, safe, affordable, protective against multiple serotypes and enables the differentiation of infected from vaccinated animals...
November 1, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27800693/45-years-after-the-discovery-of-human-polyomaviruses-bk-and-jc-time-to-speed-up-the-understanding-of-associated-diseases-and-treatment-approaches
#19
Heidi Barth, Morgane Solis, Quentin Lepiller, Charlotte Sueur, Eric Soulier, Sophie Caillard, Françoise Stoll-Keller, Samira Fafi-Kremer
Nearly 45 years after the discovery of the first two human polyomaviruses BK and JC, their life-long persistence and mechanisms of pathogenesis remain poorly understood and efficient antiviral treatments are severely lacking. In this review, we sought to provide an update on recent advances in understanding the life cycle of these two viruses, particularly focusing on their interaction with the host immune system and pathogenesis. We have also discussed novel treatment approaches and highlighted areas of future research...
November 1, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27800692/waiting-in-the-wings-the-potential-of-mosquito-transmitted-flaviviruses-to-emerge
#20
Duncan R Smith
The sudden dramatic emergence of the mosquito transmitted flavivirus Zika virus has bought to the world's attention a relatively obscure virus that was previously only known to specialist researchers. The genus Flavivirus of the family Flaviviridae contains a number of well-known mosquito transmitted human pathogenic viruses including the dengue, yellow fever, Japanese encephalitis and West Nile viruses. However, the genus also contains a number of lesser known human pathogenic viruses transmitted by mosquitoes including Wesselsbron virus, Ilheus virus, St...
November 1, 2016: Critical Reviews in Microbiology
journal
journal
30230
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"