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Phytotherapy Research: PTR

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https://www.readbyqxmd.com/read/29266487/antiadhesion-activity-of-juniper-juniperus-communis-l-preparations-against-campylobacter-jejuni-evaluated-with-pcr-based-methods
#1
Anja Klančnik, Špela Zorko, Nataša Toplak, Minka Kovač, Franz Bucar, Barbara Jeršek, Sonja Smole Možina
The food-borne pathogen Campylobacter jejuni can cause bacterial gastrointestinal infections. Biofilm formation amplifies the risk of human infection by improving survival and persistence of C. jejuni in food processing environments and its transmission through the food chain. We aimed to control C. jejuni using an alternative strategy of low doses of Juniperus communis fruit preparations to target bacterial adhesion properties in the first step of biofilm formation. First, we defined the anti-Campylobacter activity of a juniper fruit crude extract and its fractionated biflavonoids, flavone glycosides, and purified amentoflavone, of juniper fruit essential oil and of juniper fruit postdistillation waste material extract...
December 19, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29250843/insulin-resistance-improvement-by-cinnamon-powder-in-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-clinical-trial
#2
Mahdie Hajimonfarednejad, Majid Nimrouzi, Mojtaba Heydari, Mohammad Mehdi Zarshenas, Mohammad Javad Raee, Bahia Namavar Jahromi
Our aim is to assess the effect of cinnamon powder capsules on insulin resistance, anthropometric measurements, glucose and lipid profiles, and androgens of women with polycystic ovarian syndrome (PCOS). Out of 80 women that were diagnosed as PCOS by Rotterdam Criteria, 66 were enrolled in this randomized double-blind placebo-controlled clinical trial. All of the PCOS women were taking medroxy progesterone acetate 10 mg/day for the last 10 days of their menstrual cycles. The cases were randomly allocated to 2 groups...
December 18, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29250842/phytotherapeutic-effects-of-the-fruits-of-poncirus-trifoliata-l-raf-on-cancer-inflammation-and-digestive-dysfunction
#3
REVIEW
Yongwoo Jang, Eun-Kyung Kim, Won-Sik Shim
Poncirus trifoliata (L.) Raf. belongs to the family Rutaceae in the genus Poncirus. Its fruits are widely used to alleviate symptoms of various disorders. The mature fruit (MF) possesses anticancer and antiinflammatory activities. Extracts of the dried, immature fruit, Poncirus fructus (PF) are widely used as a traditional medicine for ameliorating symptoms of digestive dysfunction in East Asia. Molecular and cellular mechanisms underlying the effects of MF and PF extracts on cancer, inflammation, and gastrointestinal disorders have been extensively studied in the past decade...
December 18, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29250830/suppressive-activities-and-mechanisms-of-ugonin-j-on-vascular-smooth-muscle-cells-and-balloon-angioplasty-induced-neointimal-hyperplasia
#4
Chun-Hsu Pan, Pei-Chuan Li, Yi-Chung Chien, Wan-Ting Yeh, Chih-Chuang Liaw, Ming-Jyh Sheu, Chieh-Hsi Wu
Neointimal hyperplasia (or restenosis) is primarily attributed to excessive proliferation and migration of vascular smooth muscle cells (VSMCs). In this study, we investigated the inhibitory effects and mechanisms of ugonin J on VSMC proliferation and migration as well as neointimal formation. Cell viability and the cell-cycle distribution were, respectively, analyzed using an MTT assay and flow cytometry. Cell migration was examined using a wound-healing analysis and a transwell assay. Protein expressions and gelatinase activities were, respectively, measured using Western blot and gelatin zymography...
December 18, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29243333/psoralea-corylifolia-l-ethnobotanical-biological-and-chemical-aspects-a-review
#5
REVIEW
Fiaz Alam, Gul Nawaz Khan, Muhammad Hassham Hassan Bin Asad
Psoralea corylifolia L. (Leguminosae) is a well-known traditional medicinal plant used from ancient times for treatment of various ailments. It is widely distributed and an important part of therapeutics in Ayurveda and in Chinese medicines. The aim of this review is to present comprehensive and most up to date report on its ethnobotanical, ethnopharmacological, clinical, phytochemical, and side effects. Studies on the ethnobotanical, ethnopharmacological, clinical, phytochemical, and side effects of P. corylifolia were published until year 2017 and were searched using various scientific databases...
December 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29243310/coriolus-versicolor-aqueous-extract-ameliorates-insulin-resistance-with-pi3k-akt-and-p38-mapk-signaling-pathways-involved-in-diabetic-skeletal-muscle
#6
Hui-Min Xian, Hui Che, Ying Qin, Fan Yang, Song-Yan Meng, Xiao-Guang Li, Yun-Long Bai, Li-Hong Wang
Patients with type 2 diabetes mellitus (T2DM) are usually with poor immunity and easier to suffer from cancer and microbial infections. Herein, we report an efficient anti-diabetic medicinal mushroom, Coriolus versicolor (CV). This study aimed to investigate the anti-diabetic and anti-insulin-resistance effects of CV aqueous extract in myoblasts (L6 cells) and skeletal muscle of T2DM rat. Our results showed that CV extract treatment significantly reduced blood glucose levels of T2DM rats, whereas CV extract increased glucose consumption in insulin resistant L6 cells...
December 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29243308/western-herbal-medicine-consultations-for-common-menstrual-problems-practitioner-experiences-and-perceptions-of-treatment
#7
Carole Fisher, Jon Adams, Jane Frawley, Louise Hickman, David Sibbritt
To explore the prevalence with which Australian Western herbalists treat menstrual problems and their related treatment, experiences, perceptions, and interreferral practices with other health practitioners. Members of the Practitioner Research and Collaboration Initiative practice-based research network identifying as Western Herbalists (WHs) completed a specifically developed, online questionnaire. Western Herbalists regularly treat menstrual problems, perceiving high, though differential, levels of effectiveness...
December 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29243291/antiinflammatory-properties-of-betulinic-acid-and-xylopic-acid-in-the-carrageenan-induced-pleurisy-model-of-lung-inflammation-in-mice
#8
Edmund Ekuadzi, Robert P Biney, Charles K Benneh, Bismark Osei Amankwaa, Jonathan Jato
This study investigated the antiinflammatory properties of betulinic acid (BA) and xylopic acid (XA) extracted from Margaritaria discoidea and Xylopia aethiopica, respectively. M. discoidea and X. aethiopica are plants native in Ghana and the West-African region and used traditionally to treat different pathologies including inflammatory conditions. The antiinflammatory effect of BA and XA was established by an in vivo assay using the carrageenan-induced pleural inflammation model in mice. Also, the ability of BA and XA to increase catalase, superoxide dismutase, glutathione levels and decrease lipid peroxidation level in reactive oxidative assays was assessed...
December 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29235181/fuzheng-huayu-capsule-as-an-adjuvant-treatment-for-hbv-related-cirrhosis-a-systematic-review-and-meta-analysis
#9
REVIEW
Tao Wang, Xuelin Zhou, Honghong Liu, Jiabo Wang, Ping Zhang, Yun Zhu, Kun Li, Shizhang Wei, Haotian Li, Lifu Wang, Ruilin Wang, Yanling Zhao
Fuzheng Huayu (FZHY) capsule, a formulated traditional Chinese medicine product with 6 Chinese herbs, is widely used for HBV-related cirrhosis as an adjuvant treatment. However, the efficacy of FZHY capsule for HBV-induced cirrhosis did not be comprehensively proved by systematic analysis. Our current analysis was aimed to assess the efficacy and safety of FZHY capsule by an evidence-based method. Databases, including China National Knowledge Infrastructure, Wangfang, VIP medicine information system, Pubmed, Embase, and Cochrane Library, were searched, and the randomized controlled trials of FZHY capsule were used for the treatment of HBV-associated liver cirrhosis...
December 13, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29235180/the-effects-of-hypoglycemia-and-weight-loss-of-total-lignans-from-fructus-arctii-in-kkay-mice-and-its-mechanisms-of-the-activity
#10
Yingying Gao, Chenchen Gu, Kai Wang, Haiying Wang, Kefeng Ruan, Zhaohui Xu, Yi Feng
Fructus Arctii (great burdock achene) is the dried ripe fruit of Arctium lappa L. (family Asteraceae) and is included in the Chinese pharmacopoeia. It has been reported that the clinical use of Fructus Arctii resulted in a satisfactory hypoglycemic effect in diabetic patients. This study aimed to investigate antidiabetic activity and mechanism of total lignans from Fructus Arctii (TLFA) in KKAy mice, a spontaneous Type 2 diabetic rodent model that exhibits marked obesity. In this study, KKAy mice were gavaged once daily with solvents (0...
December 13, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29235162/iron-chelating-effect-of-silymarin-in-patients-with-%C3%AE-thalassemia-major-a-crossover-randomised-control-trial
#11
Hadi Darvishi-Khezri, Ebrahim Salehifar, Mehrnoush Kosaryan, Hossein Karami, Mohammadreza Mahdavi, Abbas Alipour, Aily Aliasgharian
This study aimed to determine the potential iron-chelating effects of silymarin in patients with β-thalassemia major receiving standard iron-chelation therapy. We evaluated whether addition of silymarin to standard iron-chelation therapy could improve iron burden markers and liver and cardiac function in these patients, via a placebo-controlled, crossover clinical study. Silymarin (140 mg) or placebo were administered thrice daily to all patients (n = 82) for 12 weeks, and after a 2-week washout period, patients were crossed over to the other groups...
December 13, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29235159/the-effect-of-green-tea-ointment-on-episiotomy-pain-and-wound-healing-in-primiparous-women-a-randomized-double-blind-placebo-controlled-clinical-trial
#12
Hadis Shahrahmani, Nourossadat Kariman, Sharareh Jannesari, Mahmoud Rafieian-Kopaei, Moghadameh Mirzaei, Sahar Ghalandari, Nasim Shahrahmani, Gashtasb Mardani
The delayed healing of episiotomy wound and its associated pain is a major problem in obstetrics. Because green tea has analgesic and wound-healing properties, the present study was conducted to determine the effect of green tea ointment on episiotomy pain and wound-healing. The green tea extract was also standardized by measuring its Phenolic and flavonoid compounds, antioxidant activity, and one of its active components, that is, Epigallocatechin gallate. The present clinical trial was conducted on 99 primiparous women visiting Afzalipour Hospital in Kerman in 2015...
December 13, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29235165/melaleuca-alternifolia-and-its-application-against-dental-plaque-and-periodontal-diseases-a-systematic-review
#13
REVIEW
Maísa Casarin, Josiele Pazinatto, Roberto Christ Vianna Santos, Fabricio Batistin Zanatta
This is a systematic review of clinical and laboratory studies evaluating the effect of Melaleuca alternifolia on periodontopathogens, dental plaque, gingivitis, periodontitis, and inflammatory responses. The PubMed, Cochrane, Web of science, Bireme, Lilacs, Prospero, Open Grey, and Clinical Trials databases were searched to identify potentially eligible studies through October 2016. Of 1,654 potentially eligible studies, 25 were included in the systematic review. Their methodology was evaluated through the Cochrane Handbook for clinical studies and the GRADE system for in vivo/in vitro studies...
December 12, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29226586/protective-effect-of-gentiopicroside-from-gentiana-macrophylla-pall-in-ethanol-induced-gastric-mucosal-injury-in-mice
#14
Yang Yang, Ziye Wang, Li Zhang, Bing Yin, Le Lv, Jiao He, Ziyang Chen, Xin Wen, Boling Qiao, Wenji Sun, Minfeng Fang, Yongmin Zhang
Gentiopicroside isolated from gentiana macrophylla Pall. belongs to iridoid glycosides. This study aimed to evaluate the protective effect of gentiopicroside against ethanol-induced gastric mucosal injury in mice. Mice were proactively administrated with gentiopicroside by intragastric administration once a day for 3 consecutive days. On the 3rd day, gastric ulcer in mice was induced with 70% ethanol after the last intragastric administration. The stomach tissues were submitted for evaluation of the severity of gastric mucosal alterations...
December 11, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29226489/inhibitory-effect-of-sulphated-polysaccharide-porphyran-isolated-from-porphyra-yezoensis-on-rankl-induced-differentiation-of-raw264-7-cells-into-osteoclasts
#15
Mikinori Ueno, Kichul Cho, Shogo Isaka, Tomoki Nishiguchi, Kenichi Yamaguchi, Daekyung Kim, Tatsuya Oda
Safe and efficient therapeutic agents for bone diseases are required in natural sources. We previously found that edible seaweed-derived polysaccharide porphyran exhibited anti-inflammatory effects through the down regulation of nuclear factor-κB. The aim of this study was to investigate the availability of porphyran as a therapeutic agent for bone diseases. The effects of porphyran on receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclastogenesis in RAW264.7 cells were examined. Porphyran suppressed RANKL-induced osteoclast formation in a concentration-dependent manner (6...
December 11, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29226479/metabolite-profiling-and-isolation-of-biologically-active-compounds-from-scadoxus-puniceus-a-highly-traded-south-african-medicinal-plant
#16
Devashan Naidoo, Lenka Poštová Slavětínská, Adeyemi O Aremu, Jiri Gruz, Ondrej Biba, Karel Doležal, Johannes Van Staden, Jeffrey F Finnie
Scadoxus puniceus (Amaryllidaceae), a medicinal plant of high value in South Africa, is used as a component of a traditional herbal tonic prescribed to treat several ailments. Ultra-high performance liquid chromatography-tandem mass spectrometry quantified the phenolic compounds in different organs of S. puniceus. Gravity column chromatography was used to separate fractions and active compounds. The structure of these compounds was determined using 1D and 2D nuclear magnetic resonance and mass spectroscopic techniques...
December 11, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29214691/photoactive-plants-botany-bad-boys-or-horticultural-heroes
#17
LETTER
Mark Wainwright, William J Stockburn, Clare L Lawrence, Harry J Stevens, Allison E Jones, Robert B Smith
No abstract text is available yet for this article.
December 7, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29214686/myricetin-attenuated-lps-induced-cardiac-injury-in-vivo-and-in-vitro
#18
Nan Zhang, Hong Feng, Hai-Han Liao, Si Chen, Zheng Yang, Wei Deng, Qi-Zhu Tang
Sepsis induced myocardial dysfunction (SIMD) is a common complication and leads to an increased mortality. SIMD is closely related to inflammation and oxidative stress. Myricetin exhibits strong capacities of anti-inflammation and anti-oxidative stress, but its pharmacological effects for lipopolysaccharide (LPS) induced cardiac injury remains undefined. This study aimed to explore whether myricetin was efficient to alleviate SIMD in mice and neonatal rat cardiomyocytes injury. Mice administrated with myricetin (100 mg/kg, po, bid) or vehicle groups were challenged with LPS (10 mg/kg, ip), and cardiac functions examined by echocardiography after 12 hr LPS exposure...
December 7, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29210124/a-novel-herbal-composition-containing-extracts-of-boswellia-serrata-gum-resin-and-aegle-marmelos-fruit-alleviates-symptoms-of-asthma-in-a-placebo-controlled-double-blind-clinical-study
#19
Pothina Yugandhar, Konda Manikyeswara Rao, Krishanu Sengupta
LI13109F is a novel herbal composition containing the extracts of Boswellia serrata gum resin and Aegle marmelos fruit. This composition dampens leukotriene dependent inflammatory reactions via inhibiting 5-lipoxygenase pathway. In a Sephadex LH-20 induced airway inflammation model of Sprague Dawley rats, LI13109F significantly reduced infiltrated granulocyte population in the bronco-alveolar lavage fluid and normalized Th1/Th2 cytokine balance. Further, a 56-day placebo-controlled and randomized double blind study (Clinical Trial Registration No...
December 6, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29210121/proanthocyanidin-rich-pinus-radiata-bark-extract-inhibits-mast-cell-mediated-anaphylaxis-like-reactions
#20
Yun Ho Choi, Chang Ho Song, Sung Phil Mun
Mast cells play a critical role in the effector phase of immediate hypersensitivity and allergic reactions. Pinus radiata bark extract exerts multiple biological effects and exhibits immunomodulatory and antioxidant properties. However, its role in mast cell-mediated anaphylactic reactions has not been thoroughly investigated. In this study, we examined the effects of proanthocyanidin-rich water extract (PAWE) isolated from P. radiata bark on compound 48/80-induced or antidinitrophenyl (DNP) immunoglobulin E (IgE)-mediated anaphylaxis-like reactions in vivo...
December 6, 2017: Phytotherapy Research: PTR
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