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Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists

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https://www.readbyqxmd.com/read/29307445/plan-quality-comparison-between-4-arc-and-6-arc-noncoplanar-volumetric-modulated-arc-stereotactic-radiotherapy-for-the-treatment-of-multiple-brain-metastases
#1
Kotaro Yoshio, Toshiharu Mitsuhashi, Akihisa Wakita, Takahiro Kitayama, Kento Hisazumi, Daisaku Inoue, Tsuyoki Shiode, Shiro Akaki, Susumu Kanazawa
To compare the plans of 4-arc and 6-arc noncoplanar volumetric modulated arc stereotactic radiotherapy (VMA-SRT) for multiple brain metastases and to investigate the cutoff value for the tumor number and volume for 6-arc rather than 4-arc VMA-SRT. We identified 24 consecutive multiple-target cases (3 to 19 targets in each case) with 189 total targets. We constructed plans using both 4- and 6-arc noncoplanar VMA-SRT. The prescribed dose was 36 Gy/6 fr, and it was delivered to 95% of the planning target volume (PTV)...
January 4, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29306538/comparison-of-calculated-dose-distributions-reported-as-dose-to-water-and-dose-to-medium-for-intensity-modulated-radiotherapy-of-nasopharyngeal-cancer-patients
#2
Ðeni Smilović Radojčić, Manda Švabić Kolacio, Milan Radojčić, David Rajlić, Božidar Casar, Dario Faj, Slaven Jurković
Advanced dose calculation algorithms for radiation therapy treatment planning can report external beam photon dose 2-sided, in terms of dose-to-medium (Dm) and dose-to-water (Dw). The purpose of our study was to determinate the effect of Dw and Dm reporting modes built in Elekta Monaco treatment planning system on intensity-modulated radiotherapy dose distributions for patients with nasopharyngeal cancer. For 13 patients involved in this retrospective study, 2 plans were created: 1 using Dw and another according to Dm reporting mode...
January 4, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29289456/the-potential-for-increased-tumor-control-probability-in-non-small-cell-lung-cancer-with-a-hypofractionated-integrated-boost-to-the-gross-tumor-volume
#3
Cathy Fleming, Serena O'Keeffe, Mary Dunne, John G Armstrong, Brendan McClean, Luis Leon Vintro
Treatment outcomes in locally advanced non-small cell lung cancer (NSCLC) to date have been poor, with normal tissue toxicity often limiting the dose that can be delivered to the tumor. Treatment intensification in NSCLC via targeted dose escalation with modern delivery techniques may offer the potential for a significant increase in tumor control probability (TCP) without a clinically significant increase in organ-at-risk (OAR) toxicity. In this planning study, 20 patients were re-planned with a volumetric modulated arc therapy (VMAT) and an inhomogeneous dose distribution with iteratively escalated doses to the gross tumor volume (iGTV) (composite GTV across multiple 4-dimensional computed tomography [4DCT] phases) in a series of 20 fraction regimes...
December 27, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29287919/when-and-how-to-treat-an-imrt-patient-on-a-second-accelerator-without-replanning
#4
Teh Lin, Murshed Hossain, Jiajin Fan, C-M Charlie Ma
When a linear accelerator is unavailable for treatment, a clinical decision is imminent regarding whether a patient should be treated on a linear accelerator other than the machine the patient was scheduled on, or whether treatment should be postponed until the original Linac becomes available. This work investigates the feasibility of switching patients to different accelerators for intensity-modulated radiation therapy (IMRT). We have performed Monte Carlo simulations of photon beams from different Linac models and vendors...
December 26, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29277249/fine-tuning-the-normal-tissue-objective-in-eclipse-for-lung-stereotactic-body-radiation-therapy
#5
James P Bell, Pretesh Patel, Kristin Higgins, Mark W McDonald, Justin Roper
The purpose of this study was to characterize the effects of the normal tissue objective (NTO) on lung stereotactic body radiation therapy (SBRT) dose distributions. The NTO is a spatially varying constraint used in Eclipse to limit dose to normal tissues by steepening the dose gradient. However, the multitude of potential NTO setting combinations challenges optimal NTO tuning. In the present study, a broad range of NTO settings are investigated for lung SBRT treatment planning with volumetric modulated arc therapy(VMAT)...
December 22, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29254804/in-regard-to-the-paper-patient-performance-based-plan-parameter-optimization-for-prostate-cancer-in-tomotherapy-cao-yj-lee-s-chang-kh-shim-jb-kim-kh-park-yj-kim-cy-med-dosim-2015-40-4-285-9-doi-10-1016-j-meddos-2015-03-005-epub-2015-apr-11
#6
LETTER
Reena Phurailatpam, Priyanka Agarwal, Siji Nojin Paul, Jamema Sv
No abstract text is available yet for this article.
December 15, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29254803/clinical-implementation-of-radiosurgery-using-the-helical-tomotherapy-unit
#7
Cheng B Saw, Carol Gillette, Christopher A Peters, Lawrence Koutcher
The American Society of Radiation Oncology has recently recommended the use of radiosurgery to manage brain metastases. For such a recommendation to be implemented in a widespread manner, radiosurgery must be accessible at community radiation therapy facilities. The work presented here describes our clinical experience in the implementation of radiosurgery using a Helical TomoTherapy unit. Helical TomoTherapy is a unique dose-delivery system designed to perform intensity-modulated radiation therapy (IMRT). The system built on the ring-based gantry has the tight machine tolerances required for radiosurgery...
December 15, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29249566/evaluation-of-mlc-leaf-transmission-on-imrt-treatment-plan-quality-of-patients-with-advanced-lung-cancer
#8
Jiayun Chen, Guishan Fu, Minghui Li, Yixin Song, Jianrong Dai, Junjie Miao, Zhiqiang Liu, Yexiong Li
The purpose of this paper was to evaluate the impact of leaf treatment of multileaf collimator (MLC) in plan quality of intensity-modulated radiotherapy (IMRT) of patients with advanced lung cancer. Five MLCs with different leaf transmissions (0.01%, 0.5%, 1.2%, 1.8%, and 3%) were configured for an accelerator in a treatment planning system. Correspondingly, 5 treatment plans with the same optimization setting were created and evaluated quantitatively for each patient (11 patients total) who was diagnosed with advanced lung cancer...
December 14, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29233610/a-dosimetrist-s-sarcoma-journey
#9
LETTER
Christopher J Moore
No abstract text is available yet for this article.
December 9, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29223303/influence-of-body-habitus-on-dose-parameters-of-nodal-levels-iii-to-iv-irradiation-for-breast-cancer-comparison-of-3-techniques
#10
Sebastia Sabater, Marina Gascon, Manuel Gutierrez-Perez, Roberto Berenguer, Ellen M Donovan, Emma J Harris, Meritxell Arenas
This study aimed to investigate the effect of body habitus on supraclavicular (SC) dose-volume histogram (DVH) parameters among breast cancer patients according to 3 different techniques. Three SC irradiation plans were generated for 24 postoperative breast cancer patients: (1) direct antero-posterior field only (1fieldP), with dose prescribed to a 3-cm depth; (2) 3-cm depth plan (3cmP) using an antero-posterior field plus a posterior boost with the dose prescription defined to 3 cm; and (3) optimized plan (OptP) similar to 3cmP, with dose prescribed depending on the anatomy...
December 6, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29223302/modeling-the-target-dose-fall-off-in-imrt-and-vmat-planning-techniques-for-cervical-sbrt
#11
A Brito Delgado, D Cohen, T Y Eng, D N Stanley, Z Shi, M Charlton, A N Gutiérrez
There has been growing interest in the use of stereotactic body radiotherapy (SBRT) technique for the treatment of cervical cancer. The purpose of this study was to characterize dose distributions as well as model the target dose fall-off for intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) delivery techniques using 6 and 10 MV photon beam energies. Fifteen (n = 15) patients with non-bulky cervical tumors were planned in Pinnacle3 with a Varian Novalis Tx (HD120 MLC) using 6 and 10 MV photons with the following techniques: (1) IMRT with 10 non-coplanar beams (2) dual, coplanar 358° VMAT arcs (4° spacing), and (3) triple, non-coplanar VMAT arcs...
December 6, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29217331/dosimetric-impact-of-translational-and-rotational-setup-errors-for-spine-stereotactic-body-radiotherapy-a-phantom-study
#12
Makoto Sasaki, Mitsuhiro Nakamura, Nobutaka Mukumoto, Manabu Nakata, Masahiro Hiraoka
This study aimed to investigate experimentally the effect of translational and rotational setup errors on 3-dimensional dose distributions by using the gamma index and dose volumetric indices for spine stereotactic body radiotherapy. Treatment plans were designed in accordance with the Radiation Therapy Oncology Group (RTOG) 0631 protocol. Measurements were taken using a Delta4 phantom (ScandiDos, Uppsala, Sweden). Setup errors were generated using the HexaMotion 6D moving platform (ScandiDos). Dose distributions in the presence of setup errors were evaluated, according to the γ passing rate with the 3% and 2 mm criteria (γ3%/2 mm) and dose volumetric indices (D90 for the target volume and D2 for the spinal cord), using the Delta4 device (ScandiDos)...
December 4, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29203087/rebuttal-to-the-letter-to-the-editor-by-siamak-sabour-meddos-d-17-00095
#13
LETTER
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29198527/effects-of-multiple-breath-hold-reproducibility-on-treatment-localization-and-dosimetric-accuracy-in-radiotherapy-of-left-sided-breast-cancer-methodology-and-statistical-issues-in-reproducibility-and-accuracy
#14
LETTER
Siamak Sabour
No abstract text is available yet for this article.
December 1, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29198390/comparison-between-dvh-based-doses-and-icru-point-based-doses-to-the-rectum-and-the-bladder-using-ct-based-high-dose-rate-brachytherapy-to-the-cervix
#15
Ramya Rangarajan, Saravanan Subramanian, Kalyani Gopalakrishnan
Traditionally, doses to the bladder and the rectum were quantified using the bladder and rectal reference points defined by the International Commission on Radiation Units and Measurements (ICRU) in Report No. 38. In this study, we compared the 0.1-, 1.0-, 2.0-cc doses to the bladder and the rectum with the corresponding ICRU point doses using computed tomography (CT)-based planning in the intracavitary brachytherapy of carcinoma of the cervix. CT datasets of 136 consecutive intracavitary brachytherapy insertions between January and May 2015 were analyzed...
November 29, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29198389/cumulative-dose-of-radiation-therapy-of-hepatocellular-carcinoma-patients-and-its-deterministic-relation-to-radiation-induced-liver-disease
#16
Pu Huang, Gang Yu, Daniel S Kapp, Xue-Feng Bian, Chang-Sheng Ma, Hong-Sheng Li, Jin-Hu Chen, Yue-Qiang Liang, Yang Zhang, Shao-Hua Qin, Yao-Qin Xie, Yong Yang, Yong Yin, Lei Xing, Deng-Wang Li
This study aimed to investigate the relationship between dose and radiation-induced liver disease (RILD) in patients with hepatocellular carcinoma (HCC) receiving 3-dimensional conformal radiotherapy (3DCRT). Twenty-three patients with HCC who received conventional fractionated 3DCRT, including 7 who were diagnosed with classic RILD, were enrolled in this retrospective investigation. Cone-beam computed tomography (CBCT) scans were acquired at the time of treatment for each patient. The beams from each patient's treatment plan were applied to each pretreatment CBCT (the modified CBCT or mCBCT) to construct the delivered dose distribution of the day considering inter-treatment anatomy changes...
November 29, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29191470/optimal-beam-margins-in-linac-based-vmat-stereotactic-ablative-body-radiotherapy-a-pareto-front-analysis-for-liver-metastases
#17
Savino Cilla, Anna Ianiro, Francesco Deodato, Gabriella Macchia, Cinzia Digesù, Vincenzo Valentini, Alessio G Morganti
We explored the Pareto fronts mathematical strategy to determine the optimal block margin and prescription isodose for stereotactic body radiotherapy (SBRT) treatments of liver metastases using the volumetric-modulated arc therapy (VMAT) technique. Three targets (planning target volumes [PTVs] = 20, 55, and 101 cc) were selected. A single fraction dose of 26 Gy was prescribed (prescription dose [PD]). VMAT plans were generated for 3 different beam energies. Pareto fronts based on (1) different multileaf collimator (MLC) block margin around PTV and (2) different prescription isodose lines (IDL) were produced...
November 27, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29174796/knowledge-based-treatment-planning-and-its-potential-role-in-the-transition-between-treatment-planning-systems
#18
Kathryn Masi, Paul Archer, William Jackson, Yilun Sun, Matthew Schipper, Daniel Hamstra, Martha Matuszak
Commissioning a new treatment planning system (TPS) involves many time-consuming tasks. We investigated the role that knowledge-based planning (KBP) can play in aiding a clinic's transition to a new TPS. Sixty clinically treated prostate/prostate bed intensity-modulated radiation therapy (IMRT) plans were exported from an in-house TPS and were used to create a KBP model in a newly implemented commercial application. To determine the benefit that KBP may have in a TPS transition, the model was tested on 2 groups of patients...
November 22, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29110926/study-for-reducing-lung-dose-of-upper-thoracic-esophageal-cancer-radiotherapy-by-auto-planning-volumetric-modulated-arc-therapy-vs-intensity-modulated-radiation-therapy
#19
Hua Chen, Hao Wang, Hengle Gu, Yan Shao, Xuwei Cai, Xiaolong Fu, Zhiyong Xu
This study aimed to investigate the dosimetric differences and lung sparing between volumetric-modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) in the treatment of upper thoracic esophageal cancer with T3N0M0 for preoperative radiotherapy by auto-planning (AP). Sixteen patient cases diagnosed with upper thoracic esophageal cancer T3N0M0 for preoperative radiotherapy were retrospectively studied, and 3 plans were generated for each patient: full arc VMAT AP plan with double arcs, partial arc VMAT AP plan with 6 partial arcs, and conventional IMRT AP plan...
October 27, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29110925/a-novel-imrt-planning-study-by-using-the-fixed-jaw-method-in-the-treatment-of-peripheral-lung-cancer-with-mediastinal-lymph-node-metastasis
#20
Hao Wang, Hua Chen, Hengle Gu, Yan Shao, Xuwei Cai, Xiaolong Fu, Zhiyong Xu
Intensity-modulated radiotherapy (IMRT) is an important technology in cancer radiotherapy. In the current planning system, such as in the Pinnacle(3) system, jaw positions are automatically set to cover all target volumes, and many medical centers in developing countries are not equipped with linear accelerators with a jaw tracing function. As solitary lesions are often located in patients, the resulting radiation leakage and transmission increase the dose exposure in surrounding critical organs, although blocked by multileaf collimator (MLC) leaves...
October 27, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
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