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Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists

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https://www.readbyqxmd.com/read/30236506/use-of-electronic-portal-images-to-evaluate-setup-error-and-intra-fraction-motion-during-free-breathing-breast-imrt-treatment
#1
Jing-Min Hwang, Jing-Yin Hung, Yi-Han Tseng, You-Kang Chang, Yu-Nong Wang, Chiou-Shiung Chang
Before delivering of intensity-modulated radiotherapy, kilo-voltage image-guidance radiotherapy is widely used in setup error correction and monitoring intra-fraction motion effectively. Accordingly, this study proposes and tests an image integration technique for observing intra-fraction motion during beam delivery, with the wider objective of reducing both image-guidance time and the dose delivered to normal breast tissue. The study sample comprised 33 female patients with breast cancer, and 241 sets of portal images acquired using a VARIAN aSi-1000 electronic portal imaging device...
September 17, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30197035/varian-halcyon-dosimetric-comparison-for-multiarc-vmat-prostate-and-head-and-neck-cancers
#2
LETTER
Catalina Riley, Christopher Cox, Sasha Graham, Holly Havran, Bethany Kramer, Tucker Netherton, Christine Peterson, Tyler Williamson, Laurence Court
The Varian Halcyon linear accelerator is designed for faster treatment time and fewer treatment errors than conventional linear accelerators. Its increased gantry speed (4 rpm), dose rate (800 MU/min), and leaf speed (5 cm/s) reduce treatment time. The 2 multileaf collimator banks of 1 cm leaf width could cause planning difficulties, but utilizing many arcs could address this challenge. While 3 or more arcs are often avoided due to the increased treatment time, the Halcyon can deliver 5 arcs in under 3 minutes...
September 6, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30193991/imrt-planning-parameter-optimization-for-spine-stereotactic-radiosurgery
#3
LETTER
Gabriel B Ayala, Kieu A Doan, Hie Ji Ko, Peter K Park, Edwin D Santiago, Shirly J Kuruvila, Tina M Briere, Zhifei Wen
Spine stereotactic radiosurgery (SSRS) is a noninvasive treatment for metastatic spine lesions. MD Anderson Cancer Center reports a quality assurance (QA) failure rate approaching 15% for SSRS cases, which we hypothesized is due to difficulties in accurately calculating dose resulting from a large number of small-area segments. Clinical plans typically use 9 beams with an average of 10 segments per beam and minimum segment area of 2 to 3 cm2 . The purpose of this study was to identify a set of intensity-modulated radiation therapy (IMRT) planning parameters that attempts to optimize the balance among QA passing rate, plan quality, dose calculation accuracy, and delivery time for SSRS plans...
September 4, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30170990/dosimetric-evaluation-of-right-coronary-artery-in-radiotherapy-for-breast-cancer
#4
Ayşe Altınok, Orbay Askeroğlu, Mine Doyuran, Mustafa Çağlar, Emir Cantürk, Cengiz Erol, Nuran Beşe
Comparison with control groups of untreated patients suggests that right-breast-cancer patients who receive radiotherapy have a higher rate of heart disease. Dose constraint for heart has been established to minimize radiotherapy-induced cardiotoxicity during left breast cancer treatment. Additionally, it is suggested to minimize the dosage on left anterior descending (LAD) artery. Right coronary artery (RCA), is the second largest artery, after left main coronary artery, supplying the heart. A dose evaluation study is not present for RCA; the proximal part of which is included in the irradiation field during breast cancer treatment of right breast...
August 28, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30166077/the-implementation-of-rapidplan-in-predicting-deep-inspiration-breath-hold-candidates-with-left-sided-breast-cancer
#5
Aubrie Rice, Ian Zoller, Kevin Kocos, Dannyl Weller, Dominic DiCostanzo, Ashley Hunzeker, Nishele Lenards
The aim of this study is to determine if RapidPlan (RP) can be used as a prediction method to determine which left-sided supine breast cancer patients would benefit from the deep inspiration breath-hold (DIBH) technique. An RP model database was created with 72 clinically approved 3D conformal radiation therapy (3D-CRT) treatment plans. This model was validated by introducing 10 new patient data sets, creating RP-generated plans and comparing the clinically approved plan for the corresponding patient. The prediction ability of the model was then tested on the free-breathing (FB) scans of patients with clinically approved DIBH plans totaling 29 patients and results were then compared to the FB clinical plan attempts...
August 28, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30153966/accuracy-and-efficiency-of-graphics-processing-unit-gpu-based-acuros-xb-dose-calculation-within-the-varian-eclipse-treatment-planning-system
#6
Trent Aland, Anthony Walsh, Mark Jones, Angelina Piccini, Aimee Devlin
To evaluate, in terms of dosimetric accuracy and calculation efficiency, the implementation of a graphic processing unit (GPU)-based Acuros XB dose calculation engine within version 15.5 of the Varian Eclipse treatment planning system. Initial phantom based calculations and a range of 101 clinical cases were analyzed on a dedicated test system. Dosimetric differences, based on dose-volume histrogram parameters and plan comparison, were compared between central processing unit (CPU) and GPU based calculation...
August 25, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30153965/dose-uncertainty-from-calculation-grid-resolution-and-its-alignment-with-mlc
#7
Jinkoo Kim, Archie Chu, Zhigang Xu
The aims are (1) to present a clinical brain case where the dose distribution calculated at 2.5-mm grid resolution was significantly different from that of 1.0 mm with Varian HD120 multileaf collimator (MLC; 2.5-mm central leaf width), and (2) to present our analysis results to better understand the influence of dose calculation grid resolution and its spatial alignment with MLC. A simulation using a static MLC pattern with 10 open strips was conducted to demonstrate the possibility that the characteristics of MLC dose profiles can be completely hidden...
August 25, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30135024/a-robust-volumetric-arc-therapy-planning-approach-for-breast-cancer-involving-the-axillary-nodes
#8
LETTER
Gijs J van der Veen, Tomas Janssen, Amber Duijn, Simon van Kranen, Rob J de Graaf, Geert Wortel, Terry G Wiersma, Eugène Damen
We quantify the robustness of a proposed volumetric-modulated arc therapy (VMAT) planning and treatment technique for radiotherapy of breast cancer involving the axillary nodes. The proposed VMAT technique is expected to be more robust to breast shape changes and setup errors, yet maintain the improved conformity of VMAT compared to our current standard technique that uses tangential intensity-modulated radiation therapy (IMRT) fields. Treatment plans were created for 10 patients. To account for anatomical variation, planning was carried out on a computed tomography (CT) with an expanded breast, followed by segment weight optimization (SWO) on the original planning CT (VMAT + SWO)...
August 19, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30119882/avoidance-sectors-to-reduce-dosimetric-impact-of-an-irreproducible-pannus-on-setup-uncertainty-in-prostate-sbrt-vmat-a-case-study
#9
Emily Hubley, Gaurav Shukla, Yelena Vakhnenko, Robert B Den, Amy S Harrison
This work investigates whether the use of an avoidance sector in a two-arc volumetric modulated arc therapy (VMAT) prostate stereotactic body radiotherapy (SBRT) plan reduces dosimetric variations due to an irreproducible pannus. A morbidly obese patient with favorable-risk prostate cancer elected treatment with SBRT. The patient was treated with the avoidance arcs across the pannus to eliminate reproducibility issues created by daily pannus variability in set up. For post-treatment assessment, the case was planned using Varian Eclipse™ treatment planning system (TPS) with two VMAT arcs with and without 100° avoidance sectors across the pannus...
August 14, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30115539/mri-based-treatment-planning-for-brain-stereotactic-radiosurgery-dosimetric-validation-of-a-learning-based-pseudo-ct-generation-method
#10
Tonghe Wang, Nivedh Manohar, Yang Lei, Anees Dhabaan, Hui-Kuo Shu, Tian Liu, Walter J Curran, Xiaofeng Yang
Magnetic resonance imaging (MRI)-only radiotherapy treatment planning is attractive since MRI provides superior soft tissue contrast without ionizing radiation compared with computed tomography (CT). However, it requires the generation of pseudo CT from MRI images for patient setup and dose calculation. Our machine-learning-based method to generate pseudo CT images has been shown to provide pseudo CT images with excellent image quality, while its dose calculation accuracy remains an open question. In this study, we aim to investigate the accuracy of dose calculation in brain frameless stereotactic radiosurgery (SRS) using pseudo CT images which are generated from MRI images using the machine learning-based method developed by our group...
August 14, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30097226/the-dosimetric-differences-in-calculating-lung-sbrt-plans-on-different-image-data-sets-comparison-of-the-free-breathing-scan-to-both-the-average-intensity-projection-scan-and-to-the-sum-of-calculations-on-each-respiratory-phase-of-the-4dct-scan
#11
LETTER
Francesco Gaetani Liseo, Tim Lautenschlaeger, Marvene Ewing, Mark Langer
The purpose of this study is to evaluate the dosimetric differences to the lung internal target volume (ITV) in stereotactic body radiation therapy (SBRT) when calculated on the free breathing (FB) scan in comparison to calculations on the average intensity projection (AIP) scan as well as the sum of dose calculated on each of the treated respiratory phases. The clinical treatment plan data for 16 SBRT lung patients were retrospectively chosen for this study, 5 of which were 30% to 70% respiratory phase gated...
August 7, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/30078605/dosimetric-comparison-of-deep-inspiration-breath-hold-and-free-breathing-treatment-delivery-techniques-for-left-sided-breast-cancer-using-3d-surface-tracking
#12
Winston Vuong, Rupen Garg, Daniel J Bourgeois, Suhong Yu, Varun Sehgal, Parima Daroui
INTRODUCTION: While radiation therapy has been shown to increase local control and overall survival for breast cancer, late cardiac toxicity remains a concern. Morbidity and mortality have been shown to increase proportionally to the mean heart dose. Deep inspiration breath-hold (DIBH) can reduce heart dose compared to free-breathing (FB) by increasing the heart-to-chest wall distance, especially in left-sided breast cancer. We present our clinical experience with DIBH in left breast and chest-wall irradiation using 3D optical surface tracking...
August 2, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29753335/external-beam-planning-module-of-eclipse-for-external-beam-radiation-therapy
#13
REVIEW
Cheng B Saw, SiCong Li, Frank Battin, Janice McKeague, Christopher A Peters
Eclipse is a 3-dimensional (3D) treatment planning system for radiation therapy offered by Varian Medical Systems, Inc. The system has the network connectivity for the electronic transfer of image datasets and digital data communication among different equipment. The scope of this project for this special issue of Medical Dosimetry on 3D treatment planning systems is the assessment of planning tools in the external beam planning module of Eclipse to generate optimized treatment plans for patients undergoing external beam radiation therapy...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29753334/3d-treatment-planning-system-varian-eclipse-for-proton-therapy-planning
#14
REVIEW
Narayan Sahoo, Falk Poenisch, Xiaodong Zhang, Yupeng Li, MingFu Lii, Heng Li, Archana S Gautam, Richard Wu, Michael Gillin, Xiaorong R Zhu
The capabilities of the Eclipse treatment planning system (TPS) (Varian Medical Systems, Palo Alto, CA) for proton therapy treatment planning are described. Various steps involved in the planning process to produce a 3-dimensional (3D) dose distribution both for the passive scattering and pencil beam scanning proton beam therapy are outlined. Mitigation of range and setup uncertainties through robust optimization is discussed. Use of verification plans for patient treatment field dosimetry quality assurance (QA) is presented...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29753333/3d-treatment-planning-systems
#15
REVIEW
Cheng B Saw, Sicong Li
Three-dimensional (3D) treatment planning systems have evolved and become crucial components of modern radiation therapy. The systems are computer-aided designing or planning softwares that speed up the treatment planning processes to arrive at the best dose plans for the patients undergoing radiation therapy. Furthermore, the systems provide new technology to solve problems that would not have been considered without the use of computers such as conformal radiation therapy (CRT), intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT)...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29656889/3-d-treatment-planning-system-leksell-gamma-knife-treatment-planning-system
#16
REVIEW
Fanqing Guo
Leksell Gamma Plan (LGP), the treatment planning system for the Leksell Gamma Knife (LGK) stereotactic radiosurgery, has evolved from the primitive KULA system to the present-day powerful version of image-guided stereotactic radiosurgery. Through many years of development, LGP has improved on its dose calculation accuracy, speed, and user interface. This allows more accurate irradiation of the target while sparing the nearby normal tissues and critical structures better.
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29650302/raystation-external-beam-treatment-planning-system
#17
Dayna Bodensteiner
RaySearch Laboratories is a world leader in the field of advanced software and creator of the RayStation treatment planning system for radiation therapy. The aim with RayStation is to deliver an unmatched user experience and leading functionality. Unique features described here include multiatlas based autosegmentation for contouring, deformable registration with 2 different algorithms, multicriteria optimization, Plan Explorer, fallback planning, ultrafast computation speed, and 4-dimensional (4D) adaptive radiation therapy...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29609845/evolution-of-brachytherapy-treatment-planning-to-deterministic-radiation-transport-for-calculation-of-cardiac-dose
#18
REVIEW
Peter A Sandwall, Yuntao Feng, Michael Platt, Michael Lamba, Sudha Mahalingam
Brachytherapy was among the first methods of radiotherapy and has steadily continued to evolve. Here we present a brief review of the progression of dose calculation methods in brachytherapy to the current state-of-the art computerized methods for heterogeneity correction. We further review the origin and development of the BrachyVision (Varian Medical Systems, Inc., Palo Alto, CA) treatment planning system and evaluate dosimetric results from 12 patients implanted with the strut-assisted volumetric implant (SAVI) applicator (Cianna Medical, Aliso Viejo, CA) for accelerated partial breast irradiation (APBI)...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29605528/cyberknife-stereotactic-radiosurgery-and-radiation-therapy-treatment-planning-system
#19
REVIEW
Chuxiong Ding, Cheng B Saw, Robert D Timmerman
CyberKnife is an image-guided stereotactical dose delivery system designed for both focal irradiation and radiation therapy (SRT). Focal irradiation refers the use of many small beams to deliver highly focus dose to a small target region in a few fractions. The system consists of a 6-MV linac mounted to a robotic arm, coupled with a digital x-ray imaging system. The radiation dose is delivered using many beams oriented at a number of defined or nodal positions around the patients. The CyberKnife can be used for both intracranial and extracranial treaments unlike the Gamma Knife which is limited to intracranial cases...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29598924/oncentra-brachytherapy-planning-system
#20
REVIEW
Jack Yang
In modern cancer management, treatment planning has progressed as a contemporary tool with all the advances in computing power in recent years. One of the advanced planning tools uses 3-dimensional (3D) data sets for accurate dose distributions in patient prescription. Among these planning processes, brachytherapy has been a very important part of a successful cancer management program, offering clinical benefits with specific or combined treatments with external beam therapy. In this chapter, we mainly discussed the Elekta Oncentra planning system, which is the main treatment planning tool for high-dose rate (HDR) modality in our facility and in many other facilities in the United States...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
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