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Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium

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https://www.readbyqxmd.com/read/27834189/magnesium-in-metabolic-syndrome-a-review-based-on-randomized-double-blind-clinical-trials
#1
Fernando Guerrero-Romero, Francia O Jaquez-Chairez, Martha Rodríguez-Morán
A growing body of evidence shows the effect of magnesium on serum glucose, HDL-cholesterol, and triglycerides levels, as well as on blood pressure, which strongly suggests that magnesium might play an important role in metabolic syndrome (MetS), a cluster of risk factors for cardiovascular disease and type 2 diabetes. We performed a systematic review of clinical evidence derived from randomized, double-blind, controlled clinical trials, regarding the efficacy of magnesium supplementation on the components of MetS...
November 10, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27624533/changes-in-circulating-levels-of-fibroblast-growth-factor-23-induced-by-short-term-dietary-magnesium-deficiency-in-rats
#2
Hiroshi Matsuzaki, Shinichi Katsumata, Yoshiaki Maeda, Yasutaka Kajita
Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphorus (P) and vitamin D metabolism. Long-term dietary magnesium (Mg) deficiency increases circulating levels of FGF23, whereas the effects of short-term dietary Mg deficiency are unclear. Thus, the present study investigated whether short-term dietary Mg deficiency affects circulating levels of FGF23. We also assessed changes in renal mRNA expression of vitamin D metabolizing enzymes and type II sodium-phosphate (Na/Pi) cotransporters, since these are regulated by FGF23...
June 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27624532/hypomagnesemia-associated-with-hypocalcemia-after-total-thyroidectomy-an-observational-study
#3
Renata Regina da Graça Lorencetti Mahmoud, Vergilius José Furtado de Araujo Neto, Wellington Alves, Chin Shien Lin, Ana Kober Nogueira Leite, Leandro Luongo Matos, Vergilius José Furtado de Araujo Filho, Claudio Roberto Cernea
INTRODUCTION: Serum magnesium is frequently low in patients with hypocalcemia after total thyroidectomy. The aim of the present study was to analyze the variations in serum magnesium and calcium concentrations after total thyroidectomy, and the relationship between both ions. MATERIALS AND METHODS: We conducted an observational study of 142 patients who had undergone total thyroidectomy, measuring serum calcium and magnesium levels preoperatively and on the day following surgery...
June 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27624531/permeation-of-topically-applied-magnesium-ions-through-human-skin-is-facilitated-by-hair-follicles
#4
Navin Chandrakanth Chandrasekaran, Washington Y Sanchez, Yousuf H Mohammed, Jeffrey E Grice, Michael S Roberts, Ross T Barnard
Magnesium is an important micronutrient essential for various biological processes and its deficiency has been linked to several inflammatory disorders in humans. Topical magnesium delivery is one of the oldest forms of therapy for skin diseases, for example Dead Sea therapy and Epsom salt baths. Some anecdotal evidence and a few published reports have attributed amelioration of inflammatory skin conditions to the topical application of magnesium. On the other hand, transport of magnesium ions across the protective barrier of skin, the stratum corneum, is contentious...
June 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27624530/call-for-unpublished-findings
#5
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27910809/magnesium-in-health-disease
#6
(no author information available yet)
No abstract text is available yet for this article.
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27910808/magnesium-and-depression
#7
Anna Serefko, Aleksandra Szopa, Ewa Poleszak
Magnesium is one of the most important elements in the human body and is involved in a number of biochemical processes crucial for the proper functioning of the cardiovascular, alimentary, endocrine, and osteoarticular systems. It also plays a vital modulatory role in brain biochemistry, influencing several neurotransmission pathways associated with the development of depression. Personality changes, including apathy, depression, agitation, confusion, anxiety, and delirium are observed when there is a deficiency of this element...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27910807/magnesium-intake-and-depression-the-sun-cohort
#8
Miguel Ángel Martínez-González, Almudena Sánchez-Villegas
A higher magnesium intake may reduce the risk of depression. We analyzed this association in the SUN Mediterranean cohort with an expanded sample size (n = 15,836) and a long follow-up (median = 10.2 y). We followed 9,289 women (age = 34.8, SD = 10.4) and 6,547 men (age = 42.8, SD = 13.1) initially free of any history of depression for a new-onset of medically diagnosed depression (maximum follow-up = 15.9 y). All participants in this cohort were university educated. We systematically reviewed previous studies relating magnesium to depression...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27869100/the-effects-of-magnesium-supplementation-on-subjective-anxiety
#9
Neil Bernard Boyle, Clare L Lawton, Louise Dye
: Experimental studies of anxiety in animal models, and evidence of efficacious outcomes of magnesium (Mg) supplementation in the treatment of acute clinical affective disorders, has increased interest in Mg as a potential novel treatment for symptoms of mild/moderate subjective anxiety. This short review examines the existing evidence for the effects of Mg supplementation on subjective anxiety in humans. Additionally, evidence from three unpublished studies that examined Mg and vitamin B6 intake on subjective anxiety is summarised to supplement the existing literature...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27829572/magnesium-in-the-cns-recent-advances-and-developments
#10
Robert Vink
A potential neuroprotective role for magnesium in neurological disease has been appreciated for almost three decades, yet translation to the clinical arena has proven elusive. Accumulating experimental evidence continues to suggest that magnesium plays a critical role in a number of neurological conditions including headache, stress, alcohol/drug intoxication, acute brain injury, seizures, Parkinson's disease and Alzheimer's disease. Simple administration of a magnesium salt in these conditions has not always been therapeutically successful, with a number of studies showing poor penetration of serum magnesium across the blood brain barrier...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27829571/a-guided-tour-of-presentations-at-the-xiv-international-magnesium-symposium
#11
Andrea Rosanoff, Federica I Wolf
No abstract text is available yet for this article.
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27160490/comparison-of-the-antinociceptive-effect-of-systemic-versus-intrathecal%C3%A2-magnesium-sulphate-on-spinal-morphine-analgesia
#12
Medhat M Messeha, Vivian Boshra
The aim of this work was to compare the possible antinociceptive effect of the intravenous (IV) versus the intrathecal (IT) administration of magnesium sulphate prior to spinal morphine analgesia. This research was conducted in two sets: First; experimentally, to compare the antinociceptive effect of IT magnesium sulphate (375 μg/rat) versus IP magnesium sulphate 100 mg/kg), prior to IT morphine (10 μg/rat). Pain was assessed using Randall-Selitto testing, the hot-plate, and formalin tests. A non-significant difference in the nociceptive threshold was observed between IT and IP magnesium sulphate administration prior to IT morphine in rats...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27160489/extracellular-magnesium-and-calcium-blockers-modulate-macrophage-activity
#13
Patrycja Libako, Wojciech Nowacki, Sara Castiglioni, Andrzej Mazur, Jeanette A M Maier
Magnesium (Mg) possesses anti-inflammatory properties, partly because it antagonizes calcium (Ca) and inhibits L-type Ca channels. Our aim was to determine the effects of different concentrations of extracellular Mg, with or without Ca-channel blockers, in macrophages. A macrophage-like cell line J774.E was cultured in different concentrations of extracellular Mg and exposed to i) the phorbol ester PMA to induce the production of reactive oxygen species ii) lipopolysaccharide to induce the production of pro-inflammatory cytokines, or iii) ovalbumin to study endocytosis...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27086964/effect-of-proton-pump-inhibitors-on-magnesium-balance-is-there-a-link-to-cardiovascular-risk
#14
Laura Francesca Pisani, Elisabetta Filippi, Sara Vavassori, Nadia Munizio, Maurizio Vecchi, Luca Pastorelli
Magnesium (Mg(2+)) is the second most copious element inside human cells and the fourth most abundant positively charged ion in the human body. It is of central importance for a broad variety of physiological processes, including intracellular signaling, neuronal excitability, muscle contraction, bone formation and enzyme activation. Its overall balance is tightly regulated by the concerted actions of the intestine, bones and kidneys. Disturbance of this balance can have serious consequences. Symptoms of hypomagnesaemia include tetany, seizures and cardiac arrhythmias, whereas hypermagnesaemia may cause cardiovascular and neuromuscular abnormalities...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/26878253/an-approach-to-the-diagnosis-and-management-of-a-case-presenting-with-recurrent-hypomagnesemia-secondary-to-the-chronic-use-of-a-proton-pump-inhibitor
#15
Lívia Marcela dos Santos, Ricardo Ayello Guerra, Marise Lazaretti-Castro, José Gilberto H Vieira, Evandro de Souza Portes, Magnus R Dias-da-Silva
PURPOSE: Magnesium is an important electrolyte for very many cell functions and its deficiency may lead to a wide spectrum of diseases. We report a clinical case of hypomagnesemia resulting from the chronic use of a proton pump inhibitor (PPI). PPIs are drugs widely used in medical practice, and a growing number of cases of PPIs causing hypomagnesemia have been described. Our aim was to monitor the clinical and electrolyte findings during recovery from hypomagnesemia caused by long-term PPI use...
December 2015: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/26878252/hyperphosphatemia-hypocalcemia-and-increased-serum-potassium-concentration-as-distinctive-features-of-early-hypomagnesemia-in-magnesium-deprived-mice
#16
Bernardo Ortega, Jacob R MacWilliams, Jason M Dey, Valerie B Courtright
Magnesium-deficient patients show dysfunctional calcium (Ca(2+)) metabolism due to defective parathyroid hormone (PTH) secretion. In mice and rats, long-term magnesium (Mg(2+)) deprivation causes hyperphosphaturia and increases fibroblast growth factor 23 (FGF23) secretion, despite normal serum phosphate (Pi) and Ca(2+). Electrolyte disturbances during early hypomagnesemia may explain the response of mice to long-term Mg(2+) deprivation, but our knowledge of electrolyte homeostasis during this stage is limited...
December 2015: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/26878251/abdominal-obesity-and-gestational-diabetes-the-interactive-role-of-magnesium
#17
Ebrahim Mostafavi, Arash Aghajani Nargesi, Firoozeh Akbari Asbagh, Zaniar Ghazizadeh, Behnam Heidari, Hossein Mirmiranpoor, Alireza Esteghamati, Claude Vigneron, Manouchehr Nakhjavani
AIMS: Magnesium is a cofactor for numerous metabolic enzymatic reactions. It is required for glucose utilization and insulin signaling. We compared plasma magnesium concentrations in pregnant women with and without abdominal obesity, and investigated the interactive roles of magnesium and obesity in the development of gestational diabetes mellitus (GDM). METHODS: Pregnant women with and without abdominal obesity (n = 40 in each group) were followed during gestation...
December 2015: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/26507751/relationship-between-serum-magnesium-concentration-and-metabolic-and-hormonal-disorders-in-middle-aged-and-older-men
#18
Iwona Rotter, Danuta Kosik-Bogacka, Barbara Dołęgowska, Krzysztof Safranow, Beata Karakiewicz, Maria Laszczyńska
The aim of this study was to determine the relationship between serum magnesium (Mg) concentrations in middle-aged and older men, and the occurrence of selected metabolic and hormonal disorders. The study involved a total of 313 men aged 50-75 years, and who underwent standard anthropometric measurements. Also determined were blood serum Mg, lipid parameters - total cholesterol (TCh), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride (TG) and carbohydrate metabolism parameters - glucose, insulin (I)...
July 2015: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/26507750/magnesium-and-phase-angle-a-prognostic-tool-for-monitoring-cellular-integrity-in-judo-athletes
#19
Catarina N Matias, Cristina P Monteiro, Diana A Santos, Fátima Martins, Analiza M Silva, Maria J Laires, Luís B Sardinha
Adequate magnesium (Mg) levels play a vital role in membrane excitability, cell contractility and metabolism, being a key nutrient for sustaining appropriate muscular contraction and performance levels in athletes. Phase angle (PhA), assessed by bioimpedance analysis (BIA), has been reported to be positively associated with most nutritional markers and is an indicator of membrane integrity and water distribution between intra- and extracellular spaces. The aim of the present study was to verify the association between Mg status and PhA as a predictor of cellular health, in a sample of judo athletes from a period of weight stability to prior to competition...
July 2015: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/26446806/dietary-magnesium-the-magic-mineral-that-protects-from-colon-cancer
#20
COMMENT
Valentina Trapani, Federica I Wolf, Franco Scaldaferri
No abstract text is available yet for this article.
July 2015: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
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