Usende Ifukibot Levi, Mofio M Bintu, Osinachi Chinonyerem Daniella, Oyelowo-Abdulraheem Fatima Oyenike, Adikpe Oluwa Agbonu, Azeez Mariam Adedamola, Enefe Ndidi, Sanni Fatimah Saka, Beselia V Gela, Smart I Mbagwu, Edem Ekpenyong Edem, Olopade James Olukayode, Connor James
Concerns about inappropriate disposal of waste into unsanitary municipal solid waste landfills around the world have been on the increase, and this poses a public health challenge due to leachate production. The neurotoxic effect of Gwagwalada landfill leachate (GLL) was investigated in male adult Wistar rats. Rats were exposed to a 10% concentration of GLL for 21 days. The control group received tap water for the same period of the experiment. Our results showed that neurobehavior, absolute body and brain weights and brain histomorphology as well as parvalbumin interneurons were severely altered, with consequent astrogliosis and microgliosis after 21 days of administrating GLL...
January 2, 2024: Journal of Chemical Neuroanatomy