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Biomedical and Environmental Sciences: BES

Yuan Li, Jing Lei Wang, Xiao Chang Zhang, Dan Liu, Wen Hui Shi, Xiao Feng Liang, Jing Wu
The standardized hypertension management provided by primary health care workers is an important part of China's recent health care reform efforts. Investigating 5,116 hypertensive patients from a cross-sectional survey conducted by the Chinese Center for Disease Control and Prevention in 2012, this study found that adherence to standardized hypertension management is associated with positive effects on hypertension- related knowledge, healthy lifestyle behavior, antihypertensive medical treatments, and blood pressure control...
December 2016: Biomedical and Environmental Sciences: BES
Jiu Kun Jiang, Wen Fang, Lin Hui Gu, Yuan Qiang Lu
2,4-dinitrophenol (DNP), an organic compound which frequently used in industry, is considered to have high toxicity. This study aimed to investigate the early changes of lymphocyte subpopulations in patients with occupational 2,4-DNP poisoning. Totally 9 patients with acute occupational 2,4-DNP poisoning and 30 healthy volunteers as control were enrolled. The patients received immediately comprehensive supportive treatments, including large-dose glucocorticoid and repeated hemoperfusion (HP). The ratio of CD4+/CD8+ T cells were significantly higher in patients upon admission compared to healthy controls (P < 0...
December 2016: Biomedical and Environmental Sciences: BES
Jiu Wei Li, Xiao Yan Gao, Yun Wu, Shi Hong Fu, Xiao Juan Tan, Yu Xi Cao, Wei Hua Zhang, Zun Dong Yin, Ying He, Yi Xing Li, Guo Dong Liang, Wen Bo Xu, Fang Fang, Huan Yu Wang
Fifteen pediatric cases of suspected Japanese encephalitis (JE) were reported in Beijing Children's Hospital during the late summer of 2013. The clinical manifestations in most cases included high fever, seizures, and abnormal magnetic resonance imaging findings. Twelve of 15 cases were laboratory-confirmed as JE cases by pathogen identification. Epidemiological investigations showed that five of the 12 laboratory-confirmed patients had an incomplete JE vaccination history. Follow-up investigations after discharge indicated that seven laboratory-confirmed JE patients without JE vaccinations had relatively poor prognoses, with an average Modified Rankin Scale (MRS) score of 2...
December 2016: Biomedical and Environmental Sciences: BES
Hai Xian Jia, Jun Hua Han, Hu Zhong Li, Dong Liang, Tao Tao Deng, Su Ying Chang
In the Chinese national nutrition surveys, fortified foods were not investigated separately from the base diet, and the contribution of fortified foods to micronutrients intake is not very clear. This study investigated the diet, including fortified foods and food supplements, of urban pregnant women and analyzed the intake of calcium, iron, and zinc to assess the corresponding contributions of fortified foods, food supplements, and the base diet. The results demonstrated that the base diet was the major source of calcium, iron, and zinc, and was recommended to be the first choice for micronutrients intake...
December 2016: Biomedical and Environmental Sciences: BES
Wei Ming Yuan, Yuan Qiang Lu, Zheng Wei, Ming Chen, Sheng Liang He, Wen Yuan Mai, Mei Bian Zhang
Emergencies of epistaxis in students caused by environmental pollution have rarely been reported to date. This study aimed to explore the cause of an emergency of epistaxis in elementary students by using a field epidemiological investigation. Twenty-two epistaxis cases from a single school with differences in gender, age, and classroom, were diagnosed within a period of 7 days. The air concentration of chromic acid mist (Cr6+) in the electroplating factory area, new campus, and residential area exceeded the limit of uncontrolled emissions...
December 2016: Biomedical and Environmental Sciences: BES
Lei Gao, Shan Shan Cui, Yu Han, Wei Dai, Yuan Yuan Su, Xin Zhang
OBJECTIVE: This study aimed to explore the association between periconceptional fish consumption by parents and autism spectrum disorder (ASD) and intelligence deficiency (ID). METHODS: A case-control study was conducted through a questionnaire with 108 ASD cases, 79 ID cases, and 108 controls. The ASD and ID cases were students from special educational schools in Tianjin from 2012 to 2014. The age- and sex-matched controls were from a high school, three primary schools, and a kindergarten in Tianjin...
December 2016: Biomedical and Environmental Sciences: BES
Hui Gao, Ling Yu Li, Man Zhang, Quan Zhang
OBJECTIVE: This paper aims to investigate the apoptotic effect of inactivated Sendai virus (hemagglutinating virus of Japan-enveloped, HVJ-E) on murine melanoma cells (B16F10) and the possible mechanisms involved in the putative apoptotic reactions. METHODS: B16F10 cells were treated with HVJ-E at various multiplicities of infection (MOI), and the reactive oxygen species (ROS), cell viability, and apoptosis were measured. Next, the roles of ROS in the regulation of Bcl-2/Bax and the activation of mitogen-activated protein kinase (MAPK) pathways in HVJ-E-treated B16F10 cells were analyzed...
December 2016: Biomedical and Environmental Sciences: BES
Yong Kang Tao, Pu Lin Yu, Yong Ping Bai, Sheng Tao Yan, Shui Ping Zhao, Guo Qiang Zhang
OBJECTIVE: PERK/eIF2α/CHOP is a major signaling pathway mediating endoplasmic reticulum (ER) stress related with atherosclerosis. Oxidized LDL (ox-LDL) also induces endothelial apoptosis and plays a vital role in the initiation and progression of atherosclerosis. The present study was conducted to explore the regulatory effect of ox-LDL on PERK/eIF2α/CHOP signaling pathway in vascular endothelial cells. METHODS: The effects of ox-LDL on PERK and p-eIF2α protein expression of primary human umbilical vein endothelial cells (HUVECs) were investigated by Western blot analysis...
December 2016: Biomedical and Environmental Sciences: BES
Pravin Suryakantrao Deshmukh, Kanu Megha, Namita Nasare, Basu Dev Banerjee, Rafat Sultana Ahmed, Mahesh Pandurang Abegaonkar, Ashok Kumar Tripathi, Pramod Kumari Mediratta
OBJECTIVE: The present study was designed to investigate the effects of subchronic low level microwave radiation (MWR) on cognitive function, heat shock protein 70 (HSP70) level and DNA damage in brain of Fischer rats. METHODS: Experiments were performed on male Fischer rats exposed to microwave radiation for 90 days at three different frequencies: 900, 1800, and 2450 MHz. Animals were divided into 4 groups: Group I: Sham exposed, Group II: animals exposed to microwave radiation at 900 MHz and specific absorption rate (SAR) 5...
December 2016: Biomedical and Environmental Sciences: BES
Lian Guo Fu, Li Li Sun, Shao Wei Wu, Yi De Yang, Xiao Hui Li, Zheng He Wang, Lu Wu, Fu Zhi Wang, Jun Ma
OBJECTIVE: To explore the influence of secular trends in body height and weight on the prevalence of overweight and obesity among Chinese children and adolescents. METHODS: The data were obtained from five cross-sectional Chinese National Surveys on Students' Constitution and Health. Overweight/obesity was defined as BMI-for-age Z-score of per the Wold Health Organization (WHO) reference values. Body height and weight for each sex and age were standardized to those reported in 1985 (standardized height: SHY; standardized weight: SWY) and for each sex and year at age 7 (standardized height: SHA; standardized weight: SWA) using the Z-score method...
December 2016: Biomedical and Environmental Sciences: BES
Yan Li Wei, Jun Sheng Huo, Jing Sun, Hui Liu, Gang Qiang Ding, Rong Hua Zhang, Jin Bin Luo, Zhen Xin Lu, Jun Shi Chen
No abstract text is available yet for this article.
November 2016: Biomedical and Environmental Sciences: BES
Pablo A Lizana, Cisternas-Vallejos Paula, Leonel Araya, Francisco Aguilera, Manuel Mora
This study analyze the relation between body composition, physical activity (PA), and sex in Chilean children from rural and urban public educational institutions. The prevalence of obesity (according to BMI) was 30.88% in urban children and 28.93% in rural children. Central obesity presented mainly in the rural girls. Approximately 90% of the participants reported <7 h of PA/week, regardless of residential area. In addition, central fat was strongly associated with rural residence; the children reported lower PA levels, and they presented a higher prevalence of central fat...
November 2016: Biomedical and Environmental Sciences: BES
Qin Wu, Jie Ren, Li Chen Yang, Jie Liu, Jun Wei, Wei Zhang, Na Li, Yue Jiao Wang, Li Huang Yan, Jian Rong Ma, Xiao Guang Yang
Iron deficiency anemia is one of the most prevalent nutritional deficiency worldwide. The commonly used cut-off values for identifying iron deficiency are extrapolated from older children and may not be suitable for infants. Therefore, our study aimed to establish appropriate cut-off values for the evaluation of iron status in Chinese infants. Pregnant women who delivered at ⋝37 gestational weeks with normal iron status were recruited. Later, infants with normal birth weight and who were breastfed in the first 4 months were selected...
November 2016: Biomedical and Environmental Sciences: BES
Mohammad Naderi, Mohammad Hashemi, Hamideh Mirshekari, Gholamreza Bahari, Mohsen Taheri
A case-control study was carried out that involved 203 individuals diagnosed with pulmonary tuberculosis (PTB) and 203 healthy subjects. Genotyping of TLR1 rs5743551 and rs5743618 polymorphisms was done using polymerase chain reaction-restriction fragments length polymorphism assay. We found that TLR1 rs5743551 variant affected the risk of PTB in the codominant (OR=3.28, 95% CI=1.98-5.45, P<0.0001, GA vs. GG; OR=1.86, 95% CI=1.05-3.28, P=0.033, AA vs. GG) and dominant (OR=2.69, 95% CI=1.67-4.34, P<0.0001, GA+AA vs...
November 2016: Biomedical and Environmental Sciences: BES
Li Qin Su, Yin Long Jin, Frederick W Unverzagt, Yi Bin Cheng, Ann M Hake, Liao Ran, Feng Ma, Jing Yi Liu, Chen Chen, Jian Chao Bian, Xian Ping Wu, Sujuan Gao
This cross-sectional study aimed to examine the association between selenium levels and diabetes in an older population with life-long natural exposure to selenium in rural China. A total of 1856 subjects aged 65 years or older from four Chinese rural counties with different environmental selenium levels were evaluated. Analysis of covariance models and logistic regression models were used to examine the relationship between nail selenium levels and serum glucose, serum insulin, insulin resistance [using the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR)], and the risk of diabetes...
November 2016: Biomedical and Environmental Sciences: BES
Lu Zhang, Ming Zhang, Jin Jin Wang, Chong Jian Wang, Yong Cheng Ren, Bing Yuan Wang, Hong Yan Zhang, Xiang Yu Yang, Yang Zhao, Cheng Yi Han, Jun Mei Zhou, Chao Pang, Lei Yin, Jing Zhi Zhao, Xin Ping Luo, Dong Sheng Hu
This cohort study was designed to evaluate the association of transcription factor 7-like 2 (TCF7L2) and proglucagon gene (GCG) variants with disordered glucose metabolism and the incidence of type 2 diabetes mellitus (T2DM) in a rural adult Chinese population. A total of 7,751 non-T2DM participants ⋝18 years old genotyped at baseline were recruited. The same questionnaire interview and physical and blood biochemical examinations were performed at both baseline and follow-up. During a median 6 years of follow-up, T2DM developed in 227 participants...
November 2016: Biomedical and Environmental Sciences: BES
Wen Jiao Yin, Li Ping Shen, Fu Zhen Wang, Guo Min Zhang, Hui Zheng, Feng Wang, Tie Zhu Liu, Qing Ling Meng, Yao Yi, Fu Qiang Cui, Sheng Li Bi
OBJECTIVE: To determine the hepatitis B immunoprophylactic failure rate in infants born to hepatitis B virus (HBV) infected mothers and to characterize HBV genes. METHODS: HBV-serological testing was conducted for pregnant women and infants. The complete genomes of 30 HBV isolates were sequenced, and genetic characteristics were analyzed using MEGA 5 software. RESULTS: The immunoprophylactic failure rate for infants who had completed the scheduled hepatitis B vaccination program was 5...
November 2016: Biomedical and Environmental Sciences: BES
Jing Song, Ying Liu, Hui Fang Zhang, Qiao Niu
OBJECTIVE: To explore the role of RAS/PI3K pathway in the impairment of long-term potentiation (LTP) induced by acute aluminum (Al) treatment in rats in vivo. METHODS: First, different dosages of aluminum-maltolate complex [Al(mal)3] were given to rats via acute intracerebroventricular (i.c.v.) injection. Following Al exposure, the RAS activity of rat hippocampus were detected by ELISA assay after the hippocampal LTP recording by field potentiation technique in vivo...
November 2016: Biomedical and Environmental Sciences: BES
Qing Jun Jia, Xin Yu Chen, De Zhou Li, Juan Juan Xu, Zhi Gang Xu, Zhi Liang Duan, Jin Sheng Wen
In the present study, the complete genomes of four common (4/EV71/Wenzhou/CHN/2014, 15/ EV71/Wenzhou/CHN/2014, 116/EV71/Wenzhou/ CHN/2014, and 120/EV71/Wenzhou/CHN/2014) and two virulent (11/EV71/Wenzhou/CHN/2014 and 109/EV71/Wenzhou/CHN/2014) enterovirus 71 (EV71) isolates were sequenced and described. They are 7405 bp in length and belong to EV71 sub-genotype C4 (C4a cluster). Nucleotide sequence alignment revealed six nucleotide variations (GP151→TP151, GP199→AP199, GP261→TP261, AP328→CP328, GP422→AP422, and GP437→TP437) in the two virulent isolates within the 5'UTR of the IRES element...
October 2016: Biomedical and Environmental Sciences: BES
A E Khatab, N M Hashem, L M El-Kodary, F M Lotfy, G A Hassan
The prophylactic effects of Chinese propolis against cypermethrin toxicity were evaluated by performing ovary and uterus histopathology, as well as by characterizing ovarian function, embryos, and litters. Cypermethrin induced atypia in the ovary and uterus, and decreased the ovulation sites and the number of embryos. Cypermethrin-induced oxidative stress during pregnancy, decreased the parturition rate as well as the number and weight of offspring and increased the incidence of morphological malformations in the offspring...
October 2016: Biomedical and Environmental Sciences: BES
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