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Biomedical and Environmental Sciences: BES

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https://www.readbyqxmd.com/read/28705272/measurement-and-assessment-of-physical-activity-by-information-and-communication-technology
#1
Qun Zhang, Xi Yang, Dan Liu, Wen Hua Zhao
This study provides explorative insights into the information and communication technology (ICT) for promoting the physical activity level. ICT has provided innovative ideas and perspectives for PA measurement, assessment, evaluation and health intervention. ICT that aims to increase exercise for the entire population should be of a well-oriented and easy-to-use design with the options of tailored and personalized feedback, coaching, and ranking and supporting; it should be capable of setting goals and working with a schedule and be accompanied by a website to provide overviews of the users' exercise results and progress...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705271/molecular-and-epidemiological-characterization-of-infant-botulism-in-beijing-china
#2
Yin Ping Dong, Wei Wang, Tao Jiang, Jin Xu, Chun Hui Han, Shao Fei Yan, Séamus Fanning, Ying Li, Xiao Chen Ma, Di Zhang, Yao Zhao, Biao Zeng, Feng Qin Li
Laboratory-based pathogen isolation, identification, and toxicity determination were performed on samples from a suspected case of infant botulism. Mice injected with cultures generated from the enema sample and ingested Powered infant formula (PIF) presented typical signs of botulism. Antitoxins to polyvalent botulinum neurotoxins (BoNTs) and monovalent BoNT type B antitoxin had protective effects. Clostridium botulinum isolated from the enema and residual PIF samples were positive for type B toxin. Pulsed-field gel electrophoresis (PFGE) revealed that the two strains of C...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705270/serum-fetuin-a-levels-and-thyroid-function-inmiddle-aged-and-elderly-chinese
#3
Xin Ru Deng, Lin Ding, Tian Ge Wang, Min Xu, Jie Li Lu, Mian Li, Zhi Yun Zhao, Yu Hong Chen, Yu Fang Bi, Yi Ping Xu, Yu Xu
Serum fetuin-A levels are reportedly elevated in hyperthyroidism. However, there are few relevant epidemiologic studies. We conducted a cross-sectional study in Songnan community, China in 2009 to investigate the association between serum fetuin-A concentrations and thyroid function. A total of 2,984 participants aged 40 years and older were analyzed. Multivariable linear regression analysis revealed that serum fetuin-A concentra- tions were positively associated with log (free triiodothyronine) and were inversely associated with log (thyroid peroxidase antibody) after adjustment (both P < 0...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705269/regional-variations-in-medication-usage-for-cardiovascular-diseases-at-the-community-level-in-china-pure-china-study
#4
Jin Gang Yang, Hong Qiu Gu, Jian Bo, Yang Wang, Wei Li
We investigated the usage of secondary prevention drugs and traditional Chinese medicine (TCM) products in individuals with cardiovascular diseases (CVDs) at the community level in China. Among 2,407 participants with self-reported coronary heart disease (CHD) and 872 with stroke, nearly 80% of individuals with CHD and 73% of individuals with stroke were not taking any proven secondary prevention drug. However, 32.9% of them took TCM products. Patients with CVDs in rural areas used less secondary prevention treatment, but more TCM products than their counterparts in the urban regions...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705268/description-and-factors-affecting-the-referral-of-presumptive-tuberculosis-patients-in-china
#5
Tao Li, Hui Zhang, Li Xia Wang, Yu Pang, Xin DU
To describe and analyze the factors affecting the referral of presumptive tuberculosis patients between health-care facilities that are not affiliated with the National TB Control Program (NTP) and NTP-designated medical facilities in China, we carried out a retrospective study based on data collected in the Tuberculosis Information Management System in 2015. Out of 324,221 presumptive pulmonary tuberculosis (PTB) cases reported by non-NTP health-care facilities, 302,006 (93.1%) reported cases successfully arrived at designated medical facilities and 22,215 cases (6...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705267/acrylamide-induced-subacute-neurotoxic-effects-on-the-cerebral-cortex-and-cerebellum-at-the-synapse-level-in-rats
#6
Bin Zhang, Hua Shao, Xiu Hui Wang, Xiao Chen, Zhong Sheng Li, Peng Cao, Dan Zhu, Yi Guang Yang, Jing Wei Xiao, Bin Li
OBJECTIVE: To investigate acrylamide (ACR)-induced subacute neurotoxic effects on the central nervous system (CNS) at the synapse level in rats. METHODS: Thirty-six Sprague Dawley (SD) rats were randomized into three groups, (1) a 30 mg/kg ACR-treated group, (2) a 50 mg/kg ACR-treated group, and (3) a normal saline (NS)-treated control group. Body weight and neurological changes were recorded each day. At the end of the test, cerebral cortex and cerebellum tissues were harvested and viewed using light and electron microscopy...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705266/a-new-method-for-blood-nt-probnp-determination-based-on-a-near-infrared-point-of-care-testing-device-with-high-sensitivity-and-wide-scope
#7
Xiao Guang Zhang, Yao Gen Shu, Ju Gao, Xuan Wang, Li Peng Liu, Meng Wang, Yu Xi Cao, Yi Zeng
OBJECTIVE: To develop a rapid, highly sensitive, and quantitative method for the detection of NT-proBNP levels based on a near-infrared point-of-care diagnostic (POCT) device with wide scope. METHODS: The lateral flow assay (LFA) strip of NT-proBNP was first prepared to achieve rapid detection. Then, the antibody pairs for NT-proBNP were screened and labeled with the near-infrared fluorescent dye Dylight-800. The capture antibody was fixed on a nitrocellulose membrane by a scribing device...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705265/comparison-of-histological-microbiological-and-molecular-methods-in-diagnosis-of-patients-with-tbln-having-different-anti-tb-treatment-background
#8
Nan Ying Che, Shao Jun Huang, Yan Ma, Yi Han, Zi Chen Liu, Chen Zhang, Jing Mu, Dan Zhao, Yang Qu, Hai Qing Zhang, Zhi Dong Liu, Shao Fa Xu
OBJECTIVE: The influence of anti-tuberculosis (TB) treatment history on tuberculous lymphadenitis (TBLN) diagnosis is unclear. Therefore, this study aims to evaluate the diagnostic methods, including histology, microbiology, and molecular tests, used for TBLN. METHODS: In this study, suspected patients with TBLN and having different anti-TB treatment background were enrolled. All the samples were tested simultaneously by histology, Ziehl-Neelsen (ZN) staining, mycobacterial culture (culture), Xpert MTB/RIF (xpert), real-time PCR, and high-resolution melting curve PCR (HRM)...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705264/uptake-of-hiv-self-testing-among-men-who-have-sex-with-men-in-beijing-china-a-cross-sectional-study
#9
Xian Long Ren, Zun You Wu, Guo Dong Mi, Jennifer McGoogan, Ke Ming Rou, Yan Zhao
OBJECTIVE: To examine HIV self-testing uptake and its determinates among men who have sex with men (MSM) in Beijing, China. METHODS: A cross-sectional online survey was conducted in Beijing, China in 2016. Participants were users of a popular Chinese gay networking application and had an unknown or negative HIV status. Univariate and multivariate logistic regression analyses were conducted to examine factors associated with HIV self-testing based on adjusted odds ratio (AOR) and 95% confidence interval (CI)...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705263/antiviral-activity-of-dual-acting-hydrocarbon-stapled-peptides-against-hiv-1-predominantly-circulating-in-china
#10
Yan Wang, Francesca Curreli, Wei Si Xu, Zhen Peng Li, De Sheng Kong, Li Ren, Kun Xue Hong, Shi Bo Jiang, Yi Ming Shao, Asim K Debnath, Li Ying Ma
OBJECTIVE: New rationally designed i,i+7-hydrocarbon-stapled peptides that target both HIV-1 assembly and entry have been shown to have antiviral activity against HIV-1 subtypes circulating in Europe and North America. Here, we aimed to evaluate the antiviral activity of these peptides against HIV-1 subtypes predominantly circulating in China. METHODS: The antiviral activity of three i,i+7-hydrocarbon-stapled peptides, NYAD-36, NYAD-67, and NYAD-66, against primary HIV-1 CRF07_BC and CRF01_AE isolates was evaluated in peripheral blood mononuclear cells (PBMCs)...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28705262/zinc-absorption-from-representative-diet-in-a-chinese-elderly-population-using-stable-isotope-technique
#11
Ya Jie Li, Min Li, Xiao Bing Liu, Tong Xiang Ren, Wei Dong Li, Chun Yang, Meng Wu, Lin Li Yang, Yu Xia Ma, Jun Wang, Jian Hua Piao, Li Chen Yang, Xiao Guang Yang
OBJECTIVE: To determine the dietary zinc absorption in a Chinese elderly population and provide the basic data for the setting of zinc (Zn) recommended nutrient intakes (RNI) for Chinese elderly people. METHODS: A total of 24 elderly people were recruited for this study and were administered oral doses of 3 mg 67Zn and 1.2 mg dysprosium on the fourth day. The primary macronutrients, energy, and phytic acid in the representative diet were examined based on the Chinese National Standard Methods...
June 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549496/mutual-impact-of-diabetes-mellitus-and-tuberculosis-in-china
#12
Jun Cheng, Hui Zhang, Yan Lin Zhao, Li Xia Wang, Ming Ting Chen
China has a double burden of diabetes mellitus and tuberculosis, and many studies have been carried out on the mutual impact of these two diseases. This paper systematically reviewed studies conducted in China covering the mutual impact of epidemics of diabetes and tuberculosis, the impact of diabetes on multi-drug resistant tuberculosis and on the tuberculosis clinical manifestation and treatment outcome, the yields of bi-directional screening, and economic evaluation for tuberculosis screening among diabetes patients...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549495/detection-of-the-urinary-biomarkers-pyd-ctx-ii-and-dpd-in-patients-with-kashin-beck-disease-in-the-qinghai-province-of-china
#13
Zhi Jun Zhao, Guang Lan Pu, Pei Zhen Zhan, Qiang Li, Chun Ning Wu, Li Hua Wang
Kashin-Beck disease (KBD) is an endemic degenerative osteoarthropathy of uncertain etiology. The aim of our study was to identify changes in C-telopeptide of type II collagen (CTX-II), pyridinoline (PYD), and deoxypyridinoline (DPD) among KBD patients. 54 KBD patients and 78 healthy controls were included this study. Urinary samples were collected and measured by ELISA. The median quantities of PYD, CTX-II, and DPD of KBD patients were 1107.73 ng/μmol.cre, 695.11 ng/μmol.cre, and 1342.34 pml/μmol.cre, while the median quantities of healthy controls were 805...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549494/antimicrobial-susceptibility-testing-and-molecular-characterization-of-mycobacterium-fortuitum-isolates-in-china
#14
Hui Wen Zheng, Yu Pang, Guang Xue He, Yuan Yuan Song, Yan Lin Zhao
We performed molecular identification of clinical isolates of Mycobacterium fortuitum (M. fortuitum) and conducted drug susceptibility testing to analyze the in vitro susceptibility of clinical M. fortuitum isolates and potential molecular mechanism conferring resistance to fluoroquinolone and macrolide drugs. The results showed that moxifloxacin had the highest in vitro activity against M. fortuitum, and most M. fortuitum isolates were resistant to clarithromycin and linezolid in China. The loss of genetic mutation in clarithromycin- and amikacin-resistant isolates indicates that some other intrinsic mechanism conferring clarithromycin and amikacin resistance plays an essential role in M...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549493/the-adverse-effect-of-the-2-1-1-regimen-for-rabies-pep-in-preschool-children
#15
Shu Qing Liu, Xiao Yan Tao, Peng Cheng Yu, Chun Qiu Jin, Hong Jie Yu, Mei Shun Chen, Wu Yang Zhu
Post-exposure prophylaxis (PEP) has proved to be the most important measure for rabies prevention and control. There is little information regarding adverse reactions to the Essen and 2-1-1 regimens in preschool children (aged 0-6). We reexamined the outcomes of 1,109 preschool children who were vaccinated using SPEEDA under the Essen regimen between January 2011 and December 2012 and 1,267 preschool children under the 2-1-1 regimen between January 2013 and December 2014. We find that, in preschool children, the febrile reaction after the first 2-dose injection in the 2-1-1 regimen was significantly higher than that induced by the first 1-dose in the Essen procedure...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549492/ginsenoside-rb1-attenuates-isoflurane-surgery-induced-cognitive-dysfunction-via-inhibiting-neuroinflammation-and-oxidative-stress
#16
Hui Hui Miao, Ye Zhang, Guan Nan Ding, Fang Xiao Hong, Peng Dong, Ming Tian
OBJECTIVE: Anesthetic isoflurane plus surgery has been reported to induce cognitive impairment. The underlying mechanism and targeted intervention remain largely to be determined. Ginsenoside Rb1 was reported to be neuroprotective. We therefore set out to determine whether ginsenoside Rb1 can attenuate isoflurane/surgery-induced cognitive dysfunction via inhibiting neuroinflammation and oxidative stress. METHODS: Five-months-old C57BL/6J female mice were treated with 1...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549491/increased-chondrocyte-apoptosis-in-kashin-beck-disease-and-rats-induced-by-t-2-toxin-and-selenium-deficiency
#17
Hao Jie Yang, Ying Zhang, Zhi Lun Wang, Sen Hai Xue, Si Yuan Li, Xiao Rong Zhou, Meng Zhang, Qian Fang, Wen Jun Wang, Chen Chen, Xiang Hua Deng, Jing Hong Chen
OBJECTIVE: To investigate chondrocyte apoptosis and the expression of biochemical markers associated with apoptosis in Kashin-Beck disease (KBD) and in an established T-2 toxin- and selenium (Se) deficiency-induced rat model. METHODS: Cartilages were collected from the hand phalanges of five patients with KBD and five healthy children. Sprague-Dawley rats were administered a selenium-deficient diet for 4 weeks prior to T-2 toxin exposure. The apoptotic chondrocytes were observed by terminal deoxynucleotidyl transferase dUTP nick end labeling staining...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549490/whole-genome-analysis-reveals-new-insights-into-macrolide-resistance-in-mycoplasma-pneumoniae
#18
Shao Li Li, Hong Mei Sun, Bao Li Zhu, Fei Liu, Han Qing Zhao
OBJECTIVE: Mutations in 23S rRNA gene are known to be associated with macrolide resistance in Mycoplasma pneumoniae (M. pneumoniae). However, these mutations alone do not fully explain the high resistance rates in Asia. The aim of this study was to investigate other possible mutations involved in macrolide resistance in M. pneumoniae. METHODS: The whole genomes of 10 clinical isolates of M. pneumoniae with macrolide resistance were sequenced by Illumina HiSeq2000 platform...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549489/blood-pressure-associated-with-arsenic-methylation-and-arsenic-metabolism-caused-by-chronic-exposure-to-arsenic-in-tube-well-water
#19
Bing Gan Wei, Bi Xiong Ye, Jiang Ping Yu, Lin Sheng Yang, Hai Rong Li, Ya Juan Xia, Ke Gong Wu
OBJECTIVE: The effects of arsenic exposure from drinking water, arsenic metabolism, and arsenic methylation on blood pressure (BP) were observed in this study. METHODS: The BP and arsenic species of 560 participants were determined. Logistic regression analysis was applied to estimate the odds ratios of BP associated with arsenic metabolites and arsenic methylation capability. RESULTS: BP was positively associated with cumulative arsenic exposure (CAE)...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28549488/microwave-induced-apoptosis-and-cytotoxicity-of-nk-cells-through-erk1-2-signaling
#20
Li Zhao, Jing Li, Yan Hui Hao, Ya Bing Gao, Shui Ming Wang, Jing Zhang, Ji Dong, Hong Mei Zhou, Shu Chen Liu, Rui Yun Peng
OBJECTIVE: To investigate microwave-induced morphological and functional injury of natural killer (NK) cells and uncover their mechanisms. METHODS: NK-92 cells were exposed to 10, 30, and 50 mW/cm2 microwaves for 5 min. Ultrastructural changes, cellular apoptosis and cell cycle regulation were detected at 1 h and 24 h after exposure. Cytotoxic activity was assayed at 1 h after exposure, while perforin and NKG2D expression were detected at 1 h, 6 h, and 12 h after exposure...
May 2017: Biomedical and Environmental Sciences: BES
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