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Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists

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https://www.readbyqxmd.com/read/27919621/a-comparative-study-of-standard-intensity-modulated-radiotherapy-and-rapidarc-planning-techniques-for-ipsilateral-and-bilateral-head-and-neck-irradiation
#1
Jennifer Pursley, Antonio L Damato, Maria A Czerminska, Danielle N Margalit, David J Sher, Roy B Tishler
The purpose of this study was to investigate class solutions using RapidArc volumetric-modulated arc therapy (VMAT) planning for ipsilateral and bilateral head and neck (H&N) irradiation, and to compare dosimetric results with intensity-modulated radiotherapy (IMRT) plans. A total of 14 patients who received ipsilateral and 10 patients who received bilateral head and neck irradiation were retrospectively replanned with several volumetric-modulated arc therapy techniques. For ipsilateral neck irradiation, the volumetric-modulated arc therapy techniques included two 360° arcs, two 360° arcs with avoidance sectors around the contralateral parotid, two 260° or 270° arcs, and two 210° arcs...
December 2, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27839693/pencil-beam-scanning-proton-therapy-vs-rotational-arc-radiation-therapy-a-treatment-planning-comparison-for-postoperative-oropharyngeal-cancer
#2
Ontida Apinorasethkul, Maura Kirk, Kevin Teo, Samuel Swisher-McClure, John N Lukens, Alexander Lin
Patients diagnosed with head and neck cancer are traditionally treated with photon radiotherapy. Proton therapy is currently being used clinically and may potentially reduce treatment-related toxicities by minimizing the dose to normal organs in the treatment of postoperative oropharyngeal cancer. The finite range of protons has the potential to significantly reduce normal tissue toxicity compared to photon radiotherapy. Seven patients were planned with both proton and photon modalities. The planning goal for both modalities was achieving the prescribed dose to 95% of the planning target volume (PTV)...
November 7, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27765542/dosimetric-comparison-of-helical-tomotherapy-intensity-modulated-radiation-therapy-volumetric-modulated-arc-therapy-and-3-dimensional-conformal-therapy-for-the-treatment-of-t1n0-glottic-cancer
#3
Kemal Ekici, Eda K Pepele, Bahaddin Yaprak, Oztun Temelli, Aysun F Eraslan, Nadir Kucuk, Ayse Y Altınok, Pelin A Sut, Ozlem D Alpak, Cemil Colak, Alpaslan Mayadagli
Various radiotherapy planning methods for T1N0 laryngeal cancer have been proposed to decrease normal tissue toxicity. We compare helical tomotherapy (HT), linac-based intensity-modulated radiation therapy (IMRT), volumetric-modulated arc therapy (VMAT), and 3-D conformal radiotherapy (3D-CRT) techniques for T1N0 laryngeal cancer. Overall, 10 patients with T1N0 laryngeal cancer were selected and evaluated. Furthermore, 10 radiotherapy treatment plans have been created for all 10 patients, including HT, IMRT, VMAT, and 3D-CRT...
October 17, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27751618/bladder-radiotherapy-treatment-a-retrospective-comparison-of-3-dimensional-conformal-radiotherapy-intensity-modulated-radiation-therapy-and-volumetric-modulated-arc-therapy-plans
#4
Katia Pasciuti, Shrinivas Kuthpady, Anne Anderson, Bronagh Best, Saleem Waqar, Subhra Chowdhury
To examine tumor׳s and organ׳s response when different radiotherapy plan techniques are used. Ten patients with confirmed bladder tumors were first treated using 3-dimensional conformal radiotherapy (3DCRT) and subsequently the original plans were re-optimized using the intensity-modulated radiation treatment (IMRT) and volumetric-modulated arc therapy (VMAT)-techniques. Targets coverage in terms of conformity and homogeneity index, TCP, and organs׳ dose limits, including integral dose analysis were evaluated...
October 14, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27751617/single-fraction-flattening-filter-free-volumetric-modulated-arc-therapy-for-lung-cancer-dosimetric-results-and-comparison-with-flattened-beams-technique
#5
Sara Barbiero, Alexandra Rink, Fabrizio Matteucci, David Fedele, Fabiola Paiar, Francesco Pasqualetti, Michele Avanzo
PURPOSE: To report on single-fraction stereotactic body radiotherapy (RT) (SBRT) with flattening filter (FF)-free (FFF) volumetric modulated arc therapy (VMAT) for lung cancer and to compare dosimetric results with VMAT with FF. METHODS AND MATERIALS: Overall, 25 patients were treated with 6-MV FFF VMAT (Varian TrueBeam STx LINAC) to a prescribed dose of 24Gy in a single fraction. Treatment plans were recreated using FF VMAT. Dose-volume indices, monitor units (MU), and treatment times were compared between FFF and FF VMAT techniques...
October 14, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27745996/neurovascular-bundle-sparing-radiotherapy-for-prostate-cancer-using-mri-ct-registration-a-dosimetric-feasibility-study
#6
R J Cassidy, X Yang, T Liu, M Thomas, S G Nour, A B Jani
PURPOSE: Sexual dysfunction after radiotherapy for prostate cancer remains an important late adverse toxicity. The neurovascular bundles (NVB) that lie posterolaterally to the prostate are typically spared during prostatectomy, but in traditional radiotherapy planning they are not contoured as an organ-at-risk with dose constraints. Our goal was to determine the dosimetric feasibility of "NVB-sparing" prostate radiotherapy while still delivering adequate dose to the prostate. METHODS: Twenty-five consecutive patients with prostate cancer (with no extraprostatic disease on pelvic magnetic resonance imaging [MRI]) who that were treated with external beam radiotherapy, with the same primary planning target volume margins, to a dose of 79...
October 13, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27745995/implementation-of-a-volumetric-modulated-arc-therapy-treatment-planning-solution-for-kidney-and-adrenal-stereotactic-body-radiation-therapy
#7
Marcus Sonier, William Chu, Nafisha Lalani, Darby Erler, Patrick Cheung, Renee Korol
To develop a volumetric modulated arc therapy (VMAT) treatment planning solution in the treatment of primary renal cell carcinoma and oligometastatic adrenal lesions with stereotactic body radiation therapy. Single-arc VMAT plans (n = 5) were compared with clinically delivered step-and-shoot intensity-modulated radiotherapy (IMRT) with planning target volume coverage normalized between techniques. Target volume conformity, organ-at-risk (OAR) dose, treatment time, and monitor units were compared. A VMAT planning solution, created from a combination of arc settings and optimization constraints, auto-generated treatment plans in a single optimization...
October 13, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27692518/treatment-planning-strategy-for-whole-brain-radiotherapy-with-hippocampal-sparing-and-simultaneous-integrated-boost-for-multiple-brain-metastases-using-intensity-modulated-arc-therapy
#8
Damodar Pokhrel, Sumit Sood, Christopher McClinton, Xinglei Shen, Christopher Lominska, Habeeb Saleh, Rajeev Badkul, Hongyu Jiang, Melissa Mitchell, Fen Wang
PURPOSE: To retrospectively evaluate the accuracy, plan quality and efficiency of intensity-modulated arc therapy (IMAT) for hippocampal sparing whole-brain radiotherapy (HS-WBRT) with simultaneous integrated boost (SIB) in patients with multiple brain metastases (m-BM). MATERIALS AND METHODS: A total of 5 patients with m-BM were retrospectively replanned for HS-WBRT with SIB using IMAT treatment planning. The hippocampus was contoured on diagnostic T1-weighted magnetic resonance imaging (MRI) which had been fused with the planning CT image set...
September 27, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27633817/role-of-belly-board-device-in-the-age-of-intensity-modulated-radiotherapy-for-pelvic-irradiation
#9
Neil C Estabrook, Gregory K Bartlett, Julia J Compton, Higinia R Cardenes, Indra J Das
Small bowel dose often represents a limiting factor for radiation treatment of pelvic malignancies. To reduce small bowel toxicity, a belly board device (BBD) with a prone position is often recommended. Intensity modulated radiotherapy (IMRT) could reduce dose to small bowel based on the desired dose-volume constraints. We investigated the efficacy of BBD in conjunction with IMRT. A total of 11 consecutive patients with the diagnosis of rectal cancer, who were candidates for definitive therapy, were selected...
September 12, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27623737/dosimetric-comparison-of-lung-stereotactic-body-radiotherapy-treatment-plans-using-averaged-computed-tomography-and-end-exhalation-computed-tomography-images-evaluation-of-the-effect-of-different-dose-calculation-algorithms-and-prescription-methods
#10
Takamasa Mitsuyoshi, Mitsuhiro Nakamura, Yukinori Matsuo, Nami Ueki, Akira Nakamura, Yusuke Iizuka, Wambaka Ange Mampuya, Takashi Mizowaki, Masahiro Hiraoka
The purpose of this article is to quantitatively evaluate differences in dose distributions calculated using various computed tomography (CT) datasets, dose-calculation algorithms, and prescription methods in stereotactic body radiotherapy (SBRT) for patients with early-stage lung cancer. Data on 29 patients with early-stage lung cancer treated with SBRT were retrospectively analyzed. Averaged CT (Ave-CT) and expiratory CT (Ex-CT) images were reconstructed for each patient using 4-dimensional CT data. Dose distributions were initially calculated using the Ave-CT images and recalculated (in the same monitor units [MUs]) by employing Ex-CT images with the same beam arrangements...
September 10, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27623736/dosimetric-analysis-of-testicular-doses-in-prostate-intensity-modulated-and-volumetric-modulated-arc-radiation-therapy-at-different-energy-levels
#11
Cem Onal, Gungor Arslan, Yemliha Dolek, Esma Efe
The aim of this study is to evaluate the incidental testicular doses during prostate radiation therapy with intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc radiotherapy (VMAT) at different energies. Dosimetric data of 15 patients with intermediate-risk prostate cancer who were treated with radiotherapy were analyzed. The prescribed dose was 78Gy in 39 fractions. Dosimetric analysis compared testicular doses generated by 7-field intensity-modulated radiotherapy and volumetric-modulated arc radiotherapy with a single arc at 6, 10, and 15MV energy levels...
September 10, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27623735/the-comparison-of-5-field-conformal-radiotherapy-techniques-for-the-treatment-of-prostate-cancer-the-best-for-femoral-head-sparing
#12
Mahkameh Zare, Marzieh Lashkari, Reza Ghalehtaki, Arash Ghasemi, Hamidreza Dehghan Manshadi, Ali Mir, Somayeh Noorollahi, Mahboobeh Alamolhoda
External radiotherapy is a standard treatment procedure for localized prostate cancer. Given the relatively high long term survival treatment complications have been brought in center of attention. In this planning study, between 2012 and 2014, CT simulation data of 90 consecutive high-risk prostate cancer patients were collected. In the first phase, all were planned for whole pelvis irradiation up to 46Gy in 23 daily fractions. In the second phase, only the prostate gland was the target of radiation. Next, the subjects were divided randomly into three groups and each received a unique 5field conformal radiation plan including Plan A (Gantry angle: 0, 60, 120, 240, and 300), Plan B (Gantry angles: 0, 90, 120, 240, and 270) and Plan C (Gantry angles: 0, 60, 90, 270, and 300)...
September 10, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27623391/assessment-of-the-feasibility-of-using-transrectal-ultrasound-for-postimplant-dosimetry-in-low-dose-rate-prostate-brachytherapy
#13
Rhian Siân Davies, Teresa Perrett, Jane Powell, Jim Barber, Jacob Tanguay, Michael Button, Dennis Cochlin, Christian Smith, Jason Francis Lester
A study was performed to establish whether transrectal ultrasound (TRUS)-based postimplant dosimetry (PID) is both practically feasible and comparable to computed tomography (CT)-based PID, recommended in current published guidelines. In total, 22 patients treated consecutively at a single cancer center with low-dose-rate (LDR) brachytherapy for early-stage prostate cancer had a transrectal ultrasound performed immediately after implant (d0-TRUS) and computed tomography scan 30 days after implant (d30-CT). Postimplant dosimetry planning was performed on both image sets and the results were compared...
September 9, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27614790/is-a-single-isocenter-sufficient-for-volumetric-modulated-arc-therapy-radiosurgery-when-multiple-itracranial-metastases-are-spatially-dispersed
#14
Jay Morrison, Rodney Hood, Fang-Fang Yin, Joseph K Salama, John Kirkpatrick, Justus Adamson
Previous work demonstrated improved dosimetry of single isocenter volumetric modulated arc therapy (VMAT) of multiple intracranial targets when they are located ≤ 4cm from isocenter because of narrower multileaf collimators (MLCs). In follow-up, we sought to determine if decreasing isocenter-target distance (diso) by using 2 to 3 isocenters would improve dosimetry for spatially dispersed targets. We also investigated the effect of a maximum dose constraint during VMAT optimization, and the dosimetric effect of the number of VMAT arcs used for a larger number of targets (i...
September 7, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27592592/dose-planning-management-of-patients-undergoing-salvage-whole-brain-radiation-therapy-after-radiosurgery
#15
Cheng B Saw, Frank Battin, Janice McKeague, Meghan Haggerty, Madhava Baikadi, Christopher Peters
Dose or treatment planning management is necessary for the re-irradiation of intracranial relapses after focal irradiation, radiosurgery, or stereotactic radiotherapy. The current clinical guidelines for metastatic brain tumors are the use of focal irradiation if the patient presents with 4 lesions or less. Salvage treatments with the use of whole brain radiation therapy (WBRT) can then be used to limit disease progression if there is an intracranial relapse. However, salvage WBRT poses a number of challenges in dose planning to limit disease progression and preserve neurocognitive function...
September 1, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27554205/technical-solutions-to-reduce-mediastinal-irradiation-in-young-patients-undergoing-treatment-for-lymphomas-preliminary-experience
#16
Michaela Benassi, Luana Di Murro, Barbara Tolu, Elisabetta Ponti, Maria Daniela Falco, Carla Rossi, Paolo Bagalà, Daniela di Cristino, Alessandra Murgia, Sara Cicchetti, Claudia Bruni, Pasquale Morelli, Andrea Lancia, Riccardo Santoni
This study aims at optimizing treatment planning in young patients affected by lymphoma (Stage II to III) by using an inclined board (IB) that allows reducing doses to the organs at risk. We evaluated 19 young patients affected by stage I to III lymphomas, referred to our Department for consolidation radiotherapy (RT) treatment on the mediastinum. Patients underwent 2 planning computed tomography (CT) scans performed in different positions: flat standard position and inclined position. A direct comparison between the different treatment plans was carried out analyzing dosimetric parameters obtained from dose-volume histograms generated for each plan...
August 20, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27839589/anatomical-contouring-variability-in-thoracic-organs-at-risk
#17
Ross McCall, Grayden MacLennan, Matthew Taylor, Nishele Lenards, Benjamin E Nelms, Matthew Koshy, Jeffrey Lemons, Ashley Hunzeker
The purpose of this study was to determine whether contouring thoracic organs at risk was consistent among medical dosimetrists and to identify how trends in dosimetrist׳s education and experience affected contouring accuracy. Qualitative and quantitative methods were used to contextualize the raw data that were obtained. A total of 3 different computed tomography (CT) data sets were provided to medical dosimetrists (N = 13) across 5 different institutions. The medical dosimetrists were directed to contour the lungs, heart, spinal cord, and esophagus...
January 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27839588/hybrid-isocenter-technique-for-gamma-knife-perfexion-treatment-of-trigeminal-neuralgia
#18
Young-Bin Cho, Normand Laperriere, Mojgan Hodaie, Caroline Chung
Gamma-Knife (GK), Perfexion (PFX) has 8 sectors that can be blocked compared with the older model 4C, which has 201 independent source blocking options using plugs. This limits the ability of PFX to shape a single isocenter plan, such as trigeminal neuralgia. In this retrospective review and prospective re-planning comparison study of trigeminal neuralgia radiosurgery plans, a hybrid isocenter technique (HIT) is compared with single isocenter GK radiosurgery plans on 2 models (4C and PFX) dosimetric parameters...
January 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27545010/dosimetric-quality-accuracy-and-deliverability-of-modulated-radiotherapy-treatments-for-spinal-metastases
#19
Tanya Kairn, Daniel Papworth, Scott B Crowe, Jennifer Anderson, David R H Christie
Cancer often metastasizes to the vertebra, and such metastases can be treated successfully using simple, static posterior or opposed-pair radiation fields. However, in some cases, including when re-irradiation is required, spinal cord avoidance becomes necessary and more complex treatment plans must be used. This study evaluated 16 sample intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) treatment plans designed to treat 6 typical vertebral and paraspinal volumes using a standard prescription, with the aim of investigating the advantages and limitations of these treatment techniques and providing recommendations for their optimal use in vertebral treatments...
2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27545009/radiation-therapy-for-breast-cancer-literature-review
#20
REVIEW
Karunakaran Balaji, Balaji Subramanian, Poonam Yadav, Chandrasekaran Anu Radha, Velayudham Ramasubramanian
Concave shape with variable size target volume makes treatment planning for the breast/chest wall a challenge. Conventional techniques used for the breast/chest wall cancer treatment provided better sparing of organs at risk (OARs), with poor conformity and uniformity to the target volume. Advanced technologies such as intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) improve the target coverage at the cost of higher low dose volumes to OARs. Novel hybrid techniques present promising results in breast/chest wall irradiation in terms of target coverage as well as OARs sparing...
2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
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