Ana F B Silva, Ana N P Morais, Laritza F Lima, Anna C A Ferreira, Renato F Silva, Naiza A R Sá, Satish Kumar, Ariclécio C Oliveira, Benner G Alves, Ana P R Rodrigues, Eduardo L Gastal, Vilceu Bordignon, José R Figueiredo
This study assessed the histones methylation profile (H3K4me3 and H3K9me3) in late preantral (PA) and early antral (EA) caprine follicles grown in vivo and in vitro, and the anethole effect during in vitro culture of PA follicles. Uncultured in vivo-grown follicles (PA, n = 64; EA, n = 73) were used as controls to assess the methylation profile and genes' expression related to apoptosis cascade (BAX, proapoptotic; BCL2, antiapoptotic), steroidogenesis (CYP17, CYP19A1), and demethylation (KDM1AX1, KDM1AX2, KDM3A)...
September 6, 2023: Molecular Reproduction and Development