journal
MENU ▼
Read by QxMD icon Read
search

Respiratory Medicine

journal
https://www.readbyqxmd.com/read/28622920/post-9-11-sarcoidosis-in-wtc-exposed-firefighters-and-emergency-medical-service-workers
#1
Mayris P Webber, Jennifer Yip, Rachel Zeig-Owens, William Moir, Patompong Ungprasert, Cynthia S Crowson, Charles B Hall, Nadia Jaber, Michael D Weiden, Eric L Matteson, David J Prezant
INTRODUCTION: The World Trade Center (WTC) disaster released a huge quantity and variety of toxicants into the environment. To-date, studies from each of the three major cohorts of WTC-exposed workers have suggested "greater than expected" numbers of post-9/11 cases in some workers. We undertook this study to estimate the incidence of post-9/11 sarcoidosis in ∼13,000 male firefighters and EMS workers enrolled in The Fire Department of the City of New York (FDNY) WTC Health Program; to compare FDNY incidence to rates from unexposed, demographically similar men in the Rochester Epidemiology Project (REP); and, to examine rates by level of WTC exposure...
June 7, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28566230/efficacy-and-safety-of-indacaterol-in-patients-with-chronic-obstructive-pulmonary-disease-aged-over-65-years-a-pooled-analysis
#2
Pierre-Olivier Girodet, Jean-Yves Jasnot, Vincent Le Gros, Laurent Decuypère, Weihua Cao, Gilles Devouassoux
BACKGROUND: Although the prevalence of chronic obstructive pulmonary disease (COPD) increases with age, no specific therapeutic approaches are available till date for the elderly population. AIM: To assess the efficacy and safety of once-daily indacaterol 150 and 300 μg in elderly patients with moderate to severe COPD. METHODS: Data were pooled from 11 randomized, double-blind, placebo- and active-controlled studies (8445 patients with COPD)...
May 24, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28476471/elevated-levels-of-circulating-exosome-in-copd-patients-are-associated-with-systemic-inflammation
#3
Dino B A Tan, Jesse Armitage, Teck-Hui Teo, Nathanael E Ong, Heewoong Shin, Yuben P Moodley
Chronic obstructive pulmonary disease (COPD) is characterized by progressive pulmonary and systemic inflammation. Acute exacerbations of COPD (AECOPD) are associated with acute inflammation and infections and increase the rates of morbidity and mortality. Currently, neither the aetiology nor pathogenesis of AECOPD are entirely understood. Exosomes have been reported to regulate immunity and inflammation via specific intercellular communications through an array of macromolecules (e.g. microRNA and proteins) contained within these microvesicles...
April 26, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28476472/adverse-outcomes-associated-with-pulmonary-hypertension-in-chronic-obstructive-pulmonary-disease-after-bilateral-lung-transplantation
#4
Don Hayes, Dmitry Tumin, Maria M Budev, Joseph D Tobias, Roy C St John, Jasleen Kukreja
BACKGROUND: The impact of pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) on survival after lung transplantation (LTx) is not known. MATERIAL AND METHODS: First-time adult LTx recipients with COPD transplanted between May 2005 and September 2013 were identified in the United Network for Organ Sharing Registry database, and tracked from transplant date until death or censoring. Right heart catheterization (RHC) measurements at time of wait listing were used to predict all-cause mortality after LTx, with multivariable analyses stratified by transplant type...
April 22, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28461123/the-long-term-outcome-of-interstitial-lung-disease-with-anti-aminoacyl-trna-synthetase-antibodies
#5
Kiminobu Tanizawa, Tomohiro Handa, Ran Nakashima, Takeshi Kubo, Yuji Hosono, Kizuku Watanabe, Kensaku Aihara, Kohei Ikezoe, Akihiko Sokai, Yoshinari Nakatsuka, Yoshio Taguchi, Kazuhiro Hatta, Satoshi Noma, Yoichiro Kobashi, Akihiko Yoshizawa, Toru Oga, Toyohiro Hirai, Kazuo Chin, Sonoko Nagai, Takateru Izumi, Tsuneyo Mimori, Michiaki Mishima
RATIONALE: Anti-aminoacyl transfer RNA synthetase antibodies (anti-ARS) are a group of myositis-specific autoantibodies that are detected in the sera of patients with polymyositis and dermatomyositis (PM/DM) and also in those of patients with idiopathic interstitial pneumonias without any connective tissue disease (CTD), including PM/DM. Although we reported the clinical characteristics of interstitial lung disease with anti-ARS antibodies (ARS-ILD) with and without PM/DM, the long-term prognosis of ARS-ILD remains undetermined...
April 15, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610675/effect-of-a-single-exacerbation-on-decline-in-lung-function-in-copd
#6
David M G Halpin, Marc Decramer, Bartolome R Celli, Achim Mueller, Norbert Metzdorf, Donald P Tashkin
BACKGROUND: COPD exacerbations are associated with accelerated lung function decline, but whether they are causal is unknown. We evaluated the effect of a single exacerbation on rate of lung function change using data from the 4-year Understanding Potential Long-term Impacts on Function with Tiotropium (UPLIFT(®)) trial. METHODS: Retrospective analysis of annual rates of decline in FEV1 and FVC before and after a single (and the only) moderate-to-severe exacerbation in patients during UPLIFT(®) (exacerbator subgroup), compared with changes between the first and second half of the study in a non-exacerbator subgroup...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610674/elevated-serum-d-dimer-level-is-associated-with-an-increased-risk-of-acute-exacerbation-in-interstitial-lung-disease
#7
Genta Ishikawa, Samuel O Acquah, Mary Salvatore, Maria L Padilla
BACKGROUND: Early recognition of patients with interstitial lung disease (ILD) who have an increased risk of developing acute exacerbation (AE) or preclinical AE may be clinically useful, since AE is associated with poor outcome and preventive measures would be of interest to ILD researchers. This study evaluated the relationship between elevated serum D-dimer level (≥0.4 mcg/mL) and subsequent AE or preclinical AE in patients with ILD. METHODS: This single-center, retrospective study was performed from October 2009 through September 2015 in patients with ILD who were ≥18 years old and had idiopathic pulmonary fibrosis, other idiopathic interstitial pneumonias, chronic hypersensitivity pneumonitis, ILD related to collagen tissue disease, or combined pulmonary fibrosis/emphysema...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610673/sit-to-stand-tests-for-copd-a-literature-review
#8
REVIEW
Trija Vaidya, Arnaud Chambellan, Claire de Bisschop
BACKGROUND: Sit-to-stand tests (STST) have recently been developed as easy-to-use field tests to evaluate exercise tolerance in COPD patients. As several modalities of the test exist, this review presents a synthesis of the advantages and limitations of these tools with the objective of helping health professionals to identify the STST modality most appropriate for their patients. METHOD: Seventeen original articles dealing with STST in COPD patients have been identified and analysed including eleven on 1min-STST and four other versions of the test (ranging from 5 to 10 repetitions and from 30 s to 3 min)...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610672/agoraphobic-avoidance-predicts-emotional-distress-and-increased-physical-concerns-in-chronic-obstructive-pulmonary-disease
#9
Pawel Holas, Jaroslaw Michałowski, Łukasz Gawęda, Joanna Domagała-Kulawik
BACKGROUND: Anxiety and panic attacks are more common in chronic obstructive pulmonary disease (COPD) than in the overall population. Individuals with panic attacks often attempt to avoid situations perceived as at risk of eliciting bodily sensations such as dyspnea, which paradoxically may lead to anxiety-related responsivity. Although there is some evidence that COPD individuals restrict their participation in various life activities because they fear that these may trigger breathlessness, little is known about agoraphobic avoidance and its impact on cognitions and emotional distress in this population...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610671/pulmonary-manifestations-of-urothelial-carcinoma-of-the-bladder
#10
REVIEW
Abhinav Agrawal, Sonu Sahni, Abhinav K Vulisha, Rammohan Gumpeni, Rakesh Shah, Arunabh Talwar
Urothelial carcinoma (Transitional cell carcinoma) of the bladder is the pre-dominant histological type of bladder cancer in the United States and Europe. Patients with bladder cancer usually present with painless hematuria. The diagnosis is often delayed, as the symptoms are similar to various other benign conditions such as urinary tract infection, prostatitis or renal calculi. In some patients, the metastatic lesions will cause the initial presenting symptoms. We conducted a MedLine/PubMED search identifying all relevant articles with "pulmonary manifestations", "urothelial bladder cancer", "manifestations of bladder cancer" or a combination of these terms in the title...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610670/lung-ultrasound-as-a-diagnostic-tool-for-radiographically-confirmed-pneumonia-in-low-resource-settings
#11
Laura E Ellington, Robert H Gilman, Miguel A Chavez, Farhan Pervaiz, Julio Marin-Concha, Patricia Compen-Chang, Stefan Riedel, Shalim J Rodriguez, Charlotte Gaydos, Justin Hardick, James M Tielsch, Mark Steinhoff, Jane Benson, Evelyn A May, Dante Figueroa-Quintanilla, William Checkley
BACKGROUND: Pneumonia is a leading cause of morbidity and mortality in children worldwide; however, its diagnosis can be challenging, especially in settings where skilled clinicians or standard imaging are unavailable. We sought to determine the diagnostic accuracy of lung ultrasound when compared to radiographically-confirmed clinical pediatric pneumonia. METHODS: Between January 2012 and September 2013, we consecutively enrolled children aged 2-59 months with primary respiratory complaints at the outpatient clinics, emergency department, and inpatient wards of the Instituto Nacional de Salud del Niño in Lima, Peru...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610669/riociguat-for-pulmonary-arterial-hypertension-and-chronic-thromboembolic-pulmonary-hypertension-results-from-a-phase-ii-long-term-extension-study
#12
Michael Halank, Marius M Hoeper, Hossein-Ardeschir Ghofrani, F Joachim Meyer, Gerd Stähler, Jürgen Behr, Ralf Ewert, Monique Fletcher, Pablo Colorado, Sylvia Nikkho, Friedrich Grimminger
BACKGROUND: Riociguat was well tolerated and improved exercise and functional capacity in patients with pulmonary arterial hypertension (PAH) and inoperable chronic thromboembolic pulmonary hypertension (CTEPH) in a 12-week Phase II trial. We present final data from the long-term extension phase of this study. METHODS: During this multicenter, open-label, uncontrolled long-term extension study, riociguat dose could be changed at the physician's discretion (range 0...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610668/evaluation-of-the-psychometric-properties-of-the-st-george-s-respiratory-questionnaire-in-patients-with-severe-asthma
#13
Linda M Nelsen, Margaret Vernon, Hector Ortega, Sarah M Cockle, Steven W Yancey, Guy Brusselle, Frank C Albers, Paul W Jones
PURPOSE: Limited data exist on the quantitative validity of the St George's Respiratory Questionnaire (SGRQ) in asthma populations. This study evaluated the psychometric properties of the SGRQ in patients with severe asthma. METHODS: This was a post-hoc analysis of pooled data from MENSA (N = 576; NCT01691508) and SIRIUS (N = 135; NCT01691521), two randomized, placebo controlled trials of mepolizumab in patients with severe asthma. Patients completed the SGRQ at Baseline and Exit (MENSA Week 32; SIRIUS Week 24)...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610667/why-choose-tiotropium-for-my-patient-a-comprehensive-review-of-actions-and-outcomes-versus-other-bronchodilators
#14
REVIEW
David M Halpin, Alan G Kaplan, Richard K Russell
PURPOSE: Chronic obstructive pulmonary disease (COPD) and asthma are leading causes of morbidity and mortality. This narrative review provides an appraisal of the pharmacological and clinical characteristics of tiotropium in COPD and asthma, and examines how these compare with other long-acting bronchodilators. The evidence base is placed into context by relating it to factors affecting clinicians' choice of therapy. MAIN FINDINGS: Desirable attributes of a long-acting muscarinic antagonist (LAMA) maintenance therapy include effective pharmacological bronchodilation, improved lung function, exacerbation efficacy, and positive effects on symptom control, exercise capacity and quality of life across a broad patient population...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610666/informal-caregiving-in-copd-a-systematic-review-of-instruments-and-their-measurement-properties
#15
REVIEW
Joana Cruz, Alda Marques, Ana Machado, Sachi O'Hoski, Roger Goldstein, Dina Brooks
BACKGROUND: Increasing symptoms and activity restriction associated with COPD progression greatly impact on the lives of their informal caregivers, who play a vital role in maintaining their health. An understanding of this impact is important for clinicians to support caregivers and maintain a viable patient environment at home. This systematic review aimed to identify the instruments commonly used to assess informal caregiving in COPD and describe their measurement properties in this population...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28610665/anti-pseudomonas-aeruginosa-igg-antibodies-and-chronic-airway-infection-in-bronchiectasis
#16
Guillermo Suarez-Cuartin, Alex Smith, Hani Abo-Leyah, Ana Rodrigo-Troyano, Lidia Perea, Silvia Vidal, Vicente Plaza, Thomas C Fardon, Oriol Sibila, James D Chalmers
BACKGROUND: Identification of chronic Pseudomonas aeruginosa (PA) infection is important in the management of bronchiectasis, but requires repeated sputum sampling. We hypothesized that serum anti-PA IgG antibodies could diagnose chronic PA infection at a single visit. METHODS: Clinically stable bronchiectasis patients were studied prospectively. Chronic PA infection was defined as 2 or more positive sputum samples at least 3 months apart and/or failure to clear PA following eradication treatment...
July 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28502420/cardiopulmonary-exercise-testing-and-second-line-pulmonary-function-tests-to-detect-obstructive-pattern-in-symptomatic-smokers-with-borderline-spirometry
#17
Fabiano Di Marco, Silvia Terraneo, Sara Job, Rocco Francesco Rinaldo, Giuseppe Francesco Sferrazza Papa, Maria Adelaide Roggi, Pierachille Santus, Stefano Centanni
BACKGROUND: The need for additional research on symptomatic smokers with normal spirometry has been recently emphasized. Albeit not meeting criteria for Chronic obstructive pulmonary disease (COPD) diagnosis, symptomatic smokers may experience activity limitation, evidence of airway disease, and exacerbations. We, therefore, evaluated whether symptomatic smokers with borderline spirometry (post-bronchodilator FEV1/FVC ratio between 5th to 20th percentile of predicted values) have pulmonary function abnormalities at rest and ventilatory constraints during exercise...
June 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28502419/the-performance-of-the-gap-model-in-patients-with-rheumatoid-arthritis-associated-interstitial-lung-disease
#18
Julie Morisset, Eric Vittinghoff, Bo Young Lee, Roberto Tonelli, Xiaowen Hu, Brett M Elicker, Jay H Ryu, Kirk D Jones, Stefania Cerri, Andreina Manfredi, Marco Sebastiani, Andrew J Gross, Brett Ley, Paul J Wolters, Talmadge E King, Dong Soon Kim, Harold R Collard, Joyce S Lee
BACKGROUND: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is associated with significant morbidity and mortality. Similarities have been observed between patients with idiopathic pulmonary fibrosis (IPF) and the UIP (usual interstitial pneumonia) form of RA-ILD. The GAP (gender, age, physiology) model has been shown to predict mortality in patients with IPF, but its ability to predict mortality in RA-ILD is not known. METHODS: We identified 309 patients with RA-ILD at 4 academic centers with ongoing longitudinal cohorts of patients with ILD...
June 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28502418/a-multicenter-cross-sectional-observational-study-of-budesonide-formoterol-maintenance-and-reliever-therapy-in-real-world-settings
#19
Jiangtao Lin, Jing Li, Wencheng Yu, Yuejian Liu, Chuntao Liu, Ping Chen, Huijie He, Bei He, Shuang Liu, Xiangdong Zhou
BACKGROUND: To assess the level of asthma control achieved with budesonide/formoterol in Chinese patients with asthma, based on the Global Initiative for Asthma (GINA) definition and Asthma Control Test (ACT) score. METHODS: This multicenter, cross-sectional study (NCT01785901) evaluated asthma control levels in Chinese patients receiving physician-prescribed budesonide/formoterol treatment. Adults with a diagnosis of asthma ≥6 months and receiving budesonide/formoterol treatment ≥3 months before screening were consecutively enrolled...
June 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28502417/analysis-of-bronchial-biopsies-in-chronic-cough
#20
Patricia Macedo, Qingling Zhang, Junpei Saito, Zhike Liang, Lorrette Ffolkes, Andrew G Nicholson, Kian Fan Chung
BACKGROUND: Chronic cough is commonly associated with asthma, gastro-oesophageal reflux disease and postnasal drip, but in a significant proportion, no associated cause can be found. We determined whether examination of bronchial biopsies would be useful in determining the cause associated with chronic cough. METHODS: 100 consecutive patients referred to a specialist cough clinic underwent a systematic assessment including a fiberoptic bronchoscopy for bronchial biopsies...
June 2017: Respiratory Medicine
journal
journal
30133
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"