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Journal of Clinical Dentistry

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https://www.readbyqxmd.com/read/28657703/a-randomized-clinical-trial-to-measure-mouth-moisturization-and-dry-mouth-relief-in-dry-mouth-subjects-using-dry-mouth-products
#1
Anto Jose, Mounir Atassi, Lucy Shneyer, Matthew Cronin
OBJECTIVES: This study examined ratings of two subjective aspects (moisturization and dry mouth relief) that may be changed following the use of dry mouth relief products (an oral gel, an oral rinse, or a mouth spray), in comparison to water over a period of four hours following a single supervised use on two separate occasions. METHODS: This was a single-center, two site, randomized, examiner blind, four treatment arm, stratified (by dry mouth screening score at baseline), parallel group study in healthy subjects with a self-reported feeling of dry mouth...
June 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28657702/in-situ-study-to-confirm-the-anticaries-potential-of-a-sodium-monofluorophosphate-dentifrice-containing-calcium-sodium-phosphosilicate
#2
C R Parkinson, M Siddiqi, S Mason, F Lippert, A T Hara, D T Zero
OBJECTIVES: A randomized, investigator-blind, five-treatment, crossover, non-inferiority study was conducted to investigate the effect of the addition of calcium sodium phosphosilicate (CSPS), an agent known to relieve dentin hypersensitivity, to a sodium monofluorophosphate (SMFP)-containing dentifrice on the enamel remineralization potential of fluoride (F), as assessed by percentage surface microhardness recovery (%SMHR) and enamel fluoride uptake (EFU) using a standard in situ caries model...
June 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28657701/clinical-effects-of-stabilized-stannous-fluoride-dentifrice-in-reducing-plaque-microbial-virulence-i-microbiological-and-receptor-cell-findings
#3
Malgorzata Klukowska, John Christian Haught, Sancai Xie, Ben Circello, Cheryl S Tansky, Deepa Khambe, Tom Huggins, Donald J White
OBJECTIVES: Lipopolysaccharides (LPSs) and lipoteichoic acids (LTAs), or bacterial endotoxins, bind with Toll-like receptors (TLRs) that are expressed on host cells of the periodontium, thereby contributing to the periodontal pathogenicity of oral bacteria. Stannous fluoride (SnF2), an antibacterial fluoride that treats and controls gingivitis, has been shown to react with lipophilic domains/anionic charges in LPS and LTA. The effects of bacterial species and dental plaque on toll receptors can be studied using genetically engineered cell lines containing linked toll receptors on their surfaces...
June 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28657700/a-randomized-clinical-study-to-evaluate-the-efficacy-of-an-experimental-3-75-w-w-potassium-chloride-dentifrice-for-the-relief-of-dentin-hypersensitivity
#4
Sarah Young, Nan Wang, Stephen Mason, Farzana Sufi
OBJECTIVES: To evaluate the clinical efficacy of an experimental "Test" dentifrice containing 3.75% (w/w) potassium chloride (KCl) in reducing dentin hypersensitivity (DH) compared with that of a standard fluoride "Reference" dentifrice after eight weeks' twice-daily brushing. METHODS: This was a randomized, controlled, examiner-blind, stratified, parallel-group, single-center study in healthy subjects with selfreported and clinically diagnosed DH. After an initial lead-in period, subjects were randomized to either the Test (n = 67) or the Reference dentifrice (n = 66) and instructed to brush twice daily for the next eight weeks...
June 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28657699/randomized-controlled-trial-to-explore-the-effect-of-experimental-low-abrasivity-dentifrices-on-enamel-gloss-and-smoothness-and-the-build-up-of-extrinsic-tooth-stain
#5
Kimberly R Milleman, Jeffery L Milleman, Sarah Young, Charles Parkinson
OBJECTIVES: To evaluate and compare examiner-assessed changes in enamel gloss, extrinsic dental stain, and surface smoothness following one, two, four, and eight weeks of twice-daily use of an experimental low abrasivity desensitizing dentifrice (relative dentin abrasivity [RDA] ~40) containing 5% sodium tripolyphosphate (STP) chemical cleaning agent and 1% aluminum trioxide abrasive. This was compared with an ultra-low abrasivity dentifrice (5% STP only; RDA ~13), a moderate abrasivity fluoride dentifrice (RDA ~80), and a higher abrasivity marketed whitening dentifrice (RDA ~142)...
June 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28422463/gingival-health-and-plaque-regrowth-response-following-a-four-week-interdental-hygiene-intervention
#6
Anthony Mwatha, Misty Olson, Sonia Souza, Marilyn Ward, Wendy Jenkins, Pejmon Amini, John Gallob, Theresa Fafard
OBJECTIVES: To compare the efficacy of three adjunct interproximal cleaning methods versus a manual toothbrush alone on gingivitis, and demonstrate that the Philips Sonicare AirflossPro™ interproximal (IP) cleaning device provides a similar reduction in gingivitis and plaque compared to string floss. METHODS: A randomized, single-blind, parallel-design study was conducted on generally healthy adults exhibiting mild to moderate gingivitis. Eligible subjects were non-smokers, aged 18-65 years, with ≥ 0...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28422462/a-comparison-of-the-effect-of-two-power-toothbrushes-on-the-gingival-health-and-plaque-status-of-subjects-with-moderate-gingivitis
#7
Michelle Starke, Marcia Delaurenti, Marilyn Ward, Sonia Souza, Kimberly R Milleman, Jeffery L Milleman
OBJECTIVES: To compare the effect of the Philips Sonicare DiamondClean plus Premium plaque control brush head with the Oral-B 7000 plus CrossAction brush head on gingivitis and supragingival plaque reduction following a 42-day period of home use. METHODS: This was a randomized, parallel, examiner-blind, prospective clinical trial conducted on generally healthy subjects. Eligible subjects met the following eligibility criteria: age 18-65, non-smoker, routine manual toothbrush user, ≥ 50 sites of gingival bleeding per the Gingival Bleeding Index (GBI), and ≥ 1...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28422461/the-effectiveness-of-manual-versus-high-frequency-high-amplitude-sonic-powered-toothbrushes-for-oral-health-a-meta-analysis
#8
M de Jager, A Rmaile, O Darch, J W Bikker
OBJECTIVES: Evaluate the short-term clinical efficacy of high-frequency, high-amplitude sonic powered toothbrushes compared to manual toothbrushes on plaque removal and gingivitis reduction in everyday use through a meta-analysis of randomized controlled trials. METHODS: Embase, MEDLINE, BIOSIS, Inspec, PQ SciTech, Compendex, SciSearch and IADR abstracts databases were searched. Eligible were clinical trials comparing at least one manual to one sonic powered toothbrush on plaque or gingivitis reduction over four weeks to three months in subjects without disability that could affect tooth brushing...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28422460/an-evaluation-of-plaque-and-gingivitis-reduction-following-home-use-of-sonicare-flexcare-platinum-with-premium-plaque-control-brush-head-and-a-manual-toothbrush
#9
Wendy Jenkins, Sonia Souza, Marilyn Ward, Jodi Defenbaugh, Kimberly R Milleman, Jeffery L Milleman
OBJECTIVES: To assess the effect of the Philips Sonicare FlexCare Platinum with Premium plaque control brush head on gingival inflammation, bleeding, and supragingival plaque reduction following a six-week period of home use compared to a manual toothbrush. METHODS: This was a randomized, single-blind, parallel-design clinical trial. Subjects included in the study were routine manual toothbrush users who were generally healthy non-smokers, aged 18-65 years, with mild to moderate gingivitis...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28422459/the-effect-of-use-of-a-sonic-power-toothbrush-and-a-manual-toothbrush-control-on-plaque-and-gingivitis
#10
Marcia Delaurenti, Marilyn Ward, Sonia Souza, Wendy Jenkins, Mark S Putt, Kimberly R Milleman, Jeffery L Milleman
OBJECTIVES: To compare the ability of the Philips Sonicare DiamondClean power toothbrush and the ADA Reference manual toothbrush to reduce plaque and gingival inflammation by routine manual toothbrush users. METHODS: This was a randomized, single-blind, parallel-design study. Eligible subjects were generally healthy non-smokers who exhibited mild to moderate gingivitis upon study entry. Enrolled subjects were randomly allocated to commence twice-daily home use of either a Philips Sonicare DiamondClean (DiamondClean) power toothbrush or an ADA reference manual toothbrush (MTB) for a period of four weeks...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28391665/a-randomized-controlled-clinical-trial-to-evaluate-extrinsic-stain-removal-of-a-whitening-dentifrice
#11
Géza Terézhalmy, Tao He, Mary Kay Anastasia, Rachelle Eusebio
OBJECTIVES: To evaluate the extrinsic stain removal efficacy of a new whitening dentifrice containing sodium hexametaphosphate (SHMP) over a two-week period. METHODS: This study used a controlled and randomized, examiner-blind, single-center, two-treatment, parallel group design. Subjects with visible extrinsic dental stain on facial surfaces of their anterior teeth, and meeting all study criteria, were entered into the trial. The test group received the whitening dentifrice with sodium fluoride and SHMP and an ADA reference soft manual toothbrush...
December 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28391664/effect-of-green-tea-added-tablets-on-volatile-sulfur-containing-compounds-in-the-oral-cavity
#12
Pier Francesco Porciani, Simone Grandini
OBJECTIVES: A controlled, clinical, double-blind, cross-over study was conducted to assess the efficacy of sugar-free tablets containing green tea extract on oral volatile sulfur-containing compounds (VSC) versus placebo tablets for 30 minutes. METHODS: To join the study, subjects had to have at least 24 teeth, no report of oral and systemic diseases, and no removable dentures. All eligible participants had to avoid professional oral hygiene and drugs for two weeks, to not be menstruating, to avoid brushing their teeth and tongue, to not smoke, to not consume alcohol, coffee or tea, nor onion, garlic, or licorice for six hours before the test...
December 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28391663/a-comparative-study-of-laboratory-dentifrice-abrasion-measuring-methods
#13
Michael Prencipe, Mark Vandeven, Brian N Feldman, Bruce R Schemehorn
OBJECTIVES: Recently, a profilometry-based method for measuring toothpaste dentin abrasivity has been proposed to be equivalent to the traditional radiotracer RDA (relative dentin abrasion) procedure. This review outlines the findings and comparative assessment of laboratory studies used to measure the abrasivity of commercially available whitening dentifrices on human dentin. Traditional radiotracer and profilometry RDA-PE (Profilometry Equivalent) methods were assessed, with the objective of determining how they compare, and also to learn if the two techniques yield RDA values that are consistent with each other, specifically in ranking and potential for discrimination of three commercially available silica-based products...
December 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28391662/a-randomized-non-inferiority-clinical-study-to-evaluate-the-efficacy-of-two-dentifrices-for-dentin-hypersensitivity
#14
Sarah Young, Farzana Sufi, Muhammad Siddiqi, Robert Maclure, Jonathan Holt
OBJECTIVES: Calcium sodium phosphosilicate (CSPS) is a particulate bioactive material incorporated into oral healthcare products for the treatment of dentin hypersensitivity (DH). This study aimed to determine whether a dentifrice containing 5% CSPS and fluoride as sodium fluoride (NaF; "Test dentifrice") was non-inferior to a dentifrice containing 5% CSPS and fluoride as sodium monofluorophosphate (SMFP; "Comparator dentifrice") in reducing DH after eight weeks' twice-daily brushing...
December 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28391661/a-randomized-clinical-study-to-evaluate-the-efficacy-of-an-8-w-w-strontium-acetate-dentifrice-in-providing-relief-from-dentinal-hypersensitivity
#15
Peng Zang, David Shaw
OBJECTIVES: To evaluate the clinical efficacy of a dentifrice containing 8% strontium acetate in the relief of dentinal hypersensitivity (DH), compared with that of a standard fluoride dentifrice, in a Chinese population. METHODS: This was an eight-week, single-center, randomized, controlled, examiner-blind, parallel-group study in healthy adult volunteers with DH. After an initial acclimatization period, subjects were randomized to receive either a test dentifrice containing 8% strontium acetate with 1040 ppm fluoride as sodium fluoride, or a commercially available regular fluoride dentifrice containing 1400 ppm fluoride as sodium monofluorophosphate with no known anti-sensitivity activity (negative control)...
December 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390203/lipopolysaccharide-and-lipoteichoic-acid-virulence-deactivation-by-stannous-fluoride
#16
Chris Haught, Sancai Xie, Ben Circello, Cheryl S Tansky, Deepa Khambe, Malgorzata Klukowska, Tom Huggins, Donald J White
OBJECTIVES: Oral bacterial pathogens promote gingivitis and periodontal disease. Bacterial endotoxins, also known as lipopolysaccharides (LPSs) and lipoteichoic acids (LTAs), are known to enhance bacterial pathogenicity through binding with Toll-like receptors (TLRs), a group of pattern recognition receptors critical to the activation of innate immunity, that are expressed on host cells. Both LPS and LTA contain lipophilic domains and anionic charges that may be susceptible to reactivity with stannous fluoride, a commonly used ingredient clinically proven for the treatment and prevention of gingivitis...
September 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390202/clinical-study-to-determine-the-stain-removal-effectiveness-of-a-new-dentifrice-formulation
#17
A Buelo, A Ghassemi, L Vorwerk, W Hooper, S Nathoo
OBJECTIVES: This randomized, prospective clinical trial was conducted to determine the safety and effectiveness of a new whitening dentifrice formulation in comparison to that of both a negative and a positive control dentifrice. METHODS: Seventy-nine qualifying subjects were randomly assigned to either the new whitening dentifrice (Arm & Hammer® Truly Radiant™ Clean & Fresh Toothpaste), a positive control whitening dentifrice (Crest® 3-D White® Radiant Mint Toothpaste), or a negative control regular dentifrice (Colgate® Cavity Protection Toothpaste)...
September 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390201/comparative-plaque-removal-efficacy-of-a-new-powered-toothbrush-and-a-manual-toothbrush
#18
L Vorwerk, A Ghassemi, W Hooper, V Patel, J Milleman, K Milleman
OBJECTIVES: The purpose of this study was to determine the plaque removal effectiveness of a new powered toothbrush and compare it to that of a manual brush. METHODS: This examiner-blind, randomized study used a cross-over design. Sixty-two (62) qualifying subjects were randomly assigned either to the powered brush (Arm & Hammer Spinbrush™ Truly Radiant™ Clean & Fresh Battery-Powered Toothbrush), or a standard manual toothbrush (ADA Standard Manual Toothbrush) and instructed to brush at home with a standard fluoride toothpaste twice daily for two minutes during a one-week familiarization period...
September 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390200/comparative-plaque-removal-efficacy-of-three-manual-toothbrushes
#19
A Ghassemi, L Vorwerk, W Hooper, M Kwang, M Naji, C R Goyal, J Qaqish
OBJECTIVES: The purpose of this study was to determine the safety and plaque-reducing effectiveness of a newly designed manual toothbrush compared to that of a leading marketed toothbrush and a reference standard manual toothbrush control. METHODS: This examiner-blind, randomized, single-use study used a cross-over design. Sixty-eight qualifying male and female subjects were randomly assigned either an Arm & Hammer™ Truly Radiant™ Deep Clean manual toothbrush (TR), a Colgate® Extra Clean manual toothbrush (C), or an ADA reference standard manual toothbrush (SM) according to one of three computer-generated sequences...
September 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390199/efficacy-of-dentaq%C3%A2-oral-and-ent-health-probiotic-complex-on-clinical-parameters-of-gingivitis-in-patients-undergoing-fixed-orthodontic-treatment-a-pilot-study
#20
Duygu Kolip, Nuray Yılmaz, Berna Gökkaya, Pinar Kulan, Betul Kargul, Kyle W MacDonald, Peter A Cadieux, Jeremy P Burton, Kris M James
OBJECTIVES: Probiotics act as a unique approach to maintaining oral health by supplementing the endogenous oral bacteria with additional naturally occurring beneficial microbes to provide defense against pathogens harmful to teeth and gingiva. The aim of this pilot study was to clinically evaluate the effects of probiotics on plaque accumulation and gingival inflammation in subjects with fixed orthodontics. METHODS: The pilot study was comprised of 15 healthy patients, aged 11 to 18 years, undergoing fixed orthodontic treatment...
September 2016: Journal of Clinical Dentistry
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