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Journal of Neuropsychiatry and Clinical Neurosciences

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https://www.readbyqxmd.com/read/28294711/potential-bedside-utility-of-the-clock-drawing-test-in-evaluating-rapid-therapeutic-response-in-the-natural-course-of-schizophrenia-a-preliminary-study
#1
Ramdas Sarjerao Ransing, Praveen Homdeorao Khairkar, Kshirod Mishra, Gajanan Sakekar
The Clock-Drawing Test (CDT) is a brief, relatively time-efficient, easy to administer at bedside, and well-proven cognitive screening test that assesses a broad range of cognitive abilities in stroke, delirium, and dementia. However, challenges of comprehensive therapeutic outcome evaluations in schizophrenia can also be potentially overcome using CDT. The authors aimed to measure the therapeutic outcome using CDT in 101 schizophrenia patients, irrespective of their diagnostic subtypes. A repeated measures analysis of variance found that improvements on CDT and the Positive and Negative Syndrome Scale were closely correlated, reflecting critical information about therapeutic response measures in schizophrenia...
March 15, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28294710/behavioral-disconnection-syndrome-manifesting-as-combined-mania-and-visual-auditory-hallucinations-secondary-to-isolated-right-thalamic-hemorrhage
#2
Parunyou Julayanont, Doungporn Ruthirago, Khondoker Alam, Yazan J Alderazi
No abstract text is available yet for this article.
March 15, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28294709/cross-lagged-panel-analysis-of-depression-and-behavioral-dysfunction-in-the-first-year-after-moderate-to-severe-traumatic-brain-injury
#3
Shannon B Juengst, John M Myrga, Jesse R Fann, Amy K Wagner
Timely treatment of depression and behavioral dysfunction after moderate-to-severe traumatic brain injury (TBI) could improve health, function, and quality of life. The authors hypothesized that 6-month depression would be the stronger contributor to later depression and behavioral dysfunction in a sample of 88 adults with moderate-to-severe TBI. A structural equation modeling cross-lagged panel analysis, adjusting for all 6-month predictors, revealed that 6-month depression had a stronger relationship to 12-month depression (βstand=0...
March 15, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28294708/sleep-patterns-and-neuropsychiatric-symptoms-in-hospitalized-patients-with-dementia
#4
Kaloyan S Tanev, Andrew Winokur, Roger K Pitman
The authors examined 28 dementia inpatients receiving treatment as usual. Beginning-to-end differences in neuropsychiatric symptoms and actigraphic sleep patterns were measured. Using a mixed-model, the authors regressed neuropsychiatric symptoms on average sleep minutes (between-subjects effect) and each night's deviation from average (within-subject effect). Sleep did not significantly differ from beginning to end of participation, whereas neuropsychiatric symptoms did. Average sleep minutes predicted average neuropsychiatric symptoms (p=0...
March 15, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28294707/outcome-of-non-invasive-brain-stimulation-in-substance-use-disorders-a-review-of-randomized-sham-controlled-clinical-trials
#5
Benoit Trojak, Anne Sauvaget, Shirley Fecteau, Laurence Lalanne, Jean-Christophe Chauvet-Gelinier, Sonja Koch, Samuel Bulteau, Daniele Zullino, Sophia Achab
Non-invasive brain stimulation (NIBS) might be a new approach to treat substance use disorders (SUD). A systematic review and critical analysis was performed to identify potential therapeutic effects of NIBS on addictions. A search of the Medline database was conducted for randomized sham-controlled trials using NIBS in the field of addiction and published until August 2016. Twenty-six studies in various SUD met the inclusion criteria. Converging evidence indicates that NIBS might be a promising mean to treat patients with alcohol and tobacco use disorders, by acting on craving reduction and other mechanisms such as improvement in cognitive dysfunctions...
March 15, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28264633/a-neurology-of-the-conservative-liberal-dimension-of-political-ideology
#6
Mario F Mendez
Differences in political ideology are a major source of human disagreement and conflict. There is increasing evidence that neurobiological mechanisms mediate individual differences in political ideology through effects on a conservative-liberal axis. This review summarizes personality, evolutionary and genetic, cognitive, neuroimaging, and neurological studies of conservatism-liberalism and discusses how they might affect political ideology. What emerges from this highly variable literature is evidence for a normal right-sided "conservative-complex" involving structures sensitive to negativity bias, threat, disgust, and avoidance...
March 7, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28264632/toward-a-neuroscience-of-politics
#7
David B Arciniegas, C Alan Anderson
No abstract text is available yet for this article.
March 7, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28238273/a-novel-approach-to-identifying-a-neuroimaging-biomarker-for-patients-with-serious-mental-illness
#8
Alok Madan, J Christopher Fowler, Michelle A Patriquin, Ramiro Salas, Philip R Baldwin, Kenia M Velasquez, Humsini Viswanath, David L Molfese, Carla Sharp, Jon G Allen, Susan Hardesty, John M Oldham, B Christopher Frueh
Serious mental illness (SMI) is disabling, and current interventions are ineffective for many. This exploratory study sought to demonstrate the feasibility of applying topological data analysis (TDA) to resting-state functional connectivity data obtained from a heterogeneous sample of 235 adult inpatients to identify a biomarker of treatment response. TDA identified two groups based on connectivity between the prefrontal cortex and striatal regions: patients admitted with greater functional connectivity between these regions evidenced less improvement from admission to discharge than patients with lesser connectivity between them...
February 27, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28238272/psychiatric-presentations-of-c9orf72-mutation-what-are-the-diagnostic-implications-for-clinicians
#9
Simon Ducharme, Sepideh Bajestan, Bradford C Dickerson, Valerie Voon
The C9orf72 mutation was identified as the most frequent genetic cause of frontotemporal dementia (FTD). In light of multiple reports of predominant psychiatric presentations of FTD secondary to C9orf72 mutation, the American Neuropsychiatric Association Committee on Research reviewed all studies on psychiatric aspects of this mutation to identify clinically relevant features for diagnosis. The most common psychiatric presentation is psychosis (21%-56%), with delusions, and/or multimodal hallucinations. Other presentations include late-onset mania and depression with cognitive impairment or catatonia...
February 27, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28238271/clozapine-treatment-for-cabergoline-induced-psychosis-in-a-patient-with-a-giant-prolactinoma
#10
Rodrigo Pérez-Esparza, Carlos Alberto Rojas-Guerrero, Gerson Geovany Andino-Rios, Patricia Arias-Garro, Jesús Ramírez-Bermúdez, Lesly Portocarrero-Ortiz
No abstract text is available yet for this article.
February 27, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28193126/predictors-of-major-depression-and-posttraumatic-stress-disorder-following-traumatic-brain-injury-a-systematic-review-and-meta-analysis
#11
Maryse C Cnossen, Annemieke C Scholten, Hester F Lingsma, Anneliese Synnot, Juanita Haagsma, Prof Ewout W Steyerberg, Suzanne Polinder
Although major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are prevalent after traumatic brain injury (TBI), little is known about which patients are at risk for developing them. The authors systematically reviewed the literature on predictors and multivariable models for MDD and PTSD after TBI. The authors included 26 observational studies. MDD was associated with female gender, preinjury depression, postinjury unemployment, and lower brain volume, whereas PTSD was related to shorter posttraumatic amnesia, memory of the traumatic event, and early posttraumatic symptoms...
February 14, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28121260/treatment-of-agitation-in-huntington-s-disease-with-electroconvulsive-therapy
#12
Rohit Praful Shah, Vinod Alluri, Sarita Sharma
No abstract text is available yet for this article.
January 25, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28121259/neurobiology-of-the-premonitory-urge-in-tourette-s-syndrome-pathophysiology-and-treatment-implications
#13
Andrea E Cavanna, Kevin J Black, Mark Hallett, Valerie Voon
Motor and vocal tics are relatively common motor manifestations identified as the core features of Tourette's syndrome (TS). Although traditional descriptions have focused on objective phenomenological observations, such as anatomical location, number and frequency of tics, patients' first-person accounts have consistently reported characteristic subjective correlates. These sensory phenomena are often described as a feeling of mounting inner tension or urge to move ("premonitory urge"), which is transiently relieved by tic expression...
January 25, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28121258/anti-nmda-receptor-antibody-positivity-and-presentations-without-seizure-involuntary-movement-hypoventilation-or-tumor-a-systematic-review-of-the-literature
#14
Bunta Yoshimura, Manabu Takaki
Patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis may remain undiagnosed and untreated with immunotherapy. To investigate specific features and responses to immunotherapy of atypical anti-NMDAR antibody positivity patients, the authors reviewed and evaluated previous case reports/series including patients without seizure, involuntary movement, hypoventilation, or tumor. Of 22 patients identified, 21 responded to immunotherapy. Two patients had neurological/motor symptoms with few/no psychiatric/cognitive symptoms, and eight had both...
January 25, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28121257/focal-changes-to-human-electrocorticography-with-drowsiness-a-novel-measure-of-local-sleep
#15
Jeremy D Slater, Mircea I Chelaru, Bryan J Hansen, Charles Beaman, Giridhar Kalamangalam, Nitin Tandon, Valentin Dragoi
Drowsiness may be defined as the progressive loss of cortical processing efficiency that occurs with time passing while awake. This loss of cortical processing efficiency is reflected in focal changes to the electroencephalogram, including islands of increased delta power concurrent with drop-offs in neuronal activity (i.e., focal cortical inactivity). The authors hypothesized that these focal changes are evidenced at individual electrodes by combination of increased instantaneous amplitude in delta band and decreased instantaneous frequency in theta-alpha band, permitting their categorization as "active" and "inactive...
January 25, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28121256/traumatic-brain-injury-in-iraq-and-afghanistan-veterans-new-results-from-a-national-random-sample-study
#16
Lisa K Lindquist, Holly C Love, Eric B Elbogen
This study randomly sampled post-9/11 military veterans and reports on causes, predictors, and frequency of traumatic brain injury (TBI) (N=1,388). A total of 17.3% met criteria for TBI during military service, with about one-half reporting multiple head injuries, which were related to higher rates of posttraumatic stress disorder, depression, back pain, and suicidal ideation. The most common mechanisms of TBI included blasts (33.1%), objects hitting head (31.7%), and fall (13.5%). TBI was associated with enlisted rank, male gender, high combat exposure, and sustaining TBI prior to military service...
January 25, 2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28145822/chronic-alcohol-use-and-sleep-homeostasis-risk-factors-and-neuroimaging-of-recovery
#17
Sarah L Martindale, Robin A Hurley, Katherine H Taber
No abstract text is available yet for this article.
2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27829318/cognitive-effects-of-rasagiline-in-mild-to-moderate-stage-parkinson-s-disease-without-dementia
#18
Laura L Frakey, Joseph H Friedman
The authors studied the effects of rasagiline on cognition in a sample of 50 nondemented patients with mild to moderate Parkinson's disease (PD) using a double-blind, placebo controlled design. Cognition and motor symptoms were assessed at baseline and after 6 months of receiving either rasagiline or placebo. Participants receiving rasagiline showed improvement in their motor symptoms of PD compared to participants receiving placebo. No significant changes in performance on neuropsychological measures of cognition were observed between the groups...
2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27578448/onconeural-antibodies-in-acute-psychiatric-inpatient-care
#19
Sverre Georg Sæther, Morten Schou, Winfried Stoecker, Bianca Teegen, Kathrin Borowski, Arne Vaaler, Daniel Kondziella, Solveig Klæbo Reitan
Paraneoplastic neurological disorders associated with onconeural antibodies often appear with neuropsychiatric symptoms. To study the prevalence of onconeural antibodies in patients admitted to acute psychiatric inpatient care, the serum of 585 such patients was tested for antibodies targeting MOG, GLRA1B, DPPX, GRM1, GRM5, DNER, Yo, ZIC4, GAD67, amphiphysin, CV2, Hu, Ri, Ma2, and recoverin. Only one sample was positive (antirecoverin IgG). The present findings suggest that serum onconeural antibody positivity is rare among patients acutely admitted for inpatient psychiatric care...
2017: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27578447/cortical-thickness-and-anxiety-symptoms-among-cognitively-normal-elderly-persons-the-mayo-clinic-study-of-aging
#20
Anna Pink, Scott A Przybelski, Janina Krell-Roesch, Gorazd B Stokin, Rosebud O Roberts, Michelle M Mielke, Kathleen A Spangehl, David S Knopman, Clifford R Jack, Ronald C Petersen, Yonas E Geda
The authors conducted a cross-sectional study to investigate the association between anxiety symptoms and cortical thickness, as well as amygdalar volume. A total of 1,505 cognitively normal participants, aged ≥70 years, were recruited from the Mayo Clinic Study of Aging in Olmsted County, Minnesota, on whom Beck Anxiety Inventory and 3T brain MRI data were available. Even though the effect sizes were small in this community-dwelling group of participants, anxiety symptoms were associated with reduced global cortical thickness and reduced thickness within the frontal and temporal cortex...
2017: Journal of Neuropsychiatry and Clinical Neurosciences
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